YCharOS (Antibody Characterization through Open Science)
YCharOS (Antibody Characterization through Open Science)
Parkinson's disease (PD)
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AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for DJ-1 (PARK7) (Q99497) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- Michael J. Fox Foundation for Parkinson's Research
- This work was supported by the Michael J. Fox Foundation for Parkinson’s Research (MJFF) (grant no. 18331). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
- Québec Consortium for Drug Discovery
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AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for TMEM175 (UniProt ID: Q9BSA9) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- This research was partly funded by the G-Can (GBA1-Canada) initiative, an open-science collaboration dedicated to advancing research on Parkinson's disease associated with GBA1 mutations. G-Can is supported by The Hilary & Galen Weston Foundation, Silverstein Foundation, and J. Sebastian van Berkom and Ghislaine Saucier. This work was also supported by the CQDM (by a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec) and by the Government of Canada through Genome Canada, Genome Quebec, and Ontario Genomics (grant no. OGI-210).
- Genome Canada
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A guide to selecting high-performing antibodies for SCARB2 (UniProt ID: Q14108) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 1 approved with reservations]
Peer Reviewers
Jieya Shao
- Funders
- Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec
- The Hilary & Galen Weston Foundation, Silverstein Foundation, and J. Sebastian van Berkom and Ghislaine Saucier
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for ASM (UniProt ID: P17405) for use in western blot and immunoprecipitation
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- G-Can (GBA1-Canada) initiative
- CQDM (by a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec)
Data Note
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Revised
A guide to selecting high-performing antibodies for Stearoyl-CoA desaturase (SCD1) (UniProt ID: O00767) for use in western blot, immunoprecipitation, and immunofluorescence
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Cecilia Williams and Matilda Holm;
Michael L. Garelja;
Deborah Moshinsky
- Funders
- Ontario Genomics
- Michael J. Fox Foundation for Parkinson's Research
- Génome Québec
- Mitacs
- Genome Canada
Data Note
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Revised
A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence
[version 2; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers
Karen Bowman;
Jieya Shao;
Sheng-ce Tao;
Mathias Nielsen and John LaCava
- Funders
- Ontario Genomics
- Michael J. Fox Foundation for Parkinson’s Disease Research
- Genome Quebec
- Mitacs
- Genome Canada
Data Note
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A guide to selecting high-performing antibodies for CSNK1A1 (UniProt ID: P48729) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Jan Voskuil
- Funders
- Ontario Genomics
- Micas
- Genome Quebec
- Genome Canada
- Michael J. Fox Foundation for Parkinson’s Research
Data Note
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Revised
A guide to selecting high-performing antibodies for Protein-glutamine gamma-glutamyltransferase 2 (TGM2) for use in western blot, immunoprecipitation and immunofluorescence
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Michael A Rieger;
Nicoletta Bianchi;
Steve Jean
- Funders
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- Michael J. Fox Foundation for Parkinson's Research
- Genome Quebec
- Mitacs
- Genome Canada
Data Note
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Revised
Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
[version 2; peer review: 2 approved]
Peer Reviewers
Maria-Paz Marzolo and Vania Macias;
Emily Sontag
- Funders
- Ontario Genomics
- Mitacs
- Genome Quebec
- Genome Canada
- Michael J. Fox Foundation for Parkinson’s Research
Data Note
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The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Dawn Smallwood;
Christian Peter Moritz;
Giuseppe Legname
- Funders
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- ALS Canada
- ALS Association
- Motor Neurone Disease Association
- Genome Quebec
- Mitacs
- Genome Canada