<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="other" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">F1000Research</journal-id>
            <journal-title-group>
                <journal-title>F1000Research</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2046-1402</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/f1000research.17693.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Note</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Massive open online courses on biomedical informatics</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 2 not approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Quispe-Juli</surname>
                        <given-names>Cender Udai</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-0633-8339</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Moquillaza-Alc&#x00e1;ntara</surname>
                        <given-names>Victor Hugo</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-0362-907X</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Arapa-Apaza</surname>
                        <given-names>Katherine</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-8640-2515</uri>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Biomedical Informatics in Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:cender.quispe@upch.pe">cender.quispe@upch.pe</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>14</day>
                <month>2</month>
                <year>2019</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2019</year>
            </pub-date>
            <volume>8</volume>
            <elocation-id>180</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>1</day>
                    <month>2</month>
                    <year>2019</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2019 Quispe-Juli CU et al.</copyright-statement>
                <copyright-year>2019</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://f1000research.com/articles/8-180/pdf"/>
            <abstract>
                <p>This study aimed to identify the characteristics of massive open online courses (MOOCs) related to biomedical informatics offered in several plataforms. We conducted an observational study on specialized MOOCs platforms to find courses related to biomedical informatics, in 2018. Our search identified 67 MOOCs on biomedical informatics. The majority of MOOCs were offered by Coursera (71.6%, 48/67), English was the most common language (95.5%, 64/67). The United States developed the majority of courses (73.1%, 49/67), with the vast majority of MOOCs being offered by universities (94%, 63/67). The majority of MOOCs were in bioinformatics (56.7%, 38/67) and data science (47.7%, 32/67). In conclusion, the MOOCs on biomedical informatics were focused in bioinformatics and data science, and were offered in English by institutions in the developing world.</p>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>computer-assisted instruction</kwd>
                <kwd>medical informatics</kwd>
                <kwd>bioinformatics</kwd>
                <kwd>education</kwd>
                <kwd>continuing education</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1" xlink:href="http://dx.doi.org/10.13039/501100002850">
                    <funding-source>Fondo Nacional de Desarrollo Cient&#x00ed;fico y Tecnol&#x00f3;gico</funding-source>
                </award-group>
                <funding-statement>This research was funded with a contribution of Peruvian National Science and Technology Fund (FONDECYT).</funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec sec-type="intro">
            <title>Introduction</title>
            <p>Biomedical informatics (BI) is &#x201c;the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated by efforts to improve human health&#x201d;
                <sup>
                    <xref ref-type="bibr" rid="ref-1">1</xref>
                </sup>. BI has an important role in healthcare therefore health professionals well-trained in the use of information and communication technology are needed
                <sup>
                    <xref ref-type="bibr" rid="ref-2">2</xref>
                </sup>.</p>
            <p>In developing countries, a few of they have developed training programmes in biomedical or health informatics
                <sup>
                    <xref ref-type="bibr" rid="ref-3">3</xref>
                </sup>. These programmes are short courses, Master&#x2019;s programmes and even sub-specialty programmes
                <sup>
                    <xref ref-type="bibr" rid="ref-3">3</xref>
                </sup>. However, these do not supply the need for health professionals with BI skills. The internet allows health professionals to have easy access to educative sources through platforms such massive open online courses (MOOCs)
                <sup>
                    <xref ref-type="bibr" rid="ref-4">4</xref>
                </sup>.</p>
            <p>MOOCs are accessible through the web and open to registration for people all around the world that want to participate in higher education courses; they are recognized for their educational quality and flexibility schedules
                <sup>
                    <xref ref-type="bibr" rid="ref-4">4</xref>,
                    <xref ref-type="bibr" rid="ref-5">5</xref>
                </sup>. MOOCs materials are free of charge, however, in some courses one can pay to get a certificate of completion
                <sup>
                    <xref ref-type="bibr" rid="ref-4">4</xref>,
                    <xref ref-type="bibr" rid="ref-5">5</xref>
                </sup>.</p>
            <p>They represent one strategy to reduce costs and enable continuous education in developing countries; especially learners with English language proficiency, computer literacy, and internet access
                <sup>
                    <xref ref-type="bibr" rid="ref-5">5</xref>
                </sup>. This study aimed to identify the characteristics of MOOCs related to biomedical informatics.</p>
        </sec>
        <sec sec-type="methods">
            <title>Methods</title>
            <p>A search of MOOCs was performed in several learning platforms, including 
                <ext-link ext-link-type="uri" xlink:href="https://www.coursera.org/">Coursera</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://www.edx.org/">EdX</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://www.futurelearn.com/">FutureLearn</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://eu.udacity.com/nanodegree?gclid=CjwKCAiAyfvhBRBsEiwAe2t_i6tu3IHY-VhV9yLi39_BsD0YsHghP9XW6S9R6DJoDL8kjl38QEDIyRoCKSIQAvD_BwE">Udacity</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://www.fun-mooc.fr/">FunMOOC</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://unimooc.com/">UniMOOC</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://miriadax.net/web/general-navigation/cursos">MiriadaX</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://alison.com/">Alison</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://iversity.org/">Iversity</ext-link>&#x00ae;, 
                <ext-link ext-link-type="uri" xlink:href="https://www.open2study.com/">Open2Study</ext-link>&#x00ae; and 
                <ext-link ext-link-type="uri" xlink:href="https://www.p2pu.org/en/">P2PU</ext-link>&#x00ae;, in order to find courses about biomedical informatics. The search was made from 31 October to 27 November, 2018. The following keywords were used: biomedical informatics, telemedicine, telehealth, remote consultation, mobile health, mHealth, eHealth, medicine technology, biomedical technology, IT Health and bioinformatics.</p>
            <p>Information was obtained on the platform where the MOOC was hosted, data regarding the institution offering the course, and the original language. The disciplines were categorized into: Bioinformatics, Images, Clinical Informatics, Public Health Informatics and Data science (a course could approach more than one discipline). Likewise, the data of the duration of the course and its cost in dollars were also obtained.</p>
            <p>The data obtained were analyzed in 
                <ext-link ext-link-type="uri" xlink:href="https://www.stata.com/">STATA</ext-link> version 14. The categorical results were reported by frequencies and percentages, while the numerical results were reported by measures of central tendency and dispersion, after analysis of normality using the Shapiro-Wilk test.</p>
        </sec>
        <sec sec-type="results">
            <title>Results</title>
            <p>The analyses of the data identified 67 MOOCs offered on biomedical informatics in the world. The majority (71.64%) were offered by Coursera, followed by EdX (13.43%) and FutureLearn (13.43%). The majority of MOOCs were offered from institutes from the United State of America (73.13%). Out of these, the majority were offered by universities. The large majority of these MOOCs, were offered by the University of California San Diego, followed by Johns Hopkins University. Finally the language breakdown of MOOCs related to biomedical informatics shows that the vast majority of MOOCs ( 95.52%) were offered in English (
                <xref ref-type="table" rid="T1">Table 1</xref>). The details of each course are shown in the 
                <xref ref-type="table" rid="T2">Table 2</xref>.</p>
            <table-wrap id="T1" orientation="portrait" position="anchor">
                <label>Table 1. </label>
                <caption>
                    <title>Characteristics of massive open online courses about biomedical informatics.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th colspan="1" rowspan="1"/>
                            <th align="center" colspan="1" rowspan="1">(N =67)</th>
                            <th align="center" colspan="1" rowspan="1">%</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">
                                <bold>Plataform</bold>
</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Coursera</td>
                            <td align="center" colspan="1" rowspan="1">48</td>
                            <td align="center" colspan="1" rowspan="1">71.64</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;EdX</td>
                            <td align="center" colspan="1" rowspan="1">9</td>
                            <td align="center" colspan="1" rowspan="1">13.43</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;FutureLearn</td>
                            <td align="center" colspan="1" rowspan="1">9</td>
                            <td align="center" colspan="1" rowspan="1">13.43</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Udacity</td>
                            <td align="center" colspan="1" rowspan="1">1</td>
                            <td align="center" colspan="1" rowspan="1">1.49</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">
                                <bold>Country</bold>
</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;United States of America</td>
                            <td align="center" colspan="1" rowspan="1">49</td>
                            <td align="center" colspan="1" rowspan="1">73.13</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;China</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;United Kingdom</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Russia</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Denmark</td>
                            <td align="center" colspan="1" rowspan="1">2</td>
                            <td align="center" colspan="1" rowspan="1">2.99</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Netherland</td>
                            <td align="center" colspan="1" rowspan="1">2</td>
                            <td align="center" colspan="1" rowspan="1">2.99</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Others</td>
                            <td align="center" colspan="1" rowspan="1">5</td>
                            <td align="center" colspan="1" rowspan="1">7.46</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">
                                <bold>University</bold>
                            </td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Yes</td>
                            <td align="center" colspan="1" rowspan="1">63</td>
                            <td align="center" colspan="1" rowspan="1">94.03</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;No</td>
                            <td align="center" colspan="1" rowspan="1">4</td>
                            <td align="center" colspan="1" rowspan="1">5.97</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">
                                <bold>Institutions</bold>
                            </td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;University of California San Diego</td>
                            <td align="center" colspan="1" rowspan="1">14</td>
                            <td align="center" colspan="1" rowspan="1">20.90</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Johns Hopkins University</td>
                            <td align="center" colspan="1" rowspan="1">8</td>
                            <td align="center" colspan="1" rowspan="1">11.94</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Icahn School of Medicine at Mount Sinai</td>
                            <td align="center" colspan="1" rowspan="1">6</td>
                            <td align="center" colspan="1" rowspan="1">8.98</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Columbia University</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Georgia Institute of Technology</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;University of Illinois</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Others</td>
                            <td align="center" colspan="1" rowspan="1">30</td>
                            <td align="center" colspan="1" rowspan="1">44.74</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">
                                <bold>Original lenguaje</bold>
                            </td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;English</td>
                            <td align="center" colspan="1" rowspan="1">64</td>
                            <td align="center" colspan="1" rowspan="1">95.52</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1">&#x00a0;&#x00a0;&#x00a0;&#x00a0;Ruso</td>
                            <td align="center" colspan="1" rowspan="1">3</td>
                            <td align="center" colspan="1" rowspan="1">4.48</td>
                        </tr>
                    </tbody>
                </table>
            </table-wrap>
            <table-wrap id="T2" orientation="portrait" position="anchor">
                <label>Table 2. </label>
                <caption>
                    <title>Characteristics of each massive open online course on biomedical informatics.</title>
                </caption>
                <table content-type="article-table" frame="hsides">
                    <thead>
                        <tr>
                            <th align="left" colspan="1" rowspan="2" valign="top">ID</th>
                            <th align="left" colspan="1" rowspan="2" valign="top">Platform</th>
                            <th align="left" colspan="1" rowspan="2" valign="top">Course name</th>
                            <th align="left" colspan="1" rowspan="2" valign="top">Institution</th>
                            <th align="left" colspan="1" rowspan="2" valign="top">Lenguage
                                <break/>(Subtitle)</th>
                            <th align="center" colspan="5" rowspan="1" valign="top">Topic</th>
                        </tr>
                        <tr>
                            <th align="center" colspan="1" rowspan="1" valign="top">Bioinformatics</th>
                            <th align="center" colspan="1" rowspan="1" valign="top">Images</th>
                            <th align="center" colspan="1" rowspan="1" valign="top">Clinic</th>
                            <th align="center" colspan="1" rowspan="1" valign="top">Public
                                <break/>health</th>
                            <th align="center" colspan="1" rowspan="1" valign="top">Data
                                <break/>Science</th>
                        </tr>
                    </thead>
                    <tbody>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">1</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Algorithms for DNA
                                <break/>Sequencing</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">2</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Algorithms on Strings</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">3</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Analysis of Algorithms</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Princeton
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">4</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Basics of Extracellular
                                <break/>Vesicles</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California,
                                <break/>Irvine</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">5</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Big Data Science
                                <break/>with the BD2K-LINCS
                                <break/>Data Coordination and
                                <break/>Integration Center</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">6</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Big Data, Genes, and
                                <break/>Medicine</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>New York</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">7</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioconductor for
                                <break/>Genomic Data Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">8</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioinformatic Methods I</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>Toronto</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">9</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioinformatic Methods II</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">10</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioinformatics Capstone:
                                <break/>Big Data in Biology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">11</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioinformatics:
                                <break/>Introduction and Methods
                                <break/>生物信息学: 导论与方法</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Peking
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">12</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Biology Meets
                                <break/>Programming:
                                <break/>Bioinformatics for
                                <break/>Beginners</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Portuguese)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">13</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Command Line Tools for
                                <break/>Genomic Data Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">14</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Comparing Genes,
                                <break/>Proteins, and Genomes
                                <break/>(Bioinformatics III)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">15</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Data Science in Stratified
                                <break/>Healthcare and Precision
                                <break/>Medicine</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">The University
                                <break/>of Edinburgh</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">16</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Dynamical Modeling
                                <break/>Methods for Systems
                                <break/>Biology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">17</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">eHealth: More than just
                                <break/>an electronic record</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">The University
                                <break/>of Sydney</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">18</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Finding Hidden
                                <break/>Messages in DNA
                                <break/>(Bioinformatics I)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">19</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Finding Mutations in
                                <break/>DNA and Proteins
                                <break/>(Bioinformatics VI)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">20</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genome Assembly
                                <break/>Programming Challenge</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">21</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genome Sequencing
                                <break/>(Bioinformatics II)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">22</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genomic Data Science
                                <break/>and Clustering
                                <break/>(Bioinformatics V)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">23</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genomic Data Science
                                <break/>Capstone</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">24</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genomic Data Science
                                <break/>with Galaxy</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">25</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Genomics: Decoding
                                <break/>the Universal Language
                                <break/>of Life</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University
                                <break/>of Illinois
                                <break/>at Urbana-
                                <break/>Champaign</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">26</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Health Care IT:
                                <break/>Challenges and
                                <break/>Opportunities</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">27</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Health Informatics on
                                <break/>FHIR</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Georgia
                                <break/>Institute of
                                <break/>Technology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">28</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">HI-FIVE: Health
                                <break/>Informatics For
                                <break/>Innovation, Value
                                <break/>&amp; Enrichment
                                <break/>(Administrative/IT
                                <break/>Perspective)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Columbia
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">29</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">HI-FIVE: Health
                                <break/>Informatics For
                                <break/>Innovation, Value &amp;
                                <break/>Enrichment (Clinical
                                <break/>Perspective)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Columbia
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">30</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">HI-FIVE: Health
                                <break/>Informatics For
                                <break/>Innovation, Value &amp;
                                <break/>Enrichment (Social/Peer
                                <break/>Perspective)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Columbia
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">31</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Integrated Analysis in
                                <break/>Systems Biology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">32</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Interprofessional
                                <break/>Healthcare Informatics</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University
                                <break/>of Minnesota</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">33</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Introduction to Genomic
                                <break/>Technologies</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">34</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Julia Scientific
                                <break/>Programming</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>Cape Town</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">35</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Mathematical Thinking in
                                <break/>Computer Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">36</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Metagenomics applied to
                                <break/>surveillance of pathogens
                                <break/>and antimicrobial
                                <break/>resistance</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Technical
                                <break/>University of
                                <break/>Denmark</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">37</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Molecular Evolution
                                <break/>(Bioinformatics IV)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">38</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Network Analysis in
                                <break/>Systems Biology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Icahn School
                                <break/>of Medicine at
                                <break/>Mount Sinai</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">39</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Pattern Discovery in Data
                                <break/>Mining</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University
                                <break/>of Illinois
                                <break/>at Urbana-
                                <break/>Champaign</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">40</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Programa especializado
                                <break/>Bioinformatics</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Chinese)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">41</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Programa especializado
                                <break/>Data Mining</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University
                                <break/>of Illinois
                                <break/>at Urbana-
                                <break/>Champaign</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">42</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Programa especializado
                                <break/>Data Structures and
                                <break/>Algorithms</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Spanish)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">43</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Programa especializado
                                <break/>Genomic Data Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Russian)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">44</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Programa especializado
                                <break/>&#x041c;&#x0430;&#x0448;&#x0438;&#x043d;&#x043d;&#x043e;&#x0435; &#x043e;&#x0431;&#x0443;&#x0447;&#x0435;&#x043d;&#x0438;&#x0435; &#x0438;
                                <break/>&#x0430;&#x043d;&#x0430;&#x043b;&#x0438;&#x0437; &#x0434;&#x0430;&#x043d;&#x043d;&#x044b;&#x0445;</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Moscow
                                <break/>Institute of
                                <break/>Physics and
                                <break/>Technology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Ruso
                                <break/>(Russian)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">45</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Python for Genomic Data
                                <break/>Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Johns Hopkins
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/> (English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">46</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Whole genome
                                <break/>sequencing of bacterial
                                <break/>genomes - tools and
                                <break/>applications</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Technical
                                <break/>University of
                                <break/>Denmark - DTU</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">47</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x0412;&#x0432;&#x0435;&#x0434;&#x0435;&#x043d;&#x0438;&#x0435; &#x0432;
                                <break/>&#x0431;&#x0438;&#x043e;&#x0438;&#x043d;&#x0444;&#x043e;&#x0440;&#x043c;&#x0430;&#x0442;&#x0438;&#x043a;&#x0443;
                                <break/>(Introduction to
                                <break/>Bioinformatics)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Saint
                                <break/>Petersburg
                                <break/>State University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Russian
                                <break/>(Russian)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">48</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Coursera</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">&#x0412;&#x0432;&#x0435;&#x0434;&#x0435;&#x043d;&#x0438;&#x0435; &#x0432;
                                <break/>&#x0411;&#x0438;&#x043e;&#x0438;&#x043d;&#x0444;&#x043e;&#x0440;&#x043c;&#x0430;&#x0442;&#x0438;&#x043a;&#x0443;:
                                <break/>&#x041c;&#x0435;&#x0442;&#x0430;&#x0433;&#x0435;&#x043d;&#x043e;&#x043c;&#x0438;&#x043a;&#x0430;
                                <break/>(Introduction to
                                <break/>Bioinformatics:
                                <break/>Metagenomics)</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Saint
                                <break/>Petersburg
                                <break/>State University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Russian
                                <break/>(Russian,
                                <break/>English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">49</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Big Data Analytics in
                                <break/>Healthcare</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Georgia
                                <break/>Institute of
                                <break/>Technology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">50</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bioinformatics</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>maryland</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">51</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Data Analytics in
                                <break/>Health &#x2013; From Basics to
                                <break/>Business</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">KU Leuven
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">52</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Demystifying Biomedical
                                <break/>Big Data: A User&#x2019;s Guide</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Georgetown
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">53</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">eHealth &#x2013; Opportunities
                                <break/>and Challenges</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Karolinska
                                <break/>Institutet</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">54</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Global Health Informatics
                                <break/>to Improve Quality of
                                <break/>Care</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Massachusetts
                                <break/> Institute of
                                <break/>Technology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">55</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Introduction to Genomic
                                <break/>Data Science</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>California San
                                <break/>Diego</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">56</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Medicine in the Digital
                                <break/>Age</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Rice University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">57</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EdX</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Trends in e-Psychology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">KU Leuven
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">58</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Bacterial Genomes: From
                                <break/>DNA to Protein Function
                                <break/>Using Bioinformatics</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Wellcome
                                <break/>Genome
                                <break/>Campus
                                <break/>Advanced
                                <break/>Courses and
                                <break/>Scientific
                                <break/>Conferences</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">59</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Clinical Bioinformatics:
                                <break/>Unlocking Genomics in
                                <break/>Healthcare</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">The University
                                <break/>of Manchester</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">60</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Data Science for
                                <break/>Healthcare: Using Real
                                <break/>World Evidence</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EIT HEALTH</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">61</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Digital Health for Cancer
                                <break/>Management: Smart
                                <break/>Health Technologies in
                                <break/>Complex Diseases</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Taipei Medical
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Chinese)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">62</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">eHealth: Combining
                                <break/>Psychology, Technology
                                <break/>and Health</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>Twente</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">63</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Health Data and Analytics</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">EIT HEALTH</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">64</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Protecting Health Data in
                                <break/>the Modern Age: Getting
                                <break/>to Grips with the GDP</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>Groningen</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">65</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Social Media in
                                <break/>Healthcare: Opportunities
                                <break/>and Challenges</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Taipei Medical
                                <break/>University</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English,
                                <break/>Chinese)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">66</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">FutureLearn</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">The Power of Data in
                                <break/>Health and Social Care</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">University of
                                <break/>Strathclyde</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                        <tr>
                            <td align="left" colspan="1" rowspan="1" valign="top">67</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Udacity</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Health Informatics in the
                                <break/>Cloud</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">Georgia
                                <break/>Institute of
                                <break/>Technology</td>
                            <td align="left" colspan="1" rowspan="1" valign="top">English
                                <break/>(English)</td>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td colspan="1" rowspan="1"/>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                            <td align="center" colspan="1" rowspan="1" valign="top">X</td>
                        </tr>
                    </tbody>
                </table>
            </table-wrap>
            <p>From the MOOCs, disciplines related to biomedical informatics courses were analyzed. Some courses taught more than one subject at a time. The majority of these MOOCs, 56.72% (n = 38), were in bioinformatics and 47.76% (n = 32) in data science (
                <xref ref-type="fig" rid="f1">Figure 1</xref>).</p>
            <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                <label>Figure 1. </label>
                <caption>
                    <title>Disciplines addressed in MOOCs on biomedical informatics.</title>
                </caption>
                <graphic orientation="portrait" position="float" xlink:href="https://f1000research-files.f1000.com/manuscripts/19345/0d86df87-5085-42fb-9607-d514ec644187_figure1.gif"/>
            </fig>
            <p>The average cost of the courses was $49, which ranged from zero cost (free) to $672. Likewise, the average length of the MOOCs considered for the review was 5 weeks (Min: 2, Max: 36), with an average activity of 3 hours per week (Min: 1, Max: 30).</p>
        </sec>
        <sec sec-type="discussion">
            <title>Discussion</title>
            <p>Within the educational platforms, Coursera&#x00ae; offered the majority of courses focused on BI, as showed in a previous study of health and medicine
                <sup>
                    <xref ref-type="bibr" rid="ref-5">5</xref>
                </sup>; authors prefer to upload their content more often in Coursera&#x00ae; because this is the most used platform
                <sup>
                    <xref ref-type="bibr" rid="ref-6">6</xref>
                </sup>.</p>
            <p>Regarding the countries, The United States, China, and the United Kingdom develop the majority of courses. There appears to be a correlation between countries that generate more MOOCs and those with higher scientific output
                <sup>
                    <xref ref-type="bibr" rid="ref-7">7</xref>
                </sup>. It&#x2019;s important to consider that Russia appears among the leading developers of MOOCs; this could be explained by the student exchanges that the Russian educational institutions have been promoting
                <sup>
                    <xref ref-type="bibr" rid="ref-8">8</xref>
                </sup>.</p>
            <p>The majority of courses were offered in English, with a few having subtitles in other languages such as in previous studies
                <sup>
                    <xref ref-type="bibr" rid="ref-9">9</xref>
                </sup>. A possible explanation for this might be the vast majority of them were made in an English-speaking country. Another explanation could be the development level of BI in these countries.</p>
            <p>Most courses approached both bioinformatics and data science, maybe because both are tools to personalized medicine and this was been a growing field in the last few years
                <sup>
                    <xref ref-type="bibr" rid="ref-10">10</xref>
                </sup>. Therefore it is necessary to develop more courses focused on health informatics.</p>
            <p>This study has some limitations, such as such as only English language courses being included, and the incomplete coverage of all MOOC platforms. However, the platforms studied are those that have the most health or medicine courses
                <sup>
                    <xref ref-type="bibr" rid="ref-5">5</xref>
                </sup>. This is the first study that has assessed MOOCs in the area of BI. In addition, the data shows a list with all the names, languages and prices of the courses.</p>
            <p>The recommendation of this study is to diversify the BI courses into other disciplines. We suggest further studies in this area that focus on evaluating the quality of MOOCs.</p>
        </sec>
        <sec sec-type="conclusions">
            <title>Conclusion</title>
            <p>The majority of MOOCs on Biomedical informatics were focused in bioinformatics and data science, they were offered in English by institutions in the developing world.</p>
        </sec>
        <sec>
            <title>Data availability</title>
            <p>Underlying data is available from figshare</p>
            <p>Figshare: Dataset 1. Data base of Massive Open Online Courses on Biomedical Informatics 
                <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.7582016.v2">https://doi.org/10.6084/m9.figshare.7582016.v2</ext-link>
                <sup>
                    <xref ref-type="bibr" rid="ref-11">11</xref>
                </sup>
            </p>
            <p>Licence: 
                <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 Universal</ext-link>
            </p>
        </sec>
    </body>
    <back>
        <ref-list>
            <ref id="ref-1">
                <label>1</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Kulikowski</surname>
                            <given-names>CA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Shortliffe</surname>
                            <given-names>EH</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Currie</surname>
                            <given-names>LM</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>AMIA Board white paper: definition of biomedical informatics and specification of core competencies for graduate education in the discipline.</article-title>
                    <source>

                        <italic toggle="yes">J Am Med Inform Assoc.</italic>
</source>
                    <year>2012</year>;<volume>19</volume>(<issue>6</issue>):<fpage>931</fpage>&#x2013;<lpage>8</lpage>.
                    <pub-id pub-id-type="pmid">22683918</pub-id>
                    <pub-id pub-id-type="doi">10.1136/amiajnl-2012-001053</pub-id>
                    <pub-id pub-id-type="pmcid">3534470</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-2">
                <label>2</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Mantas</surname>
                            <given-names>J</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Ammenwerth</surname>
                            <given-names>E</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Demiris</surname>
                            <given-names>G</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Recommendations of the International Medical Informatics Association (IMIA) on Education in Biomedical and Health Informatics.</article-title>
                    <source>

                        <italic toggle="yes">Methods Inf Med.</italic>
</source>
                    <year>2010</year>;<volume>49</volume>(<issue>2</issue>):<fpage>105</fpage>&#x2013;<lpage>20</lpage>.
                    <pub-id pub-id-type="pmid">20054502</pub-id>
                    <pub-id pub-id-type="doi">10.3414/ME5119</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-3">
                <label>3</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Blas</surname>
                            <given-names>MM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Curioso</surname>
                            <given-names>WH</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Garcia</surname>
                            <given-names>PJ</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Training the biomedical informatics workforce in Latin America: results of a needs assessment.</article-title>
                    <source>

                        <italic toggle="yes">BMJ Open.</italic>
</source>
                    <year>2011</year>;<volume>1</volume>(<issue>2</issue>):<fpage>e000233</fpage>.
                    <pub-id pub-id-type="pmid">22080537</pub-id>
                    <pub-id pub-id-type="doi">10.1136/bmjopen-2011-000233</pub-id>
                    <pub-id pub-id-type="pmcid">3208899</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-4">
                <label>4</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Pickering</surname>
                            <given-names>JD</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Swinnerton</surname>
                            <given-names>BJ</given-names>
                        </name>
</person-group>:
                    <article-title>An Anatomy Massive Open Online Course as a Continuing Professional Development Tool for Healthcare Professionals.</article-title>
                    <source>

                        <italic toggle="yes">Med Sci Educ.</italic>
</source>
                    <year>2017</year>;<volume>27</volume>(<issue>2</issue>):<fpage>243</fpage>&#x2013;<lpage>52</lpage>.
                    <pub-id pub-id-type="doi">10.1007/s40670-017-0383-7</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-5">
                <label>5</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Liyanagunawardena</surname>
                            <given-names>TR</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Williams</surname>
                            <given-names>SA</given-names>
                        </name>
</person-group>:
                    <article-title>Massive open online courses on health and medicine: review.</article-title>
                    <source>

                        <italic toggle="yes">J Med Internet Res.</italic>
</source>
                    <year>2014</year>;<volume>16</volume>(<issue>8</issue>):<fpage>e191</fpage>.
                    <pub-id pub-id-type="pmid">25123952</pub-id>
                    <pub-id pub-id-type="doi">10.2196/jmir.3439</pub-id>
                    <pub-id pub-id-type="pmcid">4155756</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-6">
                <label>6</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Anggraini</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>tanuwijaya</surname>
                            <given-names>C</given-names>
                        </name>

                        <name name-style="western">
                            <surname>oktavia</surname>
                            <given-names>T</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Analyzing MOOC Features for Enhancing Students Learning Satisfaction.</article-title>
                    <source>

                        <italic toggle="yes">Journal of Telecommunication, Electronic and Computer Engineering.</italic>
</source>
                    <year>2018</year>;<volume>10</volume>(<issue>4</issue>).
                    <ext-link ext-link-type="uri" xlink:href="http://journal.utem.edu.my/index.php/jtec/article/view/3578">Reference Source</ext-link>
                </mixed-citation>
            </ref>
            <ref id="ref-7">
                <label>7</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Scimago</surname>
                            <given-names>Lab</given-names>
                        </name>
</person-group>:
                    <article-title>Ranking countries.</article-title>
                    <source>

                        <italic toggle="yes">Scimago Journal Rank.</italic>
</source>[Cited on: 12-12-2018].
                    <ext-link ext-link-type="uri" xlink:href="https://www.scimagojr.com/countryrank.php">Reference Source</ext-link>
                </mixed-citation>
            </ref>
            <ref id="ref-8">
                <label>8</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Ziganshin</surname>
                            <given-names>BA</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Sadigh</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Yausheva</surname>
                            <given-names>LM</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Developing medical education capacity in Russia: twenty years of experience.</article-title>
                    <source>

                        <italic toggle="yes">BMC Med Educ.</italic>
</source>
                    <year>2017</year>;<volume>17</volume>(<issue>1</issue>):<fpage>24</fpage>.
                    <pub-id pub-id-type="pmid">28122550</pub-id>
                    <pub-id pub-id-type="doi">10.1186/s12909-017-0861-z</pub-id>
                    <pub-id pub-id-type="pmcid">5267488</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-9">
                <label>9</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Culquichic&#x00f3;n</surname>
                            <given-names>C</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Helguero-Santin</surname>
                            <given-names>LM</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Lab&#x00e1;n-Seminario</surname>
                            <given-names>LM</given-names>
                        </name>

                        <etal/>
</person-group>:
                    <article-title>Massive open online courses in health sciences from Latin American institutions: A need for improvement? [version 1; referees: 2 approved].</article-title>
                    <source>

                        <italic toggle="yes">F1000Res.</italic>
</source>
                    <year>2017</year>;<volume>6</volume>:<fpage>940</fpage>.
                    <pub-id pub-id-type="pmid">28713560</pub-id>
                    <pub-id pub-id-type="doi">10.12688/f1000research.11626.1</pub-id>
                    <pub-id pub-id-type="pmcid">5499794</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-10">
                <label>10</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Alyass</surname>
                            <given-names>A</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Turcotte</surname>
                            <given-names>M</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Meyre</surname>
                            <given-names>D</given-names>
                        </name>
</person-group>:
                    <article-title>From big data analysis to personalized medicine for all: challenges and opportunities.</article-title>
                    <source>

                        <italic toggle="yes">BMC Med Genomics.</italic>
</source>
                    <year>2015</year>;<volume>8</volume>:<fpage>33</fpage>.
                    <pub-id pub-id-type="pmid">26112054</pub-id>
                    <pub-id pub-id-type="doi">10.1186/s12920-015-0108-y</pub-id>
                    <pub-id pub-id-type="pmcid">4482045</pub-id>
                </mixed-citation>
            </ref>
            <ref id="ref-11">
                <label>11</label>
                <mixed-citation publication-type="journal">
                    <person-group person-group-type="author">

                        <name name-style="western">
                            <surname>Moquillaza Alc&#x00e1;ntara</surname>
                            <given-names>VH</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Arapa Apaza</surname>
                            <given-names>KL</given-names>
                        </name>

                        <name name-style="western">
                            <surname>Quispe-Juli</surname>
                            <given-names>CU</given-names>
                        </name>
</person-group>:
                    <article-title>Data base of Massive Open Online Courses on Biomedical Informatics</article-title>.<year>2019</year>.
                    <ext-link ext-link-type="uri" xlink:href="http://www.doi.org/10.6084/m9.figshare.7582016.v2">http://www.doi.org/10.6084/m9.figshare.7582016.v2</ext-link>
                </mixed-citation>
            </ref>
        </ref-list>
    </back>
    <sub-article article-type="reviewer-report" id="report44480">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.19345.r44480</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Liyanagunawardena</surname>
                        <given-names>Tharindu</given-names>
                    </name>
                    <xref ref-type="aff" rid="r44480a1">1</xref>
                    <role>Referee</role>
                </contrib>
                <aff id="r44480a1">
                    <label>1</label>University College of Estate Managment, Reading, UK</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>25</day>
                <month>2</month>
                <year>2019</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2019 Liyanagunawardena T</copyright-statement>
                <copyright-year>2019</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport44480" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.17693.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>This study aimed to identify the characteristics of MOOCs related to biomedical informatics and it was an interesting read. However, there are some serious issues in the presentation of this work. I find some of the sentences difficult to parse. For example, Introduction - second sentence, Introduction - second paragraph, first sentence. Overall, I think a professional proof reading would improve the article's readability considerably.</p>
            <p> &#x00a0; 
                <list list-type="bullet">
                    <list-item>
                        <p>This study has searched for MOOCs using many well-known MOOC platforms. It would have improved the search had the search included MOOC aggregation service for searching.</p>
                    </list-item>
                    <list-item>
                        <p>In the Results section it is claimed that "67 MOOCs offered on biomedical informatics in the world" - I think this needs to account for the&#x00a0;methodology and scale back to what the search was - selected platforms.</p>
                    </list-item>
                    <list-item>
                        <p>It is a little confusing to hear about the "average cost of courses" given that the searches were on MOOCs and whether&#x00a0;these were fees to access the course materials or for certification.</p>
                    </list-item>
                    <list-item>
                        <p>The authors need to acknowledge that major non-English MOOC platforms such as&#x00a0;Edraak and XuetangX were not consulted in this search when making statements about course languages.</p>
                    </list-item>
                    <list-item>
                        <p>"However, the platforms studied are those that have the most health or medicine courses
                            <sup>5</sup>" - can this statement be substantiated?</p>
                    </list-item>
                    <list-item>
                        <p>"This is the first study that has assessed MOOCs in the area of BI" - can this be substantiated?</p>
                    </list-item>
                </list> I find the conclusion "The majority of MOOCs on Biomedical informatics were focused in bioinformatics and data science,&#x00a0;they were offered in English by institutions in the developing world" not supported by the evidence and misleading.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>I cannot comment. A qualified statistician is required.</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Partly</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Partly</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>No</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Learning Technology, MOOCs, OERs, Accessibility</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
    </sub-article>
    <sub-article article-type="reviewer-report" id="report44479">
        <front-stub>
            <article-id pub-id-type="doi">10.5256/f1000research.19345.r44479</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Meinert</surname>
                        <given-names>Edward</given-names>
                    </name>
                    <xref ref-type="aff" rid="r44479a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-2484-3347</uri>
                </contrib>
                <aff id="r44479a1">
                    <label>1</label>Healthcare Translation Research Group, Department of Paediatrics, University of Oxford, Oxford, UK</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>15</day>
                <month>2</month>
                <year>2019</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2019 Meinert E</copyright-statement>
                <copyright-year>2019</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport44479" related-article-type="peer-reviewed-article" xlink:href="10.12688/f1000research.17693.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>reject</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>The authors have developed a manuscript examining the use of biomedical informatics in current MOOC implementations. This contribution could be very useful for those looking to examine MOOC implementations in this subject domain.</p>
            <p> </p>
            <p> There are a few areas I believe the authors could further develop to improve the work:</p>
            <p> </p>
            <p> 1. While the manuscript introduces the subject matter, there is not background for why the course of investigation is merited. There is most likely a clear rationale for this investigation, the authors could improve the manuscript to provide it.</p>
            <p> </p>
            <p> 2. Methodologically the authors have not provided details on data extraction methods nor how their keywords were classified and harmonised among the various MOOC platforms. Additionally, to be medical literature, it would have been useful to use a systematic search method applied with this context as this would be more familiar to readers.</p>
            <p> </p>
            <p> 3. The authors examine cost, number of implementations and further classifications. In their own right, these are big areas and the authors would do well to consider analysis and comparison of factors of economic impact, learning design, etc - the current discussion and analysis is only approaching these areas at a superficial interpretive level.</p>
            <p> </p>
            <p> I recommend the authors address the rationale, strengthen the methodological approach and pick particular areas of analysis to strengthen the richness of this manuscript.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Partly</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Partly</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>No</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Partly</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Partly</p>
            <p>Reviewer Expertise:</p>
            <p>Digital health; eLearning</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above.</p>
        </body>
    </sub-article>
</article>
