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https://doi.org/10.12688/f1000research.13679.1
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Cutting down the time to identify challenging tumor therapeutic targets and drug combinations using synthetic lethal approaches
[version 1; peer review: 2 approved]
John S. Lazo
Peer Reviewers Kirk McManus; Tero Aittokallio
  • Funders
  • Cure Alzheimer's Fund
  • Fiske Drug Discovery Fund
  • National Institutes of Health
  • Owens Family
  • Department of Defense
PUBLISHED 12 Mar 2018
https://doi.org/10.12688/f1000research.12596.1
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Recent advances in lineage differentiation from stem cells: hurdles and opportunities?
[version 1; peer review: 2 approved]
Joke Terryn, Tine Tricot, Madhavsai Gajjar, Catherine Verfaillie
Peer Reviewers Amander T Clark; Gareth J Sullivan
  • Funder
  • Agency for Innovation by Science and Technology
PUBLISHED 23 Feb 2018
https://doi.org/10.12688/f1000research.13115.1
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Recent advances in understanding evolution of the placenta: insights from transcriptomics
[version 1; peer review: 4 approved]
Anthony M. Carter
Peer Reviewers Oliver W Griffith; Marilyn Renfree; Derek E. Wildman; Cornelis Guillaume
PUBLISHED 19 Jan 2018
https://doi.org/10.12688/f1000research.12679.1
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Molecular mechanisms of macrophage Toll-like receptor–Fc receptor synergy
[version 1; peer review: 2 approved]
Michelle Lennartz, James Drake
Peer Reviewers Aleksandra Nita-Lazar; Ashley Mansell
  • Funders
  • Albany Medical College - Bridge Grant Program
  • Johnathan Vasiliou Foundation
  • National Institutes of Health
PUBLISHED 08 Jan 2018
https://doi.org/10.12688/f1000research.11491.1
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The emerging landscape of in vitro and in vivo epigenetic allelic effects
[version 1; peer review: 2 approved]
Christopher Gregg
Peer Reviewers Catherine Dulac; Rebecca Oakey
  • Funders
  • New York Stem Cell Foundation
  • Simons Foundation Autism Research Initiative
  • National Institute of Mental Health Research
PUBLISHED 07 Dec 2017
https://doi.org/10.12688/f1000research.12138.1
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Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum
[version 1; peer review: 3 approved]
Alexander McQuiston, J Alan Diehl
Peer Reviewers Eric Chevet; Linda Hendershot; David Wiest
  • Funder
  • National Institutes of Health
PUBLISHED 27 Oct 2017
https://doi.org/10.12688/f1000research.11581.1
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Recent advances in high-throughput approaches to dissect enhancer function
[version 1; peer review: 3 approved]
David Santiago-Algarra, Lan T.M. Dao, Lydie Pradel, Alexandre España, Salvatore Spicuglia
Peer Reviewers Alvaro Rada-Iglesias; Douglas Vernimmen; Bart Deplancke
  • Funders
  • ARC
  • CONACYT-Mexico
  • Vietnam International Education Development
  • Plan Cancer
PUBLISHED 19 Jun 2017
https://doi.org/10.12688/f1000research.11113.1
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Genetic and epigenetic control of gene expression by CRISPR–Cas systems
[version 1; peer review: 3 approved]
Albert Lo, Lei Qi
Peer Reviewers Luciano Marraffini; Charles Gersbach; Rodolphe Barrangou
  • Funders
  • NIH Office of the Director
  • The Pew Charitable Trusts
  • Alfred P. Sloan Foundation
PUBLISHED 25 May 2017
https://doi.org/10.12688/f1000research.11034.1
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Wnt target genes and where to find them
[version 1; peer review: 3 approved]
Aravinda-Bharathi Ramakrishnan, Ken M. Cadigan
Peer Reviewers Hans Clevers; Stefan Hoppler; Randall Moon
  • Funder
  • National Institutes of Health
PUBLISHED 24 May 2017
https://doi.org/10.12688/f1000research.10152.1
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Mechanisms of pathogenesis of emerging adenoviruses
[version 1; peer review: 2 approved]
James Cook, Jay Radke
Peer Reviewers David Ornelles; Hans-Gerhard Burgert
PUBLISHED 30 Jan 2017
https://doi.org/10.12688/f1000research.10079.1
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Fact or fiction: updates on how protein-coding genes might emerge de novo from previously non-coding DNA
[version 1; peer review: 3 approved]
Jonathan F Schmitz, Erich Bornberg-Bauer
Peer Reviewers Chuan-Yun Li; Tomislav Domazet-Lošo; M Mar Albà
PUBLISHED 19 Jan 2017
https://doi.org/10.12688/f1000research.9404.1
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Protein-mRNA interactome capture: cartography of the mRNP landscape
[version 1; peer review: 3 approved]
Sean P. Ryder
Peer Reviewers Traci Hall; Jeff Chao; Anita Corbett
PUBLISHED 03 Nov 2016
https://doi.org/10.12688/f1000research.9241.1
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Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome
[version 1; peer review: 4 approved]
Pedro Morgado, Dipak Manna, Upinder Singh
Peer Reviewers Lesly Temesvari; Sudha Bhattacharya; Sharon Reed; Tomoyoshi Nozaki
PUBLISHED 26 Oct 2016
https://doi.org/10.12688/f1000research.9218.1
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Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance
[version 1; peer review: 5 approved]
Marie-Claude N. Laffitte, Philippe Leprohon, Barbara Papadopoulou, Marc Ouellette
Peer Reviewers Francisco Gamarro; Joachim Clos; Richard McCulloch; Yvon Sterkers; Gerald Spaeth
PUBLISHED 20 Sep 2016
https://doi.org/10.12688/f1000research.9180.1
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Circadian influences on dopamine circuits of the brain: regulation of striatal rhythms of clock gene expression and implications for psychopathology and disease
[version 1; peer review: 2 approved]
Michael Verwey, Sabine Dhir, Shimon Amir
Peer Reviewers Christopher S. Colwell; Diego Golombek
PUBLISHED 24 Aug 2016
https://doi.org/10.12688/f1000research.7913.1
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Linking Α to Ω: diverse and dynamic RNA-based mechanisms to regulate gene expression by 5′-to-3′ communication
[version 1; peer review: 2 approved]
Megan E. Filbin, Jeffrey S. Kieft
Peer Reviewers W. Allen Miller; Katherine Fitzgerald
PUBLISHED 19 Aug 2016
https://doi.org/10.12688/f1000research.8818.1
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Mapping paths: new approaches to dissect eukaryotic signaling circuitry
[version 1; peer review: 3 approved]
Nebibe Mutlu, Anuj Kumar
Peer Reviewers Todd Reynolds; Paul J. Cullen; Heng Zhu
PUBLISHED 27 Jul 2016
https://doi.org/10.12688/f1000research.8349.1
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Long noncoding RNAs in hematopoiesis
[version 1; peer review: 2 approved]
Xu Zhang, Wenqian Hu
Peer Reviewers Vinod Scaria; Chris P. Ponting
PUBLISHED 20 Jul 2016
https://doi.org/10.12688/f1000research.8601.1
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Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?
[version 1; peer review: 2 approved]
Sabine Müller, Bettina Appel, Darko Balke, Robert Hieronymus, Claudia Nübel
Peer Reviewers Jörg Hartig; Marcel Hollenstein
PUBLISHED 27 Jun 2016
https://doi.org/10.12688/f1000research.8455.1
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Recent advances in understanding transcription termination by RNA polymerase II
[version 1; peer review: 2 approved]
Travis J. Loya, Daniel Reines
Peer Reviewers David Brow; Dong Wang
PUBLISHED 23 Jun 2016
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