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https://doi.org/10.12688/f1000research.164241.2
Study Protocol metrics
Revised
OnabotulinumtoxinA blockade of the sphenopalatine ganglion in treatment-resistant chronic migraine (MiBlock): rationale, design and study protocol for a multi-centre, investigator initiated, randomised, quadruple-blinded placebo-controlled trial.
[version 2; peer review: 1 approved, 1 approved with reservations]
Tore Wergeland, Melanie Simpson, Irina Aschehoug, Lise Øie, Sozaburo Hara, Einar Tobias Vassbø Skalstad, Øyvind Salvesen, Erling Tronvik, Daniel Bratbak
Peer Reviewers Lanfranco Pellesi; Keiko Ihara
  • Funder
  • the Norwegian National Program for Clinical Therapy Research, KLINBEFORSK
LATEST VERSION PUBLISHED 05 Feb 2026
https://doi.org/10.12688/f1000research.174946.1
Review metrics AWAITING PEER REVIEW
Mechanisms of Neuroimmune Interactions in Stress Physiology, Health Implications, and Emerging Therapeutic Targets.
[version 1; peer review: awaiting peer review]
Regan Mujinya, Swase Dominic Terkimbi, Elna Owembabazi, Swabra Yahya Umutoni, Joseph Kibirige, Partick Maduabuchi Aja, Victor Otu Oka, Daniel Udofia Owu
Peer Reviewers Invited
PUBLISHED 03 Feb 2026
https://doi.org/10.12688/f1000research.174232.1
Research Article metrics AWAITING PEER REVIEW
Emotion Detection of People with Autism Ages 10–20: Using Beta-Left and Gamma-Right Temporal
[version 1; peer review: awaiting peer review]
Omayya Murad, Mohammad Malkawi, Methaq Khadum, Nour Faouel, Khalid Batterjee, Samer Dashi, Hala Leberrara, Ahmad Arafat
Peer Reviewers Invited
  • Funder
  • Federation of Arab Scientific Research Councils (FASRC)
PUBLISHED 28 Jan 2026
https://doi.org/10.12688/f1000research.173446.1
Research Article metrics AWAITING PEER REVIEW
Pathophysiological Effects of Titanium Dioxide Nanoparticles and the Protective Role of Piperine and a Piperine-TiO₂NP Combination in Rats.
[version 1; peer review: awaiting peer review]
Ahmed Jasim Nawfal, Zahraa S. Mahdi, Rafid Khalid Ali
Peer Reviewers Invited
PUBLISHED 21 Jan 2026
https://doi.org/10.12688/f1000research.176642.1
Research Article metrics AWAITING PEER REVIEW
Seizure-Free Status Predicts Safe Ramadan Fasting in Epilepsy: A Multicenter Prospective Cohort from Indonesia
[version 1; peer review: awaiting peer review]
Fitri Octaviana, Kheng Seang Lim, Ismi Adhanisa Hamdani, Gotot Sumantri, Izati Rahmi, Andre ., Winnugroho Wiratman, Luh Ari Indrawati, Adrian Ridski Harsono, Astri Budikayanti
Peer Reviewers Invited
  • Funder
  • Universitas Indonesia
PUBLISHED 20 Jan 2026
https://doi.org/10.12688/f1000research.169308.2
Research Article metrics
Revised
Bromelain Restores Glutamatergic Homeostasis via Regulation of NR2A, GLT-1, EAAC1, and xCT in Arsenic-Induced Cerebral Cortex and Hippocampal Neurotoxicity
[version 2; peer review: 2 approved, 1 approved with reservations]
Anyanwu Emeka Godson, Kpokuechukwu Chinua Ogonnadi, Augustine Uchenna Agu, Nto Johnson Nto, Ikechukwu Aniaku, Yadilichi Yvonne Nwabueze, Vivian Onyinye Ojiakor, Anyanwu Chinyere Nkemjika
Peer Reviewers Yousef Mohammed Aljohani; Melissa Hernández-Frausto; Tak Pan Wong
LATEST VERSION PUBLISHED 31 Dec 2025
https://doi.org/10.12688/f1000research.167865.1
Research Article metrics AWAITING PEER REVIEW
Evaluating the use of Getting It right first time GIRFT guidelines in suspected Cauda Equina Syndrome CES at a London District General Hospital DGH
[version 1; peer review: awaiting peer review]
Wassim Abdou, Soushma Seeburuth, Henry Bowyer, Ajeet Kumar
Peer Reviewers Invited
PUBLISHED 24 Dec 2025
https://doi.org/10.12688/f1000research.173387.1
Research Article metrics AWAITING PEER REVIEW
Serum Neurogranin as a Diagnostic Biomarker for Acute Ischemic Stroke: Performance Comparison Between Thrombotic and Embolic subtypes
[version 1; peer review: awaiting peer review]
Tiba H. Saleh, Namir I. A. Haddad
Peer Reviewers Invited
PUBLISHED 18 Dec 2025
https://doi.org/10.12688/f1000research.150498.2
Case Report metrics
Revised
Case Report: Creutzfeldt-Jakob disease and diagnosis challenges: case report and evidence synthesis
[version 2; peer review: 2 approved]
Virgilio E Failoc Rojas, Yiro Yazawa-Ballena, Gustavo Alvarado-Moreno, Alba Navarro-Flores, Carlos Alva-Diaz, Kevin Pacheco-Barrios
Peer Reviewers Anna Ladogana; Shi-Lin Yang
LATEST VERSION PUBLISHED 09 Dec 2025
https://doi.org/10.12688/f1000research.167964.1
Case Study metrics
Sneezing in response to naturalistic bright light exposure
[version 1; peer review: 2 approved with reservations]
Lucien Bickerstaff, Josef Trinkl, Stephan Munkwitz, Manuel Spitschan
Peer Reviewers Arnold Wilkins; Zacharias Kalentakis
  • Funder
  • Max-Planck-Gesellschaft
PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.160416.3
Research Article metrics
Revised
Ginkgo Biloba as a niche theme cognitive enhancer agent, 1420 dokumen of Scopus database. A bibliometric study from 1988 to 2024
[version 3; peer review: 2 approved]
ARMAN YURISALDI SALEH, Dwi Arwandi Yogi Saputra, Riezky Valentina, Tirta Darmawan Susanto
Peer Reviewers tasawar iqbal; Arne Reimers
LATEST VERSION PUBLISHED 15 Oct 2025
https://doi.org/10.12688/f1000research.166549.1
Research Article metrics
Utilizing anatomical information for signal detection in functional magnetic resonance imaging
[version 1; peer review: 2 approved with reservations, 1 not approved]
Norman Peitek, André Brechmann, Karsten Tabelow, Thorsten Dickhaus
Peer Reviewers Benedikt Sundermann; Fabricio Cravo and Stephanie Noble; Qiran Jia
  • Funder
  • Deutsche Forschungsgemeinschaft
PUBLISHED 01 Oct 2025
https://doi.org/10.12688/f1000research.169799.1
Research Article metrics
Shining Light into Adolescent HIV Neuroplasticity: A Study of the Prefrontal Cortex Using Functional Near Infrared Spectrometry
[version 1; peer review: 3 approved with reservations]
Sizwe Zondo, Kate Cockcroft, Candida da Silva Ferreira Barreto, Aline Ferreira Correia
Peer Reviewers Nerrolyn Ramstrand; Kaylee Van Wyhe; Taylor Fitzpatrick-Schmidt
  • Funders
  • University of the Witwatersrand, Johannesburg
  • Rhodes University
  • National Research Foundation
PUBLISHED 29 Sep 2025
https://doi.org/10.12688/f1000research.166417.2
Research Article metrics
Registered report
Revised
Stage 2 Registered Report: Refinement of tickling protocols to improve positive animal welfare in laboratory rats
[version 2; peer review: 2 approved]
Vincent Bombail, Sarah M Brown, Cammy Beyts, Jessica E Martin, Tianhao Li, Simone L Meddle, Michael Mendl, Emma SJ Robinson, Tayla J Hammond, Birte L Nielsen, Megan R LaFollette, Ignacio Vinuela-Fernandez, Emma KL Tivey, Alistair B Lawrence
Peer Reviewers Sergio Pellis; Carla Forte Maiolino Molento
  • Funder
  • NC3Rs
LATEST VERSION PUBLISHED 23 Sep 2025
https://doi.org/10.12688/f1000research.169688.1
Research Article metrics AWAITING PEER REVIEW
Montelukast altered BDNF and CHRNA7 gene expression were associated with behavioral changes in rats.
[version 1; peer review: awaiting peer review]
Karar Haider, Yassir Mustafa Kamal Al Mulla Hummadi, Rihab Muhamad Guaim, Mutaz Ahmeid
Peer Reviewers Invited
PUBLISHED 22 Sep 2025
https://doi.org/10.12688/f1000research.127413.2
Research Article metrics
Revised
Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats)
[version 2; peer review: 2 approved, 1 not approved]
Asadullah Asadullah, Abdul Hafid Bajamal, Muhammad Arifin Parenrengi, Agus Turchan, Budi Utomo, I Ketut Sudiana, Eko Agus Subagio
Peer Reviewers Mawaddah Ar Rochmah; Cafer Ikbal Gulsever; Xue Yao
LATEST VERSION PUBLISHED 22 Sep 2025
https://doi.org/10.12688/f1000research.157890.2
Systematic Review metrics
Revised
Developing treatments for cerebral small vessel disease: a scoping review of licensed interventions for potential repurposing
[version 2; peer review: 2 approved]
Philip M Bath, Elizabeth P Phan, Gwynneth Clay, Jesse Dawson, Paresh Malhotra, Rob Howard, Suvankar Pal, Joanna M Wardlaw, Terry Quinn, Malcolm Macleod
Peer Reviewers Jade L. Taylor; Maria Clara Zanon Zotin
LATEST VERSION PUBLISHED 10 Sep 2025
https://doi.org/10.12688/f1000research.166556.1
Research Article metrics
Detection Rate of Human Papilloma Virus Genotype 16 / 18 infections in Brain Tissues from a group of Iraqi Patients with Glioblastoma Multiforme: An In Situ Hybridization Study.
[version 1; peer review: 2 approved with reservations]
Sarmad M.H. Zeiny, Ali K. Al-Shalchy, Saad Hasan Mohammed Ali, Shakir H. Mohammed Al-Alwany, Athraa Y. Al-Hijazi
Peer Reviewers Raziye Piranlioglu and Emerenziana Runco; Lucia E. Azuara-Alvarez and Giovanni Palomino Vizcaino
  • Funder
  • none
PUBLISHED 03 Sep 2025
https://doi.org/10.12688/f1000research.163638.2
Systematic Review metrics
Revised
Exploring mean kurtosis in MR diffusion kurtosis imaging for early detection of lumbar spine degeneration: a systematic review
[version 2; peer review: 2 approved]
Neil Abraham Barnes, Winniecia Dkhar, Rajagopal Kadavigere, Suresh Sukumar, Abhimanyu Pradhan, Priya P.S., Vaishali K
Peer Reviewers Priyanka Chandrasekhar; Manna Debnath
  • Funder
  • The authors did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors
LATEST VERSION PUBLISHED 01 Sep 2025
https://doi.org/10.12688/f1000research.164444.1
Research Article metrics
Linezolid-associated optic neuropathy in drug-resistant tuberculosis patients in Sulianti Saroso Infectious Disease Hospital
[version 1; peer review: 1 approved, 1 approved with reservations]
Emilia Setyaadmadja, Yunita Sari, Ardhika Prasetya, Rosamarlina -, Pompini Agustina Sitompul, Adria Rusli, Titi Sundari, Faisal Matondang, Haruyuki Dewi Faisal, Siti Maemun
Peer Reviewers Gyanshankar Mishra; Zen Ahmad
  • Funder
  • No
PUBLISHED 13 Aug 2025
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