Eculizumab is an effective treatment for atypical hemolytic uremic syndrome (aHUS) in patients with or without identified genetic complement mutations or complement factor H autoantibodies
Eculizumab is an effective treatment for atypical hemolytic uremic syndrome (aHUS) in patients with or without identified genetic complement mutations or complement factor H autoantibodies
[version 1; not peer reviewed]Dr. Licht has received fees for consultancy, research funding, and honoraria from Alexion Pharmaceuticals. Dr. Muus has been a member of an advisory board for Alexion Pharmaceuticals. Dr. Legendre has received compensation for participation in a speakers' bureau for Alexion Pharmaceuticals. Dr. Goodship has received research funding, honoraria, and compensation for participation in a speakers' bureau from Alexion Pharmaceuticals and has been a member of an advisory board for Alexion Pharmaceuticals. Dr. Bedrosian is an employee of Alexion Pharmaceuticals. Dr. Loirat has been a coordinator of eculizumab trials for, and received honoraria for conferences from, Alexion Pharmaceuticals. Drs. Al-Akash, Smith, and Bacchi have no financial relationships to disclose. This study was sponsored by Alexion Pharmaceuticals, Inc. Editorial support was provided by John Kincaid, MD, of Alexion Pharmaceuticals, Inc. Medical writing support was provided by Infusion Communications and supported by Alexion Pharmaceuticals, Inc.
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