<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="systematic-review" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.183150.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Systematic Review</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>A scoping review on the use of Research Development Awards by research funding organisations in the UK and beyond.</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: awaiting peer review]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Blatch-Jones</surname>
                        <given-names>Amanda</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-1486-5561</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Giddins</surname>
                        <given-names>Beth</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Church</surname>
                        <given-names>Hazel</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>National Institute for Health and Care Research (NIHR) Coordinating Centre, University of Southampton School of Healthcare Enterprise and Innovation, Southampton, Hampshire, SO167NS, UK</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:ajy5@soton.ac.uk">ajy5@soton.ac.uk</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>9</day>
                <month>6</month>
                <year>2026</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2026</year>
            </pub-date>
            <volume>15</volume>
            <elocation-id>897</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>28</day>
                    <month>5</month>
                    <year>2026</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2026 Blatch-Jones A et al.</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/15-897/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Research Development Awards (RDAs), also referred to as seed funding or development grants, are widely used by research funding organisations to support early-stage research activity, collaboration, and capacity building. Despite their widespread use across disciplines and funding systems, evidence on their purpose and outcomes remains fragmented, limiting opportunities for cross-funder learning and evidence-informed funding decisions. This review synthesises the evidence on RDAs across disciplinary and geographical contexts, examining their intended purpose, benefits, challenges, and contribution within wider research funding ecosystems.</p>
                </sec>
                <sec>
                    <title>Methods</title>
                    <p>A scoping review methodology was undertaken due to the conceptual and methodological diversity of the literature. The search strategy was limited to the last ten years (2015-2025) and included UK and international academic and grey literature. Searches were conducted in Scopus and Web of Science on 9 May 2025, with supplementary searching using Google Scholar, Sci-Space, and citation tracking of key articles. Data were extracted and synthesised across five research questions addressing the purpose, context, benefits, challenges, and outcomes of RDAs.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>A total of 998 records were identified, of which 102 articles met the eligibility criteria and included for full extraction. The evidence described RDAs as flexible, early-stage mechanisms designed to enable collaboration, build research capacity, and support future funding opportunities. RDAs were particularly valued for fostering partnerships, supporting community-engaged and interdisciplinary research. However, recurrent challenges included short award duration, limited funding, misalignment with traditional evaluation metrics, and difficulties evidencing longer-term or relational outcomes. Sustained impact was frequently contingent on follow-on funding and supportive institutional contexts.</p>
                </sec>
                <sec>
                    <title>Conclusion</title>
                    <p>RDAs function most effectively as enabling components within wider funding ecosystems rather than as stand-alone interventions. Their value lies in supporting readiness, relationship-building, and pathway creation, often beyond the life of the award. This review provides a cross-disciplinary foundation to support more transparent, evidence-informed design and evaluation of RDAs.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>Research Development Awards; Research Funding Organisations; Seed Funding; Acceleration Awards; Networking Grants; Innovation Awards; Capacity Building; Scoping Review.</kwd>
            </kwd-group>
            <funding-group>
                <funding-statement>The author(s) declared that no grants were involved in supporting this work.</funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <def-list>
            <title>Abbreviations</title>
            <def-item>
                <term id="G15">AI</term>
                <def>
                    <p>Artificial Intelligence</p>
                </def>
            </def-item>
            <def-item>
                <term id="G17">CBPR</term>
                <def>
                    <p>Community-Based Participatory Research</p>
                </def>
            </def-item>
            <def-item>
                <term id="G22">COST</term>
                <def>
                    <p>
European Cooperation in Science and Technology</p>
                </def>
            </def-item>
            <def-item>
                <term id="G13">COVID</term>
                <def>
                    <p>Coronavirus Disease 2019</p>
                </def>
            </def-item>
            <def-item>
                <term id="G7">CTSA</term>
                <def>
                    <p>Clinical and Translational Science Awards</p>
                </def>
            </def-item>
            <def-item>
                <term id="G6">EAGER</term>
                <def>
                    <p>Early-concept Grants for Exploratory Research</p>
                </def>
            </def-item>
            <def-item>
                <term id="G16">ECRs</term>
                <def>
                    <p>Early Career Researchers</p>
                </def>
            </def-item>
            <def-item>
                <term id="G23">EDCTP</term>
                <def>
                    <p>
European and Developing Countries Clinical Trials Partnership</p>
                </def>
            </def-item>
            <def-item>
                <term id="G21">EIC</term>
                <def>
                    <p>
European Innovation Council</p>
                </def>
            </def-item>
            <def-item>
                <term id="G8">ESSENCE</term>
                <def>
                    <p>Essence Seven Principles for Strengthening Research Capacity in Low and Middle Income Countries</p>
                </def>
            </def-item>
            <def-item>
                <term id="G25">GLOHRA</term>
                <def>
                    <p>German Alliance for Global Health Research</p>
                </def>
            </def-item>
            <def-item>
                <term id="G26">GPT</term>
                <def>
                    <p>Generative Pre-trained Transformer</p>
                </def>
            </def-item>
            <def-item>
                <term id="G3">IAA</term>
                <def>
                    <p>UK Research and Innovation&#x2019;s Impact Acceleration Accounts</p>
                </def>
            </def-item>
            <def-item>
                <term id="G10">JBI</term>
                <def>
                    <p>Joanna Briggs Institute</p>
                </def>
            </def-item>
            <def-item>
                <term id="G19">LMIC-HIC
</term>
                <def>
                    <p>Low and Middle Income Countries &#x2013; High Income Countries</p>
                </def>
            </def-item>
            <def-item>
                <term id="G4">NIH</term>
                <def>
                    <p>US National Institutes for Health</p>
                </def>
            </def-item>
            <def-item>
                <term id="G9">NIHR</term>
                <def>
                    <p>National Institute for Health and Care Research</p>
                </def>
            </def-item>
            <def-item>
                <term id="G5">NSF</term>
                <def>
                    <p>US National Science Foundation</p>
                </def>
            </def-item>
            <def-item>
                <term id="G12">PHIRST</term>
                <def>
                    <p>Public Health Intervention Responsive Studies Teams</p>
                </def>
            </def-item>
            <def-item>
                <term id="G24">REACH</term>
                <def>
                    <p>Research Evidence into Action for Clean Water</p>
                </def>
            </def-item>
            <def-item>
                <term id="G14">PRISMA-ScR
</term>
                <def>
                    <p>Systematic Reviews and Meta-analyses extension for scoping review</p>
                </def>
            </def-item>
            <def-item>
                <term id="G1">RDA</term>
                <def>
                    <p>Research Development Awards</p>
                </def>
            </def-item>
            <def-item>
                <term id="G2">RFO</term>
                <def>
                    <p>Research Funding Organisations</p>
                </def>
            </def-item>
            <def-item>
                <term id="G11">RPO</term>
                <def>
                    <p>Research Performing Organisations</p>
                </def>
            </def-item>
            <def-item>
                <term id="G18">RQ</term>
                <def>
                    <p>Research Question</p>
                </def>
            </def-item>
            <def-item>
                <term id="G20">UKRI</term>
                <def>
                    <p>UK Research and Innovation</p>
                </def>
            </def-item>
        </def-list>
        <sec id="sec5" sec-type="intro">
            <title>Introduction</title>
            <p>Research Funding Organisations (RFOs) employ a diverse portfolio of programmes to fund research, ranging from large-scale project and programme grants to fellowships, infrastructure development, and targeted capacity-building initiatives. Within such initiatives, Research Development Awards (RDA), also referred to as seed funding, catalyst funding, acceleration funding or application development funding, represent one of several approaches used by RFOs to stimulate early-stage research ideas, foster collaboration, and enable preparatory work for future larger-scale funded research. These awards are typically short in duration and modest in cost, offering flexibility to explore innovative concepts, build partnerships, and strengthen research communities. UK Research and Innovation&#x2019;s Impact Acceleration Accounts (IAAs), Wellcome&#x2019;s Seed Awards, the US National Institutes of Health (NIH) R21 exploratory grants, the US National Science Foundation&#x2019;s (NSF) Early-concept Grants for Exploratory Research (EAGER) grants, and the global seed programmes such as Grand Challenges Canada&#x2019;s Stars in Global Health
                <sup>
                    <xref ref-type="bibr" rid="ref1">1</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref6">6</xref>
                </sup> demonstrate the wide use of RDAs across disciplines and contexts. Together, these schemes highlight the strategic role of RDAs in addressing gaps in research development and capacity building, particularly in emerging areas such as interdisciplinary research and novel methodologies. By providing flexible, low-risk funding, RDAs complement larger-scale investments and contribute to a more diverse, sustainable, and responsive research landscape.</p>
            <p>
Despite, the increasing use of RDAs, the evidence remains limited and fragmented. Formal evaluations are sparse, and what evidence there is often relies on proxy indicators (e.g., follow-on funding or publications) or are focused on career development awards that do not capture the broader benefits of RDAs such as partnership quality, capacity development, equity, and translational impact.
                <sup>
                    <xref ref-type="bibr" rid="ref7">7</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref9">9</xref>
                </sup> A recent cross-hub analysis of Clinical and Translational Science Awards (CTSA) pilot projects reported low publication rates and data quality limitations, while an international review of RFO&#x2019;s knowledge translation approaches found diverse mechanisms with limited empirical evidence underpinning research funding practices.
                <sup>
                    <xref ref-type="bibr" rid="ref10">10</xref>
                </sup> These findings highlight the persistent gaps in understanding the effectiveness, optimal design, and contextual applicability of RDAs. Further challenges include inconsistent definitions and practices as RDAs vary in size, duration, and purpose across research programmes, making comparisons and best-practice development difficult. In addition, there is limited evidence on when RDAs are most effective, the challenges they present, and how they contribute to the wider research ecosystem.</p>
            <p>
These gaps are a concern given that the purpose and focus of RDAs are to strengthen research ecosystems, build capacity, and enhance impact pathways. With the lack of synthesised evidence, RDAs risk being assessed against narrow or inappropriate success metrics, such as short-term outputs or follow-on funding alone, which do not reflect their developmental and relational aims. This limits funders&#x2019; ability to design proportionate awards, align expectations with intended outcomes, and learn systematically from past funding investments. More broadly, weak or fragmented evidence constrains understanding of when and how RDAs add value within the funding landscape, potentially leading to inconsistent use, sub-optimal design choices, and under-recognition of their contribution to longer-term research capability and impact. For example, although the ESSENCE Good Practice series offers global guidance for RFOs,
                <sup>
                    <xref ref-type="bibr" rid="ref11">11</xref>,
                    <xref ref-type="bibr" rid="ref12">12</xref>
                </sup> placing emphasis on evidence-informed capacity strengthening, robust monitoring and evaluation, and equitable partnership models, systematic synthesis of how RDAs function across disciplines and locations remain limited. This lack of evidence is particularly problematic in light of growing policy interest in deploying RDAs more strategically and extensively. Without a robust evidence base, decisions about when and how to use these awards risk being inconsistent or suboptimal, potentially limiting their value and impact.</p>
            <p>To address these needs, we conducted a scoping review of RDAs used by RFOs in the UK and beyond. This review forms part of a broader work programme that also included stakeholder consultation with research management staff at a UK national health research funder (National Institute for Health and Care Research, NIHR) spanning strategic commissioning, application and funding, and monitoring and reporting, across both domestic and global research programmes.</p>
            <p>To support RFOs and policymakers in designing effective, proportionate funding mechanisms that foster collaboration and capacity building, a scoping review was conducted to answer the following questions:
                <list list-type="order">
                    <list-item>
                        <label>1.</label>
                        <p>How does the evidence describe the purpose of RDAs (also known as seed funding, prime and catalyst funding)?</p>
                    </list-item>
                    <list-item>
                        <label>2.</label>
                        <p>How does the evidence describe the intended outcomes, benefits, and challenges of RDAs?</p>
                    </list-item>
                    <list-item>
                        <label>3.</label>
                        <p>Does the evidence suggest RDAs are best suited in a particular context?</p>
                    </list-item>
                    <list-item>
                        <label>4.</label>
                        <p>Does the evidence suggest any specific outcomes (e.g. building relationships) that RDAs are particularly well-suited to achieving?</p>
                    </list-item>
                    <list-item>
                        <label>5.</label>
                        <p>To what extent does the evidence suggest that RDAs achieve the outcomes they set out to?</p>
                    </list-item>
                </list>
            </p>
            <p>By synthesising the available evidence, the review also serves a broader purpose by contributing to the global research funding landscape, offering insights that can inform optimal research practices across disciplines and international contexts. Given the scarcity of existing evaluations, this review represents an opportunity for RFOs to lead in generating transparent, evidence-informed guidance on the role and value of RDAs.</p>
        </sec>
        <sec id="sec6" sec-type="methods">
            <title>Methods</title>
            <p>Due to the complexity, uncertainty and nature of the available research (in terms of source, type, and audience), a scoping review methodology was undertaken. Scoping reviews are relevant to addressing research questions on priorities for research, clarification on concepts and definitions and providing research frameworks or background information. Scoping reviews typically identify evidence gaps or scope the body of literature rather than seeking to describe experiences or current practice.
                <sup>
                    <xref ref-type="bibr" rid="ref13">13</xref>
                </sup> Scoping reviews ask the question, &#x2018;What has been done previously?&#x2019;, &#x2018;What does the literature say?&#x2019; compared to systematic reviews that ask the question &#x2018;Does this intervention work for this group of patients?&#x2019; Scoping review methodology does not judge the quality of the evidence but rather maps the evidence. The JBI scoping review framework was used to guide the development of the review (
                <ext-link ext-link-type="uri" xlink:href="https://jbi.global/scoping-review-network">https://jbi.global/scoping-review-network</ext-link>).
                <sup>
                    <xref ref-type="bibr" rid="ref14">14</xref>
                </sup> A framework was developed to cover the five research questions:
                <list list-type="order">
                    <list-item>
                        <label>1.</label>
                        <p>

                            <bold>The purpose and context of Research Development Awards</bold> (
                            <bold>RQ1</bold>: How does the evidence describe the purpose of RDAs? 
                            <bold>RQ3</bold>: Does the evidence suggest RDAs are best suited in a particular context?) (e.g., the duration, cost variation, type of award, purpose and focus of the award).</p>
                    </list-item>
                    <list-item>
                        <label>2.</label>
                        <p>

                            <bold>How does the evidence describe the intended outcomes, benefits, and challenges of Research Development Awards?</bold> (
                            <bold>RQ2)</bold> (e.g., what are the intended outcomes, why is the research needed, the benefits, potential value/solutions, the challenges, barriers to implementation, research and policy recommendations and considerations).</p>
                    </list-item>
                    <list-item>
                        <label>3.</label>
                        <p>

                            <bold>Do Research Development Awards achieve their intended outcomes?</bold> (
                            <bold>RQ4</bold>: Does the evidence suggest any specific outcomes that RDAs are particularly well-suited to achieving? 
                            <bold>RQ5</bold>: To what extent does the evidence suggest that RDAs achieve the outcomes they set out to?) (e.g., did it achieve what it set out to do, and applicability for research funders, policy and decision-makers, researchers, and other stakeholders).</p>
                    </list-item>
                </list>
            </p>
            <p>For consistency, all findings were reported using this framework. This approach ensures alignment across the research questions, facilitates comparison of evidence, and provides a structured basis for interpreting implications for RFOs, policy and decision-makers, researchers, and other stakeholders.</p>
            <sec id="sec7">
                <title>Eligibility criteria</title>
                <p>As highlighted in the literature, RDAs are described using a wide range of terms and are designed to serve multiple purposes and outcomes. These range from awards primarily focused on individual career or skills development, to those intended to support community-engaged, collaborative, or capacity-building activity at team or institutional level. This variation in terminology and intent reflects differences in funding systems and contexts, but also creates challenges for evidence synthesis, as awards labelled similarly may differ substantially in purpose, scope, and expected outcomes. Prior to conducting the review (e.g., defining the key terms and conducting the academic searches) it was essential to establish a clear definition of what constituted an RDA. This clarity provided the foundation for developing the eligibility criteria for the review.
                    <list list-type="bullet">
                        <list-item>
                            <label>&#x2022;</label>
                            <p>

                                <bold>Purpose of a RDA</bold>: Laying the groundwork for larger grants; proof-of-concept studies and proposal development; establishing collaboration and partnerships; building research capacity; supporting knowledge translation and community engagement.</p>
                        </list-item>
                        <list-item>
                            <label>&#x2022;</label>
                            <p>

                                <bold>Common features of a RDA</bold>: Short duration, modest budgets and flexible spending rules; intended outcomes focused on enabling future funding, strengthening networks, and generating preliminary outputs; support interdisciplinary teams.</p>
                        </list-item>
                    </list>
                </p>
                <p>

                    <bold>

                        <italic toggle="yes">Context</italic>
</bold>
                </p>
                <p>The context included UK, European, and international settings across all sectors, fields, and disciplines.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Participants</italic>
</bold>
                </p>
                <p>Any Research Funding Organisation (RFO) or institutional sector from any discipline or field of research. This also included Research Performing Organisations (RPOs), private sector businesses and enterprises, and public administrations that fund RDAs (e.g., funder perspective) or those that received a RDA (e.g., funded/researcher perspective).</p>
                <p>

                    <bold>

                        <italic toggle="yes">Inclusion criteria</italic>
</bold>
                </p>
                <p>Articles were included if they were written in the English language (or could be translated into English), available in full text, and focused on team, partnership or collaborative awards rather than career, personal, or individual development awards such as fellowships. 
                    <xref ref-type="table" rid="T1">
Table 1</xref> outlines the original inclusion criteria used in the evidence synthesis in more detail (refer to extended data 
                    <bold>S1 Table: Descriptors for field and setting</bold>).</p>
                <table-wrap id="T1" orientation="portrait" position="float">
                    <label>
Table 1. </label>
                    <caption>
                        <title>Original inclusion criteria.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Inclusion criteria</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Description</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Meets the definition for Research Development Award</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">An award that is relatively short in duration and low in cost, focuses on building collaboration, research capacity and partnerships, supports translation of knowledge and builds the foundations for future larger and longer funded awards. 
                                    <italic toggle="yes">Sometimes called Pump Prime and Catalyst.</italic>

                                    <break/>

                                    <bold>Awards focusing on career development are excluded from this definition</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Meets at least one of the following criteria</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <p>

                                        <list list-type="bullet">
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Building collaboration/networking</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research capacity and partnerships</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Supporting translation of knowledge</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Stimulate the research community and build research readiness</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Lay the foundations of future and longer NIHR-supported awards</p>
                                            </list-item>
                                        </list>
                                    </p>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Funding Award duration</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to 18 months</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Funding Award amount</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to &#x00a3;200,000</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Known descriptors for Research Development Awards</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Seed Funding
                                    <break/>Catalyst Awards
                                    <break/>Pump Prime Funding
                                    <break/>Research Collaboration Funding
                                    <break/>Development Awards (Specifically labelled as such)
                                    <break/>Programme Development Grants
                                    <break/>Acceleration Awards
                                    <break/>Research Capacity Awards</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>

                    <bold>

                        <italic toggle="yes">Exclusion criteria</italic>
</bold>
                </p>
                <p>Personal development awards, including any integrated clinical academic programmes, fellowship awards, career development awards, Public Health Intervention Responsive Studies Teams (PHIRST) awards, entrepreneurships, incubator awards associated to venture capital, funds or investment, and start-ups, including incubation centres.</p>
            </sec>
            <sec id="sec8">
                <title>Types of sources</title>
                <p>The scoping review considered all types of study designs for inclusion (e.g., randomised controlled trials, non-randomised controlled trials, before and after studies and interrupted time-series studies, analytical observational studies including prospective and retrospective cohort studies, case-control studies, analytical cross-sectional studies, descriptive observational study designs including case series, individual case reports and descriptive cross-sectional studies).</p>
                <p>Qualitative studies that focused on qualitative data including, but not limited to, designs such as phenomenology, grounded theory, ethnography, qualitative description, action research and feminist research were also considered. In addition, systematic reviews, text and opinion papers that met the inclusion criteria were eligible for inclusion.</p>
                <p>A broad range of publication data were required to be as inclusive as possible due to the diverse nature of how RDAs are reported and discussed in the public domain (and its associated parts in open research and open access). On that basis, the review included traditional academic outputs such as peer-reviewed journal articles, commentaries, editorials, opinion letters, perspectives and preprints, and grey literature such as policy documents, blogs, educational articles, guidance and newsletters, and reports.</p>
            </sec>
            <sec id="sec9">
                <title>Search strategy</title>
                <p>The academic database searches were conducted on 9 May 2025 using Scopus and Web of Science. Grey literature was searched using Google Scholar and Sci-Space, including citation analysis of key articles. There were no study or language limits applied during the information retrieval process. However, the search strategy was limited to the last ten years (2015-2025), to capture developments influenced by the COVID pandemic.</p>
                <p>
The search strategy aimed to identify both peer-reviewed and unpublished research. An initial limited search of Google Scholar and Sci-Space was undertaken to identify relevant articles on the topic. Text words from titles and abstracts of relevant articles and reports, as well as index terms used to describe them, were used to develop the full search strategy. The search strategy, including all identified keywords and index terms, was adapted for each database (refer to extended data 
                    <bold>S1 Appendix: Search terms and keywords</bold>; 
                    <bold>S2 Table: Search strategies</bold>). The reference list of relevant/key papers included in the review was also screened for additional sources. The search strategy terms were checked and verified with team members and NIHR staff before the main searches were conducted, and the final search strategy was reviewed and approved by an information specialist librarian at the University of Southampton.</p>
            </sec>
            <sec id="sec10">
                <title>Data extraction and evidence selection</title>
                <p>Following the search, all identified articles were collated and uploaded into EndNote version 21 
                    <italic toggle="yes">(Clarivate Analytics, PA, USA).</italic> Duplicates were removed using the EndNote duplication identification function, followed by a manual check for consistency. To assess the eligibility criteria and agreement between the three authors (AJBJ, BG, HC), a pilot test of titles and abstracts was conducted on 20 articles.</p>
                <p>As the definitions and descriptors central to the review were developed iteratively, part of the review process involved refining and enhancing these descriptors to ensure clarity and consistency in subsequent screening and extraction. NIHR staff were consulted during this stage to ensure the definitions and descriptors were relevant and appropriate to RDAs.</p>
                <p>All articles were independently reviewed and screened by the reviewers (AJBJ, BG, HC) and notes were recorded in the EndNote library. Any record where the independent reviewer was uncertain, it was discussed with the other reviewers and decisions for inclusion or exclusion were made by consensus. At the full screening stage, if any of the citations were not accessible (e.g., due to a paywall or no full article or report) they were excluded from the review.</p>
                <p>After the final screening, the list of included articles was exported to a Microsoft Excel spreadsheet where the labelling of articles matched the evidence to
                    <list list-type="bullet">
                        <list-item>
                            <label>-</label>
                            <p>Characteristics of the articles (e.g., contributors, title, year, journal, country, source type, study type, field setting, and reporting type)</p>
                        </list-item>
                        <list-item>
                            <label>-</label>
                            <p>Type of RDA reported (e.g., duration, cost, type of award/grant, purpose/focus, and intended outcomes)</p>
                        </list-item>
                        <list-item>
                            <label>-</label>
                            <p>Benefits and challenges (e.g., benefits, potential value and solutions, challenges, barriers to implementation, and research and policy recommendations)</p>
                        </list-item>
                        <list-item>
                            <label>-</label>
                            <p>Recommendations and applicability (e.g., achieve the outcomes they set out to, applicability for funding organisations and research communities, and future considerations)</p>
                        </list-item>
                    </list>
                </p>
                <p>These fields were derived from the articles included in the scoping review and aligned with the five research questions. Data were extracted directly from the included articles into the spreadsheet to avoid returning repeatedly to the full texts and to ensure a consistent and transparent extraction process. Extraction from each full-text article was conducted by AJBJ and verified by other members of the team to ensure accuracy and efficiency in data capture. All evidence was mapped and categorised according to the relevant research questions, and the categorisation was discussed and reviewed at several stages throughout the data extraction process.</p>
                <p>Due to using a scoping review methodology, there was no risk of bias or assessment of the quality of the included articles. The results of the search and the study inclusion process are reported in full in a Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review (PRISMA-ScR) flow diagram (See 
                    <bold>
Figure 1;</bold> extended data: Refer to 
                    <bold>S2 Appendix: PRISMA ScR checklist</bold>)
                    <italic toggle="yes">.</italic>
                </p>
                <p>Institutions, research funders, and professional organisations were explored to complement the scoping review, as these sources provided extensive coverage of the area under review. A list of relevant RFOs was compiled based on previous scoping reviews conducted by members of the team, including reviews focused on topics such as the use of preprints and the capabilities of Artificial Intelligence (AI) in research practices.
                    <sup>
                        <xref ref-type="bibr" rid="ref15">15</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref18">18</xref>
                    </sup> The list of 36 organisations was subsequently verified through additional literature.
                    <sup>
                        <xref ref-type="bibr" rid="ref19">19</xref>
                    </sup> Search results were captured in a separate Microsoft Excel spreadsheet to document evidence from the grey literature, specifically relating to the type, purpose, and scope of awards or grants funded by RFOs. Searches were also complemented by using Microsoft Copilot. The Copilot prompt asked: &#x201c;
                    <italic toggle="yes">What funding organisations give short-term research development awards for capacity building, fund larger studies like seed funding, application development awards, but not focused on career development?&#x201d;</italic> The additional manual search used keyword searches of capacity building, seed funding, and application and development awards.</p>
            </sec>
        </sec>
        <sec id="sec11" sec-type="results">
            <title>Results</title>
            <p>A total of 998 articles were retrieved from the two databases. With 56 duplications and 101 articles taken out, 841 titles and abstracts were screened, followed by 310 full-text articles assessed for eligibility. Of these, 97 articles met the eligibility criteria and were subsequently included in the review. A further, five articles were retrieved from the references of those included articles. A total of 102 articles were included for full extraction. 
                <bold>
Figure 1</bold> (Refer extended data
                <bold>: PRISMA flow diagram</bold>) provides a full account of the records of the identification flow diagram, including the reasons for the excluded articles.</p>
            <sec id="sec12">
                <title>Characteristics of the included articles</title>
                <p>Across the 102 included articles, the number of publications increased steadily from 2015, with a notable rise from 2020 onwards. The highest rise was in 2024 (19/102, 18.6%), followed by 2020 (17/102, 16.6%), and 2022 (15/102, 14.7%), demonstrating a marked upward trend in outputs over this time period.</p>
                <p>Included articles represented a broader geographic distribution; over half originated from the Americas (52/102, 50.9%), followed by Europe (29/102, 28.4%), with smaller contributions from Asia, Australasia, Africa, and the Middle East.</p>
                <p>The articles covered a diverse range of fields, most commonly Health and Care (40/102, 39.2%), followed by Global Health (13/102, 12.7%), and Research and Development (8/102, 7.8%). Other fields also identified included Agriculture, Environmental Sustainability, and Technological Innovation.</p>
                <p>In terms of publication type, half of the included items were original research articles (51/102, 50.0%). A substantial proportion were perspective journal articles (30/102, 29.4%), and a small number of evidence synthesis articles were identified (4/102, 3.9%).</p>
                <p>Over half of the articles reported from a funder perspective (55/102, 53.9%), with a further 42 articles (41.2%) representing the funded perspective (e.g., those that were awarded RDAs). Articles classified as offering a funder perspective were mostly written by RFOs, groups acting on behalf of a funder (e.g., evaluation teams), and multi-stakeholder groups where the dominant viewpoint or purpose reflected funder priorities. Articles classified as the funder perspective were written by researchers or teams who received RDA funding and project partners (e.g., community groups, collaborators) reflecting on their experiences of having received RDA funding. A summary of these characteristics is presented in 
                    <xref ref-type="table" rid="T2">
Table 2</xref>, with full details reported in the supplementary materials (refer to extended data 
                    <bold>
Table S3: Full details of included articles</bold>).</p>
                <table-wrap id="T2" orientation="portrait" position="float">
                    <label>
Table 2. </label>
                    <caption>
                        <title>Summary of the characteristics of the included articles (n=102).</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">Field/Setting (n=102)</italic>
                                    <xref ref-type="table-fn" rid="tfn1">

                                        <italic toggle="yes">*</italic>
                                    </xref>
                                </th>
                                <th align="left" colspan="1" rowspan="1" valign="top">

                                    <italic toggle="yes">N (%)</italic>
</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Academia</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Accelerator Industry</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (5.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Agriculture</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (2.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Counselling</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Education</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (2.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Environmental Science</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Environmental Health</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Environmental Sustainability</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Genetics</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Global Health</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">13 (12.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Health and Care</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">40 (39.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Health Policy</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Innovation Policy</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (3.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Occupational Health and Safety</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Policing</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Public Health</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Research and Development</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (7.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Technological Innovation</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Technology Transfer</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (3.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="2" rowspan="1" valign="top">
                                    <bold>

                                        <italic toggle="yes">Reporting Type (n=102)</italic>
</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Funder Perspective</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">55 (53.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Funded Perspective</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">42 (41.2)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Other</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="2" rowspan="1" valign="top">
                                    <bold>

                                        <italic toggle="yes">Year of publication: (n=102)</italic>
</bold>
                                    <xref ref-type="table-fn" rid="tfn1">

                                        <bold>

                                            <italic toggle="yes">*</italic>
</bold>
                                    </xref>
                                </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2015</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (3.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2016</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2017</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">9 (8.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2018</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (2.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2019</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (7.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2020</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">17 (16.6)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2021</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (5.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2022</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">15 (14.7)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2023</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (7.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2024</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">19 (18.6)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2025</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (7.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="2" rowspan="1" valign="top">
                                    <bold>

                                        <italic toggle="yes">Country by region: (n=102)</italic>
</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Americas**</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">52(50.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Asia</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">6 (5.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Australasia</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">3 (2.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">East Africa</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Europe</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">29 (28.4)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Global***</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Middle East</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">South Africa</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">West Africa</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="2" rowspan="1" valign="top">
                                    <bold>

                                        <italic toggle="yes">Article type: (n=102)</italic>
</bold>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Chapter book</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">2 (1.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Conference Proceeding</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Journal Evidence &#x2013; evidence synthesis</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">4 (3.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Journal &#x2013; Original Research</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">51 (50.0)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Journal &#x2013; Perspective****</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">30 (29.4)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Reports *****</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">8 (7.8)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Thesis</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">5 (4.9)</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Webpage</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1 (0.9)</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn-group content-type="footnotes">
                            <fn id="tfn1">
                                <label>*</label>
                                <p>Percentages fall between 99%-102% due to the decimal point.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
            <sec id="sec13">
                <title>Summarising the evidence</title>
                <p>
As the review progressed, the evidence revealed a wider range of award purposes, outcomes, and RDA types than were originally anticipated. To ensure rigour, transparency, and relevance, the 
                    <italic toggle="yes">purpose and intended outcomes criterion</italic> used during screening was iteratively expanded. This refinement allowed for the inclusion of awards more accurately aligned with the diverse nature of activities supported under these funding schemes. The same iterative process was applied to the variations and types of RDAs, enabling a clearer and more comprehensive description of the different award/grant models reported in the current literature. This structured approach enhanced the precision of the eligibility framework and strengthened the consistency of decision-making throughout the conduct, analysis, and interpretation of the findings. 
                    <xref ref-type="table" rid="T3">
Table 3</xref> shows how the original descriptions were expanded into a more detailed, evidence-informed set of descriptors. These enhancements enabled the review to accurately capture the breadth and complexity of RDA mechanisms internationally. Each article was reassessed against the updated criteria to ensure full alignment with the refined framework, including explicit consideration of international variation in research contexts and terminology. This included attention to differences in how RDAs are labelled and conceptualised globally, such as the use of terms like &#x2018;incubator&#x2019; to describe RDAs in some settings.</p>
                <table-wrap id="T3" orientation="portrait" position="float">
                    <label>
Table 3. </label>
                    <caption>
                        <title>Original and revised inclusion framework.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Inclusion criteria</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Original description</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Enhanced description based on the evidence</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Purpose and intended outcomes (meet at least one criterion)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <p>

                                        <list list-type="bullet">
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Building collaboration/networking</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research capacity and partnerships</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Supporting translation of knowledge</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Stimulate the research community and build research readiness</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Lay the foundations for future larger and longer supported awards</p>
                                            </list-item>
                                        </list>
                                    </p>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <p>

                                        <list list-type="bullet">
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Building collaboration/networking (including international perspective)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Community involvement to reduce disparities (across health and social care)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research capacity and partnerships (including Equitable partnerships)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Supporting translation of knowledge</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Stimulate the research community and build research readiness (including Community-Based Participatory Research (CBPR))</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Applicability and use of novel methods (e.g., co-production, platforms, feasibility of implementation/development of an intervention)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Lay the foundations for future larger and longer supported awards (including Application Development Awards (ADAs))</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Innovation technologies and development</p>
                                            </list-item>
                                        </list>
                                    </p>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Variations and types of RDAs (meet at least one criterion)</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <p>

                                        <list list-type="bullet">
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Seed Funding</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Catalyst Awards</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Pump Prime Funding</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research Collaboration Funding</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Development Awards (specially labelled as such)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Programme Development Grants</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Acceleration Awards</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research capacity Awards</p>
                                            </list-item>
                                        </list>
                                    </p>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <p>

                                        <list list-type="bullet">
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Seed Funding (including innovation awards/grants)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Catalyst Awards/Grants</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Pump Prime Funding</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research Collaboration Funding</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Development Awards/Grants (including Programme Development Awards/Grants)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Acceleration Awards/Grants</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research capacity Awards/Grants</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Application Development Awards (ADA)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Funding Development Awards/Grants</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Research Partnerships (including partnership grants)</p>
                                            </list-item>
                                            <list-item>
                                                <label>&#x2022;</label>
                                                <p>Incubators
                                                    <xref ref-type="table-fn" rid="tfn2">*</xref>
                                                </p>
                                            </list-item>
                                        </list>
                                    </p>
</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Duration of the award</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to 18 months</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to two years</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">Amount of award</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to &#x00a3;200,000</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">Up to &#x00a3;200,000</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn-group content-type="footnotes">
                            <fn id="tfn2">
                                <label>*</label>
                                <p>There were notable global differences in terms of definition and interpretation of the use of the term &#x201c;incubator&#x201d; as a term for Research Development Awards. Each article was assessed on eligibility to determine its inclusion into the review.</p>
                            </fn>
                        </fn-group>
                    </table-wrap-foot>
                </table-wrap>
                <p>The evidence found in the database searches and grey literature were grouped based on the five research questions under three overarching theme areas, as illustrated in 
                    <bold>
Figure 2 (</bold>Refer to 
                    <bold>extended data repository)</bold>.
                    <list list-type="bullet">
                        <list-item>
                            <label>-</label>
                            <p>The purpose and context of RDAs:</p>
                            <list list-type="bullet">
                                <list-item>
                                    <label>&#x25aa;</label>
                                    <p>RQ1 - How does the evidence describe the purpose of RDAs (also known as seed funding, prime and catalyst funding)?</p>
                                </list-item>
                                <list-item>
                                    <label>&#x25aa;</label>
                                    <p>RQ3 - Does the evidence suggest RDAs are best suited in a particular context?</p>
                                </list-item>
                            </list>
                        </list-item>
                        <list-item>
                            <label>-</label>
                            <p>The challenges and benefits of RDAs:</p>
                            <list list-type="bullet">
                                <list-item>
                                    <label>&#x25aa;</label>
                                    <p>RQ2 - How does the evidence describe the intended outcomes, benefits, and challenges of RDAs?</p>
                                </list-item>
                            </list>
                        </list-item>
                        <list-item>
                            <label>-</label>
                            <p>Achieving the intended outcomes of RDAs:</p>
                            <list list-type="bullet">
                                <list-item>
                                    <label>&#x25aa;</label>
                                    <p>RQ 4 - Does the evidence suggest any specific outcomes (e.g. building relationships) that RDAs are particularly well-suited to achieving?</p>
                                </list-item>
                                <list-item>
                                    <label>&#x25aa;</label>
                                    <p>RQ5 - To what extent does the evidence suggest that RDAs achieve the outcomes they set out to?</p>
                                </list-item>
                            </list>
                        </list-item>
                    </list>
</p>
                <p>Across the themed areas, there was considerable variation in how RDAs were conceptualised, implemented, and reported. The distribution of articles did not easily map into single standalone themes, they spanned multiple areas of focus, reflecting the overlapping and multidimensional nature of RDAs. Similarly, a substantial proportion of articles reported more than one viewpoint, often combining reflections on what was being reported with broader system-level insights drawn from both the funder and funded positions. This overlap underscores the complexity of RDA mechanisms and highlights the interconnected roles of stakeholders involved in their design, delivery, and implementation.</p>
                <p>To strengthen the analysis of the funder perspective, we also reviewed publicly available information from funding and professional organisations. These sources provided additional insight into how RDAs are conceptualised, prioritised, and operationalised within funding systems.</p>
                <p>The sections below synthesise evidence from across the academic literature and organisational sources, structured around the thematic areas illustrated in 
                    <bold>
Figure 2 ((</bold>Refer to 
                    <bold>extended data repository)</bold>, beginning with the purpose and context of RDAs.</p>
            </sec>
            <sec id="sec14">
                <title>The purpose and context of RDAs (RQ1 and RQ3)</title>
                <p>This section examines how the evidence describes the purpose of RDAs (RQ1) and the contexts in which they are considered most appropriate and effective (RQ3), including the settings, conditions, and funding environments in which RDAs are deployed within the wider funding landscape. RDAs were consistently described in the evidence as flexible, early-stage funding mechanisms designed to stimulate collaboration, strengthen research capacity, and catalyse innovation across a wide range of research settings. Although the terminology varied between countries, such as seed funding, catalyst awards, pump-priming, development grants, and application development awards, the core purpose remained broadly aligned.
                    <sup>
                        <xref ref-type="bibr" rid="ref20">20</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref36">36</xref>
                    </sup> RDAs were primarily used to build the foundations necessary for more substantive, longer-term research programmes by supporting exploratory work, partnership development, and the generation of preliminary data or proof-of-concept.
                    <sup>
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref32">32</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref59">59</xref>
                    </sup>
                </p>
                <p>A dominant theme in the evidence was the role of RDAs in building research capacity (32 references).
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref56">56</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref76">76</xref>
                    </sup> This included strengthening institutional readiness, providing opportunities for training and mentoring, supporting Early Career Researchers (ECRs), and enabling interdisciplinary teams to establish skills for future research. Much of this capacity strengthening was explicitly linked to preparing for larger grants, fostering research communities, and supporting methodological development.</p>
                <p>Other commonly identified purposes were fostering collaboration (32 references) and catalysing innovation and research impact (30 references).
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref20">20</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref35">35</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref70">70</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref96">96</xref>
                    </sup> RDAs were frequently positioned as mechanisms to create or deepen relationships across academic, community, and policy settings. This included supporting cross-sector partnerships, multi-country collaborations (particularly in global health), and community-academic partnerships that required protected time and resources to establish trust, shared goals, and governance structures.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref99">99</xref>
                    </sup> RDAs were viewed as important for addressing structural barriers to collaboration, such as the lack of time, funding, or organisational support for partnership development and co-production.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref104">104</xref>
                    </sup> RDAs enable pilot studies, feasibility assessments, and high-risk exploratory work that could be considered too uncertain for larger funding opportunities. In this context, RDAs were seen as a pathway to help reduce the risk of innovative ideas and accelerate the translation of discoveries into research policy or practice.</p>
                <p>Community-Based Participatory Research (CBPR) featured prominently across the included literature as a guiding framework for RDAs that prioritise equitable partnership working, power-sharing, and capacity building. CBPR-focused RDAs were consistently described as enabling early-stage relationship development between academic and community partners, supporting co-learning, shared agenda-setting, and trust-building prior to the pursuit of larger research grants.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref30">30</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>
                    </sup> Several studies emphasised that seed or catalyst funding alone was insufficient, and that CBPR-aligned RDAs were most effective when combined with structured training, mentoring, technical assistance, and adequate time horizons to support the maturity of partnerships and sustainability.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>
                    </sup> Collectively, this literature highlights CBPR as both a purpose and an outcome of RDAs, particularly within community-engaged, public health, and global health contexts, while also illustrating the tensions that arise when short-term funding models are used to support inherently relational and long-term approaches to research development.
                    <sup>
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup>
                </p>
                <p>The evidence highlighted four broad areas in the context of where RDAs can be most suited.
                    <list list-type="order">
                        <list-item>
                            <label>1.</label>
                            <p>They are particularly valuable in resource-constrained environments, where flexible, short-term awards enabled teams to address technological, workforce, or infrastructure limitations. These awards often allowed progress using existing resources, supported local knowledge generation, and strengthened evidence-informed decision-making in settings lacking sustained research investment.
                                <sup>
                                    <xref ref-type="bibr" rid="ref9">9</xref>,
                                    <xref ref-type="bibr" rid="ref25">25</xref>,
                                    <xref ref-type="bibr" rid="ref27">27</xref>,
                                    <xref ref-type="bibr" rid="ref28">28</xref>,
                                    <xref ref-type="bibr" rid="ref31">31</xref>,
                                    <xref ref-type="bibr" rid="ref38">38</xref>,
                                    <xref ref-type="bibr" rid="ref41">41</xref>,
                                    <xref ref-type="bibr" rid="ref44">44</xref>,
                                    <xref ref-type="bibr" rid="ref48">48</xref>,
                                    <xref ref-type="bibr" rid="ref52">52</xref>,
                                    <xref ref-type="bibr" rid="ref54">54</xref>,
                                    <xref ref-type="bibr" rid="ref58">58</xref>,
                                    <xref ref-type="bibr" rid="ref61">61</xref>,
                                    <xref ref-type="bibr" rid="ref69">69</xref>,
                                    <xref ref-type="bibr" rid="ref70">70</xref>,
                                    <xref ref-type="bibr" rid="ref77">77</xref>,
                                    <xref ref-type="bibr" rid="ref85">85</xref>,
                                    <xref ref-type="bibr" rid="ref88">88</xref>,
                                    <xref ref-type="bibr" rid="ref93">93</xref>,
                                    <xref ref-type="bibr" rid="ref94">94</xref>,
                                    <xref ref-type="bibr" rid="ref100">100</xref>,
                                    <xref ref-type="bibr" rid="ref107">107</xref>
                                </sup>
                            </p>
                        </list-item>
                        <list-item>
                            <label>2.</label>
                            <p>They were identified as effective in time sensitive or emergency contexts. Their short duration and flexible structure enabled rapid insight generation during epidemics, crises, or urgent policy situations when traditional research funding mechanisms were too slow to respond.
                                <sup>
                                    <xref ref-type="bibr" rid="ref20">20</xref>,
                                    <xref ref-type="bibr" rid="ref25">25</xref>,
                                    <xref ref-type="bibr" rid="ref27">27</xref>,
                                    <xref ref-type="bibr" rid="ref30">30</xref>,
                                    <xref ref-type="bibr" rid="ref31">31</xref>,
                                    <xref ref-type="bibr" rid="ref41">41</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref46">46</xref>,
                                    <xref ref-type="bibr" rid="ref49">49</xref>,
                                    <xref ref-type="bibr" rid="ref51">51</xref>,
                                    <xref ref-type="bibr" rid="ref53">53</xref>,
                                    <xref ref-type="bibr" rid="ref55">55</xref>,
                                    <xref ref-type="bibr" rid="ref61">61</xref>,
                                    <xref ref-type="bibr" rid="ref62">62</xref>,
                                    <xref ref-type="bibr" rid="ref64">64</xref>,
                                    <xref ref-type="bibr" rid="ref65">65</xref>,
                                    <xref ref-type="bibr" rid="ref67">67</xref>,
                                    <xref ref-type="bibr" rid="ref69">69</xref>,
                                    <xref ref-type="bibr" rid="ref70">70</xref>,
                                    <xref ref-type="bibr" rid="ref76">76</xref>,
                                    <xref ref-type="bibr" rid="ref88">88</xref>,
                                    <xref ref-type="bibr" rid="ref89">89</xref>,
                                    <xref ref-type="bibr" rid="ref95">95</xref>,
                                    <xref ref-type="bibr" rid="ref97">97</xref>,
                                    <xref ref-type="bibr" rid="ref99">99</xref>,
                                    <xref ref-type="bibr" rid="ref100">100</xref>,
                                    <xref ref-type="bibr" rid="ref102">102</xref>,
                                    <xref ref-type="bibr" rid="ref104">104</xref>,
                                    <xref ref-type="bibr" rid="ref107">107</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref113">113</xref>
                                </sup>
                            </p>
                        </list-item>
                        <list-item>
                            <label>3.</label>
                            <p>They were well-suited to capacity building and applied learning environments. When combined with mentoring and training, RDAs supported teams to develop new analytical, methodological, and collaborative capabilities within real-world settings. This included improving data literacy, supporting ECRs, and building institutional capacity for evidence application.
                                <sup>
                                    <xref ref-type="bibr" rid="ref7">7</xref>,
                                    <xref ref-type="bibr" rid="ref8">8</xref>,
                                    <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref25">25</xref>,
                                    <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref29">29</xref>,
                                    <xref ref-type="bibr" rid="ref31">31</xref>,
                                    <xref ref-type="bibr" rid="ref32">32</xref>,
                                    <xref ref-type="bibr" rid="ref40">40</xref>,
                                    <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref46">46</xref>,
                                    <xref ref-type="bibr" rid="ref50">50</xref>,
                                    <xref ref-type="bibr" rid="ref54">54</xref>,
                                    <xref ref-type="bibr" rid="ref55">55</xref>,
                                    <xref ref-type="bibr" rid="ref59">59</xref>,
                                    <xref ref-type="bibr" rid="ref60">60</xref>,
                                    <xref ref-type="bibr" rid="ref65">65</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref67">67</xref>,
                                    <xref ref-type="bibr" rid="ref69">69</xref>,
                                    <xref ref-type="bibr" rid="ref72">72</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref76">76</xref>,
                                    <xref ref-type="bibr" rid="ref79">79</xref>,
                                    <xref ref-type="bibr" rid="ref80">80</xref>,
                                    <xref ref-type="bibr" rid="ref82">82</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref84">84</xref>,
                                    <xref ref-type="bibr" rid="ref88">88</xref>,
                                    <xref ref-type="bibr" rid="ref91">91</xref>,
                                    <xref ref-type="bibr" rid="ref93">93</xref>,
                                    <xref ref-type="bibr" rid="ref96">96</xref>,
                                    <xref ref-type="bibr" rid="ref99">99</xref>,
                                    <xref ref-type="bibr" rid="ref109">109</xref>,
                                    <xref ref-type="bibr" rid="ref114">114</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref116">116</xref>
                                </sup>
                            </p>
                        </list-item>
                        <list-item>
                            <label>4.</label>
                            <p>
They were frequently used in collaborative, multidisciplinary, and multi-sectoral contexts. Their flexibility enabled diverse stakeholders, such as academics, practitioners, community groups, and policymakers, to co-produce research questions, share perspectives, and develop joint solutions.
                                <sup>
                                    <xref ref-type="bibr" rid="ref7">7</xref>,
                                    <xref ref-type="bibr" rid="ref9">9</xref>,
                                    <xref ref-type="bibr" rid="ref24">24</xref>,
                                    <xref ref-type="bibr" rid="ref27">27</xref>,
                                    <xref ref-type="bibr" rid="ref31">31</xref>,
                                    <xref ref-type="bibr" rid="ref42">42</xref>,
                                    <xref ref-type="bibr" rid="ref44">44</xref>,
                                    <xref ref-type="bibr" rid="ref46">46</xref>,
                                    <xref ref-type="bibr" rid="ref47">47</xref>,
                                    <xref ref-type="bibr" rid="ref51">51</xref>,
                                    <xref ref-type="bibr" rid="ref59">59</xref>,
                                    <xref ref-type="bibr" rid="ref61">61</xref>,
                                    <xref ref-type="bibr" rid="ref64">64</xref>,
                                    <xref ref-type="bibr" rid="ref67">67</xref>,
                                    <xref ref-type="bibr" rid="ref69">69</xref>,
                                    <xref ref-type="bibr" rid="ref72">72</xref>,
                                    <xref ref-type="bibr" rid="ref74">74</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref76">76</xref>,
                                    <xref ref-type="bibr" rid="ref79">79</xref>,
                                    <xref ref-type="bibr" rid="ref93">93</xref>,
                                    <xref ref-type="bibr" rid="ref96">96</xref>,
                                    <xref ref-type="bibr" rid="ref99">99</xref>,
                                    <xref ref-type="bibr" rid="ref102">102</xref>,
                                    <xref ref-type="bibr" rid="ref107">107</xref>,
                                    <xref ref-type="bibr" rid="ref112">112</xref>&#x2013;
                                    <xref ref-type="bibr" rid="ref114">114</xref>
                                </sup>
                            </p>
                        </list-item>
                    </list>
                </p>
                <p>
Overall, the evidence demonstrates that RDAs occupy a distinct and important role within the research funding landscape (see 
                    <xref ref-type="table" rid="T4">
Table 4</xref>). Their value lies not only in providing small-scale, early-stage funding, but in enabling collaboration, nurturing inclusive and equitable partnerships, building foundational capacity, supporting methodological innovation, and responding to contextual challenges or opportunities.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref72">72</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref82">82</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref88">88</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref103">103</xref>,
                        <xref ref-type="bibr" rid="ref104">104</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>,
                        <xref ref-type="bibr" rid="ref110">110</xref>,
                        <xref ref-type="bibr" rid="ref111">111</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>,
                        <xref ref-type="bibr" rid="ref118">118</xref>
                    </sup> RDAs appear to be most effective where flexibility, rapid mobilisation, and relational work are critical, particularly in resource-limited settings, interdisciplinary environments, and time-sensitive contexts.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref42">42</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref91">91</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref98">98</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref112">112</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> These findings illustrate the diverse and strategic purpose of RDAs and highlight their significance as a complementary mechanism alongside larger-scale research funding opportunities.</p>
                <table-wrap id="T4" orientation="portrait" position="float">
                    <label>
Table 4. </label>
                    <caption>
                        <title>Key concepts, themes, and statements associated with the purpose and context of RDAs.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Key themes</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Statements</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No. refs</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="7" valign="middle">
                                    <bold>How does the evidence describe the purpose of the RDAs?</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Flexible, Responsive Funding:</bold> Small-scale, short-duration awards with staged models (catalyst, development, acceleration) for inception, piloting and scaling, participatory evaluation to inform future funding approaches
                                    <sup>
                                        <xref ref-type="bibr" rid="ref126">126</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">54</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Enable Translation and Impact:</bold> Align research with policy/practice and societal priorities, support knowledge exchange and real-world application, including dissemination and stakeholder engagement, facilitate institutional change by refining policies and infrastructure, bridge the gap between theory and practice
                                    <sup>
                                        <xref ref-type="bibr" rid="ref7">7</xref>,
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref28">28</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref34">34</xref>,
                                        <xref ref-type="bibr" rid="ref37">37</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref46">46</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref53">53</xref>,
                                        <xref ref-type="bibr" rid="ref56">56</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref61">61</xref>,
                                        <xref ref-type="bibr" rid="ref63">63</xref>,
                                        <xref ref-type="bibr" rid="ref65">65</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref72">72</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref89">89</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref95">95</xref>,
                                        <xref ref-type="bibr" rid="ref115">115</xref>,
                                        <xref ref-type="bibr" rid="ref117">117</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">37</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Build Research Capacity</bold>: Support early-career researchers and interdisciplinary teams, training, mentorship, institutional readiness, stimulate research communities for larger, longer-term grants
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref9">9</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>,
                                        <xref ref-type="bibr" rid="ref46">46</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref51">51</xref>,
                                        <xref ref-type="bibr" rid="ref56">56</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref76">76</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">32</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Foster Collaboration</bold>: Enable academic-community partnerships, interdisciplinary and cross-sector collaborations, and address structural barriers such as lack of time or resources for partnership development, including grant writing
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref61">61</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref65">65</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref70">70</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref75">75</xref>,
                                        <xref ref-type="bibr" rid="ref77">77</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref82">82</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">32</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Catalyse Research Impact and innovation</bold>: Seed/catalyst funding for pilot studies, proof-of-concept, high-risk innovative ideas, feasibility studies, de-risking research for future investment to explore innovative and exploratory research ideas, bridge the gap between discovery and commercialisation
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref28">28</xref>,
                                        <xref ref-type="bibr" rid="ref35">35</xref>,
                                        <xref ref-type="bibr" rid="ref37">37</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref83">83</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref93">93</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">31</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Address Equity and Inclusion</bold>: Promote equitable partnerships, diversity, and inclusion in research, co-production of research to reduce disparities, promoted shared ownership to create more inclusive scientific solutions
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref9">9</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref33">33</xref>,
                                        <xref ref-type="bibr" rid="ref35">35</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref62">62</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>,
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref70">70</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref75">75</xref>,
                                        <xref ref-type="bibr" rid="ref77">77</xref>,
                                        <xref ref-type="bibr" rid="ref78">78</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref99">99</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref101">101</xref>,
                                        <xref ref-type="bibr" rid="ref104">104</xref>,
                                        <xref ref-type="bibr" rid="ref106">106</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>,
                                        <xref ref-type="bibr" rid="ref116">116</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">29</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Leverage Follow-on Funding</bold>: Attract larger grants and investments by acting as an initial funding source, fostering and driving innovation opportunities
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref56">56</xref>,
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref75">75</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref83">83</xref>,
                                        <xref ref-type="bibr" rid="ref85">85</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref95">95</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref98">98</xref>,
                                        <xref ref-type="bibr" rid="ref104">104</xref>,
                                        <xref ref-type="bibr" rid="ref105">105</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>,
                                        <xref ref-type="bibr" rid="ref111">111</xref>,
                                        <xref ref-type="bibr" rid="ref115">115</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">26</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="4" valign="middle">
                                    <bold>Does the evidence suggest RDAs are best suited in a particular context?</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Resource-constrained Environments</bold>: RDAs in low-resource systems offer actionable insights from existing data, overcoming technological and staffing challenges to support evidence-based decisions, and promoting equitable, efficient health and care
                                    <sup>
                                        <xref ref-type="bibr" rid="ref9">9</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref28">28</xref>,
                                        <xref ref-type="bibr" rid="ref30">30</xref>,
                                        <xref ref-type="bibr" rid="ref33">33</xref>,
                                        <xref ref-type="bibr" rid="ref35">35</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref59">59</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref62">62</xref>,
                                        <xref ref-type="bibr" rid="ref63">63</xref>,
                                        <xref ref-type="bibr" rid="ref65">65</xref>,
                                        <xref ref-type="bibr" rid="ref67">67</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref78">78</xref>,
                                        <xref ref-type="bibr" rid="ref80">80</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref83">83</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>,
                                        <xref ref-type="bibr" rid="ref102">102</xref>,
                                        <xref ref-type="bibr" rid="ref103">103</xref>,
                                        <xref ref-type="bibr" rid="ref105">105</xref>,
                                        <xref ref-type="bibr" rid="ref106">106</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>,
                                        <xref ref-type="bibr" rid="ref112">112</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref114">114</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">37</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Time-sensitive Decision-making
</bold>: RDAs are valuable in emergencies or epidemic responses for providing rapid insights to inform policy and operational decisions, especially when traditional research is too slow. They offer quick contextual analysis and synthesis to mitigate risks and improve outcomes
                                    <sup>
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref45">45</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref53">53</xref>,
                                        <xref ref-type="bibr" rid="ref54">54</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref61">61</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref89">89</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref95">95</xref>,
                                        <xref ref-type="bibr" rid="ref109">109</xref>,
                                        <xref ref-type="bibr" rid="ref110">110</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">23</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Capacity-building and Applied Learning:</bold> RDAs, when combined with training and mentoring, effectively build local analytical capacity and data literacy. This approach facilitates applied learning in real-world contexts, leading to actionable outputs and promoting institutional practice for evidence-based decision-making
                                    <sup>
                                        <xref ref-type="bibr" rid="ref7">7</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref75">75</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref99">99</xref>,
                                        <xref ref-type="bibr" rid="ref107">107</xref>,
                                        <xref ref-type="bibr" rid="ref117">117</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">10</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Collaborative and Multi-sectoral Environments:</bold> RDAs work well where stakeholder engagement and co-production are prioritised, enabling rapid synthesis of diverse perspectives, offering flexibility and integration that is aligned with shared goals, strengthening networks and enhancing sustainability
                                    <sup>
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref38">38</xref>,
                                        <xref ref-type="bibr" rid="ref42">42</xref>,
                                        <xref ref-type="bibr" rid="ref104">104</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">5</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec id="sec15">
                <title>The benefits and challenges of RDAs (RQ2)</title>
                <p>This section examines how the evidence describes the benefits and challenges associated with RDAs (RQ2), focusing on their intended value, potential contributions, and the barriers and limitations that influence their design, implementation, and effectiveness in practice. The evidence indicated that RDAs generate considerable value by building capacity, initiating collaboration, fostering equity, and catalysing innovation.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref42">42</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref56">56</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref68">68</xref>,
                        <xref ref-type="bibr" rid="ref71">71</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref82">82</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>
                    </sup> However, these benefits are highly dependent on project design, implementation context, funding flexibility, and administrative support. From the literature, RDAs were consistently described as mechanisms that create value by enabling early-stage research activity that would otherwise be challenging to support through traditional funding approaches, while also presenting challenges associated with their short duration, limited scale, and issues in evaluating longer-term impact (see 
                    <xref ref-type="table" rid="T5">
Table 5</xref>).</p>
                <table-wrap id="T5" orientation="portrait" position="float">
                    <label>
Table 5. </label>
                    <caption>
                        <title>Key concepts, benefits and challenges of RDAs.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Key themes</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Statements</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No. refs</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="7" valign="middle">
                                    <bold>What are the benefits associated with RDAs?</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Capacity Building:</bold> Structured training, mentorship, and workplace learning enhance research skills and methodological expertise. This improves capacity for equitable, community-engaged research and strengthens early-career researchers and institutional capacity
                                    <sup>
                                        <xref ref-type="bibr" rid="ref9">9</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref42">42</xref>,
                                        <xref ref-type="bibr" rid="ref44">44</xref>,
                                        <xref ref-type="bibr" rid="ref45">45</xref>,
                                        <xref ref-type="bibr" rid="ref54">54</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref56">56</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref65">65</xref>,
                                        <xref ref-type="bibr" rid="ref67">67</xref>,
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref80">80</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">28</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Networking/Collaboration:</bold> Catalyst funding successfully initiates multi-country partnerships and consortia by fostering collaborations across disciplines and sectors, building LMIC&#x2013;HIC partnerships, strengthening community&#x2013;academic partnerships, and accelerating pipelines for future funded calls
                                    <sup>
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref65">65</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref75">75</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref101">101</xref>,
                                        <xref ref-type="bibr" rid="ref107">107</xref>,
                                        <xref ref-type="bibr" rid="ref111">111</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">22</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Equitable Partnerships:</bold> Promoting equitable partnerships, diversity, and inclusion in research collaborations through dedicated seed funding to establish diverse partnerships and counter structural inequities in grant decision-making. Guidance is offered for equitable participation. Evidence shows that RDAs enabled co-learning and equitable engagement in award development
                                    <sup>
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref78">78</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">19</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Sustainability/Long-term Support:</bold> Subsequent major awards and additional grants secured through initial seed funding systematically leverage follow-on investment and sustain partnerships. This continuity prevents collaboration fragmentation, allows scaling of successful interventions, fosters trust, enhances institutional readiness, and increases the translation of research into long-term policy and practice impact
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref107">107</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">13</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Impact/Policy Engagement:</bold> Create opportunities for research to influence policy and practice by funding activities that strengthen connections between researchers, decision-makers, and practitioners; awards enable co-design of research questions with policy stakeholders, support the production of policy briefs, and facilitate engagement during critical windows for decision-making; accelerate the uptake of evidence into policy and practice
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref28">28</xref>,
                                        <xref ref-type="bibr" rid="ref34">34</xref>,
                                        <xref ref-type="bibr" rid="ref37">37</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref83">83</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref117">117</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">11</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Flexibility/Staged Funding:</bold> Enables iterative development, supports inception phases for co-design, and accelerates impact pathways by bridging gaps between initial concept work and larger-scale implementation. This agility reduces risk, fosters innovation, and ensures that promising collaborations can evolve in alignment with changing policy and practice contexts
                                    <sup>
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref35">35</xref>,
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref53">53</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref85">85</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">10</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Funding Scale/Duration:</bold> Offer adaptable, phased funding to allow projects to evolve in response to emerging opportunities and stakeholder needs, support co-design and rapid prototyping, and reduce risk. This staged approach fosters innovation, accelerates impact pathways, and strengthens collaborative research
                                    <sup>
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref90">90</xref>,
                                        <xref ref-type="bibr" rid="ref113">113</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">8</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="5" valign="middle">
                                    <bold>What are the challenges associated with RDAs?</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Short Duration and Limited Funding:</bold> Short, time-limited, and small-scale awards (e.g., 6&#x2013;12 months) make sustainability difficult, often requiring follow-on funding. Limited funds constrain activities like public involvement, reducing depth and diversity of engagement. These limitations in scope and time also challenge meaningful engagement, partnership building, and long-term planning
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref29">29</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref34">34</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref44">44</xref>,
                                        <xref ref-type="bibr" rid="ref45">45</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref78">78</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref90">90</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref96">96</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>,
                                        <xref ref-type="bibr" rid="ref111">111</xref>,
                                        <xref ref-type="bibr" rid="ref117">117</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">55</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Measuring Impact Evaluation and Sustainability</bold>: Metrics often fail to capture long-term impact and systemic change. Projects face challenges in sustaining momentum, outputs (like tools or networks), and demonstrating return on investment after initial funding ends. Lack of follow-on funding for scaling is a recurring issue, and success metrics often don't align well with the nature of RDAs
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref34">34</xref>,
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref67">67</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref96">96</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">40</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Partnership Difficulties:</bold> Challenges in forming and maintaining equitable partnerships, especially in international or interdisciplinary contexts; Issues include power imbalances and unclear roles; Evidence gaps in long-term impact and partnership quality
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref44">44</xref>,
                                        <xref ref-type="bibr" rid="ref45">45</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref78">78</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref85">85</xref>,
                                        <xref ref-type="bibr" rid="ref90">90</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref111">111</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">36</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Cultural and Logistical Issues:</bold> Interdisciplinary and community-engaged research requires time for trust-building and alignment of priorities; Academic reward systems rarely value partnership-building or co-production; Limited infrastructure, staff turnover, and inadequate technical support in some settings reduce the effectiveness of capacity-building efforts
                                    <sup>
                                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref32">32</xref>,
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref45">45</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>,
                                        <xref ref-type="bibr" rid="ref118">118</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">35</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Administrative and Structural Barriers:</bold> Complex institutional requirements (policies, application processes, reporting requirements, lack of funding flexibility, bureaucratic delays) impede project flexibility and implementation. In global health, power imbalances and inequitable funding structures between high-income and LMIC partners remain
                                    <sup>
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref31">31</xref>,
                                        <xref ref-type="bibr" rid="ref36">36</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref50">50</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref53">53</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref67">67</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref84">84</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref96">96</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">27</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>Capacity building was highlighted in the evidence as a key consideration, where RDAs were widely reported to strengthen individual teams, and institutional research capacity through structured training, mentorship, and workplace learning.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref42">42</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref56">56</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref68">68</xref>,
                        <xref ref-type="bibr" rid="ref71">71</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref82">82</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>
                    </sup> Closely, related was the role of RDAs in initiating and strengthening collaborations and networks.
                    <sup>
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref32">32</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref81">81</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref101">101</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref111">111</xref>
                    </sup> These benefits were especially evidenced in interdisciplinary and community-engaged research contexts, where RDAs supported skills development for equitable partnership working, methods, and applied research.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref65">65</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref70">70</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref78">78</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref97">97</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref101">101</xref>,
                        <xref ref-type="bibr" rid="ref104">104</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref106">106</xref>,
                        <xref ref-type="bibr" rid="ref114">114</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> At the same time, RDAs acted as effective catalysts for forming new partnerships across disciplines, sectors, and geographies, including community-academic collaborations, multi-country consortia, and Low and Middle Income Countries &#x2013; High Income Countries (LMIC-HIC) partnerships.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref59">59</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref95">95</xref>,
                        <xref ref-type="bibr" rid="ref97">97</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref104">104</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup> By providing protected time and early-stage resources, RDAs enable partners to build trust, clarify shared objectives, and establish governance arrangements, addressing common structural barriers such as limited time, resources, and funding for partnership development. For ECRs and research teams operating in resource constrained environments, RDAs were frequently described as a critical entry point into longer-term collaborative opportunities that later progressed to funded research.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref59">59</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>,
                        <xref ref-type="bibr" rid="ref118">118</xref>
                    </sup>
                </p>
                <p>Overall, flexible funding structures such as RDAs allow teams to refine ideas, methods, and partnerships before committing to larger-scale investment. This agility was seen as particularly valuable for innovation, high-risk research, and work operating at the intersection of research, policy, and practice.
                    <sup>
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref30">30</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref32">32</xref>,
                        <xref ref-type="bibr" rid="ref34">34</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref49">49</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref56">56</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref71">71</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref102">102</xref>,
                        <xref ref-type="bibr" rid="ref103">103</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> RDAs are also shown to promote more inclusive and equitable research practices by resourcing early engagement, co-production, and power sharing, particularly in community-engaged and global research contexts.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref72">72</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref97">97</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref102">102</xref>,
                        <xref ref-type="bibr" rid="ref111">111</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> By reducing the barriers to early-stage innovation and enabling proof-of-concept work, RDAs create pathways to larger grants, sustained partnerships, and longer-term policy and practice impact, positioning them as a strategically important component of research funding portfolios that add value not through scale but through flexibility, relational work, and their ability to unlock future investment and impact.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref35">35</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup>
                </p>
                <p>
Despite these benefits, the evidence consistently identified significant challenges associated with RDAs. The most frequently reported challenge was short duration and limited funding.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref91">91</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref98">98</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref102">102</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>,
                        <xref ref-type="bibr" rid="ref108">108</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref115">115</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref118">118</xref>
                    </sup> Time limited awards, often ranging from six to twelve months, were widely viewed as insufficient for establishing meaningful partnerships, conducting robust engagement activities, or delivering sustained outcomes.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> Limited funding further constrained the scope of work, particularly for activities such as public and community engagement, international collaboration, and infrastructure development.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref34">34</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref85">85</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref104">104</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup> As a result, many RDA funded projects were heavily dependent on securing follow-on funding to sustain research-related activities.
                    <sup>
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>
                    </sup> A further major challenge concerned measuring impact, evaluation, and sustainability.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref32">32</xref>,
                        <xref ref-type="bibr" rid="ref34">34</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref81">81</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref88">88</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref97">97</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref118">118</xref>
                    </sup> Traditional performance metrics, such as publications or short-term outputs, were frequently misaligned with the developmental, relational, and long-term aims of RDAs. The evidence identified persistent difficulties in capturing capacity gains, partnership quality, and systemic change, alongside limited mechanisms to track outcomes once initial funding ended.
                    <sup>
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref68">68</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref102">102</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> This misalignment reduced funders&#x2019; ability to demonstrate return on investment and limited the longer-term value of RDAs.</p>
                <p>In summary, the challenges associated with forming and sustaining equitable partnerships, particularly in interdisciplinary, intersectoral, and international contexts, are compounded by power imbalances, unclear roles, and insufficient time for building trust.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref35">35</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref68">68</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref70">70</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref103">103</xref>,
                        <xref ref-type="bibr" rid="ref114">114</xref>
                    </sup> These issues are further reinforced by cultural, administrative, and institutional barriers, including academic incentive structures that undervalue collaborative and co-productive work, limited infrastructure in some settings, and inflexible funding and reporting requirements.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref26">26</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref103">103</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup> Collectively, these challenges highlight that the effectiveness of RDAs is not inherent to the mechanism itself but is highly dependent on thoughtful funding design, adequate resourcing, proportional administration, and evaluation approaches that reflect the intended purpose of research development funding.</p>
            </sec>
            <sec id="sec16">
                <title>Achieving the intended outcomes (RQ4 and RQ5)</title>
                <p>This last section examines the extent to which RDAs achieve the outcomes they are intended to deliver, focusing on both the types of outcomes RDAs are particularly well-suited to achieving (RQ4) and the degree to which these outcomes are realised in practice (RQ5). Given the exploratory, short-term, and relatively low-cost nature of RDAs, the evidence rarely framed success in terms of traditional end-point indicators alone, such as publications or immediate policy change. Instead, outcomes were more commonly described in relation to readiness, relationship building, capability development, and progression towards future research activity and funding.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref36">36</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref103">103</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref109">109</xref>,
                        <xref ref-type="bibr" rid="ref113">113</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref115">115</xref>
                    </sup> As such, the evidence reflects considerable variation in how success is defined, reported, and measured, emphasising the importance of aligning expectations of impact with the developmental purpose of RDAs within the wider research funding landscape. (see 
                    <xref ref-type="table" rid="T6">
Table 6</xref>)</p>
                <table-wrap id="T6" orientation="portrait" position="float">
                    <label>
Table 6. </label>
                    <caption>
                        <title>Key concepts and statements on achieving the intended outcomes.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th align="left" colspan="1" rowspan="1" valign="top">Key themes</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Statements</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">No. refs</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="7" valign="middle">
                                    <bold>Does the evidence suggest any specific outcomes that RDAs are particularly well-suited to achieving</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Capacity Building</bold>: Enhancing research skills, methods, and readiness through training, mentorship, and workplace-based learning, improving capacity to conduct equitable community-engaged research
                                    <sup>
                                        <xref ref-type="bibr" rid="ref9">9</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref22">22</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref27">27</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref46">46</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref56">56</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref62">62</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref67">67</xref>,
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref80">80</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref92">92</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">24</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Partnership Formation and Network-building
</bold>: Catalysing collaborations, building cross-sector and LMIC&#x2013;HIC partnerships, fostering trust and science-practitioner networks, strengthening community-academic partnerships, accelerating collaborative pipelines for funded calls
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref30">30</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref57">57</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>&#x2013;
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref81">81</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>,
                                        <xref ref-type="bibr" rid="ref101">101</xref>,
                                        <xref ref-type="bibr" rid="ref107">107</xref>,
                                        <xref ref-type="bibr" rid="ref111">111</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">22</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Leveraging and Attracting Follow-on Funding:</bold> Securing subsequent major awards/grants and additional awards/grants through initial seed or catalyst funding, systematic leveraging of additional funding from follow-on support
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref76">76</xref>,
                                        <xref ref-type="bibr" rid="ref82">82</xref>,
                                        <xref ref-type="bibr" rid="ref83">83</xref>,
                                        <xref ref-type="bibr" rid="ref85">85</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref108">108</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">11</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Proof-of-Concept and Early-stage Outputs:</bold> Generating preliminary data, translational outputs, and early demonstrators and tools to reduce the risk of future funding, improving connections between discovery and functional studies
                                    <sup>
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref53">53</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref83">83</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref90">90</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">10</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Equity, inclusion, and Power-sharing:</bold> Promoting equitable partnerships, diversity, and inclusion in research collaborations, dedicated seed funding to establish diverse, equitable partnerships and counter structural inequities in grant decision-making, guidance for equitable partnerships and participation
                                    <sup>
                                        <xref ref-type="bibr" rid="ref25">25</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref47">47</xref>,
                                        <xref ref-type="bibr" rid="ref55">55</xref>,
                                        <xref ref-type="bibr" rid="ref58">58</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref66">66</xref>,
                                        <xref ref-type="bibr" rid="ref68">68</xref>,
                                        <xref ref-type="bibr" rid="ref73">73</xref>,
                                        <xref ref-type="bibr" rid="ref94">94</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">11</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Institutional, Policy, and Practice Change:</bold> Driving organisational transformation, policy updates, and improved practices through short-term awards/grants and development awards, strengthening EDI/inclusion practice through meaningful pre-award public involvement including co-designing environmental solutions
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref41">41</xref>,
                                        <xref ref-type="bibr" rid="ref49">49</xref>,
                                        <xref ref-type="bibr" rid="ref52">52</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref100">100</xref>,
                                        <xref ref-type="bibr" rid="ref106">106</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">9</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Infrastructure and System Strengthening:</bold> Building community infrastructure and improving systems for continuity of care, system capacity and data use in decision-making, cross-sector working partnerships and collaborations
                                    <sup>
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref21">21</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>,
                                        <xref ref-type="bibr" rid="ref69">69</xref>,
                                        <xref ref-type="bibr" rid="ref74">74</xref>,
                                        <xref ref-type="bibr" rid="ref107">107</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">7</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="3" valign="middle">
                                    <bold>To what extent does the evidence suggest that RDAs achieve the outcomes they set out to</bold>
</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Achieved:</bold> Strong achievements when funding was coordinated and multi-level, including enhanced institutional readiness and partnerships and knowledge exchange were central to success; Building collaboration/networking; Research capacity and partnerships; Innovation outcomes through multi-level funding; Equity and inclusion in institutional culture resulting in improved representation within academic and research settings; Knowledge transfer and mentoring
                                    <sup>
                                        <xref ref-type="bibr" rid="ref20">20</xref>,
                                        <xref ref-type="bibr" rid="ref23">23</xref>,
                                        <xref ref-type="bibr" rid="ref24">24</xref>,
                                        <xref ref-type="bibr" rid="ref37">37</xref>,
                                        <xref ref-type="bibr" rid="ref38">38</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref48">48</xref>,
                                        <xref ref-type="bibr" rid="ref60">60</xref>,
                                        <xref ref-type="bibr" rid="ref62">62</xref>,
                                        <xref ref-type="bibr" rid="ref64">64</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">10</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Partially Achieved</bold>: Improved infrastructure and partnerships but limited sustainability especially for short-term awards/grants; Short-term catalyst grants enabled proof-of-concept but lacked long-term impact (many struggling to maintain impact without follow-on funding); Partially achieved awards/grants relied on securing additional grants to sustain activities; Challenges in scaling and maintaining collaborations
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref38">38</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref71">71</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref88">88</xref>,
                                        <xref ref-type="bibr" rid="ref97">97</xref>,
                                        <xref ref-type="bibr" rid="ref101">101</xref>,
                                        <xref ref-type="bibr" rid="ref105">105</xref>,
                                        <xref ref-type="bibr" rid="ref106">106</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">10</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">
                                    <bold>Limited Achievement:</bold> Challenges in scaling and sustaining impact, especially those that required additional resources to maintain momentum; Public seed funding underperformed for entrepreneurship and commercialisation; Some awards/grants that aimed to foster partnerships faced structural challenges, including the lack of robust metrics to assess outcomes, making it difficult to attribute success or justify follow-on funding; Structural gaps and lack of monitoring reduced effectiveness; Limited evidence of systemic change
                                    <sup>
                                        <xref ref-type="bibr" rid="ref8">8</xref>,
                                        <xref ref-type="bibr" rid="ref39">39</xref>,
                                        <xref ref-type="bibr" rid="ref40">40</xref>,
                                        <xref ref-type="bibr" rid="ref43">43</xref>,
                                        <xref ref-type="bibr" rid="ref79">79</xref>,
                                        <xref ref-type="bibr" rid="ref85">85</xref>,
                                        <xref ref-type="bibr" rid="ref86">86</xref>,
                                        <xref ref-type="bibr" rid="ref105">105</xref>,
                                        <xref ref-type="bibr" rid="ref106">106</xref>
                                    </sup>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="bottom">9</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>The evidence indicated that RDAs are particularly well suited to achieving early-stage, developmental, and relational outcomes, rather than immediate or standalone impact. From the literature, RDAs most consistently achieved outcomes related to research capacity building, partnership formation, and the generation of early outputs that enabled progression to subsequent stages of funding.
                    <sup>
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref35">35</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref81">81</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref85">85</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref90">90</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>
                    </sup> A substantial proportion of articles reported that RDAs successfully enhanced research capacity.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref22">22</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref56">56</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref68">68</xref>,
                        <xref ref-type="bibr" rid="ref71">71</xref>,
                        <xref ref-type="bibr" rid="ref74">74</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref82">82</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>
                    </sup> Outcomes included improved methodological skills, increased confidence and readiness to conduct research, strengthened leadership and project management capabilities, and greater institutional preparedness for future funding.
                    <sup>
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref32">32</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref63">63</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref70">70</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref78">78</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref91">91</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup> These benefits were often achieved through a combination of structured training, mentoring, and experiential learning embedded within funded activities.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref65">65</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref67">67</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref72">72</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref75">75</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref114">114</xref>,
                        <xref ref-type="bibr" rid="ref115">115</xref>
                    </sup> Capacity gains were particularly evident in interdisciplinary, community-engaged, and applied research settings, where RDAs supported teams to develop new ways of working, adopt participatory approaches, and navigate complex research environments.
                    <sup>
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>,
                        <xref ref-type="bibr" rid="ref58">58</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>,
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref114">114</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup>
                </p>
                <p>When considering the extent to which RDAs achieved their stated aims, the evidence showed considerable variation. A subset of awards was described as fully achieving intended outcomes, particularly where funding was coordinated across multiple levels, institutional support was strong, and collaboration and knowledge exchange were central to the award design.
                    <sup>
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>
                    </sup> A larger proportion of RDAs were reported as partially achieving their aims, typically delivering early outputs, strengthening partnerships, or improving infrastructure but struggling to sustain activity without follow-on funding.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref71">71</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref88">88</xref>,
                        <xref ref-type="bibr" rid="ref97">97</xref>,
                        <xref ref-type="bibr" rid="ref101">101</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup> A smaller body of evidence indicated limited achievement, especially in cases where awards aimed to deliver longer-term or system-level change without sufficient time, resources, or evaluation mechanisms.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref26">26</xref>,
                        <xref ref-type="bibr" rid="ref39">39</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref85">85</xref>,
                        <xref ref-type="bibr" rid="ref86">86</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup>
                </p>
                <p>
Overall, the evidence suggests that RDAs are particularly well-suited to achieving developmental and relational outcomes, especially those related to capacity building, partnership formation, and early-stage research outputs. The strongest and most consistently reported achievements were improvements in research skills, methodological readiness, and collaborative capability, alongside the establishment of new networks and partnerships that often extend beyond the life of the funding award.
                    <sup>
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref20">20</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref33">33</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref42">42</xref>,
                        <xref ref-type="bibr" rid="ref44">44</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref51">51</xref>,
                        <xref ref-type="bibr" rid="ref53">53</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref61">61</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref64">64</xref>,
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref73">73</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref95">95</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref102">102</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref104">104</xref>,
                        <xref ref-type="bibr" rid="ref111">111</xref>,
                        <xref ref-type="bibr" rid="ref113">113</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>
                    </sup> RDAs were also effective in generating proof-of-concept outputs and leveraging follow-on funding, enabling teams to progress early ideas into larger, more substantive research projects. However, the extent to which RDAs achieved their intended outcomes varied considerably. While many awards were reported as achieving or partially achieving their aims, sustained impact was frequently contingent on additional funding, supportive institutional contexts, and aligned evaluation frameworks.
                    <sup>
                        <xref ref-type="bibr" rid="ref7">7</xref>,
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref29">29</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref37">37</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref45">45</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref55">55</xref>,
                        <xref ref-type="bibr" rid="ref57">57</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref66">66</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref69">69</xref>,
                        <xref ref-type="bibr" rid="ref72">72</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref76">76</xref>,
                        <xref ref-type="bibr" rid="ref79">79</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref84">84</xref>,
                        <xref ref-type="bibr" rid="ref91">91</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref101">101</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref107">107</xref>,
                        <xref ref-type="bibr" rid="ref116">116</xref>,
                        <xref ref-type="bibr" rid="ref117">117</xref>
                    </sup> Outcomes related to systemic change, long-term sustainability, and scale were less consistently achieved, reflecting the short-term and exploratory nature of RDAs. Collectively, the evidence indicates that RDAs are more effective when success is understood in terms of enabling readiness, strengthening relationships, and creating pathways to future opportunity, rather than delivering immediate, standalone impact.</p>
            </sec>
            <sec id="sec17">
                <title>Evidence from research funding and professional organisations</title>
                <p>To complement the scoping review findings, we examined publicly available information from a purposive sample of research funding and professional organisations. This review aimed to understand how RDAs, or conceptually similar mechanisms, are articulated, framed, and operationalised by funders, and to assess the extent to which these external descriptions align with the evidence identified in the academic and grey literature.</p>
                <p>In total, websites from 36 research funding and professional organisations were screened, including national and international research councils, charities, innovation agencies, and professional or regulatory bodies. Of these, 20 organisations met the inclusion criteria (refer to extended data 
                    <bold>S6 Table: Funders and professional organisations</bold>). It should be noted that, due to the current international funding environment, some webpages identified through the manual searches displayed notifications indicating that the content may not be up to date because of temporary lapses in government funding, or that funding pages have been closed or archived. Organisations were included where there was clear evidence of short-term, early-stage funding mechanisms focused on research development, capacity building, collaboration, innovation, or application development, rather than individual career or fellowship-based awards. The organisations represented a broad geographical distribution, including the UK, Europe, North America, Australasia, and Asia, and spanned health, biomedical research, innovation, technology, and interdisciplinary research domains.</p>
                <p>Across the included organisations, RDAs were described using a wide range of terminology, including seed funding, exploratory or development grants, capacity-building initiatives, networking or collaboration grants, application development awards, and early-concept funding. Consistent with findings from the scoping review, there was substantial variation in how these awards were defined, structured, and positioned within wider funding portfolios. The same terminology, such as &#x2018;development awards&#x2019; or &#x2018;capacity building&#x2019;, were interpreted differently across organisations and countries, often referring to distinctly different funding purposes. In several cases, development awards identified through keyword searches were found exclusively on career development or training, highlighting the challenges of terminology inconsistency used across research funding systems.</p>
                <p>Despite this variation, common features emerged across funder descriptions. Most funding /professional organisations emphasised the role of RDAs in strengthening institutional or collaborative research capacity, supporting early-stage or exploratory work, and enabling partnerships that could progress to larger, longer-term funding. For example, major national funders such as the National Institute of Health (NIH), US National Science Foundation (NSF), UK Research and Innovation (UKRI), and Wellcome positioned their exploratory, seed, or impact acceleration schemes as mechanisms to reduce the risk of innovation, test novel ideas, and bridge gaps between discovery and larger investment.
                    <sup>
                        <xref ref-type="bibr" rid="ref2">2</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref6">6</xref>
                    </sup> Similarly, European funding/professional organisations including Horizon Europe, the European Innovation Council (EIC), European Cooperation in Science and Technology (COST), and Interreg Europe highlighted networking, coordination, and capacity-building functions, often focusing on cross-border and interdisciplinary collaboration rather than individual researcher progression.</p>
                <p>A strong emphasis on collaboration and partnership development was evident across many organisations, particularly in international and global health funding contexts. Funders such as European and Developing Countries Clinical Trials Partnership (EDCTP), Grand Challenges Canada, and regional development initiatives, framed RDAs as tools to foster equitable partnerships, support multi-county consortia, and strengthen research ecosystems in resource-constrained settings.
                    <sup>
                        <xref ref-type="bibr" rid="ref1">1</xref>,
                        <xref ref-type="bibr" rid="ref119">119</xref>
                    </sup> These descriptions closely aligned with the review evidence highlighting RDAs&#x2019; roles in enabling relationship-building, shared agenda-setting, and institutional readiness for future funding.</p>
                <p>However, the review of funding/professional organisations also reinforced the gaps identified in the literature. While many organisations clearly articulated the intent of RDAs, to build capacity, stimulate collaboration, and catalyse innovation, there was limited publicly available information evidencing outcomes, effectiveness, or longer-term impact of these awards. Few funder webpages reported formal evaluations, success metrics beyond follow-on funding, or systematic assessments of partnership quality, equity, or sustainability. In cases where impact was mentioned, it was often implied rather than demonstrated, with success inferred through progression to larger grants or alignment with strategic priorities.</p>
                <p>Overall, the evidence from funding and professional organisations corroborates the scoping review findings, demonstrating that RDAs are widely used and strategically valued across diverse funding systems, but remain inconsistently defined and inadequately evidenced in terms of outcomes and impact. The lack of transparent evaluation and reporting mechanisms limits cross-funder learning and constrains the ability to develop evidence-informed best practice for RDA design and implementation. These findings reinforce the need for greater clarity in terminology, improved alignment between intended and measured outcomes, and more systematic approaches to monitoring and evaluating research development funding within the wider research funding landscape.</p>
            </sec>
            <sec id="sec18">
                <title>Perspective of funders and funded research teams</title>
                <p>RDAs occupy a distinct position within research funding portfolios, operating as flexible, early-stage mechanisms intended to enable capacity building, partnership development, and innovation across diverse research settings. The evidence drawn from both the scoping review and the funding and professional organisations demonstrates that RDAs are commonly used to support exploratory activity, relationship-building, feasibility, and preparedness for larger-scale funding, rather than to deliver standalone or fully realised outcomes. As such, RDAs are best understood as part of a broader research funding opportunities in which their value lies in enabling progression, learning, and system-level development. The following section examines how the evidence describes the approaches used by both funders and funded research teams to shape, adapt, and support RDAs in practice, particularly in response to the structural and implementation issues identified across the literature.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Funder perspective (Research Funding Organisations (RFOs))</italic>
</bold>
                </p>
                <p>From the funder perspective (55 articles), the evidence highlights a growing recognition that RDAs require deliberate design features to mitigate well-documented challenges related to short duration, sustainability, and evaluation. Key funder-led initiatives emphasised the importance of staged and flexible funding models, often incorporating inception or catalyst phases that focus explicitly on partnership development, co-design, and readiness rather than predefined deliverables. For example, programmes such as Research for Evidence into Action for Clean Water (REACH),
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>
                    </sup> German Alliance for Global Health Research (GLOHRA),
                    <sup>
                        <xref ref-type="bibr" rid="ref62">62</xref>
                    </sup> and structured seed grant schemes described by Bailey 
                    <italic toggle="yes">et al</italic>. and Charles 
                    <italic toggle="yes">et al.</italic> illustrate how funders have sought to incorporate learning periods, iterative progression, and opportunities for follow-on support to address the limitations of single, short-term awards.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>
                    </sup>
                </p>
                <p>Funders also increasingly acknowledged the limitations of traditional evaluation metrics when applied to RDAs.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref26">26</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>
                    </sup> Several key papers highlighted efforts to move beyond outputs such as publications or immediate policy change, instead adopting process-focused and relational indicators to capture capacity building, partnership quality, and enabling environments.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>
                    </sup> This included the use of advisory boards, qualitative reporting, milestone-based progression, and reflective evaluations designed to evidence incremental or foundational change. Nonetheless, the evidence indicates that such approaches remain unevenly applied, and many funders continue to struggle with demonstrating return on investment for RDAs whose value emerges over longer-time horizons.</p>
                <p>Equity and partnership challenges were also addressed explicitly in the funder literature. Many funders articulated a commitment to equitable collaboration and sought to operationalise this through the design of RDA schemes, particularly in community-engaged, global health, and interdisciplinary research. These efforts included mechanisms such as joint governance arrangements, shared decision-making, mentoring, and technical assistance. However, the evidence suggests that these measures often coexist with structural constraints, such as inflexible contracting arrangements, administrative burdens, or unequal control over resources, that continue to undermine equitable intent.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup> As a result, several funder analyses highlighted the need for clearer guidance, longer funding horizons, and enhanced alignment between funding rules and partnership principles.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup>
                </p>
                <p>

                    <bold>

                        <italic toggle="yes">Funded perspective (Funded organisations or research teams)</italic>
</bold>
                </p>
                <p>From the funded perspective (42 articles), RDAs were widely viewed as valuable but inherently insufficient as stand-alone interventions, with many challenges arising after the award period ended.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref9">9</xref>,
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>,
                        <xref ref-type="bibr" rid="ref78">78</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup> Case studies such as Colchamiro 
                    <italic toggle="yes">et al.</italic> and Coombe 
                    <italic toggle="yes">et al.</italic> illustrated how short timelines constrained staffing, engagement, and evaluation, often requiring no-cost extensions or ad hoc resource mobilisation to complete intended activities.
                    <sup>
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>
                    </sup>
                </p>
                <p>Funded researchers and partners also highlighted challenges related to administrative and temporal misalignment, including tight spending deadlines, inflexible reporting requirements, and limited support for non-traditional activities such as community engagement or co-production. In several studies, practitioners and community partners described the disproportionate burden placed on them by short-term awards, particularly where compensation, training, or infrastructure support was insufficient.
                    <sup>
                        <xref ref-type="bibr" rid="ref8">8</xref>,
                        <xref ref-type="bibr" rid="ref24">24</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref78">78</xref>,
                        <xref ref-type="bibr" rid="ref100">100</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup> These constraints were seen as contributing to partnership fatigue and inequity, despite the developmental aims of RDAs.</p>
                <p>Evaluation challenges were particularly salient in the funded perspective. Many teams reported difficulty evidencing success when outcomes were relational, or longer-term, and where evaluation frameworks did not reflect the purpose of the award.
                    <sup>
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref25">25</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref105">105</xref>
                    </sup> In response, some funded research teams developed alternative approaches to evidencing impact, including process mapping, collaboration metrics, narrative accounts, and tracking of subsequent funding or institutional change. However, the extraction shows that such approaches were often locally developed and rarely embedded systematically across funding schemes.
                    <sup>
                        <xref ref-type="bibr" rid="ref26">26</xref>,
                        <xref ref-type="bibr" rid="ref40">40</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref60">60</xref>,
                        <xref ref-type="bibr" rid="ref62">62</xref>,
                        <xref ref-type="bibr" rid="ref80">80</xref>,
                        <xref ref-type="bibr" rid="ref94">94</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>
                    </sup>
                </p>
                <p>

                    <bold>

                        <italic toggle="yes">Convergence and divergence across perspectives</italic>
</bold>
                </p>
                <p>The extracted evidence suggests a strong convergence between funder and funded perspectives in how the role and value of RDAs are understood, even if their implementation varies in practice. Across both perspectives, RDAs are consistently positioned as enabling mechanisms that prioritise time, flexibility, relational work, and learning, rather than as instruments for delivering immediate or standalone research outputs. Both funders and funded teams recognised that RDAs function most effectively when situated within a wide funding ecosystem, supporting readiness, partnership formation, and progression to subsequent stages of research rather than operating as isolated interventions.</p>
                <p>Where perspectives differed between funders and funded research teams was less in their intent and more in the operational processes and lived experience. Funders frequently articulated ambitions related to sustainability, equity, and longer-term impact, while funded research teams emphasised how these ambitions were mediated by funding design features such as award duration, evaluation expectations, and institutional constraints. Evidence from both sides suggested that misalignments between stated objectives and funding rules or reporting frameworks could limit the extent to which RDAs realised their full potential. Conversely, alignment between funding design, evaluation, and expectations, that are achieved for example, through staged or phased funding, embedded capacity-building support, and proportionate governance, was associated with fewer reported challenges related to sustainability, partnership quality, and uncertainty about outcomes across both funder and funded accounts.
                    <sup>
                        <xref ref-type="bibr" rid="ref21">21</xref>,
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref47">47</xref>,
                        <xref ref-type="bibr" rid="ref77">77</xref>,
                        <xref ref-type="bibr" rid="ref99">99</xref>
                    </sup>
                </p>
                <p>Importantly, the evidence demonstrates that RDAs were widely valued not only for what they produced, but for what they enabled. Success was frequently framed in terms of strengthened relationships, enhanced confidence and capability, institutional learning, and the creation of credible pathways to future funding, policy engagement, or practice change.
                    <sup>
                        <xref ref-type="bibr" rid="ref23">23</xref>,
                        <xref ref-type="bibr" rid="ref27">27</xref>,
                        <xref ref-type="bibr" rid="ref28">28</xref>,
                        <xref ref-type="bibr" rid="ref31">31</xref>,
                        <xref ref-type="bibr" rid="ref38">38</xref>,
                        <xref ref-type="bibr" rid="ref41">41</xref>,
                        <xref ref-type="bibr" rid="ref43">43</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref46">46</xref>,
                        <xref ref-type="bibr" rid="ref48">48</xref>,
                        <xref ref-type="bibr" rid="ref50">50</xref>,
                        <xref ref-type="bibr" rid="ref52">52</xref>,
                        <xref ref-type="bibr" rid="ref54">54</xref>,
                        <xref ref-type="bibr" rid="ref59">59</xref>,
                        <xref ref-type="bibr" rid="ref83">83</xref>,
                        <xref ref-type="bibr" rid="ref87">87</xref>,
                        <xref ref-type="bibr" rid="ref89">89</xref>,
                        <xref ref-type="bibr" rid="ref92">92</xref>,
                        <xref ref-type="bibr" rid="ref93">93</xref>,
                        <xref ref-type="bibr" rid="ref95">95</xref>,
                        <xref ref-type="bibr" rid="ref96">96</xref>,
                        <xref ref-type="bibr" rid="ref106">106</xref>&#x2013;
                        <xref ref-type="bibr" rid="ref108">108</xref>,
                        <xref ref-type="bibr" rid="ref113">113</xref>,
                        <xref ref-type="bibr" rid="ref115">115</xref>
                    </sup> This shared understanding challenges narrow conceptions of impact based solely on publications or short-term deliverables and instead highlights the importance of recognising developmental value, readiness, and pathway creation as legitimate and necessary outcomes of research development funding.</p>
                <p>Overall, the synthesis suggests that maximising the effectiveness of RDAs depends less on resolving isolated challenges and more on embedding a coherent set of principles across funder strategies and funded practice. These include valuing relational and developmental work, acknowledging the temporal nature of capacity building and collaboration, and adopting evaluation approaches that reflect the intended purpose of RDAs. When these principles are consistently applied, RDAs are positioned not as marginal or preparatory add-ons, but as a strategically important component of the research funding landscape, capable of strengthening research systems, partnerships, and future impact.</p>
            </sec>
        </sec>
        <sec id="sec19" sec-type="discussion">
            <title>Discussion</title>
            <p>This scoping review demonstrates that RDAs occupy a distinctive and increasingly strategic position within contemporary research funding landscapes. Across both funder and funded perspectives, RDAs are consistently understood not as mechanisms for delivering immediate or standalone research outputs, but as developmental infrastructure that enables collaboration, capacity building, and progression within broader funding ecosystems. This shared framing marks an important shift away from viewing RDAs as marginal or preparatory add-ons, towards recognising their role in shaping research readiness, partnership quality, and longer-term impact pathways.</p>
            <p>This scoping review offers the first cross-disciplinary synthesis of RDAs, spanning health, global development, innovation, environmental sustainability, and applied research contexts. By also bringing together funder and funded perspectives across diverse settings, the review moves beyond scheme-specific evaluations to identify shared principles, recurring tensions, and system-level implications for the design and use of RDAs. A central contribution of this synthesis is the identification of strong conceptual convergence between funders and funded research teams regarding the purpose and value of RDAs, even where operational experiences diverge in practice. Across both perspectives, time, flexibility, and relational work were consistently emphasised as core conditions for effectiveness, and RDAs were widely understood to function best when embedded within multi-stage funding pathways.
                <sup>
                    <xref ref-type="bibr" rid="ref20">20</xref>,
                    <xref ref-type="bibr" rid="ref23">23</xref>,
                    <xref ref-type="bibr" rid="ref27">27</xref>,
                    <xref ref-type="bibr" rid="ref31">31</xref>,
                    <xref ref-type="bibr" rid="ref41">41</xref>,
                    <xref ref-type="bibr" rid="ref45">45</xref>,
                    <xref ref-type="bibr" rid="ref46">46</xref>,
                    <xref ref-type="bibr" rid="ref50">50</xref>,
                    <xref ref-type="bibr" rid="ref56">56</xref>,
                    <xref ref-type="bibr" rid="ref62">62</xref>,
                    <xref ref-type="bibr" rid="ref69">69</xref>,
                    <xref ref-type="bibr" rid="ref70">70</xref>,
                    <xref ref-type="bibr" rid="ref73">73</xref>,
                    <xref ref-type="bibr" rid="ref83">83</xref>,
                    <xref ref-type="bibr" rid="ref95">95</xref>,
                    <xref ref-type="bibr" rid="ref96">96</xref>,
                    <xref ref-type="bibr" rid="ref109">109</xref>
                </sup> Therefore, RDAs are less about scale and more about sequencing, reducing innovation risk, creating space for exploratory or co-productive work, and enabling teams to establish the trust, governance arrangements, and preliminary outputs required to progress toward sustained research investment.</p>
            <p>The review also highlights that convergence at the level of intent does not always translate into consistency in practice. Funders frequently articulated ambitions related to sustainability, equity, and longer-term impact, but funded research teams described how these ambitions were often constrained by award duration, evaluation expectations, and institutional structures.
                <sup>
                    <xref ref-type="bibr" rid="ref9">9</xref>,
                    <xref ref-type="bibr" rid="ref23">23</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref25">25</xref>,
                    <xref ref-type="bibr" rid="ref27">27</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref29">29</xref>,
                    <xref ref-type="bibr" rid="ref31">31</xref>,
                    <xref ref-type="bibr" rid="ref33">33</xref>,
                    <xref ref-type="bibr" rid="ref36">36</xref>,
                    <xref ref-type="bibr" rid="ref37">37</xref>,
                    <xref ref-type="bibr" rid="ref44">44</xref>,
                    <xref ref-type="bibr" rid="ref46">46</xref>,
                    <xref ref-type="bibr" rid="ref47">47</xref>,
                    <xref ref-type="bibr" rid="ref50">50</xref>,
                    <xref ref-type="bibr" rid="ref54">54</xref>,
                    <xref ref-type="bibr" rid="ref60">60</xref>,
                    <xref ref-type="bibr" rid="ref62">62</xref>,
                    <xref ref-type="bibr" rid="ref65">65</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref67">67</xref>,
                    <xref ref-type="bibr" rid="ref69">69</xref>,
                    <xref ref-type="bibr" rid="ref73">73</xref>,
                    <xref ref-type="bibr" rid="ref75">75</xref>,
                    <xref ref-type="bibr" rid="ref77">77</xref>,
                    <xref ref-type="bibr" rid="ref79">79</xref>,
                    <xref ref-type="bibr" rid="ref83">83</xref>,
                    <xref ref-type="bibr" rid="ref91">91</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref94">94</xref>,
                    <xref ref-type="bibr" rid="ref96">96</xref>,
                    <xref ref-type="bibr" rid="ref99">99</xref>,
                    <xref ref-type="bibr" rid="ref100">100</xref>,
                    <xref ref-type="bibr" rid="ref106">106</xref>,
                    <xref ref-type="bibr" rid="ref111">111</xref>,
                    <xref ref-type="bibr" rid="ref115">115</xref>,
                    <xref ref-type="bibr" rid="ref116">116</xref>
                </sup> Where RDAs were designed with staged funding, proportionate governance, and evaluation approaches that reflected developmental aims, challenges related to sustainability, partnership quality, and outcome uncertainty were less pronounced.
                <sup>
                    <xref ref-type="bibr" rid="ref21">21</xref>,
                    <xref ref-type="bibr" rid="ref27">27</xref>,
                    <xref ref-type="bibr" rid="ref28">28</xref>,
                    <xref ref-type="bibr" rid="ref40">40</xref>,
                    <xref ref-type="bibr" rid="ref41">41</xref>,
                    <xref ref-type="bibr" rid="ref53">53</xref>,
                    <xref ref-type="bibr" rid="ref55">55</xref>,
                    <xref ref-type="bibr" rid="ref56">56</xref>,
                    <xref ref-type="bibr" rid="ref73">73</xref>,
                    <xref ref-type="bibr" rid="ref79">79</xref>,
                    <xref ref-type="bibr" rid="ref89">89</xref>,
                    <xref ref-type="bibr" rid="ref94">94</xref>,
                    <xref ref-type="bibr" rid="ref96">96</xref>,
                    <xref ref-type="bibr" rid="ref97">97</xref>,
                    <xref ref-type="bibr" rid="ref100">100</xref>,
                    <xref ref-type="bibr" rid="ref104">104</xref>
                </sup> Conversely, where design and reporting frameworks remained anchored in short-term output metrics, RDAs struggled to realise their full potential despite strong underlying intent.</p>
            <p>These findings reinforce the importance of understanding RDAs as process-oriented investments rather than outcome-driven interventions. Across disciplines and contexts, success was more often described in terms of what RDAs enabled, such as new relationships, enhanced confidence and capability, institutional learning, and credible pathways to future funding or practice change, rather than in relation to publications or immediate policy influence. This aligns with wider critiques of dominant research evaluation paradigms and underscores the limitations of narrow, output-centric conceptions of success when applied to development-stage funding.
                <sup>
                    <xref ref-type="bibr" rid="ref120">120</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref122">122</xref>
                </sup> For RDAs, value frequently lies in relational and temporal dimensions that unfold beyond the life of the award and resist simple quantification, consistent with work on developmental evaluation and systems-oriented approaches to assessing research and innovation.
                <sup>
                    <xref ref-type="bibr" rid="ref123">123</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref125">125</xref>
                </sup>
            </p>
            <p>Importantly, the review also demonstrates that the effectiveness of RDAs is highly contingent on contextual and systemic factors. RDAs were particularly valued in resource-constrained, interdisciplinary, community-engaged, and time-sensitive settings, where flexible funding and protected time enabled work that would otherwise remain unfunded. However, these same contexts often exposed structural vulnerabilities, including reliance on short-term awards to support labour-intensive relational work, limited institutional backing for partnership structures, and weak mechanisms for sustaining activity once initial funding ended. These dynamics suggest that RDAs cannot, and should not, be expected to compensate for deficiencies elsewhere in the funding system.</p>
            <p>Taken together, the evidence indicates that maximising the contribution of RDAs requires moving beyond treating them as isolated instruments and instead embedding them within coherent funding strategies that recognise developmental value, readiness, and pathway creation as legitimate outcomes. Rather than asking whether RDAs &#x201c;work&#x201d; in isolation, a more productive framing is how RDAs interact with other funding mechanisms, institutional supports, and evaluation systems to strengthen the research ecosystems over time. From this perspective, RDAs emerge not as small grants with limited horizons, but as strategically important tools whose impact depends on alignment, sequencing, and sustained recognition of the relational labour that underpins effective research.</p>
            <sec id="sec20">
                <title>Strengths and limitations</title>
                <p>This scoping review was designed to address fragmented and under-synthesised evidence on RDAs, rather than to evaluate the effectiveness of individual funding schemes. As such, its primary strength lies in the breadth and integrative nature of the synthesis, bringing together evidence across disciplines, sectors, and international contexts, and incorporating both funder and funded perspectives. To our knowledge, this is the first scoping review to examine RDAs in this cross-cutting way, moving beyond scheme-specific or discipline-bound analyses to identify shared principles, recurring challenges, and system-level implications for research funding practice.</p>
                <p>A further strength is the inclusion of grey literature and publicly available funder documentation, which was essential given the limited number of formal evaluations of RDAs. Many insights into award purpose, design, and perceived value were not captured in academic journals but were articulated through reports, discussion documents, and reflective accounts produced by funders and research organisations. Including these sources enabled a richer understanding of how RDAs are conceptualised and operationalised in practice, particularly in relation to capacity building, partnership development, and research readiness.</p>
                <p>The review also benefits from an explicit focus on context and purpose, rather than assuming RDAs represent a uniform intervention. By iteratively refining definitions and inclusion criteria during the review process, the synthesis reflects the diversity of mechanisms labelled as seed funding, catalyst awards, development grants, or application development funding. This approach strengthens the relevance of the findings for RFOs operating across different systems, whilst acknowledging that RDAs are inherently heterogeneous by design.</p>
                <p>However, several limitations should be considered when interpreting the findings. First, as a scoping review, no formal appraisal of study quality was undertaken, in line with established methodological guidance.
                    <sup>
                        <xref ref-type="bibr" rid="ref14">14</xref>
                    </sup> The included articles varied widely in design and depth, and many relied on descriptive or reflective reporting rather than robust evaluation. This reflects the nature of the field rather than a shortcoming of the review, but it limits the extent to which causal claims about effectiveness can be made.</p>
                <p>Second, the evidence base was unevenly distributed across disciplines and geographies, with a predominance of literature from health, global health, and Anglophone contexts. While RDAs are widely used across research systems, their reporting is influenced by disciplinary norms and publication practices, which may have shaped the visibility of certain perspectives. Similarly, funder-authored and evaluator-led publications were more common than independent empirical studies, potentially introducing a degree of reporting bias.</p>
                <p>Third, the review was conducted during a period of unusual volatility in the international research funding environment, which affected the availability and completeness of publicly accessible information. During the manual searches of research funding and professional organisation websites, a small number of webpages displayed notifications indicating that content may not be up to date due to temporary lapses in government funding, organisational restructuring, or programme closures. In some cases, programme pages had been archived or removed, limiting access to detailed descriptions of research development or capacity-building awards. As a result, publicly available information for a small subset of funding schemes was partial or incomplete at the time of review, which may have constrained the visibility of recent funding developments in those cases.</p>
                <p>Finally, despite the inclusion of funded perspectives, the review is constrained by the way in which RDA outcomes and experiences are reported in the literature. Many relational, developmental, and longer-term effects of RDAs are diffuse, emergent, and difficult to evidence, and are therefore under-represented in published accounts. As a result, the review is more informative about intended value, perceived benefit, and system-level alignment than about longer-term outcomes or comparative impact.</p>
                <p>Taken together, these limitations reinforce rather than undermine the core findings of the review. They highlight that RDAs are widely valued and strategically important but remain weakly evidenced within conventional evaluative frameworks, underscoring the need for more proportionate, context-sensitive approaches to evaluation and reporting that reflect the developmental purpose of research development funding within wider research ecosystems.</p>
            </sec>
            <sec id="sec21">
                <title>Future considerations</title>
                <p>The findings of this scoping review point to several important considerations for the future design, implementation, and study of RDAs. While RDAs are widely valued as flexible and enabling mechanisms, their increasing use across disciplines and funding systems highlights the need for greater conceptual clarity, more proportionate evaluation approaches, and improved alignment between intention and practice.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Clarifying the role of RDAs within funding ecosystems</italic>
</bold>
                </p>
                <p>A recurring theme across the evidence was that RDAs can be most effective when understood as components of wider funding ecosystems rather than as discrete, stand-alone awards. Future funding strategies may benefit from more explicit positioning of RDAs within multi-stage or sequenced funding pathways, clarifying how they connect to subsequent opportunities and what forms of progression or readiness they are intended to support. Greater transparency around the role of RDAs in funding portfolios, including their relationship to larger grants, fellowships, or implementation funding, could help manage expectations for both funders and funded teams and reduce tensions around sustainability and outcome attribution.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Developing evaluation approaches that reflect developmental purpose</italic>
</bold>
                </p>
                <p>The review highlights persistent misalignment between the developmental aims of RDAs and the evaluation frameworks used to assess them. Future work is needed to develop evaluation approaches that are commensurate with the purpose, scale, and timeframe of RDAs, particularly where awards focus on capacity building, partnership development, or exploratory work. Rather than relying solely on output-based metrics or follow-on funding as proxies for success, funders may wish to explore structured yet flexible approaches that capture relational, process-based, and readiness outcomes, while remaining proportionate to the size of the award. Embedding learning-oriented evaluation at funding level, rather than relying on ad hoc or locally developed approaches, may also support cross-scheme learning and more consistent evidence generation.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Strengthening evidence on longer-term and system-level effects</italic>
</bold>
                </p>
                <p>A key gap identified by this review concerns the longer-term and system-level effects of RDAs, including their contribution to sustained collaboration, institutional change, and research culture. Much of the existing literature focuses on immediate or short-term outcomes, reflecting both the nature of RDAs and the limitations of current reporting practices. Future research could use longitudinal or funding-level designs to explore how RDAs contribute to longer trajectories of research development, particularly in relation to equity, inclusion, and capacity strengthening in under-resourced settings. Such work would be particularly valuable in understanding the cumulative effects of repeated or coordinated RDA investments over time.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Addressing structural and contextual constraints</italic>
</bold>
                </p>
                <p>The evidence also suggests that the effectiveness of RDAs is shaped by broader structural and contextual factors, including institutional incentive systems, administrative requirements, and volatility in the research funding landscape. Future considerations for funders and policymakers include how RDAs can be better supported through aligned contracting arrangements, realistic timelines, and adequate resourcing for relational work, particularly in community-engaged, interdisciplinary, and international research. Attention to these contextual enablers may be as important as adjustments to award size or duration in determining the value derived from RDA investments.</p>
                <p>

                    <bold>

                        <italic toggle="yes">Advancing conceptual coherence and shared language</italic>
</bold>
                </p>
                <p>Finally, the wide variation in terminology and descriptors used to describe RDAs presents challenges for synthesis, comparison, and learning across research funding systems. Future work could usefully focus on developing shared conceptual frameworks or typologies that distinguish between different types of research development funding based on purpose, context, and intended outcomes, rather than the award alone. Greater conceptual coherence would support more meaningful comparison across funding and enable RFOs to draw more effectively on the growing, but still fragmented, body of literature in this area.</p>
            </sec>
        </sec>
        <sec id="sec22" sec-type="conclusions">
            <title>Conclusions</title>
            <p>This scoping review provides the first cross-disciplinary synthesis of evidence on RDAs. By integrating both funder and funded perspectives, and drawing on academic and grey literature, the review offers a comprehensive picture of how RDAs are conceptualised, implemented, and valued across diverse research funding systems.</p>
            <p>The evidence demonstrates strong convergence across perspectives in how RDAs are understood as flexible, early-stage mechanisms designed to enable collaboration, build capacity, and support readiness for larger-scale research investment. RDAs were consistently positioned as most valuable when they create space for relational work, exploratory activity, and learning, rather than when they are judged against narrow, output-centric expectations. In this respect, RDAs function most effectively not as isolated grants, but as enabling components within wider funding ecosystems, supporting progression, sequencing, and reducing the risk of innovation.</p>
            <p>At the same time, the review highlights persistent divergence between intent and practice. While funders increasingly articulate ambitions related to sustainability, equity, and long-term impact, funded teams frequently experience constraints linked to short award durations, misaligned evaluation frameworks, administrative burden, and limited institutional backing. These issues do not reflect fundamental flaws in RDAs as a mechanism, but rather the consequences of insufficient alignment between funding design, governance, evaluation, and the developmental purpose of these types of awards.</p>
            <p>A central finding of the review was that the value of RDAs often lies in outcomes that are relational, contextual, and temporal, including strengthened partnerships, enhanced confidence and capability, institutional learning, and the creation of pathways to future funding or practice change. Such outcomes frequently unfold beyond the life of the award and resist straightforward quantification, explaining why RDAs remain weakly evidenced within conventional evaluation paradigms. This underscores the need to move beyond narrow conceptions of success and to adopt proportionate, purpose-aligned approaches to evaluating research development funding.</p>
            <p>Overall, the review suggests that the effectiveness of RDAs depends less on the size or duration of individual awards and more on how coherently they are embedded within funding strategies. RDAs realise their greatest potential when they are clearly positioned within multi-stage funding pathways, supported by flexible and equitable governance arrangements, and evaluated using frameworks that reflect their developmental role. When these conditions are met, RDAs emerge not as marginal or preparatory instruments, but as strategically important investments capable of strengthening research ecosystems, enabling inclusive collaboration, and supporting more sustainable pathways to research impact.</p>
            <p>By articulating shared principles, identifying key tensions, and highlighting gaps in the current literature, this review provides a foundation for more transparent, evidence-informed use of RDAs. It offers funders, policymakers, and research communities a clearer basis for designing, supporting, and evaluating RDAs in ways that maximise their contribution to robust, equitable, and impactful research systems.</p>
        </sec>
        <sec id="sec23">
            <title>Supporting information</title>
            <p>S1 Appendix Search terms and keywords</p>
            <p>S2 Appendix PRISMA ScR checklist</p>
            <p>S1 Table Descriptors for field and setting</p>
            <p>S2 Table Search strategies</p>
            <p>S3 Table Full details of included articles</p>
            <p>S4 Table Funders and professional organisations</p>
        </sec>
        <sec id="sec24">
            <title>Registration</title>
            <p>This study is registered with the RoR Registry (study number 4720) and can be accessed here: 
                <ext-link ext-link-type="uri" xlink:href="https://ror-hub.org/study/4720/">https://ror-hub.org/study/4720/</ext-link>
            </p>
        </sec>
        <sec id="sec25">
            <title>Ethics and Consent</title>
            <p>Ethical approval was not required as no participant information or data were used for the scoping review.</p>
        </sec>
    </body>
    <back>
        <sec id="sec28" sec-type="data-availability">
            <title>Data availability statement</title>
            <p>No data are associated with this article. All materials related to the scoping review are located at: 
                <ext-link ext-link-type="uri" xlink:href="https://osf.io/jthq5/overview">https://osf.io/jthq5/overview</ext-link> (DOI: 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.17605/OSF.IO/JTHQ5">https://doi.org/10.17605/OSF.IO/JTHQ5</ext-link>)
                <sup>
                    <xref ref-type="bibr" rid="ref126">126</xref>
                </sup>
            </p>
            <p>

                <bold>License</bold>: CC-By Attribution 4.0 International</p>
            <sec id="sec29">
                <title>Extended data</title>
                <p>

                    <bold>OSF</bold>: A scoping review on the use of Research Development Awards by research funding organisations in the UK and beyond - 
                    <ext-link ext-link-type="uri" xlink:href="https://osf.io/jthq5/overview">https://osf.io/jthq5/overview</ext-link> (DOI: 
                    <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.17605/OSF.IO/JTHQ5">https://doi.org/10.17605/OSF.IO/JTHQ5</ext-link>)
                    <sup>
                        <xref ref-type="bibr" rid="ref126">126</xref>
                    </sup>
                </p>
                <p>

                    <bold>License</bold>: CC-By Attribution 4.0 International</p>
                <p>The project contains the following extended data:</p>
                <p>
Figure 1 PRISMA flow diagram</p>
                <p>
Figure 2 Themed areas</p>
                <p>S1 Appendix Search terms and keywords</p>
                <p>S2 Appendix PRISMA ScR checklist</p>
                <p>S1 Table Descriptors for field and setting</p>
                <p>S2 Table Search strategies</p>
                <p>S3 Table Full details of included articles</p>
                <p>S4 Table Funders and professional organisations</p>
            </sec>
        </sec>
        <ack>
            <title>Acknowledgements</title>
            <p>We would like to thank the University of Southampton, Library Services, Engagement Group, in particular Max Cai, for their support in developing the search strategies for the review, and the NIHR Coordinating Centre staff for their support during the development of the scoping review. Microsoft Copilot (GPT-based language model) was used to complement the grey literature searching for funding organisations and verify the data extraction process. All data analyses, interpretations, and final decisions were conducted by the authors (AJBJ, BG,HC) who take full responsibility for the accuracy and integrity of the review findings. This research was conducted through the Insight and Evaluation team in the NIHR Coordinating Centre. The views and opinions expressed in the Discussion are those of the authors and do not necessarily reflect those of the Department of Health and Social Care.</p>
        </ack>
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