Bioinformatics

Bioinformatics

Transcriptomics

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 in 
https://doi.org/10.12688/f1000research.182343.1
Review metrics AWAITING PEER REVIEW
Where are we after 15 years of minimally invasive skin sampling? A fit-for-purpose review of microbiopsy research from concept to the clinic.
[version 1; peer review: awaiting peer review]
Miko Yamada, Vidiya Dev, Max E. Nobel, Frances E. Pearson, Alison Layton, Tarl Prow
Peer Reviewers Invited
PUBLISHED 24 Jun 2026
https://doi.org/10.12688/f1000research.179899.1
Software Tool Article metrics
TagGen: High-Performance Barcode Generator and Demultiplexer for High-Throughput and Long-Read Sequencing Applications
[version 1; peer review: 1 approved, 1 not approved]
Faiza Chowdhury, Tessa Swain, Roderik Shirokikh, Danielle Rudler, Archa Fox, Alice Cleynen, Nikolay Shirokikh
Peer Reviewers Zhenxian Zheng; Umut Yildiz
  • Funders
  • National Health and Medical Research Council of Australia (NHMRC)
  • Australian Research Council (ARC)
  • European Union’s Horizon 2020
  • Bootes Foundation
PUBLISHED 30 Apr 2026
https://doi.org/10.12688/f1000research.175162.1
Software Tool Article metrics
Spotsweeper-py: spatially-aware quality control metrics for spatial omics data in the Python ecosystem
[version 1; peer review: 2 approved with reservations]
Xingyi Chen, Michael Totty, Stephanie Hicks
Peer Reviewers Patrick Murigu Kamau Njage; Ayshwarya Subramanian and Adam Zuchowski
  • Funders
  • National Institute of Mental Health
  • National Institute of General Medical Sciences
PUBLISHED 09 Jan 2026
https://doi.org/10.12688/f1000research.175457.1
Brief Report metrics
lncRNA CHASERR Integrates Transcriptional and Post-Transcriptional Gene Regulation
[version 1; peer review: 2 not approved]
Anna Budkina, Anatoliy Zubritskiy, Yulia A. Medvedeva
Peer Reviewers Anna M Krichevsky and Evgeny Deforzh; Hober Nelson Núñez-Martínez
  • Funder
  • Russian Science Foundation
PUBLISHED 30 Dec 2025
https://doi.org/10.12688/f1000research.163212.2
Data Note metrics
Revised
CD4+ T-cell transcription factors as early predictors of phenoconversion in idiopathic rapid eye movement sleep behaviour disorder
[version 2; peer review: 2 approved]
Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino
Peer Reviewers Tommaso Schirinzi; Adawiya J. Haider
LATEST VERSION PUBLISHED 06 Oct 2025
https://doi.org/10.12688/f1000research.164530.1
Research Article metrics
Inferring and simulating a gene regulatory network for the sympathoadrenal differentiation from single-cell transcriptomics in human.
[version 1; peer review: 1 approved with reservations]
Olivier Gandrillon
Peer Reviewers Olivia Johnson
  • Funder
  • Ligue Contre le Cancer
PUBLISHED 11 Sep 2025
https://doi.org/10.12688/f1000research.155223.2
Review metrics
Revised
Selecting differential splicing methods: Practical considerations for short-read RNA sequencing
[version 2; peer review: 2 approved, 3 approved with reservations]
Ben J. Draper, Mark J. Dunning, David C. James
Peer Reviewers Stefano Donega; Charlotte Capitanchik; Julia Olivieri; Zhaoqi Liu; Monica Salinas and Juan Valcarcel
  • Funders
  • Lonza Biologics plc
  • University of Sheffield
LATEST VERSION PUBLISHED 30 May 2025
https://doi.org/10.12688/f1000research.153698.1
Software Tool Article metrics
scRICA: An R package for multiple-sample single-cell RNA-seq data integrative comparative analysis
[version 1; peer review: 1 approved with reservations, 1 not approved]
Yan Li, Jason Shapiro, Qiaoshan Lin, Qing Gong, Michiko Ryu, Mengjie Chen
Peer Reviewers Pedro L Baldoni; Sebastiaan Valkiers
  • Funders
  • University of Chicago
  • National Institutes of Health
  • Institute for Translational Medicine
PUBLISHED 20 Jan 2025
https://doi.org/10.12688/f1000research.149237.1
Software Tool Article metrics
ZARP: A user-friendly and versatile RNA-seq analysis workflow
[version 1; peer review: 2 approved with reservations]
Maria Katsantoni, Foivos Gypas, Christina J Herrmann, Dominik Burri, Maciej Bąk, Paula Iborra, Krish Agarwal, Meriç Ataman, Máté Balajti, Noè Pozzan, Niels Schlusser, Youngbin Moon, Aleksei Mironov, Anastasiya Börsch, Mihaela Zavolan, Alexander Kanitz
Peer Reviewers Silvia Liu; Bo Li
  • Funders
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
  • National Center of Competence in Research RNA & Disease
PUBLISHED 24 May 2024
https://doi.org/10.12688/f1000research.74416.2
Software Tool Article metrics
Revised
BASiCS workflow: a step-by-step analysis of expression variability using single cell RNA sequencing data
[version 2; peer review: 1 approved, 2 approved with reservations]
Alan O'Callaghan, Nils Eling, John C. Marioni, Catalina A. Vallejos
Peer Reviewers Oliver M. Crook; Andrew McDavid; Michel S Naslavsky
  • Funders
  • Cancer Research UK
  • University of Edinburgh
  • European Molecular Biology Laboratory
LATEST VERSION PUBLISHED 07 May 2024
https://doi.org/10.12688/f1000research.126215.2
Method Article metrics
Revised
Bayesian Multi-View Clustering given complex inter-view structure
[version 2; peer review: 2 approved]
Benjamin D. Shapiro, Alexis Battle
Peer Reviewers Sara Mostafavi; Max Moldovan
  • Funders
  • Microsoft
  • National Institute of General Medical Sciences
LATEST VERSION PUBLISHED 29 Feb 2024
https://doi.org/10.12688/f1000research.131861.2
Research Article metrics
Revised
Single-cell transcriptional uncertainty landscape of cell differentiation
[version 2; peer review: 2 approved]
Nan Papili Gao, Olivier Gandrillon, András Páldi, Ulysse Herbach, Rudiyanto Gunawan
Peer Reviewers Alessandro Giuliani; Geneviève Dupont
  • Funders
  • Swiss National Science Foundation
  • Agence Nationale de la Recherche
LATEST VERSION PUBLISHED 20 Jul 2023
https://doi.org/10.12688/f1000research.122949.2
Software Tool Article metrics
Revised
DEVEA: an interactive shiny application for Differential Expression analysis, data Visualization and Enrichment Analysis of transcriptomics data
[version 2; peer review: 2 approved]
Miriam Riquelme-Perez, Fernando Perez-Sanz, Jean-François Deleuze, Carole Escartin, Eric Bonnet, Solène Brohard
Peer Reviewers Hélène Hirbec; Wenbin Guo
  • Funder
  • PhD fellowship from the CEA (Amont-Aval).
LATEST VERSION PUBLISHED 24 Mar 2023
https://doi.org/10.12688/f1000research.110492.2
Research Article metrics
Revised
From head to rootlet: comparative transcriptomic analysis of a rhizocephalan barnacle Peltogaster reticulata (Crustacea: Rhizocephala)
[version 2; peer review: 2 approved]
Maksim Nesterenko, Aleksei Miroliubov
Peer Reviewers Andreas Hejnol and Ferenc Kagan; Viatcheslav Ivanenko
  • Funder
  • Russian Science Foundation
LATEST VERSION PUBLISHED 09 Jan 2023
https://doi.org/10.12688/f1000research.51749.2
Method Article metrics
Revised
satuRn: Scalable analysis of differential transcript usage for bulk and single-cell RNA-sequencing applications
[version 2; peer review: 2 approved]
Jeroen Gilis, Kristoffer Vitting-Seerup, Koen Van den Berge, Lieven Clement
Peer Reviewers Marek Cmero; Alejandro Reyes
  • Funders
  • Belgian American Educational Foundation
  • Fonds Wetenschappelijk Onderzoek
LATEST VERSION PUBLISHED 08 Aug 2022
https://doi.org/10.12688/f1000research.52173.4
Software Tool Article metrics
Revised
target: an R package to predict combined function of transcription factors
[version 4; peer review: 1 approved, 1 approved with reservations]
Mahmoud Ahmed, Deok Ryong Kim
Peer Reviewers Shulan Tian and Yan Huihuang; Mireia Ramos-Rodríguez
  • Funder
  • National Research Foundation of Korea
LATEST VERSION PUBLISHED 03 Aug 2022
https://doi.org/10.12688/f1000research.111175.2
Software Tool Article metrics
Revised
DSMZCellDive: Diving into high-throughput cell line data
[version 2; peer review: 2 approved]
Julia Koblitz, Wilhelm G. Dirks, Sonja Eberth, Stefan Nagel, Laura Steenpass, Claudia Pommerenke
Peer Reviewers Beate Rinner; Arihiro Kohara
  • Funder
  • Leibniz SAW project DiASPora
LATEST VERSION PUBLISHED 20 Jul 2022
https://doi.org/10.12688/f1000research.75321.1
Method Article metrics
Improving prediction of core transcription factors for cell reprogramming and transdifferentiation
[version 1; peer review: 2 not approved]
Mikhail Raevskiy, Anna Kondrashina, Yulia Medvedeva
Peer Reviewers Valentiva Boeva and Samuel Gunz; Erdem B. Dashinimaev
  • Funder
  • Ministry of Science and Higher Education of the Russian Federation
PUBLISHED 13 Jan 2022
https://doi.org/10.12688/f1000research.74836.1
Method Article metrics
Slinker: Visualising novel splicing events in RNA-Seq data
[version 1; peer review: 3 approved]
Breon Schmidt, Marek Cmero, Paul Ekert, Nadia Davidson, Alicia Oshlack
Peer Reviewers George Wiggins; Stephen Montgomery; Amy Huei-Yi Lee
  • Funder
  • NHMRC
PUBLISHED 07 Dec 2021
https://doi.org/10.12688/f1000research.28142.2
Software Tool Article metrics
Revised
MIREyA: a computational approach to detect miRNA-directed gene activation
[version 2; peer review: 1 approved, 2 approved with reservations]
Anna Elizarova, Mumin Ozturk, Reto Guler, Yulia A. Medvedeva
Peer Reviewers Michiel Jan Laurens De Hoon; Xiangfu Zhong; Chaogang Shao
  • Funders
  • European and Developing Countries Clinical Trials Partnership
  • Russian Foundation for Basic Research
  • South Africa National Research Foundation
LATEST VERSION PUBLISHED 26 Aug 2021
1-20 of 24 ARTICLES
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    The Methods and Tools Gateway Area will allow researchers to publish outputs concerning both the application and research into the use of various computational methods to analyse quantities of biological data for a range of different results, including predictions and discoveries. Read more keyboard_arrow_right
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