<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="other" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.161537.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Policy Brief</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Enhancing post-road traffic orthopaedic injury rehabilitation to reduce disability in Rwanda: Policy brief</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 1 approved, 1 not approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Allen Ingabire</surname>
                        <given-names>JC</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
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                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8636-6473</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Stewart</surname>
                        <given-names>Aimee</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
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                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Sagahutu</surname>
                        <given-names>JB</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Urimubenshi</surname>
                        <given-names>Gerard</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0319-2912</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Bucyibaruta</surname>
                        <given-names>Georges</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
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                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Pilusa</surname>
                        <given-names>Sonti</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Uwakunda</surname>
                        <given-names>Carine</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Uwera</surname>
                        <given-names>Claudine</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Mugisha</surname>
                        <given-names>Didace</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a5">5</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Ingabire</surname>
                        <given-names>Leontine</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
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                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Tumusiime</surname>
                        <given-names>David</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
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                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Department of Surgery, University Teaching Hospital of Kigali, University of Rwanda, Kigali, Rwanda</aff>
                <aff id="a2">
                    <label>2</label>Physiotherapy Department, University of the Witwatersrand, Johannesburg, Gauteng, South Africa</aff>
                <aff id="a3">
                    <label>3</label>Physiotherapy Department, University of Rwanda, Kigali, Kigali City, Rwanda</aff>
                <aff id="a4">
                    <label>4</label>Department of Environmental, University of Rwanda, Kigali, Kigali City, Rwanda</aff>
                <aff id="a5">
                    <label>5</label>Center for Equity in Global Surgery, University of Global Health Equity, Kigali, Kigali City, Rwanda</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:ijea2000@gmail.com">ijea2000@gmail.com</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>3</day>
                <month>3</month>
                <year>2025</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>256</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>30</day>
                    <month>1</month>
                    <year>2025</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Allen Ingabire J et al.</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-256/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Prolonged disability resulting from road traffic injuries (RTIs) contributes significantly to morbidity and disease burden. A good understanding of the prevalence and the level of disability of orthopedic injuries in developing countries is crucial for improvement; however, such data are currently lacking in Rwanda.</p>
                </sec>
                <sec>
                    <title>Policy and implications</title>
                    <p>The goal of the policy is to address the growing number of road traffic injuries (RTIs) in Rwanda, with a focus on orthopaedic injuries that result in permanent disabilities. It suggests enhancing data collection and research, bolstering emergency response systems, growing rehabilitation services, offering victims social and financial support, and promoting inclusive policies. These programs may result in better emergency care, better rehabilitation outcomes, more informed interventions, lighter loads for victims and their families, more community support and awareness, and eventually a safer and more welcoming society for all Rwandans impacted by RTIs.</p>
                </sec>
                <sec>
                    <title>Recommendations</title>
                    <p>Rwanda&#x2019;s road traffic injuries (RTIs) are on the rise, and addressing this requires strengthening emergency response systems, expanding rehabilitation services, improving data collection, providing financial and social support, and advocating for inclusive policies. These measures aim to improve care, rehabilitation access, and foster a safer environment, reducing RTI burdens.</p>
                </sec>
                <sec>
                    <title>Conclusions</title>
                    <p>The conclusion underscores the urgent need for comprehensive action to tackle the high prevalence of road traffic orthopaedic injuries in Rwanda, emphasizing the need for enhanced emergency response, expanded rehabilitation services, and inclusive policies.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>: prevalence; disability; road traffic injuries; rehabilitation; WHODAS 2.0.</kwd>
                <kwd>policy brief</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1">
                    <funding-source>Consortium for Advanced Research Training in Africa (CARTA)</funding-source>
                </award-group>
                <award-group id="fund-2">
                    <funding-source>Developing Excellence in Leadership, Training and Science in Africa (DELTAS Africa)</funding-source>
                </award-group>
                <award-group id="fund-3" xlink:href="https://doi.org/10.13039/501100009497">
                    <funding-source>African Population and Health Research Center</funding-source>
                </award-group>
                <award-group id="fund-4">
                    <funding-source>UK Foreign, Commonwealth &amp; Development Office</funding-source>
                </award-group>
                <award-group id="fund-5">
                    <funding-source>Wellcome Trust</funding-source>
                    <award-id>107768/Z/15/Z</award-id>
                </award-group>
                <award-group id="fund-6">
                    <funding-source>Norwegian Agency for Development Cooperation (Norad)</funding-source>
                </award-group>
                <award-group id="fund-7">
                    <funding-source>Uppsala Monitoring Center</funding-source>
                </award-group>
                <award-group id="fund-8">
                    <funding-source>SIDA</funding-source>
                    <award-id>54100113</award-id>
                </award-group>
                <award-group id="fund-9" xlink:href="https://doi.org/10.13039/100017581">
                    <funding-source>University of Rwanda</funding-source>
                </award-group>
                <award-group id="fund-10">
                    <funding-source>Carnegie Corporation of New York</funding-source>
                    <award-id>G-19-57145</award-id>
                </award-group>
                <award-group id="fund-11">
                    <funding-source>University of the Witwatersrand</funding-source>
                </award-group>
                <funding-statement>This research was supported by the Consortium for Advanced Research Training in Africa (CARTA). CARTA is jointly led by the African Population and Health Research Center and the University of the Witwatersrand and funded by the Carnegie Corporation of New York (Grant No. G-19-57145), SIDA (Grant No:54100113), Uppsala Monitoring Center, Norwegian Agency for Development Cooperation (Norad), and by the Wellcome Trust [reference no. 107768/Z/15/Z] and the UK Foreign, Commonwealth &amp; Development Office, supported by the Developing Excellence in Leadership, Training and Science in Africa (DELTAS Africa) programme. The statements made and views expressed are solely the responsibility of the Fellow. &#13;
This research also was funded by the University of Rwanda through the SIDA open grant 2021-2023.</funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>Introduction</title>
            <p>In Rwanda, the surge of road traffic injuries (RTIs) poses a formidable public health challenge, significantly shaping the morbidity landscape of the nation (
                <xref ref-type="bibr" rid="ref7">Ingabire et al., 2024</xref>). These injuries often culminate in orthopedic damage which constitutes nearly half of all such events, with approximately 49% of these accidents leading to orthopedic complications. The sequelae of these injuries not only encompass immediate physical harm but also extend into prolonged or permanent disabilities, affecting a substantial 36% of the afflicted individuals (
                <xref ref-type="bibr" rid="ref1">Allen Ingabire et al., 2024a</xref>). Reference for Such outcomes severely impair quality of life, diminish economic productivity, and inhibit social integration, thus imposing a multifaceted burden on individuals and on the broader socioeconomic framework of Rwanda (
                <xref ref-type="bibr" rid="ref7">Ingabire et al., 2024</xref>; 
                <xref ref-type="bibr" rid="ref8">Allen Ingabire et al., 2024b</xref>).</p>
            <p>This escalating issue commands an urgent need for a detailed exploration and refinement of national policies concerning road safety, medical response, and rehabilitation practices. Therefore, our policy brief endeavors to elucidate the prevalence and implications of disabilities resulting from RTIs in Rwanda. Drawing upon recent empirical data, we advocate for robust, evidence-backed strategies aimed at mitigating the incidence of RTIs and enhancing the rehabilitation services post-injury. Through a comprehensive study, this brief not only seeks to spotlight the gravity and specifics of the issue but also to catalyze transformative changes in how these injuries are managed and prevented.</p>
            <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                <label>
Figure 1. </label>
                <caption>
                    <title>Average score of domains and WHODAS 2.0.</title>
                    <p>Among the 368 patients, the overall disability score of all domains was mild (22.9), the most affected domain was life activities with 26.46 and participation in life with 23.8 (
                        <xref ref-type="bibr" rid="ref1">Allen Ingabire et al., 2024</xref>).</p>
                </caption>
                <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/177577/2dc19dac-4cba-4d15-a3a1-c4f88f381cba_figure1.gif"/>
            </fig>
            <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                <label>
Figure 2. </label>
                <caption>
                    <title>Disability level according to the WHODAS 2.0 Domains.</title>
                    <p>Most participants post-traffic accident was not disabled in interpersonal skills (83%), communication (81%), self-care (66%), and mobility (53%), with severe disability in societal participation and life activities (28%) (
                        <xref ref-type="bibr" rid="ref1">Allen Ingabire et al., 2024</xref>).</p>
                </caption>
                <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/177577/2dc19dac-4cba-4d15-a3a1-c4f88f381cba_figure2.gif"/>
            </fig>
            <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                <label>
Figure 3. </label>
                <caption>
                    <title>Probability of disability vs Age group, Socioeconomic status, KTS and Rehabilitation.</title>
                    <p>The study reveals that the probability of having no disability is higher in younger individuals (36.9%), with milder cases (49%), moderator cases (9.8%), and severer cases (4.3%). The probability of disability increases with age (50-70 years), socioeconomic status (I), and with KTS. Rehabilitation improves moderate and severe disabilities (
                        <xref ref-type="bibr" rid="ref1">Allen Ingabire et al., 2024</xref>).</p>
                </caption>
                <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/177577/2dc19dac-4cba-4d15-a3a1-c4f88f381cba_figure3.gif"/>
            </fig>
            <table-wrap id="T1" orientation="portrait" position="float">
                <label>
Table 1. </label>
                <caption>
                    <title>Factors associated with disability (
                        <xref ref-type="bibr" rid="ref1">Allen Ingabire et al., 2024</xref>).</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top">Mild</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Moderate</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
Severe</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Age group</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">18-30</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">31-50</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.848(0.986-3.463)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.605(1.183-5.738)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.193(0.827-5.814)</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">&gt;50</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3.360(0.986-11.449)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3.778(0.902-15.824)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12.098(2.817-51.952)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Sex</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Male</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">Female</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.472(0.73-2.97)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.849(0.825-4.143)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.369(0.943-5.953)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Socio-economic status</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">I</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">II</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.711(0.276-10.617)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.547(0.084-3.549)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.579(0.082-4.077)</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">III</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.691(0.118-4.067)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.314(0.052-1.887)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.175(0.026-1.162)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Physiotherapy</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Yes</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ref</td>
                        </tr>
                        <tr>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">No</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.088(1.059-4.118)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">3.115(1.457-6.656)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">5.793(2.430-13.809)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>Length Hospital.Stay</bold>
</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.016(1.002-1.030)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.016(1.011-1.040)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.029(1.015-1.044)</td>
                        </tr>
                    </tbody>
                </table>
                <table-wrap-foot>
                    <p>All associated factors where independent variables of disability include age group, sex, socioeconomic status, KTS, rehabilitation and length of hospital stay. Age group and rehabilitation significantly predict disability, with patients over 50 years having 12 times more severe disabilities. Patients without rehabilitation were exposed to severe disability 5.7 times more.</p>
                </table-wrap-foot>
            </table-wrap>
        </sec>
        <sec id="sec6" sec-type="methods">
            <title>Methods</title>
            <p>

                <bold>Study design and setting:</bold> A cross-sectional analysis was adopted for this study, conducted across five major referral hospitals in Rwanda. This design was selected to capture a snapshot of the health outcomes and rehabilitation status of individuals who sustained Road Traffic-Related Orthopaedic Injuries (RTOI) in the year 2019.</p>
            <p>

                <bold>Participants:</bold> The study involved 368 adults who were victims of RTOI. These participants were identified from hospital records and included based on specific criteria: individuals aged 18 and over who had sustained injuries in traffic accidents in 2019 and had undergone or were undergoing treatment at one of the selected hospitals. Data was gathered two years post-injury, between June 2, 2022, and August 31, 2022. Participants filled out a series of detailed assessment forms to evaluate the functional outcomes of their injuries. This included the World Health Organization Disability Assessment Schedule (WHODAS 2.0) (
                <xref ref-type="bibr" rid="ref5">&#x00dc;st&#x00fc;n et al., 2010</xref>). Questionnaire to assess overall impairment levels, along with the Upper Extremity Functional Scale (UEFS) (
                <xref ref-type="bibr" rid="ref3">Pransky et al., 1997</xref>) and Lower-Extremity Functional Scale (LEFS) to specifically measure limb functionality (
                <xref ref-type="bibr" rid="ref4">Tumusiime et al., 2014</xref>). The data collected were analyzed using a combination of descriptive and inferential statistical techniques. The Chi-square test was utilized for categorical data to identify patterns and associations, while multinomial regression models helped explore the predictors of different disability outcomes. All analyses were performed using R Studio (
                <ext-link ext-link-type="uri" xlink:href="https://r4ds.hadley.nz/">https://r4ds.hadley.nz/</ext-link>), which provided robust tools for managing complex data sets and conducting extensive statistical evaluations.</p>
            <sec id="sec7">
                <title>Ethical consideration</title>
                <p>We obtained the ethical approval to conduct the study from the University of Rwanda College of Medicine and Health Sciences Institutional Review Board (18/CMHS IRB/2022) obtained on the 09 March 2022. The Rwanda National Research Committee operating in the Ministry of Health approved this study (NHRC/2022/PROT/014) obtained on 14 March 2022 and the collaboration with the Rwanda Biomedical Centre (5535/RBC/2022) injury department. We obtained the local ethical approvals from the five hospitals&#x2019; ethics committees: CHUK (EC/CHUK/051/2022) of the 30 March 2022, CHUB (REC/UTHB/089/2022) of the 21 March 2022, RH (313/RRH/DG/2022) of the 12 April 2022, KFH (EC/KFH/015/2022) of the 31 March 2022, RMH (RMH IRB/027/2022) of the 25 March 2022. All participants signed the consent form before enrolment into the study, and all data was kept confidential for only the study&#x2019;s purposes.</p>
            </sec>
            <sec id="sec8">
                <title>Policy outcomes and implications</title>
                <p>Given the substantial impact of road traffic-related orthopaedic injuries (RTIs) in Rwanda, which account for nearly half of all such incidents and often lead to long-term disabilities, it is imperative to adopt a multifaceted approach to both mitigate these injuries and enhance post-injury outcomes. The findings underscore a critical gap in rehabilitation services and a severe impact on societal participation and life activities, pointing to significant areas for policy intervention and systemic reform.</p>
            </sec>
            <sec id="sec9">
                <title>Actionable recommendations</title>
                <p>

                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>

                                <bold>Enhance Rehabilitation Services:</bold> Efforts must be intensified to close the 37.1% gap in rehabilitation services. This could be achieved through:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Infrastructure Development:</bold> Building or enhancing rehabilitation facilities to provide comprehensive care tailored to the severity of disabilities, ensuring geographic and economic accessibility for all.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Professional Training:</bold> Increasing investment in the training of healthcare professionals specializing in trauma and rehabilitation. This is crucial for improving the quality of care and support available to RTI victims.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Community-Based Programs:</bold> Developing community-based rehabilitation programs that extend care beyond hospital settings into the communities, making rehabilitation accessible and sustainable.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>2.</label>
                            <p>

                                <bold>Strengthen Emergency and Hospital Response:</bold> Rapid and effective emergency response can significantly reduce the severity of injuries from road traffic accidents:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Emergency Medical Services (EMS):</bold> Strengthen and expand EMS capabilities, including training for emergency responders and the establishment of more emergency call centers.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Hospital Preparedness:</bold> Enhance trauma care facilities within hospitals by upgrading equipment, increasing the number of specialized staff, and improving triage procedures to manage severe cases promptly and effectively.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>3.</label>
                            <p>

                                <bold>Policy and Regulatory Measures:</bold> Addressing the root causes of high RTI rates is fundamental to prevent these injuries in the first place:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Traffic Safety Laws:</bold> Implement stricter traffic regulations, enhance road safety measures, and promote rigorous enforcement of existing laws.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Public Awareness Campaigns:</bold> Launch comprehensive campaigns to educate the public on road safety practices, the importance of vehicle maintenance, and the severe impact of traffic injuries.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>4.</label>
                            <p>

                                <bold>Data and Research Development:</bold> An informed approach to policy-making necessitates robust data and continuous research:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Injury Surveillance Systems:</bold> Establish a national injury registry to monitor and analyze trends in road traffic injuries and their outcomes. This data will be crucial for policy development and evaluation.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Ongoing Research:</bold> Promote research into the causes, prevention, and treatment of RTIs to continually refine and update practices and policies.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>5.</label>
                            <p>

                                <bold>Financial and Social Support Systems:</bold> Victims of RTIs often face significant financial strains and social challenges:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Financial Aid Programs:</bold> Create financial assistance programs for victims of RTIs, helping mitigate the costs associated with long-term care and rehabilitation.</p>
                                    </list-item>
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Social Integration Programs:</bold> Develop initiatives aimed at reintegrating individuals with disabilities into society and the workforce, addressing both societal stigma and practical barriers.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>6.</label>
                            <p>

                                <bold>Advocacy and Legal Support</bold>:
                                <list list-type="bullet">
                                    <list-item>
                                        <label>&#x2022;</label>
                                        <p>

                                            <bold>Rights of the Disabled:</bold> Advocate for the rights of people with disabilities, ensuring legal protections are enforced and that comprehensive policies are in place to support their needs and rights.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                    </list>
                </p>
                <p>By deploying these integrated strategies, Rwanda can better manage the aftermath of RTIs and fundamentally lower their occurrence rate. Such policies not only reduce the physical and financial burden on affected individuals and their families but also contribute significant gains towards national health and economic stability.</p>
            </sec>
        </sec>
        <sec id="sec10" sec-type="conclusion|discussion">
            <title>Conclusion/Discussion</title>
            <p>The analysis undertaken in this study illuminates a growing crisis of orthopedic injuries stemming from road traffic accidents in Rwanda, where almost half of such incidents result in significant impairments. With an orthopedic injury rate at 49% and a consequential disability prevalence of 35.6%, the ramifications on public health and on socioeconomic structures are profound and far-reaching. The data not only reveal the extensive nature and severity of these disabilities but also highlight a distressing insufficiency of rehabilitation services; a critical 37.1% of the injured lack proper access to necessary rehabilitation, exacerbating the severity and prolongation of disabilities.</p>
            <p>Our findings establish a direct correlation between inadequate post-injury care and increased severity and persistence of disabilities, particularly affecting those in higher age brackets and individuals initially subjected to severe injuries. The study emphasizes the drastic disparity in outcomes for those receiving adequate rehabilitation versus those who do not, with those missing out on rehabilitation services experiencing considerably worse outcomes.</p>
        </sec>
        <sec id="sec11">
            <title>Ethical and consent</title>
            <p>We obtained the ethical approval to conduct the study from the University of Rwanda College of Medicine and Health Sciences Institutional Review Board (18/CMHS IRB/2022) obtained on the 09 March 2022. The Rwanda National Research Committee operating in the Ministry of Health approved this study (NHRC/2022/PROT/014) obtained on 14 March 2022 and the collaboration with the Rwanda Biomedical Centre (5535/RBC/2022) injury department. We obtained the local ethical approvals from the five hospitals&#x2019; ethics committees: CHUK (EC/CHUK/051/2022) of the 30 March 2022, CHUB (REC/UTHB/089/2022) of the 21 March 2022, RH (313/RRH/DG/2022) of the 12 April 2022, KFH (EC/KFH/015/2022) of the 31 March 2022, RMH (RMH IRB/027/2022) of the 25 March 2022. All participants signed the consent form before enrolment into the study, and all data was kept confidential for only the study&#x2019;s purposes.</p>
        </sec>
    </body>
    <back>
        <sec id="sec14" sec-type="data-availability">
            <title>Data availability</title>
            <p>Mendeley Data: Health Outcomes post RTI in Rwanda Data Set. 
                <ext-link ext-link-type="uri" xlink:href="https://www.doi.org/10.17632/h7v7sss84n.1">https://www.doi.org/10.17632/h7v7sss84n.1</ext-link>, (
                <xref ref-type="bibr" rid="ref6">Allen Ingabire, Jean de la Croix 2025</xref>)</p>
            <p>The project contains the following underlying data:
                <list list-type="order">
                    <list-item>
                        <label>1.</label>
                        <p>Health outcomes post-RTI in Rwanda Data.xlsx</p>
                    </list-item>
                </list>
            </p>
            <p>The data can also be accessed via the dataset titled &#x201c;Health Outcomes Following RTI in Rwanda&#x201d; by &#x201c;
                <xref ref-type="bibr" rid="ref6">Allen Ingabire, Jean de la Croix (2025)</xref>, &#x201c;Health Outcomes post RTI in Rwanda Data Set&#x201d;, Mendeley Data, V1, doi: 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.17632/h7v7sss84n.1">10.17632/h7v7sss84n.1</ext-link>&#x201d;. This dataset forms part of the comprehensive PhD work on health outcomes following road traffic injuries in Rwanda.</p>
            <p>Data are available under the terms of the 
                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
        </sec>
        <ack>
            <title>Acknowledgements</title>
            <p>I acknowledge everyone who supported and contributed to this study, especially the participants and research assistants from the five referral hospitals especially Joel Nshumuyiki, the chief research assistant. Special thanks go to my Supervisors for the PhD project entitled &#x201c;Health Outcomes of long-term disabilities following Road Traffic injuries in Rwanda&#x201d;.</p>
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                    <pub-id pub-id-type="doi">10.1080/17290376.2014.976249</pub-id>
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                            <surname>Chatterji</surname>
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                    <article-title>Developing the World Health Organization Disability Assessment Schedule 2.0.</article-title>
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                    <year>2010</year>;<volume>88</volume>(<issue>11</issue>):<fpage>815</fpage>&#x2013;<lpage>823</lpage>.
                    <pub-id pub-id-type="pmid">21076562</pub-id>
                    <pub-id pub-id-type="doi">10.2471/BLT.09.067231</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2971503</pub-id>
                </mixed-citation>
            </ref>
        </ref-list>
    </back>
    <sub-article article-type="reviewer-report" id="report378448">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.177577.r378448</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Groce</surname>
                        <given-names>Nora Ellen</given-names>
                    </name>
                    <xref ref-type="aff" rid="r378448a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r378448a1">
                    <label>1</label>University College London, London, England, UK</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>13</day>
                <month>5</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Groce NE</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport378448" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.161537.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This is a short but very solid article on the links between orthopaedic injury and rehabilitation to reduce disability in Rwanda.&#x00a0; This is written from the perspective of orthopaedic specialists, but the authors should be credited for bringing together orthopedics, rehabilitation and attention to the need for on-going care and support. I particularly liked the attention not just to clinical issues but also to community and disability concerns. These are often overlooked when discussing road traffic accidents.</p>
            <p> </p>
            <p> There are relatively few articles on this subject and even fewer from sub-Saharan Africa.&#x00a0; &#x00a0;As such, this paper represents a very nice addition to the literature.</p>
            <p> </p>
            <p> I think it stands well as is and I have no specific additional recommendations to make.&#x00a0; This is a thoughtful, tightly written paper and I'd like to see it accepted.</p>
            <p>Does the paper provide a comprehensive overview of the policy and the context of its implementation in a way which is accessible to a general reader?</p>
            <p>Yes</p>
            <p>Is the discussion on the implications clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>Are the recommendations made clear, balanced, and justified on the basis of the presented arguments?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Global health, international development, epidemiology, global disability, social science</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report378455">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.177577.r378455</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Rathore</surname>
                        <given-names>Farooq A.</given-names>
                    </name>
                    <xref ref-type="aff" rid="r378455a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-4759-0453</uri>
                </contrib>
                <aff id="r378455a1">
                    <label>1</label>Rehabilitation Medicine, National University of Medical Sciences, Rawalpindi, Punjab, Pakistan</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>8</day>
                <month>5</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Rathore FA</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport378455" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.161537.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>
                <bold>Summary and Overall Impression</bold>
            </p>
            <p> This policy brief addresses the burden of post-road traffic orthopaedic injuries (RTOIs) in Rwanda, emphasizing their substantial contribution to disability and socioeconomic disruption. It presents a compelling synthesis of original data from a cross-sectional study involving 368 individuals, analyzed using WHODAS 2.0 and functional outcome measures.</p>
            <p> The brief highlights key policy gaps and offers a six-pronged approach to address the rehabilitation and societal reintegration of RTI survivors. These include expansion of rehabilitation infrastructure, enhancement of emergency care, promotion of inclusive legislation, and investment in data systems and social support programs. The manuscript draws strength from locally relevant data and context-specific recommendations. However, there are many issues particularly in the methodology that need attention</p>
            <p> </p>
            <p> 
                <bold>Abstract</bold> 
                <list list-type="bullet">
                    <list-item>
                        <p>The abstract lacks structured headings which could improve clarity. Key numerical results from the study (e.g., prevalence, rehabilitation gap) are absent.</p>
                    </list-item>
                    <list-item>
                        <p>Authors should use a structured abstract format (Background, Methods, Findings, Policy Implications).</p>
                    </list-item>
                    <list-item>
                        <p>They should consider including 1&#x2013;2 key statistics to anchor the urgency of the issue.</p>
                    </list-item>
                </list> 
                <bold>&#x00a0;Methods</bold>
            </p>
            <p> 
                <bold>This section needs major attention and revisions</bold> 
                <list list-type="bullet">
                    <list-item>
                        <p>The study is based on robust data from five major Rwandan referral hospitals. However, it is not clear which five centers the authors are referring to? Are they public sector or private sector? Mention brief details about the centers, locations, capabilities and the justification on why they were selected</p>
                    </list-item>
                    <list-item>
                        <p>The use of WHODAS 2.0, UEFS, and LEFS provides multidimensional assessment of disability. However, it is important to know how these extensive questionnaires were administered? Who administered them or were they were filled by the respondents themselves? What was the language of these questionnaires? How much time did it take to fill in the questionnaires? Were these administered as paper or pen or online via a tablet?</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>The sampling strategy is insufficiently described; inclusion/exclusion criteria are scattered. Clearly describe the sampling method, response rate, and representativeness of the cohort.</p>
                    </list-item>
                    <list-item>
                        <p>There is a lack of clarity on potential bias (e.g., recall bias from retrospective data collection). Authors should discuss any limitations due to retrospective follow-up and how these were addressed</p>
                    </list-item>
                    <list-item>
                        <p>The rationale for choosing 2019 as the injury year is not explained. The authors should justify the temporal gap between injury and data collection.</p>
                    </list-item>
                </list> </p>
            <p> 
                <bold>Policy Recommendations and Implications</bold> 
                <list list-type="bullet">
                    <list-item>
                        <p>The policy recommendations are holistic, covering infrastructure, training, emergency care, law, data, and advocacy.</p>
                    </list-item>
                    <list-item>
                        <p>The structure into six actionable areas provides clarity and breadth.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>However, the prioritization of the recommendations is unclear and the readers may struggle to identify which interventions are most urgent. Include a prioritization framework (e.g., short-, medium-, and long-term actions).</p>
                    </list-item>
                    <list-item>
                        <p>Terminology like &#x201c;inclusive policies&#x201d; or &#x201c;KTS&#x201d; is not sufficiently explained. Please define technical terms and acronyms for a broader policy audience.</p>
                    </list-item>
                </list> 
                <bold>Discussion and Conclusion</bold> 
                <list list-type="bullet">
                    <list-item>
                        <p>The discussion section could elaborate more on generalizability beyond Rwanda.</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>There is little critical engagement with potential barriers to implementing recommendations (e.g., funding constraints, workforce limitations). Authors should briefly mention &#x00a0;lessons that might be transferable to other low- and middle-income countries (LMICs).</p>
                    </list-item>
                </list>
            </p>
            <p>Does the paper provide a comprehensive overview of the policy and the context of its implementation in a way which is accessible to a general reader?</p>
            <p>Partly</p>
            <p>Is the discussion on the implications clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>Are the recommendations made clear, balanced, and justified on the basis of the presented arguments?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Rehabilitation Medicine, Trauma Rehabilitation, Orthopedic Rehabilitation, Neurorehabilitation, Pain Medicine, Bioethics</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
    </sub-article>
</article>
