<p>Four-factor prothrombin complex concentrate (4F-PCC) reverses bleeding associated with the new direct oral anticoagulants (NOACs) dabigatran, rivaroxaban, edoxaban and apixaban in a rabbit model</p>

Eva Herzog; Franz Kaspereit; Wilfried Krege; Jochen Mueller-Cohrs; Baerbel Doerr; Peter Niebl; Gerhard Dickneite

doi:10.7490/f1000research.1110793.1

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Herzog E, Kaspereit F, Krege W et al. Four-factor prothrombin complex concentrate (4F-PCC) reverses bleeding associated with the new direct oral anticoagulants (NOACs) dabigatran, rivaroxaban, edoxaban and apixaban in a rabbit model [version 1; not peer reviewed]. F1000Research 2015, 4:1051 (poster) (https://doi.org/10.7490/f1000research.1110793.1)

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Four-factor prothrombin complex concentrate (4F-PCC) reverses bleeding associated with the new direct oral anticoagulants (NOACs) dabigatran, rivaroxaban, edoxaban and apixaban in a rabbit model

Eva Herzog¹, Franz Kaspereit, Wilfried Krege, Jochen Mueller-Cohrs, Baerbel Doerr, Peter Niebl, Gerhard Dickneite

Published 12 Oct 2015 (https://doi.org/10.7490/f1000research.1110793.1)

Author Affiliations

¹ Department of Pharmacology and Toxicology, Research, CSL Behring GmbH, Marburg, Germany

Copyright © 2015 Herzog E et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CITE

Published 12 Oct 2015

Four-factor prothrombin complex concentrate (4F-PCC) reverses bleeding associated with the new direct oral anticoagulants (NOACs) dabigatran, rivaroxaban, edoxaban and apixaban in a rabbit model
[version 1; not peer reviewed]

Eva Herzog¹, Franz Kaspereit, Wilfried Krege, Jochen Mueller-Cohrs, Baerbel Doerr, Peter Niebl, Gerhard Dickneite

Author Affiliations

¹ Department of Pharmacology and Toxicology, Research, CSL Behring GmbH, Marburg, Germany

Presented at

The International Society on Thrombosis and Haemostasis (ISTH) Congress 2015

Abstract

Competing Interests

Authors are employees of CSL Behring GmbH.

Keywords

new direct oral anticoagulants, coagulation parameters

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