<p>Next-generation sequencing of human tumor xenografts is significantly improved by prior depletion of mouse cell</p>

Stefan Tomiuk; David Agorku; Kerstin Klingner; Stefan Wild; Silvia Rüberg; Lisa Zatrieb; Andreas Bosio; Julia Schueler; Olaf Hardt

doi:10.7490/f1000research.1110286.1

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Tomiuk S, Agorku D, Klingner K et al. Next-generation sequencing of human tumor xenografts is significantly improved by prior depletion of mouse cell [version 1; not peer reviewed]. F1000Research 2015, 4(ISCB Comm J):537 (poster) (https://doi.org/10.7490/f1000research.1110286.1)

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Next-generation sequencing of human tumor xenografts is significantly improved by prior depletion of mouse cell

Stefan Tomiuk¹, David Agorku, Kerstin Klingner, Stefan Wild, Silvia Rüberg, Lisa Zatrieb, Andreas Bosio, Julia Schueler, Olaf Hardt¹

Published 10 Aug 2015 (https://doi.org/10.7490/f1000research.1110286.1)

Author Affiliations

¹ Miltenyi Biotec GmbH, Germany

Copyright © 2015 Tomiuk S et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CITE

Published 10 Aug 2015

Next-generation sequencing of human tumor xenografts is significantly improved by prior depletion of mouse cell
[version 1; not peer reviewed]

Stefan Tomiuk¹, David Agorku, Kerstin Klingner, Stefan Wild, Silvia Rüberg, Lisa Zatrieb, Andreas Bosio, Julia Schueler, Olaf Hardt¹

Author Affiliations

¹ Miltenyi Biotec GmbH, Germany

Presented at

23rd Annual International Conference on Intelligent Systems for Molecular Biology and the 14th European Conference on Computational Biology 2015

American Association for Cancer Research Annual Meeting 2015

Abstract

Competing Interests

No competing interests were disclosed

Keywords

next generation sequencing, NGS, SNP, SNV, tumor, xenograft, cancer, exome sequencing, WES, mouse cell depletion

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