<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="systematic-review" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.178740.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Systematic Review</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Digital transformation as a driver of operational sustainability in manufacturing: a systematic review (2015&#x2013;2025)</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 3 approved, 1 approved with reservations]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Cruz Salinas</surname>
                        <given-names>Luis Edgardo</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-3856-3146</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Macalop&#x00fa; Rimachi</surname>
                        <given-names>Jessica</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Sandoval Reyes</surname>
                        <given-names>Carlos Jos&#x00e9;</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>La Libertad, Universidad Cesar Vallejo, Chep&#x00e9;n, La Libertad, 13871, Peru</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:lcruzs@ucv.edu.pe">lcruzs@ucv.edu.pe</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>16</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2026</year>
            </pub-date>
            <volume>15</volume>
            <elocation-id>544</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>14</day>
                    <month>3</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Cruz Salinas LE et al.</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/15-544/pdf"/>
            <abstract>
                <sec>
                    <title>Objective</title>
                    <p>This research examines how the adoption of digital technologies&#x2014;the Internet of Things (IoT), artificial intelligence, digital twins, and big data analytics&#x2014;affects operational sustainability in the manufacturing sector.</p>
                </sec>
                <sec>
                    <title>Design/methodology</title>
                    <p>A systematic review was conducted in accordance with the PRISMA 2020 guidelines, consulting Scopus, ScienceDirect and Taylor &amp; Francis for the period 2015&#x2013;2025. Of 1,247 initial records, 50 studies passed the eligibility and methodological quality filters.</p>
                </sec>
                <sec>
                    <title>Findings</title>
                    <p>The evidence indicates that the joint implementation of several digital technologies produces reductions of between 20% and 35% in energy consumption and between 25% and 40% in material waste, according to the ranges reported in the primary studies. Digital twins had the greatest effects on process optimisation, followed by industrial IoT and artificial intelligence systems. Organisations that combined three or more complementary technologies achieved improvements 40%&#x2013;60% greater than isolated implementations.</p>
                </sec>
                <sec>
                    <title>Originality</title>
                    <p>The work offers a structured synthesis of the specific mechanisms that connect digitalisation with concrete sustainability indicators and identifies knowledge gaps that guide future lines of research.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>digital transformation</kwd>
                <kwd>operational sustainability</kwd>
                <kwd>manufacturing industry</kwd>
                <kwd>digital twins</kwd>
                <kwd>Industry 4.0</kwd>
                <kwd>systematic review</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1">
                    <funding-source>Universidad C&#x00e9;sar Vallejo</funding-source>
                </award-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec id="sec5" sec-type="intro">
            <title>I. Introduction</title>
            <p>The manufacturing sector today operates under dual pressure: to remain competitive in global markets while reducing its environmental footprint (
                <xref ref-type="bibr" rid="ref8">Chiarini and Kumar, 2021</xref>; 
                <xref ref-type="bibr" rid="ref19">Luthra et al., 2020</xref>). This sector generates approximately 16% of global GDP and employs hundreds of millions of workers, so any advances in its sustainability practices have far-reaching economic and social repercussions (
                <xref ref-type="bibr" rid="ref37">Xi et al., 2024</xref>; 
                <xref ref-type="bibr" rid="ref1">Ahmadi-Gh and Bello-Pintado, 2024</xref>).</p>
            <p>Technologies associated with Industry 4.0&#x2014;industrial IoT, artificial intelligence, digital twins, big data analytics, and cyber-physical systems&#x2014;have been proposed as the strategic response to this dual challenge (
                <xref ref-type="bibr" rid="ref3">Attaran et al., 2024</xref>; 
                <xref ref-type="bibr" rid="ref12">Dong et al., 2025</xref>). In theory, these tools make it possible to monitor resource consumption in real time, anticipate failures using predictive models, and optimise production configurations without shutting down the plant. However, the literature shows that effective adoption remains uneven and that the links between digitalisation and operational sustainability are not fully documented (
                <xref ref-type="bibr" rid="ref11">De Felice et al., 2024</xref>; 
                <xref ref-type="bibr" rid="ref27">Pigola et al., 2025</xref>; 
                <xref ref-type="bibr" rid="ref18">Kiel et al., 2017</xref>).</p>
            <p>This research revolves around the question: how does digital transformation contribute to the operational sustainability of the manufacturing industry during the period 2015&#x2013;2025? To answer this question, a systematic review of scientific literature was designed that: (a) identifies the digital technologies with the greatest impact on operational sustainability indicators; (b) compares the effectiveness of integrated approaches versus isolated implementations; and (c) detects knowledge gaps that limit the generalisation of results.</p>
            <p>Interest in this intersection has grown rapidly. 
                <xref ref-type="bibr" rid="ref19">Luthra et al. (2020)</xref> identified Industry 4.0 as a catalyst for sustainable practices in the supply chains of emerging economies. Subsequently, 
                <xref ref-type="bibr" rid="ref8">Chiarini and Kumar (2021)</xref> showed that combining Lean Six Sigma with Industry 4.0 tools led to measurable reductions in waste and energy consumption in Italian companies. 
                <xref ref-type="bibr" rid="ref12">Dong et al. (2025)</xref> documented that Chinese companies with broad digital adoption developed more green innovation capabilities than those with partial implementations. More recently, 
                <xref ref-type="bibr" rid="ref33">Singh et al. (2024)</xref> applied grey influence analysis (GINA) to assess the role of digital twins in the resilience of manufacturing supply chains.</p>
            <p>However, significant gaps remain. There are few longitudinal studies documenting the evolution of benefits over time. Most of the evidence comes from Europe and Asia-Pacific, with little representation from Latin America and Africa. Furthermore, there is a lack of standardised evaluation frameworks that allow for the comparison of results across different sectors and geographical contexts. This review aims to contribute to closing these gaps through a synthesis that integrates findings from 50 empirical and theoretical studies selected using strict quality criteria.</p>
        </sec>
        <sec id="sec6">
            <title>II. Theoretical framework</title>
            <sec id="sec7">
                <title>Global context of sustainable manufacturing</title>
                <p>The convergence of environmental regulation, consumer expectations and climate goals has placed manufacturing at the centre of decarbonisation efforts (
                    <xref ref-type="bibr" rid="ref13">Ghobakhloo et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref22">Monroy-Osorio, 2024</xref>). The 2030 Agenda and, in particular, SDGs 9 (industry, innovation and infrastructure) and 12 (responsible production and consumption) provide the regulatory framework that guides these transformations. In practice, manufacturing companies must reconcile the pressure to reduce costs with the need to invest in less polluting processes (
                    <xref ref-type="bibr" rid="ref4">Bag et al., 2023</xref>; 
                    <xref ref-type="bibr" rid="ref36">Strandhagen et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref32">Sharma et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref30">Sartal et al., 2020</xref>).</p>
                <p>The available evidence suggests that organisations that manage to align their digitalisation strategy with environmental objectives not only preserve their competitiveness but also develop advantages that are difficult to imitate, in line with the theory of dynamic capabilities (
                    <xref ref-type="bibr" rid="ref1">Ahmadi-Gh and Bello-Pintado, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref40">Zekhnini et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref15">Hermawan et al., 2024</xref>). However, this assertion is still based on cross-sectional studies; causal confirmation requires longitudinal designs that are not yet sufficiently available in the literature.</p>
            </sec>
            <sec id="sec8">
                <title>Fundamentals of digital transformation in manufacturing</title>
                <p>Digital transformation is not limited to the ad hoc adoption of devices or software. As characterised by 
                    <xref ref-type="bibr" rid="ref26">Paul et al. (2024)</xref>, 
                    <xref ref-type="bibr" rid="ref3">Attaran et al. (2024)</xref> and 
                    <xref ref-type="bibr" rid="ref13">Ghobakhloo et al. (2025)</xref>, it is a redesign of processes, structures and business models that leverages connectivity, automation and data intelligence. The main technological pillars include:</p>
                <p>Industrial IoT enables the connection of machines, sensors and control systems to collect real-time operational data. Artificial intelligence and machine learning transform this data into energy consumption predictions, early fault detection and optimal production planning (
                    <xref ref-type="bibr" rid="ref22">Monroy-Osorio, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref28">Rosa et al., 2020</xref>). Digital twins&#x2014;virtual replicas of physical systems&#x2014;enable the simulation of alternative production scenarios without stopping operations, facilitating experimentation with more efficient configurations (
                    <xref ref-type="bibr" rid="ref33">Singh et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref2">Atalay et al., 2022</xref>). For its part, big data analytics extracts patterns of inefficiency that would remain invisible with conventional methods.</p>
                <p>
                    <xref ref-type="bibr" rid="ref23">N&#x00fa;&#x00f1;ez-Merino et al. (2020)</xref> and 
                    <xref ref-type="bibr" rid="ref7">Chiarini et al. (2020)</xref> showed that these technologies function as enablers of lean principles: by providing total visibility of the process, they allow waste to be eliminated with greater precision. 
                    <xref ref-type="bibr" rid="ref17">Karadayi-Usta (2024)</xref> extended this idea to the field of additive manufacturing, where the digitisation of the supply chain is a prerequisite for effective waste reduction.</p>
            </sec>
            <sec id="sec9">
                <title>Operational sustainability: a multidimensional construct</title>
                <p>In this paper, operational sustainability is defined as the ability of a manufacturing organisation to maintain increasing levels of production while simultaneously minimising the use of natural resources, waste generation and emissions, without compromising economic viability or the well-being of surrounding communities (
                    <xref ref-type="bibr" rid="ref27">Pigola et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref11">De Felice et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref6">Chen et al., 2024</xref>).</p>
                <p>This conceptualisation integrates the three dimensions of the Triple Bottom Line&#x2014;economic, environmental, and social&#x2014;and translates them into the realm of day-to-day operations. 
                    <xref ref-type="bibr" rid="ref21">Mishra et al. (2024)</xref> developed and validated a scale that connects different dimensions of digitalisation with specific sustainability outcomes in the value chain. Their work provided quantitative evidence that digital traceability throughout the supply chain is positively associated with reductions in emissions and waste.</p>
            </sec>
            <sec id="sec10">
                <title>Integration between digitalisation and sustainability: accumulated evidence</title>
                <p>Between 2015 and 2025, the literature has shifted from linear models&#x2014;where technology was conceived as an input for efficiency&#x2014;to systemic frameworks that recognise interdependencies between technologies, organisational capabilities, and institutional context (
                    <xref ref-type="bibr" rid="ref37">Xi et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref27">Pigola et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref35">Stock and Seliger, 2016</xref>).</p>
                <p>
                    <xref ref-type="bibr" rid="ref8">Chiarini and Kumar (2021)</xref> documented in Italian companies that combining Lean Six Sigma with digital tools produced greater reductions in waste and energy consumption than those obtained by each approach separately. 
                    <xref ref-type="bibr" rid="ref12">Dong et al. (2025)</xref> found, in a sample of Chinese companies, that the breadth of digitalisation had a greater impact on environmental resilience than the depth of implementation of a single technology. 
                    <xref ref-type="bibr" rid="ref36">Strandhagen et al. (2022)</xref> applied this logic to the shipbuilding sector and confirmed that digitalisation addressed sustainability challenges specific to resource-intensive industries. 
                    <xref ref-type="bibr" rid="ref4">Bag et al. (2023)</xref> further identified that digital technologies not only improve efficiency but also generate new capabilities for reuse and recycling (
                    <xref ref-type="bibr" rid="ref39">Zaid et al., 2025</xref>).</p>
                <p>The dynamic capabilities model (
                    <xref ref-type="bibr" rid="ref37">Xi et al., 2024</xref>) and open innovation frameworks (
                    <xref ref-type="bibr" rid="ref33">Singh et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref20">Maldonado-Guzm&#x00e1;n and Pinz&#x00f3;n-Castro, 2023</xref>; 
                    <xref ref-type="bibr" rid="ref5">Bokrantz et al., 2020</xref>) offer a plausible explanation: companies that combine technological investment with internal skills development and external collaboration generate self-reinforcing sustainability advantages. However, this theoretical explanation needs further mpirical validation.</p>
            </sec>
            <sec id="sec11">
                <title>Connection with the Sustainable Development Goals</title>
                <p>Digital technologies contribute to SDG 9 by facilitating efficient, resilient industrial infrastructures with a lower carbon footprint (
                    <xref ref-type="bibr" rid="ref13">Ghobakhloo et al., 2025</xref>). With regard to SDG 12, tools such as digital twins and blockchain-based traceability make it possible to monitor the environmental impact of a product throughout its life cycle, which promotes more informed production and consumption decisions (
                    <xref ref-type="bibr" rid="ref17">Karadayi-Usta, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref22">Monroy-Osorio, 2024</xref>). Although the literature suggests that digitalisation can simultaneously drive several SDGs, it should be noted that the realisation of this potential depends on the strategic design of each implementation and on contextual factors that vary between regions and sectors.</p>
            </sec>
        </sec>
        <sec id="sec12">
            <title>III. Methodology</title>
            <sec id="sec13">
                <title>Study design</title>
                <p>A systematic literature review was conducted following the PRISMA 2020 guidelines (
                    <xref ref-type="bibr" rid="ref24">Page et al., 2021</xref>). The objective was to synthesise the available evidence on the relationship between the implementation of digital technologies and operational sustainability in manufacturing during the period 2015&#x2013;2025.</p>
            </sec>
            <sec id="sec14">
                <title>Search strategy</title>
                <p>The search was conducted in three databases: Scopus, ScienceDirect and Taylor &amp; Francis Online, selected for their coverage of high-impact journals in engineering, management and sustainability. The following combination of Boolean operators was used:</p>
                <p>(&#x201c;digital transformation&#x201d; OR &#x201c;digitalisation&#x201d; OR &#x201c;Industry 4.0&#x201d; OR &#x201c;digital technologies&#x201d;) AND (&#x201c;sustainability&#x201d; OR &#x201c;sustainable manufacturing&#x201d; OR &#x201c;operational sustainability&#x201d; OR &#x201c;environmental performance&#x201d;) AND (&#x201c;manufacturing&#x201d; OR &#x201c;manufacturing industry&#x201d; OR &#x201c;production systems&#x201d;) AND (&#x201c;operational efficiency&#x201d; OR &#x201c;operational performance&#x201d; OR &#x201c;process optimisation&#x201d;)</p>
                <p>Filters were applied for period (2015&#x2013;2025), language (English and Spanish) and document type (peer-reviewed journal articles). Conference proceedings, books, theses and grey literature were excluded (
                    <xref ref-type="bibr" rid="ref29">Sagala and &#x0150;ri, 2024</xref>).</p>
            </sec>
            <sec id="sec15">
                <title>Inclusion and exclusion criteria</title>
                <p>
                    <xref ref-type="table" rid="T1">
Table 1</xref> presents the inclusion and exclusion criteria applied in this review. Articles were included if they focused on digital technologies within the scope of Industry 4.0 and their effects on operational sustainability in manufacturing, were published in peer-reviewed journals between 2015 and 2025, and were written in English or Spanish.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Inclusion and exclusion criteria.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Criterion</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Inclusion</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Exclusion</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Temporality</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Published between 2015 and 2025</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Outside the range or speculative projections</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Theme</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Explicit relationship between digitalisation and sustainability in manufacturing</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Digitalisation or sustainability addressed in isolation</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Type of publication</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Articles in peer-reviewed indexed journals</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Technical reports, white papers, conference proceedings</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Sector</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Manufacturing industry or proven applicability</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Exclusively service, agriculture or construction sectors</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Access</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Full text available</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Restricted access preventing full evaluation</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <bold>Quality</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Rigorous methodology and transparent reporting</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Serious methodological shortcomings</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec id="sec16">
                <title>Methodological quality assessment</title>
                <p>Each study was independently evaluated by two reviewers using a checklist adapted from 
                    <xref ref-type="bibr" rid="ref41">Downs and Black (1998)</xref> for quantitative studies and 
                    <xref ref-type="bibr" rid="ref42">Tracy (2010)</xref> for qualitative studies. The criteria evaluated included: clarity in the definition of constructs, validity of instruments, adequacy of sample size, transparency in data reporting, and control of confounding variables. A scale of 0 to 10 was used, with scores of 7 or above classified as high quality, between 5 and 6 as moderate quality, and below 5 as low quality. Discrepancies were resolved by consensus between reviewers or, when necessary, with the intervention of a third evaluator.</p>
            </sec>
            <sec id="sec17">
                <title>Selection process: PRISMA flow</title>
                <p>
                    <xref ref-type="fig" rid="f1">
Figure 1</xref> presents the flow diagram according to the PRISMA 2020 model. The initial search yielded 1,247 records. After removing 367 duplicates, 880 titles and abstracts were screened, of which 634 were discarded for not meeting the inclusion criteria. A total of 246 full texts were retrieved (8 were inaccessible), and of the 238 evaluated, 188 were excluded for the reasons detailed in the figure. The final sample consisted of 50 studies.</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>
Figure 1. </label>
                    <caption>
                        <title>PRISMA 2020 flow diagram of the study selection process.</title>
                        <p>The diagram illustrates the identification, screening, and inclusion stages, showing the number of records at each stage and the reasons for exclusion. A total of 1,247 records were identified; after removing duplicates and applying eligibility criteria, 50 studies were included in the final synthesis.</p>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure1.gif"/>
                </fig>
            </sec>
            <sec id="sec18">
                <title>Synthesis of results</title>
                <p>Given the heterogeneity of designs (quantitative, qualitative, and mixed studies), a structured narrative synthesis complemented by thematic analysis was chosen. The information was organised into three areas: (a) digital technologies implemented and their mechanisms of influence; (b) sustainability indicators affected; and (c) moderating contextual factors. A standardised data extraction form was completed for each study.</p>
            </sec>
        </sec>
        <sec id="sec19" sec-type="results">
            <title>IV. Results</title>
            <sec id="sec20">
                <title>Profile of the studies included</title>
                <p>The 50 studies cover a variety of sectors: automotive (28%), electronics (22%), food (18%), textiles (14%), chemicals and pharmaceuticals (12%) and others (6%). In terms of the size of the organisations studied, 44% analysed large multinationals, 38% focused on SMEs, and 18% used mixed samples. The geographical distribution reflects differences in adoption maturity: Europe accounts for 32% of the studies, Asia-Pacific 28%, North America 24%, Latin America 12% and Africa 4% (
                    <xref ref-type="bibr" rid="ref38">Yildiztekin et al., 2023</xref>; 
                    <xref ref-type="bibr" rid="ref34">Song et al., 2022</xref>). 
                    <xref ref-type="fig" rid="f2">
Figure 2</xref> shows the evolution of publications over time, 
                    <xref ref-type="fig" rid="f3">
Figure 3</xref> presents the distribution by journal of publication, and 
                    <xref ref-type="fig" rid="f4">
Figure 4</xref> presents the geographical distribution.</p>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>
Figure 2. </label>
                    <caption>
                        <title>Annual scientific output of the studies included in the review (2015&#x2013;2025).</title>
                        <p>The bar chart shows the number of studies published per year, illustrating the rapid growth of research at the intersection of digital transformation and operational sustainability in manufacturing, particularly from 2020 onwards.</p>
                    </caption>
                    <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure2.gif"/>
                </fig>
                <fig fig-type="figure" id="f3" orientation="portrait" position="float">
                    <label>
Figure 3. </label>
                    <caption>
                        <title>Distribution of studies by journal of publication.</title>
                        <p>The chart shows the journals that contributed the most studies to this review, highlighting the interdisciplinary nature of the field across production engineering, sustainability, and management journals.</p>
                    </caption>
                    <graphic id="gr3" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure3.gif"/>
                </fig>
                <fig fig-type="figure" id="f4" orientation="portrait" position="float">
                    <label>
Figure 4. </label>
                    <caption>
                        <title>Geographical distribution of the studies included in the review.</title>
                        <p>The map illustrates the uneven representation across regions, with Europe (32%), Asia-Pacific (28%), and North America (24%) accounting for the majority of studies, and Latin America (12%) and Africa (4%) underrepresented.</p>
                    </caption>
                    <graphic id="gr4" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure4.gif"/>
                </fig>
            </sec>
            <sec id="sec21">
                <title>Digital technologies evaluated and their effectiveness</title>
                <p>
                    <xref ref-type="table" rid="T2">
Table 2</xref> summarises the technologies studied, their frequency, and the ranges of improvement reported in the primary studies. Digital twins were the most frequently analysed technology (22% of studies) and showed the greatest effects on process optimisation: reductions of between 25% and 35% in energy consumption and between 20% and 30% in material use, according to 
                    <xref ref-type="bibr" rid="ref33">Singh et al. (2024)</xref> and 
                    <xref ref-type="bibr" rid="ref3">Attaran et al. (2024)</xref>. Industrial IoT (20%) facilitated continuous monitoring, with improvements of between 15% and 25% in resource utilisation. AI systems (18%) excelled in predictive planning, with reductions in operating costs of between 22% and 32% according to 
                    <xref ref-type="bibr" rid="ref25">Parida et al. (2024)</xref>. Big data analytics (16%) enabled the detection of hidden patterns of inefficiency, generating energy savings of between 18% and 26% (
                    <xref ref-type="bibr" rid="ref16">Kamble et al., 2020</xref>). 
                    <xref ref-type="fig" rid="f5">
Figure 5</xref> illustrates the comparative effectiveness of these technologies across sustainability indicators.</p>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table 2. </label>
                    <caption>
                        <title>Effectiveness of digital technologies in operational sustainability indicators.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Technology</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Studies (%)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Energy efficiency</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Waste reduction</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Cost reduction</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Digital twins</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">22</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">25&#x2013;35</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">20&#x2013;30</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">18&#x2013;25%</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Industrial IoT</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">20</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">15&#x2013;25</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">18&#x2013;28</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">15&#x2013;22</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">AI/Machine learning</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">18</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">20&#x2013;30</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">22&#x2013;32</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">22&#x2013;32</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Big data analytics</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">16</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">18&#x2013;26</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">25&#x2013;40</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">16&#x2013;24</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Automation/robotics</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">14</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">12&#x2013;20</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">15&#x2013;25</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">20&#x2013;30</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Blockchain traceability</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">10</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">8&#x2013;15</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">8&#x2013;12</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">10&#x2013;18</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <fig fig-type="figure" id="f5" orientation="portrait" position="float">
                    <label>
Figure 5. </label>
                    <caption>
                        <title>Comparative effectiveness of digital technologies in operational sustainability.</title>
                        <p>The chart presents the mean improvement ranges reported in the included studies for each technology category (digital twins, industrial IoT, AI, blockchain, additive manufacturing), across three sustainability dimensions: energy efficiency, waste reduction, and operating cost reduction.</p>
                    </caption>
                    <graphic id="gr5" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure5.gif"/>
                </fig>
            </sec>
            <sec id="sec22">
                <title>Comparison between traditional, individual and integrated approaches</title>
                <p>The most relevant contrast that emerges from the review is the difference in performance between three strategies: the traditional approach (reactive management based on historical data), the implementation of a single digital technology, and the integrated approach that combines three or more complementary technologies. Comparative studies indicate that organisations with integrated approaches achieved improvements of between 30% and 45% in energy efficiency, compared to between 8% and 15% with traditional approaches. Similarly, recovery times from operational disruptions were between 40% and 60% shorter in digitally mature organisations. 
                    <xref ref-type="fig" rid="f6">
Figure 6</xref> illustrates this comparison.</p>
                <fig fig-type="figure" id="f6" orientation="portrait" position="float">
                    <label>
Figure 6. </label>
                    <caption>
                        <title>Comparison of improvements by type of approach: traditional, partially digital, and fully integrated.</title>
                        <p>The figure illustrates that organisations adopting fully integrated digital approaches achieved sustainability improvements 40%&#x2013;60% greater than those with traditional or fragmented implementations.</p>
                    </caption>
                    <graphic id="gr6" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/197164/6d0e0957-6650-4bf4-a72e-76068d5f1aa1_figure6.gif"/>
                </fig>
                <p>One additional piece of data deserves attention: 78% of organisations classified as digitally mature reported successful circular economy initiatives (reuse or recycling), compared to 34% of those with traditional approaches.</p>
            </sec>
            <sec id="sec23">
                <title>Impact on organisational practice</title>
                <p>The aggregate results show improvements in four dimensions. In energy efficiency, studies report reductions of between 20% and 35%, with peaks of up to 45% when digital twins were combined with IoT. In material optimisation, waste reductions ranged from 25% to 40%, with improvements in inventory utilisation of between 30% and 50%. In environmental indicators, greenhouse gas emissions decreased between 22% and 38%, and industrial waste generation between 28% and 45%. Regarding regulatory compliance, 89% of the organisations studied reported improvements after implementing digital traceability systems. 
                    <xref ref-type="table" rid="T3">
Table 3</xref> summarises the contribution of the identified digital technologies to specific Sustainable Development Goals.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Contribution of digital transformation to the Sustainable Development Goals.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">SDG</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Identified contribution</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Key technologies</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Evidence</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">SDG 9: Industry and innovation</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Resilient infrastructure, sustainable industrialisation</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Digital twins, IoT, AI</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <xref ref-type="bibr" rid="ref13">Ghobakhloo et al. (2025)</xref>; 
                                    <xref ref-type="bibr" rid="ref14">Hasan Emon and Khan (2025)</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">SDG 12: Responsible production</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Circular economy, life cycle traceability</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">Blockchain, data analytics</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <xref ref-type="bibr" rid="ref17">Karadayi-Usta (2024)</xref>; 
                                    <xref ref-type="bibr" rid="ref22">Monroy-Osorio (2024)</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="middle">SDG 13: Climate action</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">GHG emissions reduction in manufacturing</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">IoT, digital twins</td>
                                <td align="left" colspan="1" rowspan="1" valign="middle">
                                    <xref ref-type="bibr" rid="ref12">Dong et al. (2025)</xref>; 
                                    <xref ref-type="bibr" rid="ref34">Song et al. (2022)</xref>
                                </td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec id="sec24">
                <title>Sectoral differences</title>
                <p>Effectiveness varied across sectors. The automotive and electronics industries achieved the greatest relative benefits, probably due to their greater technological maturity. The food industry showed notable progress in waste reduction and cold chain optimisation. The textile sector stood out in water and energy efficiency. Geographically, Europe and Asia-Pacific reported more mature implementations, although organisations in Latin America and Africa that achieved successful implementations showed proportionally higher rates of improvement, pointing to opportunities for technological acceleration in emerging economies (
                    <xref ref-type="bibr" rid="ref3">Sepp et al., 2024</xref>).</p>
            </sec>
        </sec>
        <sec id="sec25" sec-type="discussion">
            <title>V. Discussion</title>
            <sec id="sec26">
                <title>Summary of key findings</title>
                <p>The results of this review confirm that combining several digital technologies produces greater sustainability benefits than each technology alone. This pattern is consistent with dynamic capabilities theory (
                    <xref ref-type="bibr" rid="ref37">Xi et al., 2024</xref>) and with previous evidence from 
                    <xref ref-type="bibr" rid="ref8">Chiarini and Kumar (2021)</xref> on the synergies between lean approaches and digital tools. The prominence of digital twins as the technology with the greatest impact validates the predictions of 
                    <xref ref-type="bibr" rid="ref33">Singh et al. (2024)</xref> regarding their role in supply chain resilience.</p>
                <p>One finding that deserves special attention is the difference between breadth and depth of digitalisation. 
                    <xref ref-type="bibr" rid="ref12">Dong et al. (2025)</xref> found that breadth&#x2014;understood as the number of digitised processes&#x2014;had a greater impact on environmental resilience than the depth of implementation of a single technology. Our results reinforce this observation: organisations with integrated approaches (three or more technologies) consistently outperformed those that invested in a single tool, however sophisticated it may have been.</p>
            </sec>
            <sec id="sec27">
                <title>Comparison with previous studies</title>
                <p>The reported improvements for IoT (15%&#x2013;25% in resource utilisation) are consistent with the findings of 
                    <xref ref-type="bibr" rid="ref19">Luthra et al. (2020)</xref>, who identified this technology as a key enabler of sustainability in supply chains. However, our ranges are somewhat more conservative than those of previous studies, which may reflect the maturation of the field and the inclusion of more recent and rigorous empirical data.</p>
                <p>The case of blockchain is illustrative. While the initial narrative attributed transformative potential to it, the aggregate data show modest effects (8%&#x2013;15% in energy efficiency). This suggests that the technology needs a more developed ecosystem&#x2014;including interoperability standards and a critical mass of participants&#x2014;to achieve the promised benefits.</p>
            </sec>
            <sec id="sec28">
                <title>Knowledge gaps and limitations</title>
                <p>This review identified three main gaps. First, the scarcity of longitudinal studies: most of the evidence comes from cross-sectional studies that do not capture the evolution of benefits over time. Second, uneven geographical representation: Europe and Asia-Pacific account for 60% of the studies, whil nd Latin America account for only 16%. Third, the absence of standardised evaluation frameworks that allow for direct comparison of results across sectors and regions.</p>
                <p>The limitations of the study itself must be noted transparently. The restriction to three databases may have excluded relevant studies published in sources not indexed in Scopus, ScienceDirect, or Taylor &amp; Francis. The decision to conduct a narrative synthesis rather than a meta-analysis is due to the heterogeneity of designs and metrics, but limits the quantitative accuracy of the conclusions. Likewise, the inclusion of articles from 2025 that are not yet fully indexed introduces some uncertainty about the comprehensiveness of the sample for that year.</p>
            </sec>
            <sec id="sec29">
                <title>Emerging challenges and future lines of research</title>
                <p>The findings suggest at least four lines of future work. First, longitudinal designs that document the evolution of sustainability benefits over three or more years following digital implementation. Second, comparative studies between geographical contexts with different levels of development, including middle- and low-income economies. Third, interdisciplinary research incorporating perspectives from organisational psychology and sociology of work to understand human barriers to technology adoption. Fourth, exploration of emerging technologies&#x2014;such as generative artificial intelligence and quantum computing&#x2014;and their potential impact on manufacturing sustainability.</p>
            </sec>
            <sec id="sec30">
                <title>Implications for practice</title>
                <p>For manufacturing executives, the main operational conclusion is that investments in digitalisation for sustainability generate both environmental and economic returns, with operating cost reductions of between 18% and 32%. However, these benefits materialise more strongly when implementation is integrated rather than fragmented. SMEs, with more limited resources, can start with low-complexity IoT systems before scaling up to more sophisticated solutions.</p>
                <p>For public policymakers, the results underscore the importance of designing regulatory frameworks and incentives that facilitate technology adoption, particularly in emerging economies where infrastructure and training gaps are more pronounced.</p>
            </sec>
        </sec>
        <sec id="sec31" sec-type="conclusions">
            <title>VI. Conclusions</title>
            <p>This systematic review of 50 studies published between 2015 and 2025 yields three main conclusions. First, the joint implementation of digital technologies&#x2014;especially digital twins, IoT, and artificial intelligence&#x2014;generates measurable improvements in energy efficiency (20%&#x2013;35%), waste reduction (25%&#x2013;40%), and operating costs (18%&#x2013;32%). Second, integrated approaches consistently outperform isolated implementations, with gains between 40% and 60% higher in sustainability indicators. Third, significant gaps remain: longitudinal studies are lacking, geographical representation is uneven, and standardised evaluation frameworks do not exist.</p>
            <p>The study contributes to knowledge by offering a structured synthesis of the mechanisms that connect digitalisation with operational sustainability and by explicitly mapping the gaps that future research should address. For business practice, the central message is that digitalisation and sustainability are not parallel agendas but mutually reinforcing when designed in an integrated manner.</p>
            <p>The future research agenda should prioritise longitudinal designs, comparative studies between regions with different levels of development, interdisciplinary research on human and organisational barriers, and the evaluation of emerging technologies such as generative artificial intelligence. Only through this expansion of knowledge will it be possible to more accurately guide the transition to genuinely sustainable manufacturing in the digital age.</p>
        </sec>
    </body>
    <back>
        <sec id="sec34" sec-type="data-availability">
            <title>Data availability</title>
            <p>This article is a systematic review. All data supporting the results reported in the article are available within the article itself and its supplementary materials. The list of included studies and the data extraction tables are available as Extended Data files accompanying this submission. The underlying datasets from the primary studies reviewed are available in their respective original publications, all of which are cited in the reference list. No new primary datasets were generated for this study. The PRISMA 2020 checklist for this review has been uploaded as a supplementary file and is available at: 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.31585258">https://doi.org/10.6084/m9.figshare.31585258</ext-link> (
                <xref ref-type="bibr" rid="ref9">Cruz Salinas, et al., 2025a</xref>).</p>
            <p>This dataset is available under a 

                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0 licence</ext-link>.</p>
            <sec id="sec35">
                <title>Extended data</title>
                <p>Extended Data 
                    <xref ref-type="table" rid="T1">
Table 1</xref>. Full data extraction table for the 50 included studies, including study design, digital technologies analysed, sustainability outcomes reported, and methodological quality scores. Available at: 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.31585795">https://doi.org/10.6084/m9.figshare.31585795</ext-link> (
                    <xref ref-type="bibr" rid="ref10">Cruz Salinas, et al., 2025b</xref>).</p>
                <p>This dataset is available under a 
                    <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0 licence</ext-link>
.</p>
            </sec>
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    <sub-article article-type="reviewer-report" id="report475966">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.197164.r475966</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Abu Bakar</surname>
                        <given-names>Nur Azaliah</given-names>
                    </name>
                    <xref ref-type="aff" rid="r475966a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-0464-5810</uri>
                </contrib>
                <aff id="r475966a1">
                    <label>1</label>Universiti Teknologi Malaysia, Skudai, Johor, Malaysia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>13</day>
                <month>6</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Abu Bakar NA</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport475966" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.178740.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This systematic review examines the role of digital transformation technologies, including Industrial IoT, artificial intelligence, digital twins, big data analytics, automation, and blockchain, in improving operational sustainability within the manufacturing sector. Following PRISMA 2020 guidelines, the authors reviewed literature published between 2015 and 2025 and synthesized evidence from 50 studies selected from an initial pool of 1,247 records. The review aims to identify the technologies with the greatest sustainability impact, compare isolated versus integrated digital implementations, and identify knowledge gaps for future research.</p>
            <p> The rationale and objectives of the review are clearly stated. The manuscript establishes the importance of sustainable manufacturing and the growing role of Industry 4.0 technologies in addressing environmental and operational challenges. The research questions and review objectives are explicitly defined and aligned with the scope of the study.</p>
            <p> The methodology generally follows accepted systematic review practices and includes database selection, search terms, inclusion and exclusion criteria, quality assessment procedures, and a PRISMA flow diagram. However, the level of methodological detail remains insufficient for full replication. The manuscript does not provide the exact search strings used in each database, the search dates, database-specific adaptations, detailed quality assessment scoring results, or inter-rater agreement statistics. Although a quality appraisal process is described, the operationalisation of the adapted Downs and Black and Tracy criteria is not reported in sufficient detail. These elements should be added to enhance transparency and reproducibility.</p>
            <p> The statistical analysis is only partly satisfactory. The study appropriately employs a narrative synthesis because of the heterogeneity of study designs and outcome measures. However, the manuscript reports numerous quantitative improvement ranges, percentages, and comparative performance figures without fully explaining how these values were aggregated across studies. Since no formal meta-analysis was conducted, the basis for calculating average improvements and comparative effectiveness should be clarified. The authors should explicitly state whether these values represent reported ranges from primary studies, weighted averages, or descriptive summaries derived during synthesis.</p>
            <p> The conclusions are generally supported by the evidence presented. The review consistently demonstrates that integrated digital transformation initiatives outperform isolated technology implementations and are associated with improvements in energy efficiency, waste reduction, operational performance, and sustainability outcomes. The discussion appropriately acknowledges limitations related to geographical representation, lack of longitudinal evidence, database coverage, and methodological heterogeneity. These limitations provide an appropriate context for interpreting the findings.</p>
            <p> To strengthen the scientific rigor of the review, the authors should address several points. First, provide complete and reproducible search protocols, including database-specific search strings and search dates. Second, report detailed methodological quality assessment results for all included studies. Third, clarify how quantitative improvement ranges and comparative percentages were synthesized across the included studies. Fourth, provide a more detailed explanation of how the narrative and thematic synthesis procedures were conducted. Finally, several numerical claims should be presented more cautiously because they are derived from heterogeneous studies and should not be interpreted as pooled effect estimates.</p>
            <p> Overall, the review addresses an important and timely topic, presents a coherent synthesis of the literature, and offers useful implications for manufacturing sustainability. Subject to improvements in methodological transparency and clarification of the quantitative synthesis procedures, the article provides a valuable contribution to the field of digital transformation and sustainable manufacturing.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Yes</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Artificial Intelligence, Data Analytics, Enterprise Architecture, Digital Transformation, Information Systems Governance, Educational Technology, Cybersecurity, and Higher Education Internationalisation.</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report475971">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.197164.r475971</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Le&#x00f3;n Luyo</surname>
                        <given-names>Sandra Lizzette</given-names>
                    </name>
                    <xref ref-type="aff" rid="r475971a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-5683-3392</uri>
                </contrib>
                <aff id="r475971a1">
                    <label>1</label>Universidad Nacional de Trujillo, Trujillo, Peru</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>5</day>
                <month>5</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Le&#x00f3;n Luyo SL</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport475971" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.178740.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>When conducting a study based on a systematic review of information from 2015 to 2025, following the PRISMA 2020 protocol, on topics related to core Industry 4.0 technologies &#x2014;such as industrial IoT, artificial intelligence, digital twins, and big data analytics&#x2014; it becomes possible to visualize how these technologies influence the sustainable performance of a sector sustained by global GDP figures. Likewise, the findings are precise and applicable, indicating that the use of these technologies promotes a reduction in energy consumption of between 20% and 35%, and that the generation of material waste decreases between 25% and 40%; these figures are particularly relevant for business decision-makers as well as for those responsible for developing public policies aimed at meeting SDGs 9 and 12. On the other hand, the study highlights the scarcity of longitudinal studies and the low participation of research from Latin America and Africa, giving rise to the need to close academic gaps, for which reason a more inclusive and long-term research agenda is recommended.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>No</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Environmental culture, finance, entrepreneurship, international trade</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report479087">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.197164.r479087</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Marquez Yauri</surname>
                        <given-names>Heyner Yuliano</given-names>
                    </name>
                    <xref ref-type="aff" rid="r479087a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-1825-9542</uri>
                </contrib>
                <aff id="r479087a1">
                    <label>1</label>Universidad Nacional de Trujillo, Trujillo, Peru</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>30</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Marquez Yauri HY</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport479087" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.178740.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This article analyzes how digital transformation drives sustainability in manufacturing through a systematic literature review (2015-2025). The study is relevant given the current need for companies to be both competitive and sustainable. Despite the inherent limitations of heterogeneous research designs and the geographical diversity of the analyzed studies, this work offers a key combination of insights into how digital technologies optimize production processes and reduce environmental impact.</p>
            <p> Methodologically, the article demonstrates solid methodological rigor by adhering to the PRISMA 2020 guidelines, a gold standard for systematic reviews.</p>
            <p> While the study contributes to knowledge by offering a structured synthesis of the mechanisms connecting digitalization with operational sustainability, it overlooks or fails to address the mechanisms or barriers that limit this connection (critical challenges). Although not the study's objective, this is an aspect that should be clarified or addressed.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>No</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Business strategiesDigital transformation and marketingInternational tradeSustainability and environmental cultureEntrepreneurship and innovationEducational management</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report479088">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.197164.r479088</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Hutahayan</surname>
                        <given-names>Benny</given-names>
                    </name>
                    <xref ref-type="aff" rid="r479088a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0001-6904-7817</uri>
                </contrib>
                <aff id="r479088a1">
                    <label>1</label>University of Brawijaya, Malang, East Java, Indonesia</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>29</day>
                <month>4</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Hutahayan B</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport479088" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.178740.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>Introduction</p>
            <p> - The research gap needs to be further clarified. Currently, the gap is primarily presented as a list of general limitations, such as the lack of longitudinal studies and geographical representation, but has not yet been fully articulated as a scientific gap that directly justifies the need for this systematic review.</p>
            <p> - The novelty of the research has not been explicitly stated. The authors need to clarify what distinguishes this review from previous review studies, for example, in terms of the time period covered, the focus on operational sustainability, or the comparison between integrated and partial implementation. &#x00a0;</p>
            <p> - The 2015&#x2013;2025 timeframe has been mentioned, but no sufficiently strong justification has been provided. The authors need to explain why this period was chosen and its relevance to the development of Industry 4.0 in manufacturing.</p>
            <p> </p>
            <p> Methodology</p>
            <p> - The search strategy needs to be described in greater detail to ensure it can be replicated, including the search date, search fields (title, abstract, keywords), and whether the search syntax was tailored for each database.</p>
            <p> - The inclusion and exclusion criteria are mentioned in the manuscript, but the authors need to provide a justification for why and on what basis these criteria were established. This explanation is necessary to strengthen the manuscript.</p>
            <p> - The quality assessment section demonstrates efforts to maintain methodological rigor through two independent reviewers, but the assessment procedures still need to be described in more operational terms. The authors need to explain in greater detail how the instruments from Downs and Black (1998) and Tracy (2010) were adapted, which items were used, and how the quality scores were calculated. Therefore, the authors need to provide the results of the quality assessment in detail.</p>
            <p> </p>
            <p> 
                <bold>- </bold>The discussion section
                <bold> </bold>has begun to link the review&#x2019;s findings to theory and prior research, particularly dynamic capabilities theory and previous studies on the synergy between lean approaches and digital tools. Comparisons with prior studies are present but could be expanded to be more systematic. The discussion of the relationship between the findings and dynamic capabilities theory remains relatively brief. If this theory is indeed the primary foundation, then the author needs to demonstrate this more explicitly.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Not applicable</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Business Administration, Human Resources Management, Law, and Governance</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
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