Cell & Molecular Biology
Cell & Molecular Biology
Method Article
metrics
Revised
A detailed methodology for a three-dimensional, self-structuring bone model that supports the differentiation of osteoblasts towards osteocytes and the production of a complex collagen-rich mineralised matrix
[version 3; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers
Jesus Delgado-Calle and Hayley Sabol;
Holger Jahr;
Sabrina Ehnert;
Michelle A. Lawson
- Funders
- National Centre for the Replacement, Refinement and Reduction of Animals in Research
- Versus Arthritis
Data Note
metrics
Revised
The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
[version 2; peer review: 2 approved]
Peer Reviewers
Yasukazu Takanezawa;
Guoqiang Xu
- Funders
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- ALS Society of Canada
- ALS Association
- Motor Neurone Disease Association
- Genome Quebec
- Mitacs
- Genome Canada
Research Article
metrics
Revised
Unraveling the molecular mechanism of novel leukemia mutations on NTRK2 (A203T & R458G) and NTRK3 (E176D & L449F) genes using molecular dynamics simulations approach
[version 2; peer review: 3 approved]
Peer Reviewers
Dicson Sheeja Malar;
Gurudeeban Selvaraj;
Rajasekaran R.
- Funder
- This work was primarily supported by grants from the Deanship of Scientific Research, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Research Article
metrics
Revised
Reversine enhances the conversion of dedifferentiated fat cells into mature cardiomyocytes
[version 3; peer review: 2 approved]
Peer Reviewers
Francesco Galli;
Jelena Milasin
Research Article
metrics
Revised
Wings of Change: aPKC/FoxP-dependent plasticity in steering motor neurons underlies operant self-learning in Drosophila
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Efthimios M C Skoulakis;
Kathrin Vogt;
Wayne Sossin
- Funder
- Deutsche Forschungsgemeinschaft
Research Article
metrics
Revised
A potential role of arcadia in conditioned media - umbilical cord derived mesenchymal stem cell on cartilage repair
[version 2; peer review: 1 approved with reservations, 3 not approved]
Peer Reviewers
William Mark Erwin;
Girish Pattappa;
Rajesh Ramasamy;
Jeanne Adiwinata Pawitan
Research Article
metrics
Revised
Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine
[version 2; peer review: 2 approved]
Peer Reviewers
Putri Dianita Ika Meilia;
Ankita Guleria
- Funder
- The author (s) declared that no grants were involved in supporting this work.
Review
metrics
Revised
Essential growth factor receptors for fibroblast homeostasis and activation: Fibroblast Growth Factor Receptor (FGFR), Platelet Derived Growth Factor Receptor (PDGFR), and Transforming Growth Factor β Receptor (TGFβR)
[version 2; peer review: 2 approved]
Peer Reviewers
Natalia Pikor;
Michelle D Tallquist
- Funder
- Canadian Institutes of Health Research
Software Tool Article
metrics
Revised
GARCOM: A user-friendly R package for genetic mutation counts
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Ettore Mosca;
Stephen M. Pederson;
Tao Wang
- Funder
- National Institute of Aging
Software Tool Article
metrics
Revised
BASiCS workflow: a step-by-step analysis of expression variability using single cell RNA sequencing data
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Oliver M. Crook;
Andrew McDavid;
Michel S Naslavsky
- Funders
- Cancer Research UK
- University of Edinburgh
- European Molecular Biology Laboratory
Study Protocol
metrics
VDR mRNA Expression And Serum Vitamin D Levels in Post-Covid Vaccinated Patients
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Gaurav Kaushik;
Olga Adriana Caliman-Sturdza
Brief Report
metrics
SARS-CoV-2-ORF3a variant Q57H reduces its pro-apoptotic activity in host cells
[version 1; peer review: 1 approved with reservations, 1 not approved]
Peer Reviewers
Julian Leibowitz and Sarisa Na Pombejra;
Wei Liu
- Funders
- American Heart Association
- Institute of Engineering in Medicine at University of Minnesota
- National Heart, Lung, and Blood Institute
- Office of Academic Clinical Affairs at University of Minnesota
Brief Report
metrics
Revised
Validation and in vivo characterization of research antibodies for Moesin, CD44, Midkine, and sFRP-1.
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Sarah C Hopp and Caitlyn Fastenau;
Michelle Erickson;
Steve Jean
- Funders
- Government of Canada
- National Institutes of Aging
Research Article
metrics
Revised
Are circadian amplitudes and periods correlated? A new twist in the story
[version 2; peer review: 3 approved]
Peer Reviewers
Jihwan Myung;
Stephanie Taylor;
Jae Kim
- Funder
- Deutsche Forschungsgemeinschaft
Research Article
metrics
Revised
Efficacy of mesenchymal stem cells cultured low oxygen tension ameliorates apoptotic inhibitors, viability, and differentiation of ovarian tissue: A study in a rat model with ovarian failure
[version 3; peer review: 2 approved, 1 not approved]
Peer Reviewers
Deepa Bhartiya;
Zezheng Pan;
Raheleh Farahzadi
- Funder
- Ministry of Education, Culture, Research and Technology, Republic of Indonesia
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence
[version 2; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers
Amal Kaddoumi;
Jens-Ulrich Rahfeld;
Jieya Shao;
Karen Bowman
- Funders
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- Genome Quebec
- Mitacs
- Genome Canada
- National Institutes of Aging
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence
[version 2; peer review: 2 approved]
Peer Reviewers
Claudia Fallini;
Jozsef Gal
- Funders
- Bristol-Myers Squibb
- Takeda
- ALS Society of Canada
- Pfizer
- Motor Neurone Disease Association
- Genome Quebec
- Genentech
- Ontario Genomics
- Canadian Institutes of Health Research Foundation
- Janssen
- Bayer AG
- Boehringer Ingelheim
- Merck KGaA
- EUbOPEN
- ALS Association
- Mitacs
- Ontario Genomics Institute
Research Article
metrics
Revised
Assessing the potential relevance of CEACAM6 as a blood transcriptional biomarker
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Mattia Lauriola;
Ritu Pandey and Daruka Mahadevan;
Akila Prashant and Deepthi V
Data Note
metrics
Revised
A guide to selecting high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Viyatprajna Acharya;
Oi Wah Liew;
Lynne Howells
- Funders
- Ontario Genomics
- Mitacs
- National Institutes of Aging
- Genome Canada
Method Article
metrics
Revised
Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients
[version 2; peer review: 2 approved]
Peer Reviewers
Natividad Gomez-Roman;
Anke Brüning-Richardson
- Funders
- Urology Foundation
- Brain Tumour Charity
- Weston Park Cancer Charity
- National Centre for the Replacement Refinement and Reduction of Animals in Research