YCharOS (Antibody Characterization through Open Science)
YCharOS (Antibody Characterization through Open Science)
Featured Article
Editorial
metrics
NOT PEER REVIEWED
YCharOS open antibody characterisation data: Lessons learned and progress made
[version 1; peer review: not peer reviewed]
- Funders
- Medical Research Council
- Leicester Institute of Advanced Studies
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing renewable antibodies for KIF5A (Q12840) across western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- Structural Genomics Consortium
- Thank you to the Structural Genomics Consortium, a registered charity (no. 1097737), for your support on this project. The Structural Genomics Consortium receives funding from Bayer AG, Boehringer Ingelheim, Bristol-Myers Squibb, Genentech, Genome Canada through Ontario Genomics Institute (grant no. OGI196), the EU and EFPIA through the Innovative Medicines Initiative 2 Joint Undertaking (EUbOPEN grant no. 875510), Janssen, Merck KGaA (also known as EMD in Canada and the United States), Pfizer and Takeda.
- Genome Canada
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for Syntenin-1 (O00560) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- This work was supported in part by the Emory-Sage-SGC TaRget Enablement to Accelerate Therapy Development for Alzheimer’s Disease (TREAT-AD) center established by the National Institute on Aging (grant no. U54AG065187). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
- Michael J. Fox Foundation for Parkinson's Research
- TREAT-AD
- Québec Consortium for Drug Discovery
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for DJ-1 (PARK7) (Q99497) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- Michael J. Fox Foundation for Parkinson's Research
- This work was supported by the Michael J. Fox Foundation for Parkinson’s Research (MJFF) (grant no. 18331). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
- Québec Consortium for Drug Discovery
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for TMEM175 (UniProt ID: Q9BSA9) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- This research was partly funded by the G-Can (GBA1-Canada) initiative, an open-science collaboration dedicated to advancing research on Parkinson's disease associated with GBA1 mutations. G-Can is supported by The Hilary & Galen Weston Foundation, Silverstein Foundation, and J. Sebastian van Berkom and Ghislaine Saucier. This work was also supported by the CQDM (by a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec) and by the Government of Canada through Genome Canada, Genome Quebec, and Ontario Genomics (grant no. OGI-210).
- Genome Canada
Data Note
metrics
A guide to selecting high-performing antibodies for SCARB2 (UniProt ID: Q14108) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Jieya Shao;
Deborah Moshinsky
- Funders
- Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec
- The Hilary & Galen Weston Foundation, Silverstein Foundation, and J. Sebastian van Berkom and Ghislaine Saucier
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for ASM (UniProt ID: P17405) for use in western blot and immunoprecipitation
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funders
- G-Can (GBA1-Canada) initiative
- CQDM (by a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec)
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for ARID1B (UniProt ID: Q8NFD5) for use in western blot and immunoprecipitation
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funder
- This work was supported by the Terry Fox Foundation for Cancer Research (grant no. 1190-09). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Data Note
metrics
AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for ARID1A (UniProt ID: O14497) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funder
- This work was supported by the Terry Fox Foundation for Cancer Research (grant no. 1190-09). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Data Note
metrics
A guide to selecting high-performing antibodies for ARID2 (UniProt ID: Q68CP9) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Karen Bowman;
Deborah Moshinsky
- Funder
- This work was supported by the Terry Fox Foundation for Cancer Research (grant no. 1190-09). This work was also supported by a grant from the Quebec Consortium for Drug Discovery (CQDM), a grant from the Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Data Note
metrics
A guide to selecting high-performing antibodies for MMP7 (UniProt ID: P09237) for use in western blot and immunoprecipitation
[version 1; peer review: 2 approved]
Peer Reviewers
Jieya Shao;
Christian Tiede
- Funders
- Medical Research Council
- National Centre for the Replacement Refinement and Reduction of Animals in Research
Data Note
metrics
A guide to selecting high-performing antibodies for Alpha-1-antitrypsin (UniProt ID: P01009) for use in western blot, immunoprecipitation and flow cytometry
[version 1; peer review: 2 approved]
Peer Reviewers
Steve Jean;
Sian E. Evans
- Funders
- National Centre for the Replacement, Refinement and Reduction of Animals in Research
- Medical Research Council
Data Note
metrics
A guide to selecting high-performing antibodies for GCase (UniProt ID: P04062) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Karen Bowman
- Funders
- Ministère de l’Économie, de l’Innovation et de l’Énergie du Québec
- The Hilary & Galen Weston Foundation, Silverstein Foundation, and J. Sebastian van Berkom and Ghislaine Saucier
Data Note
metrics
A guide to selecting high-performing antibodies for Heterogeneous nuclear ribonucleoproteins A2/B1(hnRNP A2/B1) (UniProt ID: P22626) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Sian E. Evans
- Funder
- ALS-Reproducible Antibody Platform (ALS-RAP)
Data Note
metrics
A guide to selecting high-performing antibodies for Optineurin (UniProt ID: Q96CV9) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Andrew Buchanan
- Funders
- ALS Society of Canada
- ALS Association
- Motor Neurone Disease Association
- Québec Consortium for Drug Discovery
Data Note
metrics
A guide to selecting high-performing antibodies for VCP (UniProt ID: P55072) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Karen Bowman
- Funders
- ALS Society of Canada
- ALS Association
- Motor Neurone Disease Association
- Mitacs
- Québec Consortium for Drug Discovery
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for Stearoyl-CoA desaturase (SCD1) (UniProt ID: O00767) for use in western blot, immunoprecipitation, and immunofluorescence
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Cecilia Williams and Matilda Holm;
Michael L. Garelja;
Deborah Moshinsky
- Funders
- Ontario Genomics
- Michael J. Fox Foundation for Parkinson's Research
- Génome Québec
- Mitacs
- Genome Canada
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence
[version 3; peer review: 2 approved]
Peer Reviewers
Shinsuke Niwa;
Claudia Fallini
- Funders
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- Mitacs
- Genome Québec
- Genome Canada
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for S1PR1 (UniProt ID: P21453) for use in western blot, immunoprecipitation, and immunofluorescence
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Melissa Pitman;
Christian Tiede;
Jieya Shao
- Funders
- Ontario Genomics
- Mitacs
- Genome Quebec
- Emory-Sage-SGC TaRget Enablement to Accelerate Therapy Development for Alzheimer’s Disease
- Genome Canada
- National Institute on Aging
Data Note
metrics
A guide to selecting high-performing antibodies for TAF15 (UniProt ID: Q92804) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: 2 approved]
Peer Reviewers
Deborah Moshinsky;
Sian E. Evans and Carolyn Jones
- Funders
- Ontario Genomics
- ALS Society of Canada
- Génome Québec
- ALS Association
- Motor Neurone Disease Association
- Mitacs
- Genome Canada
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence
[version 2; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers
Karen Bowman;
Jieya Shao;
Sheng-ce Tao;
Mathias Nielsen and John LaCava
- Funders
- Ontario Genomics
- Michael J. Fox Foundation for Parkinson’s Disease Research
- Genome Quebec
- Mitacs
- Genome Canada