<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.157561.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Understanding decision making for the use of atraumatic restorative approach based on non-clinical factors by Indian pedodontists - a conjoint analysis.</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 2 approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Nadar</surname>
                        <given-names>Bhuvaneshwari</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-9267-9297</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>GV</surname>
                        <given-names>Usha</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Almalki</surname>
                        <given-names>Sultan A.</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3369-9925</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Gowdar</surname>
                        <given-names>Inderjit M.</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3920-8082</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Public Health Dentistry, TPCT's Terna Dental College, Nerul, Navi Mumbai, Maharashtra, 400706, India</aff>
                <aff id="a2">
                    <label>2</label>Public Health Dentistry, Bapuji Dental College and Hospital, Davangere, KARNATAKA, 577004, India</aff>
                <aff id="a3">
                    <label>3</label>Preventive Dental Sciences, College of Dentistry Prince Sattam bin Abdul Aziz University, Al-kharj, KSA, Saudi Arabia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:bhuvana15689@gmail.com">bhuvana15689@gmail.com</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>21</day>
                <month>11</month>
                <year>2024</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2024</year>
            </pub-date>
            <volume>13</volume>
            <elocation-id>1401</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>8</day>
                    <month>11</month>
                    <year>2024</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Nadar B et al.</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/13-1401/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Atraumatic Restorative Treatment (ART) approach is considered as one of the minimally invasive interventions. The success of restoration depends on various clinical factors like material, patient and operator factor. Conjoint analysis is a technique for measuring individual&#x2019;s preference structures via systematical variations of products attributes in an experimental design.</p>
                </sec>
                <sec>
                    <title>Aim</title>
                    <p>Assess Pedodontists&#x2019; perception of non-clinical factors and investigate influence of child&#x2019;s age, level of cooperation and vulnerability status on their decisions to perform Atraumatic Restorative Approach (ART) approach using hypothetical patient scenario&#x2019;s and conjoint design.</p>
                </sec>
                <sec>
                    <title>Materials and methods</title>
                    <p>A cross-sectional exploratory survey using a web-based questionnaire was performed among Pedodontists registered as life members under Indian Association of Pedodontic and Preventive Dentistry. Self-designed structured scenario-based questionnaire was prepared and validated. Three non-clinical factors Age of child, Cooperation level and Vulnerability status were considered. Using orthogonal design, SPSS software nine profiles were created randomly along with two holdouts. Final study proforma consisted of three sections with description of eleven clinical scenarios. It was administered to participants using Google forms. Using SPSS conjoint software relative utilities for each factor on decision for using ART was estimated.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>Four hundred and thirty-two pedodontists had completed the survey (35.9%). Pedodontists considered vulnerability status of the child as the most important factor for their decision to use ART treatment. For the vulnerability status, the factor vulnerable had the greatest utility (-0.364) compared to non-vulnerable factor (0.364). For cooperation level, factor uncooperative had greater utility (-0.343), as compared to moderately cooperative (0.066) and uncooperative (0.277). For the age factor, the age of 4 years had the greatest utility (-0.175) compared with age 6 (-0.013) and age 12 (0.19).</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>The most preferred scenario by pedodontists to consider ART as treatment of choice was child belonging to vulnerable section, being very young and uncooperative.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>atraumatic restorative treatment</kwd>
                <kwd>conjoint analysis</kwd>
                <kwd>dillmans technique</kwd>
                <kwd>response rate</kwd>
                <kwd>decision making</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1">
                    <funding-source>Prince Sattam Abdul Aziz University, Al-kharj</funding-source>
                    <award-id>PSAU/2024/01/99528</award-id>
                </award-group>
                <funding-statement>The authors extend their appreciation to Prince Sattam bin Abdulaziz University for funding this research work through project number (PSAU/2024/01/99528)</funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec6" sec-type="intro">
            <title>Introduction</title>
            <p>Minimum intervention dentistry can be defined as a philosophy of professional care concerned with the first occurrence, earliest detection and possible cure of diseases on micro levels, followed by minimally invasive and patient friendly treatment to repair irreversible damage caused by such disease.
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup> Atraumatic Restorative Treatment (ART) is a key technique in this approach, has gained significant interest recently, especially in addressing dental care access challenges.
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> Originally developed for use in developing countries with limited resources, ART has proven effective in treating primary dentition, achieving high success rates.
                <sup>
                    <xref ref-type="bibr" rid="ref3">3</xref>
                </sup> Its adoption in developed countries has primarily focused on managing severe early childhood caries. ART utilizes fluoride-releasing glass ionomer materials, which help control caries progression while providing a patient-friendly, minimally invasive approach. This method not only facilitates care in resource-limited settings but also supports preventive strategies in more affluent areas, highlighting its versatility and effectiveness in managing progressive dental caries.
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup>
            </p>
            <p>A meta-analysis conducted in 2021 evaluated the success rates of Atraumatic Restorative Treatment (ART) in both primary and permanent dentitions. The findings indicated impressive success rates at the 12-month follow-up mark: 71% for ART restorations on primary teeth and 96% for those on permanent teeth, without influenced by setting. These results underscore ART&#x2019;s effectiveness as a reliable treatment option, reinforcing its role in minimally invasive dentistry, especially for managing caries in diverse patient populations.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup>
            </p>
            <p>The success of dental restorations, including Atraumatic Restorative treatment (ART) is influenced by a variety of clinical factors. Among these, the operator&#x2019;s decisions are crucial. Key operator factors include the diagnostic methods used, the dentist&#x2019;s preferences and beliefs about restoration longevity and effectiveness, as well as their skills and experience.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>
                </sup> The choice of materials and the nature of the intervention also play significant roles. For example, a dentist&#x2019;s restorative decisions may depend on the patient&#x2019;s age, behavioral compliance, caries risk, and socioeconomic background.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>
                </sup> These factors shape how the dentist approaches treatment, ultimately impacting the overall success of the restoration. Therefore, a comprehensive understanding of both clinical and patient-specific variables is essential for optimizing treatment outcomes in dentistry.
                <sup>
                    <xref ref-type="bibr" rid="ref8">8</xref>
                </sup>
            </p>
            <p>One of the most common methods for assessing dental restorative treatment decisions is through survey research. In these surveys, respondents answer direct questions about their preferences and the importance of various factors that influencing their choices of dental procedures. However, this method typically evaluates individual factors in isolation and does not capture the complexity of &#x201c;derived decisions,&#x201d; which consider multiple factors simultaneously.
                <sup>
                    <xref ref-type="bibr" rid="ref9">9</xref>
                </sup> This limitation can affect the validity of the data and insights derived from such surveys, making it essential to consider alternative methods or complementary approaches to gain a more comprehensive understanding of decision-making in dental restorative treatments.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup>
            </p>
            <p>In the early 1970s, Green and Rao introduced conjoint measurement to marketing research to better understand and predict buyer behavior.
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup> The term &#x201c;conjoint&#x201d; reflects the concept that multiple factors can be evaluated together,
                <sup>
                    <xref ref-type="bibr" rid="ref12">12</xref>
                </sup> allowing individuals to make choices among different hypothetical products or treatment scenarios rather than assessing each characteristic in isolation. Recently, the popularity of conjoint analysis has grown in health outcomes research.
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> Conjoint analysis has seen limited application in dental research, but its potential is being recognized.
                <sup>
                    <xref ref-type="bibr" rid="ref9">9</xref>,
                    <xref ref-type="bibr" rid="ref10">10</xref>,
                    <xref ref-type="bibr" rid="ref14">14</xref>,
                    <xref ref-type="bibr" rid="ref15">15</xref>
                </sup> One notable study utilized conjoint analysis to evaluate dentists&#x2019; decisions regarding implant treatment based on various patient characteristics.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> This research revealed differences between dentists&#x2019; stated preferences and their derived decisions, suggesting that conjoint analysis can more accurately reflect actual decision-making processes by requiring respondents to make trade-offs in a choice context.</p>
            <p>Despite its advantages, studies examining dentists&#x2019; use of specific techniques and the factors influencing their decisions remain relatively scarce. As the field continues to evolve, applying conjoint analysis could provide deeper insights into how various attributes impact treatment decisions, ultimately leading to more informed and patient-centered care in dentistry.</p>
            <p>Dentist&#x2019;s clinical decision making regarding restorative interventions for the treatment of caries vary significantly.
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> The ART approach, has been recognized as an economical and effective method for managing carious lesions, in vulnerable population.
                <sup>
                    <xref ref-type="bibr" rid="ref17">17</xref>
                </sup> Decisions to use ART often depend on social and environmental factors, including a child&#x2019;s age, socioeconomic status, and level of cooperation.
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>
                </sup>
            </p>
            <p>Despite ART&#x2019;s relevance, there has been no research assessing the perceptions of Indian pedodontists. This study aims to explore how these non-clinical factors influence pedodontists&#x2019; willingness to adopt the ART approach, using hypothetical patient scenarios and a conjoint design. The central research question investigates whether differences exist in clinical decision-making among pedodontists regarding ART while considering these non-clinical factors?</p>
        </sec>
        <sec id="sec7" sec-type="methods">
            <title>Methods</title>
            <p>The study was designed, analyzed, and interpreted according to the Conjoint Analysis applications in the health checklist.
                <sup>
                    <xref ref-type="bibr" rid="ref19">19</xref>
                </sup>
            </p>
            <sec id="sec8">
                <title>Participants</title>
                <p>A cross-sectional exploratory survey was conducted among pedodontists using a web-based questionnaire. All the Pedodontists registered as life members under the Indian Association of Pedodontic and Preventive Dentistry and who were willing to participate were included.</p>
            </sec>
            <sec id="sec9">
                <title>Instrument</title>
                <p>The first stage in the design of a conjoint study is to choose attributes and assign levels.
                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>

                                <underline>

                                    <italic toggle="yes">Defining attributes</italic>
</underline>
                            </p>
                            <p>An attribute is a characteristic of a product (e.g., color), made up of various levels (there must be at least two for each attribute) or degrees of that characteristic (e.g., red, yellow, blue).
                                <sup>
                                    <xref ref-type="bibr" rid="ref20">20</xref>
                                </sup> Conjoint analysis elicits preferences for a decision over the range of attributes and levels that define the hypothetical scenarios was used in questions. The three non-clinical factors or attributes selected for the present study were patient age, level of cooperation, and vulnerability status. These were selected based on a literature review and expert opinions. These attributes were refined through consultations with experts from the Department of Pedodontics and Public Health Dentistry. The modified attributes chosen were found to be meaningful to test and relevant to understand their interplay for clinical decisions by dentists.</p>
                        </list-item>
                        <list-item>
                            <label>2.</label>
                            <p>

                                <underline>

                                    <italic toggle="yes">Assigning levels</italic>
</underline>
                            </p>
                            <p>For the chosen attributes, levels were assigned, providing a realistic profile/scenario capable of being traded.
                                <sup>
                                    <xref ref-type="bibr" rid="ref14">14</xref>
                                </sup> Attribute levels were identified after a literature review and discussion with experts. For age four, six and 12 years, which coincide with the three important stages, that is, primary, mixed dentition, and 12 years, the global indicator age group was selected. For the child cooperation level, Frankl&#x2019;s behavior rating scale, the first and second categories (definitively negative and negative) were clubbed together and considered as uncooperative; the third category positive was modified as moderately cooperative and the fourth category definitively positive was modified as cooperative for convenience. The third factor, vulnerability status, was classified as vulnerable or non-vulnerable. Children who attended public schools, orphans, or were either physically or mentally challenged were considered vulnerable. Attending private schools, physically and mentally healthy, and living with parents as non-vulnerable.</p>
                        </list-item>
                    </list>
                </p>
                <p>Considering the three non-clinical factors, the possible permutation combination of the scenarios/profiles was 18. According to literature, all the Profiles should be included in the study, but by doing so it can cause fatigue and boredom set in.
                    <sup>
                        <xref ref-type="bibr" rid="ref14">14</xref>
                    </sup> Therefore, by using Fractional Factorial Design the number of paired comparisons were reduced to the smallest number necessary for efficient estimation of utility weights.
                    <sup>
                        <xref ref-type="bibr" rid="ref21">21</xref>
                    </sup> Using orthogonal design in SPSS software, half fraction (nine Profiles) were created randomly. The software algorithm was programmed to extrapolate the total utility values for all possible patient scenarios for each study participant, although a subset of scenarios was used.</p>
                <p>The self-designed structured web-based questionnaire had three sections: a) nine conjoint questions, with the definition of ART, and a detailed explanation regarding the clinical presentation of the carious lesion in all scenarios. Clinical conditions were fixed for all scenarios with carious lesions involving the primary or permanent molar, with the depth of the lesion within dentin and no pulpal involvement clinically or radiographically. A description regarding the three non-clinical factors that varied in all scenarios are described. Pedodontists were requested to rate how likely they were to use ART on a 5 &#x2013; point likert scale, ranging from 5 (very unlikely to use ART) to 1 (very likely to use ART). b) Two questions focused on whether pedodontists consider ART to be definitive or interim treatment and why, as well as a question asking where they learned about ART. c) The last three questions on demographic and practice characteristics. The questionnaire was pretested for content validity by two faculty members, each from the Department of Public Health Dentistry and the Department of Pedodontics. The CVI score is 0.88, suggesting good content validity.
                    <sup>
                        <xref ref-type="bibr" rid="ref22">22</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec10">
                <title>Administration of the questionnaire and data collection</title>
                <p>A web-based survey questionnaire with the help of Google Forms was administered to all pedodontists registered as life members. The questionnaire was in the form of a booklet with multiple sections containing the covering letter, its usefulness and importance of the respondent response, online consent form, the survey questions, and the thank you note with participants&#x2019; suggestions regarding the study and their opinions. An invitation email was sent to all participants to 2-3 days prior to the actual email of the survey. Personalized emails that included a link to the web survey. Three reminder mails were sent after the first, fourth, and seventh week to improve the response rate. The remaining mails included a covering letter and a replacement questionnaire, emphasizing the respondent&#x2019;s importance and explanation of the identification number and how confidentiality is protected and a thank you message.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec11">
                <title>Analysis</title>
                <p>SPSS conjoint software [IBM Corp. in Armonk, NY] (
                    <ext-link ext-link-type="uri" xlink:href="https://www.ibm.com/spss">https://www.ibm.com/spss</ext-link>) was used to estimate the relative weights (utilities) for each level of the presented factors in the decision to use ART. Linear regression was used to generate the utility scores for each attribute level.</p>
            </sec>
        </sec>
        <sec id="sec12" sec-type="results">
            <title>Results</title>
            <p>In the present survey, 432 pedodontists have responded, with a response rate of 35.9% (
                <xref ref-type="fig" rid="f1">Figure 1</xref>). They were predominantly female 62%. About 32% were into academics and private practitioners, 28% private practitioners, 30% postgraduate students, and 10% were only academics. More than half of the respondents (62%) reported ART as interim treatment and 38% as definitive for the given scenarios. Factors included depth of lesion (53%), caries risk (24%), personal skill (4%), time constraints (5%), number of surfaces, and other reasons (7%) (see 
                <xref ref-type="fig" rid="f2">Figure 2</xref>). Pedodontists reported, they had learned ART during undergraduate courses (45.3%), postgraduation (24.7%), textbooks and articles (23.3%), and continuing dental education programs and conferences (6.7%).</p>
            <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                <label>Figure 1. </label>
                <caption>
                    <title>Flowchart of the study.</title>
                </caption>
                <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/173021/df58bf6b-1e53-4b28-a748-aeb0ceb13ce9_figure1.gif"/>
            </fig>
            <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                <label>Figure 2. </label>
                <caption>
                    <title>Factors influencing the definitive treatment selection for art approach.</title>
                </caption>
                <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/173021/df58bf6b-1e53-4b28-a748-aeb0ceb13ce9_figure2.gif"/>
            </fig>
            <p>The utility value for each attribute and level was computed. For the attribute cooperation, vulnerability status and age, levels uncooperative, being vulnerable, and four years had the lowest utility values of-0.242, -0.148, and -0.117, respectively (
                <xref ref-type="fig" rid="f3">Figure 3</xref>). As a score of one was given for option very likely and five for option very unlikely, the attribute levels with the least value suggest the ones with a high preference for treatment decision. The total utility for different combinations of attribute levels is calculated using an additive linear regression equation (
                <xref ref-type="table" rid="T1">
Table 1</xref>). The scenario being uncooperative, belonging to vulnerable section and four years of age was most preferred for ART (2.292). Being moderately cooperative, non-vulnerable, and 12 years old was the least preferred scenario (3.114).</p>
            <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                <label>Figure 3. </label>
                <caption>
                    <title>Bar graph depicting the utility value for each attribute levels.</title>
                </caption>
                <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/173021/df58bf6b-1e53-4b28-a748-aeb0ceb13ce9_figure3.gif"/>
            </fig>
            <table-wrap id="T1" orientation="portrait" position="float">
                <label>
Table 1. </label>
                <caption>
                    <title>Preference (utility) scores for the nine case scenarios presented in the conjoint analysis questionnaire.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top">Scenario</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Age</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Cooperation level</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Vulnerability status</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Utility score</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
Ranking</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 1</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Non-vulnerable
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3.031</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">8</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 2</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Moderately Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.683</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 3</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.978</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 4</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Uncooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.292</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 5</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Uncooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.535</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 6</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.843</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 7</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Moderately Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Non-vulnerable
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3.114</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">9</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 8</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Uncooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Non-vulnerable
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.696</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Scenario 9</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Moderately Cooperative</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Vulnerable</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.575</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                        </tr>
                    </tbody>
                </table>
            </table-wrap>
        </sec>
        <sec id="sec13" sec-type="discussion">
            <title>Discussion</title>
            <p>To our knowledge, this is the first study in India to use a clinical scenario-based and rigorous statistical approach to measure pedodontists&#x2019; perception (relative utilities) for decision making for ART. We found that pedodontists value behavior and vulnerability status in decision-making when compared to the age of the child. An uncooperative child belonging to the vulnerable population and being young was the most preferred scenario in clinical decision-making for ART by Pedodontists. The depth of the lesion and individual caries risk were the most important factors reported while considering ART as a definitive treatment.</p>
            <p>The use of conjoint design demonstrated the importance of patient factor vulnerability status in clinical restorative treatment decisions for children, in addition to their age and cooperation level. Using conjoint analysis, the relative importance of different factors, trade-offs pedodontists make between these factors, and utility or importance for combinations of test factors were possible. This is because it enables the measurement of psychological, real, or hidden factors in professional behavior (decision-making).
                <sup>
                    <xref ref-type="bibr" rid="ref24">24</xref>
                </sup>
            </p>
            <p>In the present study, ART was considered an interim treatment by 62% pedodontists for the presented scenarios, similar finding was observed in a previous study where 82% American pedodontists stated the same.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> The views are opposing to that of the current literature wherein ART is viewed globally as a definitive treatment, particularly in certain populations that do not have access to more traditional restorative treatment.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> The World Health Organization and International Dental Federation recognize ART as part of the basic package of oral care for all communities around the world.
                <sup>
                    <xref ref-type="bibr" rid="ref25">25</xref>
                </sup>
            </p>
            <p>A pre-invitation mail and three attempts were made to contact all the registered pedodontists (1200) through online electronic mail to improve response rates, as stated by Dillman.
                <sup>
                    <xref ref-type="bibr" rid="ref23">23</xref>
                </sup> We could achieve a response rate of 35.9%. With a reported average response rate of 24.8% for email surveys
                <sup>
                    <xref ref-type="bibr" rid="ref26">26</xref>
                </sup> we achieved a better response. Similar response rates were found in other published surveys by Janakiram C (30.9%) and Kaul R (38.3%).
                <sup>
                    <xref ref-type="bibr" rid="ref27">27</xref>,
                    <xref ref-type="bibr" rid="ref28">28</xref>
                </sup> Despite having active email accounts, online surveys were not acceptable to many.
                <sup>
                    <xref ref-type="bibr" rid="ref27">27</xref>
                </sup> In our study about 432 pedodontists participated. Al-Omari B et al
                <sup>
                    <xref ref-type="bibr" rid="ref20">20</xref>
                </sup> recommended a sample size of 300 for conjoint study. Therefore, the study sample size was larger than the recommended sample size for the conjoint analysis.</p>
            <p>Controlled clinical factors independently drive the decision to administer ART. It enabled assessment of the pedodontists&#x2019; perception and their relative importance on the other three non-clinical factors in clinical decision-making. The clinical presentation was fixed in accordance with recent evidence showing that ART single-surface restorations using high-viscosity GIC had a high survival rate in both primary and permanent teeth, comparable to that of traditional amalgam restorations.
                <sup>
                    <xref ref-type="bibr" rid="ref29">29</xref>
                </sup> Moreover, as ART restorations are both minimally invasive and caries-protective when compared to other traditional restorative methods, it can be considered as a treatment of choice for single-surface caries lesions.
                <sup>
                    <xref ref-type="bibr" rid="ref30">30</xref>
                </sup>
            </p>
            <p>In the present study, ART was more likely to be preferred by young children who were uncooperative and vulnerable. These findings are consistent with the endorsement of the World Health Organization and the International Association for Dental Research. According to the WHO, ART may be used to restore and prevent caries in young patients, uncooperative patients, or patients with special health care needs
                <sup>
                    <xref ref-type="bibr" rid="ref31">31</xref>
                </sup> and also where traditional cavity preparation and/or placement of traditional dental restorations are not feasible.
                <sup>
                    <xref ref-type="bibr" rid="ref31">31</xref>
                </sup> As stated by Jo E Frenken, ART is the best treatment for very young children with behavioral problems.
                <sup>
                    <xref ref-type="bibr" rid="ref32">32</xref>
                </sup> The results are in accordance with the study by Kateeb et al., where the pediatric dentist preferred ART for uncooperative children.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> Interestingly, in the present study, young age had less utility value and the last preferred factor among the three non-clinical factors. In contrast, young age was the second most preferred factor for ART treatment in a study by Kateeb et al.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup>
            </p>
            <p>The vulnerability status factor was considered to identify the relative importance of pedodontists in clinical decision-making. The results showed that the vulnerability status of the child was the second most important factor stated by study participants. Even though Atraumatic Restorative Treatment (ART) is considered an economical and effective method for preventing and controlling carious lesion development in vulnerable populations.
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>,
                    <xref ref-type="bibr" rid="ref33">33</xref>
                </sup> The recent evidence stated higher survival rates comparable to traditional restorations and being safe to use.
                <sup>
                    <xref ref-type="bibr" rid="ref33">33</xref>
                </sup> ART can be considered to be a cornerstone of minimal intervention caries management in combination with prevention and minimal invasion.
                <sup>
                    <xref ref-type="bibr" rid="ref30">30</xref>
                </sup> Therefore, thorough and careful performance of all the technical steps can lead to successful long-lasting restorations. Further studies on atraumatic restorative treatment are needed to validate its effectiveness and acceptability.</p>
            <p>A study by Molina et al. showed a higher one-year survival rate for all ART restorations compared to conventional restorations in adults with intellectual disability.
                <sup>
                    <xref ref-type="bibr" rid="ref34">34</xref>
                </sup> The strengths of the study were the joint design, which allowed an unbiased precise preference estimate, thereby reducing confounding bias. Anonymous mailed questionnaires reduced interviewer bias and social desirability bias. The survey had a few scenarios and questions, thereby reducing response fatigue. A subset of potential patient scenarios was randomly selected and presented to participants using an orthogonal fractional factorial design. The software algorithm was programmed to extrapolate the total utility values for all possible patient scenarios for each participant. It generates a random sequence of scenarios, avoiding learning and primacy biases.</p>
            <p>The hypothetical nature of questions, time consumption, and reported behavior may not be the actual behavior, which were the limitations of the study. Further studies are required to confirm the hypotheses derived from this study. Dental professionals should be encouraged to adopt new, less invasive, and simple restorative techniques, such as ART. Pedodontists can be sensitized to the effectiveness of ART, irrespective of children&#x2019;s cooperation, vulnerability status, and age. This can be emphasized by incorporation into the early stages of clinical training through CDE and CME programs.</p>
        </sec>
        <sec id="sec14" sec-type="conclusion">
            <title>Conclusion</title>
            <p>The most preferred scenario by pedodontists to consider ART as the treatment of choice was an uncooperative child belonging to a vulnerable section and being very young.</p>
        </sec>
        <sec id="sec15">
            <title>Ethics and consent</title>
            <p>The study protocol was approved by the Institutional Review Board of Bapuji Dental College and Hospital, under approval number BDC/383/2017-18 dated 24/11/2017. The Committee on Research Ethics adhered to international guidelines for human subject protection, including the Declaration of Helsinki, The Belmont Report, and CIOMS guidelines. All participants provided voluntary written informed consent using an electronic consent system before accessing the online survey. The consent form clearly outlined the survey&#x2019;s purpose, the estimated time required to complete the questionnaire, and used simple, understandable language. Participants were informed that they could withdraw from the survey at any time, and that their personal information would be kept confidential.</p>
        </sec>
    </body>
    <back>
        <sec id="sec18" sec-type="data-availability">
            <title>Data availability statement</title>
            <sec id="sec19">
                <title>Underlying data</title>
                <p>Figshare &#x2013; Understanding decision making for use of Atraumatic Restorative Approach based on non-clinical factors by Indian Pedodontists - A conjoint analysis, 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.27188796">https://doi.org/10.6084/m9.figshare.27188796</ext-link>.
                    <sup>
                        <xref ref-type="bibr" rid="ref35">35</xref>
                    </sup>
                </p>
                <p>This project contains following underlying data:
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Conjoint study-data.xlsx</p>
                        </list-item>
                    </list>
                </p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">Creative Commons Zero &#x201c;No rights reserved&#x201d; data waiver</ext-link> (CC BY 4.0 Public domain dedication).
                    <sup>
                        <xref ref-type="bibr" rid="ref35">35</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec20">
                <title>Extended data</title>
                <p>Figshare - Understanding decision making for the use of atraumatic restorative approach based on non-clinical factors by Indian pedodontists - a conjoint analysis (Questionnaire), 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.27283890">https://doi.org/10.6084/m9.figshare.27283890</ext-link>.
                    <sup>
                        <xref ref-type="bibr" rid="ref36">36</xref>
                    </sup>
                </p>
                <p>This project contains following extended data
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Survey questionnaire, participant information and consent form.docx</p>
                        </list-item>
                    </list>
                </p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">Creative Commons Zero &#x201c;No rights reserved&#x201d; data waiver</ext-link> (CC BY 4.0 Public domain dedication).</p>
            </sec>
        </sec>
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    </back>
    <sub-article article-type="reviewer-report" id="report343457">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.173021.r343457</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Gangadharappa</surname>
                        <given-names>Dr Praveen</given-names>
                    </name>
                    <xref ref-type="aff" rid="r343457a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-6571-1941</uri>
                </contrib>
                <aff id="r343457a1">
                    <label>1</label>Jazan University, Jazan, Saudi Arabia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>3</day>
                <month>12</month>
                <year>2024</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Gangadharappa DP</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport343457" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.157561.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>
                <bold>Title and Abstract:</bold> The title and abstract effectively summarize the key aspects of the study, giving a clear overview of its scope and objectives. 
                <bold>Introduction:</bold> The introduction presents a well-structured and logical framework, supported by relevant citations. It successfully establishes the background and context for the study, highlighting the need for the research in the field.</p>
            <p> 
                <bold>Need for the Study:</bold> The rationale for the study is strongly justified, with a solid scientific background that highlights its significance. The research addresses an important gap in the existing literature, underlining the contribution it makes to the field. &#x2022; 
                <bold>Methodology:</bold> The methodology is clearly described and easily replicable. The research design, sampling methods, and procedures are well-detailed. The statistical analysis is appropriate and robust, ensuring that the findings are valid and reliable.</p>
            <p> 
                <bold>Tables and Figures</bold>: The tables and figures are relevant and well-aligned with the objectives of the study. They help in presenting the data clearly and support the interpretation of the results.</p>
            <p> 
                <bold>Discussion:</bold> The discussion is meaningful and provides a thorough interpretation of the results. The comparison with previous studies is appropriate and helps to contextualize the findings within the broader scientific landscape.&#x00a0;</p>
            <p> 
                <bold>Conclusion:</bold> The conclusion is consistent with the study's findings. It clearly summarizes the key outcomes and provides insights that are logically derived from the research.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>I cannot comment. A qualified statistician is required.</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>IMPLANTS, IMPRESSIONS, COMPLETE DENTURE PROSTHODONTICS,</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report343455">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.173021.r343455</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>KV</surname>
                        <given-names>Dr Suresh</given-names>
                    </name>
                    <xref ref-type="aff" rid="r343455a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r343455a1">
                    <label>1</label>SEGi University Kota Damansara, Petaling Jaya, Selangor, Malaysia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>2</day>
                <month>12</month>
                <year>2024</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 KV DS</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport343455" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.157561.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>Thank you for this opportunity&#x00a0;&#x00a0;</p>
            <p> The manuscript is well-structured and adheres to the STROBE guidelines, ensuring clarity and transparency in reporting. Both the title and abstract are informative, providing a concise summary of the study&#x2019;s aims, methods, and key findings. The introduction effectively highlights the need for the study, clearly stating the research aim and objectives. The background provided justifies the significance of the study in the current scientific context. The authors have thoroughly explained the validation process for the data collection instrument, ensuring reliability and credibility. The study design is well-described, and the sample size has been scientifically estimated using an appropriate formula. The depth of detail in the method of data collection facilitates replication, making the research transparent and reproducible. The consent process is described in detail, ensuring adherence to ethical standards in research. The statistical methods used for analysis are clearly specified and are appropriate for the type of data obtained. This ensures the robustness of the results and provides confidence in the conclusions drawn. The results are clearly presented in well-organized tables, with comprehensive information about the characteristics of the study participants. This allows for a detailed understanding of the study's sample and its generalizability. The discussion provides a concise summary of the key results and interprets them within the context of previous literature. The authors have appropriately cited studies with similar findings, providing a balanced and informed discussion. The manuscript includes useful recommendations for conducting similar research in the future, based on the study's findings and limitations. References are following the journal&#x2019;s guidelines.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>TMDs, Orofacial pain, CBCT</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
</article>
