<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.165428.3</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Implementation of didactic strategies for assurance of learning with students at risk of academic failure in general chemistry</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 3; peer review: 3 approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Monsalve-Silva</surname>
                        <given-names>Santiago</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-4242-1773</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Bermudez-Aponte</surname>
                        <given-names>Jos&#x00e9; Javier</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Vera-Monroy</surname>
                        <given-names>Sulma Paola</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-7573-4151</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Engineering School, CAPSAB Research Group, Universidad de La Sabana, Campus del Puente del Com&#x00fa;n, km 7 Autopista Norte de Bogot&#x00e1;, Chia, Cundinamarca, 250001, Colombia</aff>
                <aff id="a2">
                    <label>2</label>Education School, Educaci&#x00f3;n y Educadores Research Group, Universidad de La Sabana, Campus del Puente del Com&#x00fa;n, km 7 Autopista Norte de Bogot&#x00e1;, Chia, Cundinamarca, 250001, Colombia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:sulmavemo@unisabana.edu.co">sulmavemo@unisabana.edu.co</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>27</day>
                <month>1</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>644</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>21</day>
                    <month>1</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Monsalve-Silva S et al.</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-644/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Assurance of Learning is a process focused on ensuring the quality and effectiveness of education. It involves implementing practices, policies, and procedures intended to ensure the development of skills, competencies, and knowledge expected in a specific educational program or course. In the subjects Chemistry and General Chemistry I at the Universidad de La Sabana, persistent issues with low academic performance have resulted in rising course repetition rates, lack of motivation, and student dropout.</p>
                </sec>
                <sec>
                    <title>Methods</title>
                    <p>The present study examines targeted didactic strategies for students at risk of academic failure in these subjects, representing an innovation in the field of education and contributing to the domain of learning assurance in Chemistry. It was conducted under a mixed-methods approach with a quasi-experimental and cross-sectional design. A predictive trend analysis was carried out, and strategies were identified, selected, and implemented with consideration for students&#x2019; perceptions and assessments. Two samples were analyzed: a characterization sample of 411 students who took the subjects between the second semester of 2020 and the first semester of 2023, and an experimental sample comprising students from the second semester of 2023 and the first semester of 2024.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>The results revealed that participation in the implemented strategies led to improved academic performance, particularly for students with lower Saber 11 scores. Strategy 1 (leveling course) showed the greatest positive impact, with statistically significant differences in performance. Moreover, students reported high satisfaction with the strategies, especially regarding their usefulness, engagement, and relevance.</p>
                </sec>
                <sec>
                    <title>Conclusions</title>
                    <p>These findings suggest that personalized and contextualized didactic strategies are effective in supporting students at risk of academic failure in general chemistry courses.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Chemistry teaching</kwd>
                <kwd>Higher Education</kwd>
                <kwd>Learning strategy</kwd>
                <kwd>Chemistry</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1">
                    <funding-source>Universidad de La Sabana</funding-source>
                    <award-id>ING-303-2022</award-id>
                </award-group>
                <funding-statement>This project was financed by Direcci&#x00f3;n General Investigaci&#x00f3;n de la Universidad de La Sabana, project code ING-303-2022, &#x201c;Artificial intelligence: a management tool for learning assurance in basic science subjects in engineering programs&#x201d;.</funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
        <notes>
            <sec sec-type="version-changes">
                <label>Revised</label>
                <title>Amendments from Version 2</title>
                <p>In this revised version, we streamlined the Introduction to improve clarity and flow, reducing redundancy and sharpening the central rationale for the study. We also added a concise summary table describing the didactic strategies. In addition, we standardized figure and table labeling across the manuscript and revised figure/table captions to ensure consistency and conciseness.</p>
            </sec>
        </notes>
    </front>
    <body>
        <sec id="sec1" sec-type="intro">
            <title>1. Introduction</title>
            <p>At university level, the teaching of chemistry remains highly relevant as this fundamental science provides students with the knowledge needed to understand the living and physical environment and to connect science, technology, and society, ultimately promoting scientific competencies.
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>
                </sup> Basic science courses underpin professional training disciplines by providing a foundational knowledge base. Riza et al.,
                <sup>
                    <xref ref-type="bibr" rid="ref3">2</xref>
                </sup> Uriel et al.,
                <sup>
                    <xref ref-type="bibr" rid="ref2">3</xref>
                </sup> and Xeidakis
                <sup>
                    <xref ref-type="bibr" rid="ref4">4</xref>
                </sup> have emphasized that these courses underpin professional training by building the conceptual foundation required to integrate technology, solve problems, and respond to 21
                <sup>st</sup>-century challenges. In engineering education, the ability to apply foundational knowledge is one of the most important learning outcomes and, indeed, is recognized as the primary learning outcome by the Accreditation Board for Engineering and Technology (ABET).</p>
            <p>Nevertheless, chemistry and other basic sciences are often perceived by students as complex and difficult to understand. Cardellini
                <xref ref-type="bibr" rid="ref5">
                    <sup>5</sup>
                </xref> highlights that chemistry involves working with invisible and intangible phenomena, which makes comprehension highly abstract. These challenges can undermine academic performance and are frequently associated with high failure rates, demotivation and, dropout. According to Am&#x00e9;stica-Rivas et al.,
                <xref ref-type="bibr" rid="ref6">
                    <sup>6</sup>
                </xref> this situation also imposes a significant burden on stakeholders in the learning process, including families, students, and educational institutions.</p>
            <p>Chemistry the science that studies substances and their interactions, focusing on matter, energy, and their transformations
                <xref ref-type="bibr" rid="ref7">
                    <sup>7</sup>
                </xref>
                <sup>,</sup>
                <xref ref-type="bibr" rid="ref8">
                    <sup>8</sup>
                </xref> is a conceptual pillar for disciplines such as engineering, health sciences, agricultural sciences, veterinary science, physics, and education. Its contributions to society are evident in developments in food production, health products, and plastics that support daily life.
                <xref ref-type="bibr" rid="ref9">
                    <sup>9</sup>
                </xref>
                <sup>,</sup>
                <xref ref-type="bibr" rid="ref10">
                    <sup>10</sup>
                </xref> However, despite its relevance, a major challenge in chemistry education is the heterogeneity of students&#x2019; prior preparation upon entering higher education. According to Carrillo et al.,
                <xref ref-type="bibr" rid="ref11">
                    <sup>11</sup>
                </xref> and Kumari et al.
                <xref ref-type="bibr" rid="ref12">
                    <sup>12</sup>
                </xref> while some students arrive with a strong foundation in fundamental chemistry concepts and the tools needed for academic success, others possess minimal or no prior knowledge. Furi&#x00f3;-Mas et al.
                <xref ref-type="bibr" rid="ref13">
                    <sup>13</sup>
                </xref> and D&#x00ed;az et al.
                <xref ref-type="bibr" rid="ref14">
                    <sup>14</sup>
                </xref> note that insufficient basic knowledge and skills becomes a critical barrier, because these are prerequisites for mastering more complex concepts.</p>
            <p>When limited prior preparation is combined with the high level of abstraction required to understand chemical phenomena, students often show low performance in foundational courses, which can lead to demotivation, repetition and dropout. Reyes et al.
                <xref ref-type="bibr" rid="ref15">
                    <sup>15</sup>
                </xref> report that many students repeat such courses two or more times, delaying the completion of their studies and diminishing their academic enthusiasm. Furthermore, Espitia et al.,
                <xref ref-type="bibr" rid="ref16">
                    <sup>16</sup>
                </xref> Molina et al.,
                <xref ref-type="bibr" rid="ref17">
                    <sup>17</sup>
                </xref> and Vera-Monroy and Monsalve-Silva
                <xref ref-type="bibr" rid="ref18">
                    <sup>18</sup>
                </xref> indicate that Colombian students frequently perceive chemistry as abstract, difficult, and lacking practical relevance, which contributes to negative attitudes and apathy toward the subject, despite its importance for interpreting phenomena in their environments and professional fields.</p>
            <p>At the national level in Colombia, the Ministry of National Education is tasked with increasing access to education and reducing student dropout rates. To achieve this, it collaborates closely with higher education institutions (HEIs) to foster student retention and ensure degree completion. University dropout is a common problem in many countries that has garnered significant attention in academic research.
                <sup>
                    <xref ref-type="bibr" rid="ref19">19</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref21">21</xref>
                </sup> Studies have identified various influencing factors, including sociocultural, economic, and political conditions; study environments; academic and social integration; personal effort and motivation; students&#x2019; sociodemographic backgrounds; and external circumstances.
                <sup>
                    <xref ref-type="bibr" rid="ref22">22</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref24">24</xref>
                </sup> As Rueda et al.
                <sup>
                    <xref ref-type="bibr" rid="ref25">25</xref>
                </sup> and Cigdem et al.
                <sup>
                    <xref ref-type="bibr" rid="ref26">26</xref>
                </sup> argue, dropout negatively impacts both students&#x2019; futures and the development and growth of society as a whole.</p>
            <p>Among the academic determinants of dropout, course repetition, low academic performance, poor comprehension, ineffective teaching methodologies, and insufficient prior preparation have been shown to hinder the development of the skills necessary for academic success.
                <sup>
                    <xref ref-type="bibr" rid="ref27">27</xref>
                </sup> These difficulties are particularly visible in STEM (Science, Technology, Engineering, and Mathematics) fields, where performance gaps between students are increasingly evident.
                <sup>
                    <xref ref-type="bibr" rid="ref28">28</xref>
                </sup> Researchers attribute these disparities to both curricular and disciplinary causes. In the case of chemistry, its nature&#x2014;together with issues in classroom practices, curriculum design, teacher training, and students&#x2019; adaptation to the university environment&#x2014;makes it a particularly demanding subject.
                <sup>
                    <xref ref-type="bibr" rid="ref29">29</xref>
                </sup>
            </p>
            <p>Therefore, educational institutions (EIs) must implement intentional processes to promote academic success, connect chemistry learning with practical relevance, and foster the knowledge and skills required for professional competence.
                <xref ref-type="bibr" rid="ref30">
                    <sup>30</sup>
                </xref> Although institutions employ strategies to promote learning and skills development,
                <xref ref-type="bibr" rid="ref31">
                    <sup>31</sup>
                </xref> these efforts are often designed for the general student population and may not sufficiently address the needs of students at risk of academic failure.</p>
            <p>At the Universidad de La Sabana, undergraduate programs in the Faculty of Engineering, including Industrial, Civil, Mechanical, Chemical, and Bioproduction Engineering, incorporate chemistry courses as part of their basic curriculum. In General Chemistry I, between the 2020-2 and 2023-1 academic periods, low academic performance on partial exams was associated with high failure and increasing dropout, pass rates decreased across assessment periods (54.9%, 43.2%, and 38.0%); while failure rates remained high (43.6%, 53.1%, and 53.6%); and dropout rose notably (1.5%, 3.7%, and 8.4%). Similarly, in Chemistry, between the 2022-1 and 2023-1 periods, pass rates were 53.5%, 36.4%, and 49.7%; failure rates were 45.5%, 58.8%, and 43.9%; and dropout rates were 1.1%, 4.8%, and 6.4%.</p>
            <p>Given the challenges of low academic performance in Chemistry and General Chemistry I courses at the Universidad de La Sabana &#x2013; reflected in repetition, demotivation, and dropout- the present study, conducted as part of the project &#x201c;Artificial Intelligence: A Management Tool for Assurance of Learning in Basic Science Courses in Engineering Programs&#x201d;, sought to develop and examine learning strategies aimed at fostering academic success among students at risk of failure in these courses, offered by the Department of Chemical and Biotechnological Processes. Specifically, the study addressed the following question: How can the learning of students classified by the Saber 11 tests as at risk of academic failure in the courses Chemistry and General Chemistry I within the engineering programs at the Universidad de La Sabana be ensured through the implementation of didactic strategies?</p>
        </sec>
        <sec id="sec2">
            <title>2. Background</title>
            <sec id="sec3">
                <title>2.1 Assurance of learning</title>
                <p>Assurance of Learning (AoL) is not merely an isolated initiative within educational institutions; rather, it represents a fundamental system for achieving educational objectives, positioned as a central activity in higher education and enhanced by national and international accreditation processes, which involve continuous monitoring of students&#x2019; progress throughout their educational programs.
                    <sup>
                        <xref ref-type="bibr" rid="ref32">32</xref>
                    </sup> Its impact is evident in both academic success and the overall quality of education.
                    <sup>
                        <xref ref-type="bibr" rid="ref33">33</xref>
                    </sup> In the AoL process, decisions are made, and improvements are implemented, as noted by Kokku (2021).
                    <sup>
                        <xref ref-type="bibr" rid="ref34">34</xref>
                    </sup> Therefore, to carry out AoL effectively, educational programs must clearly define their learning outcomes and design targeted strategies to achieve them. In most cases, the primary responsibility for implementing AoL falls on educators, who execute various strategies intended to promote learning and, thereby, academic success.</p>
                <p>In the current educational landscape, technology has had a marked impact on the development and implementation of AoL processes. Poveda-Pineda and Cifuentes-Medina
                    <sup>
                        <xref ref-type="bibr" rid="ref35">35</xref>
                    </sup> emphasize how the adoption of innovative technologies has revolutionized the establishment and monitoring of processes within educational program projects (PEPs). Furthermore, AoL demands a shift in perspective from an internal to an external view of learning efficacy and accountability. Institutions are increasingly focused on demonstrating accountability to the public, ensuring educational quality aligned with graduate profiles, meeting accreditation and legislative requirements, and facilitating continuous improvement and institutional decision-making.
                    <sup>
                        <xref ref-type="bibr" rid="ref36">36</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec4">
                <title>2.2 Academic performance</title>
                <p>There are multiple interpretations of academic performance, though generally, according to Torres et al.,
                    <sup>
                        <xref ref-type="bibr" rid="ref37">37</xref>
                    </sup> these often depend on outcomes from the educational process, manifested in achievements attained as evaluated on the basis of regularly established criteria. Thus, evaluation processes are fundamental to understanding academic performance, as they provide information on the relative achievement of learning objectives.
                    <sup>
                        <xref ref-type="bibr" rid="ref38">38</xref>
                    </sup> Nonetheless, it is essential to recognize that academic performance is influenced by various factors, such as economic, social, and family contexts; motivation; the university environment; and students&#x2019; cognitive abilities.
                    <sup>
                        <xref ref-type="bibr" rid="ref39">39</xref>
                    </sup>
                </p>
                <p>Academic performance plays a crucial role in decision-making within teaching and learning processes. Several studies have shown that dropout rates are higher in the first year of university than in subsequent years (e.g., van Rooij et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref40">40</xref>
                    </sup>). Therefore, monitoring student performance during this period, particularly, can help identify opportunities for improvement and support the achievement of established goals within the academic process&#x2014;namely, learning outcomes.</p>
                <p>Finally, evaluating a training process&#x2019;s effectiveness can be approached from two distinct perspectives. The first, an objective perspective, is that of academic performance, which encapsulates the synthesis of attributes related to the quality of educational experience resulting from the interaction of cognitive processes.
                    <sup>
                        <xref ref-type="bibr" rid="ref41">41</xref>
                    </sup> The other, a subjective perspective, is based on individual student perceptions. It is worth noting that both these perspectives are influenced by contextual factors, such as family, self-esteem, gender, marital status, and study habits.
                    <sup>
                        <xref ref-type="bibr" rid="ref42">42</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec5">
                <title>2.3 General performance in basic sciences in universities and engineering faculties</title>
                <p>Basic sciences serve as a structural foundation of knowledge that enables a deep and critical understanding of the world around us. Their value lies in providing essential conceptual and methodological frameworks for interpreting natural, social, and technological phenomena&#x2014;indispensable assets in an increasingly complex global landscape. Through these disciplines, one can better understand the interactions between human and natural systems and anticipate the impacts of emerging issues such as climate change, energy transitions, and public health challenges. Moreover, basic sciences equip future generations with the intellectual and scientific tools needed to address not only current problems but also as yet unrecognized ones.
                    <sup>
                        <xref ref-type="bibr" rid="ref44">44</xref>
                    </sup>
                </p>
                <p>Student retention in STEM disciplines is essential for societal development; however, it also presents a significant challenge for universities. Alarmingly, a considerable number of students who initially enroll in STEM programs choose to drop out or switch to other fields of study by their second year in university, as noted by Gupta and Hartwell.
                    <sup>
                        <xref ref-type="bibr" rid="ref29">29</xref>
                    </sup> This trend raises critical questions about how to sustain student interest in and engagement with science, technology, engineering, and mathematics, highlighting the need to implement effective strategies that foster greater retention and academic success in these areas.</p>
                <p>In Colombia, the Colombian Association of Engineering Faculties (ACOFI, by its acronym in Spanish) has, since 2007, placed a focus on assessing engineering students&#x2019; competencies and learning outcomes. This effort relies on collecting reliable data on basic sciences through the Basic Sciences Enrollment Exam, which evaluates student performance in key areas such as mathematics, physics, chemistry and biology; provides valuable information on the quality of engineering education; and ensures adequate national standards for the training of future engineers.
                    <sup>
                        <xref ref-type="bibr" rid="ref45">45</xref>
                    </sup> To date, more than 22,500 Colombian students have taken the exam, with 20 HEIs participating in its most recent application (2022). Exam data provides valuable indicators for both instructors and those overseeing quality assurance processes. It not only helps identify strengths and weaknesses in teaching and learning processes but also serves to promote the review and analysis of microcurricula, highlighting areas that require greater attention and development.</p>
                <p>According to the data presented in the EXIM inform, in the year 2021, the average score for biology decreased from 54.40 to 51.40, in comparison with that of 2020, though the general scores for the other areas increased: mathematics rose from 47.25 to 49.45, physics from 40.35 to 49.30, and chemistry from 40.44 to 52.00. However, by 2022, the average score for chemistry had decreased to 50.41. The exam assessed competencies such as abstraction, analysis, and synthesis; applying knowledge in practice; and identifying, formulating, and solving problems. The results reveal that while students demonstrated abilities to analyze information requiring basic chemical knowledge, they struggled to establish analyses and correlations with underlying scientific knowledge. Additionally, students showed a solid theoretical understanding of interpretative models for physicochemical changes but faced challenges in establishing mathematical relationships between the parameters describing those changes. Lastly, although students were able to identify the constituent elements of a problem, they encountered difficulties in effectively connecting these elements to physicochemical concepts, leading to weak mathematical interpretation in their academic performance.
                    <sup>
                        <xref ref-type="bibr" rid="ref45">45</xref>
                    </sup> Consequently, 52.1% of students were classified at a low level on the Chemistry evaluation scale.</p>
            </sec>
            <sec id="sec6">
                <title>2.4 Institutional actions to achieve academic success</title>
                <p>Universities today play a crucial role in fostering knowledge acquisition aimed at solving contextualized problems. Institutions must adopt educational models that prioritize learning over traditional teaching, which has often been characterized by mechanistic actions and rote memorization. These models must contribute significantly to the development of professionals capable of leading sustainable transformations in their respective regions, emphasizing holistic education and human development. In a world marked by increasing complexity and dynamism, teaching centered solely on content is no longer sufficient.</p>
                <p>Instead, universities should adopt competency-based education, which emphasizes a combination of knowledge, skills, and attitudes that help professionals to respond effectively to specific needs.
                    <sup>
                        <xref ref-type="bibr" rid="ref46">46</xref>
                    </sup> This shift requires a solid theoretical foundation, the formulation of new pedagogical objectives that embrace diversity, and the implementation of methods, approaches, and educational strategies that empower students to take ownership of their learning processes. Such an approach prepares students to adapt to different environments and trust their critical reasoning abilities. Ultimately, this paradigm fosters humanization in a world with no singular model of humanity, but rather a rich diversity of perspectives and experiences that deserve recognition and respect.
                    <sup>
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>
                    </sup>
                </p>
                <p>Consequently, the traditional role of the professor as a mere transmitter of knowledge is being redefined. Professors are now expected to serve as guides and facilitators, helping students construct frameworks for understanding and interpretation that transform information into knowledge. This redefinition promotes autonomous learning, the capacity to learn how to learn, and lifelong learning, along with competency development. Pedagogical strategies have evolved to encourage integral learning, with Information and Communication Technologies (ICTs) serving as innovative tools for educational transformation and the humanization of learning processes.
                    <sup>
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref49">49</xref>
                    </sup>
                </p>
                <p>In this evolving context of the professor&#x2019;s role and educational transformation, AoL has emerged as a central pillar of academic activity. The quality and relevance of education, particularly in management and business, have come under increasing scrutiny from various stakeholders, including students, employers, media, and educators.
                    <sup>
                        <xref ref-type="bibr" rid="ref32">32</xref>
                    </sup> AoL serves as a vital tool for assessing and enhancing the effectiveness of the educational process in this dynamic and demanding environment.</p>
            </sec>
            <sec id="sec7">
                <title>2.5 Strategies to foster assurance of learning</title>
                <p>AoL, conceived as a process aimed at monitoring or demonstrating achievement in educational processes, requires careful planning, justification, and execution of curricular and pedagogical activities tailored to individual students&#x2019; needs while aligning with the required competencies and knowledge to be developed.
                    <sup>
                        <xref ref-type="bibr" rid="ref50">50</xref>
                    </sup> Such activities, however, are not always the same even within a specific course, nor does the same strategy suit all students, highlighting the need to adapt and personalize AoL processes to meet the diverse demands of learners.</p>
                <p>Research has explored extracurricular strategies, which extend beyond the classroom, to strengthen AoL. Among these, peer learning has emerged as a fundamental approach, recognized for its effectiveness in helping students build confidence in their abilities and take active roles in their learning processes. Peer learning promotes mutual collaboration in teaching, yielding significant benefits for academic development.
                    <sup>
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>
                    </sup> One peer-based strategy involves personalized student support through counseling, mentoring, or academic advising.
                    <sup>
                        <xref ref-type="bibr" rid="ref53">53</xref>
                    </sup> Online peer learning environments leveraging existing technologies can enhance academic performance and motivate students, and Razak &amp; See
                    <sup>
                        <xref ref-type="bibr" rid="ref54">54</xref>
                    </sup> emphasize that such environments provide a conducive space for scaffolding the learning process through engaging activities that foster both academic success and motivation. In-person programs have also been shown to be effective, such as a mentoring program implemented by Yusta-Loyo et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref55">55</xref>
                    </sup> at the University of Zaragoza that promoted collaboration between senior students and new entrants while maintaining continuous academic support from professors across different subjects. In addition to such peer-learning strategies, the value of learning communities focused on specific topics&#x2014;alternatively known as focus groups&#x2014;has also been recognized.
                    <sup>
                        <xref ref-type="bibr" rid="ref53">53</xref>
                    </sup> Learning communities facilitate collaborative knowledge construction and the development of high-level skills.
                    <sup>
                        <xref ref-type="bibr" rid="ref56">56</xref>
                    </sup>
                </p>
                <p>To enhance student participation and empowerment in their learning processes, various pedagogical and didactic strategies have been implemented, including the use of graphic organizers, virtual classes, and independent workshops. An illustrative example of these practices is presented by Bolton-King,
                    <sup>
                        <xref ref-type="bibr" rid="ref57">57</xref>
                    </sup> who designed workshop-based focus groups. In this approach, mentors received detailed lesson plans for each workshop, and through guided questions, they fostered reflection and debate among students. This created a collaborative environment and encouraged constructive peer feedback, thereby strengthening the learning process. Several studies have addressed strategies to ensure learning, including,
                    <sup>
                        <xref ref-type="bibr" rid="ref58">58</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref61">61</xref>
                    </sup> who developed approaches in mentoring, coaching, and extracurricular academic advising. These strategies, based on diverse didactic principles, were implemented in both virtual and in-person learning environments. The findings reflect the diversity of approaches that can contribute to academic success and the formative growth of students. Finally, research on the design and implementation of academic leveling courses has demonstrated their relevance for strengthening foundational knowledge or specific areas critical to student development across various disciplines, including mathematics, programming, and English.
                    <sup>
                        <xref ref-type="bibr" rid="ref53">53</xref>
                    </sup>
                </p>
            </sec>
            <sec id="sec8">
                <title>2.6 Standardized national exams</title>
                <p>In Colombia, the responsibility for administering standardized national exams, intended to evaluate the quality of education at various levels, lies with the Colombian Institute for Educational Evaluation (ICFES), as established by Law 1324 of 2009.
                    <sup>
                        <xref ref-type="bibr" rid="ref62">62</xref>
                    </sup> This law also assigns the task of defining what content is to be assessed in these exams to the Ministry of National Education (MEN).
                    <sup>
                        <xref ref-type="bibr" rid="ref63">63</xref>
                    </sup> Currently, ICFES oversees various exams, including Saber 3&#x00b0;, Saber 5&#x00b0;, Saber 9&#x00b0;, and Saber 11&#x00b0;, which evaluate the quality of primary and secondary education. Additionally, the Saber Pro exam is used to assess the quality of higher education.</p>
                <p>The Saber 11&#x00b0; exam is conducted at the end of eleventh grade to provide an official assessment of the quality of formal education amongst students completing secondary school. Moreover, under current regulations (ICFES, 2023), this exam can also be taken by individuals who have already obtained a high school diploma or have passed a high school validation test. The objectives of the Saber 11&#x00b0; exam, as stipulated in Decree 869 of 2010, are summarized in 
                    <xref ref-type="fig" rid="f1">
Figure 1</xref>.</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>
Figure 1. </label>
                    <caption>
                        <title>Objectives of the Saber 11&#x00b0; test.</title>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure1.gif"/>
                </fig>
                <p>The Saber 11&#x00b0; exam comprises five components derived from the competencies outlined in the fundamental skill standards established by the MEN:
                    <sup>
                        <xref ref-type="bibr" rid="ref64">64</xref>
                    </sup> critical reading, mathematics, social sciences, natural sciences, and English. The natural sciences competencies contemplate students&#x2019; abilities to understand science as a universal and evolving discipline capable of explaining and predicting natural phenomena, as well as the conception of science as a dynamic human construct encompassing both theoretical and practical aspects, whose development is closely tied to evolving relationships between science, technology, and society.
                    <sup>
                        <xref ref-type="bibr" rid="ref63">63</xref>
                    </sup> In accordance with ICFES (2022) guidelines, the natural sciences component of the Saber 11&#x00b0; exam assesses students&#x2019; ability to understand and apply notions, concepts, and theories related to the natural sciences to solve problems. It also evaluates students&#x2019; capacities to explain how certain natural phenomena can occur based on observations, patterns, and scientific knowledge. The evaluation incorporates the inquiry process, which involves observation and pattern identification in data to deduce conclusions about natural phenomena.</p>
                <p>Research has identified several statistically significant factors associated with strong academic performance in the Saber 11&#x00b0; exams, which include medium or high socioeconomic status, study schedules, access to ICTs (measuring students&#x2019; ability to use the internet, computers, and telephony from home), and parental education levels.
                    <sup>
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>
                    </sup>
                </p>
            </sec>
        </sec>
        <sec id="sec9">
            <title>3. Methodology</title>
            <sec id="sec10">
                <title>3.1 Methodology design</title>
                <p>The present study used a mixed approach with an embedded concurrent dominant model design (DIAC), also known as an integrated design,
                    <sup>
                        <xref ref-type="bibr" rid="ref67">67</xref>
                    </sup> to collect both quantitative and qualitative data simultaneously or sequentially. In such a design, one type of data supports the other
                    <sup>
                        <xref ref-type="bibr" rid="ref68">68</xref>
                    </sup>; in the present study, qualitative data were used to support explanations based on quantitative data. The research design was quasi-experimental in that participating students were selected based on academic criteria rather than randomly.
                    <sup>
                        <xref ref-type="bibr" rid="ref69">69</xref>
                    </sup> Finally, the study followed a cross-sectional correlational-causal approach, in which relationships between categories (in this case, the relationship between academic performance and the implementation of the strategies) were described at a specific point in time.</p>
            </sec>
            <sec id="sec11">
                <title>3.2 Population and sample</title>
                <p>The study was conducted using academic and characterization data on cognitive styles, perception channels, and metacognitive skills of students enrolled in the subjects Chemistry and General Chemistry I during the academic periods from 2020-2 to 2023-1, totaling 411 students who served as the control group. The study sample consisted of students enrolled in the engineering school programs during the 2023-2 and 2024-1 periods, comprising 60 students identified as being at risk of academic failure in the same two subjects, as selected through predictive trend analysis.</p>
                <p>In total, 144 students enrolled in the 2023-2 period and 178 students in the 2024-1 period. Across both periods, 60 students were identified as being at risk of academic failure. Of these, 15 participated only in the course component, 12 only in the kit component, and 33 completed both. The sample sizes were determined by voluntary student participation; consequently, no exhaustive control over participation was applied, in order to minimize potential risks and avoid any perception that involvement in the study was mandatory.</p>
                <p>All participants received informed consent and were presented with the project, explaining their participation. For participants who were minors, a certificate was sent to their parents or guardians along with project information. All participants who agreed signed the written consent.</p>
                <p>Students were classified as at risk when their overall score on the Saber 11&#x00b0; test or their score on the critical reading, natural sciences, and mathematics components was related to a rating of less than 3.0 in the subject&#x2019;s performance, which previous institutional analyses had correlated with a probability of more than 60% of failing Chemistry or General Chemistry I. This identification was verified through a predictive trend analysis using historical data from the 2020-2 academic year to the 2023-1 academic year.</p>
            </sec>
            <sec id="sec12">
                <title>3.3 Processes stages</title>
                <p>To develop didactic strategies to support learning in the Chemistry and General Chemistry I courses, four implementation phases were proposed, as illustrated in 
                    <xref ref-type="fig" rid="f2">
Figure 2</xref> and described in the subsequent subsections.
                    <list list-type="order">
                        <list-item>
                            <label>1)</label>
                            <p>Design of predictive trend analysis:
                                <list list-type="alpha-lower">
                                    <list-item>
                                        <label>a)</label>
                                        <p>Extraction of relevant data from exam performance in the Chemistry and General Chemistry I subjects, global and component Saber 11&#x00b0; exam scores, and the historical socio-demographic characterization of students.</p>
                                    </list-item>
                                    <list-item>
                                        <label>b)</label>
                                        <p>Construction of distribution tables of Saber 11&#x00b0; exam performance for the population during the academic periods from 2020-2 to 2023-1.</p>
                                    </list-item>
                                    <list-item>
                                        <label>c)</label>
                                        <p>Definition of trends within the performance indicators from the constructed distribution tables.</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>2)</label>
                            <p>Proposal of strategies to be implemented in academic spaces:
                                <list list-type="alpha-lower">
                                    <list-item>
                                        <label>a)</label>
                                        <p>Identification of relevant strategies (as identified by experts in the field) that have favored teaching-learning processes and achievement of academic success.</p>
                                    </list-item>
                                    <list-item>
                                        <label>b)</label>
                                        <p>Selection of teaching strategies, framed on experiential learning processes, that promote intrinsic and extrinsic motivation, recognized as having a potential positive impact on learning in the subjects Chemistry and General Chemistry I.</p>
                                    </list-item>
                                    <list-item>
                                        <label>c)</label>
                                        <p>Curricular alignment of selected strategies with assigned competencies and declared intended learning outcomes.</p>
                                    </list-item>
                                    <list-item>
                                        <label>d)</label>
                                        <p>Design of 3 strategies that respond to the learning needs of the participating students and that promote personalized learning processes, framed within didactic sequences for each strategy. The following questions are to be addressed:

                                            <list list-type="bullet">
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>What is the formative and disciplinary purpose of the expected learning outcomes, and how do these relate to the students&#x2019; comprehensive development and life plans?</p>
                                                </list-item>
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>What knowledge, skills, abilities, and attitudes have the greatest priority for the achievement of academic standards?</p>
                                                </list-item>
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>What active methodologies, didactic approaches, and cognitive processes are most appropriate to promote deep, meaningful, and transferable learning?</p>
                                                </list-item>
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>How will students, considering their diversity of styles, backgrounds, and contexts, engage in personalized and engaging learning experiences?</p>
                                                </list-item>
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>What teaching resources, materials, technologies, and environments will be used to mediate learning?</p>
                                                </list-item>
                                                <list-item>
                                                    <label>&#x2022;</label>
                                                    <p>What evidence, performance indicators, and formative assessment results allow verifying the level of achievement? (And how might these be improved?)</p>
                                                </list-item>
                                            </list>
                                        </p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                        <list-item>
                            <label>3)</label>
                            <p>Implementation of the strategies in academic spaces:

                                <list list-type="alpha-lower">
                                    <list-item>
                                        <label>a)</label>
                                        <p>Identification of students selected for being at risk of losing the performance indicators of the Chemistry and General Chemistry I subjects, using the constructed trends.</p>
                                    </list-item>
                                    <list-item>
                                        <label>b)</label>
                                        <p>Implementation of the strategies with the identified groups of students, with all information generated during the development of the face-to-face sessions collected through a data collection instrument focused on student perceptions.</p>
                                        <p>
The implementation was carried out over eight weeks during the 2023-2 and 2024-1 semesters, through weekly 1-hour face-to-face sessions led by the same course instructor.</p>
                                    </list-item>
                                    <list-item>
                                        <label>c)</label>
                                        <p>Evaluation of the impact of the implemented strategies on the academic success of the impacted students using formative evaluation processes.
</p>
                                    </list-item>
                                </list>
                            </p>
                        </list-item>
                    </list>
                </p>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>
Figure 2. </label>
                    <caption>
                        <title>Study phases for the development and implementation of teaching strategies.</title>
                    </caption>
                    <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure2.gif"/>
                </fig>
            </sec>
            <sec id="sec13">
                <title>3.4 Analysis categories</title>
                <p>The analysis categories were divided into two groups: input variables and output variables. The first group (input variables) included results obtained from the Saber 11&#x00b0; exam, considering both individual scores and scores by area of knowledge; data collected through instruments that assessed students&#x2019; cognitive styles; information from perception channels used to understand how students interacted with information; and results obtained in the Metacognitive Skills Inventory. These variables were essential for classifying students and characterizing their individual profiles, which served as the basis for designing and implementing personalized didactic strategies. The second group (output variables) included students&#x2019; perceptions of the implemented didactic strategies, which helped assess their effectiveness and students&#x2019; satisfaction with their applicability. Additionally, the level of competency achievement was considered, as reflected in student performance in midterm exams. These output variables were essential for measuring the impact of the didactic strategies on student learning and evaluating their performance based on the established learning outcomes. Together, these analysis categories provided a comprehensive view of the effectiveness of the didactic strategies and students&#x2019; academic performance.</p>
            </sec>
            <sec id="sec14">
                <title>3.5 Data analysis</title>
                <p>

                    <italic toggle="yes">3.5.1 Grading scale</italic>
                </p>
                <p>At Universidad de La Sabana, academic performance is assessed on a numerical grading scale ranging from 0.0 to 5.0, where 5.0 represents the highest possible achievement and 0.0 the lowest. The minimum passing grade established by institutional policy is 3.0. Scores below this threshold indicate unsatisfactory performance and are used as indicators of academic risk in the context of this study.</p>
                <p>

                    <italic toggle="yes">3.5.2 Statistical approach and justification</italic>
                </p>
                <p>Analysis of the collected quantitative data was conducted using IBM SPSS Statistics V25.0. The selection of statistical tests was guided by the research objectives and the characteristics of the collected data. The study aimed to identify relationships between students&#x2019; learning variables&#x2014;such as cognitive styles, perception channels, and metacognitive awareness&#x2014;and their academic performance, as well as to evaluate the impact of the implemented didactic strategies on students at risk of academic failure.</p>
                <p>Because the data were derived from ordinal scales and institutional performance scores that did not meet normality assumptions, non-parametric tests were applied. The Kolmogorov&#x2013;Smirnov test was first used to assess data distribution, and the results confirmed deviations from normality (p &lt; 0.05). Consequently, Spearman&#x2019;s Rho test was used to analyze correlations between variables, allowing the identification of associations among learning styles (VAK, CHAEA), metacognitive awareness (MAI), and academic performance in Chemistry and General Chemistry I.</p>
                <p>To compare academic performance between the control and experimental groups, the Mann&#x2013;Whitney U test was employed. This test was appropriate for determining whether differences existed between the groups in their distributions of academic performance and perceptions of the implemented strategies.</p>
                <p>In addition to determining statistical significance, the analysis also considered the practical significance of the observed differences. For this purpose, Cohen&#x2019;s d and Cohen&#x2019;s r were calculated to estimate the effect size of the implemented strategies on students&#x2019; academic performance. These measures allowed the interpretation of the magnitude and educational relevance of the impact produced by the didactic intervention, complementing the results obtained from hypothesis testing.</p>
                <p>This combination of statistical techniques provided a robust framework for addressing the study&#x2019;s objectives, enabling both the identification of meaningful relationships among variables and the evaluation of the effectiveness of the proposed didactic strategies in supporting the learning of students at risk of academic failure.</p>
            </sec>
            <sec id="sec15">
                <title>3.6 Instruments</title>
                <p>The instruments used were designed with the specific objectives of characterizing students and evaluating the designed strategies, especially with reference to students&#x2019; perceptions.</p>
                <p>All instruments were administered digitally via Google Forms. The VAK, CHAEA, and MAI questionnaires were applied before the intervention to characterize students&#x2019; learning styles, cognitive profiles, and metacognitive awareness. After the implementation of the didactic strategies, the adapted CEMPA perception survey was administered to evaluate students&#x2019; perceptions of the strategies and their effectiveness in supporting learning.</p>
                <p>

                    <italic toggle="yes">3.6.1 Perception channels</italic>
                </p>
                <p>To characterize perception channels, the VAK questionnaire originally designed by Felder and Silverman
                    <sup>
                        <xref ref-type="bibr" rid="ref70">70</xref>
                    </sup> was used; this questionnaire has been adapted multiple times.
                    <sup>
                        <xref ref-type="bibr" rid="ref71">71</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref73">73</xref>
                    </sup> The version adapted for the present study consisted of 10 items validated with a Cronbach&#x2019;s Alpha coefficient of 0.77.
                    <sup>
                        <xref ref-type="bibr" rid="ref74">74</xref>
                    </sup> The questionnaire was implemented in the study of Gamboa et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref75">75</xref>
                    </sup> to contextualize everyday situations, requiring respondents to recognize and select the sense through which they perceive them.</p>
                <p>

                    <italic toggle="yes">3.6.2 Cognitive styles</italic>
                </p>
                <p>The characterization of students&#x2019; cognitive styles was assessed using the CHAEA questionnaire designed by Honey and Mumford,
                    <sup>
                        <xref ref-type="bibr" rid="ref76">76</xref>
                    </sup> later modified by Alonso.
                    <sup>
                        <xref ref-type="bibr" rid="ref77">77</xref>
                    </sup> It consisted of 80 randomly distributed questions to address the four fundamental cognitive styles, each represented by 20 items. Respondents had to indicate whether they &#x201c;agreed&#x201d; or &#x201c;disagreed&#x201d; with the statements presented, based on their own perceptions and preferences.
                    <sup>
                        <xref ref-type="bibr" rid="ref78">78</xref>
                    </sup> The validity and reliability of the questionnaire were determined by Alonso et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref79">79</xref>
                    </sup> using Cronbach&#x2019;s Alpha, with values of 0.627 for the active style, 0.725 for the reflective style, 0.658 for the theoretical style, and 0.588 for the pragmatic style. This instrument was also implemented in the study of Gamboa et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref75">75</xref>
                    </sup>
                </p>
                <p>

                    <italic toggle="yes">3.6.3 Metacognitive awareness inventory</italic>
                </p>
                <p>The metacognitive skills of students who participated in the research were defined with the Metacognitive Awareness Inventory (MAI) developed by Schraw and Dennison in 1994. This is divided into two categories: cognition knowledge, with 17 items, and cognition regulation, with 35 items, each rated on a 5-point Likert scale.
                    <sup>
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref81">81</xref>
                    </sup> The cognition knowledge category includes subcategories such as declarative, procedural, and conditional knowledge, while the cognition regulation category encompasses elements such as planning, organization, monitoring, debugging, and evaluation, as detailed by Harrison and Vallin.
                    <sup>
                        <xref ref-type="bibr" rid="ref80">80</xref>
                    </sup> Planning involves organizing time, learning goals, and resources; organization refers to the systematization of learning activities; monitoring consists of overseeing the learning process during task execution; debugging is related to identifying weaknesses in learning to adjust strategies and improve performance; and evaluation focuses on analyzing the effectiveness of the strategies used in the learning process. Huertas et al.
                    <sup>
                        <xref ref-type="bibr" rid="ref82">82</xref>
                    </sup> validated this instrument in Colombia, explaining that declarative knowledge refers to an individual&#x2019;s understanding of their own learning process, abilities, and application; procedural knowledge relates to understanding of their how to use learning strategies; and conditional knowledge focuses on when and why to apply different learning strategies.</p>
                <p>

                    <italic toggle="yes">3.6.4 Perception survey on the effectiveness of didactic strategies</italic>
                </p>
                <p>After the implementation of each learning strategy, participating students completed a perception survey consisting of two sections. The first section was intended to assess the effectiveness of active participation methodologies (CEMPA) designed and validated by Carrasco et al.,
                    <sup>
                        <xref ref-type="bibr" rid="ref83">83</xref>
                    </sup> but included only 9 of the original 25 questions, as the excluded questions were not related to the aims of the present study. This initial survey section was validated for the student population at the Universidad de La Sabana, obtaining a Cronbach&#x2019;s Alpha of 0.959.
                    <sup>
                        <xref ref-type="bibr" rid="ref84">84</xref>
                    </sup> The second section of the survey explored students&#x2019; perceptions of the assurance of learning through each of the strategies, as well as their feedback and suggestions for improvement. All closed-ended questions were designed using a 5-point Likert scale.</p>
            </sec>
        </sec>
        <sec id="sec16" sec-type="results|discussion">
            <title>4. Results and discussion</title>
            <sec id="sec17">
                <title>4.1 Saber 11&#x00b0; results analysis</title>
                <p>Firstly, specific scores from the Saber 11&#x00b0; exam were considered, including the global score, critical reading, natural sciences, and mathematics. Frequency tables were constructed accordingly (
                    <xref ref-type="table" rid="T1">
Tables 1</xref>&#x2013;
                    <xref ref-type="table" rid="T4">4</xref>). These tables were then related to student performance in the topics that have historically had the highest failure rates in midterm assessments.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Frequency distribution of global Saber 11&#x00b0; exam scores.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">i</th>
                                <th align="left" colspan="2" rowspan="1" valign="top">Interval</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">m
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">f
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">r
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Measurement</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Stoichiometry</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>1</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">229</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">251</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">240</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.73%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.75
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.67
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>2</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">251</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">273</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">262</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">17</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.14%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.88
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.65
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>3</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">273</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">295</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">284</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">39</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">9.49%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.15
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.68
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>4</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">295</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">317</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">306</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">69</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">16.79%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.35
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.15
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>5</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">317</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">339</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">328</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">88</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">21.41%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.81
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.59
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>6</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">339</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">361</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">350</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">88</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">21.41%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.11</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.93
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>7</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">361</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">383</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">372</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">68</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">16.55%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.56</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.55</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>8</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">383</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">405</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">394</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6.08%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.07</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.88</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>9</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">405</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">427</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">416</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">9</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.19%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.18</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.44</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>10</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">427</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">449</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">438</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.22%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.10</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>m
                            <sub>i</sub> = class mark; </p>
                        <p>f
                            <sub>i</sub> = absolute frequency; </p>
                        <p>r
                            <sub>i</sub> = relative frequency.</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>Performance grades that indicate failure.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table 2. </label>
                    <caption>
                        <title>Frequency distribution of Saber 11&#x00b0; critical reading scores.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">i</th>
                                <th align="left" colspan="2" rowspan="1" valign="top">Interval</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">m
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">f
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">r
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Measurement</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Stoichiometry</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>1</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">46</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">43</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.22%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.03
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.25
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>2</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">46</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">49</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.43%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.40
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.45
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>3</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">58</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">55</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10.95%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.28
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.79
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>4</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">58</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">64</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">61</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">22.14%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.65
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.46
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>5</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">64</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">67</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">127</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">30.90%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.95
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.63
                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>6</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">76</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">73</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">100</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">24.33%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.24</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.28</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>7</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">76</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">82</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">79</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">26</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6.33%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.80</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>8</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">82</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">88</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">85</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.24%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5.00</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>9</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">88</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">94</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.24%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5.00</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>10</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">94</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">100</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">97</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.22%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.30</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>m
                            <sub>i</sub> = class mark; </p>
                        <p>f
                            <sub>i</sub> = absolute frequency; </p>
                        <p>r
                            <sub>i</sub> = relative frequency.</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn2">
                                <label>*</label>
                                <p>Performance grades that indicate failure.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Frequency distribution of Saber 11&#x00b0; natural sciences scores.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">i</th>
                                <th align="left" colspan="2" rowspan="1" valign="top">Interval</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">m
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">f
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">r
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Measurement</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Stoichiometry</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>1</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">39</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">42</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.97%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.90
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.00
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>2</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">48</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.87%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.03</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.03
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>3</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">57</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">54</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">31</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">7.54%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.15</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.07
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>4</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">57</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">63</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">77</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">18.73%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.43</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.42
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>5</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">63</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">69</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">66</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">116</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">28.22%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.63</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.93
                                    <xref ref-type="table-fn" rid="tfn3">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>6</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">69</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">75</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">72</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">101</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">24.57%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.82</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.21</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>7</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">75</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">81</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">78</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">53</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">12.90%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.33</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.92</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>8</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">81</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">84</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.49%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.75</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.63</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>9</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">93</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.00%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">N/A</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">N/A</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>10</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">93</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">100</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">97</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.70%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.95</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.00</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>m
                            <sub>i</sub> = class mark; </p>
                        <p>f
                            <sub>i</sub> = absolute frequency; </p>
                        <p>r
                            <sub>i</sub> = relative frequency.</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn3">
                                <label>*</label>
                                <p>Performance grades that indicate failure.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T4" orientation="portrait" position="float">
                    <label>
Table 4. </label>
                    <caption>
                        <title>Frequency distribution of Saber 11&#x00b0; mathematics scores.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">i</th>
                                <th align="left" colspan="2" rowspan="1" valign="top">Interval</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">m
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">f
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">r
                                    <sub>i</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Measurement</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Stoichiometry</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>1</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">35</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">42</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">38</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.49%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.80
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.00
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>2</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">42</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">49</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.49%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.55
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.69
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>3</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">49</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">56</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">23</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5.60%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.17</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.11
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>4</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">56</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">63</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">59</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">64</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">15.57%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.31</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.23
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>5</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">63</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">66</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">106</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25.79%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.59</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.66
                                    <xref ref-type="table-fn" rid="tfn4">*</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>6</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">77</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">73</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">142</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">34.55%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.72</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.21</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>7</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">77</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">84</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">12.41%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.21</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.78</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>8</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">84</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.49%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.50</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>9</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">91</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">94</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.73%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.50</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>10</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">105</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">102</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">16</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.89%</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.41</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.96</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>m
                            <sub>i</sub> = class mark; </p>
                        <p>f
                            <sub>i</sub> = absolute frequency; </p>
                        <p>r
                            <sub>i</sub> = relative frequency.</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn4">
                                <label>*</label>
                                <p>Performance grades that indicate failure.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <p>As evidenced by the data presented in 
                    <xref ref-type="table" rid="T1">
Tables 1</xref>&#x2013;
                    <xref ref-type="table" rid="T4">4</xref>, competencies in critical reading and mathematics play a fundamental role in academic performance within the measurement and stoichiometry modules. These skills not only influence understanding and application of the concepts addressed but also constitute an essential prerequisite for solving problems in which knowledge, skills, and attitudes are applied&#x2014;which in turn contributes to the achievement of a passing grade. In this regard, the development of such competencies at the high-school level is critical for supporting academic success at the university level and progression within the formative process of chemistry. This highlights the importance of strengthening these skills during earlier stages of education. However, given the evident lack of development in the pre-tertiary levels, it becomes necessary for HEIs to implement strategies that promote learning and foster the development of such competencies. This need aligns with national guidelines that emphasize the responsibility of HEIs for supporting students&#x2019; academic leveling and ensuring effective learning in disciplines such as chemistry.</p>
                <p>Moreover, a clear correlation is observed between the scores obtained and the level of academic performance. However, to statistically verify this relationship, the Kolmogorov-Smirnov normality test was conducted, with the results presented in 
                    <xref ref-type="table" rid="T5">
Table 5</xref>. These results show that the data distribution does not follow a normal distribution, indicating that the variables analyzed are non-parametric.</p>
                <table-wrap id="T5" orientation="portrait" position="float">
                    <label>
Table 5. </label>
                    <caption>
                        <title>
Kolmogorov-Smirnov normality test.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Global score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Critical reading score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Mathematics score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Social and citizenship score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Natural science score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Measurement</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Stoichiometry</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>
p-value
</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.178</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.001</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.004</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>Since this data does not follow a normal distribution, Spearman&#x2019;s rank-order correlation (Spearman&#x2019;s rho) test was used to evaluate the relationship between the variables analyzed. The results of this test, presented in 
                    <xref ref-type="table" rid="T6">
Table 6</xref>, indicate the degree of association among the studied variables.</p>
                <table-wrap id="T6" orientation="portrait" position="float">
                    <label>
Table 6. </label>
                    <caption>
                        <title>Spearmans correlations between Saber 11&#x00b0; exam scores and academic performance.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Global score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Critical reading score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Mathematics score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Social and citizenship score</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Natural science score</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">

                                    <bold>Measurement</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">

                                    <bold>p-value
</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Stoichiometry</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>p-value
</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.000</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>According to 
                    <xref ref-type="table" rid="T6">
Table 6</xref>, these results indicate statistically significant correlations between students&#x2019; academic performance and their Saber 11&#x00b0; scores across all evaluated areas. These results indicate that the correlations between students&#x2019; academic performance in the chemistry components (
                    <italic toggle="yes">Measurement</italic> and 
                    <italic toggle="yes">Stoichiometry</italic>) and their Saber 11&#x00b0; scores across all evaluated areas are statistically significant.</p>
                <p>This finding suggests that students&#x2019; achievement in chemistry is not isolated but is associated with broader cognitive and analytical competencies measured by the national standardized test. The significance of these correlations implies that the foundational skills assessed by Saber 11&#x00b0;, such as quantitative reasoning, reading comprehension, and scientific literacy, play a determining role in students&#x2019; ability to understand and apply chemical concepts.</p>
            </sec>
            <sec id="sec18">
                <title>4.2 Strategies design</title>
                <p>For the design of the strategies, a characterization process was carried out to develop resources appropriate to addressing students&#x2019; needs. Accordingly, correlations between learning styles, perceptual channels, and metacognitive skills were examined in relation to academic performance.</p>
                <p>As shown in 
                    <xref ref-type="table" rid="T7">
Table 7</xref>, no significant correlations were found between academic performance and students&#x2019; individual characteristics. This supports findings from neuroscientific and educational psychology research regarding perceptual channels and learning styles; namely, that it is a myth that individuals learn better when instruction is tailored to their preferred style or channel.
                    <sup>
                        <xref ref-type="bibr" rid="ref85">85</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>
                    </sup> Learning is a far more complex process that depends on multiple interacting factors.
                    <sup>
                        <xref ref-type="bibr" rid="ref17">17</xref>
                    </sup>
                </p>
                <table-wrap id="T7" orientation="portrait" position="float">
                    <label>
Table 7. </label>
                    <caption>
                        <title>Correlations between learner characteristics and academic performance.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="4" rowspan="1" valign="top">Learning styles</th>
                                <th align="left" colspan="3" rowspan="1" valign="top">Perceptual channels</th>
                            </tr>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Active</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Reflective</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Theoretical</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Pragmatic</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Visual</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Auditory</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Kinesthetic</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Measurement</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Cor. Cf.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.061</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.035</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.033</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.065</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.013</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.034</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.036</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.217</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.478</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.501</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.189</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.799</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.496</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.467</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Stoichiometry</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Cor. Cf.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.006</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.085</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.063</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.091</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.068</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.065</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.011</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.903</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.088</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.205</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.068</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.173</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.190</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.829</td>
                            </tr>
                        </tbody>
                    </table>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="2" rowspan="1" valign="top"/>
                                <th align="left" colspan="8" rowspan="1" valign="top">Metacognitive skills</th>
                            </tr>
                            <tr>
                                <th align="left" colspan="2" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Planning</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Organization</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Monitoring</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Debugging</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Evaluation</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Declarative</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Procedural</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Conditional</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Measurement</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Cor. Cf.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.042</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.086</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.064</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.023</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.002</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.074</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.036</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.399</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.082</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.194</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.647</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.969</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.136</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.691</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.466</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Stoichiometry</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Cor. Cf.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.034</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.030</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.015</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.015</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.028</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">-0.047</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.014</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.008</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.496</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.548</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.763</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.757</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.573</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.349</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.783</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.870</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>However, studies have demonstrated that learning is more effective when diverse approaches are integrated, rather than relying on a single dominant style.
                    <sup>
                        <xref ref-type="bibr" rid="ref85">85</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>
                    </sup> The teaching of measurement and stoichiometry involves analytical skills, mathematical reasoning, and conceptual understanding, none of which rely solely on a specific perceptual channel. For example, a student who identifies as a &#x201c;visual learner&#x201d; may not successfully master stoichiometric relationships merely by viewing chemical diagrams. Solving such problems requires mathematical practice, numerical analysis, and logical reasoning. Perceptual channels (visual, auditory, kinesthetic) are related to the way that information is initially received but do not determine cognitive processing capacity or academic performance.</p>
                <p>Consistent with this idea, the correlations shown in 
                    <xref ref-type="table" rid="T7">
Table 7</xref> revealed no statistically significant relationships between students&#x2019; performance in Measurement and Stoichiometry and their preferred learning styles or perceptual channels, as all p-values exceeded the 0.05 significance threshold. These results confirm that academic achievement in chemistry is not influenced by the sensory modality through which students prefer to receive information, but rather by their ability to apply logical reasoning, quantitative analysis, and conceptual understanding. In chemistry, concepts such as moles, chemical equations, and units of measurement demand logical and mathematical reasoning rather than sensory perception alone. Thus, regardless of a student&#x2019;s dominant learning style, effective learning in chemistry requires active engagement with problem-solving and abstraction.</p>
                <p>Metacognitive skills, such as planning, monitoring, and self-regulation, are important for overall academic success.
                    <sup>
                        <xref ref-type="bibr" rid="ref88">88</xref>
                    </sup>
                    <sup>,</sup>
                    <sup>
                        <xref ref-type="bibr" rid="ref89">89</xref>
                    </sup> However, while metacognition can help students recognize errors in their thinking, it cannot compensate for a lack of mastery in foundational principles. Being aware of one&#x2019;s learning is insufficient on its own; students must also actively engage in problem-solving to improve performance. In this sense, academic success in chemistry depends on students&#x2019; comprehension of fundamental physical quantities, unit conversions, and stoichiometric relationships. The process of problem-solving strengthens reasoning and facilitates knowledge application. Therefore, identifying effective learning strategies and techniques that promote the development of logical-mathematical thinking is essential.</p>
            </sec>
            <sec id="sec19">
                <title>4.3 Strategy design</title>
                <p>

                    <italic toggle="yes">4.3.1 Leveling/reinforcement course</italic>
                </p>
                <p>First, a leveling (or reinforcement) course was implemented, based on the guidelines established in Decree 869 of 2010, which emphasize that the classification of students supports their prioritized participation in academic leveling programs and the implementation of dropout prevention measures. This course was divided into seven sections: diagnosis, measurement, dimensional analysis, practical case study, general notions of chemistry, final case study, and course closure. The course resources included explanatory videos, theoretical presentations, interactive and practical exercises, formative assessments, and case studies. The course&#x2019;s curricular alignment is illustrated in 
                    <xref ref-type="fig" rid="f3">
Figure 3</xref>; the course&#x2019;s online interfaces are shown in 
                    <xref ref-type="fig" rid="f4">
Figure 4</xref>.</p>
                <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                    <label>
Figure 3. </label>
                    <caption>
                        <title>Curricular alignment of the leveling course.</title>
                    </caption>
                    <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure3.gif"/>
                </fig>
                <fig fig-type="figure" id="f4" orientation="portrait" position="float">
                    <label>
Figure 4. </label>
                    <caption>
                        <title>Representative screen of the leveling course.</title>
                    </caption>
                    <graphic id="gr4" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure4.gif"/>
                </fig>
                <p>In implementing the leveling course, students were first classified according to the identified models, focusing on those with global Saber 11&#x00b0; scores below 339 and language scores below 70. The resources and work schedule were then shared with them digitally, and their participation was monitored continuously. As part of this monitoring process, student engagement in evaluations and activities was reviewed. Structured case studies were conducted to develop critical reading skills aimed at problem identification, formulation, and resolution. The development of critical and analytical thinking in chemistry is essential to train professionals capable of analyzing problems, evaluating scientific information, and making informed decisions. Critical thinking in chemistry involves the ability to interpret data, formulate hypotheses, design procedures, and rigorously analyze results; it is a disciplinary and intellectual process that helps students make logical and reflective judgments about how to proceed in problem-solving contexts, and chemistry students can significantly enhance these skills through project-based learning and the integration of metacognitive strategies.
                    <sup>
                        <xref ref-type="bibr" rid="ref90">90</xref>
                    </sup>
                </p>
                <p>

                    <italic toggle="yes">4.3.2 Gamified kit</italic>
                </p>
                <p>The second strategy designed was titled the &#x201c;Conversion Conquerors Kit,&#x201d; created to help students master the use of conversion factors and their application in chemistry. Through a gamified approach, three sets of activities were presented, including educational materials such as cards, boards, and practical exercises. The objective was for students to develop unit conversion skills through exploration, dimensional analysis, and problem-solving in context. The material was divided into three modules:
                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>Symbol conversion: introduction to symbols and basic units through 25 cards, in which students explored these elements as a foundation for developing conversions.</p>
                        </list-item>
                        <list-item>
                            <label>2.</label>
                            <p>Unit matching: use of a didactic board with markers to identify unit equivalences and create pairs, strengthening the understanding of relationships between magnitudes.</p>
                        </list-item>
                        <list-item>
                            <label>3.</label>
                            <p>&#x201c;Conquering&#x201d; factors: use of cards to carry out conversions through dimensional analysis.</p>
                        </list-item>
                    </list>
                </p>
                <p>Students had to apply the conversion factors to practical problems and exercises. Each module included interactive cards, practical exercises, and a guide to facilitate progressive development of conversion skills. QR codes were also used to access additional missions and challenges. The implementation methodology included the following phases:
                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>Exploration: students were presented with cards showing symbols and units they had to recognize.</p>
                        </list-item>
                        <list-item>
                            <label>2.</label>
                            <p>Matching game: activities for matching equivalent units.</p>
                        </list-item>
                        <list-item>
                            <label>3.</label>
                            <p>Dimensional analysis: exercises requiring correct application of conversion factors.</p>
                        </list-item>
                        <list-item>
                            <label>4.</label>
                            <p>Contextual application: solving chemistry problems that involve the conversions learned.</p>
                        </list-item>
                    </list>
                </p>
                <p>The kit&#x2019;s curricular alignment is shown in 
                    <xref ref-type="fig" rid="f5">
Figure 5</xref>, and examples of the kit&#x2019;s virtual card designs are shown in 
                    <xref ref-type="fig" rid="f6">
Figure 6</xref>.</p>
                <fig fig-type="figure" id="f5" orientation="portrait" position="float">
                    <label>
Figure 5. </label>
                    <caption>
                        <title>Curricular alignment of the &#x201c;Conversion Conquerors Kit&#x201d;.</title>
                    </caption>
                    <graphic id="gr5" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure5.gif"/>
                </fig>
                <fig fig-type="figure" id="f6" orientation="portrait" position="float">
                    <label>
Figure 6. </label>
                    <caption>
                        <title>Example cards from the &#x201c;Conversion Conquerors Kit&#x201d;.</title>
                    </caption>
                    <graphic id="gr6" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure6.gif"/>
                </fig>
                <p>The development of the &#x201c;Conversion Conquerors Kit&#x201d; strategy was grounded in various pedagogical and theoretical approaches related to learning scientific and mathematical concepts, dimensional analysis, and unit conversion in the context of chemistry, with an emphasis on meaningful learning and knowledge construction.</p>
                <p>According to Ausubel,
                    <sup>
                        <xref ref-type="bibr" rid="ref91">91</xref>
                    </sup> meaningful learning occurs most effectively when new information is linked to existing cognitive structures. In unit conversion, students must integrate conversion factors with their prior knowledge of physical and mathematical magnitudes. Novak
                    <sup>
                        <xref ref-type="bibr" rid="ref92">92</xref>
                    </sup> argues that meaningful learning, in contrast with rote memorization, promotes long-term retention. In chemistry, understanding units and their relationships supports the correct application of conversion factors in complex problems, which is why the &#x201c;Conversion Conquerors Kit&#x201d; strategy began with basic symbol identification before advancing to higher-order skills.</p>
                <p>From a constructivist perspective, knowledge is actively built through interaction with the environment.
                    <sup>
                        <xref ref-type="bibr" rid="ref93">93</xref>
                    </sup> Vygotsky
                    <sup>
                        <xref ref-type="bibr" rid="ref94">94</xref>
                    </sup> emphasized the importance of social mediation in learning processes. In the &#x201c;Conversion Conquerors Kit&#x201d;, students interacted with cards and learning tools to explore conversion concepts, promoting experiential learning. The use of gamified materials strengthens the conceptualization of unit equivalence and dimensional analysis, in alignment with Bruner&#x2019;s
                    <sup>
                        <xref ref-type="bibr" rid="ref95">95</xref>
                    </sup> view that learning is enhanced when students interact tangibly with concepts. Game-based learning has been shown to be effective in increasing student motivation and engagement in scientific disciplines.
                    <sup>
                        <xref ref-type="bibr" rid="ref96">96</xref>
                    </sup> Gamification in chemistry education has been employed to develop analytical skills and promote active learning.
                    <sup>
                        <xref ref-type="bibr" rid="ref97">97</xref>
                    </sup> Moreover, the use of cards, boards, and interactive challenges in the kit fosters autonomous learning and skill development in unit conversion. According to Vera-Monroy et al.,
                    <sup>
                        <xref ref-type="bibr" rid="ref98">98</xref>
                    </sup> integrating games into educational processes enhances conceptual understanding and helps students apply knowledge in varied contexts.</p>
                <p>Finally, instruction should be connected to real-world problem-solving situations to ensure learning transfer.
                    <sup>
                        <xref ref-type="bibr" rid="ref99">99</xref>
                    </sup> Chi and Vanlehn
                    <sup>
                        <xref ref-type="bibr" rid="ref100">100</xref>
                    </sup> argue that contextualized learning improves students&#x2019; abilities to apply knowledge across disciplines. In chemistry and engineering, unit conversion is a fundamental skill, enabling accurate interpretation of experimental data and equation solving. Therefore, the &#x201c;Conversion Conquerors Kit&#x201d; strategy incorporated applied problems to promote knowledge transfer to practical scenarios.</p>
                <p>Given that the interventions were designed to support students at risk of academic failure, 
                    <xref ref-type="table" rid="T8">
Table 8</xref> summarizes the didactic strategies implemented, their targeted learning needs, and the essential steps for implementation. To facilitate replication across institutions, the table reports transferable components while excluding platform-specific interfaces and other proprietary details.</p>
                <table-wrap id="T8" orientation="portrait" position="float">
                    <label>
Table 8. </label>
                    <caption>
                        <p>Summary of the didactic strategies.</p>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Strategy</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Targeted learning need</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Components</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Learning resources</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Leveling/reinforcement course</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Strengthen foundational content needed for success in Chemistry and General Chemistry I</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Seven sections: diagnosis; measurement; dimensional analysis; practical case study; general notions of chemistry; final case study; closure</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Explanatory videos, theoretical presentations, interactive/practical exercises, formative assessments, and case studies</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Gamified unit-conversion kit (game-based learning)</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Develop mastery of conversion factors and unit conversion through dimensional analysis and contextual problem-solving</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Three modules: (1) symbol conversion (symbols/basic units via a deck of cards); (2) unit matching (board-based pairing of equivalent units); (3) applying conversion factors through dimensional analysis; followed by contextual application problems</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Cards, a matching board, practical exercises, a short guide for progressive development; optional QR-linked challenges/missions</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec id="sec20">
                <title>4.4 Assessment of the strategies</title>
                <p>To assess the effectiveness of the two strategies used in the present study&#x2014;the leveling course and the gamified kit&#x2014;students&#x2019; performance on competency-based tests and their perceptions were analyzed. Initially, results were gathered from students who participated in only the first strategy, only the second strategy, and those who engaged in both, regardless of their classification in the Saber 11&#x00b0; exam. The results are presented in 
                    <xref ref-type="table" rid="T9">
Table 9</xref>.</p>
                <table-wrap id="T9" orientation="portrait" position="float">
                    <label>
Table 9. </label>
                    <caption>
                        <title>Average grade according to student participation.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Leveling course</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Gamified kit</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Both</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Participated</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.53</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.47</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.54</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Did not participate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.07</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.14</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.09</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>As shown in 
                    <xref ref-type="table" rid="T9">
Table 9</xref>, in all cases, the participants&#x2019; performance was higher than that of non-participants. This suggests that participation in the strategies had a positive effect on academic outcomes. However, to determine whether these differences were statistically significant, the Mann-Whitney U test was applied, as shown in 
                    <xref ref-type="table" rid="T10">
Table 10</xref>.</p>
                <table-wrap id="T10" orientation="portrait" position="float">
                    <label>
Table 10. </label>
                    <caption>
                        <title>Mann-Whitney U test p-values.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Leveling course</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Gamified kit</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Both</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.096</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.246</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.090</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>As shown in 
                    <xref ref-type="table" rid="T10">
Table 10</xref>, none of the p-values reached the conventional level of statistical significance (p &lt; 0.05). Specifically, the 
                    <italic toggle="yes">Leveling course</italic> (p = 0.096), 
                    <italic toggle="yes">Gamified kit</italic> (p = 0.246), and 
                    <italic toggle="yes">Combined strategies</italic> (p = 0.090) all produced non-significant results. Although the mean performance of participating students tended to be higher than that of non-participants, these differences should be interpreted cautiously, as they do not provide sufficient statistical evidence to confirm a measurable effect.</p>
                <p>These results are consistent with the scope of this initial analysis, which included data from all participating students without prioritization or segmentation by risk level or prior performance. When the entire population is considered as a single group, variability in background knowledge and motivation may dilute the observable impact of the interventions, reducing the likelihood of detecting statistically significant effects.</p>
                <p>Nevertheless, the lower p-values observed for the 
                    <italic toggle="yes">Leveling course</italic> and the 
                    <italic toggle="yes">Combined strategies</italic> suggest a potential trend toward improvement that may indicate practical relevance, even if it does not meet the conventional threshold for significance. This trend could reflect an underlying interaction between the two interventions, warranting further analysis with a larger or more homogeneous sample to verify whether the apparent synergy observed in this study represents a consistent effect on academic performance.</p>
                <p>Next, the effect of prioritizing strategies was analyzed by examining the performance of students with global scores below 339 and specific scores below 70 in both critical reading and mathematics. Results for participants and non-participants are shown in 
                    <xref ref-type="table" rid="T11">
Table 11</xref>.</p>
                <table-wrap id="T11" orientation="portrait" position="float">
                    <label>
Table 11. </label>
                    <caption>
                        <title>Average grade according to student participation by Saber 11&#x00b0; classification.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Leveling course</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Gamified kit</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Both</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Participated</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.31</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.24</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.29</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Did not participate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.48</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.58</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d Cohen</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.01</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.75</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.39</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>r Cohen</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.45</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.35</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.57</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>As shown in 
                    <xref ref-type="table" rid="T11">
Table 11</xref>, participants in either or both strategies exceeded the minimum passing grade of 3.0, achieving mean scores of 3.31 for the Leveling course, 3.24 for the Gamified Kit, and 3.29 for the combined implementation. Conversely, students who did not participate in any strategy failed to meet the passing grade in all cases, with average scores between 2.48 and 2.60. This pattern indicates that participation in the proposed didactic interventions was associated with higher academic achievement in Chemistry and General Chemistry I, even though grades should not be viewed as the ultimate goal of learning but rather as indicators of progress toward achieving learning outcomes and developing competencies. From this perspective, the presence of structured educational strategies plays a fundamental role in fostering meaningful learning processes and reducing the risk of academic failure.
                    <sup>
                        <xref ref-type="bibr" rid="ref101">101</xref>
                    </sup>
                </p>
                <p>Beyond mean differences, the analysis of effect sizes provides further insight into the practical impact of the strategies. The Leveling course presented a Cohen&#x2019;s d of 1.01 (r = 0.45), corresponding to a large effect size, which indicates a strong practical influence on students&#x2019; performance. The Gamified kit showed a d of 0.75 (r = 0.35), representing a moderate effect, while the combined implementation of both strategies yielded the highest effect size (d = 1.39, r = 0.57), suggesting a substantial cumulative benefit when the strategies were integrated. These results imply that, although the p-values from 
                    <xref ref-type="table" rid="T9">
Table 9</xref> did not reach conventional statistical significance, the magnitude of improvement observed among participants is educationally relevant and consistent with meaningful changes in performance.</p>
                <p>In this sense, the leveling course appears particularly effective in supporting students&#x2019; conceptual understanding, likely due to its structured review of foundational content and personalized academic support. Meanwhile, the gamified kit may have enhanced motivation and engagement, facilitating the reinforcement of theoretical knowledge through active learning. When both were implemented together, their complementary mechanisms appeared to generate a synergistic effect, reflected in the highest observed mean and effect size. These findings highlight the importance of combining pedagogical interventions that address both cognitive and affective dimensions of learning to promote sustained academic improvement.</p>
                <p>The statistical significance of these differences was analyzed, and the results are shown in 
                    <xref ref-type="table" rid="T12">
Table 12</xref>.</p>
                <table-wrap id="T12" orientation="portrait" position="float">
                    <label>
Table 12. </label>
                    <caption>
                        <title>Mann-Whitney U test for prioritized students.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Leveling course</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Gamified kit</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Both</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">p-value
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.007</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.035</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.027</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>The leveling course strategy yielded the lowest p-value (0.007), indicating that the performance difference between participants and non-participants was highly significant. This supports the conclusion that this strategy had a real impact on improving learning outcomes. The low probability that the observed difference occurred by chance reinforces the importance of implementing this strategy, as it offers the possibility of substantial performance improvements. Nevertheless, although it is essential to emphasize that grades are merely a consequence of an educational process, the average grade of 3.31 among participants in the leveling course (
                    <xref ref-type="table" rid="T11">
Table 11</xref>) emphasizes that its value lies not only in helping students meet passing criteria but in fostering learning needed for long-term academic success. This, moreover, aligns with the principles outlined in Decree 869 of 2010, which emphasize the need for leveling courses to promote academic success.</p>
                <p>As shown in 
                    <xref ref-type="table" rid="T12">
Table 12</xref>, the gamified kit strategy also resulted in a statistically significant difference (p = 0.035), confirming its effectiveness in enhancing academic performance. Although the average score improvement of 3.24 was smaller than that associated with the reinforcement course (3.31), this outcome still reflects the development of relevant skills and competencies amongst the participants. Statistical significance further validates the gamified kit strategy as a valuable tool to support academic success.</p>
                <p>The p-value for the gamified kit strategy (0.035) also indicates a statistically significant difference between those who participated and those who did not, confirming the positive impact of the intervention. Although the score difference and significance level are lower than those observed for the reinforcement course, the results still demonstrate that the gamified kit supports student achievement. Students using only the gamified kit strategy achieved an average grade of 3.24, surpassing the minimum passing grade (3.0), evidencing the development of key academic skills and knowledge appropriation.</p>
                <p>As also shown in 
                    <xref ref-type="table" rid="T12">
Table 12</xref>, the p-value for the combination of both strategies (0.027) indicates that their combined impact is statistically significant, although not as strong as that of the reinforcement course alone. However, the average grade of participants in the reinforcement course alone (3.31) is not substantially greater than that of participants in both strategies (3.29). This suggests that, while combining both strategies may be useful, it does not generate a stronger synergistic effect than that of the leveling course alone.</p>
                <p>Finally, students&#x2019; perceptions of the implemented strategies were assessed, as presented in 
                    <xref ref-type="fig" rid="f7">
Figure 7</xref>. The results obtained from show a highly positive perception of the implemented teaching strategies. All statements evaluated obtained averages above 4.3 (on a scale of 1 to 5), indicating high overall satisfaction.</p>
                <fig fig-type="figure" id="f7" orientation="portrait" position="float">
                    <label>
Figure 7. </label>
                    <caption>
                        <title>Student perceptions of the strategies.</title>
                    </caption>
                    <graphic id="gr7" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/195364/229d6460-47cf-4d77-a4ed-8bd517443f89_figure7.gif"/>
                </fig>
                <p>The highest-rated item was &#x201c;teaches how to follow instructions&#x201d;, with a perfect score of 5.00, reflecting the notion that the strategies effectively support the development of procedural skills and the ability to follow directions, which are essential aspects for educational contexts aimed at strengthening guided student autonomy. This was followed by items rated at 4.92: &#x201c;allows demonstration of what has been learned&#x201d;, &#x201c;is to my liking/I like it&#x201d;, and &#x201c;encourages participatory attitudes&#x201d;. These scores suggest that students not only find the strategies useful for expressing their learning but also perceive them as engaging and conducive to active participation.</p>
                <p>Other highly rated items (&#x2265;4.7) include &#x201c;innovative way to promote problem-solving skills&#x201d; (4.83), &#x201c;facilitates learning of the topic&#x201d; (4.83), and &#x201c;engages students in their own learning&#x201d; (4.80). These results indicate that the strategies significantly contributed to the development of higher-order competencies, such as problem-solving, deep understanding of content, and active engagement in the learning process.</p>
                <p>The item &#x201c;similar strategies should be designed for other subjects&#x201d; received a mean score of 4.75, reflecting students&#x2019; recognition of the strategies&#x2019; values beyond their immediate context and their potential for transferability and scalability across other curricular areas.</p>
                <p>Although the item &#x201c;is essential for the course&#x201d; received the lowest score (4.33), this still falls within a positive range. It suggests that, while the strategy is perceived as valuable, it may be seen more as complementary rather than as a central component of the courses. This perception highlights an opportunity for improved curricular integration of active learning strategies within instructional design.</p>
                <p>Student acceptance and positive evaluation are critical for the success of any educational strategy. When students perceive extracurricular activities as relevant and beneficial, they are more likely to engage actively, thereby amplifying the associated learning benefits. Furthermore, favorable perceptions can increase motivation and commitment, which are both essential elements for effective learning.
                    <sup>
                        <xref ref-type="bibr" rid="ref102">102</xref>
                    </sup> In this way, extracurricular strategies play a fundamental role in higher education by complementing traditional academic instruction and contributing to students&#x2019; holistic development. They are essential in higher education as they enhance and promote the development of key skills for professional success.</p>
                <p>Positive student perceptions are crucial to the effectiveness of these activities, as perception directly influences participation and engagement. Academic literature supports these findings, emphasizing the need to integrate and value extracurricular activities in the university setting. The present study&#x2019;s findings corroborate those of D&#x00ed;az-Iso and Garc&#x00ed;a-Olalla,
                    <sup>
                        <xref ref-type="bibr" rid="ref103">103</xref>
                    </sup> who likewise argue that participation in extracurricular activities can have a positive impact on university students&#x2019; comprehensive development, enhancing both their academic performance and personal growth.</p>
                <p>In addition to the students&#x2019; evaluations, teachers were also invited to share their perceptions regarding the implemented teaching strategies. Their responses provide valuable insights into the pedagogical impact and practicality of these tools within the classroom context.</p>
                <p>Overall, teachers expressed a highly favorable perception, emphasizing the strategies&#x2019; potential to improve engagement, conceptual understanding, and the development of autonomous learning. As one instructor noted:
                    <disp-quote>
                        <p>&#x201c;The activities encouraged students to take ownership of their learning and to connect theoretical concepts with real applications.&#x201d; &#x2014; (Professor A, Chemistry subject)</p>
                    </disp-quote>
                </p>
                <p>Another teacher highlighted the observable change in student participation and motivation, stating:

                    <disp-quote>
                        <p>&#x201c;These approaches truly embody active learning. They transform the role of the teacher into a facilitator and that of the student into a protagonist of their own learning&#x2014;precisely the purpose envisioned for the co-curricular strategies.&#x201d; &#x2014; (Professor B, General Chemistry I subject)</p>
                    </disp-quote>
                </p>
                <p>These insights reflect a shared recognition of the value of the implemented strategies for promoting engagement, critical thinking, and meaningful learning experiences. Teachers perceive them as powerful instruments for bridging theory and practice, while also identifying the importance of professional development to sustain long-term pedagogical innovation.</p>
            </sec>
        </sec>
        <sec id="sec21" sec-type="conclusions">
            <title>5. Conclusions</title>
            <p>The design and implementation of personalized and contextualized didactic strategies for students at risk of academic failure proved to be effective in improving academic performance in the courses of Chemistry and General Chemistry I. The leveling course strategy showed the most substantial positive impact, with statistically significant differences in academic outcomes between participants and non-participants, especially among students with low Saber 11&#x00b0; exam scores.</p>
            <p>The gamified kit strategy (&#x201c;Conversion Conquerors Kit&#x201d;) also had a positive effects; however, its impact appeared to be more multidimensional than purely academic. Beyond contributing to performance improvement, the kits design fostered greater engagement, motivation, and curiosity, generating an environment that encouraged active participation and collaborative learning. When integrated with structured reinforcement strategies, it appeared to enhance not only learning outcomes but also the development of scientific reasoning, procedural thinking and problem-solving skills. This demonstrates the value of incorporating innovative and playful strategies in higher education to support competency-based learning and long-term academic success.</p>
            <p>Students&#x2019; perceptions of the implemented strategies were highly positive, indicating strong levels of satisfaction regarding their usefulness, engagement, and applicability. This collective feedback underscores the pedagogical potential of the strategies according to their scalability and relevance for other academic subjects, while also suggesting that their effectiveness may vary depending on contextual and disciplinary factors.</p>
            <p>No significant correlations were found between academic performance and students&#x2019; learning styles, perceptual channels, or metacognitive skills, reinforcing the notion that learning is a complex process that requires diverse competency-based strategies rather than reliance solely on individual preferences.</p>
            <p>Overall, these findings highlight the importance of strengthening AoL processes in basic science courses, showing that early, targeted interventions can help reduce course repetition and dropout rates in higher education.</p>
            <p>Finally, the results of this study emphasize the value of active learning, critical thinking, and student motivation as key components in the development of effective teaching strategies to ensure educational quality and student success in engineering programs.</p>
        </sec>
        <sec id="sec22">
            <title>Ethics and consent</title>
            <sec id="sec23">
                <title>Ethics approval and consent to participate</title>
                <p>The study was approved by the Research Ethics Committee (REC) of the Universidad de La Sabana during its regular session No. 136 on November 24, 2024. Likewise, the General Directorate of Research authorized the start of the project under code ING-303-2022.</p>
                <p>All participants included in the research signed the written informed consent approved by the ethics committee, attached to the extended data.</p>
            </sec>
        </sec>
        <sec id="sec24">
            <title>Authors contributions</title>
            <p>

                <bold>Monsalve-Silva S:</bold> Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing &#x2013; Original Draft Preparation, Writing &#x2013; Review and Editing; 
                <bold>Berm&#x00fa;dez-Aponte, JJ:</bold> Funding Acquisition, Project Managment, Resources, Validation, Writing &#x2013; Review and Editing; 
                <bold>Vera-Monroy SP:</bold> Conceptualization, Formal Analysis, Research, Methodology, Supervision, Validation, Writing &#x2013; Original Draft Preparation.</p>
        </sec>
    </body>
    <back>
        <sec id="sec25" sec-type="data-availability">
            <title>Data availability</title>
            <sec id="sec26">
                <title>Extended data</title>
                <p>Extended data - Implementation of didactic strategies for assurance of learning with students at risk of academic failure in general chemistry. Zenodo. 2025. doi: 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.15540413">https://doi.org/10.5281/zenodo.15540413</ext-link>.
                    <sup>
                        <xref ref-type="bibr" rid="ref104">104</xref>
                    </sup>
                </p>
                <p>The project contains the following extended data:
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Questionnaires</p>
                        </list-item>
                        <list-item>
                            <label>&#x2022;</label>
                            <p>Example consent forms</p>
                        </list-item>
                    </list>
                </p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
            </sec>
            <sec id="sec27">
                <title>Underlying data</title>
                <p>&#x201c;Dataset - Implementation of didactic strategies for assurance of learning with students at risk of academic failure in general chemistry&#x201d;. Zenodo, June 25, 2025. doi: 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.15677974">https://doi.org/10.5281/zenodo.15677974</ext-link>.
                    <sup>
                        <xref ref-type="bibr" rid="ref105">105</xref>
                    </sup>
                </p>
                <p>Dataset associated with this article supporting the results and analyses.</p>
                <p>Data are available under the terms of the 
                    <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
            </sec>
        </sec>
        <ack>
            <title>Acknowledgments</title>
            <p>We thank the Universidad de La Sabana and the Direcci&#x00f3;n General de Investigaci&#x00f3;n for the support received in the development of this project.</p>
        </ack>
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    </back>
    <sub-article article-type="reviewer-report" id="report453312">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.195364.r453312</article-id>
            <title-group>
                <article-title>Reviewer response for version 3</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Asli</surname>
                        <given-names>Sare</given-names>
                    </name>
                    <xref ref-type="aff" rid="r453312a1">1</xref>
                    <xref ref-type="aff" rid="r453312a2">2</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3754-4613</uri>
                </contrib>
                <aff id="r453312a1">
                    <label>1</label>Science &amp; Technology, Al-Qasemi Academic College, Baqa El-Garbiah, Israel</aff>
                <aff id="r453312a2">
                    <label>2</label>Science Education, The Institute of Applied Research, Galilee Society, Shefa-'Amr, Israel</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>30</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Asli S</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport453312" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.3"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>I think the authors have made a clear effort to address the main points raised in the previous review. In my opinion, the introduction is now more coherent, a summary of the strategies has been included, and the figures and tables are more consistent and better presented. Overall, I think the manuscript has improved considerably. There are still some minor issues related to conciseness and the depth of explanation, but in my view, these do not affect the overall quality of the work and could be further refined.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Environmental Engineering, Agrobiology, Science Education for Sustainability, and Educational Methods in STEM</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report463372">
        <front-stub>
            <article-id pub-id-type="doi"/>
            <title-group>
                <article-title>Reviewer response for version 3</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Abril</surname>
                        <given-names>Diana</given-names>
                    </name>
                    <xref ref-type="aff" rid="r463372a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <contrib contrib-type="author">
                    <name>
                        <surname>Mi&#x00f1;o</surname>
                        <given-names>Luis</given-names>
                    </name>
                    <xref ref-type="aff" rid="r463372a2">2</xref>
                    <role>Co-referee</role>
                </contrib>
                <aff id="r463372a1">
                    <label>1</label>Universidad Cat&#x00f3;lica del Maule, Talca, Chile</aff>
                <aff id="r463372a2">
                    <label>2</label>Biolog&#x00ed;a y Qu&#x00ed;mica, Universidad Catolica del Maule, Talca, Maule Region, Chile</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>30</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Abril D and Mi&#x00f1;o L</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport463372" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.3"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>1. Overall evaluation of the manuscript</p>
            <p> The manuscript addresses a relevant problem in higher education: low academic performance and dropout rates in introductory chemistry courses within engineering programs. The study proposes and implements didactic strategies aimed at students identified as being at risk of academic failure through the analysis of results from the Saber 11 examination.</p>
            <p> The study presents a mixed-methods methodological design with a quasi-experimental approach and incorporates statistical analyses appropriate for non-parametric data. Additionally, it proposes concrete pedagogical strategies&#x2014;a leveling course and a gamified unit-conversion kit&#x2014;aimed at strengthening fundamental competencies in chemistry.</p>
            <p> The manuscript represents a potentially valuable contribution to the literature on pedagogical interventions in basic sciences, particularly in Latin American higher education contexts. Nevertheless, the article requires some improvements in conceptual clarity, methodological justification, and discussion of results before it can be considered fully acceptable for indexing</p>
            <p> 2. Strengths of the manuscript 
                <list list-type="order">
                    <list-item>
                        <p>Relevance of the research problem. The study addresses a problem widely documented in the international literature: high rates of academic failure in introductory basic science courses, particularly in chemistry.</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>Clear institutional contextualization. The manuscript presents concrete data on pass, failure, and dropout rates in the analyzed courses, allowing readers to clearly understand the magnitude of the problem within the institutional context.</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>Coherent methodological design. The use of a mixed-methods approach and non-parametric statistical tests (Kolmogorov&#x2013;Smirnov, Spearman, and Mann&#x2013;Whitney) is appropriate for the type of data analyzed.</p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>Applicable pedagogical proposal. The didactic strategies designed have potential for replication in other higher education institutions.</p>
                    </list-item>
                </list> 3. Major comments</p>
            <p> 3.1 Clarification of the conceptual framework</p>
            <p> The manuscript presents an extensive literature review; however, its conceptual organization could be improved. Currently, several topics are addressed simultaneously, including: 
                <list list-type="bullet">
                    <list-item>
                        <p>assurance of learning</p>
                    </list-item>
                    <list-item>
                        <p>academic performance</p>
                    </list-item>
                    <list-item>
                        <p>university dropout</p>
                    </list-item>
                    <list-item>
                        <p>science education</p>
                    </list-item>
                    <list-item>
                        <p>pedagogical strategies</p>
                    </list-item>
                </list> However, the conceptual relationships among these elements are not presented with sufficient clarity.</p>
            <p> It is recommended to reorganize the theoretical framework around three main conceptual axes: 
                <list list-type="order">
                    <list-item>
                        <p>Difficulties in learning chemistry in higher education</p>
                    </list-item>
                    <list-item>
                        <p>Early identification of academic risk</p>
                    </list-item>
                    <list-item>
                        <p>Pedagogical interventions to improve learning in basic sciences</p>
                    </list-item>
                </list> In addition, it would be advisable to include a conceptual model or figure representing the relationships among: 
                <list list-type="bullet">
                    <list-item>
                        <p>input variables (Saber 11 results, student characteristics),</p>
                    </list-item>
                    <list-item>
                        <p>the didactic intervention,</p>
                    </list-item>
                    <list-item>
                        <p>learning outcomes.</p>
                    </list-item>
                </list> 3.2 Methodological justification of the quasi-experimental design</p>
            <p> The study is described as quasi-experimental; however, the explanation of the research design could be strengthened. In particular, the manuscript does not sufficiently explain: 
                <list list-type="bullet">
                    <list-item>
                        <p>how potential self-selection bias was controlled,</p>
                    </list-item>
                    <list-item>
                        <p>why random assignment was not applied,</p>
                    </list-item>
                    <list-item>
                        <p>what measures were taken to reduce potential confounding variables.</p>
                    </list-item>
                </list> It is suggested to incorporate an additional subsection explaining: 
                <list list-type="bullet">
                    <list-item>
                        <p>the rationale for the quasi-experimental design,</p>
                    </list-item>
                    <list-item>
                        <p>the limitations associated with voluntary participation,</p>
                    </list-item>
                    <list-item>
                        <p>the implications for interpreting the results.</p>
                    </list-item>
                </list> 3.3 Discussion of statistical results</p>
            <p> The results indicate that students who participated in the strategies obtained higher academic performance than those who did not participate. However, the statistical analysis shows that some of the differences did not reach statistical significance.</p>
            <p> Although this issue is mentioned in the manuscript, the discussion could be more critical.</p>
            <p> It is recommended to: 
                <list list-type="bullet">
                    <list-item>
                        <p>discuss more thoroughly the absence of statistical significance in some analyses,</p>
                    </list-item>
                    <list-item>
                        <p>avoid overly optimistic interpretations of the results,</p>
                    </list-item>
                    <list-item>
                        <p>contextualize these findings within the broader literature on similar interventions.</p>
                    </list-item>
                </list> 3.4 Justification for the use of learning style instruments</p>
            <p> The study includes instruments such as: 
                <list list-type="bullet">
                    <list-item>
                        <p>VAK (perceptual channels)</p>
                    </list-item>
                    <list-item>
                        <p>CHAEA (learning styles)</p>
                    </list-item>
                </list> However, the results indicate that no significant relationship exists between these variables and academic performance.</p>
            <p> Furthermore, recent literature has questioned the pedagogical validity of the concept of learning styles.</p>
            <p> It is suggested to: 
                <list list-type="bullet">
                    <list-item>
                        <p>more clearly justify the use of these instruments, or</p>
                    </list-item>
                    <list-item>
                        <p>simplify this part of the analysis if it does not provide relevant evidence for the study.</p>
                    </list-item>
                </list> 3.5 Discussion of study limitations</p>
            <p> The discussion section should include a more explicit reflection on the limitations of the study.</p>
            <p> Among the main limitations that could be addressed are: 
                <list list-type="bullet">
                    <list-item>
                        <p>the relatively small size of the experimental group,</p>
                    </list-item>
                    <list-item>
                        <p>the absence of random assignment,</p>
                    </list-item>
                    <list-item>
                        <p>the limited duration of the intervention,</p>
                    </list-item>
                    <list-item>
                        <p>the possible self-selection bias in student participation.</p>
                    </list-item>
                </list> 4. Minor comments 
                <list list-type="order">
                    <list-item>
                        <p>Review some paragraphs in the theoretical framework to reduce repetition and improve argumentative clarity.</p>
                    </list-item>
                    <list-item>
                        <p>Improve transitions between some subsections of the introduction, particularly between sections addressing university dropout and assurance of learning.</p>
                    </list-item>
                    <list-item>
                        <p>Verify consistency in the use of terms such as:</p>
                    </list-item>
                </list> 
                <list list-type="bullet">
                    <list-item>
                        <p>
                            <italic>academic performance</italic>
                        </p>
                    </list-item>
                    <list-item>
                        <p>
                            <italic>academic success</italic>
                        </p>
                    </list-item>
                    <list-item>
                        <p>
                            <italic>learning assurance</italic>
                        </p>
                    </list-item>
                </list> 
                <list list-type="order">
                    <list-item>
                        <p>Revise the wording of certain paragraphs to improve conciseness and readability.</p>
                    </list-item>
                </list> Conclusion</p>
            <p> The manuscript presents a relevant and well-structured study on pedagogical strategies aimed at improving the learning outcomes of students at risk of academic failure in chemistry courses.</p>
            <p> The interventions described have practical value and potential for replication in other higher education institutions.</p>
            <p> However, before publication, the article requires some improvements in conceptual organization, methodological justification, and critical discussion of the results.</p>
            <p> </p>
            <p> Final recommendation:</p>
            <p> Accepted for indexing after moderate revisions.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Chemistry teaching, Science education; Biomaterials</p>
            <p>We confirm that we have read this submission and believe that we have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report453313">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.195364.r453313</article-id>
            <title-group>
                <article-title>Reviewer response for version 3</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Tr&#x010d;kov&#x00e1;</surname>
                        <given-names>Kate&#x0159;ina</given-names>
                    </name>
                    <xref ref-type="aff" rid="r453313a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8158-0307</uri>
                </contrib>
                <aff id="r453313a1">
                    <label>1</label>University of Ostrava, Ostrava, Czech Republic</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>4</day>
                <month>2</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Tr&#x010d;kov&#x00e1; K</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport453313" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.3"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The authors have successfully streamlined and simplified the introduction and added a concise summary table of didactic strategies, significantly improving the clarity of the manuscript; therefore, I recommend the article for indexing.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>My expertise lies in chemistry education and science didactics, with a particular focus on the design, implementation, and evaluation of innovative teaching strategies in chemistry. I have experience in developing and assessing active learning approaches, laboratory instruction, and educational interventions aimed at improving student engagement and performance in STEM subjects.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report436637">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.190331.r436637</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Asli</surname>
                        <given-names>Sare</given-names>
                    </name>
                    <xref ref-type="aff" rid="r436637a1">1</xref>
                    <xref ref-type="aff" rid="r436637a2">2</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3754-4613</uri>
                </contrib>
                <aff id="r436637a1">
                    <label>1</label>Science &amp; Technology, Al-Qasemi Academic College, Baqa El-Garbiah, Israel</aff>
                <aff id="r436637a2">
                    <label>2</label>Science Education, The Institute of Applied Research, Galilee Society, Shefa-'Amr, Israel</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>13</day>
                <month>1</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Asli S</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport436637" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This manuscript addresses an important and well-defined problem in higher education chemistry, focusing on strategies to support students at risk of academic failure. The study is grounded in a clear institutional context and aligns well with Assurance of Learning frameworks.</p>
            <p> The identification of at-risk students using national standardized test data (Saber 11) is appropriate and provides an objective basis for participant classification. The mixed-methods design is suitable, combining academic performance data with instructor and student perceptions. The statistical approach is clearly justified, and the use of non-parametric tests and effect sizes strengthens interpretation beyond p-values alone.</p>
            <p> The results are interpreted cautiously and appropriately. While whole-sample effects are limited, targeted analyses of at-risk students show meaningful educational benefits, particularly for the leveling course. The discussion avoids unsupported claims, and the conclusions are consistent with the data.</p>
            <p> 
                <bold>Minor amendments recommended:</bold> improving clarity by streamlining some sections of the introduction, adding a concise summary table of the didactic strategies to enhance replicability (without disclosing proprietary details), and ensuring consistent figure labeling and concise captions.</p>
            <p> Overall, the manuscript is methodologically sound, transparently reported, and makes a valuable contribution to chemistry education research. These minor revisions would further improve readability but do not affect the study's validity.</p>
            <p> 
                <bold>Recommendation: </bold>Approved with reservations.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Environmental Engineering, Agrobiology, Science Education for Sustainability, and Educational Methods in STEM</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment15282-436637">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Vera Monroy</surname>
                            <given-names>Sulma</given-names>
                        </name>
                        <aff>Universidad de La Sabana, Chia, Ch&#x00ed;a, Colombia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>16</day>
                    <month>1</month>
                    <year>2026</year>
                </pub-date>
            </front-stub>
            <body>
                <p>Dear Reviewer,</p>
                <p> Warm greetings. We sincerely appreciate the time and dedication you devoted to reviewing our manuscript. Your observations and suggestions were highly valuable and directly contributed to strengthening the clarity, coherence, and overall quality of the work.</p>
                <p> </p>
                <p> In response to your comments, we made targeted revisions to improve the clarity and flow of the introduction, avoiding repetition and prioritizing a more precise line of argumentation. In addition, we included a concise summary table of the didactic strategies while ensuring that no proprietary or sensitive information is disclosed. Finally, we reviewed and standardized the labeling of figures and tables and refined the figure and table titles to ensure consistency and greater conciseness.</p>
                <p> </p>
                <p> Sincerely,</p>
                <p> Authors</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report436638">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.190331.r436638</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Tr&#x010d;kov&#x00e1;</surname>
                        <given-names>Kate&#x0159;ina</given-names>
                    </name>
                    <xref ref-type="aff" rid="r436638a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8158-0307</uri>
                </contrib>
                <aff id="r436638a1">
                    <label>1</label>University of Ostrava, Ostrava, Czech Republic</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>2</day>
                <month>12</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Tr&#x010d;kov&#x00e1; K</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport436638" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The authors have addressed all previously raised concerns with clarity and precision. In version 2, the manuscript presents significant improvements in methodological transparency, statistical interpretation, and international readability. Participant group sizes are now explicitly reported, the grading scale is clearly explained, and additional details enable full replicability. The inclusion of effect sizes (Cohen&#x2019;s 
                <italic>d</italic>, 
                <italic>r</italic>) strengthens the interpretation of results, and the combined impact of both interventions is appropriately discussed. While full gamification materials remain under intellectual property protection, their structure and pedagogical rationale are sufficiently described. Notably, the manuscript now includes instructor perspectives and enhanced international references, which situate the study within a broader academic context. Claims in the conclusion have also been moderated in line with the presented data. In light of these improvements, I recommend the article be approved without reservations.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>My expertise lies in chemistry education and science didactics, with a particular focus on the design, implementation, and evaluation of innovative teaching strategies in chemistry. I have experience in developing and assessing active learning approaches, laboratory instruction, and educational interventions aimed at improving student engagement and performance in STEM subjects.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report403820">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.182065.r403820</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Asli</surname>
                        <given-names>Sare</given-names>
                    </name>
                    <xref ref-type="aff" rid="r403820a1">1</xref>
                    <xref ref-type="aff" rid="r403820a2">2</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3754-4613</uri>
                </contrib>
                <aff id="r403820a1">
                    <label>1</label>Science &amp; Technology, Al-Qasemi Academic College, Baqa El-Garbiah, Israel</aff>
                <aff id="r403820a2">
                    <label>2</label>Science Education, The Institute of Applied Research, Galilee Society, Shefa-'Amr, Israel</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>12</day>
                <month>9</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Asli S</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport403820" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The article is, for the most part, clearly written and logically structured, so I would rate the clarity and accuracy of presentation as 
                <underline>partly </underline>rather than a full yes. The introduction does a good job linking the institutional problem to the research interventions, but it is overly long and at times repeats ideas. Trimming this section and tightening the focus would keep the reader engaged and highlight the central research question more effectively. The literature cited is relevant to the topic and grounded in both national and international work, but some of it is dated. Bringing in more recent studies from 2022&#x2013;2024&#x2014;especially on gamification and academic leveling in STEM&#x2014;would both strengthen the theoretical base and broaden the paper&#x2019;s global relevance.</p>
            <p> </p>
            <p> Regarding the study design, I consider it appropriate and technically sound, though with minor reservations. The mixed-methods, quasi-experimental approach is well suited to an educational intervention where random assignment is impractical. The use of historical control data alongside a defined at-risk experimental group provides a solid comparative framework. However, the absence of a power calculation or sample size justification is a weakness. Including such a calculation&#x2014;or at least explaining why the chosen sample size is sufficient&#x2014;would reassure readers that the study was capable of detecting meaningful effects.</p>
            <p> </p>
            <p> When it comes to the level of methodological detail, I rate it as partly sufficient for full replication. The description of the two interventions is thorough enough for another instructor to reproduce them, and the open sharing of datasets and instruments via Zenodo is excellent. However, the rationale for the choice of statistical tests could be explained more explicitly. While it is mentioned that non-parametric tests were chosen due to non-normality, linking each test choice directly to the research questions and data characteristics would be helpful. It is also unclear whether any data were missing and, if so, how these were handled&#x2014;this is an important detail for anyone attempting to replicate the analysis.</p>
            <p> </p>
            <p> On the statistical analysis itself, I also answer partly. The selection of non-parametric tests is correct for the data distribution, and the results are clearly reported in terms of p-values. However, the absence of effect sizes means we cannot judge the magnitude of the improvements, which limits the practical interpretability of the results. Additionally, the paper refers to a possible &#x201c;synergistic effect&#x201d; when both strategies are combined, but no formal interaction test is presented. Including such a test would make this claim much stronger.</p>
            <p> For the question about whether all underlying data are available, my answer is a confident yes. The data and instruments are hosted on Zenodo, have functioning DOIs, and are released under a CC-BY license, which is excellent for transparency and reproducibility.</p>
            <p> </p>
            <p> Finally, regarding whether the conclusions are supported by the results, I would rate this as partly. The conclusion that the leveling course had the most impact is strongly supported by statistically significant results. The gamified kit&#x2019;s effect is positive, but smaller, and this should be described with a bit more nuance. The claim that these strategies could be applied successfully in other subjects is plausible but not tested in this study, so it should be framed as a recommendation for future research rather than as an established fact.</p>
            <p> In short, my main recommendations for improving the paper are: 
                <list list-type="order">
                    <list-item>
                        <p>Streamline the introduction and remove repeated points.</p>
                    </list-item>
                    <list-item>
                        <p>Update the literature with recent (2022&#x2013;2024) international studies on similar interventions.</p>
                    </list-item>
                    <list-item>
                        <p>Provide a power calculation or clear justification for the sample size.</p>
                    </list-item>
                    <list-item>
                        <p>Clarify how missing or incomplete data were handled.</p>
                    </list-item>
                    <list-item>
                        <p>Report effect sizes for all key comparisons.</p>
                    </list-item>
                    <list-item>
                        <p>Run an interaction test before claiming synergy between strategies.</p>
                    </list-item>
                    <list-item>
                        <p>Reframe the scalability claim as a future research direction.</p>
                    </list-item>
                </list> With these revisions, the manuscript would not only be methodologically stronger but also have greater appeal to an international readership, while still maintaining its strong local relevance.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Environmental Engineering, Agrobiology, Science Education for Sustainability, and Educational Methods in STEM</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment14848-403820">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Vera Monroy</surname>
                            <given-names>Sulma</given-names>
                        </name>
                        <aff>Universidad de La Sabana, Chia, Ch&#x00ed;a, Colombia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>25</day>
                    <month>10</month>
                    <year>2025</year>
                </pub-date>
            </front-stub>
            <body>
                <p>We thank the reviewer for these insightful suggestions. We implemented the following targeted revisions responding solely to this review: 
                    <list list-type="bullet">
                        <list-item>
                            <p>
                                <bold>Introduction: </bold>The Introduction was revised and condensed&#x00a0;to remove repeated ideas and maintain a sharper focus on the central research question. Recent international studies (2022&#x2013;2024)&#x00a0;on academic leveling and gamification in STEM education&#x00a0;were incorporated to update the theoretical framework and reinforce the global relevance of the study.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Methodology:</bold>&#x00a0;A new Statistical Approach and Justification&#x00a0;section was created to clarify the rationale&#x00a0;behind the selection of non-parametric tests and their alignment with the research questions. The total number of participants&#x00a0;and the size of each subgroup&#x00a0;(reinforcement course, gamified kit, and combined strategies) were reported to increase methodological transparency.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Results: </bold>The discussion of p-values&#x00a0;(Tables 6&#x2013;7 and 9) was expanded&#x00a0;to provide a clearer interpretation of statistical significance. In Table 10, Cohen&#x2019;s d&#x00a0;was added to report the effect size&#x00a0;and strengthen the interpretation of the results.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Conclusions</bold>: The effect of the gamified kit&#x00a0;was described with greater nuance, emphasizing its smaller magnitude relative to the reinforcement course. The claim about scalability&#x00a0;of the strategies was reframed as a recommendation for future research, rather than a generalizable conclusion.</p>
                        </list-item>
                    </list> </p>
                <p> Once again, we appreciate the reviewers&#x2019; thorough feedback and remain attentive to any further comments.</p>
            </body>
        </sub-article>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report403822">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.182065.r403822</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Tr&#x010d;kov&#x00e1;</surname>
                        <given-names>Kate&#x0159;ina</given-names>
                    </name>
                    <xref ref-type="aff" rid="r403822a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-8158-0307</uri>
                </contrib>
                <aff id="r403822a1">
                    <label>1</label>University of Ostrava, Ostrava, Czech Republic</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>4</day>
                <month>9</month>
                <year>2025</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Tr&#x010d;kov&#x00e1; K</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport403822" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.165428.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The article by Monsalve-Silva, Bermudez-Aponte, and Vera-Monroy presents a study on the implementation of didactic strategies aimed at students at risk of academic failure in general chemistry at Universidad de La Sabana. Two interventions were tested: a reinforcement course and a gamified kit for unit conversions. The mixed-methods quasi-experimental design, using 411 control students (2020&#x2013;2023) and 60 experimental students (2023&#x2013;2024), revealed improvements in academic performance, especially among students with low Saber 11 scores, as well as positive student perceptions. The topic is relevant, the interventions are innovative, and the paper provides valuable empirical evidence for assurance of learning processes in STEM higher education.</p>
            <p> Regarding the study design, it is overall appropriate and technically sound, but only partly satisfactory. The quasi-experimental mixed-methods approach is suitable for the problem, and the instruments used are valid. However, the lack of precise participant numbers in each intervention group (reinforcement course, gamified kit, both) weakens the technical rigor and complicates interpretation of results. The description of methods and analyses is also only partly sufficient to allow full replication. While the authors describe the instruments (VAK, CHAEA, MAI) and statistical tests (Mann-Whitney, Spearman, Kolmogorov-Smirnov), replication would require additional detail. In particular, the gamified kit is shown only through illustrations, not full materials; the number of participants per subgroup is not reported; and the interpretation of p-values is not explained in sufficient depth.</p>
            <p> The statistical analysis and its interpretation are likewise only partly appropriate. The choice of non-parametric tests is correct given the distribution of the data, but interpretation is limited. Effect sizes (e.g., Cohen&#x2019;s d, r) are not reported, and the significance of p-values is not clearly explained. In Table 9, none of the p-values reach conventional significance, yet the text suggests positive effects. The combined effect of both strategies is under-discussed, although the data indicate potentially interesting interactions.</p>
            <p> In contrast, all underlying source data have been made openly available on Zenodo under a CC-BY license, ensuring reproducibility. This is a strong aspect of the study and fully meets the requirements for data accessibility. As for the conclusions, they are supported by the results but only with some reservations. The claim that the reinforcement course significantly improves outcomes is well substantiated, and the positive effect of the gamified kit is reasonably supported. However, broader generalizations&#x2014;such as the assertion that these strategies can be scaled across all subjects&#x2014;go beyond the presented data and should be phrased more cautiously.</p>
            <p> Additional issues should also be addressed. The grading scale is not explained; international readers may be confused unless it is stated clearly that in Colombia grades range from 0&#x2013;5, with 5 as the highest and 3.0 as the minimum passing threshold. Tables would benefit from indicating the number of participants (N) per subgroup, and figure captions could provide more informative notes. More international references on remediation and gamification in higher education would help situate the study in a global context. Finally, the perspectives of instructors are missing; only student perceptions are reported, yet teacher views on feasibility and workload are critical for evaluating implementation.</p>
            <p> In summary, the study is scientifically valid, well-motivated, and presents meaningful findings. Nevertheless, to improve transparency, replicability, and international readability, the authors should provide subgroup sample sizes, clarify the grading scale, report effect sizes, and interpret p-values with more rigor. For these reasons, my recommendation is: Approved with reservations.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>My expertise lies in chemistry education and science didactics, with a particular focus on the design, implementation, and evaluation of innovative teaching strategies in chemistry. I have experience in developing and assessing active learning approaches, laboratory instruction, and educational interventions aimed at improving student engagement and performance in STEM subjects.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
        <sub-article article-type="response" id="comment14847-403822">
            <front-stub>
                <contrib-group>
                    <contrib contrib-type="author">
                        <name>
                            <surname>Vera Monroy</surname>
                            <given-names>Sulma</given-names>
                        </name>
                        <aff>Universidad de La Sabana, Chia, Ch&#x00ed;a, Colombia</aff>
                    </contrib>
                </contrib-group>
                <author-notes>
                    <fn fn-type="conflict">
                        <p>
                            <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                    </fn>
                </author-notes>
                <pub-date pub-type="epub">
                    <day>25</day>
                    <month>10</month>
                    <year>2025</year>
                </pub-date>
            </front-stub>
            <body>
                <p>We thank the reviewer for these precise and valuable suggestions. In response, several modifications were made to improve methodological clarity, statistical transparency, and contextual understanding: 
                    <list list-type="bullet">
                        <list-item>
                            <p>
                                <bold>Participants and subgroups:</bold>&#x00a0;The total number of students and the size of each subgroup (reinforcement course, gamified kit, and combined interventions) were added to the 
                                <italic>Methodology</italic>&#x00a0;section.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Procedures and implementation:</bold>&#x00a0;Additional detail was included regarding the classification of at-risk students, implementation period and frequency, and timing of the applied instruments to ensure reproducibility.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Grading scale:</bold>&#x00a0;A specific subsection explaining the Colombian 0&#x2013;5 grading system (with 3.0 as the minimum passing threshold) was incorporated to enhance international readability.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Statistical analysis:</bold>&#x00a0;A new 
                                <italic>Statistical Approach and Justification</italic>&#x00a0;section now elaborates on the rationale for the non-parametric tests used, expands the interpretation of p-values, and includes calculation of 
                                <bold>Cohen&#x2019;s d</bold>&#x00a0;to report effect sizes.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Tables:</bold>&#x00a0;Tables 6&#x2013;10 were updated to include the number of participants (N) per subgroup and to refine the discussion of p-values and observed effects.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Instructor perspectives:</bold>&#x00a0;A subsection summarizing teachers&#x2019; perceptions of feasibility and student engagement was incorporated to complement student perceptions.</p>
                        </list-item>
                        <list-item>
                            <p>
                                <bold>Conclusions:</bold>&#x00a0;The statements about replicability and scalability were rewritten to present a more cautious interpretation aligned with the evidence obtained.</p>
                        </list-item>
                    </list> These revisions directly address the reviewer&#x2019;s concerns, increasing the 
                    <bold>transparency, rigor, and international accessibility</bold>&#x00a0;of the study while preserving its applied focus within STEM higher education.</p>
            </body>
        </sub-article>
    </sub-article>
</article>
