<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.174712.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Bayesian expectile regression with single-index models</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: awaiting peer review]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Abdulhasan</surname>
                        <given-names>Zina</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0009-0001-0738-3046</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Alhamzawi</surname>
                        <given-names>Rahim</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Department of Statistics, College of Administration and Economics, University of Al-Qadisiyah, Al Diwaniyah, Iraq</aff>
                <aff id="a2">
                    <label>2</label>Department of Statistics, College of Administration and Economics, University of Al-Qadisiyah, Al Diwaniyah, Iraq</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:statistics.stp.25.8@qu.edu.iq">statistics.stp.25.8@qu.edu.iq</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>15</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2026</year>
            </pub-date>
            <volume>15</volume>
            <elocation-id>516</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>20</day>
                    <month>2</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Abdulhasan Z and Alhamzawi R</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/15-516/pdf"/>
            <abstract>
                <p>Single-index expectile regression models provide a flexible semiparametric regression framework for high-dimensional covariates, and capture parameter heterogeneity and nonlinearity especially when focusing on different parts of the conditional distribution of the outcome of interest. Bayesian approaches have never been studied for such regression models. In this paper, we propose a Bayesian single-index expectile regression model using the asymmetric normal distribution (AND) for the error distribution. We design an MCMC method for posterior estimate. Simulations and real data analysis results show that the proposed approach performs very well compared with some existing approaches.</p>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Bayesian inference</kwd>
                <kwd>Expectile regression</kwd>
                <kwd>Single-index model</kwd>
                <kwd>Asymetric Normal Distribution</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec1" sec-type="intro">
            <title>1. Introduction</title>
            <p>Expectiles of a probability distribution F, like the quantiles of a probability distribution F, represent different points of a distribution, but they are determined by tail expectations rather than tail probabilities. Expectiles depend on both the tail realizations and their probability, while quantiles only depend on the frequency of tail observations. There exists an one-to-one mapping from expectiles to quantiles,
                <sup>
                    <xref ref-type="bibr" rid="ref26">27</xref>
                </sup> i.e. for each 
                <italic toggle="yes">&#x03c4;</italic>th expectile, there is a corresponding 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03b8;</mml:mi>
                    </mml:math>
</inline-formula>th quantile, where 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula> and 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03b8;</mml:mi>
                        <mml:mspace width="0.25em"/>
                        <mml:mo>&#x2208;</mml:mo>
                        <mml:mspace width="0.25em"/>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mn>0</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>1</mml:mn>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula>. Hence, expectiles can be utilized to estimate quantiles.</p>
            <p>The 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula>th expectile of 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>F</mml:mi>
                    </mml:math>
</inline-formula> is the quantity 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>e</mml:mi>
                            <mml:mi>&#x03c4;</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula> that satisfies
                <disp-formula id="e1">

                    <mml:math display="block">
                        <mml:mi>&#x03c4;</mml:mi>
                        <mml:mo>=</mml:mo>
                        <mml:mfrac>
                            <mml:mrow>
                                <mml:msubsup>
                                    <mml:mo>&#x222b;</mml:mo>
                                    <mml:mrow>
                                        <mml:mo>&#x2212;</mml:mo>
                                        <mml:mo>&#x221e;</mml:mo>
                                    </mml:mrow>
                                    <mml:msub>
                                        <mml:mi>e</mml:mi>
                                        <mml:mi>&#x03c4;</mml:mi>
                                    </mml:msub>
                                </mml:msubsup>
                                <mml:mrow>
                                    <mml:mo>|</mml:mo>
                                    <mml:mi>x</mml:mi>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:msub>
                                        <mml:mi>e</mml:mi>
                                        <mml:mi>&#x03c4;</mml:mi>
                                    </mml:msub>
                                    <mml:mo>|</mml:mo>
                                </mml:mrow>
                                <mml:mi mathvariant="italic">dF</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mi>x</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                            </mml:mrow>
                            <mml:mrow>
                                <mml:msubsup>
                                    <mml:mo>&#x222b;</mml:mo>
                                    <mml:mrow>
                                        <mml:mo>&#x2212;</mml:mo>
                                        <mml:mo>&#x221e;</mml:mo>
                                    </mml:mrow>
                                    <mml:mo>&#x221e;</mml:mo>
                                </mml:msubsup>
                                <mml:mo>|</mml:mo>
                                <mml:mi>x</mml:mi>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:msub>
                                    <mml:mi>e</mml:mi>
                                    <mml:mi>&#x03c4;</mml:mi>
                                </mml:msub>
                                <mml:mo>|</mml:mo>
                                <mml:mi mathvariant="italic">dF</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mi>x</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                            </mml:mrow>
                        </mml:mfrac>
                    </mml:math>

                    <label>(1)</label>
</disp-formula>
            </p>
            <p>Expectiles are a generalization of the mean and the expectile loss is a generalization of the mean squared error in the same way as quantiles are a generalization of the median and the quantile loss is a generalization of the mean absolute error. Standard regression model aims to estimate the conditional expectation of the outcome variable 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>y</mml:mi>
                    </mml:math>
</inline-formula> given the vector of covariates 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>x</mml:mi>
                        <mml:mo>,</mml:mo>
                        <mml:mi>i</mml:mi>
                        <mml:mo>.</mml:mo>
                        <mml:mi>e</mml:mi>
                        <mml:mo>.</mml:mo>
                        <mml:mo>,</mml:mo>
                        <mml:mi>E</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>y</mml:mi>
                            <mml:mo>|</mml:mo>
                            <mml:mi>x</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula>. In many applications, however, it is required to study conditional distributions beyond the mean (conditional expectation). A nice tool for this purpose was offered by
                <sup>
                    <xref ref-type="bibr" rid="ref16">17</xref>
                </sup> in the form of expectile regression. Expectile regression
                <sup>
                    <xref ref-type="bibr" rid="ref16">17</xref>
                </sup> models the relationship between the covariates and the conditional expectiles of the outcome variable. The methodology is a generalization of the mean regression and closely related to quantile regression. It uses expectiles-points that minimize an asymmetric quadratic loss function 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>l</mml:mi>
                            <mml:mi>&#x03c4;</mml:mi>
                        </mml:msub>
                        <mml:mspace width="0.25em"/>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>t</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>=</mml:mo>
                        <mml:msup>
                            <mml:mi>t</mml:mi>
                            <mml:mn>2</mml:mn>
                        </mml:msup>
                        <mml:mo>.</mml:mo>
                        <mml:mo>|</mml:mo>
                        <mml:mi>&#x03c4;</mml:mi>
                        <mml:mo>&#x2212;</mml:mo>
                        <mml:mi>I</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>t</mml:mi>
                            <mml:mo>&lt;</mml:mo>
                            <mml:mn>0</mml:mn>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>|</mml:mo>
                    </mml:math>
</inline-formula>rather than the absolute loss function 

                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>l</mml:mi>
                            <mml:mi>&#x03b8;</mml:mi>
                        </mml:msub>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>t</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>=</mml:mo>
                        <mml:mi>t</mml:mi>
                        <mml:mo>.</mml:mo>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>&#x03b8;</mml:mi>
                            <mml:mo>&#x2212;</mml:mo>
                            <mml:mi>I</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>t</mml:mi>
                                <mml:mo>&lt;</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> used in quantile regression. Both the expectile level 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula> and the quantile level 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03b8;</mml:mi>
                    </mml:math>
</inline-formula> determine the degree of asymmetry of the loss function. Examining the asymmetric quadratic loss function reveals many of the properties that make expectile regression an attractive measure of risk.</p>
            <p>Compared to the mean value, expectiles are more sensitive to extreme values, and to the shape of the distribution in general. Furthermore, standard regression implicitly assumes normally distributed residuals, while such an assumption is not necessary in expectile regression. Expectile regression often leads to more efficient estimators compared to quantile regression, especially when the underlying error distribution is close to normal or when you&#x2019;re interested in extreme values of the conditional distribution. Estimation of expectile regression models can be done using iterative algorithms, such as weighted least squares or stochastic gradient descent, and reliable estimation approaches have been developed in both the classical and Bayesian literatures.</p>
            <p>Since its inception, expectile regression has attracted considerable interest in the literature. It has been applied in many different areas: finance and risk management,
                <sup>
                    <xref ref-type="bibr" rid="ref2">3</xref>,
                    <xref ref-type="bibr" rid="ref5">6</xref>,
                    <xref ref-type="bibr" rid="ref13">14</xref>
                </sup> actuarial science,
                <sup>
                    <xref ref-type="bibr" rid="ref3">4</xref>,
                    <xref ref-type="bibr" rid="ref6">7</xref>,
                    <xref ref-type="bibr" rid="ref15">16</xref>
                </sup> ecology and environmental studies,
                <sup>
                    <xref ref-type="bibr" rid="ref9">10</xref>,
                    <xref ref-type="bibr" rid="ref20">21</xref>,
                    <xref ref-type="bibr" rid="ref23">24</xref>
                </sup> social sciences,
                <sup>
                    <xref ref-type="bibr" rid="ref18">19</xref>,
                    <xref ref-type="bibr" rid="ref27">28</xref>
                </sup> and so on. In the recent decades, there exists considerable interest in the study of nonparametric and semiparametric models. Single-index model provides an efficient way of coping with high-dimensional nonparametric estimation problems and gives more flexibility and capture parameter heterogeneity and nonlinearity. Expectile regression with single-index models is an efficient method to model asymmetric relationships in data while achieving dimension reduction. There exists a large literature on classical methods for expectile regression with single-index models, and we refer to
                <sup>
                    <xref ref-type="bibr" rid="ref11">12</xref>,
                    <xref ref-type="bibr" rid="ref12">13</xref>
                </sup> for an overview. In contrast, a Bayesian method for estimating expectile regression with single index model has not been proposed, yet.</p>
            <p>In this paper, we consider a single-index expectile regression model. For a given expectile level 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mn>0</mml:mn>
                        <mml:mo>&lt;</mml:mo>
                        <mml:mi>&#x03c4;</mml:mi>
                        <mml:mo>&lt;</mml:mo>
                        <mml:mn>1</mml:mn>
                    </mml:math>
</inline-formula> and training data 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msubsup>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:mrow>
                                <mml:mi>i</mml:mi>
                                <mml:mo>=</mml:mo>
                                <mml:mn>1</mml:mn>
                            </mml:mrow>
                            <mml:mi>n</mml:mi>
                        </mml:msubsup>
                    </mml:math>
</inline-formula>, it is given by 
                <disp-formula id="e127">

                    <mml:math display="block">
                        <mml:msub>
                            <mml:mi>E</mml:mi>
                            <mml:mrow>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>|</mml:mo>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                            </mml:mrow>
                        </mml:msub>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>&#x03c4;</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>=</mml:mo>
                        <mml:mi>&#x03d5;</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:msubsup>
                                <mml:mi>x</mml:mi>
                                <mml:mi>i</mml:mi>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msubsup>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>,</mml:mo>
                        <mml:mspace width="0.25em"/>
                        <mml:mi>i</mml:mi>
                        <mml:mo>=</mml:mo>
                        <mml:mn>1</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mo>&#x2026;</mml:mo>
                        <mml:mo>,</mml:mo>
                        <mml:mi>n</mml:mi>
                        <mml:mo>.</mml:mo>
                    </mml:math>
</disp-formula>
            </p>
            <p>Here, 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>&#x0415;</mml:mi>
                            <mml:mrow>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>|</mml:mo>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                            </mml:mrow>
                        </mml:msub>
                        <mml:mo stretchy="true">(</mml:mo>
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula>) is the 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula>th expectile function of 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>y</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula> given 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>x</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula>, 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>x</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                        <mml:mspace width="0.25em"/>
                        <mml:mo>&#x2208;</mml:mo>
                        <mml:mspace width="0.25em"/>
                        <mml:msup>
                            <mml:mi>&#x211d;</mml:mi>
                            <mml:mi>p</mml:mi>
                        </mml:msup>
                    </mml:math>
</inline-formula> is the covariate vector for the 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>i</mml:mi>
                    </mml:math>
</inline-formula>-th observation, 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>y</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                        <mml:mspace width="0.25em"/>
                        <mml:mo>&#x2208;</mml:mo>
                        <mml:mspace width="0.25em"/>
                        <mml:mi>&#x211d;</mml:mi>
                    </mml:math>
</inline-formula> is the response corresponding to the covariate vector 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>x</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula>, 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03d5;</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mo>.</mml:mo>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> is the unknown univariate link function, and 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03b2;</mml:mi>
                        <mml:mo>=</mml:mo>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:msub>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mn>1</mml:mn>
                            </mml:msub>
                            <mml:mo>,</mml:mo>
                            <mml:msub>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msub>
                            <mml:mo>,</mml:mo>
                            <mml:mo>&#x22ef;</mml:mo>
                            <mml:mo>,</mml:mo>
                            <mml:msub>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mi>k</mml:mi>
                            </mml:msub>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> is the parametric index vector which implicitly depends on the desired expectile level 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                    </mml:math>
</inline-formula>. Following
                <sup>
                    <xref ref-type="bibr" rid="ref14">15</xref>
                </sup> and
                <sup>
                    <xref ref-type="bibr" rid="ref11">12</xref>
                </sup> for the sake of identifiability, we assume that 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mrow>
                            <mml:mo stretchy="true">&#x2016;</mml:mo>
                            <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                            <mml:mo stretchy="true">&#x2016;</mml:mo>
                        </mml:mrow>
                        <mml:mo>=</mml:mo>
                        <mml:mn>1</mml:mn>
                    </mml:math>
</inline-formula> and that the first component of 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03b2;</mml:mi>
                    </mml:math>
</inline-formula> is positive, 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mo>&#x2225;</mml:mo>
                        <mml:mo>&#x00b7;</mml:mo>
                        <mml:mo>&#x2225;</mml:mo>
                    </mml:math>
</inline-formula> refers to the Euclidean norm.</p>
            <p>The single index regression model is a form of dimension reduction in regression where the covariate vector 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>x</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula> is reduced to a one-dimensional index, so that 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03d5;</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:msubsup>
                                <mml:mi>x</mml:mi>
                                <mml:mi>i</mml:mi>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msubsup>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> is a univariate function instead of k-variate one, allowing for more interpretable and efficient modeling of the outcome of interest. In this paper, we establish a hierarchical Bayesian model by using asymmetric normal distribution (AND). As shown in 
                <xref ref-type="fig" rid="f1">
Figure 1</xref>, the asymmetric normal distribution exhibits different shapes depending on the expectile level 
                <italic toggle="yes">&#x03c4;</italic>. For detailed information on Bayesian expectile regression methods, see,
                <sup>
                    <xref ref-type="bibr" rid="ref24">25</xref>,
                    <xref ref-type="bibr" rid="ref22">23</xref>,
                    <xref ref-type="bibr" rid="ref25">26</xref>
                </sup> and.
                <sup>
                    <xref ref-type="bibr" rid="ref19">20</xref>
                </sup> Following
                <sup>
                    <xref ref-type="bibr" rid="ref10">11</xref>
                </sup> and,
                <sup>
                    <xref ref-type="bibr" rid="ref28">29</xref>
                </sup> we assign a Gaussian process prior distribution on 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03d5;</mml:mi>
                    </mml:math>
</inline-formula>, to get a flexible nonparametric expectile regression model.</p>
            <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                <label>
Figure 1. </label>
                <caption>
                    <title>Probability density functions of the AND with 
                        <inline-formula>

                            <mml:math display="inline">
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo>=</mml:mo>
                                <mml:mn>1</mml:mn>
                            </mml:math>
</inline-formula> and 
                        <inline-formula>

                            <mml:math display="inline">
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo>=</mml:mo>
                                <mml:mn>0.10</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0.25</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0.50</mml:mn>
                            </mml:math>
</inline-formula>.
                        <sup>
                            <xref ref-type="bibr" rid="ref30">30</xref>
                        </sup>
                    </title>
                </caption>
                <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/192635/e7ed66e4-18e7-433a-8d86-8788ec3aac96_figure1.gif"/>
            </fig>
            <p>This paper proceeds as follows. In 
                <xref ref-type="sec" rid="sec2">
Section 2</xref>, we introduce single-index expectile regression, the proposed Bayesian hierarchical model, and derive the corresponding MCMC samplers. Simulation studies are then presented in 
                <xref ref-type="sec" rid="sec6">Section 3</xref> followed by a real data example in 
                <xref ref-type="sec" rid="sec9">
Section 4</xref>. Conclusions is put in 
                <xref ref-type="sec" rid="sec10">
Section 5</xref>.</p>
        </sec>
        <sec id="sec2" sec-type="methods">
            <title>2. Methods</title>
            <sec id="sec3">
                <title>2.1 Single-Index expectile regression</title>
                <p>In the single-index expectile regression, the regression coefficients 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                        </mml:math>
</inline-formula> can be estimated through optimizing the following empirical loss function
                    <disp-formula id="e2">

                        <mml:math display="block">
                            <mml:munder>
                                <mml:mo>min</mml:mo>
                                <mml:mi>&#x03b2;</mml:mi>
                            </mml:munder>
                            <mml:munderover>
                                <mml:mo>&#x2211;</mml:mo>
                                <mml:mrow>
                                    <mml:mi>i</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                                <mml:mi>n</mml:mi>
                            </mml:munderover>
                            <mml:msub>
                                <mml:mi mathvariant="normal">&#x0196;</mml:mi>
                                <mml:mi>&#x03c4;</mml:mi>
                            </mml:msub>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msubsup>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                        <mml:mo>&#x2032;</mml:mo>
                                    </mml:msubsup>
                                    <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(2)</label>
</disp-formula>where the loss function
                    <disp-formula id="e3">

                        <mml:math display="block">
                            <mml:msub>
                                <mml:mi mathvariant="normal">&#x0196;</mml:mi>
                                <mml:mi>&#x03c4;</mml:mi>
                            </mml:msub>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msubsup>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                        <mml:mo>&#x2032;</mml:mo>
                                    </mml:msubsup>
                                    <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>y</mml:mi>
                                        <mml:mi>i</mml:mi>
                                    </mml:msub>
                                    <mml:mo>-</mml:mo>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                            <mml:mrow>
                                <mml:mo>|</mml:mo>
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>I</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>y</mml:mi>
                                        <mml:mi>i</mml:mi>
                                    </mml:msub>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo>&lt;</mml:mo>
                                    <mml:mn>0</mml:mn>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>|</mml:mo>
                            </mml:mrow>
                            <mml:mo>.</mml:mo>
                        </mml:math>

                        <label>(3)</label>
</disp-formula>
                </p>
                <p>Equivalently, we may write (3) as
                    <disp-formula id="e4">

                        <mml:math display="block">
                            <mml:mspace width="0.25em"/>
                            <mml:msub>
                                <mml:mi>&#x0196;</mml:mi>
                                <mml:mi>&#x03c4;</mml:mi>
                            </mml:msub>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msubsup>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                        <mml:mo>&#x2032;</mml:mo>
                                    </mml:msubsup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mtable displaystyle="true">
                                    <mml:mtr>
                                        <mml:mtd columnalign="left">
                                            <mml:mi>&#x03c4;</mml:mi>
                                            <mml:msup>
                                                <mml:mrow>
                                                    <mml:mo stretchy="true">(</mml:mo>
                                                    <mml:msub>
                                                        <mml:mi>y</mml:mi>
                                                        <mml:mi>i</mml:mi>
                                                    </mml:msub>
                                                    <mml:mo>&#x2212;</mml:mo>
                                                    <mml:mi>&#x03d5;</mml:mi>
                                                    <mml:mrow>
                                                        <mml:mo stretchy="true">(</mml:mo>
                                                        <mml:msubsup>
                                                            <mml:mi>x</mml:mi>
                                                            <mml:mi>i</mml:mi>
                                                            <mml:mo>&#x2032;</mml:mo>
                                                        </mml:msubsup>
                                                        <mml:mi>&#x03b2;</mml:mi>
                                                        <mml:mo stretchy="true">)</mml:mo>
                                                    </mml:mrow>
                                                    <mml:mo stretchy="true">)</mml:mo>
                                                </mml:mrow>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>,</mml:mo>
                                        </mml:mtd>
                                        <mml:mtd columnalign="left">
                                            <mml:mtext mathvariant="italic">if</mml:mtext>
                                            <mml:mspace width="0.25em"/>
                                            <mml:msub>
                                                <mml:mi>y</mml:mi>
                                                <mml:mi>i</mml:mi>
                                            </mml:msub>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mi>&#x03d5;</mml:mi>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:msubsup>
                                                    <mml:mi>x</mml:mi>
                                                    <mml:mi>i</mml:mi>
                                                    <mml:mo>&#x2032;</mml:mo>
                                                </mml:msubsup>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mspace width="0.25em"/>
                                            <mml:mo>&#x2265;</mml:mo>
                                            <mml:mspace width="0.25em"/>
                                            <mml:mn>0</mml:mn>
                                            <mml:mo>,</mml:mo>
                                        </mml:mtd>
                                    </mml:mtr>
                                    <mml:mtr>
                                        <mml:mtd columnalign="left">
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mn>1</mml:mn>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mi>&#x03c4;</mml:mi>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:msup>
                                                <mml:mrow>
                                                    <mml:mo stretchy="true">(</mml:mo>
                                                    <mml:msub>
                                                        <mml:mi>y</mml:mi>
                                                        <mml:mi>i</mml:mi>
                                                    </mml:msub>
                                                    <mml:mo>&#x2212;</mml:mo>
                                                    <mml:mi>&#x03d5;</mml:mi>
                                                    <mml:mrow>
                                                        <mml:mo stretchy="true">(</mml:mo>
                                                        <mml:msubsup>
                                                            <mml:mi>x</mml:mi>
                                                            <mml:mi>i</mml:mi>
                                                            <mml:mo>&#x2032;</mml:mo>
                                                        </mml:msubsup>
                                                        <mml:mi>&#x03b2;</mml:mi>
                                                        <mml:mo stretchy="true">)</mml:mo>
                                                    </mml:mrow>
                                                    <mml:mo stretchy="true">)</mml:mo>
                                                </mml:mrow>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>,</mml:mo>
                                        </mml:mtd>
                                        <mml:mtd>
                                            <mml:mtext mathvariant="italic">if</mml:mtext>
                                            <mml:mspace width="0.25em"/>
                                            <mml:msub>
                                                <mml:mi>y</mml:mi>
                                                <mml:mi>i</mml:mi>
                                            </mml:msub>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mi>&#x03d5;</mml:mi>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:msubsup>
                                                    <mml:mi>x</mml:mi>
                                                    <mml:mi>i</mml:mi>
                                                    <mml:mo>&#x2032;</mml:mo>
                                                </mml:msubsup>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mo>&lt;</mml:mo>
                                            <mml:mn>0</mml:mn>
                                            <mml:mo>.</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                            <mml:mo>&#x00a0;</mml:mo>
                                        </mml:mtd>
                                    </mml:mtr>
                                </mml:mtable>
                            </mml:mrow>
                        </mml:math>
</disp-formula>
                </p>
                <p>Rather than minimizing the usual expectile loss function (2), we solve the minimization problem by constructing a Markov chain having the joint posterior for the expectile regression coefficients 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                        </mml:math>
</inline-formula> as its stationary distribution with the minimizer of (2) as its global mode. The quadratic asymmetric loss function (2) is exactly equivalent to the AND; see
                    <sup>
                        <xref ref-type="bibr" rid="ref22">23</xref>,
                        <xref ref-type="bibr" rid="ref24">25</xref>
                    </sup> and.
                    <sup>
                        <xref ref-type="bibr" rid="ref19">20</xref>
                    </sup> The density function of an AND
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>&#x03bc;</mml:mi>
                                <mml:mo>,</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo>,</mml:mo>
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula> is
                    <disp-formula id="e5">

                        <mml:math display="block">
                            <mml:mi>p</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mfrac>
                                <mml:mn>2</mml:mn>
                                <mml:msqrt>
                                    <mml:msup>
                                        <mml:mi>&#x03c3;</mml:mi>
                                        <mml:mn>2</mml:mn>
                                    </mml:msup>
                                    <mml:mi>&#x03c0;</mml:mi>
                                </mml:msqrt>
                            </mml:mfrac>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mfrac>
                                    <mml:msqrt>
                                        <mml:mi>&#x03c4;</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mn>1</mml:mn>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mi>&#x03c4;</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:msqrt>
                                    <mml:mrow>
                                        <mml:msqrt>
                                            <mml:mi>&#x03c4;</mml:mi>
                                        </mml:msqrt>
                                        <mml:mo>+</mml:mo>
                                        <mml:msqrt>
                                            <mml:mn>1</mml:mn>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mi>&#x03c4;</mml:mi>
                                        </mml:msqrt>
                                    </mml:mrow>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:msub>
                                            <mml:mi>v</mml:mi>
                                            <mml:mi>i</mml:mi>
                                        </mml:msub>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>y</mml:mi>
                                                    <mml:mi>i</mml:mi>
                                                </mml:msub>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mi>&#x03d5;</mml:mi>
                                                <mml:mrow>
                                                    <mml:mo stretchy="true">(</mml:mo>
                                                    <mml:msubsup>
                                                        <mml:mi>x</mml:mi>
                                                        <mml:mi>i</mml:mi>
                                                        <mml:mo>&#x2032;</mml:mo>
                                                    </mml:msubsup>
                                                    <mml:mi>&#x03b2;</mml:mi>
                                                    <mml:mo stretchy="true">)</mml:mo>
                                                </mml:mrow>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:mrow>
                                    <mml:mrow>
                                        <mml:mn>2</mml:mn>
                                        <mml:msup>
                                            <mml:mi>&#x03c3;</mml:mi>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:mrow>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(4)</label>
</disp-formula>where, 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03c4;</mml:mi>
                        </mml:math>
</inline-formula> is the skew parameter, 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                        </mml:math>
</inline-formula> is the scale parameter, 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>&#x03bc;</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>=</mml:mo>
                            <mml:mi>&#x03d5;</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msubsup>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msubsup>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula> is the location parameter and 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>v</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo>|</mml:mo>
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>I</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>y</mml:mi>
                                        <mml:mi>i</mml:mi>
                                    </mml:msub>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi mathvariant="bold-italic">&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo>&lt;</mml:mo>
                                    <mml:mn>0</mml:mn>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>|</mml:mo>
                            </mml:mrow>
                            <mml:mo>.</mml:mo>
                        </mml:math>
</inline-formula>Minimizing (2) is equivalent to maximizing the likelihood function of 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>y</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                        </mml:math>
</inline-formula> by assuming 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>y</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                        </mml:math>
</inline-formula> from an AND with 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>&#x03bc;</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>=</mml:mo>
                            <mml:mi>&#x03d5;</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msubsup>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msubsup>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>.</p>
            </sec>
            <sec id="sec4">
                <title>2.2 Bayesian hierarchical model</title>
                <p>Following
                    <sup>
                        <xref ref-type="bibr" rid="ref10">11</xref>,
                        <xref ref-type="bibr" rid="ref28">29</xref>,
                        <xref ref-type="bibr" rid="ref4">5</xref>
                    </sup> and,
                    <sup>
                        <xref ref-type="bibr" rid="ref7">8</xref>
                    </sup> we model the nonparametric link function 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03d5;</mml:mi>
                        </mml:math>
</inline-formula> by a Gaussian process (GP) prior with mean zero and covariance function 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>C</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mo>&#x00b7;</mml:mo>
                                <mml:mo>,</mml:mo>
                                <mml:mo>&#x00b7;</mml:mo>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>, i.e. 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03d5;</mml:mi>
                            <mml:mo>~</mml:mo>
                            <mml:mi mathvariant="italic">GP</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn mathvariant="bold">0</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mi>C</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mo>&#x00b7;</mml:mo>
                                    <mml:mo>,</mml:mo>
                                    <mml:mo>&#x00b7;</mml:mo>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>, where
                    <disp-formula id="e6">

                        <mml:math display="block">
                            <mml:mi mathvariant="normal">C</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mi>r</mml:mi>
                            <mml:mspace width="0.25em"/>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>x</mml:mi>
                                                    <mml:mi>i</mml:mi>
                                                </mml:msub>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>x</mml:mi>
                                                    <mml:mi>j</mml:mi>
                                                </mml:msub>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msup>
                                        <mml:mi>&#x03b2;</mml:mi>
                                        <mml:msup>
                                            <mml:mi>&#x03b2;</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msup>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:msub>
                                                <mml:mi>x</mml:mi>
                                                <mml:mi>i</mml:mi>
                                            </mml:msub>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:msub>
                                                <mml:mi>x</mml:mi>
                                                <mml:mi>j</mml:mi>
                                            </mml:msub>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:mrow>
                                    <mml:mi>b</mml:mi>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(5)</label>
</disp-formula>
                </p>
                <p>Here, 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>r</mml:mi>
                        </mml:math>
</inline-formula> and 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>b</mml:mi>
                        </mml:math>
</inline-formula> are two hyperparameters. Following
                    <sup>
                        <xref ref-type="bibr" rid="ref10">11</xref>
                    </sup> and,
                    <sup>
                        <xref ref-type="bibr" rid="ref28">29</xref>
                    </sup> we replace 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>/</mml:mo>
                            <mml:msqrt>
                                <mml:mi>b</mml:mi>
                            </mml:msqrt>
                        </mml:math>
</inline-formula> with a new index vector, still denoted by 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                        </mml:math>
</inline-formula>, to simplify the estimation procedure. Thus, the Gaussian process (GP) prior in (5) can be written as
                    <disp-formula id="e7">

                        <mml:math display="block">
                            <mml:mi>C</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:msub>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mi>r</mml:mi>
                            <mml:mspace width="0.25em"/>
                            <mml:mo mathvariant="italic">exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:msup>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msub>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                        </mml:msub>
                                        <mml:mo>&#x2212;</mml:mo>
                                        <mml:msub>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>j</mml:mi>
                                        </mml:msub>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:msup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                    </mml:msub>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:msub>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>j</mml:mi>
                                    </mml:msub>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>.</mml:mo>
                        </mml:math>

                        <label>(6)</label>
</disp-formula>
                </p>
                <p>To proceed a Bayesian analysis, we assign a Laplace prior for 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mi>j</mml:mi>
                            </mml:msub>
                            <mml:mo>,</mml:mo>
                            <mml:mi>j</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mn>1</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mo>&#x22ef;</mml:mo>
                            <mml:mo>,</mml:mo>
                            <mml:mi>p</mml:mi>
                            <mml:mo>,</mml:mo>
                        </mml:math>
</inline-formula> of the form
                    <sup>
                        <xref ref-type="bibr" rid="ref1">2</xref>,
                        <xref ref-type="bibr" rid="ref21">22</xref>
                    </sup>
                    <disp-formula id="e8">

                        <mml:math display="block">
                            <mml:mi>f</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo>|</mml:mo>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:munderover>
                                <mml:mo>&#x220f;</mml:mo>
                                <mml:mrow>
                                    <mml:mi>j</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                                <mml:mi>k</mml:mi>
                            </mml:munderover>
                            <mml:mfrac>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mrow>
                                    <mml:mn>2</mml:mn>
                                    <mml:mi>&#x03c3;</mml:mi>
                                </mml:mrow>
                            </mml:mfrac>
                            <mml:mo mathvariant="italic">exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:msub>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mi>i</mml:mi>
                                        </mml:msub>
                                        <mml:mrow>
                                            <mml:mo>|</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mi>j</mml:mi>
                                            </mml:msub>
                                            <mml:mo>|</mml:mo>
                                        </mml:mrow>
                                    </mml:mrow>
                                    <mml:mi>&#x03c3;</mml:mi>
                                </mml:mfrac>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(7)</label>
</disp-formula>which extends Bayesian Lasso
                    <sup>
                        <xref ref-type="bibr" rid="ref17">18</xref>
                    </sup> by allowing different penalization parameters 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo>&gt;</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula> for different regression coefficients. We further put a Gamma prior on the parameter 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>&#x03bb;</mml:mi>
                                <mml:mi>j</mml:mi>
                            </mml:msub>
                        </mml:math>
</inline-formula> of the form 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>p</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mspace width="0.25em"/>
                            <mml:mo>&#x221d;</mml:mo>
                            <mml:mspace width="0.25em"/>
                            <mml:msubsup>
                                <mml:mi>&#x03bb;</mml:mi>
                                <mml:mi>j</mml:mi>
                                <mml:mrow>
                                    <mml:mi>a</mml:mi>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                            </mml:msubsup>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>b</mml:mi>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                            <mml:mi>p</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mn>1</mml:mn>
                            <mml:mo>/</mml:mo>
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                        </mml:math>
</inline-formula>on 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                        </mml:math>
</inline-formula> and inverse Gamma prior on 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>r</mml:mi>
                            <mml:mo>,</mml:mo>
                            <mml:mi>i</mml:mi>
                            <mml:mo>.</mml:mo>
                            <mml:mi>e</mml:mi>
                            <mml:mo>.</mml:mo>
                            <mml:mi>r</mml:mi>
                            <mml:mo>&#x223c;</mml:mo>
                            <mml:mi mathvariant="italic">IG</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>c</mml:mi>
                                <mml:mo>,</mml:mo>
                                <mml:mi>d</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>, where 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>c</mml:mi>
                        </mml:math>
</inline-formula> and 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>d</mml:mi>
                        </mml:math>
</inline-formula> are two hyperparameters. Thus, a fully bayesian approach for expectile adaptive lasso regression with single index model can be described as follows:
                    <disp-formula id="e9">

                        <mml:math display="block">
                            <mml:msub>
                                <mml:mi>y</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>|</mml:mo>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>,</mml:mo>
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                            <mml:mo>~</mml:mo>
                            <mml:mtext mathvariant="italic">AND</mml:mtext>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msubsup>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                        <mml:mo>&#x2032;</mml:mo>
                                    </mml:msubsup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>,</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo>,</mml:mo>
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(8)</label>
</disp-formula>

                    <disp-formula id="e10">

                        <mml:math display="block">
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>|</mml:mo>
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                            <mml:mo>,</mml:mo>
                            <mml:mstyle displaystyle="false">
                                <mml:mi>&#x03bb;</mml:mi>
                            </mml:mstyle>
                            <mml:mo>&#x223c;</mml:mo>
                            <mml:munderover>
                                <mml:mo>&#x220f;</mml:mo>
                                <mml:mrow>
                                    <mml:mi>j</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                                <mml:mi>k</mml:mi>
                            </mml:munderover>
                            <mml:mfrac>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mrow>
                                    <mml:mn>2</mml:mn>
                                    <mml:mi>&#x03c3;</mml:mi>
                                </mml:mrow>
                            </mml:mfrac>
                            <mml:mo mathvariant="italic">exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:msub>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mi>j</mml:mi>
                                        </mml:msub>
                                        <mml:mrow>
                                            <mml:mo>|</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mi>j</mml:mi>
                                            </mml:msub>
                                            <mml:mo>|</mml:mo>
                                        </mml:mrow>
                                    </mml:mrow>
                                    <mml:mi>&#x03c3;</mml:mi>
                                </mml:mfrac>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(9)</label>
</disp-formula>

                    <disp-formula id="e11">

                        <mml:math display="block">
                            <mml:msub>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mi>n</mml:mi>
                            </mml:msub>
                            <mml:mo>|</mml:mo>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>,</mml:mo>
                            <mml:mi>r</mml:mi>
                            <mml:mo>~</mml:mo>
                            <mml:mi mathvariant="italic">GP</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>C</mml:mi>
                                    <mml:mi>n</mml:mi>
                                </mml:msub>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mo>.</mml:mo>
                                    <mml:mo>,</mml:mo>
                                    <mml:mo>.</mml:mo>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(10)</label>
</disp-formula>

                    <disp-formula id="e12">

                        <mml:math display="block">
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                            <mml:mo>~</mml:mo>
                            <mml:mn>1</mml:mn>
                            <mml:mo>/</mml:mo>
                            <mml:msup>
                                <mml:mi>&#x03c3;</mml:mi>
                                <mml:mn>2</mml:mn>
                            </mml:msup>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(11)</label>
</disp-formula>

                    <disp-formula id="e13">

                        <mml:math display="block">
                            <mml:msub>
                                <mml:mi>&#x03bb;</mml:mi>
                                <mml:mi>j</mml:mi>
                            </mml:msub>
                            <mml:mo>~</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>&#x03bb;</mml:mi>
                                        <mml:mi>j</mml:mi>
                                    </mml:msub>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mrow>
                                    <mml:mi>a</mml:mi>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                            </mml:msup>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>b</mml:mi>
                                <mml:msub>
                                    <mml:mi>&#x03bb;</mml:mi>
                                    <mml:mi>j</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                        </mml:math>

                        <label>(12)</label>
</disp-formula>

                    <disp-formula id="e14">

                        <mml:math display="block">
                            <mml:mi>r</mml:mi>
                            <mml:mo>~</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mfrac>
                                        <mml:mn>1</mml:mn>
                                        <mml:mi>r</mml:mi>
                                    </mml:mfrac>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mrow>
                                    <mml:mi>c</mml:mi>
                                    <mml:mo>+</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                            </mml:msup>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mfrac>
                                    <mml:mi>d</mml:mi>
                                    <mml:mi>r</mml:mi>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>

                        <label>(13)</label>
</disp-formula>where 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03bb;</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>&#x03bb;</mml:mi>
                                        <mml:mn>1</mml:mn>
                                    </mml:msub>
                                    <mml:mo>,</mml:mo>
                                    <mml:mo>&#x2026;</mml:mo>
                                    <mml:mo>,</mml:mo>
                                    <mml:msub>
                                        <mml:mi>&#x03bb;</mml:mi>
                                        <mml:mi>k</mml:mi>
                                    </mml:msub>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msup>
                            <mml:mo>,</mml:mo>
                            <mml:msub>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mi>n</mml:mi>
                            </mml:msub>
                            <mml:mo>=</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msub>
                                        <mml:mi>&#x03d5;</mml:mi>
                                        <mml:mn>1</mml:mn>
                                    </mml:msub>
                                    <mml:mo>,</mml:mo>
                                    <mml:mo>&#x2026;</mml:mo>
                                    <mml:mo>,</mml:mo>
                                    <mml:msub>
                                        <mml:mi>&#x03d5;</mml:mi>
                                        <mml:mi>n</mml:mi>
                                    </mml:msub>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msup>
                            <mml:mo>=</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi>&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo>,</mml:mo>
                                    <mml:mo>&#x2026;</mml:mo>
                                    <mml:mo>,</mml:mo>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi>&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msup>
                            <mml:mo>.</mml:mo>
                        </mml:math>
</inline-formula>
                </p>
            </sec>
            <sec id="sec5">
                <title>2.3 MCMC sampling</title>
                <p>The posterior distribution of all parameters of interest is found via MCMC sampling algorithm and the details of full conditional distributions are given below.
                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>Sample the regression coefficients 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mi>&#x03b2;</mml:mi>
                                    </mml:math>
</inline-formula> from their posteriors using a random walk Metropolis-Hastings steps,</p>
                        </list-item>
                    </list>

                    <disp-formula id="e15">

                        <mml:math display="block">
                            <mml:mtable displaystyle="true">
                                <mml:mtr>
                                    <mml:mtd>
                                        <mml:mi>f</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>&#x03b2;</mml:mi>
                                            <mml:mo>|</mml:mo>
                                            <mml:msup>
                                                <mml:mi>&#x03c3;</mml:mi>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>,</mml:mo>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mo>,</mml:mo>
                                            <mml:mi>r</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mo>&#x221d;</mml:mo>
                                        <mml:mo>&#x222b;</mml:mo>
                                        <mml:mi>f</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>y</mml:mi>
                                            <mml:mo>|</mml:mo>
                                            <mml:msup>
                                                <mml:mi>&#x03c3;</mml:mi>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>,</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03d5;</mml:mi>
                                                <mml:mi>n</mml:mi>
                                            </mml:msub>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mi>f</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03d5;</mml:mi>
                                                <mml:mi>n</mml:mi>
                                            </mml:msub>
                                            <mml:mo>|</mml:mo>
                                            <mml:mi>&#x03b2;</mml:mi>
                                            <mml:mo>,</mml:mo>
                                            <mml:mi>r</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mi>d</mml:mi>
                                        <mml:msub>
                                            <mml:mi>&#x03d5;</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:mi>f</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>&#x03b2;</mml:mi>
                                            <mml:mo>|</mml:mo>
                                            <mml:msup>
                                                <mml:mi>&#x03c3;</mml:mi>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>,</mml:mo>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:mtd>
                                </mml:mtr>
                                <mml:mtr>
                                    <mml:mtd>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x00a0;</mml:mo>
                                        <mml:mo>&#x221d;</mml:mo>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mo>det</mml:mo>
                                                <mml:mrow>
                                                    <mml:mo stretchy="true">[</mml:mo>
                                                    <mml:mi>V</mml:mi>
                                                    <mml:mo>+</mml:mo>
                                                    <mml:msub>
                                                        <mml:mi>C</mml:mi>
                                                        <mml:mi>n</mml:mi>
                                                    </mml:msub>
                                                    <mml:mo stretchy="true">]</mml:mo>
                                                </mml:mrow>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mrow>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mfrac>
                                                    <mml:mn>1</mml:mn>
                                                    <mml:mn>2</mml:mn>
                                                </mml:mfrac>
                                            </mml:mrow>
                                        </mml:msup>
                                        <mml:mo mathvariant="italic">exp</mml:mo>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">{</mml:mo>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mfrac>
                                                <mml:mrow>
                                                    <mml:msup>
                                                        <mml:mi>y</mml:mi>
                                                        <mml:mo>&#x2032;</mml:mo>
                                                    </mml:msup>
                                                    <mml:mrow>
                                                        <mml:mo stretchy="true">(</mml:mo>
                                                        <mml:mi>V</mml:mi>
                                                        <mml:mo>+</mml:mo>
                                                        <mml:msub>
                                                            <mml:mi>C</mml:mi>
                                                            <mml:mi>n</mml:mi>
                                                        </mml:msub>
                                                        <mml:mo stretchy="true">)</mml:mo>
                                                    </mml:mrow>
                                                    <mml:mi>y</mml:mi>
                                                </mml:mrow>
                                                <mml:mrow>
                                                    <mml:mn>2</mml:mn>
                                                    <mml:msup>
                                                        <mml:mi>&#x03c3;</mml:mi>
                                                        <mml:mn>2</mml:mn>
                                                    </mml:msup>
                                                </mml:mrow>
                                            </mml:mfrac>
                                            <mml:mo stretchy="true">}</mml:mo>
                                        </mml:mrow>
                                        <mml:munderover>
                                            <mml:mo>&#x220f;</mml:mo>
                                            <mml:mrow>
                                                <mml:mi>j</mml:mi>
                                                <mml:mo>=</mml:mo>
                                                <mml:mn>1</mml:mn>
                                            </mml:mrow>
                                            <mml:mi>k</mml:mi>
                                        </mml:munderover>
                                        <mml:mo mathvariant="italic">exp</mml:mo>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">{</mml:mo>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mfrac>
                                                <mml:mrow>
                                                    <mml:msub>
                                                        <mml:mi>&#x03bb;</mml:mi>
                                                        <mml:mi>j</mml:mi>
                                                    </mml:msub>
                                                    <mml:mrow>
                                                        <mml:mo>|</mml:mo>
                                                        <mml:msub>
                                                            <mml:mi>&#x03b2;</mml:mi>
                                                            <mml:mi>j</mml:mi>
                                                        </mml:msub>
                                                        <mml:mo>|</mml:mo>
                                                    </mml:mrow>
                                                </mml:mrow>
                                                <mml:msup>
                                                    <mml:mi>&#x03c3;</mml:mi>
                                                    <mml:mn>2</mml:mn>
                                                </mml:msup>
                                            </mml:mfrac>
                                            <mml:mo stretchy="true">}</mml:mo>
                                        </mml:mrow>
                                        <mml:mo>,</mml:mo>
                                    </mml:mtd>
                                </mml:mtr>
                            </mml:mtable>
                        </mml:math>

                        <label>(14)</label>
</disp-formula>where the weight matrix 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>V</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mo mathvariant="italic">diag</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>v</mml:mi>
                                    <mml:mn>1</mml:mn>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:mo>&#x2026;</mml:mo>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>v</mml:mi>
                                    <mml:mi>n</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula> adjusts for the expectile loss so that 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:msub>
                                <mml:mi>v</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo>|</mml:mo>
                                <mml:mi>&#x03c4;</mml:mi>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>I</mml:mi>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>y</mml:mi>
                                    <mml:mi>i</mml:mi>
                                </mml:msub>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:msubsup>
                                        <mml:mi>x</mml:mi>
                                        <mml:mi>i</mml:mi>
                                        <mml:mo>&#x2032;</mml:mo>
                                    </mml:msubsup>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mo>&lt;</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo>|</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>.
                    <list list-type="order">
                        <list-item>
                            <label>2.</label>
                            <p>Sample the hyperparameter 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mi>r</mml:mi>
                                    </mml:math>
</inline-formula> from the posterior using a random walk Metropolis-Hastings steps,</p>
                        </list-item>
                    </list>

                    <disp-formula id="e17">

                        <mml:math display="block">
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mi>f</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>r</mml:mi>
                                <mml:mo>|</mml:mo>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mo>,</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo>,</mml:mo>
                                <mml:mi>&#x03bb;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>&#x221d;</mml:mo>
                            <mml:mo>&#x222b;</mml:mo>
                            <mml:mi>f</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>y</mml:mi>
                                <mml:mo>|</mml:mo>
                                <mml:msup>
                                    <mml:mi>&#x03c3;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mi>n</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mi>f</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03d5;</mml:mi>
                                    <mml:mi>n</mml:mi>
                                </mml:msub>
                                <mml:mrow>
                                    <mml:mo>|</mml:mo>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mo>,</mml:mo>
                                    <mml:mi>r</mml:mi>
                                    <mml:mo>&#x00a0;</mml:mo>
                                </mml:mrow>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mi>d</mml:mi>
                            <mml:msub>
                                <mml:mi>&#x03d5;</mml:mi>
                                <mml:mi>n</mml:mi>
                            </mml:msub>
                            <mml:mi>f</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>r</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mspace width="0.25em"/>
                            <mml:mspace linebreak="newline"/>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x00a0;</mml:mo>
                            <mml:mo>&#x221d;</mml:mo>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mo>det</mml:mo>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">[</mml:mo>
                                        <mml:mi>V</mml:mi>
                                        <mml:mo>+</mml:mo>
                                        <mml:msub>
                                            <mml:mi>C</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:mo stretchy="true">]</mml:mo>
                                    </mml:mrow>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mrow>
                                    <mml:mo>&#x2212;</mml:mo>
                                    <mml:mfrac>
                                        <mml:mn>1</mml:mn>
                                        <mml:mn>2</mml:mn>
                                    </mml:mfrac>
                                </mml:mrow>
                            </mml:msup>
                            <mml:mo mathvariant="italic">exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:msup>
                                            <mml:mi>y</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msup>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>V</mml:mi>
                                            <mml:mo>+</mml:mo>
                                            <mml:msub>
                                                <mml:mi>C</mml:mi>
                                                <mml:mi>n</mml:mi>
                                            </mml:msub>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mi>y</mml:mi>
                                    </mml:mrow>
                                    <mml:mrow>
                                        <mml:mn>2</mml:mn>
                                        <mml:msup>
                                            <mml:mi>&#x03c3;</mml:mi>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:mrow>
                                </mml:mfrac>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                            <mml:msup>
                                <mml:mrow>
                                    <mml:mo stretchy="true">(</mml:mo>
                                    <mml:mfrac>
                                        <mml:mn>1</mml:mn>
                                        <mml:mi>r</mml:mi>
                                    </mml:mfrac>
                                    <mml:mo stretchy="true">)</mml:mo>
                                </mml:mrow>
                                <mml:mrow>
                                    <mml:mi>c</mml:mi>
                                    <mml:mo>+</mml:mo>
                                    <mml:mn>1</mml:mn>
                                </mml:mrow>
                            </mml:msup>
                            <mml:mo>exp</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mfrac>
                                    <mml:mi>d</mml:mi>
                                    <mml:mi>r</mml:mi>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>

                        <label>(15)</label>
</disp-formula>

                    <list list-type="order">
                        <list-item>
                            <label>3.</label>
                            <p>Sample the nonparametric link function 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msub>
                                            <mml:mi>&#x03d5;</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                    </mml:math>
</inline-formula> from a multivariate normal distribution with mean 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msub>
                                            <mml:mi>&#x03bc;</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:mo>=</mml:mo>
                                        <mml:msub>
                                            <mml:mi>C</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mi>V</mml:mi>
                                                <mml:mo>+</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>C</mml:mi>
                                                    <mml:mi>n</mml:mi>
                                                </mml:msub>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mrow>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mn>1</mml:mn>
                                            </mml:mrow>
                                        </mml:msup>
                                        <mml:mi>y</mml:mi>
                                    </mml:math>
</inline-formula> and variance 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msub>
                                            <mml:mi>&#x03a3;</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:mo>=</mml:mo>
                                        <mml:msub>
                                            <mml:mi>C</mml:mi>
                                            <mml:mi>n</mml:mi>
                                        </mml:msub>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mi>V</mml:mi>
                                                <mml:mo>+</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>C</mml:mi>
                                                    <mml:mi>n</mml:mi>
                                                </mml:msub>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mrow>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mn>1</mml:mn>
                                            </mml:mrow>
                                        </mml:msup>
                                        <mml:mi>V</mml:mi>
                                    </mml:math>
</inline-formula>
                            </p>
                        </list-item>
                        <list-item>
                            <label>4.</label>
                            <p>Sample 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msup>
                                            <mml:mi>&#x03c3;</mml:mi>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:math>
</inline-formula>from inverse Gamma (IG) with shape parameter 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>n</mml:mi>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mn>1</mml:mn>
                                            <mml:mo>+</mml:mo>
                                            <mml:mi>k</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mo>/</mml:mo>
                                        <mml:mn>2</mml:mn>
                                    </mml:math>
</inline-formula> and scale parameter 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:msubsup>
                                                <mml:mo>&#x2211;</mml:mo>
                                                <mml:mrow>
                                                    <mml:mi>i</mml:mi>
                                                    <mml:mo>=</mml:mo>
                                                    <mml:mn>1</mml:mn>
                                                </mml:mrow>
                                                <mml:mi>n</mml:mi>
                                            </mml:msubsup>
                                            <mml:msub>
                                                <mml:mi>v</mml:mi>
                                                <mml:mi>i</mml:mi>
                                            </mml:msub>
                                            <mml:msup>
                                                <mml:mrow>
                                                    <mml:mo stretchy="true">(</mml:mo>
                                                    <mml:msub>
                                                        <mml:mi>y</mml:mi>
                                                        <mml:mi>i</mml:mi>
                                                    </mml:msub>
                                                    <mml:mo>&#x2212;</mml:mo>
                                                    <mml:mi>&#x03d5;</mml:mi>
                                                    <mml:mrow>
                                                        <mml:mo stretchy="true">(</mml:mo>
                                                        <mml:msubsup>
                                                            <mml:mi>x</mml:mi>
                                                            <mml:mi>i</mml:mi>
                                                            <mml:mo>&#x2032;</mml:mo>
                                                        </mml:msubsup>
                                                        <mml:mi>&#x03b2;</mml:mi>
                                                        <mml:mo stretchy="true">)</mml:mo>
                                                    </mml:mrow>
                                                    <mml:mo stretchy="true">)</mml:mo>
                                                </mml:mrow>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>/</mml:mo>
                                            <mml:mn>2</mml:mn>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                        <mml:mo>+</mml:mo>
                                        <mml:msubsup>
                                            <mml:mo>&#x2211;</mml:mo>
                                            <mml:mrow>
                                                <mml:mi>j</mml:mi>
                                                <mml:mo>=</mml:mo>
                                                <mml:mn>1</mml:mn>
                                            </mml:mrow>
                                            <mml:mi>k</mml:mi>
                                        </mml:msubsup>
                                        <mml:msub>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mi>j</mml:mi>
                                        </mml:msub>
                                        <mml:mrow>
                                            <mml:mo>|</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mi>j</mml:mi>
                                            </mml:msub>
                                            <mml:mo>|</mml:mo>
                                        </mml:mrow>
                                    </mml:math>
</inline-formula>
                            </p>
                        </list-item>
                        <list-item>
                            <label>5.</label>
                            <p>Sample 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msub>
                                            <mml:mi>&#x03bb;</mml:mi>
                                            <mml:mi>j</mml:mi>
                                        </mml:msub>
                                    </mml:math>
</inline-formula>from Gamma distribution with shape parameter 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mi>a</mml:mi>
                                        <mml:mo>+</mml:mo>
                                        <mml:mn>1</mml:mn>
                                    </mml:math>
</inline-formula>and scale parameter 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mi>b</mml:mi>
                                        <mml:mo>+</mml:mo>
                                        <mml:mrow>
                                            <mml:mo>|</mml:mo>
                                            <mml:msub>
                                                <mml:mi>&#x03b2;</mml:mi>
                                                <mml:mi>j</mml:mi>
                                            </mml:msub>
                                            <mml:mo>|</mml:mo>
                                        </mml:mrow>
                                        <mml:mo>/</mml:mo>
                                        <mml:msup>
                                            <mml:mi>&#x03c3;</mml:mi>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:math>
</inline-formula>
                            </p>
                        </list-item>
                    </list>
                </p>
            </sec>
        </sec>
        <sec id="sec6">
            <title>3. Simulation studies</title>
            <p>In this section, we investigate the prediction accuracy of the proposed approach (BESIM) and compare its performance with a non-Bayesian single-index expectile regression
                <sup>
                    <xref ref-type="bibr" rid="ref11">12</xref>
                </sup> referred as &#x201c;ESIM&#x201d;. We simulate data from the model
                <disp-formula id="e18">

                    <mml:math display="block">
                        <mml:msub>
                            <mml:mi>y</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                        <mml:mo>=</mml:mo>
                        <mml:mi>&#x03d5;</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:msubsup>
                                <mml:mi>x</mml:mi>
                                <mml:mi>i</mml:mi>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msubsup>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:mo>+</mml:mo>
                        <mml:mi>&#x03c3;</mml:mi>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:msubsup>
                                <mml:mi>x</mml:mi>
                                <mml:mi>i</mml:mi>
                                <mml:mo>&#x2032;</mml:mo>
                            </mml:msubsup>
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                        <mml:msub>
                            <mml:mi>u</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                        <mml:mo>,</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mo>&#x00a0;</mml:mo>
                        <mml:mi>i</mml:mi>
                        <mml:mo>=</mml:mo>
                        <mml:mn>1</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mo>&#x2026;</mml:mo>
                        <mml:mo>,</mml:mo>
                        <mml:mi>n</mml:mi>
                        <mml:mo>.</mml:mo>
                    </mml:math>

                    <label>(16)</label>
</disp-formula>
            </p>
            <p>The covariates are simulatted independently from the uniform distribution on 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mrow>
                            <mml:mo stretchy="true">[</mml:mo>
                            <mml:mn>0</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>1</mml:mn>
                            <mml:mo stretchy="true">]</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> and 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:msub>
                            <mml:mi>u</mml:mi>
                            <mml:mi>i</mml:mi>
                        </mml:msub>
                    </mml:math>
</inline-formula> is i.i.d. N
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mn>0</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>3</mml:mn>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula>. We experiment with four different scenarios by varying the sample size 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mi>n</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mn>50</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>150</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>250</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>500</mml:mn>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula> and simulations are repeated 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mn>150</mml:mn>
                    </mml:math>
</inline-formula> times for each of given 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>n</mml:mi>
                    </mml:math>
</inline-formula> and 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                        <mml:mspace width="0.25em"/>
                        <mml:mo>&#x2208;</mml:mo>
                        <mml:mspace width="0.25em"/>
                        <mml:mrow>
                            <mml:mo stretchy="true">(</mml:mo>
                            <mml:mn>0.10</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.20</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.30</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.40</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.50</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.60</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.70</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.80</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>0.90</mml:mn>
                            <mml:mo stretchy="true">)</mml:mo>
                        </mml:mrow>
                    </mml:math>
</inline-formula>.</p>
            <sec id="sec7">
                <title>3.1 Simulation 1</title>
                <p>
The simulation setup is similar to Example 1 in
                    <sup>
                        <xref ref-type="bibr" rid="ref10">11</xref>,
                        <xref ref-type="bibr" rid="ref28">29</xref>
                    </sup> with different parameter values for the regression coefficients and error distribution. We generate data sets from model (16), where 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03d5;</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi>s</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mo>sin</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mfrac>
                                    <mml:mrow>
                                        <mml:mi>&#x03c0;</mml:mi>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:mi>s</mml:mi>
                                            <mml:mo>&#x2212;</mml:mo>
                                            <mml:mi>A</mml:mi>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:mrow>
                                    <mml:mrow>
                                        <mml:mi>C</mml:mi>
                                        <mml:mo>&#x2212;</mml:mo>
                                        <mml:mi>A</mml:mi>
                                    </mml:mrow>
                                </mml:mfrac>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>, 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mn>1</mml:mn>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msub>
                                <mml:mo>,</mml:mo>
                                <mml:msub>
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mn>3</mml:mn>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mfrac>
                                <mml:mn>1</mml:mn>
                                <mml:msqrt>
                                    <mml:mn>3</mml:mn>
                                </mml:msqrt>
                            </mml:mfrac>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>,</mml:mo>
                            <mml:mspace width="0.25em"/>
                            <mml:mi>A</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mfrac>
                                <mml:msqrt>
                                    <mml:mn>3</mml:mn>
                                </mml:msqrt>
                                <mml:mn>2</mml:mn>
                            </mml:mfrac>
                            <mml:mo>&#x2212;</mml:mo>
                            <mml:mfrac>
                                <mml:mn>1.645</mml:mn>
                                <mml:msqrt>
                                    <mml:mn>12</mml:mn>
                                </mml:msqrt>
                            </mml:mfrac>
                            <mml:mo>,</mml:mo>
                            <mml:mi>C</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mfrac>
                                <mml:msqrt>
                                    <mml:mn>3</mml:mn>
                                </mml:msqrt>
                                <mml:mn>2</mml:mn>
                            </mml:mfrac>
                            <mml:mo>+</mml:mo>
                            <mml:mfrac>
                                <mml:mn>1.645</mml:mn>
                                <mml:msqrt>
                                    <mml:mn>12</mml:mn>
                                </mml:msqrt>
                            </mml:mfrac>
                            <mml:mo>,</mml:mo>
                            <mml:mspace width="0.25em"/>
                            <mml:mi>&#x03c3;</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msubsup>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msubsup>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.5</mml:mn>
                            <mml:mspace width="0.25em"/>
                            <mml:mtext>and</mml:mtext>
                            <mml:mspace width="0.25em"/>
                            <mml:msub>
                                <mml:mi>u</mml:mi>
                                <mml:mi>i</mml:mi>
                            </mml:msub>
                            <mml:mo>~</mml:mo>
                            <mml:mi>N</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>0</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>3</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>.</p>
                <p>For a Bayesian point estimator we consider the posterior mean using 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mn>15,000</mml:mn>
                        </mml:math>
</inline-formula> iterations of the MCMC after 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mn>1,000</mml:mn>
                        </mml:math>
</inline-formula> iterations as burn-in. The resulting estimates are summarized in boxplot 
                    <xref ref-type="fig" rid="f2">
Figures 2</xref> and 
                    <xref ref-type="fig" rid="f3">3</xref> based on 100 replications. These boxplots display the estimated coefficients, comparing BESIM and ESIM, with
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mspace width="0.25em"/>
                            <mml:mi>&#x03c4;</mml:mi>
                            <mml:mspace width="0.25em"/>
                            <mml:mo>&#x2208;</mml:mo>
                            <mml:mspace width="0.25em"/>
                            <mml:mrow>
                                <mml:mo stretchy="true">{</mml:mo>
                                <mml:mn>0.10</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0.50</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>0.90</mml:mn>
                                <mml:mo stretchy="true">}</mml:mo>
                            </mml:mrow>
                        </mml:math>
</inline-formula>. In general, the boxplots give the impression that the Bayesian estimates (BESIM) produces more precise and stable estimates than classical estimates (ESIM). Mean squared errors (MSE) of the estimates based on the 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mn>100</mml:mn>
                        </mml:math>
</inline-formula> replications in each case are shown in 
                    <xref ref-type="table" rid="T1">
Tables 1</xref> and 
                    <xref ref-type="table" rid="T2">2</xref> for four sample sizes 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>n</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mn>50</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>150</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>250</mml:mn>
                        </mml:math>
</inline-formula> and 500 and all nine expectiles. MSE results show that the proposed method generally behaves better than the ESIM method in terms of the MMAD.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Comparison of MSE results in Simulation 1 for BESIM and ESIM based on 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>150</mml:mn>
                                    <mml:mspace width="0.25em"/>
                                </mml:math>
</inline-formula>replications when 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>50</mml:mn>
                                </mml:math>
</inline-formula> and 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula>.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="3" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <inline-formula>

                                        <mml:math display="inline">
                                            <mml:mi mathvariant="bold-italic">n</mml:mi>
                                            <mml:mo>=</mml:mo>
                                            <mml:mn>50</mml:mn>
                                        </mml:math>
</inline-formula>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <inline-formula>

                                        <mml:math display="inline">
                                            <mml:mi mathvariant="bold-italic">n</mml:mi>
                                            <mml:mo>=</mml:mo>
                                            <mml:mn>150</mml:mn>
                                        </mml:math>
</inline-formula>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                            </tr>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03c4;</italic>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Methods</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0195543</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0147065</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0350343</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0462157</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0091205</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0400359</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0263048</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0181031</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0200267</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0382094</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0276661</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0088778</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0213920</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0170607</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0144794</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0187969</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0431808</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0427004</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0206956</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0167130</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0158080</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0065181</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0360150</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0328985</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0323232</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0316921</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0358028</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0304921</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0359099</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0416645</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0384871</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0459071</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0180494</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0126898</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0031730</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0167676</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0368509</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0341720</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0431401</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0460528</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0293005</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0366979</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0034700</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0044148</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0470265</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030763</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0442098</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0328749</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0350871</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0415319</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0367816</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0481550</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0443593</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0085951</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0017297</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0386636</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0176232</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0442574</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0122571</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0295646</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0133486</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0161901</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0031393</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0488498</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0079065</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0070142</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0124804</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0332511</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0073802</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0203862</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0494447</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0395940</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0091733</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0226894</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0080150</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0022625</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0355585</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0243689</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0253354</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0371858</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0027166</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0086380</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0480610</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0149382</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0363234</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0051813</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0354510</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0325703</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0204459</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0225520</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0371311</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0235138</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0393036</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0218888</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0047231</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0315689</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0463590</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0071871</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0494710</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0213533</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0262922</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0169395</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0440110</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0481442</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0460268</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072926</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0305382</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0360484</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table 2. </label>
                    <caption>
                        <title>Comparison of MSE results in Simulation 1 for BESIM and ESIM based on 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula> replications when 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>250</mml:mn>
                                </mml:math>
</inline-formula> and 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>500</mml:mn>
                                </mml:math>
</inline-formula>.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="3" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">n</italic> = 250</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">n</italic> = 500</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                            </tr>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03c4;</italic>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Methods</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0023184</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0018601</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0160216</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0159654</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016879</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0168082</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0079913</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0161750</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0157870</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0195653</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0146954</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0055722</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0159583</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0151175</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0186634</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0111082</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030300</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0183915</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0044731</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0052732</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0043108</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0126903</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0101296</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0134150</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0100353</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0160354</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0066963</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0165764</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0114315</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0162483</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0101673</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0017985</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0104027</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0147564</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0170205</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0065727</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0125452</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0126779</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0197187</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0097915</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0116293</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0095833</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0098691</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0020233</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0189907</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0141596</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0117513</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0149975</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0022255</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0184194</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0032427</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0015221</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0013674</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0045875</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0145696</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016308</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0183293</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0165074</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0127137</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0040005</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0177884</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0027987</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0158476</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030793</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0110199</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0069175</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0044845</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0135674</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072586</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0103915</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072386</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0132245</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0036283</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0079414</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0104264</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0101376</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0184989</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0047943</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072167</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035641</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0036285</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0013724</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0038420</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0131117</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0149326</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0028020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0024689</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0067298</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0170474</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0179972</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0091541</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0188816</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0172111</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0041089</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0141367</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0104179</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0040758</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0166996</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0122218</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0084545</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0125620</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0037598</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0164282</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0095112</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0040479</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0149395</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0064739</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0199554</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>
Figure 2. </label>
                    <caption>
                        <title>Summarizing estimators of 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>&#x03b2;</mml:mi>
                                    <mml:mspace width="0.25em"/>
                                </mml:math>
</inline-formula>for 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>50</mml:mn>
                                    <mml:mo>,</mml:mo>
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula> in Simulation 1. &#x2018;BESIM
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>50</mml:mn>
                                </mml:math>
</inline-formula>&#x2019; denotes BESIM with 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>50</mml:mn>
                                </mml:math>
</inline-formula>, for example. </title>
                        <p>500 and all nine expectiles. MSE results show that the proposed method generally behaves better than the ESIM method in terms of the MMAD.</p>
                    </caption>
                    <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/192635/e7ed66e4-18e7-433a-8d86-8788ec3aac96_figure2.gif"/>
                </fig>
                <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                    <label>
Figure 3. </label>
                    <caption>
                        <title>Summarizing estimators of 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>&#x03b2;</mml:mi>
                                </mml:math>
</inline-formula> for 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>250</mml:mn>
                                    <mml:mo>,</mml:mo>
                                    <mml:mn>500</mml:mn>
                                </mml:math>
</inline-formula> in Simulation 1. &#x2018;BESIM
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>250</mml:mn>
                                </mml:math>
</inline-formula>&#x2019; denotes BESIM with 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi>n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>250</mml:mn>
                                </mml:math>
</inline-formula>, for example.</title>
                    </caption>
                    <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/192635/e7ed66e4-18e7-433a-8d86-8788ec3aac96_figure3.gif"/>
                </fig>
            </sec>
            <sec id="sec8">
                <title>3.2 Simulation 2</title>
                <p>In this simulation study, we simulate data from model (16), where 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03b2;</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo>,</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:msqrt>
                                <mml:mn>3</mml:mn>
                            </mml:msqrt>
                        </mml:math>
</inline-formula> and 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>&#x03c3;</mml:mi>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msubsup>
                                    <mml:mi>x</mml:mi>
                                    <mml:mi>i</mml:mi>
                                    <mml:mo>&#x2032;</mml:mo>
                                </mml:msubsup>
                                <mml:mi>&#x03b2;</mml:mi>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:msqrt>
                                <mml:mrow>
                                    <mml:mn>1</mml:mn>
                                    <mml:mo>+</mml:mo>
                                    <mml:mo>sin</mml:mo>
                                    <mml:mrow>
                                        <mml:mo stretchy="true">(</mml:mo>
                                        <mml:msubsup>
                                            <mml:mi>x</mml:mi>
                                            <mml:mi>i</mml:mi>
                                            <mml:mo>&#x2032;</mml:mo>
                                        </mml:msubsup>
                                        <mml:mi>&#x03b2;</mml:mi>
                                        <mml:mo stretchy="true">)</mml:mo>
                                    </mml:mrow>
                                </mml:mrow>
                            </mml:msqrt>
                        </mml:math>
</inline-formula>. Mean squared errors (MSE) of the estimates based on the 100 replications in each case are shown in 
                    <xref ref-type="table" rid="T3">
Tables 3</xref> and 
                    <xref ref-type="table" rid="T4">4</xref> for four sample sizes 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mi>n</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mn>50</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>150</mml:mn>
                            <mml:mo>,</mml:mo>
                            <mml:mn>250</mml:mn>
                        </mml:math>
</inline-formula> and 
                    <inline-formula>

                        <mml:math display="inline">
                            <mml:mn>500</mml:mn>
                        </mml:math>
</inline-formula> and all nine expectiles. Again, MSE results show that the proposed method generally behaves better than the ESIM method in terms of the MSE.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Comparison of MSE results in Simulation 2 for BESIM and ESIM based on 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula> replications when 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>50</mml:mn>
                                </mml:math>
</inline-formula> and 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula>.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="3" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <inline-formula>

                                        <mml:math display="inline">
                                            <mml:mi mathvariant="bold-italic">n</mml:mi>
                                            <mml:mo>=</mml:mo>
                                            <mml:mn>50</mml:mn>
                                        </mml:math>
</inline-formula>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <inline-formula>

                                        <mml:math display="inline">
                                            <mml:mi mathvariant="bold-italic">n</mml:mi>
                                            <mml:mo>=</mml:mo>
                                            <mml:mn>150</mml:mn>
                                        </mml:math>
</inline-formula>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                            </tr>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03c4;</italic>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Methods</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0107191</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0180942</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0194673</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0175731</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0155628</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0063909</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0245536</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0102368</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0204030</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0240220</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0154682</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035139</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0231226</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072586</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0189763</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0061164</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0018900</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0075795</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0127013</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0232348</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072481</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0059392</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0160106</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0013501</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0117925</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0122501</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0109938</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0181383</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0151146</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0077859</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0204627</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0240346</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0167902</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0168055</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0094831</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0111475</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0234465</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0021388</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0167361</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0099125</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0242583</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0018942</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0037376</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049627</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0183407</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049792</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0217180</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0238382</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0184912</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0019595</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0114310</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0163468</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0084606</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0191856</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0156928</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0132497</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0158988</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0136745</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0229315</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0227252</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016549</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0216356</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030284</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0153109</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0218318</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0242549</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0073266</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0215684</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0159264</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0199063</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0069357</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0141723</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0151522</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0102854</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0222214</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0124963</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0045482</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0173132</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0126653</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0068737</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0053582</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0053046</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0069645</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0223847</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0249352</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0028472</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0135214</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0220645</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0126694</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0234537</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0152664</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0064641</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0151681</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0194387</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0052556</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0020447</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0100017</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0205785</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0157309</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0045215</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0080002</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0154013</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0056914</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0147402</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0067066</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0078914</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0214991</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0227348</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <table-wrap id="T4" orientation="portrait" position="float">
                    <label>
Table 4. </label>
                    <caption>
                        <title>Comparison of MSE results in Simulation 2 for BESIM and ESIM based on 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mn>150</mml:mn>
                                </mml:math>
</inline-formula> replications when 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>250</mml:mn>
                                </mml:math>
</inline-formula> and 
                            <inline-formula>

                                <mml:math display="inline">
                                    <mml:mi mathvariant="bold-italic">n</mml:mi>
                                    <mml:mo>=</mml:mo>
                                    <mml:mn>500</mml:mn>
                                </mml:math>
</inline-formula>.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="3" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">n</italic> = 250</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">n</italic> = 500</th>
                                <th align="left" colspan="1" rowspan="1" valign="top"/>
                            </tr>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03c4;</italic>
</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Methods</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>1</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>2</sub>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">&#x03b2;</italic>
                                    <sub>3</sub>
                                </th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035559</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0060365</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0092645</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0040971</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0023224</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0074677</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.10</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0072896</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030640</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0059215</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0029716</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0019371</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0031230</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0091081</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0018402</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0054281</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0089195</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0095040</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0096261</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.20</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0074059</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0087256</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0075169</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0022337</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0012525</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0078955</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0099915</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049505</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0088972</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0021822</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0085752</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0096027</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.30</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0073508</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0032648</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0090581</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0068663</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0038764</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0060716</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0078945</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0029055</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0065168</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0087705</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0017163</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0084206</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.40</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0086904</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0068451</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0020872</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0097546</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0031230</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0025890</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0071910</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0029777</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0058355</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0085510</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016177</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0033637</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.50</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0010848</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0023306</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0045046</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049204</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0033204</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0098460</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0020000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0027075</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0017791</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035235</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0059186</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0024654</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.60</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035538</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035468</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0095305</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0047394</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0077648</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0060467</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0077003</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0082037</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0055475</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0020283</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0044568</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049402</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.70</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0035222</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0033758</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0043629</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0017790</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0050371</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0083322</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0024182</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0021317</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0063671</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0056524</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016956</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0046949</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.80</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0045966</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0031001</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0023693</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0055960</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0085606</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0049265</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0097013</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0016838</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0098522</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0029054</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0098691</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0033133</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.90</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0090078</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0079991</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0064896</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0056303</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0067910</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">0.0030292</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
        </sec>
        <sec id="sec9">
            <title>4. Boston housing data</title>
            <p>We examine the proposed method using the Boston Housing data (BHD). BHD was collected by
                <sup>
                    <xref ref-type="bibr" rid="ref8">9</xref>
                </sup> in a study regarding the impact of clean air on housing prices, which is available in the R package spdep. BHD contains information collected from a random sample of size 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mn>506</mml:mn>
                    </mml:math>
</inline-formula> population census areas in the Boston city. The description of the variables is summarized in 
                <xref ref-type="table" rid="T5">
Table 5</xref>.</p>
            <table-wrap id="T5" orientation="portrait" position="float">
                <label>
Table 5. </label>
                <caption>
                    <title>Description of covariates in the BHD.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top">Covariate</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">
Description</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>1</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Crime rate per capita by city</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>2</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Percentage of residential land allocated to land exceeding 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mn>25,000</mml:mn>
                                    </mml:math>
</inline-formula> square feet.</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>3</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Percentage of non-retail space per city</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>4</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Fictitious variable for the Charles River</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>5</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Nitric oxide concentration</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>6</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Average number of rooms per dwelling</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>7</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Percentage of owner-occupied dwellings built before 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mn>1940</mml:mn>
                                    </mml:math>
</inline-formula>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>8</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Weighted distances to five employment centers in Boston</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>9</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Radial highway accessibility index</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>10</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Full property tax rate per 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mtext mathvariant="italic">$</mml:mtext>
                                        <mml:mn>10,000</mml:mn>
                                    </mml:math>
</inline-formula>
</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>11</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ratio of students to teachers by city</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>12</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mn>1000</mml:mn>
                                        <mml:msup>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:msub>
                                                    <mml:mi>B</mml:mi>
                                                    <mml:mi>k</mml:mi>
                                                </mml:msub>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:mn>0</mml:mn>
                                                <mml:mo>.63</mml:mo>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mn>2</mml:mn>
                                        </mml:msup>
                                    </mml:math>
</inline-formula> where 
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:msub>
                                            <mml:mi>B</mml:mi>
                                            <mml:mi>k</mml:mi>
                                        </mml:msub>
                                    </mml:math>
</inline-formula> is the proportion of Black residents</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">x</italic>
                                <sub>13</sub>
                            </td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Decline in population %</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <italic toggle="yes">y</italic>
</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">
                                <inline-formula>

                                    <mml:math display="inline">
                                        <mml:mn>0</mml:mn>
                                        <mml:mo>.50</mml:mo>
                                    </mml:math>
</inline-formula> quantiles of the owner-occupied dwellings</td>
                        </tr>
                    </tbody>
                </table>
            </table-wrap>
            <table-wrap id="T6" orientation="portrait" position="float">
                <label>
Table 6. </label>
                <caption>
                    <title>MSE based on 
                        <inline-formula>

                            <mml:math display="inline">
                                <mml:mn>5</mml:mn>
                            </mml:math>
</inline-formula>-fold cross-validation results for the BHD.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top">Method</th>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top">Test error</th>
                            <th align="left" colspan="4" rowspan="1" valign="top"/>
                        </tr>
                        <tr>
                            <th align="left" colspan="1" rowspan="1" valign="top"/>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>1</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>2</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>3</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>4</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>5</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>6</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>7</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>8</th>
                            <th align="left" colspan="1" rowspan="1" valign="top">

                                <italic toggle="yes">&#x03c4;</italic> = 0
                                <italic toggle="yes">.</italic>9</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">ESIM</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.053</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.053</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.052</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.051</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.050</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.052</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.052</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.053</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.053</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">BESIM</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.046</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.046</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.044</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.042</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.040</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.045</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.046</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.045</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">0.046</td>
                        </tr>
                    </tbody>
                </table>
            </table-wrap>
            <p>Similar as in 
                <xref ref-type="table" rid="T1">
Tables 1</xref>, 
                <xref ref-type="table" rid="T2">2</xref>, 
                <xref ref-type="table" rid="T3">3</xref>, and 
                <xref ref-type="table" rid="T4">4</xref>, we consider nine choices of 
                <inline-formula>

                    <mml:math display="inline">
                        <mml:mi>&#x03c4;</mml:mi>
                        <mml:mo>=</mml:mo>
                        <mml:mn>0.1</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0.2</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0.3</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0.4</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0.5</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0</mml:mn>
                        <mml:mo>.</mml:mo>
                        <mml:mn>6</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0</mml:mn>
                        <mml:mo>.</mml:mo>
                        <mml:mn>7</mml:mn>
                        <mml:mo>,</mml:mo>
                        <mml:mn>0</mml:mn>
                        <mml:mo>.</mml:mo>
                        <mml:mn>8</mml:mn>
                        <mml:mo>&#x00a0;</mml:mo>
                    </mml:math>
</inline-formula> and 0.9. we consider 5-fold cross-validation to evaluate the performance of the both approaches (ESIM and BESIM). It can be seen that the BESIM performs better than its non-Bayesian counterpart, ESIM, uniformly for all expectiles considered.</p>
        </sec>
        <sec id="sec10" sec-type="conclusion">
            <title>5. Conclusion</title>
            <p>Single-index expectile regression models provide a flexible semiparametric regression frame-work for high-dimensional covariates, and capture parameter heterogeneity and nonlinearity especially when focusing on different parts of the conditional distribution of the outcome of interest. In this paper, we introduce the Bayesian expectile regression with single-index model. A Bayesian hierarchical formulation is developed for expectile regression with single-index model (BESIM). Simulations and real data studies show that BESIM generally perform better compared with ESIM.</p>
        </sec>
        <sec id="sec11">
            <title>Ethical considerations</title>
            <p>This study does not involve human participants or animals, therefore ethical approval was not required.</p>
        </sec>
        <sec id="sec15" sec-type="data-availability">
            <title>Data availability</title>
            <p>The underlying data is available in Zenodo. 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.18479534">https://doi.org/10.5281/zenodo.18479534</ext-link>
                <sup>
                    <xref ref-type="bibr" rid="ref29">1</xref>
                </sup>
            </p>
            <p>Data are available under the terms of the 
                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International license</ext-link> (CC-BY 4.0).</p>
        </sec>
        <sec id="sec12">
            <title>Software availability</title>
            <p>The R code supporting the findings of this study is openly available in the Zenodo repository at: 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.18681405">https://doi.org/10.5281/zenodo.18681405</ext-link>.
                <sup>
                    <xref ref-type="bibr" rid="ref30">30</xref>
                </sup>
            </p>
            <p>This code is also accessible via GitHub at: 
                <ext-link ext-link-type="uri" xlink:href="https://github.com/zena158/Bayesian-Single-Index-Expectile-Regression/tree/v1.0.1">https://github.com/zena158/Bayesian-Single-Index-Expectile-Regression/tree/v1.0.1</ext-link>.</p>
        </sec>
    </body>
    <back>
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