<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.167870.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Suicidal behavior during the Covid-19 pandemic: Results from cross-sectional surveys of Brazilian adults from 2020 to 2022</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: awaiting peer review]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Faro</surname>
                        <given-names>Andre</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-7348-6297</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Palhano</surname>
                        <given-names>Dandara</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>dos Santos Silva</surname>
                        <given-names>Luanna</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Falk</surname>
                        <given-names>Derek</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-5929-8874</uri>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Psychology, Federal University of Sergipe, Aracaju, Sergipe, 49000-000, Brazil</aff>
                <aff id="a2">
                    <label>2</label>Public Health, The University of Texas at Arlington, Arlington, Texas, USA</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:andre.faro.ufs@gmail.com">andre.faro.ufs@gmail.com</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>8</month>
                <year>2025</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2025</year>
            </pub-date>
            <volume>14</volume>
            <elocation-id>835</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>19</day>
                    <month>8</month>
                    <year>2025</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2025 Faro A et al.</copyright-statement>
                <copyright-year>2025</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/14-835/pdf"/>
            <abstract>
                <sec>
                    <title>Objectives</title>
                    <p>This study aimed to analyze the predictive capacity of fear of Covid-19, anxiety and depressive symptoms, and pandemic year on suicidal behaviors in the years 2020, 2021, and 2022.</p>
                </sec>
                <sec>
                    <title>Methods</title>
                    <p>The total sample consisted of 7,746 adults from all regions of the country and over 1,300 Brazilian cities, with an average age of 34 years. The research instruments used were the Fear of Covid-19 Scale (FCV-19S), the Generalized Anxiety Disorder Scale (GAD-7), the Patient Health Questionnaire Scale (PHQ-9), and a question assessing the absence, presence of suicidal ideation, and suicide planning or attempts. Data analysis was conducted using multinomial logistic regression.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>The study&#x2019;s key findings revealed that fear of Covid-19 (severe [OR = 0.696]), along with varying levels of anxiety (mild [OR = 2.183], moderate [OR = 2.436], severe [OR = 2.757]) and depression (mild [OR = 2.831], moderate [OR = 4.769], severe [OR = 10.660]), were significantly associated with suicidal ideation. Predictors for suicide planning and attempts included the year (2022 [OR = 1.297]), fear of Covid-19 (moderate [OR = 0.614], severe [OR = 0.445]), anxiety (mild [OR = 2.253], moderate [OR = 2.988], severe [OR = 3.577]), and depression (mild [OR = 3.021], moderate [OR = 8.189], severe [OR = 40.363]).</p>
                </sec>
                <sec>
                    <title>Discussion</title>
                    <p>These findings underscore the importance of ongoing monitoring of the pandemic&#x2019;s impact, as mental health surveillance remains essential for shaping effective policies to address suicidal behavior.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Covid-19</kwd>
                <kwd>suicidal behavior</kwd>
                <kwd>fear of covid-19</kwd>
                <kwd>anxiety</kwd>
                <kwd>depression</kwd>
                <kwd>Advanced statistical analysis</kwd>
                <kwd>Suicide</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1">
                    <funding-source>Conselho Nacional de Desenvolvimento Cient&#x00ed;fico e Tecnol&#x00f3;gico</funding-source>
                </award-group>
                <award-group id="fund-2">
                    <funding-source>Coordena&#x00e7;&#x00e3;o de Aperfei&#x00e7;oamento de Pessoal de N&#x00ed;vel Superior</funding-source>
                </award-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>1. Introduction</title>
            <p>Even by early 2024, the Covid-19 pandemic remains a significant public health Iconcern, particularly due to its long-term psychological and social impacts (
                <xref ref-type="bibr" rid="ref32">National Institutes of Health, 2024</xref>; 
                <xref ref-type="bibr" rid="ref54">World Health Organization, 2023a</xref>). Although global infection and mortality rates have declined with widespread vaccination (
                <xref ref-type="bibr" rid="ref40">Rahmani et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref54">World Health Organization, 2023a</xref>), Covid-19 continues to affect healthcare systems, especially in Brazil (
                <xref ref-type="bibr" rid="ref8">Brasil. Minist&#x00e9;rio da Sa&#x00fa;de., 2023b</xref>; 
                <xref ref-type="bibr" rid="ref58">World Health Organization et al., 2023b</xref>). Understanding its repercussions is crucial, particularly regarding mental health and suicidal behavior, which became more prominent concerns between 2020 and 2022.</p>
            <p>Suicide prevention has been a global public health priority since the World Health Organization (WHO) highlighted it in 
                <xref ref-type="bibr" rid="ref57">2014</xref> (
                <xref ref-type="bibr" rid="ref56">World Health Organization, 2023d</xref>) yet, only a fraction of WHO member countries have implemented national strategies. Brazil adopted its National Policy for the Prevention of Self-Harm and Suicide in 2019 (
                <xref ref-type="bibr" rid="ref6">Brasil. Lei, 2019</xref>), shortly before the onset of the pandemic. This public health crisis reignited the urgency of suicide prevention, especially as prevalence patterns shifted during the pandemic&#x2019;s most critical phases (
                <xref ref-type="bibr" rid="ref35">Pan American Health Organization, 2020</xref>; 
                <xref ref-type="bibr" rid="ref59">Yan et al., 2023</xref>).</p>
            <p>In Brazil, the pandemic unfolded in three major waves, marked by peaks in mortality during mid-2020, early 2021, and early 2022. Regional disparities were notable, with initial impacts strongest in the North and Northeast, and the third wave showing the highest rates in the South. The launch of a national vaccination campaign in early 2021 helped reduce fatalities, though morbidity remained high (
                <xref ref-type="bibr" rid="ref31">Moura et al., 2022</xref>).</p>
            <p>Suicidal behavior includes a spectrum of actions such as ideation, planning, attempts, and completed suicide (
                <xref ref-type="bibr" rid="ref33">Nock et al., 2008a</xref>; 
                <xref ref-type="bibr" rid="ref56">World Health Organization, 2023d</xref>). Globally, around 700,000 people die by suicide each year (
                <xref ref-type="bibr" rid="ref55">World Health Organization, 2023c</xref>). While emerging research has examined the effects of Covid-19 on suicide-related outcomes, findings remain inconsistent (
                <xref ref-type="bibr" rid="ref38">Pirkis et al., 2021</xref>; 
                <xref ref-type="bibr" rid="ref59">Yan et al., 2023</xref>). Environmental stressors&#x2014;such as those imposed by a global pandemic&#x2014;are known to increase psychological distress and may elevate suicide risk (
                <xref ref-type="bibr" rid="ref16">Faro et al., 2020</xref>).</p>
            <p>Among these stressors, fear has played a central role. Defined as an adaptive response to perceived threat, fear can be protective but also harmful when excessive or prolonged (
                <xref ref-type="bibr" rid="ref1">Ahorsu et al., 2020</xref>; 
                <xref ref-type="bibr" rid="ref22">Harper et al., 2021</xref>). Studies have linked fear of Covid-19 to increased compliance with health measures (
                <xref ref-type="bibr" rid="ref22">Harper et al., 2021</xref>; 
                <xref ref-type="bibr" rid="ref27">Lin et al., 2021</xref>) but also to greater anxiety, depression, and suicidal behavior in countries like Taiwan and Spain (
                <xref ref-type="bibr" rid="ref3">Alimoradi et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref28">Lin et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref42">&#x015e;im&#x015f;ir et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref45">Soto-Sanz et al., 2021</xref>).</p>
            <p>The pandemic has also contributed to a global rise in mental health issues. Depression and anxiety&#x2014;both strong predictors of suicidal behavior&#x2014;increased significantly worldwide during the pandemic years (
                <xref ref-type="bibr" rid="ref10">Cheng et al., 2023</xref>; 
                <xref ref-type="bibr" rid="ref12">Daniali et al., 2023</xref>; 
                <xref ref-type="bibr" rid="ref53">World Health Organization, 2022a</xref>). In Brazil, studies from mid-2020 found moderate to severe anxiety in over 80% of cases and depression in 68% (
                <xref ref-type="bibr" rid="ref20">Goularte et al., 2021</xref>).</p>
            <p>Given these findings, this study aimed to assess how fear of Covid-19, anxiety, depression, and the specific year of the pandemic (2020, 2021, or 2022) predict suicidal behaviors in a sample of Brazilian adults.</p>
        </sec>
        <sec id="sec6">
            <title>2. Materials and Method</title>
            <sec id="sec7">
                <title>2.1 Participants</title>
                <p>The final sample consisted of responses to three cross-sectional surveys in the years 2020 (n = 4,803), 2021 (n = 1,477), and 2022 (n = 1,466), totaling 7,746 adults. The average age was 34.0 years (SD = 12.9; Min = 18 and Max = 70), with the majority being female (87.6%; n = 6,785), having a higher level of education (83.8%; n = 6,494), and identifying as white individuals (55.0%; n = 4,261). Participants were residents of approximately 1,300 Brazilian cities. The Northeast region was predominant (44.3%; n = 3,433), followed by the Southeast (34.3%; n = 2,657), South (12.3%; n = 950), Central-West (5.9%; n = 454), and North (3.3%; n = 252). 
                    <xref ref-type="table" rid="T1">
Table 1</xref> presents the distribution of all the collected sociodemographic data.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Sociodemographic profile (Brazil, n = 7,746).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Variables</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Total (n = 7,746)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">2020 (n = 4,803)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">2021 (n = 1,477)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
2022 (n = 1,466)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Age M (SD)</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">34.0 (12.9)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">31.3 (11.8)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">39.1 (13.4)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">37.8 (13.4)</td>
                            </tr>
                        </tbody>
                    </table>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">F% (n)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">F% (n)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">F% (n)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
F% (n)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Sex</bold>
</td>
                                <td colspan="4" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Male</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">12.4 (961)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">13.1 (628)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10.1 (149)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">12.6 (184)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Female</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87.6 (6,785)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">86.9 (4,175)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">89.9 (1,328)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">87.4 (1,282)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Skin color</bold>
</td>
                                <td colspan="4" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;White</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">55.0 (4,261)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52.3 (2,513)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">67.5 (997)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51.2 (751)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Black</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10.0 (774)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">11.6 (555)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6.8 (100)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8.1 (119)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Parda</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">35.0 (2,711)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">36.1 (1,735)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">25.7 (380)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">40.7 (596)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Educational level</bold>
</td>
                                <td colspan="4" rowspan="1"/>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Up to elementary school</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.7 (57)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.5 (22)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.4 (6)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.0 (29)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;High school</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">15.4 (1,195)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">23.2 (1,112)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.2 (17)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.5 (66)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Higher school</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">83.8 (6,494)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">76.4 (3,669)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">98.4 (1,454)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">93.5 (1,371)</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>Notes: M = Mean, SD = Standard deviation, F% = Percentual frequency, n = Absolute frequency.</p>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
            <sec id="sec8">
                <title>2.2 Instruments</title>
                <p>The Fear of Covid-19 Scale (FCV-19S) (
                    <xref ref-type="bibr" rid="ref1">Ahorsu et al., 2020</xref>) is a unidimensional scale containing seven items using a Likert scale from 1 (strongly disagree) to 5 (strongly agree). The total score is obtained by summing the items, with totals ranging from 7 to 35 points. In the adaptation study for Brazilian Portuguese, satisfactory psychometric results were found (
                    <xref ref-type="bibr" rid="ref18">Faro et al., 2022</xref>), and the level of fear was classified into three categories: 7 to 19 points as mild fear, 20 to 26 points as moderate, and 27 points and above as severe. In this study, the Cronbach&#x2019;s alpha (
                    <italic toggle="yes">&#x03b1;</italic>) was 0.87, and McDonald&#x2019;s omega (
                    <italic toggle="yes">&#x03c9;</italic>) was 0.88.</p>
                <p>The Generalized Anxiety Disorder Scale - 7 (GAD-7) (
                    <xref ref-type="bibr" rid="ref46">Spitzer et al., 2006</xref>) consists of seven items, which are answered on a scale from 0 (not at all) to 3 (nearly every day) points. The total score ranges from 0 to 21, and the level of anxiety is classified as minimal (0-4 points), mild (5-9 points), moderate (10-14 points), and severe (15-21 points). The psychometric properties and validity evidence for this scale in Brazil, assessed in its Brazilian Portuguese version, are considered satisfactory (
                    <xref ref-type="bibr" rid="ref30">Moreno et al., 2016</xref>). In this study, satisfactory internal consistency indices were found (
                    <italic toggle="yes">&#x03b1;</italic> = 0.89; 
                    <italic toggle="yes">&#x03c9;</italic> = 0.89).</p>
                <p>The Patient Health Questionnaire (PHQ-9) (
                    <xref ref-type="bibr" rid="ref26">Kroenke et al., 2001</xref>) consists of 9 items using a scale from 0 (not at all) to 3 (nearly every day). The total score ranges from a minimum of 0 to a maximum of 27. The stratification of scores proposes four categories: 0-4 as minimal, 5-9 as mild, 10-14 as moderate, and 15-27 as severe. The scale has demonstrated satisfactory psychometric characteristics in the Brazilian population in its Brazilian Portuguese version (
                    <xref ref-type="bibr" rid="ref4">Bergerot et al., 2014</xref>). In this study, the Cronbach&#x2019;s alpha and McDonald&#x2019;s omega were both 0.90.</p>
                <p>All Likert scales were analyzed using the simple summation of responses, followed by classification in accordance with the indicated references. Additionally, we ensured that the scoring adhered to established guidelines to maintain the integrity of our analysis.</p>
                <p>The sociodemographic questionnaire includes questions about the participant&#x2019;s sex (female or male), age (in years), skin color (white, black, parda [mixed ethnic heritage]), education level (up to elementary school, high school, or higher school), and city of residence. Participants were asked if at any point during the pandemic they had thoughts, plans, and/or attempts to end their own life, with the following response options: (0) Never, (1) I had only a brief passing thought, (2) I had a plan to end my life at least once, but I didn&#x2019;t attempt it, (3) I attempted to end my life, but didn&#x2019;t really want to die, and (4) I attempted to end my life and actually wanted to die.</p>
            </sec>
            <sec id="sec9">
                <title>2.3 Procedures</title>
                <p>Participant recruitment was conducted through convenience sampling, using social media platforms such as Facebook and Instagram. Posts on these platforms included links directing users to the research survey. Individuals who clicked on the link and voluntarily chose to participate became part of the study sample. This approach allowed the researchers to engage participants who were willing to take part in the research of their own accord. Only individuals aged 18 or older and those who agreed to the informed consent form, were eligible for the study. The consent was obtained electronically through the survey platform before the questionnaire was made available, which was presented at the beginning of the online questionnaire. Participation was voluntary, and anonymity and confidentiality were guaranteed in accordance with ethical standards. Data collection took place during three different periods of the pandemic in Brazil: June 2020, March 2021, and May 2022. The current findings have been reported in a preprint (
                    <xref ref-type="bibr" rid="ref17">Faro et al., 2024</xref>).</p>
            </sec>
            <sec id="sec10">
                <title>2.4 Data Analyses</title>
                <p>The Jamovi software (
                    <xref ref-type="bibr" rid="ref47">jamovi project, 2025</xref>, version 2.2.5) was used for data analyses. A hierarchical multinomial logistic regression was conducted with suicidal behavior as the dependent variable. This variable was recoded into the following groups:(1) absence of suicidal behavior; (2) presence of suicidal ideation; (3) suicide planning and/or attempt. The explanatory variables included the year of data collection (2020, 2021, 2022), and the levels of fear of Covid-19 (7-9 mild, 20-26 moderate, 27-35 severe), anxiety (0-4 no symptoms, 5-9 mild, 10-14 moderate, 15-21 severe), and depression (0-9 no symptoms, 10-14 mild, 15-19 moderate, 20-27 severe), added in this order to the model. Model fit evaluation criteria included the initial and final -2 log likelihood, the significance criteria (p 
                    <italic toggle="yes">&lt;</italic>
 0.05) of the odds ratios (OR), the model&#x2019;s predictive ability (correctly predicted cases, with values desired to be above 50%), the X
                    <sup>2</sup> (expected to be significant at p 
                    <italic toggle="yes">&lt;</italic>
 0.05), the Pearson Goodness of Fit X
                    <sup>2</sup> (expected value to be non-significant), and the Pseudo R-Square index (higher values indicate better fit). Odds ratios (OR) values below 1 were converted using the formula 1/OR for standardized result reporting.</p>
            </sec>
            <sec id="sec11">
                <title>2.5 Ethical consideration</title>
                <p>All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments. The study was approved by the National Commission of Research Ethics (CONEP) (Approval number: 3.955.180, Date: 01/05/2020). The consent was obtained electronically through the survey platform before the questionnaire was made available, which was presented at the beginning of the online questionnaire. Participation was voluntary, and anonymity and confidentiality were guaranteed in accordance with ethical standards.</p>
            </sec>
        </sec>
        <sec id="sec12" sec-type="results">
            <title>3. Results</title>
            <p>Over the three-year period of the study, the average score of the Fear of Covid-19 Scale (FCV-19S) was 22.6 (standard deviation [SD] = 6.05; median [Mdn] = 23.0), with the lowest average score in 2022 (Mdn = 20.0; mean [M] = 20.2; SD = 6.23) and the highest in 2021 (Mdn = 24.0; M = 23.9; SD = 5.6). In terms of severity, severe fear was proportionally higher in 2021 (34.6%, n = 511), as well as moderate fear in 2021 (44.3%, n = 654). The mild level had the highest value in 2022 (45.4%, n = 666). In total, there was a predominance of moderate fear (42.2%; n = 3,266). The GAD-7 had an overall average of 11.5 points (SD = 5.78; Mdn = 12.0), with the highest value in 2022 (Mdn = 13.0; M = 12.0; SD = 5.69). Only 12.5% (n = 970) did not exhibit significant anxiety symptoms, defined as moderate to severe anxiety, over the three years surveyed. The proportion of individuals classified with severe anxiety was highest in 2022 (39.0%; n = 572). In contrast, the number of participants at the mild level decreased from 2020 to 2022, dropping from 29.7% (n = 1,425) to 24.0% (n = 352).</p>
            <p>The average score of the PHQ-9 was 13.4 (SD = 7.44; Mdn = 13.0). In the total sample, 34.5% (n = 2,671) reported no significant depression symptoms, while the highest percentage of those with symptoms fell into the severe category (25.4%; n = 1,966). The highest average score was observed in 2022 (Mdn = 14.0; M = 13.9; SD = 7.61). The highest number of respondents with a severe score occurred in 2022 (29.7%; n = 435), the same year with the lowest number of respondents without depression (32.8%; n = 481). The presence of suicidal ideation, planning, or attempt occurred in 32.1% of the total sample (n = 2,488). Specifically, suicidal ideation fluctuated slightly, hovering around 20% from 2020 to 2022. However, suicide planning and/or attempts nearly doubled in value, going from almost 10% in 2020 to almost 17% in 2022. Additional details and values obtained in the samples are detailed in 
                <xref ref-type="table" rid="T2">
Table 2</xref>.</p>
            <table-wrap id="T2" orientation="portrait" position="float">
                <label>
Table 2. </label>
                <caption>
                    <title>Distribution of Suicidal Behavior Categories, Patient Health Questionnaire Scale (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and Fear of Covid-19 Scale (FCV-19S) scores.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="2" valign="top">Variables</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">Total</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">2020</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">2021</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
2022</th>
                        </tr>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">M (SD)</italic>
</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">M (SD)</italic>
</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">M (SD)</italic>
</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">M (SD)</italic>
</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>FCV-19S score</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">23.0; 22.6 (6.05)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">23.0; 22.9 (5.92)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">24.0; 23.9 (5.6)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.0; 20.2 (6.23)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>GAD score</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12.0; 11.5 (5.78)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">11.0; 11.2 (5.83)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12.0; 11.9 (5.64)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">13.0; 12.0 (5.69)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <bold>PHQ score</bold>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">13.0; 13.4 (7.44)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">13.0; 13.2 (7.39)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">13.0; 13.3 (7.40)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">14.0; 13.9 (7.61)</td>
                        </tr>
                    </tbody>
                </table>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top">
F% (n)</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
F% (n)</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
F% (n)</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
F% (n)</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="5" rowspan="1" valign="top">
                                <bold>Fear of Covid-19</bold>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Mild</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">30.3 (2,349)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">28.5 (1,371)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.1 (312)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">45.4 (666)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Moderate</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">42.2 (3,266)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">42.6 (2,048)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">44.3 (654)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">38.5 (564)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Severe</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">27.5 (2,131)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">28.8 (1,384)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">34.6 (511)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">16.1 (236)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="5" rowspan="1" valign="top">
                                <bold>Anxiety symptoms</bold>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;No</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12.5 (970)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">13.9 (666)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">9.9 (146)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">10.8 (158)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Mild</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">28.1 (2,173)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">29.7 (1,425)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">26.8 (396)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">24.0 (352)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Moderate</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">24.2 (1,878)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">23.1 (1,114)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">25.7 (380)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">26.2 (384)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Severe</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">35.2 (2,725)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">33.3 (1,598)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">37.6 (555)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">39.0 (572)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="5" rowspan="1" valign="top">
                                <bold>Depression symptoms</bold>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;No</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">34.6 (2,677)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">35.4 (1,702)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">33.4 (494)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">32.8 (481)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Mild</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">19.7 (1,524)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">19.3 (928)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.7 (321)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">18.8 (275)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Moderate</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.3 (1,576)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.9 (1,001)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.3 (300)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">18.8 (275)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Severe</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">25.4 (1,969)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">24.4 (1,172)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">24.5 (362)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">29.7 (435)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="5" rowspan="1" valign="top">
                                <bold>During the quarantine/social isolation, did you ever think about killing yourself or try to kill yourself?</bold>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Never</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">67.9 (5,258)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">69.8 (3,352)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">67.6 (998)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">61.9 (908)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;I had only a brief passing thought</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.8 (1,608)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.5 (986)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.0 (310)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.3 (312)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;I made a plan to kill myself at least once, but I didn&#x2019;t try</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">9.6 (745)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">8.7 (415)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">9.6 (143)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">12.8 (187)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;I tried to kill myself, but I didn&#x2019;t want to die</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.8 (62)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.6 (30)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.5 (8)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.6 (24)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;I tried to kill myself, and I really hoped to die</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.9 (73)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.4 (20)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">1.2 (18)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">2.4 (35)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="5" rowspan="1" valign="top">
                                <bold>Suicidal behavior</bold>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;No</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">67.9 (5,258)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">69.8 (3,352)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">67.6 (998)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">61.9 (908</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Ideation</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.8 (1,608)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">20.5 (986)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.0 (310)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">21.3 (312)</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x2003;Planning or attempt</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">11.4 (880)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">9.7 (465)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">11.4 (168)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">16.8 (246)</td>
                        </tr>
                    </tbody>
                </table>
                <table-wrap-foot>
                    <p>Notes: M = Mean, SD = Standard deviation, F% = Percentual frequency, n = Absolute frequency.</p>
                </table-wrap-foot>
            </table-wrap>
            <sec id="sec13">
                <title>3.1 Multinomial logistic regression</title>
                <p>The final model (
                    <xref ref-type="table" rid="T3">
Table 3</xref>) demonstrated an acceptable fit at all levels (p 
                    <italic toggle="yes">&lt;</italic>
 0.001). The model explained 20.7% of the variance (Nagelkerke&#x2019;s R
                    <sup>2</sup> = 0.207), and the correct predictive capacity had a total value of 34%. All the variables included remained as statistically significant in the final model.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Hierarchical Multinomial Multiple Regression - Reference group &#x201d;did not present suicidal ideation, planning, or attempt&#x201d; (Brazil, n = 7,746).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Suicidal behavior</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Predictor</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
Odds Ratio 
(CI95% LB-UB)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">
p-value
</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="4" rowspan="1" valign="top">
                                    <bold>Block 1 (R</bold>
                                    <sup>

                                        <bold>2</bold>
                                    </sup> 
                                    <bold>= 0.005)</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Suicidal ideation</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.056 (0.913 &#x2013; 1.222)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.465</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.168 (1.009 &#x2013; 1.353)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.038</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <bold>Suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.221 (1.010 &#x2013; 1.476)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.039</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.953 (1.646 &#x2013; 2.317)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="4" rowspan="1" valign="top">
                                    <bold>Block 2 (R</bold>
                                    <sup>

                                        <bold>2</bold>
                                    </sup> 
                                    <bold>= 0.015)</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="4" valign="top">
                                    <bold>Suicidal ideation</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.015 (0.876 &#x2013; 1.175)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.843</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.288 (1.109 &#x2013; 1.495)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.402 (1.218 &#x2013; 1.615)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.876 (1.610 &#x2013; 2.185)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="4" valign="top">
                                    <bold>Suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.180 (0.975 &#x2013; 1.428)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.089</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.122 (1.782 &#x2013; 2.527)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear&#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.056 (1.782 &#x2013; 2.527)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.549</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.758 (1.457 &#x2013; 2.121)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="4" rowspan="1" valign="top">
                                    <bold>Block 3 (R</bold>
                                    <sup>

                                        <bold>2</bold>
                                    </sup> 
                                    <bold>= 0.111)</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="7" valign="top">
                                    <bold>Suicidal ideation vs. Does not have suicidal ideation or suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.974 (0.837 &#x2013; 1.133)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.734</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.033 (0.883 &#x2013; 1.207)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.683</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.919 (0.790 &#x2013; 1.069) 
                                    <italic toggle="yes">[1.088 (0.935 &#x2013; 1.265</italic>)]
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.272</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.759 (0.638 &#x2013; 0.903) 
                                    <italic toggle="yes">[1.317 (1.107 &#x2013; 1.567)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.002</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.486 (2.535 &#x2013; 4.794)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">7.028 (5.111 &#x2013; 9.663)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">13.515 (9.839 &#x2013; 18.563)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="7" valign="top">
                                    <bold>Suicide planning and/or attempt vs. Does not have suicidal ideation or suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.118 (0.917 &#x2013; 1.363)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.268</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.562 (1.297 &#x2013; 1.880)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.619 (0.510 &#x2013; 0.750) 
                                    <italic toggle="yes">[1.615 (1.333 &#x2013; 1.960)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.530 (0.428 &#x2013; 0.655) 
                                    <italic toggle="yes">[1.886 (1.526 &#x2013; 2.336)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild anxiey &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.485 (2.489 &#x2013; 8.078)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">14.597 (8.220 &#x2013; 25.916)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">41.533 (23.513 &#x2013; 73.364)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="4" rowspan="1" valign="top">
                                    <bold>Block 4 (R</bold>
                                    <sup>

                                        <bold>2</bold>
                                    </sup> 
                                    <bold>= 0.207)</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="10" valign="top">
                                    <bold>Suicidal ideation vs. Does not have suicidal ideation or suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.062 (0.907 &#x2013; 1.243)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.453</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.087 (0.924 &#x2013; 1.278)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.313</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear&#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.917 (0.784 &#x2013; 1.072) 
                                    <italic toggle="yes">[1.090 (0.932 &#x2013; 1.275)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.280</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.696 (0.581 &#x2013; 0.833) 
                                    <italic toggle="yes">[1.436 (1.200 &#x2013; 1.721)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild anxiey &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.183 (1.566 &#x2013; 3.042)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.436 (1.719 &#x2013; 3.451)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.757 (1.928 &#x2013; 3.943)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.831 (2.290 &#x2013; 3.499)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4.769 (3.837 &#x2013; 5.927)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10.660 (8.492 &#x2013; 13.382)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="10" valign="top">
                                    <bold>Suicide planning and/or attempt vs. Does not have suicidal ideation or suicide planning and/or attempt</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.297 (1.050 &#x2013; 1.602)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.016</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022 &#x2013; 2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.644 (1.346 &#x2013; 2.007)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate fear&#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.614 (0.499 &#x2013; 0.755) 
                                    <italic toggle="yes">[1.560 (1.324 &#x2013; 2.004)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe fear &#x2013; Mild fear</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.445 (0.354 &#x2013; 0.559) 
                                    <italic toggle="yes">[2.247 (1.788 &#x2013; 2.824)]</italic>
                                    <xref ref-type="table-fn" rid="tfn1">*</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild anxiey &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.253 (1.210 &#x2013; 4.194)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.010</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2.988 (1.591 &#x2013; 5.613)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe anxiety &#x2013; No anxiety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.577 (1.897 &#x2013; 6.741)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mild depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3.021 (1.990 &#x2013; 4.588)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Moderate depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8.189 (5.516 &#x2013; 12.155)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Severe depression &#x2013; No depression</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">40.363 (27.341 &#x2013; 59.587)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">&lt;</italic>0.001</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>
Table notes Confidence Interval (LB = lower bound; UB = upper bound). AIC initial = 12,914; AIC final = 10,848 (
                            <italic toggle="yes">&#x03b4;</italic>AIC = 2.066) BIC initial = 12,956; BIC final = 11,001 Model comparisons 1 &#x2013; 2 [
                            <italic toggle="yes">&#x03c7;</italic>
                            <sup>2</sup> = 95.4(4); p 
                            <italic toggle="yes">&lt;</italic>
 0.001]; 2 &#x2013; 3 [
                            <italic toggle="yes">&#x03c7;</italic>
                            <sup>2</sup> = 987.5(6); p 
                            <italic toggle="yes">&lt;</italic>
 0.001]; 3 &#x2013; 4 [
                            <italic toggle="yes">&#x03c7;</italic>
                            <sup>2</sup> = 1015.5(6); p 
                            <italic toggle="yes">&lt;</italic>
 0.001].</p>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>1/OR (italic).</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <p>

                    <italic toggle="yes">Block 1: Year</italic>
                </p>
                <p>The first block, which included the year of data collection, demonstrated an adequate fit indicator [
                    <italic toggle="yes">&#x03c7;</italic>
                    <sup>2</sup> = 56.4 (4); p 
                    <italic toggle="yes">&lt;</italic>
 0.001]. In 2022, there was an additive impact, increasing the odds of being in the group with suicidal ideation by 16.8% (OR = 1.168; p = 0.038) and nearly doubling the odds of suicide planning and/or attempt (OR = 1.953; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) compared to the year 2020 (OR = 1.221; p 
                    <italic toggle="yes">&lt;</italic>
 0.039). There was no statistically significant difference in suicidal ideation between 2021 and 2020 (
                    <italic toggle="yes">p</italic>
 &#x2264; 0.05).</p>
                <p>

                    <italic toggle="yes">Block 2: Fear of Covid-19</italic>
                </p>
                <p>The second block also showed an adequate fit indicator for the FCV-19S scale [
                    <italic toggle="yes">&#x03c7;</italic>
                    <sup>2</sup> = 95.4 (4); p 
                    <italic toggle="yes">&lt;</italic>0.001]. Individuals with severe fear (OR = 1.876; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) or moderate fear (OR = 1.402; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) had a higher chance of being in the group with suicidal ideation compared to those with mild fear. In this block, the year variable remained significant for 2022, and there was an increase in the odds for both suicidal ideation and suicide planning and/or attempts.</p>
                <p>

                    <italic toggle="yes">Block 3: Anxiety</italic>
                </p>
                <p>In this block, there were also appropriate fit indicators for the GAD-7 scale [
                    <italic toggle="yes">&#x03c7;</italic>
                    <sup>2</sup> = 987.5 (6); p 
                    <italic toggle="yes">&lt;</italic>
 0.001]. However, in this block, the direction of the FCV-19S had reversed compared to the second block. The severe fear group had a lower chance of being in the groups with suicidal ideation and suicide planning and/or attempts when compared to mild fear by 31.7% (1/OR = 1.317; p = 0.002) and 88.6% (1/OR = 1.886; p 
                    <italic toggle="yes">&lt;</italic>
 0.001), respectively. The year variable was only significant for regarding suicide planning and/or attempts for 2022, showing a reduction in odds compared to the second block by almost two times to 56.2%, when comparing the 2022 to 2020 (OR = 1.562; p 
                    <italic toggle="yes">&lt;</italic>
 0.001).</p>
                <p>The anxiety variable increased the odds of suicidal ideation from three and a half times at the mild anxiety level (OR = 3.486; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) to over 13 times at the severe anxiety level (OR = 13.515; p 
                    <italic toggle="yes">&lt;</italic>
 0.001). For suicide planning and/or attempts, this range was from four and a half times at the mild anxiety level (OR = 4.485; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) to over 41 times at the severe anxiety level (OR = 41.533; p 
                    <italic toggle="yes">&lt;</italic>
 0.001), compared to the group without anxiety.</p>
                <p>

                    <italic toggle="yes">Block 4: Depression</italic>
                </p>
                <p>The fit indicators were significant for the PHQ-9 scale [
                    <italic toggle="yes">&#x03c7;</italic>
                    <sup>2</sup> = 1015.5 (6); p 
                    <italic toggle="yes">&lt;</italic>
 0.001]. The year 2022 had an increase of 64.4% for suicide planning and/or attempts (OR = 1.644; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) compared to the year 2020. The fear variable remained significant in the following models. The more severe the fear, the lower the chance of being among those with suicidal ideation, with values of 43.6% (1/OR = 1.436; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) for severe fear compared to mild fear. The same pattern was observed for suicide planning and suicidal ideation, with the values of 1/OR increasing from 1.886 to over two times (1/OR = 2.247; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) for severe fear compared to mild fear. Moderate fear remained stable in terms of values from the third to the fourth block.</p>
                <p>In the fourth block, the adjusted odds of the anxiety variable decreased compared to the third block, specifically for suicidal ideation. The results ranged from two times (OR = 2.183; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) to approximately three times (OR = 2.757; p 
                    <italic toggle="yes">&lt;</italic>
 0.001). For suicide planning and/or attempts, the behavior of the variable was the same, with results between two times (OR = 2.253; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) and over three times (OR = 3.577; p 
                    <italic toggle="yes">&lt;</italic>
 0.001).</p>
                <p>With the addition of the depression variable in this block and the adjustment of odds for suicidal ideation, the probabilities ranged from almost three times (OR = 2.831; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) to over ten times (OR = 10.660; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) in comparison to the group without depression. The same pattern occurred when considering the suicide planning and/or attempts group, with the odds increasing from three times (OR = 3.021; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) to over 40 times (OR = 40.363; p 
                    <italic toggle="yes">&lt;</italic>
 0.001) when compared to the group without depression.</p>
                <p>In summary, the cumulative impact of 2022 compared to 2020 was significant for suicidal behaviors in the first block. In the second block, the exposure factor of fear of Covid-19 was noteworthy, as the group of people with severe fear exhibited lower chances of displaying suicidal behaviors than those with mild fear. In the third block, the fear of Covid-19 reversed the direction of the relationship with the inclusion of anxiety and became a protective factor for the suicide behaviors. Moreover, the presence of anxiety in this block increased the chances of displaying suicide planning and/or attempts from over four times to 41 times compared to the group without anxiety. Finally, in the fourth block, the odds of anxiety were adjusted compared to the previous block. Considering the suicide planning and/or attempts group, the presence of depression increased the odds from three times to over 40 times compared to the group without depression.</p>
                <p>Evaluations of hierarchical multinomial logistic analyses and various indicators (VIF, tolerance, residuals, and the discrepancy of OR in relation to their confidence intervals) did not indicate unsatisfactory quality of the findings. 
                    <xref ref-type="fig" rid="f1">
Figure 1</xref> represents the last block of analysis, containing the adjusted ORs and their respective confidence intervals.</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>
Figure 1. </label>
                    <caption>
                        <title>Odds ratio and confidence intervals of the fourth block (last model) - Multinomial logistic regression for suicidal behavior (Brazil, n = 7,746).</title>
                        <p>

                            <italic toggle="yes">Notes.</italic> Graphical representations of OR and 95% CI in block 4 by variable. Panel 1A: Year of Pandemic. Panel 1B: Fear of Covid-19. Panel 1C: Anxiety Symptomatology. Panel 1D: Depression Symptomatology. &#x201c;a&#x201d; indicates statistically non-significant associations; all other values are statistically significant.</p>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/185014/e9fd7ce3-c221-40a9-b67e-1dcdc501162c_figure1.gif"/>
                </fig>
            </sec>
        </sec>
        <sec id="sec14" sec-type="discussion">
            <title>4. Discussion</title>
            <p>This study analyzed the predictive capacity of fear of Covid-19, anxiety, and depression on suicidal behaviors from 2020 to 2022. The average FCV- 19S score (M = 22.6; SD = 6.04) was higher than the global average reported in a meta-analysis across 36 countries (M = 13.11) (
                <xref ref-type="bibr" rid="ref3">Alimoradi et al., 2022</xref>).</p>
            <p>The peak of fear occurred in 2021, coinciding with the most severe phase of the pandemic in Brazil. This aligns with national mortality records and the healthcare system collapse (
                <xref ref-type="bibr" rid="ref23">Instituto Brasileiro de Geografia e Estat&#x00ed;stica, 2023</xref>; 
                <xref ref-type="bibr" rid="ref24">Instituto Butantan, 2021</xref>). By 2022, fear levels decreased, likely reflecting progress in vaccination and the easing of restrictions (
                <xref ref-type="bibr" rid="ref7">Brasil. Minist&#x00e9;rio da Sa&#x00fa;de., 2023a</xref>; 
                <xref ref-type="bibr" rid="ref9">Castro-Nunes and Ribeiro, 2022</xref>; 
                <xref ref-type="bibr" rid="ref25">Instituto Butantan, 2022</xref>; 
                <xref ref-type="bibr" rid="ref39">Poiatti and Pedroso, 2023</xref>).</p>
            <p>Anxiety and depression scores increased over the years, with 2022 showing the highest averages and severity rates. Significant symptoms were present in most of the sample (anxiety: 87.5%; depression: 65.4%). This is consistent with studies reporting higher prevalence in Latin America during the pandemic (
                <xref ref-type="bibr" rid="ref48">Torrente et al., 2023</xref>; 
                <xref ref-type="bibr" rid="ref60">Zhang et al., 2022</xref>), influenced by high mortality, socioeconomic instability, and political distrust.</p>
            <p>From 2020 to 2022, anxiety rose from 11.2 to 12.0, and depression from 13.2 to 13.9. The persistence of psychological distress suggests depletion of coping resources over time (
                <xref ref-type="bibr" rid="ref11">Cohen et al., 2019</xref>; 
                <xref ref-type="bibr" rid="ref37">Pfefferbaum and North, 2020</xref>; 
                <xref ref-type="bibr" rid="ref50">Vadivel et al., 2021</xref>). Suicidal behaviors also increased, especially planning/attempting suicide, which rose from 9.7% to 16.8%. While early stages may have been marked by collective resilience, longer-term stress appeared to heighten vulnerability (
                <xref ref-type="bibr" rid="ref43">Sinyor et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref49">Ueda et al., 2022</xref>; 
                <xref ref-type="bibr" rid="ref59">Yan et al., 2023</xref>).</p>
            <sec id="sec15">
                <title>4.1 Predictive variables of the suicidal behavior</title>
                <p>Suicidal ideation increased by 16.8% between 2020 and 2022, and suicide planning/attempt nearly doubled. These findings align with research warning of delayed mental health consequences of the pandemic (
                    <xref ref-type="bibr" rid="ref5">Bigoni et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref14">Dub&#x00e9; et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref15">Efstathiou et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref21">Gramacho and Turgeon, 2021</xref>). Initially, fear of Covid-19 was associated with higher suicidal ideation. However, once anxiety was included in the regression model, fear became a protective factor. This suppressor effect suggests that while persistent fear may initially be harmful, it may promote adaptive behaviors when controlling for anxiety (
                    <xref ref-type="bibr" rid="ref22">Harper et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref27">Lin et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref44">Smith et al., 1992</xref>). The fear variable maintained its relevance across years, although with lower explanatory power.</p>
                <p>Anxiety was strongly associated with suicidal ideation and behavior, increasing odds by up to tenfold for ideation and over 40 times for planning/attempting suicide. Given that nearly one-third of adults experienced anxiety during the pandemic (
                    <xref ref-type="bibr" rid="ref13">Delpino et al., 2022</xref>), this reinforces the urgent need for targeted mental health support.</p>
                <p>Depression emerged as the most significant predictor. Its inclusion in the model reduced the impact of year, fear, and anxiety variables. Suicidal ideation odds ranged from three to ten times higher depending on symptom severity; for planning/attempting suicide, the risk increased by over 40 times. These findings highlight the need to prioritize depression in suicide prevention strategies (
                    <xref ref-type="bibr" rid="ref2">Ali et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref12">Daniali et al., 2023</xref>; 
                    <xref ref-type="bibr" rid="ref19">Garc&#x00ed;a-Iglesias et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref29">Mann et al., 2005</xref>; 
                    <xref ref-type="bibr" rid="ref34">Nock et al., 2008b</xref>).</p>
                <p>This study supports global findings on the impact of the pandemic on mental health and suicidal behavior (
                    <xref ref-type="bibr" rid="ref29">Mann et al., 2005</xref>; 
                    <xref ref-type="bibr" rid="ref41">Robinson et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref51">Vandamme et al., 2023</xref>). The model&#x2019;s total predictive capacity reached 34% when combining all variables. Notably, fear showed dual roles&#x2014;risk factor when isolated, protective when anxiety was included&#x2014;requiring nuanced interpretation.</p>
                <p>Limitations include the use of a convenience, online sample and the inability to control for variables like age, gender, and socioeconomic status due to sample imbalance. However, the large sample (from over 1,300 cities) partially mitigates concerns about representativeness.</p>
                <p>Although Covid-19 is no longer considered a public health emergency (
                    <xref ref-type="bibr" rid="ref56">World Health Organization, 2023d</xref>), its mental health repercussions persist (
                    <xref ref-type="bibr" rid="ref36">Penninx et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref56">World Health Organization, 2023d</xref>). Suicide prevention remains essential. Individuals with depressive and anxiety symptoms&#x2014;key predictors in this study&#x2014;should receive prioritized support, in line with WHO guidelines (
                    <xref ref-type="bibr" rid="ref52">World Health Organization, 2022</xref>).</p>
            </sec>
        </sec>
        <sec id="sec16">
            <title>Ethics and consent</title>
            <p>All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments. The study was approved by the National Commission of Research Ethics (CONEP) (Approval number: 3.955.180, Date: 01/05/2020). The consent was obtained electronically through the survey platform before the questionnaire was made available, which was presented at the beginning of the online questionnaire. Participation was voluntary, and anonymity and confidentiality were guaranteed in accordance with ethical standards.</p>
        </sec>
        <sec id="sec17">
            <title>Software availability
</title>
            <p>

                <list list-type="bullet">
                    <list-item>
                        <label>&#x2022;</label>
                        <p>Source code available from: 
                            <ext-link ext-link-type="uri" xlink:href="https://www.jamovi.org">https://www.jamovi.org</ext-link>
                        </p>
                    </list-item>
                    <list-item>
                        <label>&#x2022;</label>
                        <p>Archived source code available from: Not applicable. The jamovi software is open-source and publicly available; no custom code was developed for this study.</p>
                    </list-item>
                    <list-item>
                        <label>&#x2022;</label>
                        <p>License: GNU General Public License v2.0 or later.</p>
                    </list-item>
                </list>
            </p>
        </sec>
        <sec id="sec18">
            <title>Declarations</title>
            <sec id="sec19">
                <title>Informed consent statement</title>
                <p>All participants were informed about the objectives of the study and provided their consent prior to participation. Consent was obtained electronically through the survey platform before the questionnaire was made available. Participation was voluntary, and anonymity and confidentiality were guaranteed in accordance with ethical standards.</p>
            </sec>
        </sec>
        <sec id="sec21">
            <title>Institutional review board statement: &#x2611;
</title>
            <p>

                <list list-type="alpha-lower">
                    <list-item>
                        <label>(a)</label>
                        <p>&#x2611; The study was conducted in accordance with the Declaration of Helsinki and was approved by an Institutional Review Board/Ethics committee. See details under Methods.</p>
                    </list-item>
                    <list-item>
                        <label>(b)</label>
                        <p>The study received an exemption from an Institutional Review Board/Ethics committee; See details under Methods.</p>
                    </list-item>
                </list>
            </p>
        </sec>
        <sec id="sec22">
            <title>Declaration of generative AI and AI-assisted technologies in the writing process</title>
            <p>The author(s) declare that no generative AI or AI-assisted technologies were used in the preparation of this manuscript.</p>
        </sec>
    </body>
    <back>
        <sec id="sec25" sec-type="data-availability">
            <title>Data availability statement</title>
            <p>The data that support the findings of this study cannot be shared publicly due to ethical restrictions, and the fact that the database is part of an ongoing longitudinal project with continuous data collection. According to the approval granted by the National Commission of Research Ethics (CONEP) (Approval number: 3.955.180, Date: 01/05/2020), public sharing of the dataset is not permitted in order to protect participant confidentiality and avoid compromising the integrity of the ongoing study.</p>
            <p>Researchers who meet the criteria for access to confidential data may submit a formal request to the corresponding author (
                <email xlink:href="mailto:andre.faro.ufs@gmail.com">andre.faro.ufs@gmail.com</email>) and will be required to sign a data use agreement. Requests will be evaluated by the research team, and access will only be granted under conditions that ensure compliance with ethical and security guidelines. No underlying or extended data are openly available for this study.</p>
        </sec>
        <sec id="sec26" sec-type="data-availability">
            <title>Data availability statement</title>
            <p>The data that support the findings of this study cannot be shared publicly due to ethical restrictions, and the fact that the database is part of an ongoing longitudinal project with continuous data collection. According to the approval granted by the National Commission of Research Ethics (CONEP) (Approval number: 3.955.180, Date: 01/05/2020), public sharing of the dataset is not permitted in order to protect participant confidentiality and avoid compromising the integrity of the ongoing study.</p>
            <p>Researchers who meet the criteria for access to confidential data may submit a formal request to the corresponding author (
                <email xlink:href="mailto:andre.faro.ufs@gmail.com">andre.faro.ufs@gmail.com</email>) and will be required to sign a data use agreement. Requests will be evaluated by the research team, and access will only be granted under conditions that ensure compliance with ethical and security guidelines. No underlying or extended data are openly available for this study.</p>
        </sec>
        <ack>
            <title>Acknowledgements</title>
            <p>Andr&#x00e9; Faro is a recipient of a Research Fellowship from the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cient&#x00ed;fico e Tecnol&#x00f3;gico &#x2013; CNPq, Brazil) and a Grant also provided by the CNPq, which supported to the development of this study.</p>
        </ack>
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