<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="systematic-review" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.151869.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Systematic Review</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Leisure-Based Interventions in Adults with Schizophrenia: A Scoping Review</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 1 approved with reservations]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Nishad</surname>
                        <given-names>Amar</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-5761-1721</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Mysore Nagaraj</surname>
                        <given-names>Anil Kumar</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-4436-9761</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>R Rao</surname>
                        <given-names>Chythra</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-4016-2683</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>P</surname>
                        <given-names>Keshavaram</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0009-0007-6095-2432</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Rajpaul</surname>
                        <given-names>Priyanka</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0009-0008-0143-005X</uri>
                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Department of Occupational Therapy, Manipal College of Health Professions, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India</aff>
                <aff id="a2">
                    <label>2</label>Department of Psychiatry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India</aff>
                <aff id="a3">
                    <label>3</label>Department of Community Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India</aff>
                <aff id="a4">
                    <label>4</label>Occupational Therapy, Sukoon Health, Gurugram, New Delhi, 110048, India</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:anilkumar.nagaraj@manipal.edu">anilkumar.nagaraj@manipal.edu</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>27</day>
                <month>6</month>
                <year>2024</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2024</year>
            </pub-date>
            <volume>13</volume>
            <elocation-id>698</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>17</day>
                    <month>6</month>
                    <year>2024</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Nishad A et al.</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/13-698/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Schizophrenia is a severe mental illness characterized by psychosis, apathy, social withdrawal, and cognitive impairment, which results in impaired functioning in work, school, parenting, self-care, independent living, interpersonal relationships, and leisure time.</p>
                </sec>
                <sec>
                    <title>Method</title>
                    <p>A systematic search was conducted using Arksey and O&#x2019;Malley&#x2019;s framework with studies published on leisure-based intervention from January 1990 to December 2023.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>The review included 11 articles in the study. In total two studies were pilot interventional study, one randomized controlled study, one case-control, one retrospective study, three were cross sectional, one was cross sectional longitudinal study and two were qualitative in nature. Studies used different types of leisure activities like cooking group, discussions, board games, arts and craft, painting, beading, sewing, clay work, paper craft, etc were used as an intervention. Qualitative studies found that individuals with schizophrenia spent less time in social and leisure activities and more time relaxing and doing nothing.</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>The study highlights the need to conduct further research on leisure-based interventions using various study designs like randomized controlled trials and mixed methods to understand its effectiveness among individuals with schizophrenia.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Leisure-based interventions</kwd>
                <kwd>schizophrenia</kwd>
                <kwd>Adults</kwd>
                <kwd>Recreation</kwd>
                <kwd>Scoping review</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>Introduction</title>
            <p>Schizophrenia is a severe mental disorder characterized by psychosis, apathy, social withdrawal, and cognitive impairment, which results in impaired functioning in work, school, parenting, self-care, independent living, interpersonal relationships, and leisure time (
                <xref ref-type="bibr" rid="ref6">Geller, 1992</xref>). Approximately 24 million individuals worldwide, or 1 in 300, are affected by schizophrenia. In adulthood, the corresponding rate is 1 in 222. The most common times for onset are in late teens and the twenties, and in men it happens earlier than in women (
                <xref ref-type="bibr" rid="ref22">World Health Organization, 2022</xref>). One of the main mental health disorders contributing to the global disease burden is schizophrenia, that also affects social functioning (
                <xref ref-type="bibr" rid="ref23">World Health Organization, 2012</xref>). People with schizophrenia have both internal and environmental obstacles to engaging in leisure activities, such as side effects from medicine, cultural stigma, family dynamics, and cultural norms (
                <xref ref-type="bibr" rid="ref16">Rezaie et al., 2017</xref>).</p>
            <p>Leisure is defined as a &#x201c;non-obligatory activity that is Intrinsically motivated and engaged in during discretionary time, that is, time not committed to obligatory occupations such as work, self-care, or sleep&#x201d; (
                <xref ref-type="bibr" rid="ref1">American Occupational Therapy Association, 2014</xref>). Depending on personal perceptions, leisure can be defined as either casual, serious, or project based. It can take many different forms, such as instantaneous, brief, and intrinsically fulfilling activities without the need for special skills (i.e., casual leisure); systematic activities carried out by beginners or hobbyists with skills and expertise that could lead to a career itself; or occasionally short-term tasks completed as part of work obligations (
                <xref ref-type="bibr" rid="ref17">Stebbins, 2008</xref>). One aspect of a meaningful life that provides those with mental illness with many benefits is leisure, which includes identity, belonging to themselves, involvement, lowering boredom, and a method of managing their stress (
                <xref ref-type="bibr" rid="ref10">Iwasaki et al., 2014</xref>). Engaging in recreational activities might pose challenges as it involves finding, planning, and carrying out suitable and captivating leisure pursuits (
                <xref ref-type="bibr" rid="ref9">Hein et al., 2020</xref>). Negative symptoms of psychosis may make it difficult for a person to participate in leisure activities (
                <xref ref-type="bibr" rid="ref7">Giacco et al., 2012</xref>).</p>
            <p>According to a study on how people with serious mental illnesses, including schizophrenia, use their time, those with the disease only engage in active leisure activities when they were part of a treatment plan (
                <xref ref-type="bibr" rid="ref24">Yanos &amp; Robilotta, 2011</xref>), indicating that leisure-focused therapies could be crucial to achieving recovery-focused results (
                <xref ref-type="bibr" rid="ref10">Iwasaki et al., 2014</xref>). On this basis, our study aimed to explore the existing literature related to the leisure-based interventions for adults with schizophrenia by identifying the range of study designs.</p>
        </sec>
        <sec id="sec6">
            <title>Methods</title>
            <p>The framework proposed by scoping reviews by 
                <xref ref-type="bibr" rid="ref2">Arksey &amp; O&#x2019;Malley (2005)</xref> was used in the current scoping review.</p>
            <sec id="sec7">
                <title>Research question</title>
                <p>What are the available studies on leisure-based interventions or programs provided for adults with schizophrenia?</p>
            </sec>
            <sec id="sec8">
                <title>Search strategy</title>
                <p>Having specific criteria for searching the relevant articles is a requirement to answer the question framed for any scoping review (
                    <xref ref-type="bibr" rid="ref2">Arksey &amp; O&#x2019;Malley, 2005</xref>). The databases Scopus, PubMed, and Embase were accessed. The grey literature searches through Google scholar were carried out.</p>
                <p>
                    <underline>Search keywords</underline>
                </p>
                <p>&#x201c;Schizophrenia&#x201d; AND &#x201c;Psychosis&#x201d; AND &#x201c;leisure&#x201d; OR &#x201c;leisure activity&#x201d; OR &#x201c;leisure activities&#x201d; OR &#x201c;recreation&#x201d; OR &#x201c;activity&#x201d; OR &#x201c;activity group&#x201d; OR &#x201c;activity groups&#x201d; OR &#x201c;creative activity&#x201d; OR &#x201c;recreational therapy&#x201d; OR &#x201c;leisure-based intervention&#x201d; AND &#x201c;Adults&#x201d; OR &#x201c;Adult&#x201d;. The Boolean search strategy was applied to connect using AND, and OR.</p>
                <p>The following criteria were decided on for the scoping review by all the reviewers:</p>
                <p>
                    <bold>Inclusion criteria</bold>
                </p>
                <p>
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Studies using leisure-based interventions, qualitative studies, single-case studies, cross-sectional and longitudinal studies with or without a comparison control group from January1990 to December 2023 were included.</p>
                        </list-item>
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Full-text articles in only English language were included.</p>
                        </list-item>
                    </list>
                </p>
                <p>
                    <bold>Exclusion criteria</bold>
                </p>
                <p>
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Letter to editors, correspondence articles, viewpoints, ideas, opinions, short communications, and conference proceedings were excluded.</p>
                        </list-item>
                    </list>
                </p>
            </sec>
            <sec id="sec11">
                <title>Study selection</title>
                <p>The search was carried out in the selected databases by two independent reviewers adhering to the established inclusion and exclusion criteria. Following title and abstract screening, the articles included for full-text screening were exported to an Excel sheet for blinding of the selection process. Any disagreement during the selection process was resolved with the help of other reviewers. The included articles were reviewed in full text and data extraction covered the following: title, author(s), year of publication, country, setting, methodology, and results. The extracted data were entered into the Excel sheet, and all the authors reviewed the information. The study details are charted in Table 1(extended data). Three independent authors participated in selecting the studies, and all authors reached a consensus on the studies to be included after discussion. 
                    <xref ref-type="fig" rid="f1">Figure 1</xref> shows the selection of studies in this review.</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>Figure 1. </label>
                    <caption>
                        <title>PRISMA chart.</title>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/166558/6baa7104-f8d7-4249-82bf-806c4b1fd75a_figure1.gif"/>
                </fig>
            </sec>
        </sec>
        <sec id="sec12" sec-type="results">
            <title>Results</title>
            <p>The study yielded 30,194 articles out of which 20,733 articles were screened for title and abstract screening after duplicate removal. After title and abstract screening, 194 articles were eligible for the full text screening, 183 articles were excluded as they did not meet the inclusion criteria, and finally 11 articles were included in the review. In total two studies were pilot interventional study, one randomized controlled study, one case-control, one retrospective study, three were cross sectional, one was cross sectional longitudinal study and two were qualitative in nature. Out of 11 studies, four were conducted in London, England (
                <xref ref-type="bibr" rid="ref5">Dean et al., 2014</xref>; 
                <xref ref-type="bibr" rid="ref13">Ngamaba et al., 2021</xref>; 
                <xref ref-type="bibr" rid="ref18">Shimitras et al., 2003</xref>; 
                <xref ref-type="bibr" rid="ref4">Cella et al., 2016</xref>), two in Philadelphia (
                <xref ref-type="bibr" rid="ref10">Iwasaki et al., 2014</xref>; 
                <xref ref-type="bibr" rid="ref19">Snethen et al. 2012</xref>), two in Australia (
                <xref ref-type="bibr" rid="ref3">Caddy et al., 2011</xref>; 
                <xref ref-type="bibr" rid="ref8">Hayes &amp; Halford, 1996</xref>), one in France (
                <xref ref-type="bibr" rid="ref21">Voruganti et al., 2006</xref>), one in Israel (
                <xref ref-type="bibr" rid="ref11">Lipskaya-Velikovsky et al., 2020</xref>), and one study in the United States of America (
                <xref ref-type="bibr" rid="ref12">McCormick et al., 2012</xref>). In total 993 participants with schizophrenia were studied. All the studies were from high economic countries and participants were recruited from different settings such as hospital inpatients, community, outpatients, and day care centres.</p>
            <sec id="sec13">
                <title>Leisure activities used as an intervention</title>
                <p>Two pilot interventional studies used recreational activities, cooking group as part of the intervention and duration lasted for average of one hour (
                    <xref ref-type="bibr" rid="ref11">Lipskaya-Velikovsky et al., 2020</xref>; 
                    <xref ref-type="bibr" rid="ref19">Snethen et al. 2012</xref>). A Randomized control design study used activity group which included activities like discussions, board games and visits to places of interest (
                    <xref ref-type="bibr" rid="ref5">Dean et al., 2014</xref>), a case control study used camping, kayaking, rock climbing, high and low ropes courses, and a picnic in their summer module and the winter module included skating, snow shoeing, skiing, snowboarding, ice fishing, indoor rock climbing, and bowling (
                    <xref ref-type="bibr" rid="ref21">Voruganti et al., 2006</xref>). A retrospective study investigated on art and craft-based activities like painting, beading, sewing, clay work, paper craft and were used to participants of the group and its outcome in individuals with schizophrenia (
                    <xref ref-type="bibr" rid="ref3">Caddy et al., 2011</xref>).</p>
            </sec>
            <sec id="sec14">
                <title>Leisure activities and association with various factors in individuals with schizophrenia</title>
                <p>
                    <xref ref-type="bibr" rid="ref12">McCormick et al. (2012)</xref> study found that majority of leisure activity perform by people with schizophrenia were sedentary (31%) and sedentary non-leisure (25.7%) and physically active leisure was significantly associated with lower negative emotion. The findings from (
                    <xref ref-type="bibr" rid="ref10">Iwasaki et al., 2014</xref>) emphasize the importance of meanings that persons with mental illness including schizophrenia gain from leisure are connection/belonging, identity, freedom/autonomy and to reduce perceptions of boredom. Also, a greater perception of being actively engaged was a significant predictor of recovery and overall physical and mental health and less frequent psychiatric symptoms. Furthermore, the use of leisure both for coping with stress and reducing boredom significantly predicted fewer psychiatric symptoms. People with psychosis who attend more leisure activities have a higher quality of life. Quality of life score was higher amongst males who attended leisure activities (
                    <xref ref-type="bibr" rid="ref13">Ngamaba et al., 2021</xref>).</p>
            </sec>
            <sec id="sec15">
                <title>Time use and schizophrenia</title>
                <p>Time use studies among schizophrenia found that, people with schizophrenia spent most of their time in passive leisure such as reading, watching TV or videos, relaxing, and sleeping and less time in active lifestyle (
                    <xref ref-type="bibr" rid="ref8">Hayes &amp; Halford, 1996</xref>; 
                    <xref ref-type="bibr" rid="ref18">Shimitras et al., 2003</xref>; 
                    <xref ref-type="bibr" rid="ref4">Cella et al., 2016</xref>).</p>
            </sec>
            <sec id="sec16">
                <title>Facilitators and barriers to participate in leisure activities</title>
                <p>The authors of the reviewed articles have reported of facilitators such as leisure-based intervention being flexible (
                    <xref ref-type="bibr" rid="ref11">Lipskaya-Velikovsky et al., 2020</xref>), client centered, and interest based (
                    <xref ref-type="bibr" rid="ref19">Snethen et al., 2012</xref>), feasible, available, acceptable, and cost-effective (
                    <xref ref-type="bibr" rid="ref21">Voruganti et al., 2006</xref>). Barriers in implementing leisure-based interventions were the characteristic passive lifestyle of patients with schizophrenia, chronic illness, negative symptoms, cognitive deficits, time use and recreational skills deficits that evolve over time (
                    <xref ref-type="bibr" rid="ref8">Hayes &amp; Halford, 1996</xref>; 
                    <xref ref-type="bibr" rid="ref18">Shimitras et al., 2003</xref>; 
                    <xref ref-type="bibr" rid="ref4">Cella et al., 2016</xref>).</p>
            </sec>
            <sec id="sec17">
                <title>Clinical and functional outcomes</title>
                <p>A novel adventure- and recreation-based group intervention was found to be marginally better than standard clinical care in terms of perceived cognitive deficits and functioning, while significant improvements were observed in terms of global functioning and self-esteem, there was a strikingly significant weight loss (mean 12 lb) among study subjects over the course of the year (
                    <xref ref-type="bibr" rid="ref21">Voruganti et al., 2006</xref>). Studies using recreational activities as interventions found improvement in several elements of cognitive function including language understanding, executive functioning, functional capacity and visual memory, increased community involvement, developing coping skills, positive and negative schizophrenia symptoms (
                    <xref ref-type="bibr" rid="ref11">Lipskaya-Velikovsky et al., 2020</xref>; 
                    <xref ref-type="bibr" rid="ref19">Snethen et al., 2012</xref>; 
                    <xref ref-type="bibr" rid="ref5">Dean et al., 2014</xref>). A retrospective study found that use of creative activities in the inpatient setting has potential benefits for people experiencing mental health problem including reductions in self-reported psychological distress and clinician-rated symptoms and improvement in daily functioning (
                    <xref ref-type="bibr" rid="ref3">Caddy et al., 2011</xref>).</p>
            </sec>
        </sec>
        <sec id="sec18" sec-type="discussion">
            <title>Discussion</title>
            <p>This scoping review attempted to investigate the use of leisure as a form of intervention for adults with schizophrenia. Research exploring leisure-based interventions for individuals with schizophrenia underscored their multifaceted benefits (
                <xref ref-type="bibr" rid="ref21">Voruganti et al., 2006</xref>; 
                <xref ref-type="bibr" rid="ref3">Caddy et al., 2011</xref>), showcasing improvements in self-esteem, functioning, and symptom reduction, advocating for their role as complementary therapies in schizophrenia rehabilitation. Engaging in leisure activities significantly associated with lower psychiatric symptoms, coping with stress, reducing boredom, predicting recovery and overall health and increased scores on quality of life among people with schizophrenia (
                <xref ref-type="bibr" rid="ref10">Iwasaki et al., 2014</xref>; 
                <xref ref-type="bibr" rid="ref12">McCormick et al., 2012</xref>).</p>
            <p>
                <xref ref-type="bibr" rid="ref19">Snethen et al. (2012)</xref> patient-centered intervention demonstrated enhanced planning abilities and community involvement through tailored recreational activities. 
                <xref ref-type="bibr" rid="ref10">Iwasaki et al. (2014)</xref> study underscored how leisure-generated meanings and active engagement significantly predict recovery and mental health improvements. Similarly, 
                <xref ref-type="bibr" rid="ref4">Cella et al. (2016)</xref> showed significant differences in time utilization between individuals with schizophrenia and the general population, revealing the disorder's impact on social engagement. 
                <xref ref-type="bibr" rid="ref11">Lipskaya-Velikovsky et al. (2020)</xref> and 
                <xref ref-type="bibr" rid="ref13">Ngamaba et al. (2021)</xref> highlighted the efficacy of occupational connections and increased leisure engagement, respectively, in enhancing recovery and quality of life for schizophrenia patients. These findings collectively advocate for diverse leisure-based interventions personalized to individual preferences as promising additions to standard treatments for improving the lives of those with schizophrenia. Occupational therapists have potential role in using leisure-based activities as part of their treatment to improve functioning among individuals with schizophrenia in various settings.</p>
            <p>The duration of sessions provided ranged from 45 minutes to 1 hour. The ambiguity in the protocol followed could be due to the client centered nature of the leisure-based intervention. Developing a protocol for implementation of leisure-based intervention for persons with schizophrenia could be beneficial in various mental health settings. This would also aid in gauging the effectiveness of the leisure-based intervention in better possible ways such as through studies with higher rigor. The types of leisure activities selected in the studies varied could be due to cultural factors, feasibility, acceptability, and affordability. Nevertheless, the leisure-based interventions are easily adaptable because of which these interventions could be practiced even in the community.</p>
            <sec id="sec19">
                <title>Strength and limitations</title>
                <p>To the best of our knowledge, this is the first review on leisure-based interventions in individuals with schizophrenia. The limitation of our study is that only published literature in English was searched in the current review, which may have resulted in missing relevant studies. The reviewers have tried all possible ways to look for relevant articles, but individual biases of the authors may not be negated. The current review may help future researchers to conduct relevant research related to gaps identified in the current review. Most of the studies identified in the current scoping review have found that there is a positive effect of leisure-based interventions in treatment of schizophrenia, but there is the risk of bias that invites us to be cautious when interpreting these results.</p>
            </sec>
            <sec id="sec20">
                <title>Gaps identified and future implications</title>
                <p>There are limited studies on leisure-based interventions among individuals with schizophrenia. Future studies may focus on evaluating the effectiveness of leisure-based interventions specifically on various occupations such as activities of daily living, instrumental activities of daily living, social participation, sleep and rest, other associated factors such as self-confidence, motivation, emotional expressions, and communication skills. Also, studies could be done in developing guidelines in terms of duration and the type of modalities that could be used for persons with schizophrenia. The studies could be done in low middle income and middle-income countries using different study designs to determine the best means of conducting research on this topic. The study also highlights a need of conducting randomized controlled trials and mixed method studies to understand the effectiveness of leisure-based interventions in schizophrenia.</p>
            </sec>
        </sec>
        <sec id="sec21" sec-type="conclusion">
            <title>Conclusion</title>
            <p>Overall, the purpose of this review was to gather and describe the available research on the use of leisure as an intervention, specifically among individuals with schizophrenia. The study highlights the need to conduct research using leisure-based interventions with various study designs especially randomized control trial to understand its effectiveness among individuals with schizophrenia.</p>
        </sec>
    </body>
    <back>
        <sec id="sec24" sec-type="data-availability">
            <title>Data availability</title>
            <p>No data associated with this article</p>
            <sec id="sec25">
                <title>Extended data</title>
                <p>Figshare: Leisure based Interventions extended files, 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.25810243.v1">https://doi.org/10.6084/m9.figshare.25810243.v1</ext-link> (
                    <xref ref-type="bibr" rid="ref14">Nishad &amp; Nagaraj, 2024</xref>).</p>
                <p>This project contains the following extended data:</p>
                <p>
Table 1 Data charting of the included studies</p>
                <p>
Figure 1 PRISMA Chart</p>
                <p>PRISMA Sc-R Checklist (
                    <xref ref-type="bibr" rid="ref20">Tricco et al., 2018</xref>)</p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
            </sec>
        </sec>
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    <sub-article article-type="reviewer-report" id="report301277">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.166558.r301277</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Giuliani</surname>
                        <given-names>Luigi</given-names>
                    </name>
                    <xref ref-type="aff" rid="r301277a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r301277a1">
                    <label>1</label>University of Campania Luigi Vanvitelli, Naples, Italy</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>6</day>
                <month>8</month>
                <year>2024</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Giuliani L</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
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        </front-stub>
        <body>
            <p>The study by Nishad et al. aims to explore the existing literature related to the leisure-based interventions for adults with schizophrenia by identifying the range of study designs. The results of the present study highlight the need to conduct further research on leisure-based interventions using rigorous study designs like randomized controlled trials and mixed methods to understand its effectiveness among individuals with schizophrenia.</p>
            <p> The study topic is timely and interesting. However, according to the comments provided below, some important issues should be addressed.</p>
            <p> &#x00a0; 
                <list list-type="bullet">
                    <list-item>
                        <p>Abstract</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>The aims of the study are missing.</p>
                    </list-item>
                    <list-item>
                        <p>In the results section, listing the methodology of all the studies included in the review might be removed.</p>
                    </list-item>
                    <list-item>
                        <p>In the results section, are reported only the findings of qualitative studies. Please report also the quantitative results.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Introduction</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>Citations after the sentences &#x201c;Approximately 24 million individuals worldwide, or 1 in 300, are affected by schizophrenia&#x201d; and &#x201c;In adulthood, the corresponding rate is 1 in 222&#x201d; are missing. Please add them.</p>
                    </list-item>
                    <list-item>
                        <p>The sentence &#x201c;One of the main mental health disorders contributing to the global disease burden is schizophrenia, that also affects social functioning&#x201d; does not appear fluid within the paragraph and it could be changed with &#x201c;Schizophrenia is one of the main mental health disorders contributing to the global disease burden, affecting different functioning domains, among which social functioning&#x201d;.</p>
                    </list-item>
                    <list-item>
                        <p>Does &#x201c;systematic activities carried out by beginners or hobbyists with skills and expertise that could lead to a career itself&#x201d; and &#x201c;occasionally short-term tasks completed as part of work obligations&#x201d; correspond respectively to serious- and project-based leisure activities? Please specify.</p>
                    </list-item>
                    <list-item>
                        <p>The sentence &#x201c;One aspect of a meaningful life that provides those with mental illness with many benefits is leisure, which includes identity, belonging to themselves, involvement, lowering boredom, and a method of managing their stress&#x201d; does not appear fluid within the paragraph. Please change it, linking the sentence with the previous one.</p>
                    </list-item>
                    <list-item>
                        <p>The authors states that &#x201c;negative symptoms of psychosis may make it difficult for a person to participate in leisure activities&#x201d;. The concept could be further discussed, more references are needed and also the impact of cognitive deficit on participating in leisure activity should be examined.</p>
                    </list-item>
                    <list-item>
                        <p>The aim of the study should be modified. Instead of prioritizing the identification of the range of study designs, the focus should be placed on the findings of the included studies, highlighting the impact and utilization of leisure-based interventions in adults with schizophrenia.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Methods</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>(Major concern) I have some concerns regarding the search string. By using "schizophrenia AND psychosis," there is a risk, albeit minimal, of excluding studies on patients with schizophrenia that do not include the term psychosis. Additionally, parentheses were not used, which might have resulted in missing some works that could have been included.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Results</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>I recommend reorganizing the presentation of the results because the current format might be unclear. For instance, it is not evident why the sections "Leisure activities and association with various factors in individuals with schizophrenia", "Time use and schizophrenia", and "Clinical and functional outcome" are separated, as they appear to summarize similar results.</p>
                    </list-item>
                    <list-item>
                        <p>When listing the locations where the studies were conducted, the authors sometimes use the city and other times the country. This leads to inconsistencies, such as separating the study conducted in the USA from the one conducted in Philadelphia. In my opinion, it would be better to choose a single classification criterion to ensure consistency.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Discussion:</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>The discussion section needs to be completely rewritten. The authors merely restate the results of individual studies instead of organizing the discussion around the following suggested points:</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Discuss the finding that patients with schizophrenia spend little time engaging in leisure activities and that the activities they do engage in are usually passive.</p>
                    </list-item>
                    <list-item>
                        <p>Discuss the fact that the included studies in the review show that engaging in leisure activities benefits patients with schizophrenia. Specifically, address how these activities impact cognitive, clinical, functional, and quality of life dimensions.</p>
                    </list-item>
                    <list-item>
                        <p>Discuss the studies that utilized leisure-based interventions for patients with schizophrenia. Summarize the findings of these studies, and examine any differences in outcomes based on sample size, study design, and type of intervention as reported in the included studies.</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>The conclusions should include a consideration of how promising and important leisure-based interventions can be, if the authors believe they are. This addition would highlight the potential value and significance of these interventions in the treatment and support of patients with schizophrenia.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>Other</p>
                    </list-item>
                </list> The manuscript would benefit from a review by a native English speaker due to the presence of small but frequent grammatical and spelling errors. Improving the language quality would enhance the clarity and readability of the paper.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Partly</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Not applicable</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Not applicable</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Mental disorders. Schizophrenia and other psychotic disorders. Psychotherapy, psychosocial interventions and and cognitive remediation.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment12359-301277">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Mysore Nagaraj</surname>
                            <given-names>Anil Kumar</given-names>
                        </name>
                        <aff>Psychiatry, Manipal Academy of Higher Education, Manipal, Karnataka, India</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>We declare no competing interests.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>3</day>
                    <month>9</month>
                    <year>2024</year>
                </pub-date>
            </front-stub>
            <body>
                <p>
                    <bold>Abstract</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>The aims of the study are missing.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: </bold>- 
                    <bold>Thank you for identifying this error. We have incorporated it in the manuscript.</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>In the results section, listing the methodology of all the studies included in the review might be removed.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: -</bold> 
                    <bold>Thank you. We have removed it in the revised manuscript</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>In the results section, are reported only the findings of qualitative studies. Please report also the quantitative results.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: -</bold> 
                    <bold>Thank you for the suggestion. We have reported the quantitative studies as well in the revised in the manuscript</bold>
                </p>
                <p> </p>
                <p> 
                    <bold>Introduction</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>Citations after the sentences &#x201c;Approximately 24 million individuals worldwide, or 1 in 300, are affected by schizophrenia&#x201d; and &#x201c;In adulthood, the corresponding rate is 1 in 222&#x201d; are missing. Please add them.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:- We have inserted the citation- (World Health Organization, 2022) after the above sentences in the revised manuscript, in paragraph 1, lines 5 and 6. Thank you.</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>The sentence &#x201c;One of the main mental health disorders contributing to the global disease burden is schizophrenia, that also affects social functioning&#x201d; does not appear fluid within the paragraph and it could be changed with &#x201c;Schizophrenia is one of the main mental health disorders contributing to the global disease burden, affecting different functioning domains, among which social functioning&#x201d;.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: - Thank you for the suggestion. We have changed it as above in the revised manuscript</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>Does &#x201c;systematic activities carried out by beginners or hobbyists with skills and expertise that could lead to a career itself&#x201d; and &#x201c;occasionally short-term tasks completed as part of work obligations&#x201d; correspond respectively to serious- and project-based leisure activities? Please specify.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:-</bold> Yes, the phrases "systematic activities carried out by beginners or hobbyists with skills and expertise that could lead to a career itself" and "occasionally short-term tasks completed as part of work obligations" correspond to serious- and project-based leisure activities, respectively. This has been clarified in the second paragraph of the introduction in the manuscript now. Thanks.</p>
                <p> &#x00a0; 
                    <list list-type="order">
                        <list-item>
                            <p>The sentence &#x201c;One aspect of a meaningful life that provides those with mental illness with many benefits is leisure, which includes identity, belonging to themselves, involvement, lowering boredom, and a method of managing their stress&#x201d; does not appear fluid within the paragraph. Please change it, linking the sentence with the previous one.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:- Thank you for the suggestion. We have revised and reworded the sentences in the 2
                        <sup>nd</sup> paragraph of the introduction in the manuscript.</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="order">
                        <list-item>
                            <p>The authors state that &#x201c;negative symptoms of psychosis may make it difficult for a person to participate in leisure activities&#x201d;. The concept could be further discussed, more references are needed and also the impact of cognitive deficit on participating in leisure activity should be examined.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:- &#x00a0;Thank you for the suggestion. We have revised this in the manuscript, cited more references for the impact of negative symptoms, and added existing studies that mention the impact of cognitive deficit on participating in leisure activity. The entire paragraph three of the introduction has been added to include the above.</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="order">
                        <list-item>
                            <p>The aim of the study should be modified. Instead of prioritizing the identification of the range of study designs, the focus should be placed on the findings of the included studies, highlighting the impact and utilization of leisure-based interventions in adults with schizophrenia.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:- Thank you for identifying this. We have modified the last paragraph of the introduction as suggested above.</bold>
                </p>
                <p> </p>
                <p> 
                    <bold>Method</bold> 
                    <list list-type="order">
                        <list-item>
                            <p>(Major concern) I have some concerns regarding the search string. By using "schizophrenia AND psychosis," there is a risk, albeit minimal, of excluding studies on patients with schizophrenia that do not include the term psychosis. Additionally, parentheses were not used, which might have resulted in missing some works that could have been included.</p>
                        </list-item>
                    </list> 
                    <bold>Reply:-</bold> 
                    <bold>The authors used the &#x2018;OR&#x2019; Boolean operator for schizophrenia OR psychosis. By oversight, while mentioning this in the manuscript it was typed as AND. The parentheses were utilized during the search depending on the databases that we used. Thus, it is unlikely that we have missed any studies. We are sorry for the error in the manuscript (AND instead of OR). We have now changed it to OR in the manuscript.</bold>
                </p>
                <p> </p>
                <p> </p>
                <p> </p>
                <p> </p>
                <p> 
                    <bold>Results: -</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="order">
                        <list-item>
                            <p>I recommend reorganizing the presentation of the results because the current format might be unclear. For instance, it is not evident why the sections "Leisure activities and association with various factors in individuals with schizophrenia", "Time use and schizophrenia", and "Clinical and functional outcome" are separated, as they appear to summarize similar results.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: -</bold>
                </p>
                <p> 
                    <bold>Thank you for this observation. We initially thought that some studies have a specific objective that they can be classified into groups, however, there are overlaps and so we have now merged all the following studies under one group of &#x201c;leisure as a therapeutic intervention&#x201d; &#x2013;</bold>
                </p>
                <p> 
                    <bold>(Lipskaya-Velikovsky et al., 2020; Snethen et al., 2012; Dean et al., 2014; Voruganti et al., 2006; Caddy et al., 2011; McCormick et al., 2012; Iwasaki et al., 2014, Hayes &amp; Halford 1996; Shimitras et al., 2003; Cella et al., 2016; Ngamaba et al. (2021).</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="order">
                        <list-item>
                            <p>When listing the locations where the studies were conducted, the authors sometimes use the city and other times the country. This leads to inconsistencies, such as separating the study conducted in the USA from the one conducted in Philadelphia. In my opinion, it would be better to choose a single classification criterion to ensure consistency.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: - Thank you for the suggestion. We have opted to use the name of the country and have changed it accordingly in the first paragraph of the result.</bold>
                </p>
                <p> </p>
                <p> </p>
                <p> </p>
                <p> </p>
                <p> </p>
                <p> 
                    <bold>Discussion</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="bullet">
                        <list-item>
                            <p>Discuss the finding that patients with schizophrenia spend little time engaging in leisure activities and that the activities they do engage in are usually passive.</p>
                        </list-item>
                    </list> Reply:- &#x00a0;
                    <bold>Thank you for the suggestion. We have changed the entire discussion as suggested.</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="bullet">
                        <list-item>
                            <p>Discuss the fact that the included studies in the review show that engaging in leisure activities benefits patients with schizophrenia. Specifically, address how these activities impact cognitive, clinical, functional, and quality of life dimensions.</p>
                        </list-item>
                    </list> 
                    <bold>Reply: - Thank you for the suggestion. We have revised accordingly in the manuscript</bold>
                </p>
                <p> &#x00a0; 
                    <list list-type="bullet">
                        <list-item>
                            <p>Discuss the studies that utilized leisure-based interventions for patients with schizophrenia. Summarize the findings of these studies, and examine any differences in outcomes based on sample size, study design, and type of intervention as reported in the included studies.</p>
                        </list-item>
                    </list> 
                    <bold>Reply</bold>:- 
                    <bold>Thank you for the suggestion. We have discussed the above points in the modified discussion.</bold>
                </p>
                <p> </p>
                <p> 
                    <bold>The conclusions </bold>
                </p>
                <p> should include a consideration of how promising and important leisure-based interventions can be, if the authors believe they are. This addition would highlight the potential value and significance of these interventions in the treatment and support of patients with schizophrenia.</p>
                <p> 
                    <bold>Reply:- </bold>
                    <bold>Conclusion modified in the manuscript. Thank you.</bold>
                </p>
                <p> </p>
                <p> 
                    <bold>OTHER CHANGES:</bold> 
                    <list list-type="order">
                        <list-item>
                            <p> 
                                <list list-type="order">
                                    <list-item>
                                        <p>
                                            <bold>We have now included 11 additional references (5 in introduction and 6 in discussion). These are cited in the text as well as listed under bibliography, highlighted in green.</bold>
                                        </p>
                                    </list-item>
                                    <list-item>
                                        <p>
                                            <bold>Some rewording done in strengths &amp; limitations, gaps identified and future implications.</bold>
                                        </p>
                                    </list-item>
                                </list> </p>
                        </list-item>
                    </list>
                </p>
            </body>
        </sub-article>
    </sub-article>
</article>
