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https://doi.org/10.12688/f1000research.26928.1
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Control of T lymphocyte fate decisions by PI3K signaling
[version 1; peer review: 2 approved]
Benjamin Murter, Lawrence P. Kane
Peer Reviewers Pam Schwartzberg; Klaus Okkenhaug
  • Funder
  • National Institutes of Health
PUBLISHED 25 Sep 2020
https://doi.org/10.12688/f1000research.22092.1
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An overview of mammalian p38 mitogen-activated protein kinases, central regulators of cell stress and receptor signaling
[version 1; peer review: 2 approved]
Jiahuai Han, Jianfeng Wu, John Silke
Peer Reviewers Jonathan D. Ashwell; Guadalupe Sabio
  • Funders
  • The 111 Project
  • National Natural Science Foundation of China
  • National Health and Medical Research Council
PUBLISHED 29 Jun 2020
https://doi.org/10.12688/f1000research.22367.1
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Coordination of Rheb lysosomal membrane interactions with mTORC1 activation
[version 1; peer review: 4 approved]
Brittany Angarola, Shawn M. Ferguson
Peer Reviewers Rolf Heumann; David M Sabatini and Justin Roberts; Robbie Loewith; Roberto Zoncu
  • Funder
  • National Institutes of Health
PUBLISHED 27 May 2020
https://doi.org/10.12688/f1000research.20942.1
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Desmosomes:  Essential contributors to an integrated intercellular junction network
[version 1; peer review: 2 approved]
Kathleen J Green, Avinash Jaiganesh, Joshua A Broussard
Peer Reviewers Alexa Mattheyses; Thomas Magin
  • Funders
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • American Heart Association
  • Joseph L. Mayberry Endowment
  • National Cancer Institute
PUBLISHED 30 Dec 2019
https://doi.org/10.12688/f1000research.20094.1
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What do archaeal and eukaryotic histidine kinases sense?
[version 1; peer review: 3 approved]
Nicolas Papon, Ann M. Stock
Peer Reviewers Wei Qian; Jeffrey J. Tabor; Sean Crosson
  • Funder
  • National Institutes of Health
PUBLISHED 27 Dec 2019
https://doi.org/10.12688/f1000research.20013.1
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Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment
[version 1; peer review: 2 approved]
Lukas Tamayo-Orrego, Frédéric Charron
Peer Reviewers Timothy R Gershon; James Manfredi
  • Funders
  • Canada Foundation for Innovation
  • Canadian Institutes of Health Research
PUBLISHED 29 Oct 2019
https://doi.org/10.12688/f1000research.18872.1
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Emerging approaches to target mitochondrial apoptosis in cancer cells
[version 1; peer review: 3 approved]
Andrew Gilmore, Louise King
Peer Reviewers Peter Czabotar; Stephen Tait; Natasha Kyprianou
  • Funders
  • Cancer Research UK
  • Wellcome Trust
PUBLISHED 24 Oct 2019
https://doi.org/10.12688/f1000research.20003.1
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Autoactivation of small GTPases by the GEF–effector positive feedback modules
[version 1; peer review: 2 approved]
Andrew B. Goryachev, Marcin Leda
Peer Reviewers Laura M. Machesky; Catherine L. Jackson
  • Funder
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 23 Sep 2019
https://doi.org/10.12688/f1000research.19139.1
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Mitochondrial dysregulation and muscle disuse atrophy
[version 1; peer review: 2 approved]
Li Li Ji, Dongwook Yeo
Peer Reviewers David A. Hood; Roberto Bottinelli
  • Funder
  • University of Minnesota Twin Cities
PUBLISHED 11 Sep 2019
https://doi.org/10.12688/f1000research.16701.1
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Molecular regulation of arteriovenous endothelial cell specification
[version 1; peer review: 2 approved]
Jennifer S. Fang, Karen K. Hirschi
Peer Reviewers Ondine Cleaver; Helen Arthur
  • Funders
  • CT Innovations
  • National Institutes of Health
PUBLISHED 29 Jul 2019
https://doi.org/10.12688/f1000research.16160.1
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Genetic investigation of childhood vascular tumor biology reveals pathways for therapeutic intervention
[version 1; peer review: 2 approved]
Shayan Cheraghlou, Young Lim, Keith Choate
Peer Reviewers Joyce Bischoff; Douglas A. Marchuck
  • Funders
  • Leon Rosenberg, M.D., Medical Student Research Fund in Genetics
  • Jane Danowski Weiss Family Foundation Fellowship
PUBLISHED 30 Apr 2019
https://doi.org/10.12688/f1000research.16679.1
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Recent advances in understanding phosphoinositide signaling in the nervous system
[version 1; peer review: 3 approved]
Eamonn James Dickson
Peer Reviewers Bernard Payrastre; Tamas Balla; Vytas A Bankaitis
  • Funders
  • University of California Funds
  • National Institute of General Medical Sciences
PUBLISHED 12 Mar 2019
https://doi.org/10.12688/f1000research.17023.1
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Tumour necrosis factor signalling in health and disease
[version 1; peer review: 2 approved]
Jonathan Holbrook, Samuel Lara-Reyna, Heledd Jarosz-Griffiths, Michael F. McDermott
Peer Reviewers Rudi Beyaert; Lisa Sedger
  • Funders
  • Leeds Institute of Medical Research (LIMR)
  • Consejo Nacional de Ciencia y Tecnología (CONACyT)
  • Cystic Fibrosis Trust
PUBLISHED 28 Jan 2019
https://doi.org/10.12688/f1000research.16793.1
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Recent advances in understanding intestinal stem cell regulation
[version 1; peer review: 3 approved]
Deqing Hu, Han Yan, Xi C He, Linheng Li
Peer Reviewers Rongwen Xi; Eduard Batlle; Ramesh A Shivdasani
  • Funders
  • National Natural Science Foundation of China
  • Natural Science Foundation of Tianjin
  • NIH
PUBLISHED 18 Jan 2019
https://doi.org/10.12688/f1000research.16190.1
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Positive and negative regulation of Shh signalling in vertebrate retinal development
[version 1; peer review: 3 approved]
Viviana E Gallardo, Paola Bovolenta
Peer Reviewers Valerie A Wallace; Michel Cayouette; Andrew J. Waskiewicz
  • Funders
  • ERA-Net Neuron
  • Fundación Ramón Areces
  • H2020-MSCA-IF-2016
  • Ministerio de Economía y Competitividad
PUBLISHED 14 Dec 2018
https://doi.org/10.12688/f1000research.16439.1
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Recent advances in understanding inhibitor of apoptosis proteins
[version 1; peer review: 2 approved]
Najoua Lalaoui, David Lawrence Vaux
Peer Reviewers Christine J Hawkins; Mads Gyrd-Hansen
  • Funders
  • Cancer Australia and Cure Cancer Australia Foundation
  • Victorian State Government Operational Infrastructure Support (OIS).
  • Victorian Cancer Agency
  • Australian Government Independent Medical Research Institutes Infrastructure Support Scheme (IRIISS)
  • National Health and Medical Research Council
  • Leukemia and Lymphoma Society SCOR
PUBLISHED 03 Dec 2018
https://doi.org/10.12688/f1000research.15782.1
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Cell–cell adhesion: linking Wnt/β-catenin signaling with partial EMT and stemness traits in tumorigenesis
[version 1; peer review: 4 approved]
Sayon Basu, Sanith Cheriyamundath, Avri Ben-Ze’ev
Peer Reviewers Paul B Fisher; Margot Zöller; Pasdar Manijeh; Walter Birchmeier
  • Funders
  • Israel Science Foundation
  • Israel Cancer Research Fund
PUBLISHED 18 Sep 2018
https://doi.org/10.12688/f1000research.15391.1
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Establishing sharp and homogeneous segments in the hindbrain
[version 1; peer review: 3 approved]
David G. Wilkinson
Peer Reviewers Robb Krumlauf; Kyo Yamasu; Dalit Sela-Donenfeld
  • Funders
  • UK Medical Research Council
  • Wellcome Trust
  • Cancer Research UK
PUBLISHED 13 Aug 2018
https://doi.org/10.12688/f1000research.14136.1
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Re-highlighting the action of PPARγ in treating metabolic diseases
[version 1; peer review: 2 approved]
Sung Hee Choi, Sung Soo Chung, Kyong Soo Park
Peer Reviewers Laszlo Nagy and Attila Pap; Alexander Orekhov
  • Funder
  • Ministry of Science and ICT, Republic of Korea
PUBLISHED 24 Jul 2018
https://doi.org/10.12688/f1000research.14143.1
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A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination
[version 1; peer review: 4 approved]
Allen Zinkle, Moosa Mohammadi
Peer Reviewers Lars Rönnstrand; Xin Zhang; Harukazu Nakamura; Kalina Hristova
  • Funder
  • National Institutes of Health
PUBLISHED 21 Jun 2018
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