<p>Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus</p>

Hong Zheng; Aditya M Rao; Denis Dermadi; Jiaying Toh; Lara  Murphy Jones; Michele Donato; Yiran Liu; Yapeng Su; Cheng Dai; Sergey Kornilov; Minas Karagiannis; Theodoros Marantos; Yehudit Hasin-Brumshtein; Yudong He; Evangelos J Giamarellos-Bourboulis; Jim Heath; Purvesh Khatri

doi:10.7490/f1000research.1118410.1

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Zheng H, Rao AM, Dermadi D et al. Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus [version 1; not peer reviewed]. F1000Research 2020, 9:1410 (poster) (https://doi.org/10.7490/f1000research.1118410.1)

NOTE: it is important to ensure the information in square brackets after the title is included in this citation.

Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus

Hong Zheng, Aditya M Rao, Denis Dermadi, Jiaying Toh, Lara Murphy Jones, Michele Donato, Yiran Liu, Yapeng Su, Cheng Dai, Sergey Kornilov, Minas Karagiannis, Theodoros Marantos, Yehudit Hasin-Brumshtein, Yudong He, Evangelos J Giamarellos-Bourboulis, Jim Heath, Purvesh Khatri¹

Published 06 Dec 2020 (https://doi.org/10.7490/f1000research.1118410.1)

Author Affiliations

¹ Stanford University School of Medicine, USA

Copyright © 2020 Zheng H et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CITE

Published 06 Dec 2020

Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus
[version 1; not peer reviewed]

Author Affiliations

¹ Stanford University School of Medicine, USA

Abstract

Competing Interests

EJGB has received honoraria from Abbott CH, Angelini Italy, bioMerieux Inc, InflaRx GmbH, MSD Greece, and XBiotech Inc.; independent educational grants from AbbVie, Abbott, Astellas Pharma Europe, AxisShield, bioMerieux Inc, InflaRx GmbH, ThermoFisher Brahms GmbH, and XBiotech Inc; and funding from the FrameWork 7 program HemoSpec (granted to the National and Kapodistrian University of Athens), the Horizon2020 Marie-Curie Project European Sepsis Academy (granted to the National and Kapodistrian University of Athens), and the Horizon 2020 European Grant ImmunoSep (granted to the Hellenic Institute for the Study of Sepsis). PK is a shareholder and a consultant to Inflammatix, Inc. YH and YH are employees of, and stockholders in, Inflammatix, Inc.

Keywords

pandemic preparedness, conserved host immune response, multi-cohort systems immunology analysis, protective immune response to viral infection, myeloid derived suppressor cells, trajectory of viral infection

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