<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="case-report" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.160982.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Case Report</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Case Report: Isolated osteochondral fracture of the weight-bearing lateral femoral condyle</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 1 approved with reservations]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Almohimeed</surname>
                        <given-names>Abdullah</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Ferjani</surname>
                        <given-names>Mohamed Achraf</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0009-0004-0541-7814</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Abdullah</surname>
                        <given-names>Osama</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Bekkay</surname>
                        <given-names>Mohamed Ali</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Kamoun</surname>
                        <given-names>Khaled</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-0180-5719</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>HafrAl-Baten Health Cluster, Hafar Al Batin, Saudi Arabia</aff>
                <aff id="a2">
                    <label>2</label>University of Tunis El Manar Faculty of Medicine of Tunis, Tunis, Tunis, Tunisia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:Achraffjn@gmail.com">Achraffjn@gmail.com</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>4</day>
                <month>2</month>
                <year>2025</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>156</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>27</day>
                    <month>1</month>
                    <year>2025</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Almohimeed A et al.</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-156/pdf"/>
            <abstract>
                <sec>
                    <title>Introduction</title>
                    <p>Osteochondral fractures (OCF)s of the femoral condyle are rare in pediatric patients but can have significant implications if missed or left untreated. Surgical fixation is often recommended, particularly in young, to restore joint congruency and function.</p>
                </sec>
                <sec>
                    <title>Case report</title>
                    <p>We report the case of a 14-year-old boy who presented with isolated weight-bearing OCF of the lateral femoral condyle following a sports injury. Magnetic resonance imaging (MRI) revealed a 30.4 mm osteochondral fragment confirmed by arthroscopy but unsuitable for percutaneous management due to its size and location. Open reduction and internal fixation were performed using headless compression screws, a technique reserved for those cases where based on sufficient detached fragment bone to facilitate secure fixation and bone-to-bone healing.</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>This case underscores the importance of prompt diagnosis and individualized treatment to prevent long-term joint damage, contributing valuable insights into the management of pediatric femoral osteochondral fractures.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Osteochondral fracture</kwd>
                <kwd>Femoral condyle</kwd>
                <kwd>Pediatric fracture</kwd>
                <kwd>Arthrotomy</kwd>
                <kwd>Case report</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec3" sec-type="intro">
            <title>Introduction</title>
            <p>While osteochondral fractures OCFs have long been recognized, their precise incidence in the pediatric population is not well-established. OCFs around the knee. Typically results from either acute trauma or repetitive microtrauma, such as torsional injuries or patellar dislocations. Radiographic diagnosis can be difficult due to the potentially thin bony component of the osteochondral fragment.
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup> Despite numerous publications describing various surgical techniques for OCFs, a consensus on the optimal approach remains elusive. Historically, surgical management often involved fragment removal unless sufficient subchondral bone was present for anchoring.
                <sup>
                    <xref ref-type="bibr" rid="ref2">2</xref>
                </sup>
            </p>
            <p>Here, we report good radiological and excellent functional outcomes at 18 months postoperatively following fragment fixation of a lateral femoral condyle OCF in a pediatric patient.</p>
        </sec>
        <sec id="sec4">
            <title>Case report</title>
            <sec id="sec5">
                <title>Patient and observation</title>
                <p>

                    <bold>Patient information:</bold> A 14-year-old boy with no significant medical history presented to the emergency department with left knee pain and swelling following a sport injury.</p>
                <p>

                    <bold>Clinical findings:</bold> Initial examination of the left knee revealed swelling, pain, and a positive patellar tap, with no skin lesions observed. Three days post-injury, the patient continued to experience the same symptoms, with increased severity of knee pain.</p>
                <p>

                    <bold>Timeline of current episode:</bold> In May 2023, following a sports-related injury with an unknown mechanism, a child presented with a closed left knee trauma characterized by functional impairment, pain, and swelling, but no skin lesions. Initial radiographs were unremarkable, and the patient was treated symptomatically. Three days later, the child returned with persistent symptoms and increased pain. MRI revealed an osteochondral fracture. Surgical intervention occurred seven days post-injury, initially planned arthroscopically. However, due to the lesion&#x2019;s inaccessibility, an open approach with ORIF using two headless compression screws was performed via a lateral parapatellar incision. Post-operatively, the patient followed a three-month rehabilitation program, including 45 days of non-weight-bearing. At 18 months follow-up, the patient demonstrated excellent results with full range of motion and good quadriceps strength.</p>
                <p>

                    <bold>Diagnostic assessment:</bold> Initial physical examination revealed a painful knee with functional impairment but no deformity or skin lesions. Initial radiographs did not demonstrate any osseous abnormalities (
                    <xref ref-type="fig" rid="f1">
Figure 1</xref>).</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>
Figure 1. </label>
                    <caption>
                        <title>(A) and (B) Radiograph of the left knee showing no detectable abnormalities.</title>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/176952/b38c9dea-c1e5-4297-b563-afa71cd7704f_figure1.gif"/>
                </fig>
                <p>Due to persistent symptoms, MRI was performed, which revealed a 30.4mm osteochondral fracture (
                    <xref ref-type="fig" rid="f2">
Figure 2</xref>).</p>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>
Figure 2. </label>
                    <caption>
                        <title>(A) Frontal and (B) sagittal MRI images of the osteochondral fracture of the lateral condyle.</title>
                    </caption>
                    <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/176952/b38c9dea-c1e5-4297-b563-afa71cd7704f_figure2.gif"/>
                </fig>
                <p>A key diagnostic challenge in such cases is considering the possibility of an osteochondral lesion, especially when initial radiographs are negative, as these fractures can be subtle or even invisible on plain films if the bony component is small.
                    <sup>
                        <xref ref-type="bibr" rid="ref1">1</xref>
                    </sup>
                </p>
                <p>

                    <bold>Diagnosis:</bold> The final diagnosis was an osteochondral fracture of the lateral femoral condyle. Other diagnoses considered, prior to MRI confirmation, included meniscal tear and ligament sprain.</p>
                <p>

                    <bold>Therapeutic interventions:</bold> The patient underwent arthroscopy to visualize the osteochondral fragment and assess for associated ligamentous or meniscal injuries. Arthroscopy confirmed the osteochondral defect and the absence of associated injuries (
                    <xref ref-type="fig" rid="f3">
Figure 3</xref>).</p>
                <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                    <label>
Figure 3. </label>
                    <caption>
                        <title>(A) and (B) loose osteochondral fragment overlying the 
                            <ext-link ext-link-type="uri" xlink:href="https://www.sciencedirect.com/topics/medicine-and-dentistry/lateral-tibial-plateau">lateral tibial plateau</ext-link>, (C) without associated lesions.</title>
                    </caption>
                    <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/176952/b38c9dea-c1e5-4297-b563-afa71cd7704f_figure3.gif"/>
                </fig>
                <p>However, due to the size and location of the fragment, arthroscopic fixation was deemed infeasible. The procedure was converted to an open approach via a lateral parapatellar incision. Open reduction and internal fixation (ORIF) was then performed using two headless compression screws (
                    <xref ref-type="fig" rid="f4">
Figure 4</xref>).</p>
                <fig fig-type="figure" id="f4" orientation="portrait" position="float">
                    <label>
Figure 4. </label>
                    <caption>
                        <title>(A) The debrided defect, (B) temporary fixation of the fragment, (C) fixation with headless screw.</title>
                    </caption>
                    <graphic id="gr4" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/176952/b38c9dea-c1e5-4297-b563-afa71cd7704f_figure4.gif"/>
                </fig>
                <p>Postoperatively, the patient began immediate mobilization with a non-weight-bearing protocol for 45 days, followed by continued physiotherapy for a total of three months.</p>
                <p>

                    <bold>Follow-up and outcome of interventions:</bold> At 18 months post-operatively, the patient demonstrated excellent clinical results with a pain-free, stable, and non-effused knee. Full range of motion was achieved. Radiographs also confirmed excellent results with no evidence of arthritic changes (
                    <xref ref-type="fig" rid="f5">
Figure 5</xref>).</p>
                <fig fig-type="figure" id="f5" orientation="portrait" position="float">
                    <label>
Figure 5. </label>
                    <caption>
                        <title>(A) and (B) The fracture is healing with no evidence of arthritic changes.</title>
                    </caption>
                    <graphic id="gr5" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/176952/b38c9dea-c1e5-4297-b563-afa71cd7704f_figure5.gif"/>
                </fig>
                <p>The patient returned to sports.</p>
                <p>

                    <bold>Patient perspective:</bold> &#x201c;After my knee injury, I was worried I wouldn&#x2019;t be able to play sports again. The initial pain and swelling were really bad. I was glad when the surgery was over, but the recovery was tough. But it was worth it. My knee feels great now, and I&#x2019;m back playing with my friends. I&#x2019;m so grateful to the doctors and physiotherapists who helped me get better.&#x201d;</p>
            </sec>
        </sec>
        <sec id="sec6" sec-type="discussion">
            <title>Discussion</title>
            <p>Traumatic OCFs of the distal femur are relatively uncommon compared to other femoral injuries. The concept of traumatic OCF was first detailed by Milgram in 1943.
                <sup>
                    <xref ref-type="bibr" rid="ref3">3</xref>
                </sup> It is important to differentiate a recent fracture from osteochondritis dissecans (OCD) based on the presence of a trauma-related incident. Recent fractures typically result in fragments that are well-suited for fixation techniques.
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup> OCFs commonly occur on the articular surfaces of bones frequently involved in trauma, such as the glenoid, femur, patella, and talus. The mechanism of injury can vary based on lesion location. Common causes include shearing, rotational or impaction forces, and excessive tangential loading of the articular surface.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup>
            </p>
            <p>The precise incidence of OCFs around the knee remains uncertain. Current evidence suggests a higher frequency in pediatric patients compared to adults.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref8">8</xref>
                </sup> Generalized joint laxity and patellar dislocation are often associated with OCFs.
                <sup>
                    <xref ref-type="bibr" rid="ref8">8</xref>,
                    <xref ref-type="bibr" rid="ref9">9</xref>
                </sup> In patellar dislocations, the contracted quadriceps can exert high pressure on the lateral femoral condyle during patellar reduction, frequently resulting in OCFs.
                <sup>
                    <xref ref-type="bibr" rid="ref5">5</xref>
                </sup> Studies have shown that the osteochondral unit in adolescents has lower resistance to shear forces,
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> while adults exhibit greater fracture resistance at the osteochondral junction.
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup>
            </p>
            <p>Diagnosing OCFs in pediatric patients around the knee can be particularly challenging. Small bony fragments may be overlooked, and the actual size of the cartilage component might be underestimated or misinterpreted as an accessory bone. MRI is the preferred imaging modality for evaluating osteochondral injuries,
                <sup>
                    <xref ref-type="bibr" rid="ref12">12</xref>,
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> while radiographs or computed tomography (CT) scans are more useful for evaluating the bony component of the fragment.</p>
            <p>The management of chondral injuries with tissue loss remains a significant challenge. Recent studies suggest that innovative techniques offer promising results for cartilage repair and improved clinical outcomes. However, a universally accepted treatment approach has yet to be established.
                <sup>
                    <xref ref-type="bibr" rid="ref14">14</xref>,
                    <xref ref-type="bibr" rid="ref15">15</xref>
                </sup>
            </p>
            <p>Key factors influencing the management of pediatric knee osteochondral lesions include lesion location, size, stability, and symptom severity.
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> While fragment fixation is generally considered the gold standard treatment for OCFs, the impact of patient age, fragment size, and the interval between injury and diagnosis on surgical success remains unclear.
                <sup>
                    <xref ref-type="bibr" rid="ref17">17</xref>
                </sup> Current literature supports operative intervention for osteochondral injuries, particularly those involving weight-bearing surfaces, lesions larger than 2 cm
                <sup>2</sup>, and those causing mechanical symptoms.
                <sup>
                    <xref ref-type="bibr" rid="ref18">18</xref>
                </sup> Surgical fixation of acute OCFs in pediatric patients has demonstrated favorable clinical and radiological outcomes,
                <sup>
                    <xref ref-type="bibr" rid="ref8">8</xref>,
                    <xref ref-type="bibr" rid="ref16">16</xref>,
                    <xref ref-type="bibr" rid="ref19">19</xref>
                </sup> likely due to the superior regenerative capacity of pediatric cartilage, facilitated by bony union and chondral extensions from the fragment.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>,
                    <xref ref-type="bibr" rid="ref11">11</xref>
                </sup> Historically, fragment excision was often performed in late-diagnosed cases, treating the fragment as a loose body.
                <sup>
                    <xref ref-type="bibr" rid="ref6">6</xref>,
                    <xref ref-type="bibr" rid="ref20">20</xref>
                </sup> However, this approach can lead to early degenerative changes in the knee due to the resulting defect.
                <sup>
                    <xref ref-type="bibr" rid="ref21">21</xref>,
                    <xref ref-type="bibr" rid="ref22">22</xref>
                </sup> Similarly, untreated intra-articular fragments can cause further cartilage damage and arthritis. Therefore, even in neglected or late-diagnosed cases, fixation remains the preferred treatment strategy.</p>
            <p>Bioabsorbable pins offer the advantage of postoperative MRI compatibility. While multiple pins can enhance rotational stability, they may limit compression of the lesion. Screws, conversely, provide immediate compression and, when used in multiples, rotational stability.
                <sup>
                    <xref ref-type="bibr" rid="ref23">23</xref>
                </sup> Postoperatively, patients can begin rehabilitation and undergo follow-up imaging with CT or MRI.</p>
            <p>The literature provides limited guidance on the minimum bony component size required for OCF fixation. Fabricant et al.
                <sup>
                    <xref ref-type="bibr" rid="ref24">24</xref>
                </sup> reported a 90% success rate in young athletes with chondral-only shear fractures treated with bioabsorbable implants or sutures. Other studies suggest fibrin sealant or tissue glue can be effective for larger fragments lacking sufficient bone for implant fixation.
                <sup>
                    <xref ref-type="bibr" rid="ref25">25</xref>,
                    <xref ref-type="bibr" rid="ref26">26</xref>
                </sup> Schlechter et al.
                <sup>
                    <xref ref-type="bibr" rid="ref16">16</xref>
                </sup> demonstrated good outcomes with bioabsorbable fixation in OCFs with a mean lesion size of 299 mm
                <sup>2</sup>. Hsu et al.
                <sup>
                    <xref ref-type="bibr" rid="ref27">27</xref>
                </sup> recommended headless cannulated screws for fragments larger than 3 cm
                <sup>2</sup> in a pediatric case. These findings suggest that while overall osteochondral fragment size helps determine whether surgical or conservative treatment is warranted, the size of the bony component dictates the specific fixation method (headless screws, adhesives, rods, or sutures).</p>
            <p>Untreated osteochondral defects in children can enlarge with skeletal growth. Furthermore, fibrotic tissue formation on the bony component can reduce fragment size after debridement, potentially leading to incongruity between the fragment and the defect, hindering anatomical reduction. In this case, complete anatomical reduction was achieved, resulting in excellent outcomes at 18 months postoperatively. While the literature suggests eventual removal of metallic implants,
                <sup>
                    <xref ref-type="bibr" rid="ref28">28</xref>
                </sup> we are conducting annual follow-up to monitor for potential articular cartilage damage and to guide the decision regarding implant removal.</p>
            <p>This case contributes to the limited literature on isolated, weight-bearing lateral femoral condyle OCFs in pediatric patients, demonstrating the potential for successful outcomes with careful surgical management and emphasizing the need for individualized treatment approaches.</p>
        </sec>
        <sec id="sec7" sec-type="conclusion">
            <title>Conclusion</title>
            <p>This case highlights the diagnostic challenges associated with isolated OCFs of the weight-bearing portion of the lateral femoral condyle. The subtle radiographic findings in such fractures underscore the importance of advanced imaging, such as MRI, when clinical suspicion remains high despite normal initial radiographs. Furthermore, this case demonstrates the efficacy ORIF when arthroscopic management is not feasible due to fragment size or location. Prompt and appropriate surgical intervention can effectively restore joint congruity and facilitate optimal healing in these challenging pediatric knee injuries.</p>
            <sec id="sec8">
                <title>Ethics</title>
                <p>Ethical approval was not required for the Case report.</p>
            </sec>
        </sec>
        <sec id="sec9">
            <title>Consent to publish</title>
            <p>Written informed consent for publication of their clinical details and/or clinical images was obtained from the patient&#x2019;s parents.</p>
        </sec>
    </body>
    <back>
        <sec id="sec12" sec-type="data-availability">
            <title>Data availability</title>
            <sec id="sec13">
                <title>Underlying data</title>
                <p>No data are associated with this article.</p>
            </sec>
        </sec>
        <ref-list>
            <title>References</title>
            <ref id="ref1">
                <label>1</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Jehan</surname>
                            <given-names>S</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Loeffler</surname>
                            <given-names>MD</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Pervez</surname>
                            <given-names>H</given-names>
                        </name>
</person-group>:
                    <article-title>Osteochondral fracture of the lateral femoral condyle involving the entire weight bearing articular surface fixed with biodegradable screws.</article-title>
                    <source>

                        <italic toggle="yes">J. Pak. Med. Assoc.</italic>
</source>
                    <year>2010</year>;<volume>60</volume>:<fpage>400</fpage>&#x2013;<lpage>401</lpage>.
                    <pub-id pub-id-type="pmid">20527619</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref2">
                <label>2</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Giffin</surname>
                            <given-names>JR</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Annunziata</surname>
                            <given-names>CC</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Vogrin</surname>
                            <given-names>TM</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Primary repair of osteochondral and chondral injury.</article-title>
                    <source>

                        <italic toggle="yes">Oper. Tech. Orthop.</italic>
</source>
                    <year>2001</year>;<volume>11</volume>(<issue>2</issue>):<fpage>83</fpage>&#x2013;<lpage>89</lpage>.
                    <pub-id pub-id-type="doi">10.1016/S1048-6666(01)80016-1</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref3">
                <label>3</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Milgram</surname>
                            <given-names>JE</given-names>
                        </name>
</person-group>:
                    <article-title>Tangential osteochondral fracture of the patella.</article-title>
                    <source>

                        <italic toggle="yes">J. Bone Joint Surg.</italic>
</source>
                    <year>1943</year>;<volume>25</volume>:<fpage>271</fpage>&#x2013;<lpage>280</lpage>.</mixed-citation>
            </ref>
            <ref id="ref4">
                <label>4</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Gracitelli</surname>
                            <given-names>GC</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Tirico</surname>
                            <given-names>LE</given-names>
                        </name>

                        <name name-style="western">
                            <surname>McCauley</surname>
                            <given-names>JC</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Fresh osteochondral allograft transplantation for fractures of the knee.</article-title>
                    <source>

                        <italic toggle="yes">Cartilage.</italic>
</source>
                    <year>2017</year>;<volume>8</volume>(<issue>2</issue>):<fpage>155</fpage>&#x2013;<lpage>161</lpage>.
                    <pub-id pub-id-type="pmid">28345414</pub-id>
                    <pub-id pub-id-type="doi">10.1177/1947603516657640</pub-id>
                    <pub-id pub-id-type="pmcid">PMC5358831</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref5">
                <label>5</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Milgram</surname>
                            <given-names>JW</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Rogers</surname>
                            <given-names>LF</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Miller</surname>
                            <given-names>JW</given-names>
                        </name>
</person-group>:
                    <article-title>Osteochondral fractures: Mechanisms of injury and fate of fragments.</article-title>
                    <source>

                        <italic toggle="yes">Am. J. Roentgenol.</italic>
</source>
                    <year>1978</year>;<volume>130</volume>:<fpage>651</fpage>&#x2013;<lpage>658</lpage>.
                    <pub-id pub-id-type="pmid">416673</pub-id>
                    <pub-id pub-id-type="doi">10.2214/ajr.130.4.651</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref6">
                <label>6</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Mashoof</surname>
                            <given-names>AA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Scholl</surname>
                            <given-names>MD</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Lahav</surname>
                            <given-names>A</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Osteochondral injury to the mid-lateral weight-bearing portion of the lateral femoral condyle associated with patella dislocation.</article-title>
                    <source>

                        <italic toggle="yes">Arthroscopy.</italic>
</source>
                    <year>2005</year>;<volume>21</volume>:<fpage>228</fpage>&#x2013;<lpage>232</lpage>.
                    <pub-id pub-id-type="pmid">15689874</pub-id>
                    <pub-id pub-id-type="doi">10.1016/j.arthro.2004.09.029</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref7">
                <label>7</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Enea</surname>
                            <given-names>D</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Busilacchi</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Cecconi</surname>
                            <given-names>S</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Late-diagnosed large osteochondral fracture of the lateral femoral condyle in an adolescent: a case report.</article-title>
                    <source>

                        <italic toggle="yes">J. Pediatr. Orthop. B.</italic>
</source>
                    <year>2013</year>;<volume>22</volume>:<fpage>344</fpage>&#x2013;<lpage>349</lpage>.
                    <pub-id pub-id-type="doi">10.1097/BPB.0b013e3283602650</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref8">
                <label>8</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Walsh</surname>
                            <given-names>SJ</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Boyle</surname>
                            <given-names>MJ</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Morganti</surname>
                            <given-names>V</given-names>
                        </name>
</person-group>:
                    <article-title>Large osteochondral fractures of the lateral femoral condyle in the adolescent: outcome of bioabsorbable pin fixation.</article-title>
                    <source>

                        <italic toggle="yes">J. Bone Joint Surg. Am.</italic>
</source>
                    <year>2008</year>;<volume>90</volume>:<fpage>1473</fpage>&#x2013;<lpage>1478</lpage>.
                    <pub-id pub-id-type="pmid">18594095</pub-id>
                    <pub-id pub-id-type="doi">10.2106/JBJS.G.00595</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref9">
                <label>9</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Stanitski</surname>
                            <given-names>CL</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Paletta</surname>
                            <given-names>GA</given-names>
                            <suffix>Jr</suffix>
                        </name>
</person-group>:
                    <article-title>Articular cartilage injury with acute patellar dislocation in adolescents. Arthroscopic and radiographic correlation.</article-title>
                    <source>

                        <italic toggle="yes">Am. J. Sports Med.</italic>
</source>
                    <year>1998</year>;<volume>26</volume>:<fpage>52</fpage>&#x2013;<lpage>55</lpage>.
                    <pub-id pub-id-type="doi">10.1177/03635465980260012501</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref10">
                <label>10</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Flachsmann</surname>
                            <given-names>R</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Broom</surname>
                            <given-names>ND</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Hardy</surname>
                            <given-names>AE</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Why is the adolescent joint particularly susceptible to osteochondral shear fracture?</article-title>
                    <source>

                        <italic toggle="yes">Clin. Orthop. Relat. Res.</italic>
</source>
                    <year>2000</year>;<volume>381</volume>:<fpage>212</fpage>&#x2013;<lpage>221</lpage>.
                    <pub-id pub-id-type="doi">10.1097/00003086-200012000-00025</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref11">
                <label>11</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Broom</surname>
                            <given-names>ND</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Oloyede</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Flachsmann</surname>
                            <given-names>R</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Dynamic fracture characteristics of the osteochondral junction undergoing shear deformation.</article-title>
                    <source>

                        <italic toggle="yes">Med. Eng. Phys.</italic>
</source>
                    <year>1996</year>;<volume>18</volume>:<fpage>396</fpage>&#x2013;<lpage>404</lpage>.
                    <pub-id pub-id-type="pmid">8818138</pub-id>
                    <pub-id pub-id-type="doi">10.1016/1350-4533(95)00067-4</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref12">
                <label>12</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Jabalameli</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Bagherifard</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Hadi</surname>
                            <given-names>H</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Osteochondral fracture in weight-bearing portion of lateral femoral condyle associated with patellar dislocation.</article-title>
                    <source>

                        <italic toggle="yes">J. Surg. Case Rep.</italic>
</source>
                    <year>2017</year>;<volume>2017</volume>(<issue>7</issue>):<fpage>rjx150</fpage>.
                    <pub-id pub-id-type="pmid">28775844</pub-id>
                    <pub-id pub-id-type="doi">10.1093/jscr/rjx150</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref13">
                <label>13</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Sanders</surname>
                            <given-names>TG</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Paruchuri</surname>
                            <given-names>NB</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Zlatkin</surname>
                            <given-names>MB</given-names>
                        </name>
</person-group>:
                    <article-title>MRI of osteochondral defects of the lateral femoral condyle: incidence and pattern of injury after transient lateral dislocation of the patella.</article-title>
                    <source>

                        <italic toggle="yes">AJR Am. J. Roentgenol.</italic>
</source>
                    <year>2006</year>;<volume>187</volume>(<issue>5</issue>):<fpage>1332</fpage>&#x2013;<lpage>1337</lpage>.
                    <pub-id pub-id-type="pmid">17056925</pub-id>
                    <pub-id pub-id-type="doi">10.2214/AJR.05.1471</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref14">
                <label>14</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Minas</surname>
                            <given-names>T</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Nehrer</surname>
                            <given-names>S</given-names>
                        </name>
</person-group>:
                    <article-title>Current concepts in the treatment of articular cartilage defects.</article-title>
                    <source>

                        <italic toggle="yes">Orthopedics.</italic>
</source>
                    <year>1997</year>;<volume>20</volume>(<issue>6</issue>):<fpage>525</fpage>&#x2013;<lpage>538</lpage>.
                    <pub-id pub-id-type="doi">10.3928/0147-7447-19970601-08</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref15">
                <label>15</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Asik</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Ciftci</surname>
                            <given-names>F</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Sen</surname>
                            <given-names>C</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: midterm results.</article-title>
                    <source>

                        <italic toggle="yes">Arthroscopy.</italic>
</source>
                    <year>2008</year>;<volume>24</volume>(<issue>11</issue>):<fpage>1214</fpage>&#x2013;<lpage>1220</lpage>.
                    <pub-id pub-id-type="pmid">18971050</pub-id>
                    <pub-id pub-id-type="doi">10.1016/j.arthro.2008.06.015</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref16">
                <label>16</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Schlechter</surname>
                            <given-names>JA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Nguyen</surname>
                            <given-names>SV</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Fletcher</surname>
                            <given-names>KL</given-names>
                        </name>
</person-group>:
                    <article-title>Utility of Bioabsorbable Fixation of Osteochondral Lesions in the Adolescent Knee: Outcomes Analysis With Minimum 2-Year Follow-up.</article-title>
                    <source>

                        <italic toggle="yes">Orthop. J. Sports Med.</italic>
</source>
                    <year>2019</year>;<volume>7</volume>:<fpage>2325967119876896</fpage>.
                    <pub-id pub-id-type="pmid">31696131</pub-id>
                    <pub-id pub-id-type="doi">10.1177/2325967119876896</pub-id>
                    <pub-id pub-id-type="pmcid">PMC6820181</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref17">
                <label>17</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>K&#x00fc;hle</surname>
                            <given-names>J</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Angele</surname>
                            <given-names>P</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Balcarek</surname>
                            <given-names>P</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Treatment of osteochondral fractures of the knee: a meta-analysis of available scientific evidence.</article-title>
                    <source>

                        <italic toggle="yes">Int. Orthop.</italic>
</source>
                    <year>2013</year>;<volume>37</volume>:<fpage>2385</fpage>&#x2013;<lpage>2394</lpage>.
                    <pub-id pub-id-type="pmid">24022737</pub-id>
                    <pub-id pub-id-type="doi">10.1007/s00264-013-2070-7</pub-id>
                    <pub-id pub-id-type="pmcid">PMC3843186</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref18">
                <label>18</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Bauer</surname>
                            <given-names>KL</given-names>
                        </name>
</person-group>:
                    <article-title>Osteochondral Injuries of the Knee in Pediatric Patients.</article-title>
                    <source>

                        <italic toggle="yes">J. Knee Surg.</italic>
</source>
                    <year>2018</year>;<volume>31</volume>:<fpage>382</fpage>&#x2013;<lpage>391</lpage>.
                    <pub-id pub-id-type="pmid">29381884</pub-id>
                    <pub-id pub-id-type="doi">10.1055/s-0038-1625956</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref19">
                <label>19</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Taitsman</surname>
                            <given-names>LA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Frank</surname>
                            <given-names>JB</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Mills</surname>
                            <given-names>WJ</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Osteochondral fracture of the distal lateral femoral condyle: a report of two cases.</article-title>
                    <source>

                        <italic toggle="yes">J. Orthop. Trauma.</italic>
</source>
                    <year>2006</year>;<volume>20</volume>:<fpage>358</fpage>&#x2013;<lpage>362</lpage>.
                    <pub-id pub-id-type="pmid">16766941</pub-id>
                    <pub-id pub-id-type="doi">10.1097/00005131-200605000-00011</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref20">
                <label>20</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Gkiokas</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Morassi</surname>
                            <given-names>LG</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Kohl</surname>
                            <given-names>S</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Bioabsorbable pins for treatment of osteochondral fractures of the knee after acute patella dislocation in children and young adolescents.</article-title>
                    <source>

                        <italic toggle="yes">Adv. Orthop.</italic>
</source>
                    <year>2012</year>;<volume>2012</volume>:<fpage>1</fpage>&#x2013;<lpage>4</lpage>.
                    <pub-id pub-id-type="doi">10.1155/2012/249687</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref21">
                <label>21</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Buckwalter</surname>
                            <given-names>JA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Brown</surname>
                            <given-names>TD</given-names>
                        </name>
</person-group>:
                    <article-title>Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis.</article-title>
                    <source>

                        <italic toggle="yes">Clin. Orthop. Relat. Res.</italic>
</source>
                    <year>2004</year>;<volume>423</volume>:<fpage>7</fpage>&#x2013;<lpage>16</lpage>.
                    <pub-id pub-id-type="doi">10.1097/01.blo.0000131638.81519.de</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref22">
                <label>22</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Gelber</surname>
                            <given-names>AC</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Hochberg</surname>
                            <given-names>MC</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Mead</surname>
                            <given-names>LA</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Joint injury in young adults and risk for subsequent knee and hip osteoarthritis.</article-title>
                    <source>

                        <italic toggle="yes">Ann. Intern. Med.</italic>
</source>
                    <year>2000</year>;<volume>133</volume>:<fpage>321</fpage>&#x2013;<lpage>328</lpage>.
                    <pub-id pub-id-type="pmid">10979876</pub-id>
                    <pub-id pub-id-type="doi">10.7326/0003-4819-133-5-200009050-00007</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref23">
                <label>23</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Braune</surname>
                            <given-names>C</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Rehart</surname>
                            <given-names>S</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Kerschbaumer</surname>
                            <given-names>F</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Resorbable pin refixation of an osteochondral fracture of the lateral femoral condyle due to traumatic patellar dislocation: case management, follow-up and strategy in adolescents.</article-title>
                    <source>

                        <italic toggle="yes">Z. Orthop. Ihre Grenzgeb.</italic>
</source>
                    <year>2004</year>;<volume>142</volume>(<issue>1</issue>):<fpage>103</fpage>&#x2013;<lpage>108</lpage>.
                    <pub-id pub-id-type="pmid">14968393</pub-id>
                    <pub-id pub-id-type="doi">10.1055/s-2004-817655</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref24">
                <label>24</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Fabricant</surname>
                            <given-names>PD</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Yen</surname>
                            <given-names>YM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Kramer</surname>
                            <given-names>DE</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Fixation of Chondral-only Shear Fractures of the Knee in Pediatric and Adolescent Athletes.</article-title>
                    <source>

                        <italic toggle="yes">J. Pediatr. Orthop.</italic>
</source>
                    <year>2017</year>;<volume>37</volume>:<fpage>156</fpage>.
                    <pub-id pub-id-type="pmid">28170363</pub-id>
                    <pub-id pub-id-type="doi">10.1097/BPO.0000000000000955</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref25">
                <label>25</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Visuri</surname>
                            <given-names>T</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Kuusela</surname>
                            <given-names>T</given-names>
                        </name>
</person-group>:
                    <article-title>Fixation of large osteochondral fractures of the patella with fibrin adhesive system. A report of two operative cases.</article-title>
                    <source>

                        <italic toggle="yes">Am. J. Sports Med.</italic>
</source>
                    <year>1989</year>;<volume>17</volume>:<fpage>842</fpage>&#x2013;<lpage>845</lpage>.
                    <pub-id pub-id-type="pmid">2624297</pub-id>
                    <pub-id pub-id-type="doi">10.1177/036354658901700621</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref26">
                <label>26</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Gul</surname>
                            <given-names>R</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Khan</surname>
                            <given-names>F</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Maher</surname>
                            <given-names>Y</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Osteochondral fractures in the knee treated with butyl-2-cyanoacrylate glue. A case report.</article-title>
                    <source>

                        <italic toggle="yes">Acta Orthop. Belg.</italic>
</source>
                    <year>2006</year>;<volume>72</volume>:<fpage>641</fpage>&#x2013;<lpage>643</lpage>.
                    <pub-id pub-id-type="pmid">17152432</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref27">
                <label>27</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Hsu</surname>
                            <given-names>TL</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Lin</surname>
                            <given-names>SM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Chang</surname>
                            <given-names>CH</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Neglected pediatric osteochondral fracture dislocation of the patella.</article-title>
                    <source>

                        <italic toggle="yes">Case Rep. Orthop.</italic>
</source>
                    <year>2019</year>;<volume>2019</volume>:<fpage>2904782</fpage>.</mixed-citation>
            </ref>
            <ref id="ref28">
                <label>28</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Nakayama</surname>
                            <given-names>H</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Yoshiya</surname>
                            <given-names>S</given-names>
                        </name>
</person-group>:
                    <article-title>Bone peg fixation of a large chondral fragment in the weight-bearing portion of the lateral femoral condyle in an adolescent: a case report.</article-title>
                    <source>

                        <italic toggle="yes">J. Med. Case Rep.</italic>
</source>
                    <year>2014</year>;<volume>8</volume>:<fpage>316</fpage>.
                    <pub-id pub-id-type="pmid">25248689</pub-id>
                    <pub-id pub-id-type="doi">10.1186/1752-1947-8-316</pub-id>
                    <pub-id pub-id-type="pmcid">PMC4177662</pub-id>
                </mixed-citation>
            </ref>
        </ref-list>
    </back>
    <sub-article article-type="reviewer-report" id="report396094">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.176952.r396094</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Soubih</surname>
                        <given-names>Hesham Ossama</given-names>
                    </name>
                    <xref ref-type="aff" rid="r396094a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r396094a1">
                    <label>1</label>Ain Shams University, Cairo, Cairo Governorate, Egypt</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>21</day>
                <month>8</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Soubih HO</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport396094" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.160982.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>1- The author presented the case plain X-ray in figure 1 with the comment "&#x00a0;Radiograph of the left knee showing no detectable abnormalities.". The plain X-ray shows a shell of bone separated from the lateral condyle in the lateral view. So, it is not correct to comment " no detectable abnormalities". The figure comment and other relevant data in the text should be revised.</p>
            <p> 2- In the discussion section, the author should mention the number or range of the osteochondral fractures incidence in the literature. This is important to justify presenting the case as a case report rather than a case series or any other study design</p>
            <p> 3- Regarding the management, the author used two headless metal screws. These screws can be at the level of the articular cartilage or better to be at the level of the subchondral bone. The screws are prominent in the X-ray. I understand why the author chose to leave the screws at the level of the articular cartilage because there is no sufficient subchondral bone to hold a secure fixation. At this case it is recommended to remove the screws to prevent cartilage damage. The author can not guarantee the survival of the cartilage around the screw head. It can be damaged by the initial trauma, the drill pit or future degenerative changes. A prominent screw can lead to unacceptable damage of the cartilage that may appear late in the X-ray after the compartment has ended in arthrosis, So as the author mentioned in the discussion, the screw should be removed.</p>
            <p> 4- In the discussion section: "Bioabsorbable pins offer the advantage of postoperative MRI compatibility. While multiple pins can enhance rotational stability, they may limit compression of the lesion. Screws, conversely, provide immediate compression and, when used in multiples, rotational stability." In the comparison, the authors should mention other disadvantages. For example, metal screws usually require another surgery for removal. Bioasbsorbable screws may lead to cystic changes.</p>
            <p>Are enough details provided of any physical examination and diagnostic tests, treatment given and outcomes?</p>
            <p>Yes</p>
            <p>Is the case presented with sufficient detail to be useful for other practitioners?</p>
            <p>Yes</p>
            <p>Is sufficient discussion included of the importance of the findings and their relevance to future understanding of disease processes, diagnosis or treatment?</p>
            <p>Yes</p>
            <p>Is the background of the case&#x2019;s history and progression described in sufficient detail?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Sports Medicine, Cartilage Reconstruction procedures.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
    </sub-article>
</article>
