Bioinformatics

Bioinformatics

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121-140 of 377 ARTICLES
https://doi.org/10.12688/f1000research.73600.2
Software Tool Article metrics
Revised
Doublet identification in single-cell sequencing data using scDblFinder
[version 2; peer review: 2 approved]
Peer Reviewers Zev J. Gartner and Chris McGinnis; Dennis Kostka and Hannah Schriever
  • Funder
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
LATEST VERSION PUBLISHED 16 May 2022
https://doi.org/10.12688/f1000research.114698.1
Method Article metrics
DeepReGraph co-clusters temporal gene expression and cis-regulatory elements through heterogeneous graph representation learning
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Wanding Zhou; Tallulah Andrews and Boris Tchatchoua Ngassam
  • Funders
  • Universidad Técnica Particular de Loja
  • ELIS Innovation Hub
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 13 May 2022
https://doi.org/10.12688/f1000research.108835.2
Software Tool Article metrics
Revised
SnakeWRAP: a Snakemake workflow to facilitate automated processing of metagenomic data through the metaWRAP pipeline
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Tobias Jakobi; Michael J Roach; Lauren Mak
LATEST VERSION PUBLISHED 28 Apr 2022
https://doi.org/10.12688/f1000research.110351.1
Brief Report metrics
High-quality genome assembly of a Pestalotiopsis fungus using DIY-friendly methods
[version 1; peer review: 3 approved with reservations]
Peer Reviewers Paula Maria Moolhuijzen; Huzefa A Raja; Sinem Beyhan
  • Funder
  • Mitacs
PUBLISHED 20 Apr 2022
https://doi.org/10.12688/f1000research.110936.1
Research Article metrics
TReNCo: Topologically associating domain (TAD) aware regulatory network construction
[version 1; peer review: 2 not approved]
Peer Reviewers Junbai Wang; Sonika Tyagi
  • Funders
  • National Institute of General Medical Sciences
  • Cancer Prevention and Research Institute of Texas
PUBLISHED 14 Apr 2022
https://doi.org/10.12688/f1000research.54449.2
Research Article metrics
Revised
Philympics 2021: Prophage Predictions Perplex Programs
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Franklin Nobrega; Karthik Anantharaman and Kristopher Kieft
  • Funder
  • NIH National Institute Of Diabetes And Digestive And Kidney Diseases
LATEST VERSION PUBLISHED 08 Apr 2022
https://doi.org/10.12688/f1000research.76154.1
Software Tool Article metrics
IsoAligner: dynamic mapping of amino acid positions across protein isoforms
[version 1; peer review: 2 approved with reservations]
Peer Reviewers James D Stephenson; Laurens van de Wiel
PUBLISHED 31 Mar 2022
https://doi.org/10.12688/f1000research.51494.2
Method Article metrics
Revised
The National Ecological Observatory Network’s soil metagenomes: assembly and basic analysis
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Naupaka Zimmerman; William Nelson; Olubukola Oluranti Babalola
  • Funder
  • National Science Foundation
LATEST VERSION PUBLISHED 23 Mar 2022
https://doi.org/10.12688/f1000research.39214.2
Opinion Article metrics
Revised
A roadmap for the generation of benchmarking resources for antimicrobial resistance detection using next generation sequencing
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Rene Hendriksen; Anna Abramova and Marcus Wenne; Enrico Lavezzo and Emilio Ispano
  • Funders
  • Biotechnology and Biological Sciences Research Counci
  • European Commission
LATEST VERSION PUBLISHED 16 Mar 2022
https://doi.org/10.12688/f1000research.84360.1
Review metrics
Automated human chromosome segmentation and feature extraction: Current trends and prospects
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Mousami Munot; Lamiaa Elrefae
PUBLISHED 11 Mar 2022
https://doi.org/10.12688/f1000research.74024.1
Research Article metrics
eTRANSAFE: Building a sustainable framework to share reproducible drug safety knowledge with the public domain
[version 1; peer review: 2 approved]
Peer Reviewers Merran Smith; Ishwar Chandramouliswaran
  • Funders
  • Innovative Medicines Initiative
  • Horizon 2020
PUBLISHED 07 Mar 2022
https://doi.org/10.12688/f1000research.83714.1
Software Tool Article metrics
pTITAN2: Permutation of treatment labels and Threshold Indicator Taxa ANalysis
[version 1; peer review: 1 approved, 1 not approved]
Peer Reviewers Cajo J. F. ter Braak; Jonathan A Walter
  • Funder
  • U.S. Environmental Protection Agency
PUBLISHED 02 Mar 2022
https://doi.org/10.12688/f1000research.23790.2
Method Article metrics
Revised
How to build phylogenetic species trees with OMA
[version 2; peer review: 2 approved]
Peer Reviewers Jianbo Xie; Denis Baurain
  • Funders
  • Swiss National Science Foundation
  • Swiss Institute of Bioinformatics
LATEST VERSION PUBLISHED 28 Feb 2022
https://doi.org/10.12688/f1000research.94159.1
Software Tool Article metrics
miND (miRNA NGS Discovery pipeline): a small RNA-seq analysis pipeline and report generator for microRNA biomarker discovery studies
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Kristian Almstrup, Nina Mørup and Ailsa Maria Main; Francisco J. Enguita
  • Funder
  • Innovative Medicines Initiative 2
PUBLISHED 24 Feb 2022
https://doi.org/10.12688/f1000research.28352.2
Method Article metrics
Revised
Methods for sequencing the pandemic: benefits of rapid or high-throughput processing
[version 2; peer review: 2 approved]
Peer Reviewers Bronwyn L. MacInnis; Keith Crandall
  • Funders
  • Arizona Department of Health Services
  • The NARBHA institute
LATEST VERSION PUBLISHED 21 Feb 2022
https://doi.org/10.12688/f1000research.75243.1
Software Tool Article metrics
SASCRiP: A Python workflow for preprocessing UMI count-based scRNA-seq data
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Fabiola Curion and Luke Zappia; Fangming Xie
  • Funder
  • National Research Foundation
PUBLISHED 15 Feb 2022
https://doi.org/10.12688/f1000research.107925.1
Software Tool Article metrics
NIFtHool: an informatics program for identification of NifH proteins using deep neural networks
[version 1; peer review: 2 approved]
Peer Reviewers Juan Onofre Orozco-López; Lorena Isabel Barona López
PUBLISHED 09 Feb 2022
https://doi.org/10.12688/f1000research.26452.1
Software Tool Article metrics
Lessons learned in virulence factor identification and data management from a hackathon on microbial virulence
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Rick Stevens and James Davis; Kevin Tyler
  • Funders
  • Fundação para a Ciência e a Tecnologia
  • Scientific and Technological Research Council of Turkey
  • Intramural Research Program of the National Library of Medicine
PUBLISHED 09 Feb 2022
https://doi.org/10.12688/f1000research.28225.2
Research Article metrics
Revised
Human Proteinase 3, an important autoantigen of c-ANCA associated vasculitis, shares cross-reactive epitopes with serine protease allergens from mites: an in silico analysis
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Chandrabose Selvaraj; Tomas Erban; Hiroshi Tanaka
  • Funder
  • Fondo Nacional de Financiamiento para la Ciencia, la Tecnología y la Innovación
LATEST VERSION PUBLISHED 03 Feb 2022
https://doi.org/10.12688/f1000research.79530.1
Software Tool Article metrics
bit: a multipurpose collection of bioinformatics tools
[version 1; peer review: 2 not approved]
Peer Reviewers Kai Zhang; Georges Hattab
PUBLISHED 31 Jan 2022
121-140 of 377 ARTICLES
Gateway Areas
  • Methods and Tools
    The Methods and Tools Gateway Area will allow researchers to publish outputs concerning both the application and research into the use of various computational methods to analyse quantities of biological data for a range of different results, including predictions and discoveries. Read more keyboard_arrow_right
  • Genetics and Genomics
    The Genetics & Genomics Gateway Area will enable researchers to publish content related to the analysis, storage and accessibility of DNA, RNA and protein sequences. This analysis can be conducted in a variety of ways, including comparison of sequences and relationships, identification of functions, and recognition of patterns across the samples. Read more keyboard_arrow_right
  • Transcriptomics
    By curating all outputs related to the analysis of the RNA transcripts produced by a genotype, the Transcriptomics Gateway Area will allow readers to easily access content pertinent to this research. Read more keyboard_arrow_right
  • Proteomics
    The Proteomics Gateway Area has been established to allow authors to access and publish research content related to the large-scale study of entire sets of proteins as proteomes. Read more keyboard_arrow_right
  • Metagenomics
    This Gateway Area will allow members of the bioinformatics community to collate all research related to the collection of genomes from an environmental sample. Read more keyboard_arrow_right
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