<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.134266.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Fatalism and knowledge associated to diabetes mellitus type 2 risk perception in Mexican population during COVID-19 confinement</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 2 not approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Mendoza-Catal&#x00e1;n</surname>
                        <given-names>Geu</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>&#x00c1;lvarez Aguirre</surname>
                        <given-names>Alicia</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Dom&#x00ed;nguez Ch&#x00e1;vez</surname>
                        <given-names>Claudia Jennifer</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Tolentino Ferrel</surname>
                        <given-names>Mar&#x00ed;a del Rosario</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Villa Rueda</surname>
                        <given-names>Alma Ang&#x00e9;lica</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-2501-2820</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Guzm&#x00e1;n Ortiz</surname>
                        <given-names>Elizabeth</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-4944-0600</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Faculty of Nursing, Universidad Autonoma de Baja California, Mexicali, Baja California, 21280, Mexico</aff>
                <aff id="a2">
                    <label>2</label>Department of Clinical Nursing, Universidad de Guanajuato, Celaya, Guanajuato, 38050, Mexico</aff>
                <aff id="a3">
                    <label>3</label>Nursing and Obstetrics, Universidad de Guanajuato, Celaya, Guanajuato, 38050, Mexico</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:elizabeth.guzman@ugto.mx">elizabeth.guzman@ugto.mx</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>3</day>
                <month>7</month>
                <year>2023</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2023</year>
            </pub-date>
            <volume>12</volume>
            <elocation-id>771</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>21</day>
                    <month>6</month>
                    <year>2023</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2023 Mendoza-Catal&#x00e1;n G et al.</copyright-statement>
                <copyright-year>2023</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/12-771/pdf"/>
            <abstract>
                <p>
                    <bold>Background:</bold> People with fatalistic beliefs and lack of knowledge of healthy lifestyles tend to show conformism and resignation due to their state of health. Even people with fatalism consider that contracting a disease is divine punishment, and this is reflected when they perform in unhealthy behaviours. The relationship between fatalistic beliefs, knowledge about diabetes risk factors, and perceived risk of T2DM in Mexican adults during the COVID-19 pandemic were evaluated.</p>
                <p>
                    <bold>Methods:</bold> The study design was cross-sectional and correlational. The study included individuals between 30 and 70 years of age, from a rural community in Guanajuato, Mexico. The data collection was done electronically.</p>
                <p>
                    <bold>Results:</bold> The average age was 29.2 years (SD = 10.5), 55% were women, 52.3% were single, 36.2% had university studies and 57.3% were working. perceived risk of T2DM was inversely related to fatalistic beliefs. Knowledge level was positively correlated to perceived risk of T2DM. In multiple linear regression, pessimism and divine control dimensions were the only predictors of perceived risk of T2DM.</p>
                <p>
                    <bold>Conclusions:</bold> In young adults, knowledge increases regarding perceived risk of T2DM. But the higher the fatalistic beliefs the lower the level of knowledge and the lower the perceived risk of T2DM.</p>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Perception</kwd>
                <kwd>diabetes mellitus type 2</kwd>
                <kwd>fatalistic beliefs</kwd>
                <kwd>knowledge</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec1" sec-type="intro">
            <title>Introduction</title>
            <p>People with chronic diseases such as type 2 diabetes mellitus (T2DM) are the most vulnerable group of people for hospital incidence and mortality during the COVID-19 pandemic (coronavirus disease 2019).
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> Recent studies reported that during emergency care, people with COVID-19 were diagnosed as new cases of T2DM,
                <sup>
                    <xref ref-type="bibr" rid="ref3">3</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup> suggesting that people were unaware of their disease until admission to the hospital. Therefore, this situation may have generated concern in the general population about their health status and their perceived risk of T2DM.</p>
            <p>The perceived risk of T2DM is the individual&#x2019;s appreciation of the probability of developing the disease in the future. People who perceive a higher T2DM have more intention and adopt healthier lifestyles to prevent the disease.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> This type of risk perception increases in women, those who are older, have a family history of diabetes, are overweight/obese, consume sugary drinks, do not consume fruits and vegetables, have a previous diagnosis of hypertension, have knowledge about the risk factors for T2DM and have a poor perception of their health status.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>
                </sup>
                <sup>&#x2013;</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> However, a study conducted in Alemannia, reports that people with prediabetes and undiagnosed T2DM report low risk perception,
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup> the same as in the Mexican population.
                <sup>
                    <xref ref-type="bibr" rid="ref12">12</xref>
                </sup> The low risk perception of T2DM may be due to different factors such as beliefs that diseases are unpredictable, or fatalistic beliefs.
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> Fatalistic beliefs are considered as the idea that there is a force superior to the human being that determines the facts of life; this belief is referred to as external locus, luck, fate, destiny, or divine control.
                <sup>
                    <xref ref-type="bibr" rid="ref14">14</xref>
                </sup> People with fatalistic beliefs adopt pessimistic or despair behaviors, whose behavior results in thoughts that death and disease are inevitable.
                <sup>
                    <xref ref-type="bibr" rid="ref15">15</xref>
                </sup> This type of belief is considered an important coping factor when faced with the diagnosis of a chronic disease,
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> that is to say people with higher fatalistic beliefs use health services less, abandon treatments, and show higher mortality rates.
                <sup>
                    <xref ref-type="bibr" rid="ref17">17</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>
                </sup>
            </p>
            <p>Other studies report that fatalistic beliefs minimize and underestimate health risk because people do not comply with preventive behaviors,
                <sup>
                    <xref ref-type="bibr" rid="ref19">19</xref>
                </sup>
                <sup>&#x2013;</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref21">21</xref>
                </sup> for example, preventive measures to avoid infection by COVID-19, therefore people with fatalistic beliefs may underestimate the risk of chronic diseases such as T2DM. So far, the association between fatalistic beliefs, knowledge, and perceived risk of T2DM has not been demonstrated. How people perceive themselves and feel vulnerable to developing chronic diseases is a predictor for lifestyle change and disease prevention. However, fatalistic beliefs may be a factor that underestimates knowledge of risk factors and perceived risk of T2DM. Therefore, the aim of this research was to assess the relationship between fatalistic beliefs, knowledge regarding the risk factors of diabetes, and the perception of T2DM in Mexican adults during the COVID-19 pandemic.</p>
        </sec>
        <sec id="sec2" sec-type="methods">
            <title>Methods</title>
            <sec id="sec3">
                <title>Ethics and consent</title>
                <p>The study followed the guidelines of declaration of Helsinki and the General Health Law on health research in Mexico, and it was approved by the Ethics and Research Committee of the University of Guanajuato, Mexico with permit number DCSI-CI 20190308-3. Written informed consent was obtained from participants before their data was collected. Ethics approval was granted in 2019.</p>
            </sec>
            <sec id="sec4">
                <title>Design and participants</title>
                <p>The study design was cross-sectional and correlational. We had included adult men and women aged 30 to 70 years, residents of San Miguel Em&#x00e9;nguaro, Salvatierra, Guanajuato, Mexico. We had excluded persons with a diagnosis of type 1, type 2, and gestational diabetes. The sample was estimated using the statistical program G*power 3.1.4, with 95% reliability, 90% power and effect size of.08, which gave a sample of 218 people.</p>
            </sec>
            <sec id="sec5">
                <title>Data collection</title>
                <p>Participants were invited through online social networks (Facebook, WhatsApp and Instagram). The access link for the survey (hosted on Google Forms) was electronically shared through social networks. The invitation stated the objective of the survey, the declaration of respect for the confidentiality and anonymity of information, as well as that the survey was aimed at residents of San Miguel Em&#x00e9;nguaro, Salvatierra, Guanajuato. When the link was opened, the informed consent form with the option to agree to participate in the study was displayed first. Subsequently, information on sociodemographic data was requested and ended with the completion of the questionnaires. We restricted to survey to only allow one entry per person. Data collection was carried out from August to November 2020. The study followed the guidelines of declaration of Helsinki and the General Health Law on health research in Mexico.</p>
            </sec>
            <sec id="sec6">
                <title>Study variables</title>
                <p>Independent variables: fatalism and knowledge.</p>
                <p>Dependent variable: Perceived risk of Type 2 Diabetes Mellitus.</p>
            </sec>
            <sec id="sec7">
                <title>Questionnaires</title>
                <p>A sociodemographic data card was used to collect information such as age, sex, marital status, schooling, and occupation.</p>
                <p>To evaluate fatalism, the Multidimensional Fatalism Scale in Spanish
                    <sup>
                        <xref ref-type="bibr" rid="ref15">15</xref>
                    </sup> was used, with 30 statements grouped into five factors: fatalism, pessimism/hopelessness, internal locus, luck, and divine control with a response from 1 to 5, where 1 means frequently disagree and 5 means frequently agree, with a maximum score of 150 points and a minimum of 30 points. The higher the score, the greater the fatalism. Cronbach&#x2019;s alpha in this study was .88.</p>
                <p>In addition, we used of Risk Perception Survey for Developing Diabetes (RPS-DD), which contains 43 items that measures beliefs about one&#x2019;s risk for developing diabetes. This scale has six subscales: personal control (4 items), worry (2 items), optimistic bias (2 items), personal disease risk (15 items), comparative environment risk (9 items), and knowledge of diabetes risk factors (11 items). The higher the score the higher the perceived risk of T2DM.
                    <sup>
                        <xref ref-type="bibr" rid="ref22">22</xref>
                    </sup>
                    <sup>,</sup>
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>
                    </sup> To evaluate knowledge of risk factors, a subscale of the same instrument with 11 questions was used. Each question has 4 answers (increases the risk, has no effect on risk, decreases the risk and don&#x2019;t know). The items are dichotomously scored, correct/incorrect and the total sum of the subscale is from 0 to 11, the higher the score, the greater the knowledge.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>
                    </sup> Cronbach&#x2019;s alpha in this study was .76.</p>
            </sec>
            <sec id="sec8">
                <title>Statistical analysis</title>
                <p>SPSS version 25 was used to capture and assess data. Descriptive statistics were used for the characteristics of the participants, frequencies and percentages for categorical variables and measures of central tendency and dispersion for continuous variables. The variables of fatalistic beliefs (low 30 to 90; high 91 to 150), knowledge (low 0 to 4; high 5 to 9) and perceived risk of T2DM (low 8 to 20; high 21 to 32) were categorized according to the mean of the total score of the questionnaires. For the correlation analysis, Spearman&#x2019;s coefficient and multiple linear regression were used to explain the perceived risk of T2DM.</p>
            </sec>
        </sec>
        <sec id="sec9" sec-type="results">
            <title>Results</title>
            <sec id="sec10">
                <title>Sociodemographic characteristics</title>
                <p>In total 222 people participated in the survey, and 218 participants provided complete data. The average age was 29.2 years (SD=10.5), the sample was characterized by being mostly women (55%), single (52.3%), having a university education (36.2%) and having a job (53.7%), see 
                    <xref ref-type="table" rid="T1">Table 1</xref>.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>Table 1. </label>
                    <caption>
                        <title>Sociodemographic characteristics.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variable</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">f</italic> (%)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Sex</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Female</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">120 (55)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Male</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98 (45)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Marital status</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Single</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">114 (52.3)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Married</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">59 (27.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Common law marriage</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">30 (13.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Other</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">15 (6.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Schooling</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Elementary</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">21 (9.6)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Junior High</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51 (23.4)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;High School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">64 (29.4)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;University</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">82 (37.6)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Occupation</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Works</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">117 (53.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Studies</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">36 (16.5)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Works and studies</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">44 (20.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Unemployed</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">21 (9.6)</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>Note: 
                            <italic toggle="yes">n</italic>=218; 
                            <italic toggle="yes">f</italic>=frequency; %=percentage.</p>
                    </table-wrap-foot>
                </table-wrap>
                <p>Regarding fatalism, 27.5% report high fatalistic belief scores, 83.5% have high knowledge about T2DM risk factors and 66.1% have high perceived risk of developing T2DM; the measures of central tendency and dispersion of the variables are seen in 
                    <xref ref-type="table" rid="T2">Table 2</xref>.</p>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>Table 2. </label>
                    <caption>
                        <title>Description of fatalism, knowledge, and perceived risk of T2DM.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variables</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">M</italic> (SD)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Total fatalism</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">79.1 (15.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Pessimism</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">15.1 (4.0)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Luck</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">16.7 (3.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Divine control</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">17.2 (6.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Internal locus</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">11.8 (4.6)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Fatalism</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">18.1 (4.5)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Knowledge</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">6.9 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">T2DM risk perception</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">27.2 (3.3)</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>Note: 
                            <italic toggle="yes">n</italic>=218; M=mean; SD=standard deviation.</p>
                        <p>T2DM= type 2 diabetes mellitus. Total fatalism: the total mean score on the fatalism scale.</p>
                        <p>Pessimism, luck, divine control, internal locus and fatalism are dimensions of the Fatalism Scale.</p>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
            <sec id="sec11">
                <title>Correlation analysis</title>
                <p>According to the correlation analysis, the perceived risk of T2DM was inversely related to fatalism and its dimensions - see 
                    <xref ref-type="table" rid="T3">Table 3</xref>. The level of knowledge was positively correlated with perceived risk of T2DM (r=.178, p&lt;.01). Subsequently, multiple linear regression was performed for perceived risk of T2DM, with fatalism dimensions and knowledge as predictor variables, but only pessimism (&#x03b2;=-.194, p&lt;.01) and divine control (&#x03b2;=-.164, p&lt;.05) were the only predictors, they explained 7.6% of the variance.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>Table 3. </label>
                    <caption>
                        <title>Correlation between fatalism and perceived risk of diabetes mellitus type 2.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variables</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Fatalism</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Pessimism</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Locus</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Luck</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Divine control</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Total fatalism</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">T2DM risk perception</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.160
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.230
                                    <xref ref-type="table-fn" rid="tfn2">**</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.197
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.171
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.210
                                    <xref ref-type="table-fn" rid="tfn2">**</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.257
                                    <xref ref-type="table-fn" rid="tfn2">**</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Knowledge</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">.036</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.055</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.232
                                    <xref ref-type="table-fn" rid="tfn2">**</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.139
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.087</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">-.133
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>Note: T2DM=type 2 diabetes mellitus.</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>
                                    <italic toggle="yes">p&lt;.</italic>05.</p>
                            </fn>
                            <fn id="tfn2">
                                <label>**</label>
                                <p>
                                    <italic toggle="yes">p&lt;.</italic>01.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
        </sec>
        <sec id="sec12" sec-type="discussion">
            <title>Discussion</title>
            <p>The purpose of this research was to analyze the relationship between fatalistic beliefs, knowledge of T2DM risk factors, and the perceived risk of T2DM in Mexican adults during the COVID-19 pandemic. In Mexico there is a large percentage of the adult population at risk of developing T2DM; according to the results of the 2018 National Health and Nutrition Survey most adults aged 20 years or older have a high prevalence of overweight/obesity, as well as being involved in risky behaviors such as alcohol consumption, smoking, sedentary lifestyle, and food insecurity.
                <sup>
                    <xref ref-type="bibr" rid="ref24">24</xref>
                </sup>
            </p>
            <p>In this study, it was identified that the perceived risk of T2DM was high in comparison with other studies in the Asian population.
                <sup>
                    <xref ref-type="bibr" rid="ref25">25</xref>
                </sup> This may be since the most vulnerable population to complications, hospitalization and death from SARS-Cov-2 was people with chronic diseases.
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref26">26</xref>
                </sup> This situation may have generated concern in the population about feeling at risk of developing T2DM and therefore, also feeling vulnerable to the COVID-19 virus. Likewise, even though people with a higher perceived risk of T2DM can make lifestyle changes, it has been reported that during the pandemic, people report an increase in the consumption of alcohol, tobacco and processed foods, emotional problems, and less physical activity.
                <sup>
                    <xref ref-type="bibr" rid="ref27">27</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref28">28</xref>
                </sup>
            </p>
            <p>Our results identified that a quarter of the respondents had above-average scores on fatalistic beliefs. Cultural beliefs are a key element in health care seeking and chronic disease prevention.
                <sup>
                    <xref ref-type="bibr" rid="ref29">29</xref>
                </sup> In several studies it has been reported that people who believe that illness is a result of a supernatural phenomenon do not seek allopathic medical care, but instead seek help from healers or shamans who can help alleviate bad luck, witchcraft or perform prayers.
                <sup>
                    <xref ref-type="bibr" rid="ref30">30</xref>
                </sup>
                <sup>,</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref31">31</xref>
                </sup> This is due firstly because of the distrust they have about the negative beliefs held about treatments such as insulin or peritoneal dialysis, and secondly, because they think that allopathic medicine cannot cure or alleviate diseases that are caused by superhuman forces.</p>
            <p>The level of knowledge was related to a greater perceived risk of T2DM. These results are consistent with previous studies, in which it has been reported that people who have information on the main risk factors and who have family members with a history of T2DM perceive a greater probability of becoming ill.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>
                </sup> In these studies, differences have been found between men and women with the level of knowledge and perceived risk of T2DM. Men have lower level of knowledge about risk factors and lower risk perception but have higher risk of developing T2DM compared to women. Health literacy has been considered as a relevant factor to face health problems and to know that chronic diseases are preventable,
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> but studies in Latin America have indicated that although people have knowledge about T2DM risk factors, they consider that the disease cannot be prevented, that it is the responsibility of the health professional to prevent it and not of oneself.
                <sup>
                    <xref ref-type="bibr" rid="ref32">32</xref>
                </sup>
            </p>
            <p>Finally, we found that people who have high fatalistic beliefs have low perceived risk of developing T2DM. One of the dimensions of fatalistic beliefs that was related to low-risk perception was pessimism. Pessimism has been considered as a negative view, attitude, or idea regarding life events. People with pessimistic ideas have fewer coping strategies, lower self-efficacy, and are carefree
                <sup>
                    <xref ref-type="bibr" rid="ref33">33</xref>
                </sup> considering that positive changes in health cannot be achieved. Thus, people with a pessimistic view have greater problems in making a healthy lifestyle change when they develop chronic diseases.
                <sup>
                    <xref ref-type="bibr" rid="ref34">34</xref>
                </sup> Some authors report that these ideas are since they consider disease as something fatal and that death is inevitable, so that any action they take cannot change it.
                <sup>
                    <xref ref-type="bibr" rid="ref31">31</xref>
                </sup> Another important factor in the perceived risk of T2DM is the belief in divine control. From a religious point of view, beliefs about God are a key element that influences people&#x2019;s behaviors. On the one hand, people with fatalistic religious beliefs allow them to cope better with health problems.
                <sup>
                    <xref ref-type="bibr" rid="ref35">35</xref>
                </sup>
                <sup>&#x2013;</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref37">37</xref>
                </sup>But, on the other hand, they may consider that diseases are tests or punishments from God, and that only God can cure the disease.
                <sup>
                    <xref ref-type="bibr" rid="ref38">38</xref>
                </sup>
                <sup>&#x2013;</sup>
                <sup>
                    <xref ref-type="bibr" rid="ref40">40</xref>
                </sup> This set of beliefs influences people to consider that it does not matter if they make changes in their way of living, because illness cannot be prevented if God does not want it. Also, people may self-perceive themselves to be at lower risk of developing T2DM by self-evaluating themselves without conflict with God.</p>
            <p>The weaknesses of the study include data collection conducted through electronic means and social media on the internet, which resulted in a majority of young adult participants. It is necessary for future studies to collect data through face-to-face interactions in order to include participants from older age groups. The research design was cross-sectional; therefore a cause-and-effect relationship cannot be established. As a result, the findings should be interpreted with caution and extrapolated to similar populations to those in this study.</p>
            <p>On the other hand, the strengths of the study include being one of the first investigations to link fatalistic beliefs with knowledge and perceived risk of T2DM. Additionally, it is a study conducted on a population of young adults from a rural community in Mexico, which highlights the relevance of these beliefs and their implications in identifying knowledge and health risks.</p>
        </sec>
        <sec id="sec13" sec-type="conclusions">
            <title>Conclusions</title>
            <p>In young adults, knowledge increases the perceived risk of T2DM. But fatalistic beliefs decrease knowledge and perceived risk of T2DM. Fatalistic beliefs should be considered a variable that has to be dealt with by health professionals. It is necessary that health professionals consider fatalistic beliefs for the prevention of chronic diseases and improve through educational programs health literacy about the risk factors of T2DM and the benefit of lifestyle, mainly in young adult populations. It is important to provide more education in those who have low knowledge about T2DM risk factors, so that people become more aware of their risk.</p>
        </sec>
    </body>
    <back>
        <sec id="sec16" sec-type="data-availability">
            <title>Data availability</title>
            <sec id="sec17">
                <title>Underlying data</title>
                <p>figshare: Data.sav. 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.22773977.v3">https://doi.org/10.6084/m9.figshare.22773977.v3</ext-link>.
                    <sup>

                        <xref ref-type="bibr" rid="ref41">41</xref>
</sup>
                </p>
                <p>This project contains the raw questionnaire responses.</p>
            </sec>
            <sec id="sec18">
                <title>Extended data</title>
                <p>figshare: Data.sav. 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.22773977.v3">https://doi.org/10.6084/m9.figshare.22773977.v3</ext-link>.
                    <sup>

                        <xref ref-type="bibr" rid="ref41">41</xref>
</sup>
                </p>
                <p>This project contains the demographics questionnaire.</p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
            </sec>
        </sec>
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    </back>
    <sub-article article-type="reviewer-report" id="report335082">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.147307.r335082</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Saidi</surname>
                        <given-names>Sanisah Binti</given-names>
                    </name>
                    <xref ref-type="aff" rid="r335082a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r335082a1">
                    <label>1</label>International Islamic University Malaysia, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>28</day>
                <month>10</month>
                <year>2024</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Saidi SB</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport335082" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.134266.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>Abstract: The problem statement is missing within the abstract. Furthermore, methods of analysis and the total number of samples are missing.&#x00a0;</p>
            <p> Introduction: The concept of fatalism, i.e., the fatalistic perception of diabetes vs. fatalism due to COVID-19, is not clearly discussed. Fatalism might be viewed differently based on these situations, which would affect patients' perceptions of diabetes and the perceived risk that they may have. Furthermore, further discussion on the hypothesised relationship between knowledge about diabetes, fatalistic behaviour related to diabetes and perceived risk of Type 2 diabetes is required to justify the current study.&#x00a0;</p>
            <p> Methods: Did the authors exclude people with type 2 diabetes? Have the samples been infected with and recovered from COVID-19? This might affect their fatalistic beliefs.&#x00a0;</p>
            <p> Findings: Further interpretation of the statistical findings is needed.&#x00a0;</p>
            <p> Discussion: In the first paragraph, the authors do not have to repeat the prevalence of obesity/diabetes but brief the reader about the research objectives and summarize the findings. The primary variable introduced to the reader was fatalism; therefore, it would be more apparent if the authors discussed the findings of fatalism in more detail and provided a clear view to the reader about the fatalistic beliefs of the samples within this study. The influence of culture on fatalistic beliefs was not discussed earlier; therefore, it would be more beneficial if the authors could inform the reader how they have included this aspect within the questionnaires or if it is a new component that has been identified, as it was contained within the discussion.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>I cannot comment. A qualified statistician is required.</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>No</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Diabetes self-care/self-management, fatalism, spiritual care, qualitative research</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment13624-335082">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Guzman</surname>
                            <given-names>Elizabeth</given-names>
                        </name>
                        <aff>Nursing and Obstetrics, University of Guanajuato, Salvatierra, Guanajuato, Mexico</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>25</day>
                    <month>3</month>
                    <year>2025</year>
                </pub-date>
            </front-stub>
            <body>
                <p>We appreciate the valuable comments and suggestions on the manuscript.</p>
                <p> Abstract: we add aim, statistical analyses, sample size and questionnaires used</p>
                <p> Introduction: Fatalism is widespread in risk perception and preventive or risk behaviors, and fatalism is associated with the perception of diabetes risk.</p>
                <p> Methods:&#x00a0;COVID-19 was included as a temporal factor since data collection was carried out during the pandemic.</p>
                <p> Data collection took place at the beginning of the pandemic when the risk of contagion was low, so it was not evaluated.</p>
                <p> Findings:&#x00a0;We added a table for linear regression and its interpretation.</p>
                <p> Discussion:&#x00a0;The first paragraph was deleted</p>
                <p> Some Mexicans believe that illness results from supernatural phenomena, leading them to seek help from healers or shamans rather than allopathic medical care. &#x00a0;These healers are believed to alleviate bad luck, counteract witchcraft, or perform prayers.</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report196704">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.147307.r196704</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Sukkarieh</surname>
                        <given-names>Ola</given-names>
                    </name>
                    <xref ref-type="aff" rid="r196704a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r196704a1">
                    <label>1</label>Hariri School of Nursing, American University of Beirut, Beirut, Beirut Governorate, Lebanon</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>4</day>
                <month>9</month>
                <year>2023</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2023 Sukkarieh O</copyright-statement>
                <copyright-year>2023</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport196704" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.134266.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The purpose of this study was to analyze the relationship between fatalistic beliefs, knowledge of T2DM risk factors, and the perceived risk of T2DM in Mexican adults during the COVID-19 pandemic. The authors could not present clearly the relationship between the three variables of interest. It was hard to follow.</p>
            <p> </p>
            <p> 
                <bold>Abstract:</bold> missing aim, statistical analyses, sample size and questionnaires used</p>
            <p> </p>
            <p> 
                <bold>Manuscript:</bold>
            </p>
            <p> </p>
            <p> 
                <bold>Introduction: </bold>the focus of the introduction is not clear specifically with context of COVID 19. If the main goal is to study fatalism, why is COVID 19 introduced and how does it matter or affect the relationship?</p>
            <p> </p>
            <p> 
                <bold>Methods:</bold>
            </p>
            <p> </p>
            <p> 
                <bold>inclusion criteria:</bold> what about excluding pre-diabetes since it's a major risk factor to develop T2DM and might affect participants' perceptions. what about criteria related to COVID 19 since the time frame seems to be influenced with COVID pandemic.</p>
            <p> </p>
            <p> 
                <bold>Results:</bold>
            </p>
            <p> </p>
            <p> Why were the scores categorized instead of being used as continuous variables when the latter yields stronger data analyses?</p>
            <p> </p>
            <p> Descriptive data can be combined in one table for ease of following (T1and T2)</p>
            <p> </p>
            <p> There needs to be T4 for multiple linear regression.</p>
            <p> </p>
            <p> 
                <bold>Discussion:</bold> 
                <list list-type="order">
                    <list-item>
                        <p>needs to start with brief summary of the findings</p>
                    </list-item>
                    <list-item>
                        <p>in 1st paragraph, authors cannot introduce new concepts of risky behaviors when it is out of the scope of the paper.&#x00a0;</p>
                    </list-item>
                    <list-item>
                        <p>presentation of findings are not aligned with T3, i.e. there is no reflection on negative or positive existing relationships.</p>
                    </list-item>
                    <list-item>
                        <p>Additionally, the variables are not well identified in the discussion as to what is the outcome of interest which is according to the methods section: Dependent variable: Perceived risk of Type 2 Diabetes Mellitus.</p>
                    </list-item>
                    <list-item>
                        <p>regression analysis is missed from the discussion.&#x00a0;</p>
                    </list-item>
                </list> 
                <bold>Weakness: </bold>need to acknowledge limitations of self-report which affects biases in responses and lack of generalizability due to research design..</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>No</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>No</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>No</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>No</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>My areas of expertise is diabetes self-management, fatalism in diabetes, social determinants of health</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment13623-196704">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Guzman</surname>
                            <given-names>Elizabeth</given-names>
                        </name>
                        <aff>Nursing and Obstetrics, University of Guanajuato, Salvatierra, Guanajuato, Mexico</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>25</day>
                    <month>3</month>
                    <year>2025</year>
                </pub-date>
            </front-stub>
            <body>
                <p>We appreciate the valuable comments and suggestions on the manuscript.</p>
                <p> Abstract: We added the aim, statistical analyses, sample size and questionnaires used.</p>
                <p> 
                    <bold>Introduction:&#x00a0;</bold>COVID-19 was added as a temporal factor since data collection was carried out during the pandemic.</p>
                <p> 
                    <bold>Results:&#x00a0;</bold>The scores categorized for sociodemographic data were used for descriptive statistics; however, continuous variables were used for inferential analysis.</p>
                <p> Table 1 is extensive, which limits the possibility of adding more information on a single page.</p>
                <p> An additional table was included for multiple linear regression.</p>
                <p> 
                    <bold>Discussion:</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>A summary of the findings is written.</p>
                        </list-item>
                        <list-item>
                            <p>Some information has been deleted.</p>
                        </list-item>
                        <list-item>
                            <p>Adjustments have been made to the table, and the results are presented according to the main objective of the study. Information on the direction of the relationship between fatalism and risk perception (dependent variable) has been added.</p>
                        </list-item>
                        <list-item>
                            <p>A negative relationship was found between fatalism and risk perception for diabetes mellitus. This contrasts with a recent sample of university students, which showed that fatalistic beliefs are negatively related to risk behaviors for diabetes mellitus. These findings also align with the results of another study conducted on health professionals, which demonstrated that fatalistic beliefs negatively affect perceptions of occupational health.</p>
                        </list-item>
                        <list-item>
                            <p>In the sixth paragraph, we discuss the findings of the regression analysis.</p>
                        </list-item>
                    </list> 
                    <bold>Weakness:&#x00a0;</bold>
                </p>
                <p> Our findings are only generalizable to a rural community in Mexico. However, future studies are recommended in diverse cultural settings to replicate our findings and further explore the influence of fatalistic beliefs and perceived risk of T2DM. Additionally, qualitative studies are needed to provide a deeper understanding of fatalistic beliefs.</p>
            </body>
        </sub-article>
    </sub-article>
</article>
