Research Article
metrics
Revised
Fraxin and Quercetin, separately and combined, reduced cytokine release in LPS-induced RAW 264.7 cell line through targeting TLR-4 and PPAR-ɣ
[version 2; peer review: 1 approved with reservations, 1 not approved]
Peer Reviewers
Dr. Amany Ghazy;
Fan Jiang
Method Article
metrics
Revised
Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening.
[version 2; peer review: 2 approved]
Peer Reviewers
Ulrich Jarry;
Stuart A. Clayton
- Funders
- National Centre for the Replacement Refinement and Reduction of Animals in Research
- North West Cancer Research
Research Article
metrics
Revised
The potential effects of cranberry extract on indomethacin-induced gastric ulcer in rats
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Suraj N Mali;
Vishal Dubey;
Vijayakumar A. R
Research Article
metrics
Revised
Tumor-driven stromal reprogramming in the pre-metastatic lymph node
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Sanjiv Luther;
Christopher McGinnis
Research Article
metrics
Revised
Regulation of MAP2, GFAP, and calcium in the CA3 Region Following Kainic Acid Exposure to organotypic hippocampal slice culture
[version 3; peer review: 2 approved]
Peer Reviewers
Abdul Gofir;
Amin Derouiche
Study Protocol
metrics
Revised
Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Daniel Foster;
William Messer;
Xiaonan Guo
- Funders
- Bundesministerium für Bildung und Forschung
- Medical Research Council-UK
- Federal Ministry of Education and Research
- Wellcome Trust
Research Article
metrics
Revised
In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease
[version 2; peer review: 3 approved, 1 not approved]
Peer Reviewers
Sailu Sarvagalla;
Yassir Boulaamane and Iman Touati;
Abdul Rajjak Shaikh;
James Adams
- Funder
- Thailand Science Research and Innovation Fund Chulalongkorn University
Opinion Article
metrics
Revised
Viral interactions with host factors (TIM-1, TAM -receptors, Glut-1) are related to the disruption of glucose and ascorbate transport and homeostasis, causing the haemorrhagic manifestations of viral haemorrhagic fevers.
[version 6; peer review: 2 approved]
Peer Reviewers
Hong-Li Liu;
Chao Qin
Review
metrics
Revised
Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease.
[version 2; peer review: 1 approved, 3 approved with reservations]
Peer Reviewers
Mateusz S. Wietecha;
Valentina Pucino;
Spyridon Makris;
George Kollias
- Funders
- Medicine by Design
- Canadian Institutes of Health Research
Brief Report
metrics
Investigating the Role of MUC19 in Glioblastoma Multiforme: Genetic Alterations and Implications for Patient Survival and Therapeutic Targeting
[version 1; peer review: 1 approved]
Peer Reviewers
Amna Makawi
Research Article
metrics
Revised
Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mouse placentas
[version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved]
Peer Reviewers
Ludivine Doridot;
Berthold Huppertz;
Lisa Akison and Sarah Steane;
Johannes van der Merwe
- Funder
- CONACYT
Research Article
metrics
Revised
Unraveling the genetic basis of antibiotic resistance in Staphylococcus aureus: Focus on mecA and PVL Genes
[version 2; peer review: 2 approved with reservations]
Peer Reviewers
Heather B. Miller;
Xiancai Rao
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation
[version 4; peer review: 2 approved]
Peer Reviewers
Jean-Pierre Bellier;
Jens-Ulrich Rahfeld
- Funders
- Ontario Genomics
- Mitacs
- National Institutes of Aging
- Genome Canada
Research Article
metrics
Revised
Reversine enhances the conversion of dedifferentiated fat cells into mature cardiomyocytes
[version 3; peer review: 2 approved]
Peer Reviewers
Francesco Galli;
Jelena Milasin
Research Article
metrics
Revised
Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine
[version 2; peer review: 2 approved]
Peer Reviewers
Putri Dianita Ika Meilia;
Ankita Guleria
- Funder
- The author (s) declared that no grants were involved in supporting this work.
Review
metrics
Revised
Essential growth factor receptors for fibroblast homeostasis and activation: Fibroblast Growth Factor Receptor (FGFR), Platelet Derived Growth Factor Receptor (PDGFR), and Transforming Growth Factor β Receptor (TGFβR)
[version 2; peer review: 2 approved]
Peer Reviewers
Natalia Pikor;
Michelle D Tallquist
- Funder
- Canadian Institutes of Health Research
Brief Report
metrics
SARS-CoV-2-ORF3a variant Q57H reduces its pro-apoptotic activity in host cells
[version 1; peer review: 1 approved with reservations, 1 not approved]
Peer Reviewers
Julian Leibowitz and Sarisa Na Pombejra;
Wei Liu
- Funders
- American Heart Association
- Institute of Engineering in Medicine at University of Minnesota
- National Heart, Lung, and Blood Institute
- Office of Academic Clinical Affairs at University of Minnesota
Research Article
metrics
Revised
Efficacy of mesenchymal stem cells cultured low oxygen tension ameliorates apoptotic inhibitors, viability, and differentiation of ovarian tissue: A study in a rat model with ovarian failure
[version 3; peer review: 2 approved, 1 not approved]
Peer Reviewers
Deepa Bhartiya;
Zezheng Pan;
Raheleh Farahzadi
- Funder
- Ministry of Education, Culture, Research and Technology, Republic of Indonesia
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Viyatprajna Acharya;
Oi Wah Liew;
Lynne Howells
- Funders
- Ontario Genomics
- Mitacs
- National Institutes of Aging
- Genome Canada
Method Article
metrics
Revised
Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients
[version 2; peer review: 2 approved]
Peer Reviewers
Natividad Gomez-Roman;
Anke Brüning-Richardson
- Funders
- Urology Foundation
- Brain Tumour Charity
- Weston Park Cancer Charity
- National Centre for the Replacement Refinement and Reduction of Animals in Research