All Research Articles

1-20 of 638 ARTICLES
https://doi.org/10.12688/f1000research.172236.2
Research Article metrics
Revised
Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid Leukemia
[version 2; peer review: 2 approved with reservations]
Peer Reviewers Ikhwan Rinaldi; haijiao Zhang and Anna He
LATEST VERSION PUBLISHED 05 Feb 2026
https://doi.org/10.12688/f1000research.175540.1
Software Tool Article metrics AWAITING PEER REVIEW
Workflow graphical editor and translator to Nextflow
[version 1; peer review: awaiting peer review]
Peer Reviewers Invited
  • Funder
  • «Sirius» Federal Territory
PUBLISHED 29 Jan 2026
https://doi.org/10.12688/f1000research.175162.1
Software Tool Article metrics AWAITING PEER REVIEW
Spotsweeper-py: spatially-aware quality control metrics for spatial omics data in the Python ecosystem
[version 1; peer review: awaiting peer review]
Peer Reviewers Invited
  • Funders
  • National Institute of Mental Health
  • National Institute of General Medical Sciences
PUBLISHED 09 Jan 2026
https://doi.org/10.12688/f1000research.168786.2
Software Tool Article metrics
Revised
Identification of Viral Variants from Functional Genomics Data
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Dóra Tombácz; Anuj Kumar
  • Funder
  • Deutsche Forschungsgemeinschaft
LATEST VERSION PUBLISHED 31 Dec 2025
https://doi.org/10.12688/f1000research.173116.1
Opinion Article metrics
Strengthening bioinformatics education: e-learning initiatives across ELIXIR Nodes and Communities
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Michelle D. Brazas; Ming Chen; Gangqing Hu
PUBLISHED 22 Dec 2025
https://doi.org/10.12688/f1000research.171697.1
Research Article metrics
Antibiogram, antibiotic resistance genes and health risks of Listeria species from fruits and vegetables in selected locations in Nigeria
[version 1; peer review: 1 approved]
Peer Reviewers Rahul Vashishth
  • Funder
  • National Research Foundation
PUBLISHED 22 Dec 2025
https://doi.org/10.12688/f1000research.124810.2
Software Tool Article metrics
Revised
abmAnimalMovement: An R package for simulating animal movement using an agent-based model
[version 2; peer review: 4 approved with reservations]
Peer Reviewers Rocío Joo; Andrea Contina; Pratik Rajan Gupte; Luciano Bosso
  • Funder
  • Natural Environment Research Council
LATEST VERSION PUBLISHED 17 Dec 2025
https://doi.org/10.12688/f1000research.172407.1
Research Article metrics
Bioinformatics-based Investigation to Unveiling The miRNA-Immunity Axis in The Tumor Microenvironment of Pancreatic Cancer
[version 1; peer review: 1 approved with reservations]
Peer Reviewers Fadehl Lafta
  • Funder
  • The authors received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.
PUBLISHED 16 Dec 2025
https://doi.org/10.12688/f1000research.164583.2
Software Tool Article metrics
Revised
Assembly and quantification of transcripts from noisy long reads with NIFFLR
[version 2; peer review: 1 approved with reservations, 2 not approved]
Peer Reviewers Colin Dewey; Fairlie Reese; Yuan Gao
  • Funders
  • Directorate for Biological Sciences
  • NIH
LATEST VERSION PUBLISHED 03 Dec 2025
https://doi.org/10.12688/f1000research.171889.1
Software Tool Article metrics
BISCUIT: An Open-Source Platform for Visual Comparison of Segmentation Models in Bioimage Analysis
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Constantin Pape Pape; Peter Bankhead and Laura Nicolás-Sáenz
PUBLISHED 18 Nov 2025
https://doi.org/10.12688/f1000research.166538.2
Review metrics
Revised
White paper: standards for handling and analyzing plant pan-genomes
[version 2; peer review: 2 approved, 2 approved with reservations]
Peer Reviewers Sunil Kumar Sahu; Xiaoming Xie; Rutwik Barmukh; Jianping Xu
  • Funders
  • ELIXIR under the call for proposals on Biodiversity, Food Safety and Pathogens
  • Federal Ministry of Education and Research
LATEST VERSION PUBLISHED 18 Nov 2025
https://doi.org/10.12688/f1000research.170665.1
Software Tool Article metrics
Sixth Annual BCM Hackathon on Structural Variation and Pangenomics
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Istvan Albert; Colin Diesh
  • Funders
  • Shwetha V Kumar is supported by CPRIT grant #RP210037 (PI Aaron Thrift)
  • Ryan Doughty is supported by a training fellowship from the Gulf Coast Consortia, on the NLM Training Program in Biomedical Informatics & Data Science (T15LM007093)
  • Sarah Fross is supported by a training grant from the National Institutes of Health under Award Number 5T32GM135748-04.
  • Sedlazeck NIH grant: 1UG3NS132105-01, 1U01HG011758-01
  • Jędrzej Kubica is supported by the Ministry of Science and Higher Education (Poland) as a project under the program Excellence Initiative – Research University (2020–2026) (decision no.: IV.2.3./30/2024) and the France 2030 state funding managed by the National Research Agency with the reference
  • Shaghayegh Beheshti is supported by a training grant from the National Institutes of Health under Award Number 5T32GM139534-04 and NHGRI U01 HG011758.
  • The research was supported by Cancer Prevention and Research Institute of Texas under grant number: #RP210037
PUBLISHED 07 Nov 2025
https://doi.org/10.12688/f1000research.166678.2
Research Article metrics
Revised
Exploring the Potential of Peptides Derived from the Coelomic Fluid of Echinometra lucunter Targeting Inflammatory Cytokines in Placental Syndromes: In Silico Study
[version 2; peer review: 2 approved]
Peer Reviewers Aldi Tamara Rahman; Norbertus Marcell Prayogi
LATEST VERSION PUBLISHED 06 Nov 2025
https://doi.org/10.12688/f1000research.171468.1
Software Tool Article metrics
DTAShiny: An Interactive R Shiny Application for Diagnostic Test Accuracy Analysis and Visualization
[version 1; peer review: 3 approved with reservations]
Peer Reviewers Christos Nakas; Budi Sunaryo; Pedro Castaneda
PUBLISHED 30 Oct 2025
https://doi.org/10.12688/f1000research.162353.2
Research Article metrics
Revised
Optimizing Cardiovascular Treatment in Non-Small Cell Lung Cancer: A Comprehensive Computational Approach for Assessment of Drug-Drug Interactions Between Tyrosine Kinase Inhibitors and Cardiovascular Drugs
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Fahrul Nurkolis; Uday Venkat Mateti; Janmejay Pant
LATEST VERSION PUBLISHED 22 Oct 2025
https://doi.org/10.12688/f1000research.170810.1
Software Tool Article metrics AWAITING PEER REVIEW
DirectRepeateR: An R package for annotating direct repeats in genome assemblies
[version 1; peer review: awaiting peer review]
Peer Reviewers Invited
  • Funders
  • National Institute of Allergies and Infectious Diseases, National Institutes of Health
  • National Institute of General Medical Sciences at the National Institutes of Health
PUBLISHED 21 Oct 2025
https://doi.org/10.12688/f1000research.171282.1
Research Article metrics
’Spanscriptomics’: towards bioinformatics training materials in Spanish.
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Carlos C. Goller; Wei Ruan
  • Funder
  • Company of Biologists
PUBLISHED 20 Oct 2025
https://doi.org/10.12688/f1000research.129581.2
Software Tool Article metrics
Revised
AmpSeqR: an R package for amplicon deep sequencing data analysis
[version 2; peer review: 3 approved]
Peer Reviewers Eduardo Castro-Nallar; Cristian Koepfli and Gustavo Da Silva; Patrick Murigu Kamau Njage
  • Funders
  • Institute Infrastructure Support Scheme (IRIISS)
  • National Health and Medical Research Council
LATEST VERSION PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.164530.1
Research Article metrics AWAITING PEER REVIEW
Inferring and simulating a gene regulatory network for the sympathoadrenal differentiation from single-cell transcriptomics in human.
[version 1; peer review: awaiting peer review]
Peer Reviewers Invited
  • Funder
  • Ligue Contre le Cancer
PUBLISHED 11 Sep 2025
https://doi.org/10.12688/f1000research.169977.1
Editorial metrics NOT PEER REVIEWED
BOSC 2025, the 26th Bioinformatics Open Source Conference
[version 1; peer review: not peer reviewed]
  • Funder
  • NA
PUBLISHED 09 Sep 2025
1-20 of 638 ARTICLES
Articles
We publish a wide range of article types in science, engineering, medicine, social sciences and humanities, with no editorial biases.
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