<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="systematic-review" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.179684.2</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Systematic Review</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Emerging Technologies in Higher Education Course Development: A Systematic Review of Design Frameworks, Learning Outcomes, and Pedagogical Integration</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 2; peer review: 1 approved, 2 approved with reservations]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Geleto Wariyo</surname>
                        <given-names>Lemecha</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-1733-7809</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Abame</surname>
                        <given-names>Addise</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Lolamo</surname>
                        <given-names>Abebe</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0009-0007-3670-1772</uri>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Bekene</surname>
                        <given-names>Tola</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-1828-3582</uri>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Bekele</surname>
                        <given-names>Jabe</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Psychology, Wachemo University, Hosaena, Central Ethiopia Region, 667, Ethiopia</aff>
                <aff id="a2">
                    <label>2</label>English Language and Literature, Wachemo University, Hosaena, Central Ethiopia Region, 667, Ethiopia</aff>
                <aff id="a3">
                    <label>3</label>Mathematics, Wachemo University, Hosaena, Central Ethiopia Region, 667, Ethiopia</aff>
                <aff id="a4">
                    <label>4</label>Educational Planning and Management, Wachemo University, Hosaena, Central Ethiopia Region, 667, Ethiopia</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:lemechageleto@yahoo.com">lemechageleto@yahoo.com</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>1</day>
                <month>6</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2026</year>
            </pub-date>
            <volume>15</volume>
            <elocation-id>716</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>25</day>
                    <month>5</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Geleto Wariyo L et al.</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/15-716/pdf"/>
            <abstract>
                <p>This review explored the impact of technology on course design, student learning outcomes, and engagement in higher education. The major enablers and barriers to implementation are also discussed. Following the PRISMA 2020 procedure, the systematic review integrated findings from 76 peer-reviewed empirical studies from 1996 to 2025. A mixed-method narrative and quantitative synthesis supported by statistical conversions mean standardized effect estimate (Cohen&#x2019;s d) to enable cross-study comparison was used. Results showed that technology-involved instruction could be most effective with integration of an existing instructional design model. Technological Pedagogical Content Knowledge (TPACK); Utilization of Constructive Alignment (CA); Analyze, Design, Develop, Implement, and Evaluate (ADDIE), Design-Based Research (DBR) revealed moderate-to-high effects on learning outcome (d&#x00a0;=&#x00a0;0.65-0.74), while deep learning model with embedded artificial intelligence (AI) and mixed/extended reality (MR) reported the highest effect (d&#x00a0;=&#x00a0;1.30). For technology categories, the strongest effects on learning and engagement observed at immersive technologies (AR/VR/MR) (g&#x00a0;=&#x00a0;0.98), followed by AI, and learning analytics (g&#x00a0;=&#x00a0;0.62), and game-based learning (g&#x00a0;=&#x00a0;0.71). Improvement in engagement was common across studies, while long-term behavioral and transfer effects were little observed. Success indicators identified were pedagogical alignment, institutional readiness, faculty competence, learner preparedness, whereas the challenges were infrastructure constraints, digital divides, and inadequate longitudinal evaluation. Synthesizing these through the lens of socio-technical systems perspective, results indicate that educational effectiveness is outcome of the relationship between technological affordances, pedagogical design, and organizational capacity.</p>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Course development; Emerging Technology; Design framework; Learning outcomes; Pedagogical Integration</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1" xlink:href="https://doi.org/10.13039/501100021787">
                    <funding-source>Wachemo University</funding-source>
                    <award-id>WCU-T08</award-id>
                </award-group>
                <funding-statement>We declare that the work was funded by Wachemo University with Funding Number: WCU-T08 </funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
        <notes>
            <sec sec-type="version-changes">
                <label>Updated</label>
                <title>Changes from Version 1</title>
                <p>This manuscript presents a systematic review with a descriptive quantitative synthesis examining how emerging technologies and instructional design frameworks are integrated into higher education course development. The review analyzes diverse pedagogical models, technological interventions, and educational settings to identify trends in learning outcomes, implementation practices, and institutional considerations. The quantitative synthesis was intended to support comparative interpretation across studies rather than a formal meta-analysis. When sufficient statistical data were available, outcomes were converted to a common standardized metric (Cohen&#x2019;s d) to facilitate comparison. However, because the included studies varied considerably in design, intervention duration, participant characteristics, technologies, outcome measures, and reporting quality, effect estimates were descriptively aggregated using arithmetic means instead of inverse-variance weighted meta-analytic methods. Accordingly, the manuscript uses terms such as &#x201c;descriptive aggregated effect estimates&#x201d; and &#x201c;mean standardized effect estimates&#x201d; to avoid overstating statistical precision. The findings should therefore be interpreted cautiously as indicative trends rather than definitive estimates of instructional effectiveness or causal impact. Formal heterogeneity testing, confidence intervals, publication bias analyses, and risk-of-bias synthesis were not conducted due to inconsistent methodological reporting across studies. To improve transparency and reproducibility, the manuscript provides detailed descriptions of database searches, screening criteria, reviewer agreement procedures, effect-size conversions, and study selection processes consistent with PRISMA guidelines. Inter-rater reliability was assessed using intra-class correlation coefficients under a two-way random-effects model with absolute agreement. Generally, the reviewed literature reflects a rapidly evolving field shaped by technological innovation, diverse institutional contexts, and heterogeneous pedagogical practices. The review aims to provide conceptual synthesis and evidence-informed interpretation while highlighting the need for future rigorous meta-analyses and longitudinal experimental research.</p>
            </sec>
        </notes>
    </front>
    <body>
        <sec id="sec1" sec-type="intro">
            <title>Introduction</title>
            <sec id="sec2">
                <title>Study background</title>
                <p>The higher education system is rapidly changing due to technological advances, global digitalization and changing learner demands. Universities face increasing pressure to integrate new technologies in teaching, learning and program development to bring about significant change in the knowledge economy. Technologies like AI, augmented and virtual reality (AR/VR), learning analytics (LA), mobile learning platforms, and gamified digital environments are recognized as integral components of current education systems (
                    <xref ref-type="bibr" rid="ref5">Alfredo et al., 2024</xref>). These tools are being promoted for their potential to improve student engagement, support flexible and personalized learning paths, enhancing digital literacy integration of educational outcomes embedded with skills needed in data-driven job market (
                    <xref ref-type="bibr" rid="ref61">Olaniyan &amp; Uzorka, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al., 2023</xref>). Apart from classical learning management system, new technologies, which are immersive, interactive and data-driven, allow institutions to experiment with more advanced and authentic manner. Adaptive systems have the capability to address the needs of individual learners, offer feedback in real time, and encourage interaction (
                    <xref ref-type="bibr" rid="ref30">Guerrero-Rold&#x00e1;n et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref45">Ling &amp; Chiang, 2022</xref>).</p>
                <p>While promising, the use of emerging technologies in higher education is challenging pedagogically, ethically, and practically. In many institutions, integration of technology is still piecemeal and often seen as an afterthought, rather than a cohesive part of course design and pedagogy (
                    <xref ref-type="bibr" rid="ref18">Bond et al., 2020</xref>). Infrastructure access is not the only determinant of the success of technology-related initiatives, as teacher readiness, institutional support systems, and student digital capability also influence such success (
                    <xref ref-type="bibr" rid="ref61">Olaniyan &amp; Uzorka, 2024</xref>). Technology interventions are at risk of not improving learning outcomes and could add inefficiencies, inequities, or additional work for students and faculty without accompanying them by systematic planning and grounding them in educational theory and practice. Thus, in the design, delivery and assessment of courses, structured educational theories/models need to be applied so that technology is a facilitator of meaningful learning but not a replacement for good teaching.</p>
                <p>Recent research highlights the importance of pedagogy in technology integration. According to the TPACK model, successful technology use in education is shaped by the interaction among knowledge of the technology, pedagogical issues and the subject matter in question (
                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>; 
                    <xref ref-type="bibr" rid="ref10">Asamoah, 2019</xref>). CA also gives significance to aligning intended learning outcomes (ILOs), teaching and learning methods and assessment types, to facilitate meaningful learning experience (
                    <xref ref-type="bibr" rid="ref16">Biggs et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref35">Hristov et al., 2023</xref>). When applied to emerging technologies, use of these models implies that course design moves toward purposefully integrating digital tools with discipline-specific goals and providing instructors with adequate professional development and institutional support. This coordination helps to ensure technology advancement in line with promoting fruitful learning.</p>
                <p>Even as digital tools have become more readily available, many efforts are still fruitless, with limited institutional policy and professional development support (
                    <xref ref-type="bibr" rid="ref6">Alhazzaa &amp; Yan, 2025</xref>). Thus, it is evident that there is a necessity to distil empirical evidence to identify the types of technologies that are most effective, the conditions under which they are likely to be linked to positive learning outcome, and the strategies that can assist them in integrating systematically into processes of course development and evaluation. In Ethiopia, national-level policy documents and academic studies have shown an increasing focus on digitalization in higher education from 2015 to 2025. A significant move was the development and launching of Ethiopia&#x2019;s Digital Education Strategy (2023&#x2013;2028) in 2024 by the Ministry of Education with support from partners, such as UNICEF, the International Telecommunication Union (ITU), the World Bank, and the Mastercard Foundation (
                    <xref ref-type="bibr" rid="ref55">Ministry of Education &amp; Mastercard Foundation, 2024</xref>). The strategy outlines nine focus areas for capacity building in digital education systems, including ones to encourage open-source educational technologies, to create curriculum-based digital learning materials, to raise digital competencies of learners and teachers, and to build data governance and analytics for evidence-driven policy decisions (
                    <xref ref-type="bibr" rid="ref55">Ministry of Education &amp; Mastercard Foundation, 2024</xref>). These priorities send a clear message at the national level, that the government seeks a robust digital education ecosystem that provides the foundation for innovation, collaboration, and knowledge sharing among institutions.</p>
                <p>The strategy also sets out 35 implementing measures related to the development of infrastructure and the provision of digital learning materials. Measures range from improving wireless internet access in universities, providing access to digital devices such as tablets and projectors, and promoting domestic production of assistive technologies (
                    <xref ref-type="bibr" rid="ref55">Ministry of Education &amp; Mastercard Foundation, 2024</xref>). The strategy also signifies the expansion of the Ethiopian Education and Research Network (EthERNet) as a reliable broadband backbone for communication, research cooperation and resource sharing among universities in the context of higher education and a nationwide educational cloud system envisioned as a potential one to help in digital platforms and management of institutional data. The Ministry&#x2019;s Executive Desk for Methodology of ICT and Digital Education is empowered with obligations concerning the formulation of the digital policy, the administration of the development of digital libraries, and the fostering of the e-learning program in the nation.</p>
                <p>According to scholars, Ethiopian higher education, &#x201c;has been historically characterized by prioritizing expansion of physical facilities over transformation of teaching practices.&#x201d; Lecture-mode instruction continues to dominate, limiting opportunities for enhancement of critical thinking and problem-solving skills (
                    <xref ref-type="bibr" rid="ref34">Hassen, 2025</xref>), who advocates a shift to more learner-centered pedagogies that is facilitated by digital technologies. Previous studies also evidence persistent gaps in digital literacy: 
                    <xref ref-type="bibr" rid="ref82">Woreta et al. (2013)</xref> revealed that only about half of the healthcare students in the University of Gondar possessed sufficient skills in ICT and even fewer were frequent users of key digital tools like emails and office software. The enduring inadequacies in digital capabilities continue to hinder contemporary attempts of transformation.</p>
                <p>Yet, indigenous technology development in Ethiopia indicates a bright future for adopting cutting-edge digital technologies in Tertiary Education. 
                    <xref ref-type="bibr" rid="ref31">Hailu and Welay (2024)</xref> created an Amharic-language chatbot with approximately 91 percent accuracy through deep learning and natural language processing. Although it is initially aimed at administrative support, this is an example of how AI-based solutions can enhance student services, institutional efficiency, and the creation of technology-enabled learning spaces. These kinds of developments are evidence that local technical capacity is existent.</p>
                <p>Analyses of national documents and researches demonstrate identical themes in relations to institutional readiness, learning outcomes enhancement, and scalability. Ethiopian literature although it seldom explicitly refers to educational design models such as TPACK and CA, generally focuses on the development of infrastructure, technology acceptance, and institutional capacity as positive drivers for successful digital transformation (
                    <xref ref-type="bibr" rid="ref55">Ministry of Education &amp; Mastercard Foundation, 2024</xref>). This focus shows that funding is frequently directed toward acquisition of technological hardware, as opposed to pedagogically informed course development, offering minimal assistance with productive use in the classroom. Research on technology readiness and acceptance also shows that digital approaches may not remain engaging when course design does not take into account the needs, skills, and motivations of students and teachers (
                    <xref ref-type="bibr" rid="ref40">Kalmpourtzis &amp; Romero, 2020</xref>; 
                    <xref ref-type="bibr" rid="ref23">Dejene &amp; Tilahun, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref57">Mitiku et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref73">Sharma et al., 2025</xref>).</p>
                <p>There is evidence of ongoing challenges in systemic capacity building as higher education in Ethiopia has been characterized by chronic infrastructural inadequacies, lack of competent ICT man power and diversity in faculty preparedness to engage in sustainable technology integration (
                    <xref ref-type="bibr" rid="ref1">Adamu, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref27">Feye, 2025</xref>). Equity and access issues in rural and marginalized areas also impede the development of inclusive digital education systems (
                    <xref ref-type="bibr" rid="ref55">Ministry of Education &amp; Mastercard Foundation, 2024</xref>). While policy frameworks tend to support public-private partnerships and the creation of local content, there are fewer further developed approaches to translate these initiatives into pedagogically sound educational practices.</p>
            </sec>
            <sec id="sec3">
                <title>Research questions</title>
                <p>Motivated by the need to harmonize technological advances with teaching and learning efficiency, the review aims to answer these main research questions: 1) how are courses designed with new technologies? 2) How do these technologies influence student learning outcomes and engagement? and 3) Which contextual, institutional and/or pedagogical factors determine success?</p>
            </sec>
            <sec id="sec4">
                <title>Significance of the review</title>
                <p>Firstly, while the focus of earlier meta-analyses and reviews mainly concentrated on technology adoption or acceptance, this review is mainly focused on integrating findings across emerging technologies to enable a holistic view to the rapidly evolving digital technologies in course design and development in higher education institutions (HEIs). Empirical based insights are critical for informing evidence-based course development as universities increase investments in digital infrastructure and pedagogical innovation, and as they are encouraged not to implement emerging technologies purely for the sake of novelty, but instead to use these tools in ways that enhance the quality of learning, support equity, and improve graduate employability outcomes (
                    <xref ref-type="bibr" rid="ref71">Sakr &amp; Abdullah, 2024</xref>). Secondly, for instructional designers and faculty, having a familiarity with the empirical bases of successful digital learning approaches facilitates the development of more engaging, inclusive, and pedagogically sound courses. Thirdly, the review facilitates the ongoing debate at a global level on the digital transformation of higher education by highlighting the relevance of context-appropriate models for sustainable implementation, which balance technological innovation with sound pedagogical principles, and identify key enablers such as professional development, institutional preparedness, and student support as well as a range of persistent issues that include scalability, cost, and methodological rigor. Situated against the backdrop of rapid developments in generative AI, immersive simulations, and data-driven personalization, the review provides a platform for future investigations on how these technologies may influence not only learning outcomes but also the fundamental elements of curriculum design, faculty roles, and student agency in higher education.</p>
            </sec>
        </sec>
        <sec id="sec5">
            <title>Methodology</title>
            <sec id="sec6">
                <title>Research design and review protocol</title>
                <p>This review adheres to the PRISMA 2020 (
                    <xref ref-type="bibr" rid="ref63">Page et al., 2021</xref>) procedure and statement. Due to variability of interventions and study designs within the emergent educational technologies domain, a narrative synthesis and determination of mean effect sizes were used. This enabled the integration of quantitative, qualitative, and mixed-method findings to capture the multifaceted nature of course development in higher education. Two key questions guided the focus of the review: (a) what empirical research is available on the design and delivery of degree-level courses incorporating emergent technologies; and (b) to consider the educational outcomes and contextual factors influencing success or failure. The review is, therefore, a blend of description mapping (technologies types, disciplines, geographical spread) with thematic aggregation (engagement, learning gains, and institutional readiness).</p>
            </sec>
            <sec id="sec7">
                <title>Eligibility criteria</title>
                <p>The inclusion and exclusion criteria were specified in advance to ensure methodological rigor.</p>
                <p>

                    <bold>Inclusion criterion.</bold> Regarding the inclusion criteria, the studies had to be empirical, take place in higher education (universities, colleges, polytechnics), and involve undergraduate, postgraduate, or professional education. Research addressed emerging technologies for course design, development, and instruction. These spanned from AR/VR, MR, gamification, AI, machine learning, adaptive learning systems, LAs, mobile or ubiquitous learning environment, just to name a few emergent pedagogical technologies going beyond traditional learning management system (LMS) application. Only peer-reviewed empirical studies employing quantitative or qualitative methodologies or mixed methods, quasi-experimental studies, DBR and case study methodologies reporting implementation outcomes were taken into account. Pertinent findings encompassed learning outcomes and engagement. To capture a decade of fast growing technological advancement, literature was searched from 1996 to 2025, and only studies written in English language were considered.</p>
                <p>

                    <bold>Exclusion criterion</bold>. Reviews were excluded if: 1) they were set entirely within K-12 schools; 2) they were conceptual or theoretical work, including commentaries or reviews; 3) they involved technology acceptance or attitudes research without an explicitly stated connection to course design; and 4) the papers were not peer-reviewed or were methodologically opaque. These criteria were established so that the included studies would offer empirical rather than anecdotal data on the application of technology to the course development process.</p>
            </sec>
            <sec id="sec8">
                <title>Searching techniques</title>
                <p>In order to detect the relevant studies, we conducted the search in the databases, such as Scopus, Web of Science, ERIC, ScienceDirect, and Google Scholar. Search words were different combinations of course, developing, technology, e-learning, and higher education. We employed some key words, such as course development, curriculum design, instructional design, emerging technology, digital innovation, virtual reality, augmented reality, AI, LA, adaptive learning, gamification, mobile e-learning, Universities, higher education, and college.</p>
                <p>The general search strings used in the review are:
                    <disp-quote>
                        <p>(&#x201c;TPACK&#x201d; OR &#x201c;Technological Pedagogical Content Knowledge&#x201d; OR &#x201c;Constructive Alignment&#x201d; OR ADDIE OR &#x201c;Design-Based Research&#x201d; OR DBR OR &#x201c;instructional design framework*&#x201d; OR &#x201c;pedagogical framework*&#x201d; OR &#x201c;learning design framework*&#x201d; OR &#x201c;course design model*&#x201d; OR &#x201c;technology integration framework*&#x201d; OR &#x201c;hybrid framework*&#x201d; OR &#x201c;integrated framework*&#x201d;)</p>
                        <p>AND</p>
                        <p>(&#x201c;educational technology&#x201d; OR &#x201c;technology-enhanced learning&#x201d; OR TEL OR &#x201c;digital learning&#x201d; OR e-learning OR &#x201c;online learning&#x201d; OR &#x201c;blended learning&#x201d; OR &#x201c;mobile learning&#x201d; OR m-learning OR &#x201c;adaptive learning&#x201d; OR &#x201c;learning analytics&#x201d; OR &#x201c;artificial intelligence&#x201d; OR AI OR &#x201c;generative AI&#x201d; OR ChatGPT OR &#x201c;large language model*&#x201d; OR LLM* OR &#x201c;virtual reality&#x201d; OR VR OR &#x201c;augmented reality&#x201d; OR AR OR &#x201c;mixed reality&#x201d; OR MR OR &#x201c;game-based learning&#x201d; OR gamification OR simulation* OR LMS OR &#x201c;learning management system*&#x201d; OR &#x201c;serious game*&#x201d; OR GeoGebra OR Scratch)</p>
                        <p>AND</p>
                        <p>(&#x201c;learning outcome*&#x201d; OR achievement OR performance OR cognition OR &#x201c;cognitive outcome*&#x201d; OR engagement OR motivation OR satisfaction OR retention OR &#x201c;knowledge acquisition&#x201d; OR &#x201c;academic performance&#x201d; OR &#x201c;student engagement&#x201d;)</p>
                        <p>AND</p>
                        <p>(education OR &#x201c;higher education&#x201d; OR university* OR college* OR school*)</p>
                    </disp-quote>
                </p>
            </sec>
            <sec id="sec9">
                <title>Study selection process</title>
                <p>The screening was conducted around the four stages of the PRISMA model, which are identification, screening, eligibility, and inclusion. The Abstrackr Open Source Digital Software supported by manual searching and organizing was used. There were initially 1,236 records loaded into Abstrackr. After the removal of duplicates using Abstrackr (n&#x00a0;=&#x00a0;186), 1,050 records were screened for title and abstract by using inclusion criteria. After excluding 930 in the screening, 
                    <xref ref-type="fig" rid="f1">Figure 1</xref> depicts that 120 full-text articles were evaluated for eligibility, and 44 full-text articles were excluded during the evaluation of eligibility, 76 (i.e., 50 used for narrative analysis; 26, see 
                    <xref ref-type="table" rid="T2">
Table 2</xref>, used in quantitative analysis) studies fulfilled all the inclusion criteria.</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>
Figure 1. </label>
                    <caption>
                        <title>A PRISMA Flowchart of Systematic Review.</title>
                    </caption>
                    <graphic id="gr1" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/202024/178b4694-d058-4dbe-8e64-760010542462_figure1.gif"/>
                </fig>
            </sec>
            <sec id="sec10">
                <title>Data collection process</title>
                <p>Descriptive and analytical facets of the studies were encoded in a structured manner using an extraction matrix designed in MS Excel (Refer to Extracted Data and Vaiables, 
                    <xref ref-type="bibr" rid="ref29">Geleto et al., 2026</xref>). The following data were extracted from the resources: 1) Study ID; 2) Author/s; 3) Year of publication; 4) Country of the study; 5) Discipline (e.g., Education, Engineering); 6) Technology employed; 7) Design framework (e.g., TPACK, CA); 8) Sample size; 9) Methodology; 10) Outcome type (e.g., performance improvement, skill development, etc); 11) Effect size; 12) Changes in engagement; 13) Challenges; 14) Facilitators; and 15) Notes to the review was added. This systematic coding for a narrative as well as quantitative synthesis ensured comparability.</p>
                <p>The extraction process was done in two ways and 4 steps: 1) Based on the PRISMA Checklist, the 5 authors collected the required information manually from all included resources; 2) The extraction process was also done by NotebookLM Online Open Google Source. During extraction, one resource or article was uploaded into the NotebookLM, Extracted Data and Variables (
                    <xref ref-type="bibr" rid="ref29">Geleto et al., 2026</xref>) and then clear instruction was given to the NotebookLM. Then, NotebookLM extracted the required data accurately article by article; 3) Verification of the extracted data by NotebookLM against those extracted by the authors; and 4) Organization and preparation of the final PRISMA Checklist Filled data.</p>
            </sec>
            <sec id="sec11">
                <title>Data quality and relaibility</title>
                <p>The table presents (Appendix 1) the methodological quality appraisal of 76 studies using the Mixed Methods Appraisal Tool (MMAT), version 2018 developed by Qing N. Hong and colleagues. The MMAT is a critical appraisal framework designed to evaluate the quality of qualitative, quantitative, and mixed-methods studies within systematic reviews.</p>
                <p>The methodological quality appraisal conducted using the MMAT (2018) indicated that the included studies were generally of moderate to high quality. Nearly half of the studies achieved the highest consensus rating, particularly among quantitative and experimental designs, while qualitative and mixed-methods studies more frequently demonstrated moderate methodological rigor. Overall, the appraisal suggests that the evidence base is sufficiently robust to support synthesis and interpretation, although methodological variability across study designs should be considered when interpreting the findings.</p>
                <p>Reviewer agreement and consistency. The inter-rater reliability analysis was conducted using a two-way random-effects model with an absolute agreement definition to examine the consistency among the five reviewers across the rated items. Descriptive statistics indicated that the mean ratings across items were relatively homogeneous, with item means ranging from 2.395 to 2.566 (M = 2.466, SD
                    <sup>2</sup> = .005). The small range of item means (.171) suggests limited variability in the average ratings assigned by the reviewers, indicating a relatively consistent scoring tendency across the five items. Inter-rater agreement was assessed using the intraclass correlation coefficient (ICC). The single-measures ICC demonstrated fair agreement among individual reviewers, ICC(2,1) = .326, 95% CI [.223, .443], F(75, 300) = 3.451, p &lt; .001. This finding indicates that the reliability of ratings from a single reviewer was relatively low to moderate, suggesting some variability in how individual reviewers evaluated the items.</p>
                <p>However, the average-measures ICC, which reflects the reliability of the combined ratings from all five reviewers, indicated good overall agreement, ICC(2,5) = .707, 95% CI [.589, .799], F(75, 300) = 3.451, p &lt; .001. According to commonly accepted benchmarks for ICC interpretation, this value reflects acceptable to good reliability for aggregated ratings. Therefore, while individual reviewer ratings showed only modest consistency, the combined evaluations of the five reviewers produced a substantially more reliable assessment.</p>
            </sec>
            <sec id="sec12">
                <title>Analysis and synthesis methods</title>
                <p>Both quantitatively and qualitatively, in order to answer our first and second research questions '(i.e., How are courses designed with new technologies? How do these technologies influence student learning outcomes and engagement?&#x2019;, the analysis was done: 1) by comparing the design frameworks (e.g., TPACK, CA) against the associated effect sizes and technologies used (see 
                    <xref ref-type="table" rid="T2">
Table 2</xref>). This analysis showed us which design frameworks are associated with which technologies in course development and delivery to bring about high results; 2) The narrative and quantitative description of the relationship between design frameworks and their effects in learning outcomes including engagement was done; and 3) The effect of technology types on learning outcomes including engagement was analyzed in both qualitatively and quantitatively (See 
                    <xref ref-type="table" rid="T3">Table 3</xref>). In order to answer the third review question: &#x2018;Which contextual, institutional and/or pedagogical factors determine success?&#x2019; the data collected from the resources (See Extracted Data and Variables and 
                    <xref ref-type="table" rid="T4">
Table 4</xref>) was used to narrate the challenges and prospects associated to emerging technology integration in course development in higher education.</p>
            </sec>
            <sec id="sec13">
                <title>Overview of included studies</title>
                <p>The review included 76 empirical studies. Other than 76 studies, the rest which are in-text cited and included in the reference list were local policy documents and Ethiopian studies that did not focus on designs and categories of technology. The range of publication years was from 1996 to 2026, with a strong increase in the number of studies in the last 10&#x00a0;years. Review and meta-analytic studies are heterogeneous and comprises of empirical studies, systematic reviews and meta-analyses. In addition to several global systematic reviews and meta-analyses, research was conducted in the United States, the United Kingdom, Turkey, Spain, China, Taiwan, Australia, Indonesia, Malaysia, Saudi Arabia, the United Arab Emirates, Ghana, Nigeria, Oman, Sweden, the Netherlands, France, Finland, Serbia, Cyprus, Pakistan, Canada, Thailand, and South Africa. Most represented regions were Turkey, the United Kingdom, the United States, Spain, and Australia. Disciplines with a specific focus were varied, with education being dominant. Multiple studies examined educator preparation, general education, or higher education contexts, while some looked at discipline-specific contexts (e.g., English language education, mathematics, engineering, computer science, STEM, accounting, sport science, biology, management information systems, social sciences, library and information studies, construction management, and culinary education).</p>
                <p>Commonly studied tools and environments were generative artificial intelligence and large language models (e.g., ChatGPT, GPT-4), VR, AR), MR, mobile learning applications, learning management systems (LMSs), serious games and gamified learning environments, adaptive learning systems, and learning analytics dashboards as well as more general digital and ICT-based teaching tools.</p>
                <p>The included studies were based on a number of different instructional and theoretical models. TPACK was a key framework, especially in studies of teacher development, technology integration and pedagogical competence. CA was commonly adopted in studies on the design of higher education courses and/or programs, and the ADDIE model was frequently cited in studies about designing courses and developing instructions. DBR was evident in work stressing iterative processes and contextual adaptations. Other, less common, frameworks included Game Learning, Adaptive Learning, Design Science Research, and different combinations or hybrids of these.</p>
                <p>The review is methodologically very diverse: quasi-experimental, randomized controlled trials, mixed-methods, case studies, quantitative investigations based on surveys, design and development research, Cochrane literature reviews, and meta-analyses. Sample sizes varied from little qualitative or pilot studies (e.g., 6&#x2013;13 participants) to large-scale survey and multi-cohort interventions; systematic reviews integrates 38&#x2013;150 studies, and meta-analyses pool multiple effect sizes or large numbers of participants (e.g., 1,358 participants included in 11 randomized controlled trials). Typical outcomes included academic achievement, cognitive learning outcomes, motivation, engagement, satisfaction, confidence, technology acceptance, skill acquisition, and teacher professional competence, although a number of studies addressed specialized outcomes such as instructional design competence, development of TPACK, problem solving, computational thinking, situational awareness, knowledge maintenance, learner agency, and quality of academic writing.</p>
            </sec>
        </sec>
        <sec id="sec14" sec-type="results">
            <title>Results</title>
            <sec id="sec15">
                <title>Integration of technologies with design frameworks</title>
                <p>Technology has a lot to offer. One definite advantage of technology in the classroom is that it can be integrated to suit specific needs of any educational style. In this regard, the TPACK model stands out as one of the leading models for supporting such integration, allowing for the harmonization of technology with discipline specific content and pedagogy. Initial implementations of TPACK addressed basic digital technologies such as online instruction and web site design (
                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>), as well as general ICT tools (
                    <xref ref-type="bibr" rid="ref3">Akturk &amp; Ozturk, 2019</xref>). Advanced new technologies widened the focus even further, to include classroom technologies such as smart boards, animations, and simulations (
                    <xref ref-type="bibr" rid="ref2">Akta&#x015f; &amp; &#x00d6;zmen, 2020</xref>). The combination of mobile and social media technologies has also been studied, e.g. 
                    <xref ref-type="bibr" rid="ref52">Maor (2016)</xref> using iPads and Web 2.0 tools such as Socrative and Aurasma, and 
                    <xref ref-type="bibr" rid="ref76">Susilawati et al. (2025)</xref> incorporating the use of TikTok and Zoom in social science teaching.</p>
                <p>In addition, TPACK has been extended to specialized software and programming contexts, for example, in block-based programming environments, such as Scratch (
                    <xref ref-type="bibr" rid="ref11">Atun &amp; Usta, 2019</xref>) and Dynamic mathematics software GeoGebra (
                    <xref ref-type="bibr" rid="ref25">Durdu &amp; Dag, 2017</xref>). In recent years, the framework has been extended to include AI and data analytics, with 
                    <xref ref-type="bibr" rid="ref46">Liu and Zhong (2025)</xref> discussing the integration of generative AI and large language models such as ChatGPT, as well as 
                    <xref ref-type="bibr" rid="ref59">Nantha et al. (2024)</xref> integrating data visualization tools such as Power BI in conjunction with platforms like Canva and Microsoft Teams.</p>
                <p>CA has also been extensively used to describe the alignment of technological tools with intended learning outcomes and/or method of assessment. This model has been especially successful in the convergence of immersive and new technologies. For example, 
                    <xref ref-type="bibr" rid="ref78">Tian and Ironsi (2025)</xref> used AR to support English language learning, while 
                    <xref ref-type="bibr" rid="ref14">Bekar et al. (2024)</xref> applied CA as a pedagogical approach in intricate areas like data science, AI, and machine learning. Similar, to game-based learning methods, CA has been useful in game-based learning (
                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al. (2023)</xref> (
                    <xref ref-type="bibr" rid="ref48">Lopez-Fernandez et al., 2023</xref>) which addresses integration in edu- games (
                    <xref ref-type="bibr" rid="ref40">Kalmpourtzis and Romero, 2020</xref>). Moreover, applications of AI have been brought into alignment to course goals via CA, for instance, 
                    <xref ref-type="bibr" rid="ref64">Pereira et al. (2024)</xref> integrated ChatGPT v.4 in engineering education. Conventional and virtual delivery formats of CA have been applied in the field of portfolios and reflective diaries (
                    <xref ref-type="bibr" rid="ref17">Biggs, 1996</xref>), and case-based learning and flipped classroom approaches (
                    <xref ref-type="bibr" rid="ref83">Yang et al., 2024</xref>).</p>
                <p>The ADDIE model is a series of stages that has been used as a very basic and systematic guide for the development of executable Technology Enhanced Learning (TEL). It covers all the range of technological medium, from mobile to web applications. For instance, 
                    <xref ref-type="bibr" rid="ref65">Prasetyo et al. (2020)</xref> designed an Android mobile learning application, 
                    <xref ref-type="bibr" rid="ref42">KO&#x00c7; (2020)</xref> used web-based applications like bulletin board and mailing system. The model was also successfully implemented in the design of scalable learning environments, such as MOOCs (
                    <xref ref-type="bibr" rid="ref38">Ismail et al., 2018</xref>; 
                    <xref ref-type="bibr" rid="ref12">Balanyk, 2017</xref>). Further, ADDIE has been utilized to inform the creation of digital instructional sequences with tools like Microsoft Office and Canva to design and develop well-organized educational content in the work 
                    <xref ref-type="bibr" rid="ref69">Sada et al. (2025)</xref>.</p>
                <p>Another prominent element is the DBR model, which includes iterative stages of designing, implementation and refining educational practices within the research context. This methodology has been employed in analytics technologies and adaptive technologies, among them. For instance, 
                    <xref ref-type="bibr" rid="ref28">Ford et al. (2017)</xref> carried out iterative evaluation of adaptive learning software. DBR has similarly been instrumental in promoting the adoption of STEM-based innovations such as robotics activities (
                    <xref ref-type="bibr" rid="ref84">Y&#x0131;lmaz, 2025</xref>). In the field of mobile-blended, 
                    <xref ref-type="bibr" rid="ref62">Olawale (2026)</xref> produced mobile-first digital platforms for academic English, and 
                    <xref ref-type="bibr" rid="ref58">Mordacq et al. (2017)</xref> merged blended instruction methods with bio lab instruments such as RNA interference (RNAi).</p>
                <p>Apart from these foundational perspectives, several other theoretical constructs have been brought into play when discussing technology integration in education. Bloom&#x2019;s Taxonomy has also been used for organizing cognitive involvement in TLCs (
                    <xref ref-type="bibr" rid="ref36">Hsu and Chen, 2021</xref>). 
                    <xref ref-type="bibr" rid="ref36">Hsu and Chen (2021)</xref> incorporated virtual reality to test cognitive activities, remembering and analyzing. And for research purposes among user in educational technologies, the Technology Acceptance Model (TAM) has been adapted to examine users&#x2019; decisions to utilize mobile learning (m-learning) via portable handhelds among other technologies (e.g., 
                    <xref ref-type="bibr" rid="ref72">Sarrab et al., 2016</xref>).</p>
            </sec>
            <sec id="sec16">
                <title>Quantitative descriptive synthesis of learning outcomes across design frameworks and technology types</title>
                <p>

                    <bold>Effect size conversion and descriptive aggregation procedures</bold>
                </p>
                <p>To facilitate comparison across studies employing different statistical reporting formats, reported statistics were converted into a common standardized metric, Cohen&#x2019;s d, where sufficient information was available. This procedure was intended to support a descriptive quantitative synthesis rather than a formal meta-analysis.</p>
                <p>Inclusion Criteria for Effect Size Conversion. Studies were included in the quantitative synthesis when they met the following criteria: 1) employed quantitative or mixed-methods designs; 2) reported a directly interpretable effect size or a convertible statistical value (e.g., t, &#x03b7;
                    <sup>2</sup>, &#x03c9;
                    <sup>2</sup>, or R
                    <sup>2</sup>); 3) evaluated learning-related outcomes; and 4) explicitly identified the instructional design framework or pedagogical model used. Because substantial methodological heterogeneity existed across studies including differences in intervention duration, outcome measures, technologies, and research designs, effect sizes were descriptively aggregated using arithmetic means rather than inverse-variance weighted meta-analytic procedures.</p>
                <p>The following conversion formulas were used to standardize reported statistics into Cohen&#x2019;s d:
                    <list list-type="alpha-upper">
                        <list-item>
                            <label>A.</label>
                            <p>

                                <bold>&#x03b7;</bold>
                                <sup>

                                    <bold>2</bold>
                                </sup> 
                                <bold>or Partial &#x03b7;</bold>
                                <sup>

                                    <bold>2</bold>
                                </sup> 
                                <bold>to Cohen&#x2019;s d</bold>
                            </p>
                            <p>

                                <disp-formula id="e41">

                                    <mml:math display="inline">
                                        <mml:mi mathvariant="normal">d</mml:mi>
                                        <mml:mo>=</mml:mo>
                                        <mml:mn>2</mml:mn>
                                        <mml:mo>&#x221a;</mml:mo>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:msup>
                                                <mml:mi mathvariant="normal">&#x03b7;</mml:mi>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>/</mml:mo>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mn>1</mml:mn>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:msup>
                                                    <mml:mi mathvariant="normal">&#x03b7;</mml:mi>
                                                    <mml:mn>2</mml:mn>
                                                </mml:msup>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:math>
</disp-formula>
                            </p>
                        </list-item>
                        <list-item>
                            <label>B.</label>
                            <p>

                                <bold>&#x03c9;</bold>
                                <sup>

                                    <bold>2</bold>
                                </sup> 
                                <bold>to Cohen&#x2019;s d</bold>

                                <disp-formula id="e1">

                                    <mml:math display="block">
                                        <mml:mi mathvariant="normal">d</mml:mi>
                                        <mml:mo>=</mml:mo>
                                        <mml:mn>2</mml:mn>
                                        <mml:mo>&#x221a;</mml:mo>
                                        <mml:mrow>
                                            <mml:mo stretchy="true">(</mml:mo>
                                            <mml:msup>
                                                <mml:mi mathvariant="normal">&#x03c9;</mml:mi>
                                                <mml:mn>2</mml:mn>
                                            </mml:msup>
                                            <mml:mo>/</mml:mo>
                                            <mml:mrow>
                                                <mml:mo stretchy="true">(</mml:mo>
                                                <mml:mn>1</mml:mn>
                                                <mml:mo>&#x2212;</mml:mo>
                                                <mml:msup>
                                                    <mml:mi mathvariant="normal">&#x03c9;</mml:mi>
                                                    <mml:mn>2</mml:mn>
                                                </mml:msup>
                                                <mml:mo stretchy="true">)</mml:mo>
                                            </mml:mrow>
                                            <mml:mo stretchy="true">)</mml:mo>
                                        </mml:mrow>
                                    </mml:math>
</disp-formula>
                            </p>
                        </list-item>
                    </list>

                    <list list-type="alpha-upper">
                        <list-item>
                            <label>C.</label>
                            <p>

                                <bold>Mean Effect Size When Multiple Effects Exist Within One Study</bold>
                            </p>
                        </list-item>
                    </list>

                    <disp-formula id="e2">

                        <mml:math display="block">
                            <mml:msup>
                                <mml:mi mathvariant="normal">d</mml:mi>
                                <mml:mo>-</mml:mo>
                            </mml:msup>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi mathvariant="normal">&#x03a3;</mml:mi>
                                <mml:mspace width="0.25em"/>
                                <mml:msub>
                                    <mml:mi mathvariant="normal">d</mml:mi>
                                    <mml:mi mathvariant="normal">i</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mi mathvariant="normal">k</mml:mi>
                        </mml:math>
</disp-formula>
                </p>
                <p>Where: d
                    <sub>i</sub>:&#x00a0;=&#x00a0;an effect size from the study; and k&#x00a0;=&#x00a0;number of effect sizes in the study.
                    <list list-type="alpha-upper">
                        <list-item>
                            <label>D.</label>
                            <p>

                                <bold>t-statistic to Cohen&#x2019;s d</bold>
                            </p>
                        </list-item>
                    </list>

                    <disp-formula id="e3">

                        <mml:math display="block">
                            <mml:mi mathvariant="normal">d</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mtext>2t</mml:mtext>
                            <mml:mo>/</mml:mo>
                            <mml:mo>&#x221a;</mml:mo>
                            <mml:mi>df</mml:mi>
                        </mml:math>
</disp-formula>

                    <list list-type="alpha-upper">
                        <list-item>
                            <label>E.</label>
                            <p>

                                <bold>R</bold>
                                <sup>

                                    <bold>2</bold>
                                </sup> 
                                <bold>to Cohen&#x2019;s d</bold>
                            </p>
                        </list-item>
                    </list>

                    <disp-formula id="e4">

                        <mml:math display="block">
                            <mml:mi mathvariant="normal">d</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mn>2</mml:mn>
                            <mml:mo>&#x221a;</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:msup>
                                    <mml:mi mathvariant="normal">R</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mo>&#x221a;</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:msup>
                                    <mml:mi mathvariant="normal">R</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>=</mml:mo>
                            <mml:mtext>2r</mml:mtext>
                            <mml:mo>/</mml:mo>
                            <mml:mo>&#x221a;</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>1</mml:mn>
                                <mml:mo>&#x2212;</mml:mo>
                                <mml:msup>
                                    <mml:mi mathvariant="normal">r</mml:mi>
                                    <mml:mn>2</mml:mn>
                                </mml:msup>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                        </mml:math>
</disp-formula>

                    <list list-type="alpha-upper">
                        <list-item>
                            <label>F.</label>
                            <p>

                                <bold>Mean standardized effect estimate</bold>
                            </p>
                            <p>When multiple effect sizes were reported within a single study, an unweighted arithmetic mean was calculated to produce a single representative estimate for descriptive comparison purposes:</p>
                        </list-item>
                    </list>

                    <disp-formula id="e5">

                        <mml:math display="block">
                            <mml:msup>
                                <mml:mi mathvariant="normal">d</mml:mi>
                                <mml:mo>-</mml:mo>
                            </mml:msup>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mi mathvariant="normal">&#x03a3;</mml:mi>
                                <mml:mspace width="0.25em"/>
                                <mml:msub>
                                    <mml:mi mathvariant="normal">d</mml:mi>
                                    <mml:mi mathvariant="normal">i</mml:mi>
                                </mml:msub>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mi mathvariant="normal">k</mml:mi>
                        </mml:math>
</disp-formula>
</p>
                <p>Where: d
                    <sub>i</sub>&#x00a0;=&#x00a0;effect size from a study; and k&#x00a0;=&#x00a0;number of included studies.</p>
                <p>Because the included studies varied considerably in methodological characteristics and sufficient variance information was not consistently available, no weighted meta-analytic modeling, heterogeneity analysis, publication bias assessment, or confidence interval estimation was conducted. Consequently, the quantitative findings should be interpreted as indicative descriptive trends rather than definitive causal estimates.</p>
            </sec>
            <sec id="sec17">
                <title>Design frameworks and their learning outcome effect sizes</title>
                <p>Assessments of instructional design models in technology-based learning environments have increasingly utilized descriptive quantitative synthesis techniques to assess the relative effectiveness of such models in enhancing learning outcomes. Effect sizes offer a consistent way to report and compare results of diverse studies, and facilitate detection of patterns in instructional effectiveness regardless of sample size or type of outcome measure (
                    <xref ref-type="bibr" rid="ref21">Cohen, 2013</xref>). Here, we investigate how large improvements in learning outcomes associated with these frameworks by transforming various statistical measures used in the literature into a single metric, the Cohen&#x2019;s d. The primary aim was to investigate the relative potency of instructional design models in producing empirically demonstrable learning gains, and to explore the technological and disciplinary domains within which they may be best suited.</p>
            </sec>
            <sec id="sec18">
                <title>Effect sizes across design frameworks</title>
                <p>
                    <xref ref-type="table" rid="T1">
Table 1</xref> presents the individual study effect size and mean for each of the frameworks of interest. The TPACK framework had a aggregated effect estimate of d = 0.65, showing a moderate to large effect on learning. Study effect sizes ranged from small (d = 0.06) to large (d = 0.97). CA was associated with a mean standardized effect estimate d of 0.74 which represents a moderate to large effect in educational intervention and reveals that the degree of alignment of intended learning outcomes, teaching and learning activities and assessment procedures strengthens the efficacy of instruction. Similarly, the ADDIE-based model produced a mean standardized effect estimate of d = 0.66, indicating stable moderate to large gains in learning. DBR was associated with a mean standardized effect estimate of d = 0.68, indicating positive learning outcomes association with iterative instructional design and refinement; although a smaller number of studies could be included for this framework. Hybrid or integrated models resulted in an effect size of d = 0.43, a moderate effect, yet this is a comparatively moderate value. The mean standardized effect estimate from game-based learning applications was d = 0.66 across knowledge acquisition, learner confidence, and performance outcomes, showing that interactive and immersive learning environments may promote engagement and cognitive processing. In contrast, the Deep Learning model showed the largest mean standardized effect estimate (d = 1.30), representing a very large educational effect. The effect sizes in these studies ranged from d = 0.68 to d = 1.92, indicating a high degree of learning enhancement.</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Design frameworks, studies and their corresponding effect sizes.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Design Framework</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Study</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Metric</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Converted Effect Size(d)</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="11" valign="top">
                                    <italic toggle="yes">TRACK</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.83</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.73</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.06</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.75</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">SMD</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.73</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref3">Akturk &amp; Ozturk (2019)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">R
                                    <sup>2</sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.37</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref54">Mero&#x00f1;o et al. (2021)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x03b7;
                                    <sup>2</sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.97</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref11">Atun and Usta (2019)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">t</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.83</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref76">Susilawati et al. (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">gain difference</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.64</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref51">Lyublinskaya and Tournaki (2011)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">&#x03c9;
                                    <sup>2</sup>&#x00a0;=&#x00a0;0.074</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.57</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d mean</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>.65</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="5" valign="top">
                                    <italic toggle="yes">Constructive Alignment</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al. (2023)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.75</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref78">Tian &amp; Ironsi (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>t</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1.12</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref85">Zhang et al. (2022)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.51</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref79">Treleaven and Voola (2008)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mean Difference</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.56</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d mean</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>.74</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="6" valign="top">
                                    <italic toggle="yes">ADDIE</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref75">Sial et al. (2024)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.58</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref65">Prasetyo et al. (2020)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.66</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref26">Feng and Sangsawang (2023)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.73</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref8">Ali and Maliki (2024)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.61</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref53">Mdodana-Zide (2024)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.71</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>.66</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="3" valign="top">
                                    <italic toggle="yes">Design-based Research</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref62">Olawale (2026)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.68</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref84">Y&#x0131;lmaz (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">t</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.67</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td colspan="1" rowspan="1"/>
                                <td align="left" colspan="1" rowspan="1" valign="top">.68</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="5" valign="top">
                                    <italic toggle="yes">Hybrid</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref6">Alhazzaa &amp; Yan (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.30</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref33">Han et al. (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.52</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref22">Cromley et al. (2023)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.33</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref77">Tamim et al. (2011)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.35</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d mean</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>.43</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="4" valign="top">
                                    <italic toggle="yes">Game-based learning</italic>
</td>
                                <td align="left" colspan="1" rowspan="3" valign="top">
                                    <xref ref-type="bibr" rid="ref43">Lee et al. (2024)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Knowledge: g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.75</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Confidence: g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.73</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Performance: g</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.49</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d mean</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>.66</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="2" valign="top">
                                    <italic toggle="yes">Deep Learning</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref81">Wang et al. (2025)</xref>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">D range</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">.68&#x2013;1.92</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>mean standardized effect estimate</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>d mean</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>1.3</bold>
</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>

                            <italic toggle="yes">Note</italic>: For D Range, Mean Effect was calculated as: (.68&#x00a0;+&#x00a0;1.92)/2&#x00a0;=&#x00a0;1.3</p>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table 2. </label>
                    <caption>
                        <title>Design frameworks and mean standardized effect estimates by their dominant technology types.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Design Framework</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Empirical studies with usable numeric effect sizes (Quantitative/mixed methods)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Mean standardized effect estimate (Standardized or Equivalent)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Dominant technologies implemented</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Dominant disciplines</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">TPACK</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">10</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">0.65 (Moderate to Large)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">LMS, ICT tools, e-learning platforms, digital collaboration tools</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Education, STEM, Mathematics</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Constructive alignment (CA)</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">0.74 (Moderate&#x2013;Large)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Game-based learning, flipped classroom, simulation</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Engineering, Computer Science, Education</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">ADDIE</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">0.66 (Moderate&#x2013;Large)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Online learning systems, instructional modules, mobile learning</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Education, Language learning</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Design-based research (DBR)</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">0.68 (Moderate&#x2013;Large)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Adaptive learning systems, blended learning environments</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Education, Biology</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Hybrid/Integrated frameworks</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">0.43 (Moderate)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Virtual reality, AR/VR, learning analytics</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Engineering, Education</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Deep learning</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="char" char="(" colspan="1" rowspan="1" valign="top">1.30 (Very Large)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mixed Reality + AI systems</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Engineering</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>

                            <italic toggle="yes">

                                <bold>Note</bold>.</italic> Cohen&#x2019;s 
                            <italic toggle="yes">d</italic> values were interpreted as follows: 
                            <italic toggle="yes">d</italic>&#x00a0;&#x2264;&#x00a0;.20 (small), .20&#x00a0;&lt;&#x00a0;
                            <italic toggle="yes">d</italic>&#x00a0;&lt;&#x00a0;.50 (moderate), .50&#x00a0;&#x2264;&#x00a0;
                            <italic toggle="yes">d</italic>&#x00a0;&lt;&#x00a0;.80 (moderate to large), .80&#x00a0;&#x2264;&#x00a0;
                            <italic toggle="yes">d</italic>&#x00a0;&lt;&#x00a0;1.20 (large), and 
                            <italic toggle="yes">d</italic>&#x00a0;&#x2265;&#x00a0;1.20 (very large) (Cohen, 1988).</p>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Summary of quantitative results by technology type.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Technology type</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Mean standardized effect estimate (Learning Outcomes)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Engagement change (Indicative Trend)</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Common metrics</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Evidence strength</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">AR /VR/MR (Immersive Technologies)</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g&#x00a0;=&#x00a0;0.98</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">+20 to +30 (qualitative and behavioral indicators)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Knowledge tests; skill acquisition; recall/performance; retention; motivation and presence scales</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">High</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">AI /Generative AI/Learning Analytics</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g&#x00a0;=&#x00a0;.62</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">+18 to +25 (motivation, cognition, usage analytics)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Cognitive performance scores; engagement dashboards; progression analytics; perception surveys</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Medium to High</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Game-Based Learning/Serious Games</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">g&#x00a0;=&#x00a0;.71</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">+17 to +24 (motivation, usability, satisfaction)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Knowledge gains; confidence scales; usability; gameplay analytics</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Medium to High</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Mobile/M-Learning/Ubiquitous Learning</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">NR (no directly comparable standardized effect size reported)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">+14 to +20 (usage frequency, motivation, self-efficacy)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Survey scales; achievement scores; system usage logs; intention-to-use indicators</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Medium</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Adaptive/Personalized Learning Systems</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">d&#x00a0;=&#x00a0;.65</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">+16 to +22 (sustained performance and engagement)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Mastery progression; adaptive pathway analytics; performance maintenance indicators</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Medium to High</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <p>

                            <bold>Note.</bold> Effect sizes are summarized from the included studies. NR&#x00a0;=&#x00a0;not reported or not directly comparable. Engagement change reflects indicative trends reported in the studies and is not a pooled meta-analytic estimate.</p>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="T4" orientation="portrait" position="float">
                    <label>
Table 4. </label>
                    <caption>
                        <title>Typical challenges and enablers in course development in the application of new technologies.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Category of challenges</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Major challenges</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Facilitators/enablers</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Representative sources</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Institutional/infrastructure</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Low internet bandwidth and an unstable internet connection; power outages and a lack of backup generators; high expenses for hardware and HMDs; disparities in device ownership (PC vs smartphone); environmental restrictions to VR/AR sessions (temperature, noise); scarce adoption in classrooms under real conditions</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Planning and investment in institutional ICT; infrastructure resilience and standby power; procurement of accessible devices (mobile-first options); technical support teams; integration with existing LMSs and institutional platforms; controlled lab environments for immersive tech</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref6">Alhazzaa &amp; Yan, 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref66">Radianti et al., 2020</xref>; 
                                    <xref ref-type="bibr" rid="ref49">Loughlin et al., 2021</xref>; 
                                    <xref ref-type="bibr" rid="ref72">Sarrab et al., 2016</xref>; 
                                    <xref ref-type="bibr" rid="ref4">Alfauzan &amp; Tarchouna, 2017</xref>; 
                                    <xref ref-type="bibr" rid="ref17">Biggs, 1996</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Pedagogical/instructional design</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Poor integration of learning design (e.g., CA) within technology-based course design; course design fragmentation; emphasis on usability/novelty rather than directly measurable learning outcomes; uncertain alignment of TLAs with ILOs; brief interventions constraining the depth of instruction.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Application of teaching/design models (e.g. TPACK, CA, ADDIE); incremental and repeated course development; real-world problem-solving activities; clear mapping of ILOs&#x2013;TLAs&#x2013;assessment; cycles of formative feedback</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">(
                                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>); 
                                    <xref ref-type="bibr" rid="ref64">Pereira, et al., 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref52">Maor, 2016</xref>; 
                                    <xref ref-type="bibr" rid="ref42">Ko&#x00e7;, 2020</xref>; 
                                    <xref ref-type="bibr" rid="ref24">Dilaines et a., 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref12">Balanyk, 2017</xref>; 
                                    <xref ref-type="bibr" rid="ref35">Hristov et al. 2023</xref>; 
                                    <xref ref-type="bibr" rid="ref7">Ali, 2018</xref>; 
                                    <xref ref-type="bibr" rid="ref69">Sada et al., 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref32">Hall, 2020</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Faculty readiness/professional capacity</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Poor digital pedagogy knowledge and TPACK development in some contexts; resistance to use; fear of failure/embarrassment; heavy workload and lack of time for designing; inconsistent instructor modeling</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Continuous professional development (12&#x00a0;week professional development examples); reflective practice and micro-teaching; peer collaboration, mentoring, faculty mentor programs; researcher/facilitator modeling; discipline-based support teams.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref25">Durdu &amp; Dag, 2017</xref>; 
                                    <xref ref-type="bibr" rid="ref60">Njuguna, 2020</xref>; 
                                    <xref ref-type="bibr" rid="ref53">Mdodana-Zide, 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref15">Bergroth-Koskinen &amp; Sepp&#x00e4;l&#x00e4; 2012</xref>; 
                                    <xref ref-type="bibr" rid="ref69">Sada et al., 2025</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Student readiness/cognitive &amp; technical factors</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Gaps in digital literacy; uneven prior knowledge; cognitive overload due to dense or ill-organized multimodal content; novelty effects; differences among devices affecting user experience, e.g., headset occlusion reduces accuracy of facial expressions.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Orientation programs and onboarding; modular/sequenced content to reduce cognitive load; adaptive learning and personalized pathways; scaffolding and step-by-step feedback; mobile-friendly design</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref20">Christodoulou &amp; Angeli, 2022</xref>; 
                                    <xref ref-type="bibr" rid="ref77">Tamim et al., 2011</xref>; 
                                    <xref ref-type="bibr" rid="ref47">Liu et al., 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref37">Ibrahim et al., 2018</xref>; 
                                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>; 
                                    <xref ref-type="bibr" rid="ref39">Johnson et al., 2017</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Technology &amp; system design</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Timing and computational capacity limitations; limited tactile/haptic realism; usability constraints and low reliability in certain prototypes; model precision limitations for adaptive systems; limited multimodal sensing fidelity</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">User-centered and participatory design; multimodal interaction and sensing; real-time feedback and adaptive guidance; iterative usability testing and longitudinal follow-up.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref81">Wang et al., 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref33">Han et al., 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref85">Zhang et al., 2022</xref>; 
                                    <xref ref-type="bibr" rid="ref17">Biggs 1996</xref>; 
                                    <xref ref-type="bibr" rid="ref79">Treleaven &amp; Voola, 2008</xref>; 
                                    <xref ref-type="bibr" rid="ref58">Mordacq, et al., 2017</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Evaluation &amp; evidence generation</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Short-term studies are predominant; great heterogeneity is observed in study designs and MEs; self-report and Level 1&#x2013;2 outcomes are the most used; and few measures for longitudinal or behavioral (Level 3&#x2013;4) assessment are available.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Combination of qualitative and quantitative methods (i.e., mixed-method evaluations), use of experimental designs and longitudinal designs; application of learning analytics and triangulation with performance data; use of larger sample sizes and standardized metrics.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref5">Alfredo et al., 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref28">Ford et al., 2017</xref>; Angel</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Ethical, privacy &amp; trust issues</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Data privacy and consent issues; bias in algorithms and limits on transparency in GenAI/LA tools; risk of over-reliance on AI-generated insights; execution lag in governance.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Human-centered design; ethical governance frameworks; transparency/explainability mechanisms; stakeholder involvement and trainer supervision; clear data policies.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref70">Sajja et al., 2025</xref>; 
                                    <xref ref-type="bibr" rid="ref4">Alfauzan &amp; Tarchouna, 2017</xref>; 
                                    <xref ref-type="bibr" rid="ref52">Maor, 2016</xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <italic toggle="yes">Contextual &amp; socioeconomic factors</italic>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">The following were barriers encountered:1) SES bias in device availability and access to the internet; 2) differences in patterns of technology use across geographical location; 3) a relatively small number of real classrooms using this technology; and 4) contextual delimitations (e.g., home-based delivery due to COVID-19).</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Utilization in mobile devices and low bandwidth; delivery modalities (blended/hybrid); contextualization to local learner; community/institution partnership and focused funding.</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <xref ref-type="bibr" rid="ref72">Sarrab et al., 2016</xref>; 
                                    <xref ref-type="bibr" rid="ref50">Lutfi et al., 2022</xref>; 
                                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref8">Ali &amp; Maliki, 2024</xref>; 
                                    <xref ref-type="bibr" rid="ref39">Johnson et al., 2017</xref>
                                </td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec id="sec19">
                <title>Effects of design frameworks on learning outcomes and engagement: mixed results</title>
                <p>

                    <bold>Cognitive results</bold>. Meta-analytic and experimental findings showed moderate to large cognitive benefits when frameworks were used to develop the pedagogy (g&#x00a0;=&#x00a0;0.729 cognitive; learning gains overall g&#x00a0;=&#x00a0;0.75; 
                    <xref ref-type="bibr" rid="ref77">Tamim et al., 2011</xref>, 
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>, 
                    <xref ref-type="bibr" rid="ref11">Atun and Usta, 2019</xref>, 
                    <xref ref-type="bibr" rid="ref79">Treleaven and Voola, 2008</xref>). Post-test increases are noted in individual studies (e.g., a number of quasi-experimental studies with significance testing using t or ANOVA; 
                    <xref ref-type="bibr" rid="ref47">Liu et al., 2025</xref>, 
                    <xref ref-type="bibr" rid="ref36">Hsu and Chen, 2021</xref>, 
                    <xref ref-type="bibr" rid="ref37">Ibrahim et al., 2018</xref>).</p>
                <p>

                    <bold>Affective engagement and motivation</bold>. Positive affective impacts (motivation, satisfaction) are typical in reports of game-based, AR/VR, and adaptive platforms (Hedges g&#x00a0;=&#x00a0;0.729; 
                    <xref ref-type="bibr" rid="ref19">Calik &amp; Kapucu, 2022</xref>; 
                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>; 
                    <xref ref-type="bibr" rid="ref45">Ling &amp; Chiang, 2022</xref>). Novelty effects are identified as a potential confound (
                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>).</p>
                <p>

                    <bold>Behavioral results and longer-term transfer</bold>. Behavioral (e.g., sustained behavior change, classroom participation) outcomes are reported inconsistently and less frequently; effect sizes are typically small or are not provided (behavioral Hedges g&#x00a0;=&#x00a0;0.057; 
                    <xref ref-type="bibr" rid="ref11">Atun and Usta, 2019</xref>; 
                    <xref ref-type="bibr" rid="ref9">Angel, 2021</xref>; 
                    <xref ref-type="bibr" rid="ref80">Tu et al., 2021</xref>). There is a significant lack of longitudinal and Level 3&#x2013;4 results (
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>).</p>
                <p>

                    <bold>Moderators</bold>. Sample size, length of intervention (&gt;2&#x00a0;weeks tend to demonstrate larger knowledge effects), type of technology (AR usually reduces cognitive load compared with immersive HMD VR; 
                    <xref ref-type="bibr" rid="ref49">Loughlin et al., 2021</xref>), prior knowledge of the learner (expertise-reversal effects; partial &#x03b7;
                    <sup>2</sup> results), socio-economic/access related issues, and fidelity of pedagogical integration are all reported to be influential factors (
                    <xref ref-type="bibr" rid="ref25">Durdu and Dag, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref49">Loughlin et al. 2021</xref>, 
                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>).</p>
                <p>

                    <bold>Mechanisms and design features related to positive effects.</bold> Explicit alignment of learning objectives-activities-assessments (CA), scaffolding/adaptive guidance, immediate feedback, multimodal interaction, authentic problem solving, and teacher professional development to support framework implementation have been consistently identified as enablers (
                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>; 
                    <xref ref-type="bibr" rid="ref40">Kalmpourtzis and Romero, 2020</xref>; 
                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al., 2023</xref>; 
                    <xref ref-type="bibr" rid="ref85">Zhang et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref28">Ford et al., 2017</xref>).</p>
            </sec>
            <sec id="sec20">
                <title>Technology types and their effects on student learning outcomes and engagement: quantitative results</title>
                <p>A descriptive quantitative synthesis of the included studies shows that the size of the effects on student learning outcomes and engagement differ by technology type. In general, the effects of immersive, intelligent and adaptive technologies on cognitive performance and learner participation are more pronounced and consistent than those of more traditional digital delivery platforms.</p>
                <p>

                    <bold>AR /VR/MR</bold>
                </p>
                <p>Extracted standardized learning-outcome effect sizes from the relevant studies: SR19 (1.13), SR26 (1.92), SR20 (0.52), SR21 (0.33)
                    <disp-formula id="e6">

                        <mml:math display="block">
                            <mml:mtext>Mean</mml:mtext>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>1.13</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>1.92</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.52</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.33</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mn>4</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.8635</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.98</mml:mn>
                        </mml:math>
</disp-formula>
                </p>
                <p>

                    <bold>AI /generative AI/learning analytics</bold>
                </p>
                <p>Extracted standardized effect sizes: SR02(0.831), SR03(0.729), SR04(0.057), SR05(0.752), SR06(0.729)
                    <disp-formula id="e7">

                        <mml:math display="block">
                            <mml:mtext>Mean</mml:mtext>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>0.831</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.729</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.057</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.752</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.729</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mn>5</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.6196</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.620</mml:mn>
                        </mml:math>
</disp-formula>
                </p>
                <p>

                    <bold>Game-based learning/serious games</bold>
                </p>
                <p>Extracted standardized effect sizes: SR13 (Mean = 0.75), SR18 (Mean = 0.66)
                    <disp-formula id="e8">

                        <mml:math display="block">
                            <mml:mtext>Mean</mml:mtext>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>0.75</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>0.66</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mn>2</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>0.71</mml:mn>
                        </mml:math>
</disp-formula>
                </p>
                <p>

                    <bold>Mobile/m-learning/ubiquitous learning</bold>
                </p>
                <p>No directly comparable standardized effect size was reported in the workbook for the mobile studies. So we reported this as NR and summarized the quantitative gains descriptively instead</p>
                <p>

                    <bold>Adaptive/personalized learning systems</bold>
                </p>
                <p>Extracted partial &#x03b7;
                    <sup>2</sup> values: SR07 (&#x03b7;
                    <sup>2</sup> = 0.06, &#x03b7;
                    <sup>2</sup> = 0.12) converted to (d = .52; d = .79)
                    <disp-formula id="e9">

                        <mml:math display="block">
                            <mml:mtext>Mean</mml:mtext>
                            <mml:mspace width="0.25em"/>
                            <mml:mi mathvariant="normal">d</mml:mi>
                            <mml:mo>=</mml:mo>
                            <mml:mrow>
                                <mml:mo stretchy="true">(</mml:mo>
                                <mml:mn>.52</mml:mn>
                                <mml:mo>+</mml:mo>
                                <mml:mn>.79</mml:mn>
                                <mml:mo stretchy="true">)</mml:mo>
                            </mml:mrow>
                            <mml:mo>/</mml:mo>
                            <mml:mn>2</mml:mn>
                            <mml:mo>=</mml:mo>
                            <mml:mn>.65</mml:mn>
                        </mml:math>
</disp-formula>
                </p>
                <p>As shown in 
                    <xref ref-type="table" rid="T3">
Table 3</xref>, technologies, such as AR, VR, and MR had the greatest overall effect on learning results with an average effect size of g&#x00a0;=&#x00a0;0.98, which implies that it has a significant educational impact. Studies frequently indicated enhancements in knowledge retention, procedural skill acquisition, and conceptual understanding, especially in simulation-based and experiential learning scenarios. Engagement results followed a similar pattern with tentative improvements of about 20&#x2013;30% for both qualitative and behavioral indicators such as time-on-task, perceived presence and motivation for learners.</p>
                <p>Generative AI, LA systems, and AI had a medium-to-large mean standardized effect estimate (g&#x00a0;=&#x00a0;0.62) on learning outcomes, indicating significant improvements in cognitive performance and academic success. Positive changes in engagement were also significant, with rises in sustained attention, system interaction frequency, and self-regulated learning behaviors of roughly 18% to 25%. Real-time feedback, automated scaffolding, and data-driven instruction adaptation were many studies credited these results to. The quality of evidence for AI-based solutions was generally high, particularly for those in higher education and blended learning, given that analytics dashboards and adaptive feedback mechanisms are often integrated into course materials.</p>
                <p>Game-based learning and serious games produced a moderate to large mean standardized effect estimate (g&#x00a0;=&#x00a0;0.71), showing significant gains in knowledge and learner confidence. The increases in engagement were about 17&#x2013;24% of the original values, mostly in terms of motivation, usability scores, and persistence on the task. These technologies seem to capitalize on innate motivational systems such as challenge, competition, and reward structures, which are consistent with self-determination theory and gamification models recognized in the field of educational psychology. While the evidence for game-based learning was strong, inconsistencies in the design of games and alignment with instruction led to slightly less convergence when compared to immersive and AI-based systems.</p>
                <p>Mobile learning (m-learning) and ubiquitous learning environments also reflected positive trends for engagement, although no directly comparable mean standardized effect estimate values were applicable. The percentage improvements in engagement were from about 14% to 20%, as measured in incident of use, self-efficacy, and learner satisfaction questionnaires among others. Metrics that measure learning outcomes, such as scores obtained or rates of completion, showed modest positive effects, and thus the overall strength of evidence for mobile learning was rated as moderate.</p>
                <p>Adaptive and personalized learning systems were found to have a moderate-to-high effect on learning outcomes, with a reported standardized mean difference of d&#x00a0;=&#x00a0;0.65. These systems were identified with sustained and improved rates of mastery over time. Engagement enhancements ranged from 16% to 22%, specifically in persistence, task completion, and individual learning path utilization and test performance.</p>
            </sec>
            <sec id="sec21">
                <title>Technology types and their effects on learning outcomes and engagement: mixed results</title>
                <p>This review integrates the impact of various technology kinds on learning results and student engagement in different educational contexts. On the whole, the most compelling evidence for positive outcomes in the data set was found for generative AI, serious games, MR, AR, and certain adaptive learning systems, particularly for cognitive and affective learning outcomes. Generative AI had significant cognitive and moderate affective improvements, but little change in behavior, indicating that higher learning and motivation levels do not necessarily lead to sustained behavioral changes (
                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong, 2025</xref>; 
                    <xref ref-type="bibr" rid="ref67">Rodr&#x00ed;guez-Ortiz et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref14">Bekar et al., 2024</xref>). The effects of immersive technologies, such as VR, AR and MR were generally moderate to strong on knowledge, attention, immersion and skill acquisition, but they were influenced by the quality of the design, the expertise of learners and implementation conditions (
                    <xref ref-type="bibr" rid="ref33">Han et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref37">Ibrahim et al., 2018</xref>; 
                    <xref ref-type="bibr" rid="ref81">Wang et al., 2025</xref>). Game-based learning also demonstrated fairly consistent positive effects on knowledge, confidence, and engagement particularly when integrated with curriculum objectives and effectively supported through feedback (
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al., 2023</xref>).</p>
                <p>Engagement gains were common throughout the data set of course, but the measurement of long-term behavioral effects was scarcer. Recurring facilitators were scaffolding, authentic tasks, feedback, collaboration, and alignment of technology, pedagogy and content, and recurring barriers were access issues, brief intervention period, novelty effects, cognitive load, and lack of support for teachers. The review states that technology works best when integrated within robust pedagogical design frameworks as opposed to being adopted as a stand-alone
 tool.</p>
                <p>

                    <bold>Engagement results by technology type.</bold> A particularly clear trend in the data is that engagement appears to increase across a number of technology types, even when effects on achievement are smaller and/or less consistent. Positive results of engagement were reported for generative AI,VR/AR/MR, serious games, mobile learning, LMS environments, and blended or online approaches (
                    <xref ref-type="bibr" rid="ref66">Radianti et al., 2020</xref>; 
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref59">Nantha et al., 2024</xref>). In immersive settings, engagement was frequently equated with increased attention, concentration, presence, and enjoyment (
                    <xref ref-type="bibr" rid="ref37">Ibrahim et al., 2018</xref>; 
                    <xref ref-type="bibr" rid="ref47">Liu et al., 2025</xref>). In game-based situations, engagement manifested itself as active involvement, interactivity, confidence and liking for the teaching format (
                    <xref ref-type="bibr" rid="ref48">L&#x00f3;pez-Fern&#x00e1;ndez et al., 2023</xref>; 
                    <xref ref-type="bibr" rid="ref74">Sharmin et al., 2024</xref>). Engagement, in particular, manifested as enhanced interaction, convenience and satisfaction (
                    <xref ref-type="bibr" rid="ref41">Kaya &amp; Adiguzel, 2021</xref>).</p>
                <p>At the same time, the data indicate that engagement was often assessed qualitatively or via self-report rather than via validated behavioral indicators of long-term engagement. This limitation is particularly pronounced in the generative AI meta-analysis which reveals strong cognitive and affective effects, but surprisingly small behavior change (
                    <xref ref-type="bibr" rid="ref46">Liu &amp; Zhong, 2025</xref>; 
                    <xref ref-type="bibr" rid="ref44">Li et al., 2025</xref>). A homologous problem arises in serious game and VR research, where short-term motivation and attention are common measures, but enduring behavioral change and long-term transfer are infrequently addressed (
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref66">Radianti et al., 2020</xref>). Thus, the review shows that technology consistently leads to higher engagement, yet there is a need in the field for more robust measures of sustained participation, transfer, and longer term behavioral outcomes.</p>
            </sec>
            <sec id="sec22">
                <title>Challenges and facilitators in implementation</title>
                <p>The synthesis revealed common structural and pedagogical challenges and critical facilitators that predicted positive course development outcomes (see 
                    <xref ref-type="table" rid="T4">
Table 4</xref>).</p>
                <p>Challenges at the level of the institution as whole, pedagogy, educators and students, and the technical, evaluative, ethical, and contextual dimensions are now becoming apparent as immersive and cutting-edge educational technology are being rapidly incorporated into higher education. Commonly reported institutional and infrastructure challenges are lack of sufficient internet bandwidth, power outages, high cost of hardware and HMD, disparity in the types of devices owned by students (PC or smartphones), and environmental limitations in conducting VR/AR sessions in real classrooms (temperature, noise), which hinder real-world classroom application (
                    <xref ref-type="bibr" rid="ref6">Alhazza &amp; Yan, 2025</xref>; 
                    <xref ref-type="bibr" rid="ref66">Radianti et al., 2020</xref>; 
                    <xref ref-type="bibr" rid="ref49">Loughlin et al., 2021</xref>; 
                    <xref ref-type="bibr" rid="ref72">Sarrab et al., 2016</xref>; 
                    <xref ref-type="bibr" rid="ref4">Alfauzan &amp; Tarchouna, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref17">Biggs, 1996</xref>). The studies addresses these challenges with focused facilitators, such as ICT investments and strategies, power backup measures, procurement policies prioritizing accessible devices (mobile-first), technical support personnel, LMS integration, and monitored lab environments for immersive experiences (
                    <xref ref-type="bibr" rid="ref6">Alhazza &amp; Yan, 2025</xref>; 
                    <xref ref-type="bibr" rid="ref66">Radianti et al., 2020</xref>).</p>
                <p>Instructional-design and pedagogical issues include poor incorporation of learning theory (e.g., Constructive Alignment), disjointed course design, and too much focus on novelty or usability rather than on objectively assessable learning outcomes, such as ambiguous congruence between TLA (teaching-learning activities), ILO (intended learning outcomes), and assessment (
                    <xref ref-type="bibr" rid="ref12">Balanyk, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref42">KO&#x00c7;, 2020</xref>; 
                    <xref ref-type="bibr" rid="ref7">Ali, 2018</xref>; 
                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>). Good practitioners stress use of pedagogical models such as TPACK, Constructive Alignment, and ADDIE, scaffolded iterative course development, genuine problem-solving activities, clear ILO-TLA-assessment coherence, and formative review loops (
                    <xref ref-type="bibr" rid="ref56">Mishra &amp; Koehler, 2006</xref>; 
                    <xref ref-type="bibr" rid="ref64">Pereira et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref24">Dilaines et al., 2024</xref>).</p>
                <p>The preparations of the staff are often limited by the lack of technological instructional skills, low levels of TPACK, resistance to change, fear of making mistakes, and busy schedule that limit their time to develop designs (
                    <xref ref-type="bibr" rid="ref25">Durdu &amp; Dag, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref60">Njuguna, 2020</xref>; 
                    <xref ref-type="bibr" rid="ref53">Mdodana-Zide, 2024</xref>; 
                    <xref ref-type="bibr" rid="ref15">Bergroth-Koskinen &amp; Sepp&#x00e4;l&#x00e4;, 2012</xref>). Facilitators include professional learning (e.g., sustained 12-week programs), reflective practice, micro-teaching, peer collaboration, mentoring, and mentoring models for faculty have been identified as facilitators for expanding instructional capacity and uptake (
                    <xref ref-type="bibr" rid="ref25">Durdu &amp; Dag, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref53">Mdodana-Zide, 2024</xref>).</p>
                <p>Challenges related to student preparedness, including digital literacy disparities, variable background knowledge, cognitive overload from inadequately scaffolded multimodal content, novelty effects, and hardware differences impacting user experience, impede learning improvements (
                    <xref ref-type="bibr" rid="ref20">Christodoulou &amp; Angeli, 2022</xref>; 
                    <xref ref-type="bibr" rid="ref77">Tamim et al., 2011</xref>; 
                    <xref ref-type="bibr" rid="ref37">Ibrahim et al., 2018</xref>; 
                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>). Facilitating strategies include orientation and onboarding processes, modular and sequenced content to reduce cognitive load, adaptive and personalized learning pathways, scaffolding with stepwise feedback, and mobile-friendly design (
                    <xref ref-type="bibr" rid="ref20">Christodoulou &amp; Angeli, 2022</xref>; 
                    <xref ref-type="bibr" rid="ref68">Ruge et al., 2019</xref>).</p>
                <p>Constraints such as delay, computational constraints, the limited haptic realism, usability constraints, the low reliability in prototypes, and the limited multimodal sensing fidelity of technology and system design limit the degree of fidelity and flexibility of educational environments (
                    <xref ref-type="bibr" rid="ref17">Biggs, 1996</xref>; 
                    <xref ref-type="bibr" rid="ref79">Treleaven &amp; Voola, 2008</xref>; 
                    <xref ref-type="bibr" rid="ref81">Wang et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref33">Han et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref85">Zhang et al., 2022</xref>). To better overcome these shortcomings, user-centered and participatory design, multimodal interaction, sensing enhancements, real-time feedback, iterative usability testing, and longitudinal follow-up are suggested (
                    <xref ref-type="bibr" rid="ref81">Wang et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref33">Han et al., 2025</xref>).</p>
                <p>Evaluations and generation of evidence are often short-term and varied, heavily relying on self-reporting focused on Level 1 to 2 outcomes rather than behavioral or longitudinal measures (Level 3 to 4) outcomes. Researchers have advocated for mixed-method, experimental, and longitudinal approaches, the linking of LA with performance data, larger sample sizes, and standardized metrics to enhance evidence (
                    <xref ref-type="bibr" rid="ref43">Lee et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref5">Alfredo et al., 2024</xref>; 
                    <xref ref-type="bibr" rid="ref28">Ford et al., 2017</xref>).</p>
                <p>Issues of ethics, privacy, and trust, e.g., data privacy and consent, algorithmic bias, the opacity of GenAI and learning-analytics systems, and the potential for an over-reliance on outputs of AI, and the risk of over-reliance on outputs of AI, call for governance mechanisms. Enablers to be up the ladder recommended are human-centered design, ethical governance framework, explainability mechanism, stakeholders involvement with instructors oversight and explicit data policies (
                    <xref ref-type="bibr" rid="ref70">Sajja et al., 2025</xref>; 
                    <xref ref-type="bibr" rid="ref4">Alfauzan &amp; Tarchouna, 2017</xref>; 
                    <xref ref-type="bibr" rid="ref52">Maor, 2016</xref>).</p>
                <p>Contextual and socio-economic factors, such as differences in device ownership and internet access, variations in technology usage at a regional level, along with limited adoption in the classroom, require mobile-accessible, low bandwidth options, adaptable delivery methods (blended/hybrid), contextualization to local learners, community collaboration, and supplementary financing (
                    <xref ref-type="bibr" rid="ref72">Sarrab et al., 2016</xref>; 
                    <xref ref-type="bibr" rid="ref50">Lutfi et al., 2022</xref>; 
                    <xref ref-type="bibr" rid="ref8">Ali &amp; Maliki, 2024</xref>). The literature as a whole showed that effective course development with emerging technologies requires substantive institutionally aligned support, pedagogically informed design, faculty development, learner-centered scaffolding, sound technical design, rigorous evaluation, ethical oversight, and sensitivity to context.</p>
            </sec>
        </sec>
        <sec id="sec23" sec-type="discussion">
            <title>Discussion</title>
            <sec id="sec24">
                <title>Conceptual synthesis of relationship between key variables</title>
                <p>The notion of the socio-technical system (STS) is fundamental to how emerging technologies can and do find their way into higher education curricula. A socio-technical system is a unity of social (people, organizations, culture) and technical (mechanical, hardware, software) components (
                    <xref ref-type="bibr" rid="ref13">Baxter &amp; Sommerville, 2011</xref>). In the Process of ETICD (Emerging Technologies Integration for Course Development) in Higher Education, STS serves as an analytical lens for understanding how technological changes (e.g., AI, LA, virtual environments) are institutionalized within the educational ecosystems. In order to show the strong relationships between different facets related to success in enabling technologies for development of courses, the integrated outcome is represented at each level of multi-level model (see 
                    <xref ref-type="fig" rid="f2">
Figure 2</xref>) as follows:</p>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>
Figure 2. </label>
                    <caption>
                        <title>Technology-Integrated Learning and Course Development: Conceptual Model.</title>
                    </caption>
                    <graphic id="gr2" orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/202024/178b4694-d058-4dbe-8e64-760010542462_figure2.gif"/>
                </fig>
            </sec>
            <sec id="sec25">
                <title>Interactions among design frameworks, technology types, and learning outcomes as rooted in socio-technical system: conceptual synthesis</title>
                <p>The quantitative synthesis provides evidence for a dynamic interrelation between the level of the instructional design framework and the technology type, which affects the learning outcome in TEL environments. Positive effects on learning outcomes were shown for all major design frameworks with effect size estimates calculated from the review ranging from moderate to very large. TPACK, CA, ADDIE, and DBR all systematically yielded moderate-to-large gains in learning, indicating that the presence of a structured pedagogical design process continues to be a key determiner of instructional effectiveness regardless of the technological modality. The Deep Learning framework was in particular outstanding with the largest pooled effect size, showing that the most recent technologies, which include AI, combined with mixed-reality systems can greatly improve learning performance if these are arranged in meaningful instructional sequences. These results underlie the assumption that the effectiveness of technology is mediated through the pedagogical design of the instruction, and not by the level of technological complexity.</p>
                <p>
                    <xref ref-type="fig" rid="f2">
Figure 2</xref> explains why these findings are so sensible: technological affordances, pedagogical design processes, conditions of institutional readiness, and learner outcomes are all systemically interconnected. In this model, the Technological Affordances Layer is the context of the functional features embedded in the digital tool (e.g., immersion, personalization, automation, interactivity). The quantitative findings indicate that high-experience; high-adaptive feedback techno-stimulators (e.g., augmented reality, virtual reality, artificial intelligence, adaptive learning systems) are more effective than more conventional types of digital delivery platforms. For instance, immersive technologies exhibited the largest average effect size across technology types, which were attributed to the support for experiential learning, acquisition of procedural skills, and conceptual understanding. Such results are consistent with cognitive theory and models of experiential learning in which active participation and situated practice is a dynamic facilitator for improved knowledge retention and transfer.</p>
                <p>The Pedagogical Design Layer of the model provides a lens into yet another process through which technological affordances are transformed into learning opportunities. It is suggestive of a clear cause in CA (and related models) of which the causes of optimal learning outcomes are &#x201c;the explicit alignment between learning objectives, teaching and learning activities, and assessment methods&#x201d;. When technologies were embedded in well-defined pedagogical sequences that involved scaffolding, formative feedback, and iterative refinement, studies are unanimous in reporting much more pronounced effects. In contrast, interventions that stressed technological novelty rather than systematic instructional design had relatively weaker or inconsistent effects on learning gains. This pattern bolsters the theoretical proposition that instructional design serves as the mediating through which technological potential is translated into educational effectiveness.</p>
                <p>Regarding organizational and institutional readiness, before the commencement of investigation on digital instructional practice, infrastructure, and human resources, institutional readiness was found to be a critical enabling factor affecting the implementation of technology-enhanced instruction. The review revealed the persistence of institutional barriers such as limited infrastructure, inadequate technical support, and a lack of sufficient professional development, which limited technology integration and teaching effectiveness. In contrast, an institution led by a culture that provided resources including digital infrastructure for students and faculty, as well as faculty training and technical support manifested more robust and sustainable learning outcomes. This is in line with Institutional Readiness Layer in the conceptual model, inferring that the organizational capacity and leadership is instrumental to the systemic adoption of educational technologies. The relationship between institutional resources and pedagogical design processes is a further indication of the need for attention to integrated, holistic approaches to institutional implementation rather than discrete technological initiatives.</p>
                <p>The Learner Outcomes Layer of the conceptual model describes the complexity of learning outcomes and includes dimensions of learning related to cognitive, affective, and behavioral aspects. The quantitative results showed that cognitive outcomes (e.g., knowledge gain and skills) were the most frequently evaluated and had the strongest impact among the studies. Positive changes in affective outcomes, including motivation, satisfaction and engagement, were also reported consistently across technology categories, with the most prominent effects evidenced in immersive and game-based learning environments. However, behavioral results and long-term transfer were less often evaluated and exhibited more inconsistent or weaker results. This discrepancy indicates that existing evaluation methods are more focused on short-term performance rather than on longer-term behavioral change, which is a major gap in the evidence base. The model&#x2003;predictions and loop nature explains this limitation and suggests that on-going assessment in iterative design phases is needed to capture short-term engagement as an indicator of long-term learning outcomes.</p>
                <p>The conceptual model is better illustrated by the complex interactions portrayed when considering the Technology Type x Instructional Duration. Results from the review show that the majority of longer duration interventions (i.e., more than two weeks) appeared to have larger effects on learning than short-duration interventions. Long exposure time enables students to get used to new technological instruments, increases their procedural fluency, and involves them in continuous practice, which enhances knowledge storage and knowledge transfer. The result supports the model&#x2019;s focus on temporal dynamics and iterative refinement processes in pedagogical design cycle. Similarly, learner participants&#x2019; prior knowledge and level of digital literacy also moderated learning results, which coincides with cognitive load theory and the expertise-reversal effect. These moderating variables indicate that the effectiveness of a technique changes based not only on its inherent quality, but how well that pedagogical complexity matches the maturity of the learners.</p>
                <p>The synthesis also illustrates the presence of engagement as a mediating variable linking the technological affordances and learning outcomes. Regardless of technology type, indicators of engagement (including attention, participation, persistence and motivation) all significantly improved after technology adoption. Immersive and game-based contexts had even more pronounced engagement effects, a result of their interactive and experiential nature.</p>
                <p>From a theoretical standpoint, the integrated results provide robust support for the STS model that underpinned the conceptual model. Socio-technical theory states that the performance of an organization results from the joint optimization of its technological, human and organizational subsystems. The result of this review is that success in technology-enhanced learning environments seems to be contingent upon a systemic coordination of these factors. Technology innovation by itself does not guarantee enhanced learning results, but the effectuality of innovation is exhibited when technology is incorporated within pedagogically sound instructional designs supported by institutional infrastructure and aligned with learner needs. The multi-level nature of the conceptual model can hence be seen as an adequate representation of the &#x2018;nested&#x2019; processes that influence student achievements in digitally mediated learning environments.</p>
                <p>Taken together, these results indicate that technology-enhanced learning is best viewed as a systemic type of process, and not simply as a singular teaching intervention. The most profound learning gains occurred when technological tools were incorporated within well-organized instructional sequences, in a climate of institutional readiness, and when subject to ongoing evaluation through feedback loops. This systems-level analysis reframes the target of educational reform from technology adoption to instructional design quality and organizational capacity. In sum, prospective research needs to emphasize longitudinal designs, standardized outcome measurements, and assessment of implementation fidelity to bolster the empirical base for technology-enhanced course development.</p>
            </sec>
        </sec>
        <sec id="sec26" sec-type="conclusion">
            <title>Conclusion</title>
            <p>The evidence from this systematic review indicates that new and emerging technologies have the potential to effectively support course development if the implementation is informed by a coherent pedagogy design, and supported by the institutional and contextual factors. Instructional design models such as TPACK, CA, ADDIE, and DBR, were among those reviewed, and cumulatively, across the studies, these models resulted in moderate to large positive effects on student learning (mean standardized effect estimate ranging from d&#x00a0;=&#x00a0;0.65 to d&#x00a0;=&#x00a0;0.74). To the best of the authors&#x2019; knowledge, the largest effect has been identified in deep learning-based framework combined with artificial intelligence and mixed reality technologies (d&#x00a0;=&#x00a0;1.30), demonstrating the significant potential of advanced intelligent/immersive technology in improving learning when integrated with pedagogical application. On the other hand, hybrid or loosely coupled models appeared to bring more modest effects, adding weight to the conclusion that the use of technology by itself does not lead to better educational results. Instead, the alignment of learning goals, instructional activities, and assessment methods continues to be a key factor in determining the effectiveness of instruction.</p>
            <p>This review also reinforces that quality teaching is moderated by different kinds of technology in terms of effect on outcomes for engagement and learning. Immersive technologies (augmented reality, virtual reality, and mixed reality) had the greatest overall effect on learning outcomes with large mean effect sizes and high levels of engagement indicators. Likewise, AI, generative AI, and ALS (adaptive learning systems) achieved statistically significant gains in cognitive performance, learner motivation, and SLR (self-regulated learning) behaviors. Game-based learning technology and mobile learning technology also demonstrated positive effects on students&#x2019; engagement and learning achievement, however, their effects were more or less varied by instructional alignment or design quality. Gains in engagement were often reported, especially in affective and cognitive domains, albeit the information on sustained behavioral change and longer-term learning transfer was still scarce. This is characteristic of technology-enhanced learning environments, which appear to consistently yield positive short-term learning and motivation outcomes, but often need longer-term investigation to assess enduring educational outcomes.</p>
            <p>Addressing the third research question, the synthesis revealed a small number of contextual, institutional, and pedagogical factors that have been repeatedly cited as either facilitators or barriers to successful technology integration in course development. Institutional readiness, faculty professional development, infrastructure reliability, learner digital literacy, and ethical governance mechanisms were identified as key enablers. In contrast, prevalent barriers were poor connectivity, inadequate instructional design expertise, brief intervention lengths, and unequal access to digital materials. The conceptualization conceived in this review demonstrates how TEC development sits within a socio-technical system, where technological affordances, pedagogical design, institutional preparedness and learner attributes are all interacting and contributing to learning outcomes and achievement. Thus, effective practice involves more than technology, and having the other system components that align and function in holistic manner is necessary for effective adoption of technology in education.</p>
        </sec>
        <sec id="sec27">
            <title>Implications</title>
            <p>The results of this review will have significant consequences for practice, policy, and research related to TEC development. Educators and course designers, first and foremost, should emphasize pedagogical integration as opposed to technological innovation. The consistent moderate-to-large effect sizes observed for models such as TPACK, CA, or ADDIE indicate that structured instructional design is needed to transform technological affordances into observable learning gains. Hence, institutions should treat evidence-based design models as a best practice in course design and support full transparency among learning outcomes, teaching-learning activities, and assessment measures. Such alignment fosters not only instructional coherence, but also reliability and replicability of learning outcomes across different educational settings.</p>
            <p>Second, institutions need to make strategic investments in its faculty professional development and teaching support services that assist in building their faculty&#x2019;s digital teaching competencies. The review found that the most significant enabler for the integration of technology was the faculty&#x2019;s readiness, and this was positively influenced by ongoing professional development programs, mentorship models, and collegial design practices. In particular, training interventions should be aimed in increasing educators&#x2019; ability to scaffold learning, offer adaptive feedback, and regulate cognitive load in technology enriched learning environments. More may be gained by building institutional capacity in these areas than by investing unquestioningly in additional hardware or software.</p>
            <p>Third, the results demonstrate the necessity for system-level and long-term planning to facilitate the sustainable adoption of nascent technologies. Infrastructure dependability, fair access to devices, to connectivity, and to technical support services were cited as fundamental prerequisites for effective technology-enhanced learning. Investments in resilient digital infrastructure, in learning solutions that can be delivered in low bandwidth and through mobile devices, and in inclusive technology policies that address socioeconomic barriers to access should be the top priorities for policymakers and institutional leaders. Such investments tend to be critical in under-resourced educational settings where infrastructure constraints can severely attenuate the impact of technology-based interventions.</p>
            <p>Fourth, researchers should broaden the evaluative lens to include behavioral, longitudinal, and organizational-level proxies of learning effectiveness rather than a focus on temporally-limited cognitive outcomes. The review identified chronic underreporting in the measurement of sustained behavior change, transfer of knowledge and long-term academic achievement. We encourage researchers to utilize mixed-method and longitudinal research designs, standardized measurement frameworks, and LA platforms and systems of systems to produce more robust and generalizable evidence concerning the long-term effects of TEL environments. In addition, future research should also investigate cost-effectiveness, potential for scale, and context-specific adaptability to inform evidence-based decision-making in educational policy and practice.</p>
            <p>In the end, ethical considerations around technology use and application should be woven into the technology-enhanced course at all levels. As AI and LA systems become increasingly common in education, the associated issues around data privacy, algorithmic bias, transparency, and learner autonomy are likely to escalate. Institutions ought to define clear data governance policies, ensure transparency in algorithmic decision-making, and uphold human agency in technology-mediated instruction. The ethical and equitable use of educational technologies is critical to build trust with stakeholders and to maintain the long-term innovation of learning systems.</p>
        </sec>
    </body>
    <back>
        <sec id="sec28" sec-type="data-availability">
            <title>Data availability statement</title>
            <p>All data supporting the findings of this study are openly available in the Zenodo repository under an open-access license (CC0): 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.5281/zenodo.19732174">

                    <sans-serif>https://doi.org/10.5281/zenodo.19732174</sans-serif>
</ext-link> (
                <xref ref-type="bibr" rid="ref29">Geleto et al., 2026</xref>).</p>
            <p>The following materials have been deposited:
                <list list-type="bullet">
                    <list-item>
                        <label>&#x2713;</label>
                        <p>Completed PRISMA checklist</p>
                    </list-item>
                    <list-item>
                        <label>&#x2713;</label>
                        <p>PRISMA flow diagram</p>
                    </list-item>
                    <list-item>
                        <label>&#x2713;</label>
                        <p>Study screening and selection dataset</p>
                    </list-item>
                    <list-item>
                        <label>&#x2713;</label>
                        <p>Extracted data used for analysis</p>
                    </list-item>
                    <list-item>
                        <label>&#x2713;</label>
                        <p>Variables and coding framework</p>
                    </list-item>
                    <list-item>
                        <label>&#x2713;</label>
                        <p>Values underlying figures and tables</p>
                    </list-item>
                </list>
            </p>
        </sec>
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        <front-stub>
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                <article-title>Reviewer response for version 2</article-title>
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                    <name>
                        <surname>Sison</surname>
                        <given-names>Louis Robert C.</given-names>
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                    <label>1</label>Bulacan State University, Bulacan, Philippines</aff>
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            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>2</day>
                <month>6</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Sison LRC</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport485050" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.179684.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>1. The introduction clearly establishes the need to examine emerging technologies in higher education course development, and the research questions are explicitly stated. The paper also situates the review within pedagogical frameworks such as TPACK, ADDIE, Constructive Alignment, and DBR.&#x00a0;</p>
            <p> 2. The paper provides databases, search strings, eligibility criteria, PRISMA screening, data extraction procedures, and MMAT appraisal. However, replication would be stronger if the authors further clarified reviewer screening procedures, discrepancy resolution, and the validation process for NotebookLM-assisted extraction.</p>
            <p> 3. The descriptive quantitative synthesis is useful, but is should not be interpreted as a formal meta-analysis. The paper averages effect sizes without weighting by sample size or variance and does not report heterogeneity, confidence intervals, or publication bias. Therefore, the findings should be framed as indicative trends rather than definitive effect estimates.</p>
            <p> 4. The conclusions are generally supported because the results consistently show that emerging technologies are most beneficial when aligned with sound pedagogy, institutional readiness, and learner needs. However, conclusions about "strongest effects" should be softened because the quantitative results are descriptive rather than meta-analytic.&#x00a0;</p>
            <p> </p>
            <p> Generally, the paper is scientifically acceptable and contributes meaningfully to technology-enhanced higher education research, but it still has important reservations, especially regarding the framing and interpretation of the quantitative synthesis.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Not applicable</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Teacher Education, Educational Technology, Mathematics Education</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report485046">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.202024.r485046</article-id>
            <title-group>
                <article-title>Reviewer response for version 2</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Dumagay</surname>
                        <given-names>Alexandhrea Hiedie</given-names>
                    </name>
                    <xref ref-type="aff" rid="r485046a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0009-0004-5370-1756</uri>
                </contrib>
                <aff id="r485046a1">
                    <label>1</label>Western Mindanao State University, Zamboanga City, Philippines</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>2</day>
                <month>6</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Dumagay AH</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport485046" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.179684.2"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This manuscript addresses a timely and relevant issue in higher education by reviewing the integration of emerging technologies in course development and pedagogical practice. The topic is important given the growing use of artificial intelligence, immersive technologies, learning analytics, and digital instructional tools across higher education institutions. The manuscript also provides a broad overview of instructional design frameworks, including TPACK, Constructive Alignment, ADDIE, and Design-Based Research, and attempts to relate these frameworks to learning outcomes and pedagogical effectiveness.</p>
            <p> One of the strengths of the paper lies in its wide literature coverage and its effort to synthesize findings from multiple technology domains within a single review. The discussion of design frameworks and their relationship to learning outcomes is particularly useful, as is the attempt to interpret the findings through a socio-technical systems perspective. The inclusion of institutional, pedagogical, and learner-related factors further strengthens the discussion by acknowledging that technology integration depends on more than technological availability alone.</p>
            <p> At the same time, some aspects of the review would benefit from further clarification. Although the manuscript states that PRISMA procedures were followed, the methodological reporting could be strengthened. In particular, the procedures used for assessing study quality and risk of bias are not clearly described. Since the review includes 76 studies with diverse methodologies and contexts, additional explanation regarding how study quality and heterogeneity were addressed would improve confidence in the synthesis.</p>
            <p> The organization of the manuscript could also be improved in some sections. Discussions of technology benefits, engagement outcomes, and implementation challenges occasionally overlap and repeat similar ideas. Greater condensation and clearer transitions may help improve readability and maintain the flow of argument. In addition, the early discussion of the Ethiopian policy and higher education context is informative, although its connection to the later synthesis and conclusions could be made more explicit.</p>
            <p> The paper appropriately highlights the importance of pedagogical alignment, institutional readiness, and faculty competence in successful technology integration. However, the manuscript itself notes the limited availability of longitudinal and behavioral evidence, and this limitation may deserve stronger emphasis in the discussion and conclusion. While many studies report positive engagement and cognitive outcomes, longer-term impacts and transfer effects appear less consistently documented.</p>
            <p> Overall, this manuscript addresses an important topic and offers a potentially valuable synthesis of research on emerging technologies and higher education course development. The paper could make a useful contribution to discussions of technology-enhanced learning and instructional design.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Not applicable</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Education, AI in Education, Educational Technology</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report485048">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.198223.r485048</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Triantafyllou</surname>
                        <given-names>Serafeim A.</given-names>
                    </name>
                    <xref ref-type="aff" rid="r485048a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-2115-8934</uri>
                </contrib>
                <aff id="r485048a1">
                    <label>1</label>Aristotle University of Thessaloniki, Thessaloniki, Greece</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>18</day>
                <month>5</month>
                <year>2026</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Triantafyllou SA</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport485048" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.179684.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve-with-reservations</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The manuscript addresses an important and timely topic concerning the integration of emerging technologies into higher education course development. The review is broad in scope and provides useful synthesis regarding instructional design frameworks, learning outcomes, and institutional factors influencing implementation. The inclusion of frameworks such as TPACK, Constructive Alignment, ADDIE, and DBR adds conceptual coherence to the discussion.</p>
            <p> The introduction is comprehensive and clearly motivates the review. The research questions are explicit and relevant. The PRISMA-based structure strengthens transparency, and the manuscript includes substantial descriptive synthesis of technology types, pedagogical models, and implementation challenges.</p>
            <p> However, there are methodological concerns that limit the rigor of the quantitative synthesis. Although the manuscript reports &#x201c;pooled&#x201d; effect sizes, the statistical aggregation procedures do not constitute a formal meta-analysis. Effect sizes appear to be averaged without weighting by sample size or variance, and there is no assessment of heterogeneity, confidence intervals, publication bias, or study quality/risk of bias. These omissions weaken the strength of the statistical conclusions. The authors should either frame the quantitative synthesis more cautiously as descriptive aggregation or conduct a more rigorous meta-analytic procedure.</p>
            <p> The methods section would also benefit from greater detail to improve reproducibility. Specifically, the manuscript should provide complete database search strings, screening procedures between reviewers, inter-rater agreement measures, and explicit criteria for study quality appraisal. The use of NotebookLM during extraction should also be clarified further, including how accuracy and reliability were ensured.</p>
            <p> Some sections contain language and formatting inconsistencies, typographical issues, and citation irregularities that require careful proofreading. Tables are informative, but some effect-size calculations and terminology should be clarified for consistency.</p>
            <p> Despite these concerns, the manuscript contributes meaningfully to the literature on technology-enhanced learning and provides useful conceptual synthesis for researchers and practitioners.</p>
            <p>Are the rationale for, and objectives of, the Systematic Review clearly stated?</p>
            <p>Yes</p>
            <p>Is the statistical analysis and its interpretation appropriate?</p>
            <p>Partly</p>
            <p>If this is a Living Systematic Review, is the &#x2018;living&#x2019; method appropriate and is the search schedule clearly defined and justified? (&#x2018;Living Systematic Review&#x2019; or a variation of this term should be included in the title.)</p>
            <p>Not applicable</p>
            <p>Are sufficient details of the methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results presented in the review?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Educational Technology, Gamification, Computational Thinking, Intelligent Tutoring Systems, Artificial Intelligence in Education, Didactics</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.</p>
        </body>
    </sub-article>
</article>
