Bioinformatics

Bioinformatics

Methods and Tools

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https://doi.org/10.12688/f1000research.52531.1
Opinion Article metrics
Developing open-source software for bioimage analysis: opportunities and challenges
[version 1; peer review: 2 approved]
Florian Levet, Anne E. Carpenter, Kevin W. Eliceiri, Anna Kreshuk, Peter Bankhead, Robert Haase
Peer Reviewers Loïc A. Royer; Nico Stuurman
  • Funders
  • Deutsche Forschungsgemeinschaft
  • Institut National de la Santé et de la Recherche Médicale
  • National Institutes of Health
  • Chan Zuckerberg Initiative
PUBLISHED 19 Apr 2021
https://doi.org/10.12688/f1000research.27062.2
Software Tool Article metrics
Revised
SAPHIR: a Shiny application to analyze tissue section images
[version 2; peer review: 2 approved]
Elodie Germani, Hugues Lelouard, Mathieu Fallet
Peer Reviewers Mahmoud Ahmed; Seth Winfree
  • Funders
  • Agence Nationale de la Recherche
  • Aix-Marseille University
  • Fondation pour la Recherche Médicale
  • Centre National de la Recherche Scientifique and Institut National de la Santé et de la Recherche Médicale
LATEST VERSION PUBLISHED 08 Apr 2021
https://doi.org/10.12688/f1000research.25447.2
Software Tool Article metrics
Revised
DEVILS: a tool for the visualization of large datasets with a high dynamic range
[version 2; peer review: 2 approved]
Romain Guiet, Olivier Burri, Nicolas Chiaruttini, Olivier Hagens, Arne Seitz
Peer Reviewers Sebastien Tosi; Mehedi Masud
  • Funder
  • Norges Forskningsråd
LATEST VERSION PUBLISHED 22 Mar 2021
https://doi.org/10.12688/f1000research.51916.1
Software Tool Article metrics
CytoBrowser: a browser-based collaborative annotation platform for whole slide images
[version 1; peer review: 1 approved with reservations, 1 not approved]
Christopher Rydell, Joakim Lindblad
Peer Reviewers Simon Nørrelykke; Peter Bankhead
  • Funder
  • Sweden’s Innovation Agency, VINNOVA
PUBLISHED 22 Mar 2021
https://doi.org/10.12688/f1000research.50798.1
Software Tool Article metrics
Interactive biomedical segmentation tool powered by deep learning and ImJoy
[version 1; peer review: 1 approved, 1 approved with reservations]
Wei Ouyang, Trang Le, Hao Xu, Emma Lundberg
Peer Reviewers Jean-Yves Tinevez and Dmitry Ershov; Jan Funke
  • Funders
  • Knut and Alice Wallenberg Foundation
  • Swedish Research Council
  • LST Platform at KTH Royal Institute of Technology
PUBLISHED 24 Feb 2021
https://doi.org/10.12688/f1000research.26872.2
Software Tool Article metrics
Revised
Fiji plugins for qualitative image annotations: routine analysis and application to image classification
[version 2; peer review: 2 approved, 1 approved with reservations]
Laurent S. V. Thomas, Franz Schaefer, Jochen Gehrig
Peer Reviewers Jan Eglinger; Christian Tischer and Aliaksandr Halavatyi; Elisabet Teixido
  • Funder
  • Horizon 2020
LATEST VERSION PUBLISHED 12 Feb 2021
https://doi.org/10.12688/f1000research.25713.2
Software Tool Article metrics
Revised
VIRdb 2.0: Interactive analysis of comorbidity conditions associated with vitiligo pathogenesis using co-expression network-based approach
[version 2; peer review: 1 approved, 2 approved with reservations]
Priyansh Srivastava, Mehak Talwar, Aishwarya Yadav, Alakto Choudhary, Sabyasachi Mohanty, Samuel Bharti, Priyanka Narad, Abhishek Sengupta
Peer Reviewers Dinesh Gupta; Mitesh Dwivedi and Rasheedunnisa Begum; Animesh A Sinha
LATEST VERSION PUBLISHED 01 Feb 2021
https://doi.org/10.12688/f1000research.21782.4
Research Article metrics
Update
Benchmarking of long-read assemblers for prokaryote whole genome sequencing
[version 4; peer review: 4 approved]
Ryan R. Wick, Kathryn E. Holt
Peer Reviewers Aleksey V. Zimin and Steven Salzberg; Robert Vaser and Mile Šikić; Mikhail Kolmogorov; Olin Silander
  • Funders
  • Department of Education, Employment and Workplace Relations, Australian Government
  • Sylvia and Charles Viertel Charitable Foundation
  • Gates Foundation
LATEST VERSION PUBLISHED 01 Feb 2021
https://doi.org/10.12688/f1000research.21142.2
Software Tool Article metrics
Revised
Falco: high-speed FastQC emulation for quality control of sequencing data
[version 2; peer review: 2 approved]
Guilherme de Sena Brandine, Andrew D. Smith
Peer Reviewers R Henrik Nilsson; Weihong Qi
LATEST VERSION PUBLISHED 27 Jan 2021
https://doi.org/10.12688/f1000research.26429.2
Software Tool Article metrics
Revised
netDx: Software for building interpretable patient classifiers by multi-'omic data integration using patient similarity networks
[version 2; peer review: 2 approved]
Shraddha Pai, Philipp Weber, Ruth Isserlin, Hussam Kaka, Shirley Hui, Muhammad Ahmad Shah, Luca Giudice, Rosalba Giugno, Anne Krogh Nøhr, Jan Baumbach, Gary D. Bader
Peer Reviewers Kim-Anh Lê Cao; Anais Baudot, Judith Lambert and Laurent Tichit
  • Funders
  • Villum Fonden
  • Horizon 2020
  • National Institutes of Health
LATEST VERSION PUBLISHED 22 Jan 2021
https://doi.org/10.12688/f1000research.24187.2
Software Tool Article metrics
Revised
ExploreModelMatrix: Interactive exploration for improved understanding of design matrices and linear models in R
[version 2; peer review: 3 approved]
Charlotte Soneson, Federico Marini, Florian Geier, Michael I. Love, Michael B. Stadler
Peer Reviewers Jean Fan; Lucy D'Agostino McGowan; Matthew Ritchie
  • Funders
  • National Institutes of Health
  • German Federal Ministry of Education and Research
LATEST VERSION PUBLISHED 16 Sep 2020
https://doi.org/10.12688/f1000research.18490.3
Research Article metrics
Revised
Evaluation of methods to assign cell type labels to cell clusters from single-cell RNA-sequencing data
[version 3; peer review: 2 approved, 1 approved with reservations]
J. Javier Diaz-Mejia, Elaine C. Meng, Alexander R. Pico, Sonya A. MacParland, Troy Ketela, Trevor J. Pugh, Gary D. Bader, John H. Morris
Peer Reviewers Saskia Freytag; Jimmy Tsz Hang Lee and Tallulah Andrews; Lindsay Cowell
  • Funders
  • National Resource for Network Biology
  • Chan Zuckerberg Initiative
LATEST VERSION PUBLISHED 14 Oct 2019
https://doi.org/10.12688/f1000research.11290.1
Research Article metrics
Gene length and detection bias in single cell RNA sequencing protocols
[version 1; peer review: 4 approved]
Belinda Phipson, Luke Zappia, Alicia Oshlack
Peer Reviewers Charlotte Soneson;  Samuel W. Lukowski; Wolfgang Huber; Sam Buckberry and Timothy Stuart
  • Funders
  • National Health and Medical Research Council
  • Australian Federal Government
PUBLISHED 28 Apr 2017
61-73 of 73 ARTICLES
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Gateway Areas
  • Methods and Tools
    The Methods and Tools Gateway Area will allow researchers to publish outputs concerning both the application and research into the use of various computational methods to analyse quantities of biological data for a range of different results, including predictions and discoveries. Read more keyboard_arrow_right
  • Genetics and Genomics
    The Genetics & Genomics Gateway Area will enable researchers to publish content related to the analysis, storage and accessibility of DNA, RNA and protein sequences. This analysis can be conducted in a variety of ways, including comparison of sequences and relationships, identification of functions, and recognition of patterns across the samples. Read more keyboard_arrow_right
  • Transcriptomics
    By curating all outputs related to the analysis of the RNA transcripts produced by a genotype, the Transcriptomics Gateway Area will allow readers to easily access content pertinent to this research. Read more keyboard_arrow_right
  • Proteomics
    The Proteomics Gateway Area has been established to allow authors to access and publish research content related to the large-scale study of entire sets of proteins as proteomes. Read more keyboard_arrow_right
  • Metagenomics
    This Gateway Area will allow members of the bioinformatics community to collate all research related to the collection of genomes from an environmental sample. Read more keyboard_arrow_right
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