Monitoring of awake bruxism by intelligent app

Byron Velásquez Ron; Verónica Mosquera Cisneros; Pamela Pazmiño Troncoso; María Rodríguez Tates; Eddy Alvares Lalvay; Luis Chauca Bajaña; Andrea Ordoñez Balladares

doi:10.12688/f1000research.110673.2

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Systematic Review

Revised

Monitoring of awake bruxism by intelligent app

[version 2; peer review: 2 approved]

Byron Velásquez Ron ¹, Verónica Mosquera Cisneros¹, Pamela Pazmiño Troncoso¹, [...] María Rodríguez Tates¹, Eddy Alvares Lalvay¹, Luis Chauca Bajaña², Andrea Ordoñez Balladares²

Byron Velásquez Ron ¹, Verónica Mosquera Cisneros¹, [...] Pamela Pazmiño Troncoso¹, María Rodríguez Tates¹, Eddy Alvares Lalvay¹, Luis Chauca Bajaña², Andrea Ordoñez Balladares²

PUBLISHED 05 Dec 2022

Author details Author details

¹ Prosthesis Research, Universidad de Las Américas, Quito, Quito, Pichincha, 170523, Ecuador
² College of Dentistry, Universidad de Guayaquil, Guayas, 090101, Ecuador

Byron Velásquez Ron
Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Verónica Mosquera Cisneros
Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Pamela Pazmiño Troncoso
Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

María Rodríguez Tates
Roles: Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Eddy Alvares Lalvay
Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Luis Chauca Bajaña
Roles: Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Andrea Ordoñez Balladares
Roles: Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

OPEN PEER REVIEW

REVIEWER STATUS

Abstract

Background. Bruxism is a topic of much controversy and is continually debated in the field of dentistry due to the multifaceted clinical relationship that results in painful conditions and consequences to patients. The aim of this review was to determine the effectiveness of a smartphones app in monitoring awake bruxism.
Methods. PROSPERO (registration number: CRD42021271190). The eligibility criteria were as followed: observational studies, case–control studies, studies that reported odds ratios, and studies on awake bruxism. The following keywords were searched: [smartphones apps] AND [apps] AND [awake bruxism], OR [sleep bruxism], OR [sleep hygiene], OR [parasomnias], AND [habits].
Results. All the included studies found that the use of the smartphone app allows controlled awake bruxism monitoring. The results also show that the slepp bruxism and awake bruxism are interactive, having negative synergism and substantially increasing the risks of temporomandibular joint pain and temporomandibular disorders.
Discussion. In the awake bruxims it was possible to identify 70% symptoms through the different frequencies of behavior provided by the App, within the present technological tools have become daily in young and adult population. The app is effective and easy to use by patients, effectively limiting biases the time of evaluation.

Keywords

Awake bruxism; self-report; ecological momentary assessment; smartphone app.

Corresponding author: Byron Velásquez Ron

Competing interests: No competing interests were disclosed.

Grant information: All funds used to support this work were provided by the UDLA (Open 30b36v).
The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright: © 2022 Velásquez Ron B et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to cite: Velásquez Ron B, Mosquera Cisneros V, Pazmiño Troncoso P et al. Monitoring of awake bruxism by intelligent app [version 2; peer review: 2 approved]. F1000Research 2022, 11:479 (https://doi.org/10.12688/f1000research.110673.2) First published: 29 Apr 2022, 11:479 (https://doi.org/10.12688/f1000research.110673.1) Latest published: 05 Dec 2022, 11:479 (https://doi.org/10.12688/f1000research.110673.2)

Revised Amendments from Version 1

The review carried out in the first version of the manuscript, recommends elaborating specific changes in text rather than in form, including references that further clarify the issue is the central point of its recommendations. In the abstract section, writing is improved in results and the abbreviations in the discussion are clarified. In the introduction it is recommended to expand it using more references on the subject, also incorporate literature that justifies the relationship of bruxism with the loss of vertical dimension and temporomandibular disorders, it was also incorporated that bruxism can be considered as a trigger of inflammatory processes in loss of teeth, masticatory pathologies and temporomandibular disorders In table 1 the author Ibriglio is changed by Shopoba, D. et al. 2022 the relevance of the paper is much more attached to the issue of the proposed systematic review, In Table two the titles of the papers are removed, allowing to visualize only the authors with the year of publication, making a better summary in all the sections that does not disperse the interest of the reader as recommended by the reviewers. When correcting the references, all the numbering is relocated, the incorporated works mention bruxism a lot as a public health problem. The corrections made according to the recommendations, improved the initial paper, substantially clarifying the topic, preparing the way for observational research, cross sectional or case control in the short or long term on Awake bruxism.

See the authors' detailed response to the review by Nithin Manchery
See the authors' detailed response to the review by Dobromira Antonova Shopova

Introduction

The controversy when talking about bruxism will always be latent among the academy, from a concept of parafunction to a concept of phenomena wherein biological, psychological and exogenous factors act in greater or lesser percentages.¹ The independent definitions of day bruxism and night bruxism were pointed out at a meeting of different specialties, with oral rehabilitation experts, maxillofacial surgeons and psychologists, who, in 2020, proposed adequate differentiation between the two.² Bruxism is a repetitive jaw muscle activity characterized by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible.³^,⁴ “Bruxism has two distinct circadian manifestations: it can occur during sleep (indicated as sleep bruxism) or during wakefulness (indicated as awake bruxism)”.⁵^,⁶ Treatment of bruxism is reduced to several main methods: increasing the vertical dimension of occlusion (VDO) to normal, mesialization of the jaw to influence the position of the articular condyle in the articular fossa and releasing the disc, and positioning the jaw in a balanced stable occlusion.⁷ This is achieved by splint therapy for a certain period of adaptation and then the result can be fixed by orthodontic treatment, adhesive restorations or prosthetic construction. The stabilizing (occlusal) splint is indicated for the most common symptoms of TMJ and muscle.⁸^,⁹ Awake bruxism is currently defined as “masticatory muscle activity during wakefulness that is characterized by repetitive or sustained dental contact and/or reinforcements or pushes of the jaw and is not a movement disorder in healthy individuals”.¹⁰

Polysomnography (PSG) and electromyography (EMG) have been used for the evaluation of nocturnal bruxism⁷; however for the evaluation of awake bruxism (AB), there was no specific evaluator, until 2018 when an app (Manfredini, Bracci, 2018) was created to evaluate and monitor it through the use of smart devices (smartphones).¹¹ Bruxism is not necessarily considered a pathological behavior, but it has clinical consequences, the frequency of AB in the healthy young population allows us to compare with other groups¹²; in these, psychological factors are determined, including fatigue, muscle pain, tooth wear; having differences between young people and adults differentiating habits and lifestyles that modify the behavior of bruxism.¹³ The cognitive relationship in oral health suggests a bidirectional causal relationship, there is limited evidence that inflammatory mechanisms, tooth loss, masticatory dysfunction, temporo mandibular joint dysfunction and para functions (bruxism) have the potential to contribute to cognitive decline.¹⁴

The use of questionnaires (self-reports), such as clinical observation complemented with electromyography (EMG) have helped in the evaluation of awake bruxism; however, the momentary ecological assessment (EMA) combines real-time approaches to the current state of the patient, which facilitates having an objective assessment.¹⁵ The limitations of non-instrumental methods to assess the AB are high and become subjective, the use of EMA allows to collect data in real time for a certain period of time according to the coding of alerts, which are activated according to the daily life of the individual,¹⁶ the usefulness in the research field is highlighted when evaluating the oral activity of the individual, unfortunately the data obtained are partial, with little research.¹⁷

To limit the bias provided by evaluations of the AB, a group of researchers has introduced an app (BruxApp) for smartphones, its foundation of creation is the implementation of EMA, this collects data through alerts (20 daily) with questions of related conditions simple to accept or deny by the individual: teeth in contact, habits, mandibular hypermobility, clenching and grinding of teeth; characteristic signs of AB.¹⁸ It is taken as a starting point young population (young adults)¹⁹ whom the researchers determine as the control group, it is monitored by the app for a week (20 daily alerts), the frequency was 28.3% in young people with AB with a low coefficient of variation in jaw muscle activity.²⁰ The objective of the present study was to determine the effectiveness of the smartphone app in monitoring awake bruxism. The PICO question was: is the application of smart apps effective in diagnosing daytime bruxism? P: Smartphone patients with the smart app. I: Intervention of all patients with bruxism C: Comparison of bruxism control with the app versus a control group. O: Observation of the percentage of bruxism control.

Methods

This systematic review was registered with PROSPERO under registration number CRD42021271190. The eligibility criteria were as follows: observational studies, case-control studies, studies that reported odds ratios, and studies on awake bruxism. The following keywords were searched using the Boolean operators AND, OR and NOT: [smartphones apps] AND [apps], [awake bruxism], OR [sleep bruxism], OR [sleep hygiene], OR [parasomnias], OR [habits], OR [chewing], OR [teeth grinding], OR [squeezing teeth], OR [parafunctional habits], OR [parafunctional habit], OR [oral habits] OR [oral habit] OR [oral parafunctional] OR [oral parafunctional] OR [oral parafunctional habit] OR [oral parafunctional] OR [oral parafunctional habit] OR [oral parafunctional] OR [parafunctional oral habit] and [Facial pain] OR [temporomandibular joint disorders] OR [Temporomandibular Joint Dysfunction Syndrome] OR [myofascial pain] OR [syndromes] OR [myalgia]] OR [osteoarthritis] OR [pandemic Cov-19] OR [orofacial pain] OR [orofacial pain] OR [TMD] OR [stress] OR [temporomandibular disorder] OR [myofascial pain] OR [disk displacement] OR [young university] OR [young] OR [adult]. The Scopus, EBSCO, PubMed, Medline Embase, Cochrane Library, and Web of Science databases were searched; alternate databases that were searched included Scielo, Latindex, and Redalyc. Using the PRISMA research protocol, the authors used a flowchart to sequentially explain the selected information. The following complete articles published between January 2014 and June 2021 were included: a total of 857 records were obtained; 27 other records were obtained from other sources; 427 duplicate records were deleted; 200 studies were screened; and 102 records were excluded. In total, 98 studies were included in the qualitative analysis, and 16 studies were includedin the quantitative analysis (Figure 1).

Figure 1. Flow diagram research.

The authors (BVVR, VMC, PP, LCHB, EDL) independently reviewed the titles and summaries, excluded duplicates and irrelevant articles, and considered only full-text articles. The dates and names of all authors in the final review article were included. Any conflict with respect to the inclusion and exclusion criteria was resolved by the third and fourth authors (MRT, AOB). To control for bias, the Scala JADAD (Table 1) was used. The data extraction procedure was evaluated according to the criteria of all authors. Articles were classified by the author/year, study objective, study type, methodology, results (standard mean and deviation) and conclusions.

Table 1. Jadad Scale for the evaluation of papers.

Study	Study described as randomized	Study appropriate randomization and well described in the article	Study described as double-blind	Double-blind method appropriate	Double-blind description of errors	Total
Flueraşu, M. et al. 2020.¹³	yes	yes	yes	yes	yes	5
Mir Faeq Ali Quadri, et al. 2015.²³	yes	yes	yes	yes	yes	5
Bracci, et al. 2018.²⁴	yes	yes	yes	yes	yes	5
Reissmann, D. et al. 2017.²⁵	yes	yes	yes	yes	no	4
Machado, N. et al. 2020.²⁶	yes	yes	yes	yes	yes	5
Zani, A. et al. 2019.³¹	yes	yes	yes	yes	yes	5
Shopova, D. et al. 2022.³²	yes	yes	yes	yes	yes	5
Sierwald, I. et al. 2015.³⁶	yes	yes	no	yes	yes	4
Wetsellaar, P. et al. 2021.⁴⁴	yes	yes	yes	yes	yes	5
Wetselaar, P. et al. 2019.⁴⁵	yes	yes	yes	yes	yes	5
Somay, E. et al. 2020.⁴⁶	yes	yes	no	yes	yes	4
Zani, A. et al. 2021.⁴⁷	yes	yes	yes	yes	yes	5
Rofaeel, M. et al. 2021.⁴⁹	yes	no	yes	yes	yes	4
Serra-Negra, J. et al. 2018.⁵⁰	yes	yes	yes	yes	yes	5
Winocur, E. et al. 2019.⁵¹	yes	no	yes	yes	yes	4
Osiewicz, M. et al. 2019.⁵³	yes	yes	yes	yes	yes	5

Results

SB is related to nonfunctional occlusion, while AB is related to occlusal interactions, suggesting the need for a different therapeutic approach (Table 2).

Table 2. Summary review.

Article/Author	Country	Objective/Study Type	Participants	Folow up of period	Results	Conclusion
Mir Faeq Ali Quadri, et al. 2015.²³	Saudi Arabia	To assess prevalence bruxism among university cross-sectional descriptive.	(95%), 85% 63%, men 22%, women	14 days	Association of stress (p = 0.00; OR = 5.902, 95% CI 2.614–13.325) and khat use (p = 0.05; OR = 1.629, 95% CI 0.360–7.368) with bruxism. Experienced 3.56 times (95% CI; 2.62-11.22) less pain compared.	Bruxism with chewing using Khat (Catha edulis).
Wetselaar, P. et al. 2019.⁴⁵	Netherlands	To assess the association of TMD pain with awake and sleep bruxism in adults.	733 patients with TMD 890 patients without TMD	2 months	Patients with TMD (33.9%; p<0.001). Patients with TMD (p<0.001). Awake bruxism (OR 1.7; CI 1.0–2.7) sleep bruxism (OR 1.8; CI 1.4–2.4). Awake and sleepy bruxism (OR 7.7; CI 5.4–11.1).	Negative synergism that substantially increases the risk of TMD pain.
Bracci, A. et al. 2018.²⁴	Italy	Awake bruxism behaviors in a sample of healthy young adults using a smartphone-based app for real time Case Control.	46 dental students 15 alerts 1 week	7 days	Relaxed jaw muscles, during Tooth contact (14.5%) jaw clenching (10.0%) the most frequent awake bruxism behaviors.	Contact between teeth grinding of teeth measured as a function od the percentage o f positive alerts during a 1 week.
Reissmann, D. et al. 2017.²⁵	Germany	To explore whether AB and SB interact in AB and SB interact in their associations with painful temporomandibular disorders (TMD).	705 patients	7 days	Awake bruxism (OR = 6.7; 95% CI 3.4 to 12.9) and sleep (OR = 5.1; 95% CI 3.1 to 8.3). multiplicative interaction OR = 057; 95 % CI 0.24 to 1.4 positive additive interaction RERI = 8.6; 95% CI 1.0 to 19.7.	Awake and sleep bruxism are associated with a greater presence of painful.
Flueraşu, M. et al. 2020.¹³	Rumania	To determine an association between bruxism (sleeping and awake), occlusion (static and dynamic) and pain medications in TMJ in healthy adults Cross-sectional study.	60 subjects 33 women 27 men	1 month	Bruxism than in those without bruxism 3.23 vs 1.46 (p<0.050).	Sleep bruxism is related to non-functional occlusion, while awake bruxism showed occlusal interaction, suggesting the need for a different therapeutic approach.
Machado, N. et al. 2020.²⁶	Brazil	To assess whether the presence of awake bruxism was associated with TMD Cross-sectional study.	56 patients, 58 patients	6 months	The primary effect of awake bruxism was observed when anxiety ANOVA levels of F = 8.61,p = 0.004 and depression ANOVA F = 6.48, p = 0.012 higher and OHRQoL ANOVA F = 8.61, p = 0.04.	Awake bruxism undergoing orthodontic treatment did not develop masticatory muscle.
Wetsellaar, P. et al. 2021.⁴⁴	Netherlands	To assess the prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. Case control	920 subjets	12 months	A prevalence of 4.1% and 4.2% was found for awake bruxism and 7.6% and 13.2% for sleep bruxism.	Sleep bruxism is a common condition in the Dutch adolescent population, while awake bruxism is rarer.
Somay, E. et al. 2020.⁴⁶	Turkey	To assess the prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. Case control	137 patients 68 hemodial 69 healthy individuals. p < 0.05	6 months	Stress (p = 0.00; OR = 5.902, 95% CI 2.614–13.325) khat use (p = 0.05; OR = 1.629, 95% CI 0.360–7.368) with bruxism khat chewer (95% CI 2.62-11.22)	That hemodialysis patients are more sensitive to TMDs sleep bruxism related dental health problems tha healthy individuals.
Shopova, D. et al. 2022.³²	Bulgaria	Complete combined analog and digital clinical protocol in a patient with parafunction.		1 year	The patient was scheduled for periodic monitoring at 3 months. No clinical symptoms of the TMJ were found, the patient also did not report.	Fixed a stable and balanced position of the lower jaw; and repaired the normal physiological position of TMJ.
Rofaeel, M. et al. 2021.⁴⁹	Canada	Measure massage activity and duration intensity of spontaneous episodes of gritting in healthy individuals with different levels of trait anxiety (TA). Case Control	2993 Israeli high school	1 month	Masseter activity high BP groups (10.23 ± 0.16% MVC) TA groups (8.49 0.16% MVC) low (7.97 ± 0.22% MVC) (all p <0,001).p ≥ 0.05). EMG amplitude of tooth clenching episodes high BP groups (19.97 ± 0.21% CVS) <0, 05).></0, 05).> (16.40 ± 0.24% CVS) low (15.48 ± 0.38% MVC) BP groups (all p</0,001).> The cumulative duration of fist-clenching episodes was not different between groups (p = 0.390).	Among adolescents, sleep and wakefulness bruxism are associated with both emotional aspects and symptoms of facial pain and/or alterations of the masticatory system.
Zani, A. et al. 2021.⁴⁷	Italy	Assess the frequency of awake bruxism adopting EMA smarthphone-based technology for one week in a sample. Case control	255 people using axiety disorder (AT) score	6 months	The prevalence of bruxism in the two groups (normal and HFS) was not significantly different (p = 0.37). The rate was not significantly different between sleeping and awake bruxism (p = 0.15) in both groups. Stress influenced the occurrence of bruxism in these two groups (p < 0.001).	The intensity of episodes of awake bruxism increases in individuals with a high trait of anxiety.
Serra-Negra, J. et al. 2018.⁵⁰	Brazil	To assess the association between self-reported awake bruxism (AB) and chronotype profile. Case control	Patients with hemi facial spasms (HFS) for a period of 6 months.	1 week	Awake bruxism 33.7%. chronotype (60.4%), 16.7% had the morning profile. older dental students (OR = 2.640, 95% CI 1.388–5.021) chronotype profile (OR = 3.370, 95% CI 1.302–8.725) with awake bruxism.	The results of this study showed that, although stress has been described as one of the most common aggravating factors in patients with bruxism.
Wetsellaar, P. et al. 2021.⁴⁴	Netherlands	To assess the prevalence of awake bruxism and sleep bruxism. Case Control	One hundred and fifty-three (N = 153) healthy young adults (mean ± age SD = 22.9 ± 3.2 years).	7 days	A prevalence of 5.0% of the total population was found for awake bruxism and 16.5% for sleep bruxism. As for the five age groups, a prevalence of 6.5%, 7.8%, 4.0%, 3.2% and 3.0%, respectively, was found for awake bruxism, EPISODE computer softwear.	Information on the frequency of different awake bruxism behaviors was provided by adopting the EMA approach. Thanks to the use of Smartphone technology. about 23.6% presented awake bruxism behavior and the most frequent condition was “contact with the teeth”, with a percentage of 13.6%.
Winocur, E. et al. 2019.⁵¹	Israel	To determine the emotional, behavioral, and physiological associations of sleep and awakened bruxism among Israeli adolescents. Case Control	255 patients	1 year	(43.4%) bruxism (34.5%) awake bruxism, (14.8%) sleep bruxism, and (7.3%) both sleep and awake bruxism. Odds Ratios (OR) of 1.38, 2.08 and 2.35, respectively). Stress increased the risk of SB by 3.2%, temporomandibular symptoms (OR = 2.17) and chewing difficulties (OR = 2.35). Neck pain showed a negative association (OR = 0.086). anxiety (OR = 1.6).	Anxiety is considered an important trait in patients suffering from awake bruxism. Electromyography is used to measure episodes of spontaneous tooth tightening during wakefulness, it was shown that healthy individuals with a high and clinically relevant anxiety trait have increased mass activity and more intense spontaneous episodes of teeth clenching upon awakening.
Zani, A. et al. 2019.³¹	Italy	Evaluation EMI vs Smarthphone app in Italian young population. Cross Sectional	205 dental students	7 days	T1:62% relaxed jaw muscles 20 % contact with teeth 14% braces awake behaviors T2:74% relaxed jaw muscles 11% contact with teeth 13% braces awake behaviors	Students over the age os 22 and those with the evening chronotype profile were the most likely to suffer from sleep bruxism.
Osiewicz, M. et al. 2019.⁵³	Italy	Describe the process of understanding the BruxApp smartphone application in the context of an ongoing multicenter project on the epidemiology of awakened bruxism (AB). Case Control	Sample of healthy young adults, dental students from 11 universities.	7 days	There are two software versions available, namely BruxApp and BruxApp Research. For both versions, a reverse translation was performed from Polish to English to verify the accuracy of the translation procedure.	Students over the age os 22 and those with the evening chronotype profile were the most likely to suffer from sleep bruxism.

Discussion

All the authors agree that the use of the smartphone app allows controlled AB monitoring by the patient. The current study also showed that the two bruxism are interactive, with negative synergism substantially increasing the risks of TMJ pain and TMD. Signs such as contact between the teeth, clenching of teeth, teeth grinding, and jaw clenching are well defined in the application in AB, it was possible to identify 70% symptoms through the different frequencies of behavior provided by the app, within the present technological tools have become daily in young and adult population.²¹ In the studies reviewed, the EMA was clear for the entire assigned sample.²²^,²³ In the studies that entered the analysis, the six conditions indicated by the application menu were investigated, relaxed jaw muscles (non-contact teeth), teeth in contact (sander in fixed position), mandibular clenching (without contact between the teeth), dental clenching (strong contact in fixed position), dental grinding and area of pain (temporary, interciliary, temple, preauricular, auricular, mandibular angle, mentonian, neck, frontal, infra and supraorbital),²⁴^,²⁵ the data that were obtained were handled by the application menu that allowed to precisely extract a Microsoft Excel file (20 alerts × 7 days) in real time.²⁶ The limitation that was found in the present systematic review is the difficulty of comparing with other studies by the different experimental designs (retrospective), while to apply self-reports are unique times.²⁷ By assessing population behavior frequency is the baseline for observational EMA studies that aids massive data collection,²⁸ it also helps to compare findings related to dietary habits, smoking, medications, psychological pathologies, and comorbid conditions.²⁹ Some studies take as a control group young population Kardeş and Kardeş 2019 analyzed healthy young population finding dental contact (13.6%), teeth grinding (0.5%) and relaxed jaw muscles (76.4%), with a combined frequency of AB of (23.6%).³⁰ Some studies take as a control group young population Bracci et al. 2018 analyzed healthy young population finding dental contact (13.6%), teeth grinding (0.5%) and relaxed jaw muscles (76.4%), with a combined frequency of AB of 23.6%.³¹ These results could be considered a reference point for future research on the epidemiological characteristics of AB in healthy young adults, young people with pathologies, adults and geriatric patients.³²^,³³ The importance of psychological factors was determined, well-defined changes after the COVID-19 pandemic, having been analyzed in AB, the findings were that females are more likely to experience stress, compared with males, the explanation women report better about their emotions³⁴ but the depressive state leads to generate AB crisis with BS in the two genders due to the socio-economic conditions generated by the pandemic, it should be clarified that previous systematic reviews found no gender differences in the frequency of AB³⁵ which contrasts with current information.³⁶ No significant differences were found in the university population, young adults, some authors point out that the monitoring could have been carried out in transition for the student population so that high stress was not indicated, it would be important to develop future research in times such as semester evaluations to determine significant differences.³⁷ It should be considered that the elaboration of the self-report must be controlled, so that unnecessary biases are avoided, for this reason the calibration of the instrument is essential whether individual or group, avoiding or reducing homogeneity to a minimum,³⁸^,³⁹ through training and socialization that allows the population to understand the reliable use of self-report based on EMA.⁴⁰ The characteristics of the populations studied directly influence the results, the age factor, educational level, work activity, socioeconomic status are aspects that influence in substance.⁴¹^,⁴² Camara M, et al. 2020 found that in one week the relaxation of the mandibular muscles was very low, they conclude that not only in healthy young population the symptoms change from one day to the next,⁴³ the population comportment must be specific, this makes variable the behavior of the AB monitored with the app, recognizing natural fluctuation and difficulty in recognizing the symptoms.⁴⁴ Muscle relaxation can be recognized by the individual, also clenching of teeth,⁴⁵ can be a good reference to evaluate the behavior of AB to be a conscious and controlled activity,⁴⁶ other authors indicate that the use of SMEs provides reliability in the monitoring of AB, the reason lowers the influence of natural fluctuation that the population presents regardless of age or gender. It is recommended to conduct future research that considers long-term monitoring of AB, the hypothesis should be tested that the manifestations of AB: relaxed jaw muscles (non-contact teeth), teeth in contact (sander in fixed position), mandibular clenching (no contact between teeth), dental clenching (strong contact in fixed position), dental grinding and area of pain (temporary, interciliary, temple, preauricular, auricular, mandibular angle, mentonian, neck, frontal, infra and supraorbital, clinical consequences such as temporo mandibular joint dysfunction, regional myalgias⁴⁷ are determined. Continuing with the technological line, the effectiveness of an email-based registration and recovery system should be studied if the individual detects non-functional diurnal contact or muscle contracture, an effective strategy for the treatment of temporo mandibular disorders.⁴⁸ An assessment of the associated factors and conditions can, in theory, increase or decrease the frequencies of AB behaviors in the app monitored population based on the EMA self-report (e.g., dietary, or smoking habits, medication use, psychological problems, and comorbid conditions).⁵⁰^,⁵¹ Data can be added to ongoing studies that consider the 2018 definition of bruxism⁵² and the refinement of assessment strategies. Comparisons between populations are necessary and can be used in the context of an ongoing multicenter project on the epidemiology of bruxism.⁵³

Conclusions

The app used to monitor awake bruxism is effective, and its ease of use allows a fundamental approach to diagnosis. It should be noted that the use of the App allows us to monitor the variable behavior of awake bruxism.

Author contributions

Velasquez B: Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Resources, Validation, Visualization, Writing Original Draft Preparation. Writing -review & Edith.

Alvarez E.: Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Resources

Mosquera V: conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Resources

Pazmiño P: conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Resources

Rodriguez M: Conceptualization, Data Curation, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Chauca L: Formal Analysis, Resources, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Ordoñez A: Formal Analysis, Resources, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Data availability

Underlying data

No data are associated with this article.

Acknowledgments

The authors would like to express their special thanks to the UDLA (Universidad de Las Americas).

References

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31. Zani A, Lobbezoo F, Bracci A, et al.: Ecological Momentary Assessment and Intervention Principles for the Study of Awake Bruxism Behaviors, Part 1: General Principles and Preliminary Data on Healthy Young Italian Adults. Front. Neurol. 2019; 10: 169. PubMed Abstract | Publisher Full Text
32. Shopova D, Mladenov K: Case Report: A digital workflow in the treatment of bruxism in a young patient [version 2; peer review: 2 approved]. F1000Research. 2022; 10: 8942. It presents the complete procedure of diagnosis and treatment in case of bruxism only by digital workflow.
33. Manfredini D, Ahlberg J, Aarab G, et al.: Towards a Standardized Tool for the Assessment of Bruxism (STAB)—Overview and general remarks of a multidimensional bruxism evaluation system. J. Oral Rehabil. 2020; 47(5): 549–556. PubMed Abstract | Publisher Full Text
34. Bozhkova T, Shopova D: T-Scan Novus System in the Management of Splints-Pilot Study. Eur. J. Dent. 2022; 16(2): 454–457. PubMed Abstract | Publisher Full Text
35. Ella B, Guillaud E, Langbour N, et al.: Prevalence of Bruxism in Hemifacial-Spasm Patients. J. Prosthodont. 2017; 26(4): 280–283. PubMed Abstract | Publisher Full Text
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39. Shopova D, Yordanova M, Yordanova S: 3Shape Digital Design Software in Splints Creation퉌 – A Pilot Study. Eur. J. Dent. 2021. Here it presents the difference in occlusal surfaces in splints, which every dentist has to know, not to leave the choice in dental technicians.
40. Muzalev K, Visscher CM, Koutris M, et al.: Long-term variability of sleep bruxism and psychological stress in patients with jaw-muscle pain: Report of two longitudinal clinical cases. J. Oral Rehabil. 2018; 45(2): 104–109. PubMed Abstract | Publisher Full Text
41. Manfredini D, Ahlberg J, Winocur E, et al.: Management of sleep bruxism in adults: A qualitative systematic literature review. J. Oral Rehabil. 2015; 42(11): 862–874. PubMed Abstract | Publisher Full Text
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44. Wetselaar P, Vermaire EJH, Lobbezoo F, et al.: The prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. J. Oral Rehabil. 2021; 48(2): 143–149. PubMed Abstract | Publisher Full Text
45. Wetselaar P, Vermaire EJH, Lobbezoo F, et al.: The prevalence of awake bruxism and sleep bruxism in the Dutch adult population. J. Oral Rehabil. 2019; 46: 617–623. PubMed Abstract | Publisher Full Text
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47. Zani A, Lobbezoo F, Bracci A, et al.: Smartphone-based evaluation of awake bruxism behaviours in a sample of healthy young adults: findings from two University centres. J. Oral Rehabil. 2021; 48(9): 989–995. PubMed Abstract | Publisher Full Text
48. Reissmann D, John M, Aigner A, et al.: Interaction Between Awake and Sleep Bruxism Is Associated with Increased Presence of Painful Temporomandibular Disorder. J. Oral Facial Pain Headache. 2017; 31(4): 299–305. PubMed Abstract | Publisher Full Text
49. Rofaeel M, Chow JCF, Cioffi I: The intensity of awake bruxism episodes is increased in individuals with high trait anxiety. Clin. Oral Investig. 2021; 25(5): 3197–3206. PubMed Abstract | Publisher Full Text
50. Serra-Negra JM, Lobbezoo F, Correa-Faria P, et al.: Relationship of self-reported sleep bruxism and awake bruxism with chronotype profiles in Italian dental students. Cranio. 2018; 37(3): 147–152. PubMed Abstract | Publisher Full Text
51. Winocur E, Messer T, Eli I, et al.: Awake and sleep bruxism among Israeli adolescents. Front. Neurol. 2019; 10(10): 443. PubMed Abstract | Publisher Full Text
52. Lobbezo F, Ahlberg J, Raphael K, et al.: International consensus on the assessment of bruxism: Report of a work in progress. J. Oral Rehabil. 2018; 45(11): 837–844. PubMed Abstract | Publisher Full Text
53. Osiewicz M, Lobbezoo F, Bracci A, et al.: Ecological Momentary Assessment and Intervention Principles for the Study of Awake Bruxism Behaviors, Part 2: Development of a Smartphone Application for a Multicenter Investigation and Chronological Translation for the Polish Version. Front. Neurol. 2019; 10(10): 170. eCollection 2019. PubMed Abstract | Publisher Full Text

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Author details Author details

¹ Prosthesis Research, Universidad de Las Américas, Quito, Quito, Pichincha, 170523, Ecuador
² College of Dentistry, Universidad de Guayaquil, Guayas, 090101, Ecuador

Luis Chauca Bajaña
Roles: Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Andrea Ordoñez Balladares
Roles: Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing

Competing interests

No competing interests were disclosed.

Grant information

All funds used to support this work were provided by the UDLA (Open 30b36v).
The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Velásquez Ron B, Mosquera Cisneros V, Pazmiño Troncoso P et al. Monitoring of awake bruxism by intelligent app [version 2; peer review: 2 approved]. F1000Research 2022, 11:479 (https://doi.org/10.12688/f1000research.110673.2)

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Reviewer Report 20 Dec 2022

Dobromira Antonova Shopova, Medical University of Plovdiv, Plovdiv, Bulgaria

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https://doi.org/10.5256/f1000research.140127.r157372

The article is of suitable format, design and content to ... Continue reading

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Reviewer Report 19 Dec 2022

Nithin Manchery, School of Dentistry, The University of Queensland, Brisbane, Qld, Australia

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Reviewer Report 19 Oct 2022

Nithin Manchery, School of Dentistry, The University of Queensland, Brisbane, Qld, Australia

Approved with Reservations

https://doi.org/10.5256/f1000research.122302.r150308

Overall this is an interesting topic of research. A few suggestions for the authors to consider are provided below.

Abstract.

Results section - Suggest rephrasing, " All the authors agree..." to " All

Overall this is an interesting topic of research. A few suggestions for the authors to consider are provided below.

Abstract.

Results section - Suggest rephrasing, " All the authors agree..." to " All the included studies found..."
The sentence " The results also show that...the two bruxism..." is unclear. Please check the sentence.
Kindly define/write the words in full and provide abbreviations within brackets before using them elsewhere in the text (e.g., in the discussion section of the abstract: "AB").

Introduction

Suggest the knowledge gap could be elaborated a little to strongly justify the rationale for this review (e.g. the data are only partial and little research - what were the findings and how did they compare, are there only the 2 studies so far?).
Also, to include the potential implications of the findings from this SR.

Methods

Were articles restricted only to English? Was this limit applied?
In the sentence, "...98 studies were included in the qualitative analysis...", suggest changing to '98 studies were assessed for eligibility...' for better clarity.

Results

Consider explaining the results in detail in word. The basic characteristics, risk of bias, key findings.
Was a meta-analysis considered or avoided due to heterogenicity between the included studies?

Discussion

The authors constantly compare findings between the 2 types of bruxisms. I suppose this deviates from the main aim - which is only focussed on AB.
Are all the limitations addressed? Bias, strength of evidence.

Conclusion

Please add the key findings from the SR and significance of the findings.

Are the rationale for, and objectives of, the Systematic Review clearly stated?

Yes
Are sufficient details of the methods and analysis provided to allow replication by others?

Yes
Is the statistical analysis and its interpretation appropriate?

Yes
Are the conclusions drawn adequately supported by the results presented in the review?

Partly

Competing Interests: No competing interests were disclosed.

Reviewer Expertise: General dentistry and older adults.

I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above.

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Author Response 19 Oct 2022

Byron Velasquez Ron, Prosthesis Research, Universidad de Las Américas, Quito, Quito, 170523, Ecuador

19 Oct 2022

Author Response

Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Competing Interests: No competing interests were disclosed.
Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Competing Interests: No competing interests were disclosed. Close
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Author Response 19 Oct 2022

Byron Velasquez Ron, Prosthesis Research, Universidad de Las Américas, Quito, Quito, 170523, Ecuador

19 Oct 2022

Author Response

Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Competing Interests: No competing interests were disclosed.
Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Thanks so much for your commentaries, in this days working with my team, correct the papers and send with corrections.

Regards.

Byron
Competing Interests: No competing interests were disclosed. Close
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Reviewer Report 30 Sep 2022

Dobromira Antonova Shopova, Medical University of Plovdiv, Plovdiv, Bulgaria

Approved with Reservations

https://doi.org/10.5256/f1000research.122302.r145993

The introduction is short, with only 17 cited authors. In general, the number of references is not large - 50, which tends to the minimum for a review article. I ask the authors to add more articles, especially those published ... Continue reading

Shopova D, Bozhkova T, Yordanova S and Yordanova M. Case Report: Digital analysis of occlusion with T-Scan Novus in occlusal splint treatment for a patient with bruxism [version 2; peer review: 2 approved]. F1000Research 2022, 10:915¹ – It presents a digital device of measurement of occlusal forces, which is very useful in nowadays practice.
Shopova D and Mladenov K. Case Report: A digital workflow in the treatment of bruxism in a young patient [version 2; peer review: 2 approved]. F1000Research 2022, 10:894² – It presents the complete procedure of diagnosis and treatment in case of bruxism only by digital workflow.
Bozhkova, T., & Shopova, D. (2021). T-Scan Novus System in the Management of Splints—Pilot Study. European Journal of Dentistry³. – Again, digital method of measurement of occlusal forces, but with clinical examples.
Shopova, D., Yordanova, M., & Yordanova, S. (2021). Software Details in Occlusal Splint Creation through 3Shape Design Studio. Open Access Macedonian Journal of Medical Sciences, 9(D), 330-335⁴. – The treatment plan is very important. The dentist should know the opportunities of digital software, to know how they can help to the patient in every different situation.
Shopova, D., Bakova, D., Yordanova, M., & Yordanova, S. (2021). TELEDENTISTRY METHODS IN ORTHODONTICS AND PROSTHETIC DENTISTRY DURING COVID-19 PANDEMIC. KNOWLEDGE-International Journal, 49(4), 667-672. – This article presents digital approach of bruxism treatment again, but this time from pandemic point of view.
Shopova, D., Yordanova, M., & Yordanova, S. (2021). 3Shape Digital Design Software in Splints Creation—A Pilot Study. European Journal of Dentistry⁵. – here it presents the difference in occlusal surfaces in splints, which every dentist has to know, not to leave the choice in dental technicians’ hands.
Taneva, I., Grozdanova-Uzunova, R., & Uzunov, T. (2021, March). Occlusal splints–changes in the muscular activity. In Journal of Physics: Conference Series (Vol. 1859, No. 1, p. 012046). IOP Publishing⁶. – The condition of the muscles is very important for the successful result of the treatment in bruxism.
Taneva, I., Uzunov, T., & Milanov, N. (2020). Complete digital approach for bruxism management. Problems of Dental Medicine, 46, 18-27. – It presents modern method of bruxism treatment, very similar with the purpose of the reviewed article.

All of these articles presented the modern methods of diagnosis and treatment in bruxism cases. They can be find in Google scholar or linked to this report, some of them are uploaded in Scopus or Web of Science. Authors can add and more similar articles to enrich their article. 50 cited articles are too small number.

Long tables make the results quite difficult. Try to systematize the cited authors more tightly.

The discussion is voluminous enough and a sufficient number of authors are compared.

The conclusion consists of one short sentence. Authors can submit their opinion on the most suitable app according to them.

Are the rationale for, and objectives of, the Systematic Review clearly stated?

Partly
Are sufficient details of the methods and analysis provided to allow replication by others?

Partly
Is the statistical analysis and its interpretation appropriate?

I cannot comment. A qualified statistician is required.
Are the conclusions drawn adequately supported by the results presented in the review?

No

References

1. Shopova D, Bozhkova T, Yordanova S, Yordanova M: Case Report: Digital analysis of occlusion with T-Scan Novus in occlusal splint treatment for a patient with bruxism. F1000Research. 2022; 10. Publisher Full Text
2. Shopova D, Mladenov K: Case Report: A digital workflow in the treatment of bruxism in a young patient. F1000Research. 2022; 10. Publisher Full Text
3. Bozhkova T, Shopova D: T-Scan Novus System in the Management of Splints-Pilot Study.Eur J Dent. 2022; 16 (2): 454-457 PubMed Abstract | Publisher Full Text
4. Shopova D, Yordanova M, Yordanova S: Software Details in Occlusal Splint Creation through 3Shape Design Studio. Open Access Macedonian Journal of Medical Sciences. 2021; 9 (D): 330-335 Publisher Full Text
5. Shopova D, Yordanova M, Yordanova S: 3Shape Digital Design Software in Splints Creation-A Pilot Study.Eur J Dent. 2021. PubMed Abstract | Publisher Full Text
6. Taneva I, Grozdanova-Uzunova R, Uzunov T: Occlusal splints – changes in the muscular activity. Journal of Physics: Conference Series. 2021; 1859 (1). Publisher Full Text

Competing Interests: No competing interests were disclosed.

Reviewer Expertise: I am a specialist in prosthetic dentistry and in recent years I have been dealing with modern methods for the treatment of bruxism.

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Author Response 03 Oct 2022

Byron Velasquez Ron, Prosthesis Research, Universidad de Las Américas, Quito, Quito, 170523, Ecuador

03 Oct 2022

Author Response

Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Competing Interests: No competing interests were disclosed.
Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Competing Interests: No competing interests were disclosed. Close
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COMMENTS ON THIS REPORT

Author Response 03 Oct 2022

Byron Velasquez Ron, Prosthesis Research, Universidad de Las Américas, Quito, Quito, 170523, Ecuador

03 Oct 2022

Author Response

Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Competing Interests: No competing interests were disclosed.
Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Good morning dear reviewer, we will gladly make the changes as soon as possible from your valuable comments.

Kind regards.
Byron
Competing Interests: No competing interests were disclosed. Close
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Dobromira Antonova Shopova, Medical University of Plovdiv, Plovdiv, Bulgaria
Nithin Manchery, The University of Queensland, Brisbane, Australia

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20 Dec 2022 | for Version 2

Dobromira Antonova Shopova, Medical University of Plovdiv, Plovdiv, Bulgaria

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Approved

The article is of suitable format, design and content to be published in its current form after the corrections made.

Competing Interests

No competing interests were disclosed.

Reviewer Expertise

I am a specialist in prosthetic dentistry and in recent years I have been dealing with modern methods for the treatment of bruxism.

I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.

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19 Dec 2022 | for Version 2

Nithin Manchery, School of Dentistry, The University of Queensland, Brisbane, Qld, Australia

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Approved

The authors have addressed the comments.

Competing Interests

No competing interests were disclosed.

Reviewer Expertise

General dentistry and older adults.

I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.

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19 Oct 2022 | for Version 1

Nithin Manchery, School of Dentistry, The University of Queensland, Brisbane, Qld, Australia

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Approved With Reservations

Overall this is an interesting topic of research. A few suggestions for the authors to consider are provided below.

Abstract.

Results section - Suggest rephrasing, " All the authors agree..." to " All the included studies found..."
The sentence " The results also show that...the two bruxism..." is unclear. Please check the sentence.
Kindly define/write the words in full and provide abbreviations within brackets before using them elsewhere in the text (e.g., in the discussion section of the abstract: "AB").

Introduction

Suggest the knowledge gap could be elaborated a little to strongly justify the rationale for this review (e.g. the data are only partial and little research - what were the findings and how did they compare, are there only the 2 studies so far?).
Also, to include the potential implications of the findings from this SR.

Methods

Were articles restricted only to English? Was this limit applied?
In the sentence, "...98 studies were included in the qualitative analysis...", suggest changing to '98 studies were assessed for eligibility...' for better clarity.

Results

Consider explaining the results in detail in word. The basic characteristics, risk of bias, key findings.
Was a meta-analysis considered or avoided due to heterogenicity between the included studies?

Discussion

The authors constantly compare findings between the 2 types of bruxisms. I suppose this deviates from the main aim - which is only focussed on AB.
Are all the limitations addressed? Bias, strength of evidence.

Conclusion

Please add the key findings from the SR and significance of the findings.

Are the rationale for, and objectives of, the Systematic Review clearly stated?

Yes
Are sufficient details of the methods and analysis provided to allow replication by others?

Yes
Is the statistical analysis and its interpretation appropriate?

Yes
Are the conclusions drawn adequately supported by the results presented in the review?

Partly

Competing Interests

No competing interests were disclosed.

Reviewer Expertise

General dentistry and older adults.

Respond to this report

Responses (1)

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Reviewer Report

14 Views

30 Sep 2022 | for Version 1

Dobromira Antonova Shopova, Medical University of Plovdiv, Plovdiv, Bulgaria

14 Views Cite this report Responses(1)

Approved With Reservations

Shopova D, Bozhkova T, Yordanova S and Yordanova M. Case Report: Digital analysis of occlusion with T-Scan Novus in occlusal splint treatment for a patient with bruxism [version 2; peer review: 2 approved]. F1000Research 2022, 10:915¹ – It presents a digital device of measurement of occlusal forces, which is very useful in nowadays practice.
Shopova D and Mladenov K. Case Report: A digital workflow in the treatment of bruxism in a young patient [version 2; peer review: 2 approved]. F1000Research 2022, 10:894² – It presents the complete procedure of diagnosis and treatment in case of bruxism only by digital workflow.
Bozhkova, T., & Shopova, D. (2021). T-Scan Novus System in the Management of Splints—Pilot Study. European Journal of Dentistry³. – Again, digital method of measurement of occlusal forces, but with clinical examples.
Shopova, D., Yordanova, M., & Yordanova, S. (2021). Software Details in Occlusal Splint Creation through 3Shape Design Studio. Open Access Macedonian Journal of Medical Sciences, 9(D), 330-335⁴. – The treatment plan is very important. The dentist should know the opportunities of digital software, to know how they can help to the patient in every different situation.
Shopova, D., Bakova, D., Yordanova, M., & Yordanova, S. (2021). TELEDENTISTRY METHODS IN ORTHODONTICS AND PROSTHETIC DENTISTRY DURING COVID-19 PANDEMIC. KNOWLEDGE-International Journal, 49(4), 667-672. – This article presents digital approach of bruxism treatment again, but this time from pandemic point of view.
Shopova, D., Yordanova, M., & Yordanova, S. (2021). 3Shape Digital Design Software in Splints Creation—A Pilot Study. European Journal of Dentistry⁵. – here it presents the difference in occlusal surfaces in splints, which every dentist has to know, not to leave the choice in dental technicians’ hands.
Taneva, I., Grozdanova-Uzunova, R., & Uzunov, T. (2021, March). Occlusal splints–changes in the muscular activity. In Journal of Physics: Conference Series (Vol. 1859, No. 1, p. 012046). IOP Publishing⁶. – The condition of the muscles is very important for the successful result of the treatment in bruxism.
Taneva, I., Uzunov, T., & Milanov, N. (2020). Complete digital approach for bruxism management. Problems of Dental Medicine, 46, 18-27. – It presents modern method of bruxism treatment, very similar with the purpose of the reviewed article.

Are the rationale for, and objectives of, the Systematic Review clearly stated?

Partly
Are sufficient details of the methods and analysis provided to allow replication by others?

Partly
Is the statistical analysis and its interpretation appropriate?

I cannot comment. A qualified statistician is required.
Are the conclusions drawn adequately supported by the results presented in the review?

No

References

Competing Interests

No competing interests were disclosed.

Reviewer Expertise

I am a specialist in prosthetic dentistry and in recent years I have been dealing with modern methods for the treatment of bruxism.

Respond to this report

Responses (1)

Alongside their report, reviewers assign a status to the article:

Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested

Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.

Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions

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Monitoring of awake bruxism by intelligent app

Abstract

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