<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.171903.4</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Determinants of Quality of Life Among Older Adults in a Social Care Center: Emphasis on Sleep</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 4; peer review: 1 approved, 1 not approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Yuliati</surname>
                        <given-names>Yuliati</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Wihardja</surname>
                        <given-names>Hany</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8272-371X</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Pambudi</surname>
                        <given-names>Ari</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Sabah, 88400, Malaysia</aff>
                <aff id="a2">
                    <label>2</label>Department of Nursing Program,, Universitas Esa Unggul, West Jakarta, Jakarta, Indonesia</aff>
                <aff id="a3">
                    <label>3</label>Department of Nursing Program, Sekolah Tinggi Ilmu Kesehatan Mayapada, Jakarta, Indonesia</aff>
                <aff id="a4">
                    <label>4</label>Department of Computer Program, Universitas Esa Unggul, West Jakarta, Jakarta, 11510, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:yuliati@esaunggul.ac.id">yuliati@esaunggul.ac.id</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>23</day>
                <month>3</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>1217</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>9</day>
                    <month>3</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Yuliati Y et al.</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-1217/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>The global aging population worldwide has led to increased attention toward ensuring a good quality of life (QoL) among older adults, particularly those residing in long-term care facilities. This study aimed to identify the determinants of quality of life among older adults living in a social care center in West Jakarta.</p>
                </sec>
                <sec>
                    <title>Method</title>
                    <p>This quantitative study employed a descriptive cross-sectional design involving 288 participants from a social care center. Data were collected using structured questionnaires measuring sleep behavior, medication adherence, nutritional intake, infection prevention, physical activity, and quality of life.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>The results indicated that sleep behavior was significantly associated with QoL (
                        <italic toggle="yes">p</italic> = 0.005), whereas no statistically significant associations were found between QoL and other variables, including medication adherence, nutritional intake, infection prevention, and physical activity.</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>Sleep behaviour was identified as a significant association of QoL among institutionalized individuals. These findings suggest that a sleep-focused approach should be prioritized in care strategies to improve the quality of life of older adults in long-term care.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Determinants</kwd>
                <kwd>Elderly</kwd>
                <kwd>Nursing Home</kwd>
                <kwd>Quality of Life</kwd>
                <kwd>Sleep Behavior</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
        <notes>
            <sec sec-type="version-changes">
                <label>Revised</label>
                <title>Amendments from Version 3</title>
                <p>In this revised version, several improvements have been made in response to reviewers&#x2019; comments. The Introduction has been revised to remove references to social support to ensure consistency with the variables analyzed in the study. Additional details have been added to the Methods section to clarify how health-related behaviors, including medication adherence, sleep patterns, nutritional intake, disease prevention practices, and physical exercise, were assessed using structured interview questions. Table III has been corrected to ensure consistency with the data presented in Table II and the bivariate analysis results. The Results and Discussion sections have also been revised to ensure accurate interpretation of the findings and consistency with the statistical outputs. Minor language edits have been made throughout the manuscript to improve clarity and readability.</p>
            </sec>
        </notes>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>Introduction</title>
            <p>Aging is a natural and inevitable phase in human development, marked by progressive physical, psychological, and social changes that often result in gradual decline. According to the World Health Organization,
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup> individuals aged 60 years and above are classified as elderly. This phase of life presents challenges such as reduced adaptability to stress, decreased biological and cognitive function, and diminished social interaction, all of which may significantly affect an individual&#x2019;s quality of life (QoL).
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> However, aging should not be viewed solely as a period of decline. With adequate health care, meaningful daily activities, and supportive living environments, many older adults are able to maintain independence, resilience, and a sense of well-being. Thus, understanding the multidimensional impact of aging is essential for developing strategies that promote active aging and improve QoL among the elderly population.</p>
            <p>In Indonesia, caring for the elderly has traditionally been considered a familial responsibility, deeply rooted in cultural values of parental respect and intergenerational support. However, changes in family dynamics, rapid urbanization, and increasing work demands have shifted this paradigm, resulting in a growing number of elderlies being placed in nursing homes or social care centers.
                <sup>
                    <xref ref-type="bibr" rid="ref3">3</xref>
                </sup> While these institutions provide essential health and social services, the transition to institutional living often comes at a psychosocial cost. Many elderly residents report feelings of loneliness, abandonment, and diminished self-worth, particularly when the decision to institutionalize is made without their full consent or participation.
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup> Such experiences not only affect emotional well-being but can also significantly lower overall quality of life, underscoring the need for more person-centered and family-inclusive approaches in elderly care.</p>
            <p>Quality of life among institutionalized elderly is influenced by multiple factors, including physical health, mental well-being, and social connectedness. Living in residential care facilities can shape how older adults experience daily life, particularly in relation to autonomy, participation in activities, and engagement with others within the institution.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> A lack of meaningful interaction can lead to isolation, depression, and poor QoL among residents in social care facilities.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>
                </sup> Studies have suggested that positive social environments and meaningful engagement can buffer the negative impact of institutionalization. When elderly individuals experience regular interaction with family, peers, and the broader community, their sense of purpose and emotional resilience improves. Moreover, opportunities for interaction, recreation, and companionship, together with healthy daily habits, can significantly enhance their perception of life satisfaction and reduce psychological distress.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>
                </sup>
            </p>
            <p>A preliminary exploration at Tresna Werdha Budi Mulia 2 Social Care Center in Jakarta revealed that residents often felt bored, lonely, and disconnected due to the limited variety of daily activities and minimal opportunities for meaningful interaction. These psychosocial challenges illustrate how institutional living can restrict autonomy and reduce the sense of purpose among the elderly, which in turn may negatively influence their overall quality of life. Motivated by these observations, the present study seeks to explore factors related to the well-being of older adult individuals residing in social care centers. In this context, the research is directed toward understanding whether, and to what extent, health-related factors such as treatment adherence, nutritional status, sleep pattern, and physical activity can enhance different dimensions of quality of life, including physical health, psychological well-being, and social connectedness. By examining various health-related factors, the study aims to provide a clearer understanding of determinants that contribute to the lived experiences and overall well-being of older adults residing in social care facilities.</p>
        </sec>
        <sec id="sec6" sec-type="methods">
            <title>Methods</title>
            <p>This study employed a cross-sectional design using a non-probability purposive sampling technique to recruit older adults individuals residing in Tresna Werdha Budi Mulia 2 Social Care Center, West Jakarta. Participants were selected based on specific inclusion and exclusion criteria to ensure the appropriateness of the sample for the research objectives. Data collection was conducted in August 2022 at Tresna Werdha Budi Mulia 2 Social Care Center, Cengkareng, West Jakarta.</p>
            <p>The inclusion criteria were as follows: (a) participants who had been residing in the care center for more than one month, (b) aged 46 years or older, and (c) not experiencing severe illness, dementia, severe hearing impairment, major psychological disorders, or impaired consciousness. The exclusion criteria included: (a) individuals with communication disorders that could hinder participations, and (b) residents who were unwilling to participate.</p>
            <p>The World Health Organization defines older adults as individuals aged 60 years and above, this study included participants aged 46 years and older to capture early ageing stages. For analytical purposes, participants were categorized into middle-to-older age group (46 &#x2013; 55 years) and older age group (56 &#x2013; 65 years). Participants demonstrated mild to moderate levels of dependency but were able to perform basic activities of daily living independently.</p>
            <p>Data collection utilized two main instruments. First, demographic data were collected using a standardized questionnaire from the World Health Organization. Second, quality of life was assesed using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire, which measures four domains: physical, psychological, social, and environmental. Quality of life scores were categorized into three levels: low (&lt;33), moderate (&#x2265;33 and &lt;67), and high (&#x2265;67). Additionally, the Quality-of-Life Index: Generic Version-III was used to support and compare WHOQOL-BREF findings. Health-related behaviours were assessed using structured interview questions administered by the research team. Five domains were evaluated: medication adherence, sleep patterns, nutritional intake, disease prevention practices, and physical exercise. Each domain consisted of four subjective questions related to participant&#x2019;s daily health practices. Responses were recorded based on participant&#x2019;s self-reported experiences and were subsequently categorized into two levels (fair and good) according to predefined criteria for analysis.</p>
            <p>Additional health-related behaviors, including sleep quality, nutritional intake, and disease prevention activities, were assessed descriptively using structured self-reported items to provide contextual information supporting QoL interpretation. These variables were not intended as primary outcome measures but served as complementary indicators of daily functioning.</p>
            <p>Data analysis consisted of univariate and bivariate methods. Univariate analysis was conducted to describe demographic variables such as age, gender, education, marital status, and employment. Bivariate analysis was conducted using Fisher&#x2019;s Exact Test to examine the associations between categorical variables, including health-related factors and overall quality of life, as several contingency table cells had small expected counts.</p>
            <p>The Participant Information Sheet (PIS) and informed consent were verbally administered by the research team, as most participants were older adults and some had visual impairments. Following a detailed verbal explanation and confirmation of comprehension, participants who voluntarily agreed to take part provided their written signatures on the consent form. This procedure was reviewed and approved by the institutional ethics committee to ensure inclusivity, accessibility, and full understanding among all participants.</p>
        </sec>
        <sec id="sec7" sec-type="results">
            <title>Results</title>
            <sec id="sec8">
                <title>Demographic data of participants</title>
                <p>This study involved 288 older adult residents of the Tresna Werdha Budi Mulia 2 Social Care Center in Cengkareng, West Jakarta (
                    <xref ref-type="table" rid="T1">
Table I</xref>). The majority (91.3%) were categorized as middle-to-older age group; 54.9% were male; and 45.1% were female. Most participants (66.7%) had a senior high school education background; 71.2% were employed prior to institutionalization; and 62.8% were married.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table I. </label>
                    <caption>
                        <title>Characteristics of participants (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Characteristic</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
n (%)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Age (years)</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Middle-to-older age group (46&#x2013;55 years)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">263 (91.3)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Older age group (56&#x2013;65 years)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25 (8.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Gender</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Male</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">158 (54.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Female</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">130 (45.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Education Level</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;No Formal Education</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (1.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Elementary School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25 (8.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Junior High School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52 (18.1)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Senior High School</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">192 (66.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Higher Education</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">14 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Employment Status</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Not Working</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">83 (28.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Working</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">205 (71.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Marital Status</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Single</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87 (30.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Married</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">181 (62.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Divorced</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">20 (6.9)</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>The quality of life among 288 residents of the Tresna Werdha Budi Mulia 2 Social Care Center indicated that the majority of respondents (96.9%) had a good quality of life, while only 3.1% experienced a less-than-optimal quality of life (
                    <xref ref-type="table" rid="T2">
Table II</xref>).</p>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table II. </label>
                    <caption>
                        <title>Distribution of Quality of Life (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Quality of Life (QoL)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
n (%)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">279 (96.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Poor</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">9 (3.1)</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>
                    <xref ref-type="table" rid="T2">
Table II</xref> presents the association between several health behavior factors and the quality of life among 288 older adults. The data showed that the majority of respondents had good QoL across all categories. For medication adherence, most respondents with good QoL were found among non-adherent individuals (186; 66.7%), followed by adherent individuals (93; 33.3%) (
                    <italic toggle="yes">p</italic> = 0.491). In the nutritional intake category, most respondents with good QoL had fair nutritional intake (214; 76.7%), while 65 respondents (23.3%) with good nutritional intake were also categorized as having good QoL (
                    <italic toggle="yes">p</italic>
 = 0.445). Similar patterns were found in infection prevention (
                    <italic toggle="yes">p</italic> = 1.000) and physical exercise (
                    <italic toggle="yes">p</italic> = 0.280), with a high proportion of respondents in each category reporting good QoL.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table III. </label>
                    <caption>
                        <title>Association between health behavior factors and Quality of Life among older adult residents (n = 288).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variable</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Good QoL n (%)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Poor QoL n (%)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Total (n)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">p-</italic>value</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Medication Adherence</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Non-adherent</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">186 (66.7%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (55.6%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">191 (66.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.491</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Adherent</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">93 (33.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (44.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">97 (33.7%)</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Nutritional Intake</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">214 (76.7%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (66.7%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">220 (76.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.445</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">65 (23.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (33.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">68 (23.6%)</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Sleep Pattern</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">197 (70.6%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (22.2%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">199 (69.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.005
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">82 (29.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">7 (77.8%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">89 (30.9%)</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Infection Prevention</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">181 (64.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (66.7%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">187 (64.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.000</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98 (35.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (33.3%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">101 (35.1%)</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Physical Exercise</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Fair</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">188 (67.4%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (88.9%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">196 (68.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.280</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Good</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91 (32.6%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (11.1%)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">92 (31.9%)</td>
                                <td colspan="1" rowspan="1"/>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>Levels of statistical significance: p-value &#x2264; 0.05.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <p>Overall, the analysis on 
                    <xref ref-type="table" rid="T3">Table III</xref> shows statistically significant association between sleep patterns and QoL (
                    <italic toggle="yes">p</italic> = 0.005). Among respondents with good sleep patterns, 82 (29.4%) were categorized as having good QoL, compared with 197 (70.6%) among those with fair sleep patterns. The other health behavior factors included in the analysis did not demonstrate statistically significant correlations with QoL in this sample of institutionalized older adult residents.</p>
            </sec>
        </sec>
        <sec id="sec9" sec-type="discussion">
            <title>Discussion</title>
            <p>Quality of life is defined as an individual&#x2019;s perception of their position in life, in the context of their goals, expectations, and social and cultural values.
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup> It is a broad, multidimensional concept that includes subjective evaluations of both positive and negative aspects of life.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> Among the older adults, QoL is influenced by several interrelated factors, such as physical health, psychological well-being, social support, and environmental conditions. In addition, the World Health Organization emphasizes that QoL is not only merely related to the absence of disease but also reflects overall well-being, independence, social relationships, and spiritual aspects. QoL is a dynamic construct that can change over time in response to shifts in health status, life roles, or socioeconomic circumstances. As such, measuring QoL provides a comprehensive indicator of an individual&#x2019;s overall health and serves as an essential outcome in evaluating the effectiveness of healthcare interventions and social policies.</p>
            <p>In this study, the majority of older adult residents in the social care center were married, had an adequate nutritional intake, and were actively engaged in disease prevention activities. The result also showed that most participants were categorized as having good QoL. Nevertheless, variations in perceived well-being may still occur among instutionalized older adults despite favourable health-related behavior. Previous research has reported that 68.4% of older adults in their study had poor QoL.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> This suggests that objective indicators do not necessarily guarantee subjective well-being. Factors such as loneliness, declining physical capacity, loss of independence, or unmet emotional needs may influence how older adults perceive their quality of life.
                <sup>
                    <xref ref-type="bibr" rid="ref8">8</xref>
                </sup> Therefore, QoL assessment should adopt a holistic perspective, intergrating both behavioral measures and individual perceptions to capture the true well-being of the older adults.
                <sup>
                    <xref ref-type="bibr" rid="ref9">9</xref>
                </sup>
            </p>
            <p>One notable finding in this study was that sleep behavior showed a significant association with quality of life (
                <italic toggle="yes">p</italic> = 0.005). Poor sleep has long been associated with diminished cognitive function, mood disorders, and lower life satisfaction among older adults. Although approximately 70% of the participants reported &#x201c;fair&#x201d; sleep quality, differences in sleep patterns were still associated with variations in QoL among participants. This suggests that even minor disturbances in sleep may be associated with meaningful reductions in perceived well-being. Tucker et al emphasized through a systematic review and meta-analysis that poor nutritional status and poor sleep were both linked with reduced QoL in institutionalized older adults, reinforcing the role of fundamental daily behaviors in shaping long-term well-being.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> Similarly, Tatineny et al underscored that sleep architecture changed with age and was often accompanied by insomnia, fragmented sleep, and increased sleep latency, all of which contributed to daytime dysfunction.
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup> These disruptions can lead to irritability, fatigue, cognitive decline, and social withdrawal, thus deteriorating QoL. Furthermore, Gothe et al found that sleep quality was closely linked with physical activity and psychosocial well-being.
                <sup>
                    <xref ref-type="bibr" rid="ref12">12</xref>
                </sup> Their findings suggest that better sleep is associated with more consistent physical activity, fewer depressive symptoms, and stronger social support factors that, collectively, predicted higher QoL in community-dwelling older adults.</p>
            <p>Contrary to expectations, this study found no significant association between medication adherence and QoL ( 
                <italic toggle="yes">p</italic> = 0.491), although a substantial proportion of participants were categorized as non-adherence to medication. One possible explanation is the structured nature of medication administration in institutional settings, where the standardized delivery of prescribed drugs reduces the variability typically caused by individual adherence behaviors. This finding also underscores the multifactorial complexity of chronic illness management among older adults, suggesting that pharmacological treatment alone may not be sufficient to enhance overall well-being. Psychosocial aspects, environmental support, and the burden of comorbidities may play a more prominent role in shaping QoL than adherence in isolation. Therefore, interventions aimed at improving QoL among older adults should adopt a holistic approach that integrates medical, psychological, and social dimensions rather than focusing solely on medication compliance. Nutritional intake also did not show a significant relationship with QoL (
                <italic toggle="yes">p</italic> = 0.445), despite the majority of participants reporting adequate food intake. While nutrition remains essential for physical health, Tucker et al found that its effects on QoL may have been moderated by the emotional context of mealtimes and individual autonomy in food choices.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> In institutional settings where food provision is standardized, limited choice and reduced emotional engagement with meals may attenuate the impact on subjective well-being.</p>
            <p>Sleep quality again emerged as a significant factor associated of QoL among older adults. A study by Almondes et al comparing pre-pandemic and pandemic sleep patterns among older adults reported that disruptions in sleep habits were associated with increased anxiety and reduced social interaction, which were linked to lower QoL scores.
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> These findings reinforce the notion that psychological and environmental stability play a critical role in maintaining sleep quality and, by extension, life satisfaction in later adulthood. In contrast, disease prevention behavior and physical activity were also not significantly associated with QoL in this study, possibly due to age-related functional limitations and fear of injury. Physical activity among the older adults often declines as a result of mobility limitations or chronic pain, which may prevent it from translating into perceived improvements in life quality unless accompanied by a sense of autonomy and psychological well-being.
                <sup>
                    <xref ref-type="bibr" rid="ref14">14</xref>
                </sup>
            </p>
            <p>In addition, a cross-sectional study found that poor sleep quality was significantly associated with reduced QoL in retired older adults, particularly in domains related to emotional role functioning and general health perception.
                <sup>
                    <xref ref-type="bibr" rid="ref15">15</xref>
                </sup> Other findings highlight the critical role of sleep as a determinant of both physical and psychological well-being in later life.
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> Sleep disturbances may contribute to fatigue and impaired cognitive function but may also be associated with heightened anxiety, depressive symptoms, and social withdrawal, all of which negatively affect QoL. These findings suggests that interventions targeting sleep quality, such as sleep hygiene education, relaxation techniques, or supportive environmental modifications may indirectly enhance broader aspects of life satisfaction and health-related outcomes among older adults.</p>
            <p>Given the demonstrated relationship between sleep and QoL, improving sleep behavior may represent an important consideration in geriatric care planning. Simple, non-pharmacological interventions such as sleep hygiene education, optimizing light and noise levels in care environments, and the establishment of individualized bedtime routines have been shown to be associated with improvements in sleep outcomes in institutional settings.
                <sup>
                    <xref ref-type="bibr" rid="ref17">17</xref>
                </sup> Beyond their potential clinical benefits, such approaches are cost-effective and minimally invasive, making them particularly suitable for implementation in resource-limited social care institutions. Incorporating sleep-focused programs into routine geriatric care not only addresses sleep disturbances directly but also has the potential to indirectly enhance emotional well-being, cognitive function, and overall QoL in older adults. This study further highlights the need for a paradigm shift in evaluation and promotion of quality of life in institutionalized older populations. Moving beyond traditional health metrics, a more holistic approach should integrate psychological comfort and environmental tranquillity, in which sleep quality may acts as a important mediator. Future studies may explore how sleep-focused interventions interact with other domains such as emotional well-being, daily functioning, and cognitive functioning to enhance QoL in later life.</p>
            <p>Several limitations of this study should be acknowledged. First, the cross-sectional design precludes causal inference, and the observed associations should be interpreted with caution. Second, although quality of life was measured using a validated instrument, several health-related behaviors, including sleep quality, nutritional intake, and disease prevention activities were assessed using self-reported descriptive measures, which may be subject to reporting bias. Third, the highly imbalanced distribution of QoL categories may have limited statistical power and affected the robustness of the bivariate analyses. Finally, as the study was conducted in a single social care center among institutionalized older adults with mild to moderate dependency, the findings may not be generalizable to community-dwelling older adults or to other sociocultural contexts.</p>
            <sec id="sec10">
                <title>Ethical considerations</title>
                <p>Ethical principles were upheld throughout the study. Ethical approval was obtained from the Research Ethics Committee of Universitas Esa Unggul (No. 0923-10.010/DPKE-KEP/FINAL-EA/UEU/X/2023). All participants provided informed consent prior to participation. The study design, including the use of validated instruments and structured methodology, ensured the protection of participants&#x2019; rights and the integrity of the research process. Findings contribute to understanding key determinants of quality of life among older adults and support evidence-based interventions in social care settings.</p>
            </sec>
        </sec>
        <sec id="sec11" sec-type="conclusion">
            <title>Conclusion</title>
            <p>This study identified sleep behavior as the only statistically significant associated with quality of life among older adults residing in a social care center. Although the majority of participants demonstrated adequate medication adherence, nutritional intake, disease prevention behavior, and physical activity, these factors were not significantly associated with overall QoL. This finding suggests that subjective dimensions particularly those related to rest and psychological well-being, may play a more prominent role in shaping perceived quality of life in late adulthood than objective health behaviors alone.</p>
            <p>The findings are consistent with international evidence, including a meta-analysis by Sella et al. (2023), which highlighted sleep quality as an important factors associated with emotional, psychological, and functional well-being among older adults. In institutional settings, where autonomy and environmental control may be limited, suboptimal sleep quality sleep may further intensity fatigue, emotional distress, and reduced life satisfaction.</p>
            <p>From a practical perspective, the result suggest that integrate sleep-focused strategies, such as sleep hygiene education, optimization of night time environments, and individualized bedtime schedules. Future studies employing longitudinal or interventional design are needed to further examine how improvements in sleep quality interact with psychological and functional domains to enhance QoL. Overall, addressing sleep quality may represent a feasible and cost-effective approach to supporting well-being among aging populations, particularly those living in intuitional care settings.</p>
        </sec>
    </body>
    <back>
        <sec id="sec14" sec-type="data-availability">
            <title>Data availability</title>
            <p>The datasets generated and analyzed during the current study are available in the Zenodo repository, 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.17309312">https://doi.org/10.5281/zenodo.17309312</ext-link>,
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>
                </sup> under the 
                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International</ext-link> (CC-BY 4.0) licence.</p>
        </sec>
        <ack>
            <title>Acknowledgement</title>
            <p>The authors would like to express their sincere gratitude to all participants for their valuable contributions to this study. The authors also acknowledge the institutional support provided by the Research and Community Service Institute of Universitas Esa Unggul, Indonesia, for facilitating the publication of this article.</p>
        </ack>
        <ref-list>
            <title>References</title>
            <ref id="ref1">
                <label>1</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Michel</surname>
                            <given-names>JP</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Leonardi</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Martin</surname>
                            <given-names>M</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Development of a common scale for measuring healthy ageing across the world: Results from the ATHLOS consortium.</article-title>
                    <source>

                        <italic toggle="yes">International Journal of Epidemiology.</italic>
</source>
                    <year>2021 Jun.</year>;<volume>50</volume>. Geneva: Oxford University Press.</mixed-citation>
            </ref>
            <ref id="ref2">
                <label>2</label>
                <mixed-citation publication-type="book">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Rodr&#x00ed;guez-Mart&#x00ed;nez</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>De-la-Fuente-Robles</surname>
                            <given-names>YM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Mart&#x00ed;n-Cano</surname>
                            <given-names>M d C</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <source>

                        <italic toggle="yes">Quality of life and well-being of Older adults in nursing homes: Systematic review.</italic>
</source>
                    <publisher-name>Social Sciences. Multidisciplinary Digital Publishing Institute (MDPI)</publisher-name>;<year>2023</year>; vol.<volume>12</volume>.</mixed-citation>
            </ref>
            <ref id="ref3">
                <label>3</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Bakerjian</surname>
                            <given-names>D</given-names>
                        </name>
</person-group>:
                    <article-title>Quality of care for older adults in nursing homes: It begins with registered nurses but does not end there!.</article-title>
                    <source>

                        <italic toggle="yes">J. Am. Geriatr. Soc.</italic>
</source>
                    <year>2024</year>;<volume>72</volume>:<fpage>2292</fpage>&#x2013;<lpage>2295</lpage>. California: John Wiley and Sons Inc.
                    <pub-id pub-id-type="doi">10.1111/jgs.18973</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref4">
                <label>4</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Baeriswyl</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Oris</surname>
                            <given-names>M</given-names>
                        </name>
</person-group>:
                    <article-title>Social participation and life satisfaction among older adults: diversity of practices and social inequality in Switzerland.</article-title>
                    <source>

                        <italic toggle="yes">Ageing Soc.</italic>
</source>
                    <year>2023 Jun 30</year>;<volume>43</volume>(<issue>6</issue>):<fpage>1259</fpage>&#x2013;<lpage>1283</lpage>.
                    <pub-id pub-id-type="doi">10.1017/S0144686X21001057</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref5">
                <label>5</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Susanti</surname>
                            <given-names>SM</given-names>
                        </name>
</person-group>:
                    <article-title>The correlation of social support with the quality of life of the elderly.</article-title>
                    <source>

                        <italic toggle="yes">International Journal Of Health Science.</italic>
</source>
                    <year>2025 Jul 7</year>;<volume>5</volume>(<issue>2</issue>):<fpage>148</fpage>&#x2013;<lpage>154</lpage>.
                    <pub-id pub-id-type="doi">10.55606/ijhs.v5i2.5506</pub-id>
                    <ext-link ext-link-type="uri" xlink:href="https://journalshub.org/index.php/ijhs/article/view/5506">Reference Source</ext-link>
                </mixed-citation>
            </ref>
            <ref id="ref6">
                <label>6</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Marzo</surname>
                            <given-names>RR</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Khanal</surname>
                            <given-names>P</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Ahmad</surname>
                            <given-names>A</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Quality of life of the elderly during the COVID-19 pandemic in asian countries: A cross-sectional study across six countries.</article-title>
                    <source>

                        <italic toggle="yes">Life.</italic>
</source>
                    <year>2022 Mar 1</year>;<volume>12</volume>(<issue>3</issue>):<fpage>1</fpage>&#x2013;<lpage>11</lpage>.
                    <pub-id pub-id-type="doi">10.3390/life12030365</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref7">
                <label>7</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Cudjoe</surname>
                            <given-names>TKM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Roth</surname>
                            <given-names>DL</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Szanton</surname>
                            <given-names>SL</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>The epidemiology of social isolation: National health and aging trends study.</article-title>
                    <source>

                        <italic toggle="yes">J. Gerontol. B Psychol. Sci. Soc. Sci.</italic>
</source>
                    <year>2020 Jan 1</year>;<volume>75</volume>(<issue>1</issue>):<fpage>107</fpage>&#x2013;<lpage>113</lpage>.
                    <pub-id pub-id-type="pmid">29590462</pub-id>
                    <pub-id pub-id-type="doi">10.1093/geronb/gby037</pub-id>
                    <pub-id pub-id-type="pmcid">PMC7179802</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref8">
                <label>8</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Rodrigues</surname>
                            <given-names>F</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Monteiro</surname>
                            <given-names>AM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Forte</surname>
                            <given-names>P</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Effects of muscle strength, agility, and fear of falling on risk of falling in older adults.</article-title>
                    <source>

                        <italic toggle="yes">Int. J. Environ. Res. Public Health.</italic>
</source>
                    <year>2023 Mar 1</year>;<volume>20</volume>(<issue>6</issue>):<fpage>1</fpage>&#x2013;<lpage>8</lpage>.
                    <pub-id pub-id-type="doi">10.3390/ijerph20064945</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref9">
                <label>9</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Hidayati</surname>
                            <given-names>AR</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Gondodiputro</surname>
                            <given-names>S</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Rahmiati</surname>
                            <given-names>L</given-names>
                        </name>
</person-group>:
                    <article-title>Elderly Profile of Quality of Life Using WHOQOL-BREF Indonesian Version: A Community-Dwelling.</article-title>
                    <source>

                        <italic toggle="yes">Althea Medical Journal.</italic>
</source>
                    <year>2018 Jun</year>;<volume>5</volume>(<issue>2</issue>):<fpage>105</fpage>&#x2013;<lpage>110</lpage>.
                    <pub-id pub-id-type="doi">10.15850/amj.v5n2.1417</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref10">
                <label>10</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Tucker</surname>
                            <given-names>E</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Luscombe-Marsh</surname>
                            <given-names>N</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Ambrosi</surname>
                            <given-names>C</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Nutritional status and quality-of-life of older adults in aged care: A systematic review and meta-analysis.</article-title>
                    <source>

                        <italic toggle="yes">Exp. Gerontol.</italic>
</source>
                    <year>2022 Jun 1</year>;<volume>162</volume>:<fpage>111764</fpage>&#x2013;<lpage>111768</lpage>.
                    <pub-id pub-id-type="doi">10.1016/j.exger.2022.111764</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref11">
                <label>11</label>
                <mixed-citation publication-type="other">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Tatineny</surname>
                            <given-names>P</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Shafi</surname>
                            <given-names>F</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Gohar</surname>
                            <given-names>A</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <source>

                        <italic toggle="yes">Sleep in the Elderly.</italic>
</source>
                    <publisher-loc>Missouri</publisher-loc>:<year>2020 Sep [cited 2025 Sep 16]</year>.
                    <ext-link ext-link-type="uri" xlink:href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7723148/">Reference Source</ext-link>
                </mixed-citation>
            </ref>
            <ref id="ref12">
                <label>12</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Gothe</surname>
                            <given-names>NP</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Ehlers</surname>
                            <given-names>DK</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Salerno</surname>
                            <given-names>EA</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Physical activity, sleep and quality of life in older adults: Influence of physical, mental and social well-being.</article-title>
                    <source>

                        <italic toggle="yes">Behav. Sleep Med.</italic>
</source>
                    <year>2020 Nov 1</year>;<volume>18</volume>(<issue>6</issue>):<fpage>797</fpage>&#x2013;<lpage>808</lpage>.
                    <pub-id pub-id-type="pmid">31713442</pub-id>
                    <pub-id pub-id-type="doi">10.1080/15402002.2019.1690493</pub-id>
                    <pub-id pub-id-type="pmcid">PMC7324024</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref13">
                <label>13</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Almondes</surname>
                            <given-names>KM</given-names>
                            <prefix>de</prefix>
                        </name>

                        <name name-style="western">
                            <surname>Castro</surname>
                            <given-names>E d AS</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Paiva</surname>
                            <given-names>T</given-names>
                        </name>
</person-group>:
                    <article-title>Sleep habits, quality of life and psychosocial aspects in the older age: Before and during COVID-19.</article-title>
                    <source>

                        <italic toggle="yes">Front. Neurosci.</italic>
</source>
                    <year>2022 Mar 24</year>;<volume>16</volume>(<issue>March</issue>):<fpage>1</fpage>&#x2013;<lpage>10</lpage>.
                    <pub-id pub-id-type="doi">10.3389/fnins.2022.694894</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref14">
                <label>14</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Papp</surname>
                            <given-names>ME</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Grahn-Kronhed</surname>
                            <given-names>AC</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Rauch Lundin</surname>
                            <given-names>H</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Changes in physical activity levels and relationship to balance performance, gait speed, and self-rated health in older Swedish women: A longitudinal study.</article-title>
                    <source>

                        <italic toggle="yes">Aging Clin. Exp. Res.</italic>
</source>
                    <year>2022 Apr 1</year>;<volume>34</volume>(<issue>4</issue>):<fpage>775</fpage>&#x2013;<lpage>783</lpage>.
                    <pub-id pub-id-type="pmid">34784017</pub-id>
                    <pub-id pub-id-type="doi">10.1007/s40520-021-02016-5</pub-id>
                    <pub-id pub-id-type="pmcid">PMC9076716</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref15">
                <label>15</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Sella</surname>
                            <given-names>E</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Miola</surname>
                            <given-names>L</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Toffalini</surname>
                            <given-names>E</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>The relationship between sleep quality and quality of life in aging: A systematic review and meta-analysis.</article-title>
                    <source>

                        <italic toggle="yes">Health Psychol. Rev.</italic>
</source>
                    <year>2023 Jan 2</year>;<volume>17</volume>(<issue>1</issue>):<fpage>169</fpage>&#x2013;<lpage>191</lpage>.
                    <pub-id pub-id-type="pmid">34459704</pub-id>
                    <pub-id pub-id-type="doi">10.1080/17437199.2021.1974309</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref16">
                <label>16</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Marwanasari</surname>
                            <given-names>PA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Thanaya</surname>
                            <given-names>SAP</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Antari</surname>
                            <given-names>NKAJ</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>The relationship between sleep quality and dynamic balance in the elderly.</article-title>
                    <source>

                        <italic toggle="yes">Physical Therapy Journal of Indonesia.</italic>
</source>
                    <year>2024 Jan 1</year>;<volume>5</volume>(<issue>1</issue>):<fpage>66</fpage>&#x2013;<lpage>70</lpage>.
                    <pub-id pub-id-type="doi">10.51559/ptji.v5i1.192</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref17">
                <label>17</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Jazayeri</surname>
                            <given-names>E</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Kazemipour</surname>
                            <given-names>S</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Hosseini</surname>
                            <given-names>SR</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Quality of life in the elderly: A community study.</article-title>
                    <source>

                        <italic toggle="yes">Caspian J. Intern. Med.</italic>
</source>
                    <year>2023</year>;<volume>14</volume>(<issue>3</issue>):<fpage>534</fpage>&#x2013;<lpage>542</lpage>.
                    <pub-id pub-id-type="pmid">37520884</pub-id>
                    <pub-id pub-id-type="doi">10.22088/cjim.14.3.543</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref18">
                <label>18</label>
                <mixed-citation publication-type="data">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Wihardja</surname>
                            <given-names>H</given-names>
                        </name>
</person-group>:
                    <data-title>Dataset of &#x201c;Determinants of Quality of Life Among Elderly in a Social Care Center: Emphasis on Sleep Behavior&#x201d;.</data-title>[Data set].
                    <source>

                        <italic toggle="yes">Determinants of Quality of Life Among Elderly in a Social Care Center: Emphasis on Sleep Behavior. Zenodo.</italic>
</source>
                    <year>2025</year>.
                    <pub-id pub-id-type="doi">10.5281/zenodo.17364706</pub-id>
                </mixed-citation>
            </ref>
        </ref-list>
    </back>
    <sub-article article-type="reviewer-report" id="report459636">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.196011.r459636</article-id>
            <title-group>
                <article-title>Reviewer response for version 3</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Schrire</surname>
                        <given-names>Zoe Menczel</given-names>
                    </name>
                    <xref ref-type="aff" rid="r459636a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-9903-0899</uri>
                </contrib>
                <aff id="r459636a1">
                    <label>1</label>University of Sydney, Sydney, New South Wales, Australia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>23</day>
                <month>2</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Schrire ZM</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport459636" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.3"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>
                <bold>1.&#x00a0;</bold>I appreciate the authors&#x2019; efforts to incorporate several of the previous comments, including clarifying the rationale for the age inclusion criteria, reducing causal language, and revising the statistical approach. However, although the chi&#x2011;square test has been substituted, the cell sizes remain too small for this test to be valid. As a result, the subsequent discussion interpreting the null findings remains difficult to support. An alternative statistical test more appropriate for sparse data may be needed.</p>
            <p> </p>
            <p> 
                <bold>2.</bold>&#x00a0;In the response to my earlier review, the authors indicated that all references to social support had been removed. However, social support continues to appear throughout the introduction, including the final sentence, which states: &#x201c;By positioning social support as a central variable.&#x201d; This discrepancy should be addressed for clarity and consistency.</p>
            <p> </p>
            <p> 
                <bold>3.</bold>&#x00a0;There still appears to be a discrepancy between Table 2 and Table 3. In Table 3, a substantially larger number of participants are categorised as having poor QoL, whereas Table 2 reports only nine participants in this category. This inconsistency suggests that headings or classifications may still be misaligned and would benefit from verification.</p>
            <p> </p>
            <p> 
                <bold>4.</bold>&#x00a0;The methods section continues to lack detail on how health&#x2011;related behaviors, such as sleep quality, nutritional intake, and disease&#x2011;prevention activities, were assessed. It would be helpful to specify the structured self&#x2011;report items or instruments used to collect these variables.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>No</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>No</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>No</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>older adults and dementia, sleep and circadian rhythms</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment15590-459636">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Yuliati</surname>
                            <given-names>Yuliati</given-names>
                        </name>
                        <aff>Nursing, Universitas Esa Unggul, West Jakarta, Jakarta, Indonesia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>6</day>
                    <month>3</month>
                    <year>2026</year>
                </pub-date>
            </front-stub>
            <body>
                <p>Hi Zoe,</p>
                <p> </p>
                <p> Greetings from Indonesia, and thank you for your time and thoughtful effort in reviewing our manuscript. We greatly appreciate your constructive comments and suggestions, which have been very helpful in improving the clarity and quality of our paper.</p>
                <p> We have carefully revised the manuscript and addressed each of your comments to the best of our ability. Below we provide a detailed response to your feedback.</p>
                <p> </p>
                <p> 1.&#x00a0;I appreciate the authors&#x2019; efforts to incorporate several of the previous comments, including clarifying the rationale for the age inclusion criteria, reducing causal language, and revising the statistical approach. However, although the chi&#x2011;square test has been substituted, the cell sizes remain too small for this test to be valid. As a result, the subsequent discussion interpreting the null findings remains difficult to support. An alternative statistical test more appropriate for sparse data may be needed.</p>
                <p> 
                    <bold>Response: </bold>
                    <italic>Thank you for this important comment. We agree that when contingency table cell counts are small, the chi-square test may not be appropriate. We would like to clarify that the bivariate analysis in this study was actually conducted using 
                        <bold>Fisher&#x2019;s exact test</bold>, which is more suitable for contingency tables with small expected cell counts. However, due to an oversight during manuscript preparation, the statistical method was incorrectly described in the Methods section. We have now revised the Methods section to clearly state that Fisher&#x2019;s exact test was used to examine the associations between categorical variables. The p-values reported in the Results section were derived from Fisher&#x2019;s exact test. To ensure transparency, the corresponding SPSS output indicating Fisher&#x2019;s exact test results has been attached. The manuscript has been revised accordingly to ensure that the statistical methods are accurately described.</italic>
                </p>
                <p> </p>
                <p> 2.&#x00a0;In the response to my earlier review, the authors indicated that all references to social support had been removed. However, social support continues to appear throughout the introduction, including the final sentence, which states: &#x201c;By positioning social support as a central variable.&#x201d; This discrepancy should be addressed for clarity and consistency.</p>
                <p> 
                    <bold>Response:</bold> 
                    <italic>Thank you for highlighting this inconsistency. We apologize for the oversight in the previous version of the manuscript. In response to this comment, we have carefully revised the entire Introduction and removed the remaining references to social support to ensure clarity and consistency with the focus of the study. The final sentence of the Introduction has also been revised to reflect that the study examines health-related factors associated with quality of life, rather than positioning social support as a central variable. The Introduction section has been updated accordingly.</italic>
                </p>
                <p> </p>
                <p> 3.&#x00a0;There still appears to be a discrepancy between Table 2 and Table 3. In Table 3, a substantially larger number of participants are categorised as having poor QoL, whereas Table 2 reports only nine participants in this category. This inconsistency suggests that headings or classifications may still be misaligned and would benefit from verification.</p>
                <p> 
                    <bold>Response:</bold> 
                    <italic>Thank you for carefully pointing out this discrepancy. We apologize for the error in the previous version of Table III. The inconsistency occurred due to an incorrect entry during the table preparation process. We have now corrected Table III so that the QoL categorization is consistent with the data presented in Table II. The revised table now accurately reflects the distribution of participants, with nine respondents categorized as having poor QoL, consistent with the bivariate analysis results. For transparency, the corrected Table III has been updated in the manuscript and corresponds with the bivariate analysis output provided in response to Comment 1.</italic>
                </p>
                <p> </p>
                <p> 4.&#x00a0;The methods section continues to lack detail on how health&#x2011;related behaviors, such as sleep quality, nutritional intake, and disease&#x2011;prevention activities, were assessed. It would be helpful to specify the structured self&#x2011;report items or instruments used to collect these variables.</p>
                <p> 
                    <bold>Response:</bold> 
                    <italic>Thank you for this helpful comment. We agree that additional clarification regarding the assessment of health-related behaviors is important. The Methods section has now been revised to provide a clearer description of how these variables were measured. Specifically, sleep quality, nutritional intake, disease prevention activities, medication adherence, and physical exercise were assessed using structured self-report items administered to participants. The revised manuscript now includes a detailed explanation of the assessment approach and the categorization of responses.</italic>
                </p>
                <p>
                    <italic> </italic>
                </p>
                <p>
                    <italic> 
                        <ext-link ext-link-type="uri" xlink:href="https://drive.google.com/file/d/1zakBMsTRFEYjJv_zA74DK-AiZgTnlwRs/view?usp=share_link">SPSS Output Proof</ext-link>
                    </italic>
                </p>
                <p> </p>
                <p> Thank you again for your valuable input.</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report451079">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.192434.r451079</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Schrire</surname>
                        <given-names>Zoe Menczel</given-names>
                    </name>
                    <xref ref-type="aff" rid="r451079a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-9903-0899</uri>
                </contrib>
                <aff id="r451079a1">
                    <label>1</label>University of Sydney, Sydney, New South Wales, Australia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>1</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Schrire ZM</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport451079" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This manuscript explores factors related to quality of life (QoL) in an adult population and addresses a topic of clear relevance. However, several conceptual and methodological issues need to be addressed to strengthen the clarity, coherence, and interpretability of the findings.</p>
            <p> </p>
            <p> One key issue concerns the alignment between the stated research question and the measures used in the study. The authors indicate that the aim is 'to understand whether, and to what extent, the presence, quality, and consistency of social support enhance different dimensions of quality of life'. Despite this, social support is not clearly defined, measured, or reported in the methods or results. Clarifying how social support was operationalised or revising the research question to better reflect the measured variables, would substantially improve the coherence of the manuscript.</p>
            <p> </p>
            <p> Greater conceptual clarity is also needed. A clear definition of QoL should be provided earlier in the manuscript, rather than appearing primarily in the discussion. In addition, the manuscript at times uses language that implies causality. Given the observational nature of the study, it would be important to consistently frame the findings as associations and to explicitly acknowledge limitations related to directionality.</p>
            <p> </p>
            <p> The study population and inclusion criteria would benefit from further justification. The age threshold of 46 years appears inconsistent with the manuscript&#x2019;s definition of older adults as those aged 60 years and above. Moreover, most participants were under 55 years of age and employed, suggesting relatively high levels of social engagement. Additional explanation is needed to justify the focus on social support in this sample, along with clearer description of the &#x201c;social care centre&#x201d; context and the level of participant independence.</p>
            <p> </p>
            <p> Several methodological details require clarification. Key variables such as sleep quality, infection prevention, and medication adherence are insufficiently described, with limited information on how these constructs were measured or whether validated tools were used. In particular, the assessment of sleep relies on subjective categories without reference to established or objective measures, which should be acknowledged as a limitation.</p>
            <p> </p>
            <p> A major methodological concern relates to the extreme imbalance in outcome and predictor group sizes. For example, QoL is overwhelmingly classified as &#x201c;good&#x201d; (279 participants) compared with &#x201c;poor&#x201d; (9 participants). When one category dominates to this extent, statistical comparisons and regression estimates become unstable and may be unreliable. Such imbalance substantially limits statistical power to detect true associations and increases the risk of misleading or non-generalisable results. Similar issues appear in other variables, where most groups exceed 90% in a single category. These distributions call into question whether the chosen analytical approach is appropriate for the data. Concerns regarding imbalance are further highlighted in Table 3, where some cell counts do not appear to align logically with reported totals, suggesting possible mislabelling or analytical inconsistencies. If variables were analysed categorically, this approach is problematic given the small cell sizes in some groups. The methods section would benefit from explicit clarification of how variables were entered into the regression models (categorical vs continuous) and whether assumptions for these analyses were met.</p>
            <p> </p>
            <p> In the discussion, the findings are occasionally overstated given the uneven group distributions and limited power. A more cautious interpretation, alongside acknowledgment that the study was conducted in Indonesia and may not generalise to other cultural contexts, would strengthen the manuscript. Finally, the inclusion of a dedicated limitations section is recommended, as several important methodological and interpretive constraints warrant explicit discussion.</p>
            <p> </p>
            <p> Overall, the study addresses a meaningful topic, and with clearer alignment between aims and measures, improved methodological transparency, and more careful interpretation of findings, the manuscript could be substantially strengthened.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>No</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>No</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>No</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>older adults and dementia, sleep and circadian rhythms</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment15355-451079">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Yuliati</surname>
                            <given-names>Yuliati</given-names>
                        </name>
                        <aff>Nursing, Universitas Esa Unggul, West Jakarta, Jakarta, Indonesia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>29</day>
                    <month>1</month>
                    <year>2026</year>
                </pub-date>
            </front-stub>
            <body>
                <p>Hi Zoe,&#x00a0;</p>
                <p> </p>
                <p> Thank you for your valuable suggestions. We greatly appreciate your feedback and will revise the manuscript carefully in line with your comments.</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report439087">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.192434.r439087</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>PRIMA</surname>
                        <given-names>ASHAR</given-names>
                    </name>
                    <xref ref-type="aff" rid="r439087a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0289-8083</uri>
                </contrib>
                <aff id="r439087a1">
                    <label>1</label>Department Of Medical-Surgical Nursing, Universitas Bani Saleh, Margahayu, West Java, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>12</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 PRIMA A</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport439087" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The authors have addressed the minor issues identified in the previous review. The correction of the first author&#x2019;s affiliation has improved the accuracy of the authorship information. Additionally, the revision of the narrative description related to Table II, specifically the clarification that good Quality of Life (QoL) is the dominant category is appropriate and now accurately reflects the presented data. These revisions enhance the clarity and consistency of the manuscript. No further concerns regarding findings or interpretations. The manuscript is acceptable in its current form.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>Gerontology, Geriatric Palliative Care</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report430711">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.189568.r430711</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>PRIMA</surname>
                        <given-names>ASHAR</given-names>
                    </name>
                    <xref ref-type="aff" rid="r430711a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0289-8083</uri>
                </contrib>
                <aff id="r430711a1">
                    <label>1</label>Department Of Medical-Surgical Nursing, Universitas Bani Saleh, Margahayu, West Java, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>21</day>
                <month>11</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 PRIMA A</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
                <license>
                    <license-p>The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport430711" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.171903.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>1. Presentation clarity and data consistency</p>
            <p> The manuscript contains several internal inconsistencies that must be corrected before the results can be indexed as scientifically credible. 
                <list list-type="bullet">
                    <list-item>
                        <p>Table II reports that 
                            <bold>96.9%</bold> of respondents have 
                            <italic>good</italic> QoL, and 3.1% have 
                            <italic>poor</italic> QoL.</p>
                    </list-item>
                    <list-item>
                        <p>However, the narrative text and Table III state that the majority have 
                            <italic>poor</italic> QoL.</p>
                    </list-item>
                </list> These contradictions indicate either a data labeling error, misclassification, or table misplacement. This must be corrected urgently because it affects the interpretation of the entire study.</p>
            <p> 2. Definition of &#x201c;elderly&#x201d; is inconsistent</p>
            <p> The introduction references WHO standards (&#x2265; 60 years), but: 
                <list list-type="bullet">
                    <list-item>
                        <p>The inclusion criteria list &#x2265; 50 years</p>
                    </list-item>
                    <list-item>
                        <p>A category &#x201c;Early Elderly 46&#x2013;55 years&#x201d; appears in the results</p>
                    </list-item>
                </list> This is inconsistent and scientifically problematic. A clear, single definition of the target population is needed, with justification if the study deviates from WHO cut-offs.</p>
            <p> 3. Instruments and operational definitions are insufficiently described</p>
            <p> The authors state that a &#x201c;researcher-developed&#x201d; social support questionnaire was used but do not provide: 
                <list list-type="bullet">
                    <list-item>
                        <p>item structure</p>
                    </list-item>
                    <list-item>
                        <p>scoring system</p>
                    </list-item>
                    <list-item>
                        <p>cut-off definitions</p>
                    </list-item>
                    <list-item>
                        <p>validity statistics</p>
                    </list-item>
                    <list-item>
                        <p>reliability coefficients (e.g., Cronbach&#x2019;s alpha)</p>
                    </list-item>
                </list> Similarly, the operationalization of &#x201c;sleep behavior,&#x201d; &#x201c;medication adherence,&#x201d; &#x201c;nutritional intake,&#x201d; &#x201c;infection prevention,&#x201d; and &#x201c;physical activity&#x201d; is not described. Without this, the study is 
                <italic>not reproducible</italic>.</p>
            <p> Authors must provide the full questionnaire and scoring rules as supplementary material.</p>
            <p> 4. Statistical analysis is insufficient and partly inappropriate</p>
            <p> The manuscript reports p-values, but the type of statistical tests used are not clearly stated. Moreover: 
                <list list-type="bullet">
                    <list-item>
                        <p>If QoL is categorical (good vs poor), 
                            <bold>linear regression is inappropriate</bold>.</p>
                    </list-item>
                    <list-item>
                        <p>No multivariable analysis was performed to control for confounders (age, gender, education, comorbidity, length of stay).</p>
                    </list-item>
                    <list-item>
                        <p>No effect sizes or confidence intervals are reported.</p>
                    </list-item>
                </list> Given the nature of the variables, 
                <bold>multivariable logistic regression</bold> would be appropriate if QoL is dichotomized. If QoL domain scores are continuous, then multiple linear regression can be used &#x2014; but assumptions must be tested and reported.</p>
            <p> At minimum: 
                <list list-type="bullet">
                    <list-item>
                        <p>report odds ratios / &#x03b2; coefficients</p>
                    </list-item>
                    <list-item>
                        <p>95% confidence intervals</p>
                    </list-item>
                    <list-item>
                        <p>specify exact statistical tests used</p>
                    </list-item>
                    <list-item>
                        <p>provide justification for model selection</p>
                    </list-item>
                </list> 5. Conclusions are overstated</p>
            <p> The manuscript frequently uses causal language (&#x201c;determinants&#x201d;). With a cross-sectional design and no multivariable model, causal inference is not justified. The conclusions should be toned down to &#x201c;associated with.&#x201d;</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>No</p>
            <p>Reviewer Expertise:</p>
            <p>Gerontology, Geriatric Palliative Care</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
    </sub-article>
</article>
