<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.171903.2</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Determinants of Quality of Life Among Elderly in a Social Care Center: Emphasis on Sleep</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 2; peer review: 1 approved, 1 not approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Yuliati</surname>
                        <given-names>Yuliati</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Wihardja</surname>
                        <given-names>Hany</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8272-371X</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Pambudi</surname>
                        <given-names>Ari</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Department of Nursing Program,, Universitas Esa Unggul, West Jakarta, Jakarta, Indonesia</aff>
                <aff id="a2">
                    <label>2</label>Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Sabah, 88400, Malaysia</aff>
                <aff id="a3">
                    <label>3</label>Department of Nursing Program, Sekolah Tinggi Ilmu Kesehatan Mayapada, Jakarta, Indonesia</aff>
                <aff id="a4">
                    <label>4</label>Department of Computer Program, Universitas Esa Unggul, West Jakarta, Jakarta, 11510, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:yuliati@esaunggul.ac.id">yuliati@esaunggul.ac.id</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>5</day>
                <month>12</month>
                <year>2025</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>1217</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>3</day>
                    <month>12</month>
                    <year>2025</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Yuliati Y et al.</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-1217/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>The aging population worldwide has led to increased attention toward ensuring a good quality of life (QoL) among the elderly, particularly those residing in long-term care facilities. This study aims to identify the determinants of quality of life among elderly residents in a social care center in West Jakarta.</p>
                </sec>
                <sec>
                    <title>Method</title>
                    <p>This quantitative study employed a descriptive cross-sectional design involving 288 elderly residents from a social care center. Data were collected using structured questionnaires measuring sleep behavior, medication adherence, nutritional intake, infection prevention, physical activity, and QoL.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>The results indicated that sleep behavior was significantly associated with QoL (
                        <italic toggle="yes">p</italic> = 0.002), whereas no statistically significant associations were found between QoL and other variables, including medication adherence, nutritional intake, infection prevention, and physical activity.</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>Sleep quality is a significant determinant of QoL among institutionalized elderly individuals. These findings suggest that sleep behavior should be prioritized in care strategies to improve the quality of life of elderly residents in long-term
 care.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Determinants</kwd>
                <kwd>Elderly</kwd>
                <kwd>Nursing Home</kwd>
                <kwd>Quality of Life</kwd>
                <kwd>Sleep Behavior</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
        <notes>
            <sec sec-type="version-changes">
                <label>Revised</label>
                <title>Amendments from Version 1</title>
                <p>This revised version of the article includes only minor but important corrections to improve accuracy and clarity. First, the affiliation of the first author has been updated and correctly added to ensure appropriate institutional acknowledgment and transparency in authorship information. Second, an error in the description of Table II regarding the categorization of Quality of Life (QoL) levels has been corrected. In the earlier version, the narrative interpretation mistakenly stated that poor QoL was more prominent than good QoL. This has now been revised to accurately reflect the data presented in Table II, which shows that good QoL is the more dominant category. No changes were made to the study findings, statistical results, or conclusions. These adjustments have been conducted solely to ensure the article aligns precisely with the validated data and correct authorship details.</p>
            </sec>
        </notes>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>Introduction</title>
            <p>Aging is a natural and inevitable phase in human development, marked by progressive physical, psychological, and social changes that often result in gradual decline. According to the World Health Organization,
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup> individuals aged 60 years and above are classified as elderly. This phase of life presents challenges such as reduced adaptability to stress, decreased biological and cognitive function, and diminished social interaction, all of which may significantly affect an individual&#x2019;s quality of life (QoL).
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> However, aging should not be viewed solely as a period of decline; with adequate health care, social support, and targeted interventions, many older adults are able to maintain independence, resilience, and a sense of well-being. Thus, understanding the multidimensional impact of aging is essential for developing strategies that promote active aging and improve QoL among the elderly population.</p>
            <p>In Indonesia, caring for the elderly has traditionally been considered a familial responsibility, deeply rooted in cultural values of parental respect and intergenerational support. However, changes in family dynamics, rapid urbanization, and increasing work demands have shifted this paradigm, resulting in a growing number of elderlies being placed in nursing homes or social care centers.
                <sup>
                    <xref ref-type="bibr" rid="ref3">3</xref>
                </sup> While these institutions provide essential health and social services, the transition to institutional living often comes at a psychosocial cost. Many elderly residents report feelings of loneliness, abandonment, and diminished self-worth, particularly when the decision to institutionalize is made without their full consent or participation.
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup> Such experiences not only affect emotional well-being but can also significantly lower overall quality of life, underscoring the need for more person-centered and family-inclusive approaches in elderly care.</p>
            <p>Quality of life among institutionalized elderly is influenced by multiple factors, including physical health, mental well-being, and social connectedness. Social support is recognized as a critical determinant of well-being in later life, offering emotional, informational, and practical assistance that helps older adults maintain autonomy and cope with daily challenges.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> A lack of meaningful interaction can lead to isolation, depression, and poor QoL among residents in social care facilities.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>
                </sup> Studies have suggested that social support can buffer the negative impact of institutionalization. When elderly individuals receive consistent support from family, peers, and the broader community, their sense of purpose and emotional resilience improves. Moreover, opportunities for interaction, recreation, and companionship can significantly enhance their perception of life satisfaction and reduce psychological distress.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>
                </sup>
            </p>
            <p>A preliminary exploration at Tresna Werdha Budi Mulia 2 Social Care Center in Jakarta revealed that residents often felt bored, lonely, and disconnected due to the limited variety of daily activities and minimal opportunities for meaningful interaction. These psychosocial challenges illustrate how institutional living can restrict autonomy and reduce the sense of purpose among the elderly, which in turn may negatively influence their overall quality of life. Motivated by these observations, the present study seeks to examine in greater depth the role of social support&#x2014;both from peers within the institution and from family members or staff&#x2014;in shaping the well-being of elderly individuals residing in social care centers. In this context, the research is directed toward understanding whether, and to what extent, the presence, quality, and consistency of social support can enhance different dimensions of quality of life, including physical health, psychological well-being, and social connectedness. By positioning social support as a central variable, the study aims to provide a clearer picture of how interpersonal and institutional relationships contribute to the lived experiences of older adults in care facilities.</p>
        </sec>
        <sec id="sec6" sec-type="methods">
            <title>Methods</title>
            <p>This study employed a cross-sectional design using a non-probability purposive sampling technique to recruit elderly individuals residing in Tresna Werdha Budi Mulia 2 Social Care Center, West Jakarta. Participants were selected based on specific inclusion and exclusion criteria to ensure the appropriateness of the sample for the research objectives. Data collection was conducted in August 2022 at Tresna Werdha Budi Mulia 2 Social Care Center, Cengkareng, West Jakarta. The inclusion criteria were as follows: (a) elderly individuals who had been residing in the care center for more than one month, (b) aged 46 years or older, and (c) not experiencing severe illness, dementia, hearing impairment, psychological disorders, or decreased consciousness. The exclusion criteria included: (a) individuals with communication disorders, and (b) elderly residents who were unwilling to participate as respondents.</p>
            <p>Data collection utilized three main instruments. First, demographic data were collected using a standardized questionnaire from the World Health Organization. Second, social support was measured using a researcher-developed questionnaire (Section B), which was tested for validity and reliability through a pilot study involving 30 elderly residents at Tresna Werdha Budi Mulia 2 Social Care Center in Cengkareng. Third, the WHOQOL-BREF questionnaire (Section C) was used to assess quality of life across four domains: physical, psychological, social, and environmental. Quality of life scores were categorized into three levels: low (&lt;33), moderate (&#x2265;33 and &lt;67), and high (&#x2265;67). Additionally, the Quality-of-Life Index: Generic Version-III was used to support and compare WHOQOL-BREF findings. Data analysis consisted of univariate and bivariate methods. Univariate analysis was conducted to describe demographic variables such as age, gender, education, marital status, and employment. Bivariate analysis using simple linear regression was applied to examine the influence of physical, psychological, social, and environmental factors on the quality of life.</p>
            <p>The Participant Information Sheet (PIS) and informed consent were verbally administered by the research team, as most participants were older adults and some had visual impairments. Following a detailed verbal explanation and confirmation of comprehension, participants who voluntarily agreed to take part provided their written signatures on the consent form. This procedure was reviewed and approved by the institutional ethics committee to ensure inclusivity, accessibility, and full understanding among all participants.</p>
        </sec>
        <sec id="sec7" sec-type="results">
            <title>Results</title>
            <sec id="sec8">
                <title>Demographic data of participants</title>
                <p>This study involved 288 elderly residents of the Tresna Werdha Budi Mulia 2 Social Care Center in Cengkareng, West Jakarta (
                    <xref ref-type="table" rid="T1">
Table I</xref>). The majority (91.3%) were categorized as early elderly; 54.9% were male; and 45.1% were female. Most participants (66.7%) had a senior high school education background; 71.2% were employed prior to institutionalization; and 62.8% were married.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table I. </label>
                    <caption>
                        <title>Characteristics of participants (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Characteristic</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
n (%)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Age (years)</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Early Elderly (46&#x2013;55)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">263 (91.3)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Late Elderly (56&#x2013;65)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25 (8.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Gender</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Male</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">158 (54.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Female</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">130 (45.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Education Level</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;No Formal Education</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (1.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Elementary School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25 (8.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Junior High School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52 (18.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Senior High School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">192 (66.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Higher Education</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">14 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Employment Status</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Not Working</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">83 (28.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Working</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">205 (71.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Marital Status</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Single</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87 (30.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Married</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">181 (62.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Divorced</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">20 (6.9)</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>The quality of life among 288 elderly residents of the Tresna Werdha Budi Mulia 2 Social Care Center indicated that the majority of respondents (96.9%) had a good quality of life, while only 3.1% experienced a less-than-optimal quality of life (
                    <xref ref-type="table" rid="T2">
Table II</xref>).</p>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table II. </label>
                    <caption>
                        <title>Distribution of Quality of Life (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Quality of Life (QoL)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
n (%)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">279 (96.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Poor</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">9 (3.1)</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>
                    <xref ref-type="table" rid="T2">
Table II</xref> presents the association between several health behavior factors and the quality of life among 288 elderly residents. The data showed that the majority of respondents had good QoL across all categories. For medication adherence, 97.4% of non-adherent individuals and 95.9% of adherent individuals were categorized as having good QoL (
                    <italic toggle="yes">p</italic> = 0.491). In the nutritional intake category, 97.3% of those with fair intake and 95.6% of those with good intake had good QoL (
                    <italic toggle="yes">p</italic> = 0.445). Similar patterns were found in infection prevention (
                    <italic toggle="yes">p</italic> = 1.000) and physical exercise (
                    <italic toggle="yes">p</italic>
 = 0.280), with a high proportion of respondents in each category reporting good QoL.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table III. </label>
                    <caption>
                        <title>Association between health behavior factors and Quality of Life among elderly residents (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variable</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Good QoL n (%)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Poor QoL n (%)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Total (n)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">p-</italic>value</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Medication Adherence</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Non-adherent
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (2.6%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">186 (97.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">191</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.491</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Adherent</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (4.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">93 (95.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">97</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Nutritional Intake</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (2.7%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">214 (97.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">220</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.445</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (4.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">65 (95.6%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">68</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Sleep Pattern</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.0%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">197 (99.0%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">199</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.005
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">7 (7.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">82 (92.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">89</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Infection Prevention</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (3.2%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">181 (96.8%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">187</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.000</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (3.0%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98 (97.0%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">101</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Physical Exercise</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (4.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">188 (95.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">196</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.280</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (1.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91 (98.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">92</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>Levels of statistical significance: p-value &#x2264; 0.05.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <p>Overall, the analysis on 
                    <xref ref-type="table" rid="T3">
Table III</xref> shows statistically significant association was observed between sleep patterns and QoL (
                    <italic toggle="yes">p</italic> = 0.005). Among those with good sleep patterns, 7.9% were identified as having good QoL, compared to 1.0% among those with fair sleep patterns. The other health behavior factors included in the analysis did not demonstrate statistically significant correlations with QoL in this sample of institutionalized elderly individuals.</p>
            </sec>
        </sec>
        <sec id="sec9" sec-type="discussion">
            <title>Discussion</title>
            <p>Quality of life is defined as an individual&#x2019;s perception of their position in life, in the context of their goals, expectations, and social and cultural values.
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> It is a broad, multidimensional concept that includes subjective evaluations of both positive and negative aspects of life.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> Among the elderly population, QoL is influenced by several interrelated factors, such as physical health, psychological well-being, social support, and environmental conditions. In addition, the World Health Organization highlights that QoL is not only related to the absence of disease but also encompasses overall well-being, independence, social relationships, and spiritual aspects. It is a dynamic construct that can change over time due to shifts in health status, life roles, or socioeconomic circumstances. As such, measuring QoL provides a comprehensive indicator of an individual&#x2019;s overall health and serves as an essential outcome in evaluating the effectiveness of healthcare interventions and social policies.</p>
            <p>In this study, the majority of elderly residents in the social care center demonstrated relatively good social support, adequate nutritional intake, and active engagement in disease prevention activities. However, despite these positive behaviors, the overall QoL scores were still found to be moderate or even low in many cases. This finding is consistent with previous revealed that 68.4% of older adults in their study had poor QoL.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> The discrepancy between favorable health-related behaviors and low QoL highlights that objective indicators do not necessarily guarantee subjective well-being. Factors such as loneliness, declining physical capacity, loss of independence, or unmet emotional needs may influence how older adults perceive their quality of life.
                <sup>
                    <xref ref-type="bibr" rid="ref8">8</xref>
                </sup> Thus, QoL assessment should be viewed holistically, incorporating both behavioral measures and individual perceptions to capture the true well-being of the elderly.
                <sup>
                    <xref ref-type="bibr" rid="ref9">9</xref>
                </sup>
            </p>
            <p>One striking finding in this study was that sleep behavior showed a significant association with quality of life (
                <italic toggle="yes">p</italic> = 0.002). Poor sleep has long been associated with diminished cognitive function, mood disorders, and lower life satisfaction among older adults. Although 99% of the elderly participants reported &#x201c;fair&#x201d; sleep quality, their overall QoL scores remained in the moderate or low range. This suggests that even slight disturbances in sleep may have a substantial impact on perceived well-being. Tucker et al emphasized through a systematic review and meta-analysis that poor nutritional status and poor sleep were both linked with reduced QoL in institutionalized older adults, reinforcing the role of fundamental daily behaviors in shaping long-term well-being.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> Similarly, Tatineny et al underscored that sleep architecture changed with age and was often accompanied by insomnia, fragmented sleep, and increased sleep latency, all of which contributed to daytime dysfunction.
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup> These disruptions can lead to irritability, fatigue, cognitive decline, and social withdrawal, thus deteriorating QoL. Furthermore, Gothe et al found that sleep quality was deeply intertwined with physical activity and psychosocial well-being.
                <sup>
                    <xref ref-type="bibr" rid="ref12">12</xref>
                </sup> In their study, better sleep was associated with more consistent physical activity, fewer depressive symptoms, and stronger social support factors that, collectively, predicted higher QoL in community-dwelling older adults.</p>
            <p>Contrary to expectations, this study found no significant association between medication adherence and QoL (
                <italic toggle="yes">p</italic> = 0.491), despite the high rate (97.4%) of non-adherence. One possible explanation is the structured nature of medication administration in institutional settings, where the standardized delivery of prescribed drugs reduces the variability typically caused by individual adherence behaviors. This finding also underscores the multifactorial complexity of chronic illness management among older adults, suggesting that pharmacological treatment alone may not be sufficient to enhance overall well-being. Psychosocial aspects, environmental support, and the presence of comorbidities likely play a more prominent role in shaping QoL than adherence in isolation. Therefore, interventions aimed at improving QoL in elderly populations should adopt a holistic approach that integrates medical, psychological, and social dimensions rather than focusing solely on medication compliance. Nutritional intake also did not show a significant relationship with QoL (
                <italic toggle="yes">p</italic> = 0.445), despite 97.3% of participants reporting adequate food intake. While nutrition remains essential for physical health, Tucker et al found that its effects on QoL may have been moderated by the emotional context of mealtimes and individual autonomy in food choices.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> In institutional settings where food provision is standardized, the absence of choice and emotional connection to food may reduce its impact on subjective well-being.</p>
            <p>Sleep quality again emerged as a central determinant of QoL in older adults. A study by Almondes et al comparing pre-pandemic and pandemic sleep patterns among the elderly revealed that disruptions in sleep habits were associated with increased anxiety and social isolation, leading to lower QoL scores.
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> These findings reinforce the notion that psychological and environmental stability play a critical role in maintaining sleep quality and, by extension, life satisfaction in late adulthood. Disease prevention behavior and physical activity were also not significantly correlated with QoL in this study, possibly due to age-related functional limitations and fear of injury. Physical activity among the elderly often declines due to mobility issues or chronic pain, which may prevent it from translating into perceived improvements in life quality unless accompanied by psychosocial support and autonomy.
                <sup>
                    <xref ref-type="bibr" rid="ref14">14</xref>
                </sup>
            </p>
            <p>In addition, a cross-sectional study found that poor sleep quality was significantly associated with reduced QoL in retired elderly individuals, particularly in domains related to emotional role functioning and general health perception.
                <sup>
                    <xref ref-type="bibr" rid="ref15">15</xref>
                </sup> Other findings highlight the critical role of sleep as a determinant of both physical and psychological well-being in later life.
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> Sleep disturbances not only contribute to fatigue and impaired cognitive function but may also exacerbate feelings of anxiety, depression, and social withdrawal, all of which negatively affect QoL. This suggests that interventions targeting sleep quality&#x2014;such as sleep hygiene education, relaxation techniques, or supportive environmental modifications&#x2014;could indirectly enhance broader aspects of life satisfaction and health-related outcomes among the elderly.</p>
            <p>Given the demonstrated relationship between sleep and QoL, improving sleep behavior should be recognized as a central pillar in geriatric care planning. Simple, non-pharmacological interventions such as sleep hygiene education, optimizing light and noise levels in care environments, and establishing individualized bedtime routines have been shown to produce meaningful improvements in sleep outcomes in institutional settings.
                <sup>
                    <xref ref-type="bibr" rid="ref17">17</xref>
                </sup> Beyond their clinical benefits, such interventions are cost-effective and minimally invasive, making them especially suitable for adoption in resource-limited care homes. Incorporating sleep-focused programs into routine geriatric care not only addresses sleep disturbances directly but also has the potential to indirectly enhance emotional well-being, cognitive function, and overall QoL in older adults. Finally, this study underscores the need for a paradigm shift in evaluating and enhancing the quality of life among older adults in social care institutions. Moving beyond traditional health metrics, a more holistic approach should integrate psychological comfort, environmental tranquility, and consistent social connection&#x2014;factors in which sleep quality often acts as a mediator. Future studies may explore how sleep interventions interact with other domains such as emotional support, social participation, and cognitive functioning to enhance QoL in late life.</p>
            <sec id="sec10">
                <title>Ethical considerations</title>
                <p>Ethical principles were upheld throughout the study. Ethical approval was obtained from the Research Ethics Committee of Universitas Esa Unggul (No. 0923-10.010/DPKE-KEP/FINAL-EA/UEU/X/2023). All participants provided informed consent prior to participation. The study design, including the use of validated instruments and structured methodology, ensured the protection of participants&#x2019; rights and the integrity of the research process. Findings contribute to understanding key determinants of quality of life among institutionalized elderly and support evidence-based interventions in social care settings.</p>
            </sec>
        </sec>
        <sec id="sec11" sec-type="conclusion">
            <title>Conclusion</title>
            <p>This study identified sleep behavior as the only statistically significant determinant of quality of life among elderly individuals residing in a social care center. Despite the majority of participants demonstrating adequate medication adherence, nutritional intake, disease prevention behavior, and physical activity, these factors did not show a significant association with their overall QoL. This suggests that subjective factors, particularly those related to rest and psychological well-being, may hold greater weight in determining the perceived quality of life in late adulthood.</p>
            <p>The findings are consistent with international research, including a meta-analysis by Sella et al. (2023), which highlighted sleep quality as a crucial contributor to emotional, psychological, and functional health among older adults. In care institutions, where autonomy and social interaction may already be limited, disrupted or poor-quality sleep can exacerbate feelings of fatigue, anxiety, and dissatisfaction. Therefore, sleep should be considered not only a physiological necessity but also a central component of person-centered care for the elderly.</p>
            <p>It is recommended that social care facilities integrate sleep-promoting interventions into their routine services, such as sleep hygiene education, calming night-time environments, and individualized bedtime schedules. Furthermore, future research should explore how improving sleep interacts with other psychosocial dimensions to holistically elevate quality of life. Policymakers and practitioners must recognize that addressing sleep quality could serve as a cost-effective and impactful strategy in enhancing the well-being of aging populations, particularly those in institutionalized settings.</p>
        </sec>
    </body>
    <back>
        <sec id="sec14" sec-type="data-availability">
            <title>Data availability</title>
            <p>The datasets generated and analyzed during the current study are available in the Zenodo repository, 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.17309312">https://doi.org/10.5281/zenodo.17309312</ext-link>,
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>
                </sup> under the 
                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International</ext-link> (CC-BY 4.0) licence.</p>
        </sec>
        <ack>
            <title>Acknowledgement</title>
            <p>The authors would like to express their sincere gratitude to all participants for their valuable contributions to this study. The authors also acknowledge the institutional support provided by the Research and Community Service Institute of Universitas Esa Unggul, Indonesia, for facilitating the publication of this article.</p>
        </ack>
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    <sub-article article-type="reviewer-report" id="report451079">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.192434.r451079</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Schrire</surname>
                        <given-names>Zoe Menczel</given-names>
                    </name>
                    <xref ref-type="aff" rid="r451079a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-9903-0899</uri>
                </contrib>
                <aff id="r451079a1">
                    <label>1</label>University of Sydney, Sydney, New South Wales, Australia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>1</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Schrire ZM</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport451079" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This manuscript explores factors related to quality of life (QoL) in an adult population and addresses a topic of clear relevance. However, several conceptual and methodological issues need to be addressed to strengthen the clarity, coherence, and interpretability of the findings.</p>
            <p> </p>
            <p> One key issue concerns the alignment between the stated research question and the measures used in the study. The authors indicate that the aim is 'to understand whether, and to what extent, the presence, quality, and consistency of social support enhance different dimensions of quality of life'. Despite this, social support is not clearly defined, measured, or reported in the methods or results. Clarifying how social support was operationalised or revising the research question to better reflect the measured variables, would substantially improve the coherence of the manuscript.</p>
            <p> </p>
            <p> Greater conceptual clarity is also needed. A clear definition of QoL should be provided earlier in the manuscript, rather than appearing primarily in the discussion. In addition, the manuscript at times uses language that implies causality. Given the observational nature of the study, it would be important to consistently frame the findings as associations and to explicitly acknowledge limitations related to directionality.</p>
            <p> </p>
            <p> The study population and inclusion criteria would benefit from further justification. The age threshold of 46 years appears inconsistent with the manuscript&#x2019;s definition of older adults as those aged 60 years and above. Moreover, most participants were under 55 years of age and employed, suggesting relatively high levels of social engagement. Additional explanation is needed to justify the focus on social support in this sample, along with clearer description of the &#x201c;social care centre&#x201d; context and the level of participant independence.</p>
            <p> </p>
            <p> Several methodological details require clarification. Key variables such as sleep quality, infection prevention, and medication adherence are insufficiently described, with limited information on how these constructs were measured or whether validated tools were used. In particular, the assessment of sleep relies on subjective categories without reference to established or objective measures, which should be acknowledged as a limitation.</p>
            <p> </p>
            <p> A major methodological concern relates to the extreme imbalance in outcome and predictor group sizes. For example, QoL is overwhelmingly classified as &#x201c;good&#x201d; (279 participants) compared with &#x201c;poor&#x201d; (9 participants). When one category dominates to this extent, statistical comparisons and regression estimates become unstable and may be unreliable. Such imbalance substantially limits statistical power to detect true associations and increases the risk of misleading or non-generalisable results. Similar issues appear in other variables, where most groups exceed 90% in a single category. These distributions call into question whether the chosen analytical approach is appropriate for the data. Concerns regarding imbalance are further highlighted in Table 3, where some cell counts do not appear to align logically with reported totals, suggesting possible mislabelling or analytical inconsistencies. If variables were analysed categorically, this approach is problematic given the small cell sizes in some groups. The methods section would benefit from explicit clarification of how variables were entered into the regression models (categorical vs continuous) and whether assumptions for these analyses were met.</p>
            <p> </p>
            <p> In the discussion, the findings are occasionally overstated given the uneven group distributions and limited power. A more cautious interpretation, alongside acknowledgment that the study was conducted in Indonesia and may not generalise to other cultural contexts, would strengthen the manuscript. Finally, the inclusion of a dedicated limitations section is recommended, as several important methodological and interpretive constraints warrant explicit discussion.</p>
            <p> </p>
            <p> Overall, the study addresses a meaningful topic, and with clearer alignment between aims and measures, improved methodological transparency, and more careful interpretation of findings, the manuscript could be substantially strengthened.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>No</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>No</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>No</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>older adults and dementia, sleep and circadian rhythms</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment15355-451079">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Yuliati</surname>
                            <given-names>Yuliati</given-names>
                        </name>
                        <aff>Nursing, Universitas Esa Unggul, West Jakarta, Jakarta, Indonesia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>29</day>
                    <month>1</month>
                    <year>2026</year>
                </pub-date>
            </front-stub>
            <body>
                <p>Hi Zoe,&#x00a0;</p>
                <p> </p>
                <p> Thank you for your valuable suggestions. We greatly appreciate your feedback and will revise the manuscript carefully in line with your comments.</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report439087">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.192434.r439087</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>PRIMA</surname>
                        <given-names>ASHAR</given-names>
                    </name>
                    <xref ref-type="aff" rid="r439087a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0289-8083</uri>
                </contrib>
                <aff id="r439087a1">
                    <label>1</label>Department Of Medical-Surgical Nursing, Universitas Bani Saleh, Margahayu, West Java, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>12</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 PRIMA A</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport439087" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The authors have addressed the minor issues identified in the previous review. The correction of the first author&#x2019;s affiliation has improved the accuracy of the authorship information. Additionally, the revision of the narrative description related to Table II, specifically the clarification that good Quality of Life (QoL) is the dominant category is appropriate and now accurately reflects the presented data. These revisions enhance the clarity and consistency of the manuscript. No further concerns regarding findings or interpretations. The manuscript is acceptable in its current form.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>Gerontology, Geriatric Palliative Care</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report430711">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.189568.r430711</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>PRIMA</surname>
                        <given-names>ASHAR</given-names>
                    </name>
                    <xref ref-type="aff" rid="r430711a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0289-8083</uri>
                </contrib>
                <aff id="r430711a1">
                    <label>1</label>Department Of Medical-Surgical Nursing, Universitas Bani Saleh, Margahayu, West Java, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>21</day>
                <month>11</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 PRIMA A</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
                <license>
                    <license-p>The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport430711" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>1. Presentation clarity and data consistency</p>
            <p> The manuscript contains several internal inconsistencies that must be corrected before the results can be indexed as scientifically credible. 
                <list list-type="bullet">
                    <list-item>
                        <p>Table II reports that 
                            <bold>96.9%</bold> of respondents have 
                            <italic>good</italic> QoL, and 3.1% have 
                            <italic>poor</italic> QoL.</p>
                    </list-item>
                    <list-item>
                        <p>However, the narrative text and Table III state that the majority have 
                            <italic>poor</italic> QoL.</p>
                    </list-item>
                </list> These contradictions indicate either a data labeling error, misclassification, or table misplacement. This must be corrected urgently because it affects the interpretation of the entire study.</p>
            <p> 2. Definition of &#x201c;elderly&#x201d; is inconsistent</p>
            <p> The introduction references WHO standards (&#x2265; 60 years), but: 
                <list list-type="bullet">
                    <list-item>
                        <p>The inclusion criteria list &#x2265; 50 years</p>
                    </list-item>
                    <list-item>
                        <p>A category &#x201c;Early Elderly 46&#x2013;55 years&#x201d; appears in the results</p>
                    </list-item>
                </list> This is inconsistent and scientifically problematic. A clear, single definition of the target population is needed, with justification if the study deviates from WHO cut-offs.</p>
            <p> 3. Instruments and operational definitions are insufficiently described</p>
            <p> The authors state that a &#x201c;researcher-developed&#x201d; social support questionnaire was used but do not provide: 
                <list list-type="bullet">
                    <list-item>
                        <p>item structure</p>
                    </list-item>
                    <list-item>
                        <p>scoring system</p>
                    </list-item>
                    <list-item>
                        <p>cut-off definitions</p>
                    </list-item>
                    <list-item>
                        <p>validity statistics</p>
                    </list-item>
                    <list-item>
                        <p>reliability coefficients (e.g., Cronbach&#x2019;s alpha)</p>
                    </list-item>
                </list> Similarly, the operationalization of &#x201c;sleep behavior,&#x201d; &#x201c;medication adherence,&#x201d; &#x201c;nutritional intake,&#x201d; &#x201c;infection prevention,&#x201d; and &#x201c;physical activity&#x201d; is not described. Without this, the study is 
                <italic>not reproducible</italic>.</p>
            <p> Authors must provide the full questionnaire and scoring rules as supplementary material.</p>
            <p> 4. Statistical analysis is insufficient and partly inappropriate</p>
            <p> The manuscript reports p-values, but the type of statistical tests used are not clearly stated. Moreover: 
                <list list-type="bullet">
                    <list-item>
                        <p>If QoL is categorical (good vs poor), 
                            <bold>linear regression is inappropriate</bold>.</p>
                    </list-item>
                    <list-item>
                        <p>No multivariable analysis was performed to control for confounders (age, gender, education, comorbidity, length of stay).</p>
                    </list-item>
                    <list-item>
                        <p>No effect sizes or confidence intervals are reported.</p>
                    </list-item>
                </list> Given the nature of the variables, 
                <bold>multivariable logistic regression</bold> would be appropriate if QoL is dichotomized. If QoL domain scores are continuous, then multiple linear regression can be used &#x2014; but assumptions must be tested and reported.</p>
            <p> At minimum: 
                <list list-type="bullet">
                    <list-item>
                        <p>report odds ratios / &#x03b2; coefficients</p>
                    </list-item>
                    <list-item>
                        <p>95% confidence intervals</p>
                    </list-item>
                    <list-item>
                        <p>specify exact statistical tests used</p>
                    </list-item>
                    <list-item>
                        <p>provide justification for model selection</p>
                    </list-item>
                </list> 5. Conclusions are overstated</p>
            <p> The manuscript frequently uses causal language (&#x201c;determinants&#x201d;). With a cross-sectional design and no multivariable model, causal inference is not justified. The conclusions should be toned down to &#x201c;associated with.&#x201d;</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>Gerontology, Geriatric Palliative Care</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
    </sub-article>
</article>
